ARTICLE IN ACADEMIC JOURNALS
NO | DETAILS OF ARTICLE IN ACADEMIC JOURNALS |
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1. |
An immunoinformatic approach to assessing the immunogenic capacity of alpha-neurotoxins in elapid snake venoms
2023
Author(s) : Tan Choo Hock,Heh Choon Han Source : FRONTIERS IN PHARMACOLOGY DOI : 10.3389/fphar.2023.1143437 |
2. |
A Reverse Structure-based Design of HPV E7 Inhibitor
2022
Source : CURRENT COMPUTER-AIDED DRUG DESIGN DOI : 10.2174/1573409918666220509214449 |
3. |
Phytochemicals of six selected herbal plants and their inhibitory activities towards free radicals and glycation
2022
Source : FOOD BIOSCIENCE DOI : 10.1016/j.fbio.2022.101557 |
4. |
Automated in silico EGFR Peptide Inhibitor Elongation using Self-evolving Peptide Algorithm
2022
Author(s) : Heh Choon Han,Chin Sek Peng Source : CURRENT COMPUTER-AIDED DRUG DESIGN DOI : 10.2174/1573409918666220516144300 |
5. |
Rational drug discovery: Ellagic acid as a potent dual-target inhibitor against hepatitis C virus genotype 3 (HCV G3) NS3 enzymes
2021
Source : CHEMICAL BIOLOGY & DRUG DESIGN DOI : 10.1111/cbdd.13756 |
6. |
Development of flexible electrochemical impedance spectroscopy-based biosensing platform for rapid screening of SARS-CoV-2 inhibitors
2021
Author(s) : Adeeba Binti Kamarulzaman,Chung Lip Yong,Ng Chirk Jenn,Kiew Lik Voon,Leo Bey Fen,Heh Choon Han,Foo Yiing Yee Source : BIOSENSORS & BIOELECTRONICS DOI : 10.1016/j.bios.2021.113213 |
7. |
In-silico Studies of the Antiproliferative Activity of New Anilinoquinazoline Derivatives Against NSCLC Cells
2021
Source : JOURNAL OF MOLECULAR STRUCTURE DOI : 10.1016/j.molstruc.2020.129786 |
8. |
Triorganotin complexes in cancer chemotherapy: Mechanistic insights and future perspectives
2021
Source : APPLIED ORGANOMETALLIC CHEMISTRY DOI : 10.1002/aoc.6089 |
9. |
Development of MTH1-Binding Nucleotide Analogs Based on 7,8-Dihalogenated 7-Deaza-dG Derivatives
2021
Author(s) : Heh Choon Han Source : INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES DOI : 10.3390/ijms22031274 |
10. |
Synthesis, In Vitro Antiproliferative Activity, and In Silico Studies of New Anilinoquinazoline Derivatives as Potential AntitumorAgents
2020
Source : RUSSIAN JOURNAL OF GENERAL CHEMISTRY DOI : 10.1134/S1070363220120294 |
11. |
Discovery of Dengue Virus Inhibitors
2020
Source : Current Medicinal Chemistry DOI : 10.2174/0929867326666181204155336 |
12. |
Synthesis of c-N-modified 8-oxo-2 -deoxyguanosine triphosphate and its characterization
2019
Author(s) : Leong Kok Hoong,Heh Choon Han Source : Nucleosides, Nucleotides and Nucleic Acids DOI : 10.1080/15257770.2019.1586919 |
13. |
Sofosbuvir as treatment against dengue?
2017
Author(s) : Chee Chin Fei,Heh Choon Han Source : Chemical Biology & Drug Design DOI : 10.1111/cbdd.13091 |
14. |
The synthetic molecules YK51 and YK73 attenuate replication of dengue virus serotype 2.
2017
Author(s) : Heh Choon Han Source : Tropical Biomedicine |
15. |
Phosphodiesterase-5 inhibitors and their analogues as adulterants of herbal and food products: analysis of the Malaysian market in 2014-2016.
