ARTICLE IN ACADEMIC JOURNALS
| NO | DETAILS OF ARTICLE IN ACADEMIC JOURNALS |
|---|---|
| 1. |
A comprehensive review on potential drug-drug interactions of proton pump inhibitors with antidiabetic drugs metformin and DPP-4 inhibitors
2024
Author(s) : Najihah Binti Mohd Hashim, Heh Choon Han Source :
CELL BIOCHEMISTRY AND FUNCTION
DOI :
10.1002/cbf.3967
|
| 2. |
An immunoinformatic approach to assessing the immunogenic capacity of alpha-neurotoxins in elapid snake venoms
2023
Author(s) : Tan Choo Hock, Heh Choon Han Source :
FRONTIERS IN PHARMACOLOGY
DOI :
10.3389/fphar.2023.1143437
|
| 3. |
Automated in silico EGFR Peptide Inhibitor Elongation using Self-evolving Peptide Algorithm
2022
Author(s) : Heh Choon Han, Chin Sek Peng Source :
CURRENT COMPUTER-AIDED DRUG DESIGN
DOI :
10.2174/1573409918666220516144300
|
| 4. |
A Reverse Structure-based Design of HPV E7 Inhibitor
2022
Source :
CURRENT COMPUTER-AIDED DRUG DESIGN
DOI :
10.2174/1573409918666220509214449
|
| 5. |
Phytochemicals of six selected herbal plants and their inhibitory activities towards free radicals and glycation
2022
Source :
FOOD BIOSCIENCE
DOI :
10.1016/j.fbio.2022.101557
|
| 6. |
Development of flexible electrochemical impedance spectroscopy-based biosensing platform for rapid screening of SARS-CoV-2 inhibitors
2021
Author(s) : Adeeba Binti Kamarulzaman, Chung Lip Yong, Ng Chirk Jenn, Kiew Lik Voon, Leo Bey Fen, Heh Choon Han, Foo Yiing Yee Source :
BIOSENSORS & BIOELECTRONICS
DOI :
10.1016/j.bios.2021.113213
|
| 7. |
Triorganotin complexes in cancer chemotherapy: Mechanistic insights and future perspectives
2021
Source :
APPLIED ORGANOMETALLIC CHEMISTRY
DOI :
10.1002/aoc.6089
|
| 8. |
Rational drug discovery: Ellagic acid as a potent dual-target inhibitor against hepatitis C virus genotype 3 (HCV G3) NS3 enzymes
2021
Source :
CHEMICAL BIOLOGY & DRUG DESIGN
DOI :
10.1111/cbdd.13756
|
| 9. |
In-silico Studies of the Antiproliferative Activity of New Anilinoquinazoline Derivatives Against NSCLC Cells
2021
Source :
JOURNAL OF MOLECULAR STRUCTURE
DOI :
10.1016/j.molstruc.2020.129786
|
| 10. |
Development of MTH1-Binding Nucleotide Analogs Based on 7,8-Dihalogenated 7-Deaza-dG Derivatives
2021
Author(s) : Heh Choon Han Source :
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
DOI :
10.3390/ijms22031274
|
| 11. |
Synthesis, In Vitro Antiproliferative Activity, and In Silico Studies of New Anilinoquinazoline Derivatives as Potential AntitumorAgents
2020
Source :
RUSSIAN JOURNAL OF GENERAL CHEMISTRY
DOI :
10.1134/S1070363220120294
|
| 12. |
Discovery of Dengue Virus Inhibitors
2020
Source :
Current Medicinal Chemistry
DOI :
10.2174/0929867326666181204155336
|
| 13. |
Synthesis of c-N-modified 8-oxo-2 -deoxyguanosine triphosphate and its characterization
2019
Author(s) : Heh Choon Han, Leong Kok Hoong Source :
Nucleosides, Nucleotides and Nucleic Acids
DOI :
10.1080/15257770.2019.1586919
|
| 14. |
Sofosbuvir as treatment against dengue?
2017
Author(s) : Heh Choon Han, Chee Chin Fei Source :
Chemical Biology & Drug Design
DOI :
10.1111/cbdd.13091
|
| 15. |
The synthetic molecules YK51 and YK73 attenuate replication of dengue virus serotype 2.
2017
Author(s) : Heh Choon Han Source :
Tropical Biomedicine
|
| 16. |
Phosphodiesterase-5 inhibitors and their analogues as adulterants of herbal and food products: analysis of the Malaysian market in 2014-2016.
2017
Author(s) : Heh Choon Han Source :
Food Additives & Contaminants: Part A
DOI :
10.1080/19440049.2017.1336674
|
| 17. |
Rational drug discovery of HCV helicase inhibitor: Improved docking accuracy with multiple seedings of Autodock Vina and in situ minimization.
2016
Author(s) : Heh Choon Han, Rozana Binti Othman Source :
Current Computer-Aided Drug Design
DOI :
10.2174/15734099126661611301226
|
| 18. |
Prevalence of c.2268dup and detection of two novel alterations, c.670_672del and c.1186C>T, in the TPO gene in a cohort of Malaysian Chinese with thyroid dyshormonogenesis
2015
Source :
BMJ Open 2015
|
| 19. |
Variable clinical phenotypes in a family with homozygous c.1159G>A mutation in the thyroid peroxidase gene.
