ARTICLE IN ACADEMIC JOURNALS
| NO | DETAILS OF ARTICLE IN ACADEMIC JOURNALS |
|---|---|
| 1. |
<i>Candida auris</i> adhesins, specifically Als3, a key target to understand and mitigate
2025
Author(s) : Najihah Binti Mohd Hashim, Chin Sek Peng Source :
MYCOLOGIA
DOI :
10.1080/00275514.2025.2536345
|
| 2. |
Comparative Molecular Dynamics Reveals How LRRK2 Inhibitors Distinguish G2019S from Wild-Type
2025
Source :
NEUROCHEMICAL RESEARCH
DOI :
10.1007/s11064-025-04520-w
|
| 3. |
Selective Stabilization of LRRK2 Kinase Conformations Reveals Distinct Modes of Action for Type I and II Inhibitors
2025
Author(s) : Heh Choon Han, Chin Sek Peng Source :
CELL BIOCHEMISTRY AND BIOPHYSICS
DOI :
10.1007/s12013-025-01877-1
|
| 4. |
Indolenine-substituted pyrazole derivative 4e inhibits planktonic <i>Staphylococcus lugdunensis</i> growth and biofilm formation by disrupting purine biosynthesis and compromising cell wall and membrane integrity
2025
Source :
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
DOI :
10.1128/aac.00199-25
|
| 5. |
Exploring the Impact of LRRK2 WD40 G2294R Mutation on Conformation and Dimerisation Dynamics: Insights From Molecular Dynamics Simulation
2025
Author(s) : Heh Choon Han, Chin Sek Peng Source :
JOURNAL OF CELLULAR BIOCHEMISTRY
DOI :
10.1002/jcb.70011
|
| 6. |
PDADMAC/Alginate-Coated Gold Nanorod For Eradication of Staphylococcus Aureus Biofilms
2024
Author(s) : Chung Lip Yong, Misni Bin Misran, Chee Chin Fei, Tay Sun Tee, Kiew Lik Voon, Teo Yin Yin, Leo Bey Fen, Chin Sek Peng, Muhammad Farid Nazer Bin Muhammad Faruqu Source :
INTERNATIONAL JOURNAL OF NANOMEDICINE
DOI :
10.2147/IJN.S452085
|
| 7. |
Synthesis and<i> Staphylococcus</i><i> aureus</i> biofilm inhibitory activity of indolenine-substituted pyrazole and pyrimido[1,2-<i>b</i>]indazole derivatives
2023
Source :
BIOORGANIC & MEDICINAL CHEMISTRY
DOI :
10.1016/j.bmc.2023.117485
|
| 8. |
Surgical site infection and development of antimicrobial sutures: a review
2022
Source :
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
|
| 9. |
Automated in silico EGFR Peptide Inhibitor Elongation using Self-evolving Peptide Algorithm
2022
Author(s) : Heh Choon Han, Chin Sek Peng Source :
CURRENT COMPUTER-AIDED DRUG DESIGN
DOI :
10.2174/1573409918666220516144300
|
| 10. |
Protein-Protein Interactions: Insight from Molecular Dynamics Simulations and Nanoparticle Tracking Analysis
2021
Source :
MOLECULES
DOI :
10.3390/molecules26185696
|
| 11. |
Discovery of Dengue Virus Inhibitors
2020
Author(s) : Rohana Binti Yusof, Noorsaadah Binti Abd Rahman, Rozana Binti Othman, Shatrah Binti Othman, Vannajan Sanghiran Lee, Heh Choon Han, Chin Sek Peng Source :
CURRENT MEDICINAL CHEMISTRY
DOI :
10.2174/0929867326666181204155336
|
| 12. |
In vitro functional evaluation of isolaureline, dicentrine and glaucine enantiomers at 5-HT2 and alpha(1) receptors
2019
Author(s) : Chung Lip Yong, Noorsaadah Binti Abd Rahman, Michael James Christopher Buckle, Chee Chin Fei, Tee Jia Ti, Ian Charles Paterson, Chin Sek Peng Source :
CHEMICAL BIOLOGY DRUG DESIGN
|
| 13. |
Loop dynamics behind the affinity of DARPins towards ERK2: Molecular dynamics simulations (MDs) and elastic network model (ENM)
2019
Author(s) : Noorsaadah Binti Abd Rahman, Sharifuddin Bin Md Zain, Vannajan Sanghiran Lee, Chin Sek Peng Source :
JOURNAL OF MOLECULAR LIQUIDS
