ASSOCIATE PROF. DR. CHEN YENG
Department of Oral and Craniofacial Sciences
Faculty of Dentistry
chenyengum.edu.myView CV | |
Publons | |
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Biography | |
Associate Professor Dr. Chen Yeng is an expert in cancer biomarker discovery, biosensor development, and natural therapeutics, with a multidisciplinary approach that bridges nanotechnology, molecular biology, and biomedicine. Her expertise is particularly evident in her work on innovative diagnostic technologies and personalized therapeutic solutions, targeting both cancer and infectious diseases. Her research interests span several cutting-edge areas. One of her primary focuses is the identification and characterization of cancer biomarkers, particularly through novel approaches targeting at immunogenic host proteins. This line of research explores how immunogenic proteins’ interventions might modulate cancer risk, representing an innovative intersection of microbiology, proteomics, and oncology. Dr. Chen is also deeply engaged in developing advanced diagnostic tools, including nanobiosensors with enhanced sensitivity and specificity. These devices, designed to detect critical biomarkers such as those associated with tuberculosis, blood clotting disorders, and oral cancer, are transformative for early disease detection. Her work in biosensors, utilizing materials like gold nanoparticles and zinc oxide nanolayers, has set new standards in diagnostic accuracy and reliability. Another cornerstone of her research is the study of natural plant extracts for therapeutic applications, particularly in cancer treatment. She investigates the biochemical and pharmacological properties of these extracts, focusing on their mechanisms of action, such as inducing apoptosis, causing cell cycle arrest, and promoting mitochondrial dysfunction in cancer cells. Her exploration of natural products' roles in modulating microRNAs further highlights her innovative approach to cancer research. Dr. Chen’s expertise also extends to the antioxidant, hepatoprotective, and genoprotective properties of herbal compounds, offering potential preventive and therapeutic solutions for chronic diseases. These studies underline her commitment to sustainable and natural approaches in healthcare. Her contributions to genomics and proteomics, particularly in large-scale screening for biological markers, further demonstrate her role as a leader in translating complex biological data into meaningful clinical applications. By combining her deep understanding of molecular biology with a focus on real-world impact, Dr. Chen has established herself as a pioneer in her field. Dr. Chen’s academic influence is demonstrated by her impressive h-index of 27 (ResearchID) and 38 (Scopus), with over 4,000 citations to her name. Her extensive publication record spans high-impact journals, contributing significantly to advancements in dentistry, oncology, and biomedical engineering. She is recognized as a top scientist in Malaysia, ranking among the leading figures in dentistry according to the AD Scientific Index. As a respected peer reviewer for prestigious journals, including Coordination Chemistry Reviews, Periodontal 2000, Biosensors and Bioelectronics, and Cancer Letters, Dr. Chen plays a critical role in maintaining the quality of research within her fields of expertise. Her contributions extend to academic leadership, where she had supervised and graduated over 20 postgraduate students, including 11 PhD candidates, nurturing the next generation of scientific leaders. Her leadership in dental education accreditation has further solidified her impact on academic excellence. She has played pivotal roles in the reaccreditation of dental programs at the University of Malaya and other institutions, ensuring that these programs meet global standards. Through her commitment to interdisciplinary collaboration, Dr. Chen has partnered with industry leaders to translate research findings into practical healthcare solutions, such as rapid diagnostic tools and personalized treatments. These collaborations exemplify her ability to bridge scientific discovery with real-world applications. In summary, Dr. Chen’s expertise and research interests reflect a holistic approach to biomedical science, integrating cutting-edge technologies with sustainable practices. Her work not only pushes the boundaries of knowledge in cancer research and diagnostics but also has the potential to transform patient care and public health globally. |
Publication
Finance
Project Title | Progress | Status |
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Identification of Glycosylated Proteins Expression Pattern in Oral Squamous Cell Carcinoma |
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This information is generated from Research Grant Management System |
Selective detection of alpha synuclein amyloid fibrils by faradaic and non-faradaic electrochemical impedance spectroscopic approaches
Selective detection of alpha synuclein amyloid fibrils by faradaic and non-faradaic electrochemical impedance spectroscopic approaches
Plant bioactive compounds driven microRNAs (miRNAs): A potential source and novel strategy targeting gene and cancer therapeutics
RNA-sequencing exploration on SIR2 and SOD genes in Polyalthia longifolia leaf methanolic extracts (PLME) mediated anti-aging effects in Saccharomyces cerevisiae BY611 yeast cells
Surface Engineered Nanobiosensor for Disease Biomarker Identification
Purification of herbal biomolecules
The Role of Phytochemicals in Cancer Prevention and Cure
The Role of Phytochemicals in Cancer Prevention and Cure