2017
Author(s) : Heh Choon Han Source : Food Additives & Contaminants: Part A DOI : 10.1080/19440049.2017.1336674 |
16. |
Rational drug discovery of HCV helicase inhibitor: Improved docking accuracy with multiple seedings of Autodock Vina and in situ minimization.
2016
Author(s) : Rozana Binti Othman,Heh Choon Han Source : Current Computer-Aided Drug Design DOI : 10.2174/15734099126661611301226 |
17. |
Prevalence of c.2268dup and detection of two novel alterations, c.670_672del and c.1186C>T, in the TPO gene in a cohort of Malaysian Chinese with thyroid dyshormonogenesis
2015
Source : BMJ Open 2015 |
18. |
Variable clinical phenotypes in a family with homozygous c.1159G>A mutation in the thyroid peroxidase gene.
2014
Author(s) : Heh Choon Han Source : Hormone Research in Paediatrics |
19. |
Rational discovery of dengue type 2 non-competitive inhibitors.
2013
Author(s) : Heh Choon Han Source : Chemical biology & drug design |
20. |
A Novel, Homozygous c.1502T>G (p.Val501Gly) Mutation in the Thyroid peroxidase Gene in Malaysian Sisters with Congenital Hypothyroidism and Multinodular Goiter
2013
Author(s) : Heh Choon Han Source : International Journal of Endocrinology |
21. |
Boesenbergia rotunda: From Ethnomedicine to Drug Discovery.
2012
Author(s) : Heh Choon Han Source : Evidence-Based Complementary and Alternative Medicine |
22. |
Inhibition of dengue NS2B-NS3 protease and viral replication in Vero cells by recombinant retrocyclin-1.
2012
Author(s) : Heh Choon Han Source : BMC Infectious Diseases |
CHAPTER IN BOOK
NO | DETAILS OF CHAPTER IN BOOK |
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1. |
Rational Drug Discovery: Virtual Screening of DEN-2 Non-competitive Inhibitors.
2016
Author(s) : Heh Choon Han |
RESEARCH PROJECT
GRANT | PROGRESS | STATUS |
---|---|---|
A Mechanistic Study To Identify The Upstream Therapeutic Target Of Tribenzyltin Carboxylates For Improving Cancer Chemotherapy
(Fundamental Research Grant Scheme (FRGS)) |
|
end |
In Silico Self-evolving Peptides Algorithm For The Discovery Of Potential Peptide Inhibitor Against Alpha-amylase And Alpha-glucosidase
(Fundamental Research Grant Scheme (FRGS)) |
|
end |
Insight Into The Binding Mechanism Of Quinazoline Derivatives Against Non-mutated And Mutated Egfrs
Researcher(s) : Prof. Dr. Azhar Bin Ariffin
(Geran Penyelidikan Universiti Malaya (UMRG Programme) - AFR (Frontier Science)) |
|
end |
Rational Discovery of Novel Hepatitis C Virus Inhibitors--An in silico approach targeting HCV serine protease and helicase
Researcher(s) : -
(Postgraduate Research Grant (PPP) - Research) |
|
end |
Rational Discovery Of Novel Hepatitis C Virus Inhibitors
Researcher(s) : Associate Prof. Dr. Rozana Binti Othman
(Bantuan Khas Penyelidikan (BKP Special)) |
|
end |
DEVELOPMENT OF A LIQUID CHROMATOGRAPHY MASS SPECTROMETRY (LCMS) METHOD FOR PHOSPHODIESTERASE-5 INHIBITORS
Researcher(s) : -
(Postgraduate Research Grant (PPP) - Research) |
|
end |
Small Peptide Design For Anti Inflammatory Activity
(Private Funding) |
|
end |
Discovery of Novel Inhibitors for Hepatitis C Virus via Virtual Screening
Researcher(s) : Associate Prof. Dr. Rozana Binti Othman