2014
Author(s) : Heh Choon Han Source :
Hormone Research in Paediatrics
|
| 20. |
Rational discovery of dengue type 2 non-competitive inhibitors.
2013
Author(s) : Heh Choon Han Source :
Chemical biology & drug design
|
| 21. |
A Novel, Homozygous c.1502T>G (p.Val501Gly) Mutation in the Thyroid peroxidase Gene in Malaysian Sisters with Congenital Hypothyroidism and Multinodular Goiter
2013
Author(s) : Heh Choon Han Source :
International Journal of Endocrinology
|
| 22. |
Boesenbergia rotunda: From Ethnomedicine to Drug Discovery.
2012
Author(s) : Heh Choon Han Source :
Evidence-Based Complementary and Alternative Medicine
|
| 23. |
Inhibition of dengue NS2B-NS3 protease and viral replication in Vero cells by recombinant retrocyclin-1.
2012
Author(s) : Heh Choon Han Source :
BMC Infectious Diseases
|
CHAPTER IN BOOK
| NO | DETAILS OF CHAPTER IN BOOK |
|---|---|
| 1. |
Rational Drug Discovery: Virtual Screening of DEN-2 Non-competitive Inhibitors.
2016
Author(s) : Heh Choon Han |
RESEARCH PROJECT
| GRANT | PROGRESS | STATUS |
|---|---|---|
|
A Mechanistic Study To Identify The Upstream Therapeutic Target Of Tribenzyltin Carboxylates For Improving Cancer Chemotherapy
|
|
end |
|
In Silico Self-evolving Peptides Algorithm For The Discovery Of Potential Peptide Inhibitor Against Alpha-amylase And Alpha-glucosidase
|
|
end |
|
Insight Into The Binding Mechanism Of Quinazoline Derivatives Against Non-mutated And Mutated Egfrs
Researcher(s) : Prof. Dr. Azhar Bin Ariffin |
|
end |
|
Rational Discovery of Novel Hepatitis C Virus Inhibitors--An in silico approach targeting HCV serine protease and helicase
Researcher(s) : - |
|
end |
|
Rational Discovery Of Novel Hepatitis C Virus Inhibitors
Researcher(s) : Associate Prof. Dr. Rozana Binti Othman |
|
end |
|
DEVELOPMENT OF A LIQUID CHROMATOGRAPHY MASS SPECTROMETRY (LCMS) METHOD FOR PHOSPHODIESTERASE-5 INHIBITORS
Researcher(s) : - |
|
end |
|
Small Peptide Design For Anti Inflammatory Activity
|
|
end |
|
Discovery of Novel Inhibitors for Hepatitis C Virus via Virtual Screening
Researcher(s) : Associate Prof. Dr. Rozana Binti Othman |
|
end |
RESEARCH COLLABORATOR
| GRANT | PROGRESS | STATUS |
|---|---|---|
|
Deep Learning In Molecular Descriptors Mining And Optimization For Drug-potentials Targeting G Protein-coupled Receptors
Researcher(s) : Prof. Dr. Vannajan Sanghiran Lee, Dr. Heh Choon Han, Dr. Saw Shier Nee, Dr. Nurul Binti Japar, Assoc. Prof. Ts. Ir. Dr. Mohammad Lutfi Othman, - |
|
on going |
|
Satreps : The Trilateral Collaboration Project For Anti-infectious Disease Drug Development: From Lead Optimization To Preclinical Testing
|
|
on going |
|
Investigating Factors Affecting Aptamer?s Conformation And Target Sensitivity At The Aptamer-graphene Interface And Mechanism Description For Biosensing Applications
Researcher(s) : Dr. Chin Sek Peng, Prof. Dr. Thong Kwai Lin, Dr. Heh Choon Han, Dr. Subhashini A/p Raj Kumal |
|
on going |
|
Investigations Into The Poor Neutralization Efficacy Of Cobra Antivenom Against Lethal Cobra Neurotoxins Through In Vitro, In Vivo And In Silico Studies
Researcher(s) : Prof. Dr. Tan Nget Hong, Associate Prof. Dr. Tan Choo Hock, Dr. Heh Choon Han, Dr. Ng Tzu Shan |
|
end |
|
Pharmaceutical Excipient Development: Converting Sago Starch As A Direct Compression Tablet Excipient
Researcher(s) : Dr. Heh Choon Han, M. Mothilal |
|
end |
|
Interdisciplinary And Target-based Development Of Nutraceuticals And Drugs For Prevention And Treatments Of Diseases
Researcher(s) : Dr. Heh Choon Han, Dr. Chee Chin Fei |
|
end |
|
Understanding Release Characteristics And Pharmacokinetics Study Of Encapsulated Nanoparticle Gel Transdermal Delivery Of Testosterone
Researcher(s) : Dr. Heh Choon Han, Prof. Dr. Zamri Bin Chik |
|
end |
|
Unravelling The Antineoplastic Mechanism Of Anilinoquinazoline Compound In Lung Cancer Stem Cells And Zebrafish
|
|
end |
|
Multiscale Refinement Of Cryo-electron Microscopy Data For Structural Analysis And Mechanism Study Of Biological Macromolecules
|
|
end |
|
Virtual Screening Of Peptide-cell Membrane
Researcher(s) : Dr. Heh Choon Han |
|
end |