ARTICLE IN ACADEMIC JOURNALS
| NO | DETAILS OF ARTICLE IN ACADEMIC JOURNALS |
|---|---|
| 1. |
Phytochemicals of six selected herbal plants and their inhibitory activities towards free radicals and glycation
2022
Source : FOOD BIOSCIENCE DOI : 10.1016/j.fbio.2022.101557 |
| 2. |
Automated in silico EGFR Peptide Inhibitor Elongation using Self-evolving Peptide Algorithm
2022
Author(s) : Heh Choon Han,Chin Sek Peng Source : CURRENT COMPUTER-AIDED DRUG DESIGN DOI : 10.2174/1573409918666220516144300 |
| 3. |
In-silico Studies of the Antiproliferative Activity of New Anilinoquinazoline Derivatives Against NSCLC Cells
2021
Source : JOURNAL OF MOLECULAR STRUCTURE DOI : 10.1016/j.molstruc.2020.129786 |
| 4. |
Rational drug discovery: Ellagic acid as a potent dual-target inhibitor against hepatitis C virus genotype 3 (HCV G3) NS3 enzymes
2021
Source : CHEMICAL BIOLOGY & DRUG DESIGN DOI : 10.1111/cbdd.13756 |
| 5. |
Triorganotin complexes in cancer chemotherapy: Mechanistic insights and future perspectives
2021
Source : APPLIED ORGANOMETALLIC CHEMISTRY DOI : 10.1002/aoc.6089 |
| 6. |
Development of flexible electrochemical impedance spectroscopy-based biosensing platform for rapid screening of SARS-CoV-2 inhibitors
2021
Author(s) : Adeeba Binti Kamarulzaman,Chung Lip Yong,Ng Chirk Jenn,Kiew Lik Voon,Leo Bey Fen,Heh Choon Han,Foo Yiing Yee Source : BIOSENSORS & BIOELECTRONICS DOI : 10.1016/j.bios.2021.113213 |
| 7. |
Development of MTH1-Binding Nucleotide Analogs Based on 7,8-Dihalogenated 7-Deaza-dG Derivatives
2021
Author(s) : Heh Choon Han Source : INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES DOI : 10.3390/ijms22031274 |
| 8. |
Discovery of Dengue Virus Inhibitors
2020
Source : Current Medicinal Chemistry DOI : 10.2174/0929867326666181204155336 |
| 9. |
Synthesis of c-N-modified 8-oxo-2 -deoxyguanosine triphosphate and its characterization
2019
Author(s) : Leong Kok Hoong,Heh Choon Han Source : Nucleosides, Nucleotides and Nucleic Acids DOI : 10.1080/15257770.2019.1586919 |
| 10. |
Sofosbuvir as treatment against dengue?
2017
Author(s) : Chee Chin Fei,Heh Choon Han Source : Chemical Biology & Drug Design DOI : 10.1111/cbdd.13091 |
| 11. |
Phosphodiesterase-5 inhibitors and their analogues as adulterants of herbal and food products: analysis of the Malaysian market in 2014-2016.
2017
Author(s) : Heh Choon Han Source : Food Additives & Contaminants: Part A DOI : 10.1080/19440049.2017.1336674 |
| 12. |
The synthetic molecules YK51 and YK73 attenuate replication of dengue virus serotype 2.
2017
Author(s) : Heh Choon Han Source : Tropical Biomedicine |
| 13. |
Rational drug discovery of HCV helicase inhibitor: Improved docking accuracy with multiple seedings of Autodock Vina and in situ minimization.
2016
Author(s) : Rozana Binti Othman,Heh Choon Han Source : Current Computer-Aided Drug Design DOI : 10.2174/15734099126661611301226 |
| 14. |
Prevalence of c.2268dup and detection of two novel alterations, c.670_672del and c.1186C>T, in the TPO gene in a cohort of Malaysian Chinese with thyroid dyshormonogenesis
2015
Source : BMJ Open 2015 |
| 15. |
Variable clinical phenotypes in a family with homozygous c.1159G>A mutation in the thyroid peroxidase gene.
2014
Author(s) : Heh Choon Han Source : Hormone Research in Paediatrics |
| 16. |
Rational discovery of dengue type 2 non-competitive inhibitors.
2013
Author(s) : Heh Choon Han Source : Chemical biology & drug design |
| 17. |
A Novel, Homozygous c.1502T>G (p.Val501Gly) Mutation in the Thyroid peroxidase Gene in Malaysian Sisters with Congenital Hypothyroidism and Multinodular Goiter
2013
Author(s) : Heh Choon Han Source : International Journal of Endocrinology |
| 18. |
Boesenbergia rotunda: From Ethnomedicine to Drug Discovery.