(Bantuan Kecil Penyelidikan (BKP)) |
|
end |
RESEARCH COLLABORATOR
GRANT | PROGRESS | STATUS |
---|---|---|
Deep Learning In Molecular Descriptors Mining And Optimization For Drug-potentials Targeting G Protein-coupled Receptors
Deprecated: strtolower(): Passing null to parameter #1 ($string) of type string is deprecated in /var/www/html/umexpertv3/included_view/vw_collaborator_research.php on line 159 Researcher(s) : Associate Prof. Dr. Vannajan Sanghiran Lee,Dr. Heh Choon Han,Dr. Saw Shier Nee,Dr. Nurul Binti Japar,Assoc. Prof. Ts. Ir. Dr. Mohammad Lutfi Othman
(Fundamental Research Grant Scheme (FRGS)) |
|
new |
SATREPS : The Trilateral Collaboration Project for Anti-infectious Disease Drug Development: From Lead Optimization to Preclinical Testing
Researcher(s) : Associate Prof. Dr. Choo Yeun Mun,Associate Prof. Dr. Rozana Binti Othman,Associate Prof. Dr. Shatrah Binti Othman,Associate Prof. Dr. Vannajan Sanghiran Lee,Dr. Iskandar Bin Abdullah,Dr. Lee Yean Kee,Associate Prof. Dr. Nurshamimi Bte Nor Rashid,Dr. Abdullah Al-hadi Bin Ahmad Fuaad,Dr. Heh Choon Han
(International Funding) |
|
on going |
Investigating Factors Affecting Aptamer?s Conformation And Target Sensitivity At The Aptamer-graphene Interface And Mechanism Description For Biosensing Applications
Researcher(s) : Dr. Chin Sek Peng,Prof. Dr. Thong Kwai Lin,Dr. Heh Choon Han,Dr. Subhashini A/p Raj Kumal
(Fundamental Research Grant Scheme (FRGS)) |
|
on going |
Pharmaceutical Excipient Development: Converting sago starch as a direct compression tablet excipient
Researcher(s) : Dr. Heh Choon Han,M. Mothilal
(UM International Collaboration Grant) |
|
on going |
Interdisciplinary And Target-based Development Of Nutraceuticals And Drugs For Prevention And Treatments Of Diseases
Researcher(s) : Dr. Heh Choon Han,Dr. Chee Chin Fei
(RU Geran) |
|
end |
Investigations Into The Poor Neutralization Efficacy Of Cobra Antivenom Against Lethal Cobra Neurotoxins Through In Vitro, In Vivo And In Silico Studies
Researcher(s) : Prof. Dr. Tan Nget Hong,Associate Prof. Dr. Tan Choo Hock,Dr. Heh Choon Han,Dr. Ng Tzu Shan
(Fundamental Research Grant Scheme (FRGS)) |
|
end |
Understanding Release Characteristics And Pharmacokinetics Study Of Encapsulated Nanoparticle Gel Transdermal Delivery Of Testosterone
Researcher(s) : Dr. Heh Choon Han,Prof. Dr. Zamri Bin Chik
(RU Geran - Fakulti Program) |
|
end |
Unravelling The Antineoplastic Mechanism Of Anilinoquinazoline Compound In Lung Cancer Stem Cells And Zebrafish
Researcher(s) : Prof. Dr. Azhar Bin Ariffin,Associate Prof. Dr. Anwar Bin Norazit,Dr. Kong Kin Weng,Dr. Heh Choon Han
(Fundamental Research Grant Scheme (FRGS)) |
|
end |
Multiscale Refinement Of Cryo-electron Microscopy Data For Structural Analysis And Mechanism Study Of Biological Macromolecules
Researcher(s) : Prof. Dr. Sharifuddin Bin Md Zain,Dr. Siti Munirah Binti Saharin,Associate Prof. Dr. Rozana Binti Othman,Dr. Heh Choon Han
(RU Geran - Fakulti Program) |
|
end |
Virtual Screening Of Peptide-cell Membrane
Researcher(s) : Dr. Heh Choon Han
(Geran Penyelidikan Universiti Malaya (UMRG Programme) - AFR (Frontier Science)) |
|
end |