|
| 14. |
Dynamics and binding interactions of peptide inhibitors of dengue virus entry
2019
Author(s) : Noorsaadah Binti Abd Rahman, Sharifuddin Bin Md Zain, Vannajan Sanghiran Lee, Chin Sek Peng Source :
JOURNAL OF BIOLOGICAL PHYSICS
|
| 15. |
In vitro functional evaluation of isolaureline, dicentrine and glaucine enantiomers at 5-HT2 and alpha1 receptors
2018
Author(s) : Chin Sek Peng Source :
Chem Biol Drug Des
DOI :
10.1111/cbdd.13390
|
| 16. |
Synthesis and evaluation of nuciferine and roemerine enantiomers as 5-HT2 and α1 receptor antagonists
2018
Author(s) : Chin Sek Peng Source :
MedChemComm
DOI :
10.1039/C7MD00629B
|
| 17. |
In silico study on anti- Chikungunya virus activity of hesperetin
2016
Author(s) : Chin Sek Peng Source :
PeerJ
|
| 18. |
In Silico and In Vitro Analysis of Bacoside A Aglycones and its Derivatives as the Constituents Responsible for the Cognitive Effects of Bacopa monnieri
2015
Author(s) : Chin Sek Peng Source :
PLos One
|
| 19. |
Flavonoids with M1 muscarinic acetylcholine receptor binding activity.
2014
Author(s) : Chin Sek Peng Source :
Molecules
|
| 20. |
Toward activated homology models of the human M1 muscarinic acetylcholine receptor.
2014
Author(s) : Chin Sek Peng Source :
Journal of Molecular Graphics and Modelling
|
| 21. |
Thermo-effects of methionine aminopeptidase: Molecular dynamics studies
2007
Author(s) : Chin Sek Peng Source :
World Congress on Medical Physics and Biomedical Engineering
|
RESEARCH PROJECT
| GRANT | PROGRESS | STATUS |
|---|---|---|
|
Decoding Chaga?s Potential: Integrated Bioinformatics, Molecular Modelling, and In Vitro Validation of Inonotus obliquus for Breast Cancer Therapeutics
|
|
new |
|
Interdisciplinary And Target-based Development Of Nutraceuticals And Drugs For Prevention And Treatments Of Diseases
Researcher(s) : Dr. Heh Choon Han, Dr. Chee Chin Fei |
|
end |
|
Design And Development Of Antimicrobial Molecules/anti-virulence Agents For Suppression Of Biofilm Formation Of Staphylococcus Aureus
|
|
end |
RESEARCH COLLABORATOR
| GRANT | PROGRESS | STATUS |
|---|---|---|
|
Investigating Factors Affecting Aptamer?s Conformation And Target Sensitivity At The Aptamer-graphene Interface And Mechanism Description For Biosensing Applications
Researcher(s) : Dr. Chin Sek Peng, Prof. Dr. Thong Kwai Lin, Dr. Heh Choon Han, Dr. Subhashini A/p Raj Kumal |
|
on going |
|
Wp2: Development Of Novel Therapeutic Agent And Delivery Method For Lung Cancer
Researcher(s) : Prof. Dr. Azhar Bin Ariffin, Dr. Chin Sek Peng, Dr. Leong Kok Hoong, Dr. Leong Sze Wei |
|
end |
|
Understanding The Mechanism Of Extracellular Release Of ?-synuclein Through Leucine-rich Repeat Kinase 2 (lrrk2) Mutations And Kinase Inhibition
Researcher(s) : Prof. Dr. Lim Shen-yang, Dr. Chee Chin Fei, Prof. Dr. Tan Ai Huey, Dr. Chin Sek Peng |
|
end |
|
In Silico Self-evolving Peptides Algorithm For The Discovery Of Potential Peptide Inhibitor Against Alpha-amylase And Alpha-glucosidase
|
|
end |
|
Development Of Highly Potent, Selective, And Brain-penetrant Aminopyridoxamine Leucine-rich Repeat Kinase 2 (lrrk2) Inhibitors For Parkinson S Disease Treatment
|
|
end |
|
Development Of Highly Potent, Selective, And Brain-penetrant Aminopyridoxamine Leucine-rich Repeat Kinase 2 (lrrk2) Inhibitors For Parkinson S Disease Treatment
|
|
end |