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DR. HEH CHOON HAN

Department of Pharmaceutical Chemistry

Faculty of Pharmacy

silverbotum.edu.my
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Biography

Interested in computer-aided drug discovery. Developed Self-Evolving Peptide Algorithm (SEPA) for the better virtual screening of potential peptides towards specific drug target. SEPA is available here:

https://drive.google.com/drive/folders/1aEmCaSIkXdEJcAX8X1qPNJrzhBGSKv7p

or

https://github.com/RyanHeh/SEPA

 


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Annual Publications by Category
Summary of Budget vs Expenditure per vote for all research grants
Last 3 Projects
Project Title Progress Status
A Mechanistic Study To Identify The Upstream Therapeutic Target Of Tribenzyltin Carboxylates For Improving Cancer Chemotherapy
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In Silico Self-evolving Peptides Algorithm For The Discovery Of Potential Peptide Inhibitor Against Alpha-amylase And Alpha-glucosidase
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Latest Publications
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2026

Multifaceted anticancer mechanisms of tribenzyltin carboxylates: DNA minor groove targeting and inhibition of key enzymes in DNA replication, nucleotide synthesis, and redox homeostasis

2026

Selective Stabilization of LRRK2 Kinase Conformations Reveals Distinct Modes of Action for Type I and II Inhibitors

2025

Exploring the Impact of LRRK2 WD40 G2294R Mutation on Conformation and Dimerisation Dynamics: Insights From Molecular Dynamics Simulation

2025

Comparative Molecular Dynamics Reveals How LRRK2 Inhibitors Distinguish G2019S from Wild-Type

2016

Rational Drug Discovery: Virtual Screening of DEN-2 Non-competitive Inhibitors.