ARTICLE IN ACADEMIC JOURNALS
NO | DETAILS OF ARTICLE IN ACADEMIC JOURNALS |
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1. |
A comprehensive review on potential drug-drug interactions of proton pump inhibitors with antidiabetic drugs metformin and DPP-4 inhibitors
2024
Author(s) : Najihah Binti Mohd Hashim, Heh Choon Han Source :
CELL BIOCHEMISTRY AND FUNCTION
DOI :
10.1002/cbf.3967
|
2. |
An immunoinformatic approach to assessing the immunogenic capacity of alpha-neurotoxins in elapid snake venoms
2023
Author(s) : Tan Choo Hock, Heh Choon Han Source :
FRONTIERS IN PHARMACOLOGY
DOI :
10.3389/fphar.2023.1143437
|
3. |
A Reverse Structure-based Design of HPV E7 Inhibitor
2022
Source :
CURRENT COMPUTER-AIDED DRUG DESIGN
DOI :
10.2174/1573409918666220509214449
|
4. |
Automated in silico EGFR Peptide Inhibitor Elongation using Self-evolving Peptide Algorithm
2022
Author(s) : Heh Choon Han, Chin Sek Peng Source :
CURRENT COMPUTER-AIDED DRUG DESIGN
DOI :
10.2174/1573409918666220516144300
|
5. |
Phytochemicals of six selected herbal plants and their inhibitory activities towards free radicals and glycation
2022
Source :
FOOD BIOSCIENCE
DOI :
10.1016/j.fbio.2022.101557
|
6. |
In-silico Studies of the Antiproliferative Activity of New Anilinoquinazoline Derivatives Against NSCLC Cells
2021
Source :
JOURNAL OF MOLECULAR STRUCTURE
DOI :
10.1016/j.molstruc.2020.129786
|
7. |
Triorganotin complexes in cancer chemotherapy: Mechanistic insights and future perspectives
2021
Source :
APPLIED ORGANOMETALLIC CHEMISTRY
DOI :
10.1002/aoc.6089
|
8. |
Rational drug discovery: Ellagic acid as a potent dual-target inhibitor against hepatitis C virus genotype 3 (HCV G3) NS3 enzymes
2021
Source :
CHEMICAL BIOLOGY & DRUG DESIGN
DOI :
10.1111/cbdd.13756
|
9. |
Development of MTH1-Binding Nucleotide Analogs Based on 7,8-Dihalogenated 7-Deaza-dG Derivatives
2021
Author(s) : Heh Choon Han Source :
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
DOI :
10.3390/ijms22031274
|
10. |
Development of flexible electrochemical impedance spectroscopy-based biosensing platform for rapid screening of SARS-CoV-2 inhibitors
2021
Author(s) : Adeeba Binti Kamarulzaman, Chung Lip Yong, Ng Chirk Jenn, Kiew Lik Voon, Leo Bey Fen, Heh Choon Han, Foo Yiing Yee Source :
BIOSENSORS & BIOELECTRONICS
DOI :
10.1016/j.bios.2021.113213
|
11. |
Synthesis, In Vitro Antiproliferative Activity, and In Silico Studies of New Anilinoquinazoline Derivatives as Potential AntitumorAgents
2020
Source :
RUSSIAN JOURNAL OF GENERAL CHEMISTRY
DOI :
10.1134/S1070363220120294
|
12. |
Discovery of Dengue Virus Inhibitors
2020
Source :
Current Medicinal Chemistry
DOI :
10.2174/0929867326666181204155336
|
13. |
Synthesis of c-N-modified 8-oxo-2 -deoxyguanosine triphosphate and its characterization
2019
Author(s) : Heh Choon Han, Leong Kok Hoong Source :
Nucleosides, Nucleotides and Nucleic Acids
DOI :
10.1080/15257770.2019.1586919
|
14. |
The synthetic molecules YK51 and YK73 attenuate replication of dengue virus serotype 2.
2017
Author(s) : Heh Choon Han Source :
Tropical Biomedicine
|
15. |
Phosphodiesterase-5 inhibitors and their analogues as adulterants of herbal and food products: analysis of the Malaysian market in 2014-2016.
2017
Author(s) : Heh Choon Han Source :
Food Additives & Contaminants: Part A
DOI :
10.1080/19440049.2017.1336674
|
16. |
Sofosbuvir as treatment against dengue?
2017
Author(s) : Heh Choon Han, Chee Chin Fei Source :
Chemical Biology & Drug Design
DOI :
10.1111/cbdd.13091
|
17. |
Rational drug discovery of HCV helicase inhibitor: Improved docking accuracy with multiple seedings of Autodock Vina and in situ minimization.
2016
Author(s) : Heh Choon Han, Rozana Binti Othman Source :
Current Computer-Aided Drug Design
DOI :
10.2174/15734099126661611301226
|
18. |
Prevalence of c.2268dup and detection of two novel alterations, c.670_672del and c.1186C>T, in the TPO gene in a cohort of Malaysian Chinese with thyroid dyshormonogenesis
2015
Source :
BMJ Open 2015
|
19. |
Variable clinical phenotypes in a family with homozygous c.1159G>A mutation in the thyroid peroxidase gene.
2014
Author(s) : Heh Choon Han Source :
Hormone Research in Paediatrics
|
20. |
A Novel, Homozygous c.1502T>G (p.Val501Gly) Mutation in the Thyroid peroxidase Gene in Malaysian Sisters with Congenital Hypothyroidism and Multinodular Goiter
2013
Author(s) : Heh Choon Han Source :
International Journal of Endocrinology
|
21. |
Rational discovery of dengue type 2 non-competitive inhibitors.