2012
Author(s) : Heh Choon Han Source : Evidence-Based Complementary and Alternative Medicine |
| 19. |
Inhibition of dengue NS2B-NS3 protease and viral replication in Vero cells by recombinant retrocyclin-1.
2012
Author(s) : Heh Choon Han Source : BMC Infectious Diseases |
CHAPTER IN BOOK
| NO | DETAILS OF CHAPTER IN BOOK |
|---|---|
| 1. |
Rational Drug Discovery: Virtual Screening of DEN-2 Non-competitive Inhibitors.
2016
Author(s) : Heh Choon Han |
RESEARCH PROJECT
| GRANT | PROGRESS | STATUS |
|---|---|---|
|
Insight Into The Binding Mechanism Of Quinazoline Derivatives Against Non-mutated And Mutated Egfrs
Researcher(s) : Prof. Dr. Azhar Bin Ariffin
(Geran Penyelidikan Universiti Malaya (UMRG Programme) - AFR (Frontier Science)) |
|
end |
|
Rational Discovery of Novel Hepatitis C Virus Inhibitors--An in silico approach targeting HCV serine protease and helicase
Researcher(s) : -
(Postgraduate Research Grant (PPP) - Research) |
|
end |
|
Rational Discovery Of Novel Hepatitis C Virus Inhibitors
Researcher(s) : Associate Prof. Dr. Rozana Binti Othman
(Bantuan Khas Penyelidikan (BKP Special)) |
|
end |
|
DEVELOPMENT OF A LIQUID CHROMATOGRAPHY MASS SPECTROMETRY (LCMS) METHOD FOR PHOSPHODIESTERASE-5 INHIBITORS
Researcher(s) : -
(Postgraduate Research Grant (PPP) - Research) |
|
end |
|
Small Peptide Design For Anti Inflammatory Activity
(Private Funding) |
|
end |
|
Discovery of Novel Inhibitors for Hepatitis C Virus via Virtual Screening
Researcher(s) : Associate Prof. Dr. Rozana Binti Othman
(Bantuan Kecil Penyelidikan (BKP)) |
|
end |
RESEARCH COLLABORATOR
| GRANT | PROGRESS | STATUS |
|---|---|---|
|
Investigating Factors Affecting Aptamer’s Conformation And Target Sensitivity At The Aptamer-graphene Interface And Mechanism Description For Biosensing Applications
Researcher(s) : Dr. Chin Sek Peng,Prof. Dr. Thong Kwai Lin,Dr. Heh Choon Han,Dr. Subhashini A/p Raj Kumal
(Fundamental Research Grant Scheme (FRGS)) |
|
new |
|
Interdisciplinary And Target-based Development Of Nutraceuticals And Drugs For Prevention And Treatments Of Diseases
Researcher(s) : Dr. Heh Choon Han,Dr. Chee Chin Fei
(RU Geran) |
|
on going |
|
Investigations Into The Poor Neutralization Efficacy Of Cobra Antivenom Against Lethal Cobra Neurotoxins Through In Vitro, In Vivo And In Silico Studies
Researcher(s) : Prof. Dr. Tan Nget Hong,Associate Prof. Dr. Tan Choo Hock,Dr. Heh Choon Han,Dr. Ng Tzu Shan
(Fundamental Research Grant Scheme (FRGS)) |
|
on going |
|
Understanding Release Characteristics And Pharmacokinetics Study Of Encapsulated Nanoparticle Gel Transdermal Delivery Of Testosterone
Researcher(s) : Dr. Heh Choon Han,Prof. Dr. Zamri Bin Chik
(RU Geran - Fakulti Program) |
|
on going |
|
Multiscale Refinement Of Cryo-electron Microscopy Data For Structural Analysis And Mechanism Study Of Biological Macromolecules
Researcher(s) : Prof. Dr. Sharifuddin Bin Md Zain,Dr. Siti Munirah Binti Saharin,Associate Prof. Dr. Rozana Binti Othman,Dr. Heh Choon Han
(RU Geran - Fakulti Program) |
|
end |
|
Quantum Mechanics, Molecular Mechanics, And Molecular Dynamics Simulations For Mechanism Studies Of Protein Function Using Cloud Computing
Researcher(s) : Associate Prof. Dr. Noor Idayu Binti Mat Zahid,Dr. Heh Choon Han,Prof. Dr. Rauzah Binti Hashim
(Geran Penyelidikan Universiti Malaya (UMRG Programme) - AFR (Frontier Science)) |
|
end |
|
Virtual Screening Of Peptide-cell Membrane
Researcher(s) : Dr. Heh Choon Han
(Geran Penyelidikan Universiti Malaya (UMRG Programme) - AFR (Frontier Science)) |
|
end |