Syed Mohd Jeffri Syed Jaafar merupakan anak kelahiran Temerloh Pahang. Beliau merupakan lulusan cemerlang Sarjana Muda Syariah  (Fiqh & Usul)  daripada Universiti Malaya pada tahun 2012 di bawah tajaan Jabatan Perkhidmatan Awam (JPA). Pada tahun 2013, beliau telah ditawarkan menyambung pengajian di peringkat doktor falsafah secara fast track dalam bidang fiqh dan Usul  di Universiti yang sama dengan mendapat tajaan Skim Latihan Akademik IPTA (SLAI).  Beliau telah berjaya menyelesaikan pengajian dengan GOT “Graduate on Time” di peringkat doktor falsafah pada tahun 2017. Sepanjang pengajian, beliau sempat menimba ilmu di beberapa buah negara luar seperti di Jami’ah Ain Syam, Mesir (2010) dan di Dar Mustafa, Yaman (2014). Antara kepakaran dan bidang yang sedang diterokai oleh beliau adalah usul fiqh, pemikiran hukum, fiqh ibadat, fiqh haji dan umrah serta fiqh kontemporari. Beliau seorang yang aktif di dalam penyelidikan, penulisan, penerbitan dan persidangan baik di peringkat kebangsaan mahupun antarabangsa. Kini beliau berkhidmat sebagai pensyarah kanan di Jabatan Fiqh dan Usul, Akademi Pengajian Islam, Universiti Malaya.

Dr Shamsul became a member of the Universiti Malaya faculty in 2017, where he works as an academic lecturer in the Department of Pharmacology within the Faculty of Medicine. Before that, during his two years as a postdoctoral fellow, he focused on molecular studies related to liver diseases, including drug-induced liver injury and non-alcoholic fatty liver disease. He holds multiple roles within the department, including Head of the Pharmacogenomics Laboratory, Quality Manager, Year-2 and Postgraduates Pharmacology Course Coordinator for dental programme, and Academic Advisor for postgraduate students. Additionally, he is a member of the faculty's Postgraduates Committee (JKITF) and Internationalisation Unit (IUFOM). Also, he holds the position of a contributing Associate Editor for the Malaysian Applied Biology Journal. He is an external examiner of a Pharmacy course programme for Kolej Universiti Antarabangsa MAIWP (UCMI). He is also the Chair and founder of the Malaysia-Taiwan Forum for Evidenced-Based Medicine, and maintains an active role as an associate member of the South East Asian Pharmacogenomics Network (SEAPharm). He is currently overseeing the progress of three PhD candidates and has successfully graduated three PhD and four master's degree graduates. He has a strong focus on clinical and molecular hepatology, pharmacogenomics, and other omics-related research, with an impressive track record of over 40 publications.

2005- 2007 : PhD Degree in Islamic Philosophy, Faculty of Usul al-Din, Academy of Islamic Studies. University of Malaya (UM), Malaysia.2000 – 2003 : Master Degree in Usul al-Din with CGPA of 81% and a rating of very good. Faculty of Islamic Studies. Islamic University Baghdad, Iraq.1996-2000 : Bachelor Degree in Islamic Shari'ah with CGPA of 80.52% and a rating of very good, Faculty of Islamic Studies. Islamic University Baghdad, Iraq.WORKING EXPERIENCES • Assistant Lecturer (Part-timer) at Mu'ta University taught Islamic civilization (From 2003 to 2005).• Assistant lecturer (Part time) at University of Malaya (UM), teaching • Professor Assistance (Lecturer) in King Faisal University / KSA from 2008 till now 2018. • Professor Assistant in Islamic University of Minnesota‎‏.• Senior Lecturer in University of Malaya (UM) from 2019 till now.