2013
Author(s) : Heh Choon Han Source :
Chemical biology & drug design
|
22. |
Inhibition of dengue NS2B-NS3 protease and viral replication in Vero cells by recombinant retrocyclin-1.
2012
Author(s) : Heh Choon Han Source :
BMC Infectious Diseases
|
23. |
Boesenbergia rotunda: From Ethnomedicine to Drug Discovery.
2012
Author(s) : Heh Choon Han Source :
Evidence-Based Complementary and Alternative Medicine
|
CHAPTER IN BOOK
NO | DETAILS OF CHAPTER IN BOOK |
---|---|
1. |
Rational Drug Discovery: Virtual Screening of DEN-2 Non-competitive Inhibitors.
2016
Author(s) : Heh Choon Han |
RESEARCH PROJECT
GRANT | PROGRESS | STATUS |
---|---|---|
A Mechanistic Study To Identify The Upstream Therapeutic Target Of Tribenzyltin Carboxylates For Improving Cancer Chemotherapy
|
|
end |
In Silico Self-evolving Peptides Algorithm For The Discovery Of Potential Peptide Inhibitor Against Alpha-amylase And Alpha-glucosidase
|
|
end |
Insight Into The Binding Mechanism Of Quinazoline Derivatives Against Non-mutated And Mutated Egfrs
Researcher(s) : Prof. Dr. Azhar Bin Ariffin |
|
end |
Rational Discovery of Novel Hepatitis C Virus Inhibitors--An in silico approach targeting HCV serine protease and helicase
Researcher(s) : - |
|
end |
Rational Discovery Of Novel Hepatitis C Virus Inhibitors
Researcher(s) : Associate Prof. Dr. Rozana Binti Othman |
|
end |
DEVELOPMENT OF A LIQUID CHROMATOGRAPHY MASS SPECTROMETRY (LCMS) METHOD FOR PHOSPHODIESTERASE-5 INHIBITORS
Researcher(s) : - |
|
end |
Small Peptide Design For Anti Inflammatory Activity
|
|
end |
Discovery of Novel Inhibitors for Hepatitis C Virus via Virtual Screening
Researcher(s) : Associate Prof. Dr. Rozana Binti Othman |
|
end |
RESEARCH COLLABORATOR
GRANT | PROGRESS | STATUS |
---|---|---|
Deep Learning In Molecular Descriptors Mining And Optimization For Drug-potentials Targeting G Protein-coupled Receptors
Researcher(s) : Prof. Dr. Vannajan Sanghiran Lee, Dr. Heh Choon Han, Dr. Saw Shier Nee, Dr. Nurul Binti Japar, Assoc. Prof. Ts. Ir. Dr. Mohammad Lutfi Othman, - |
|
on going |
SATREPS : The Trilateral Collaboration Project for Anti-infectious Disease Drug Development: From Lead Optimization to Preclinical Testing
Researcher(s) : Associate Prof. Dr. Choo Yeun Mun, Associate Prof. Dr. Rozana Binti Othman, Associate Prof. Dr. Shatrah Binti Othman, Prof. Dr. Vannajan Sanghiran Lee, Dr. Iskandar Bin Abdullah, Dr. Lee Yean Kee, Associate Prof. Dr. Nurshamimi Bte Nor Rashid, Dr. Abdullah Al-hadi Bin Ahmad Fuaad, Dr. Heh Choon Han |
|
on going |
Investigating Factors Affecting Aptamer?s Conformation And Target Sensitivity At The Aptamer-graphene Interface And Mechanism Description For Biosensing Applications
Researcher(s) : Dr. Chin Sek Peng, Prof. Dr. Thong Kwai Lin, Dr. Heh Choon Han, Dr. Subhashini A/p Raj Kumal |
|
on going |
Pharmaceutical Excipient Development: Converting Sago Starch As A Direct Compression Tablet Excipient
Researcher(s) : Dr. Heh Choon Han, M. Mothilal |
|
end |
Interdisciplinary And Target-based Development Of Nutraceuticals And Drugs For Prevention And Treatments Of Diseases
Researcher(s) : Dr. Heh Choon Han, Dr. Chee Chin Fei |
|
end |
Investigations Into The Poor Neutralization Efficacy Of Cobra Antivenom Against Lethal Cobra Neurotoxins Through In Vitro, In Vivo And In Silico Studies
Researcher(s) : Prof. Dr. Tan Nget Hong, Associate Prof. Dr. Tan Choo Hock, Dr. Heh Choon Han, Dr. Ng Tzu Shan |
|
end |
Understanding Release Characteristics And Pharmacokinetics Study Of Encapsulated Nanoparticle Gel Transdermal Delivery Of Testosterone
Researcher(s) : Dr. Heh Choon Han, Prof. Dr. Zamri Bin Chik |
|
end |
Unravelling The Antineoplastic Mechanism Of Anilinoquinazoline Compound In Lung Cancer Stem Cells And Zebrafish
|
|
end |
Multiscale Refinement Of Cryo-electron Microscopy Data For Structural Analysis And Mechanism Study Of Biological Macromolecules
|
|
end |
Virtual Screening Of Peptide-cell Membrane
Researcher(s) : Dr. Heh Choon Han |
|
end |