Associate Professor Dr. Chen Yeng is a senior researcher in University of Malaya, Kuala Lumpur, Malaysia. She received her PhD in 2007 from Medical Faculty, University of Malaya. She started her career as a lecturer in Monash University Malaysia in the year 2007 and further pursed her carrier as a senior lecturer and laboratory coordinator in Institute for Research in Molecular Medicine (INFORMM), University Sains Malaysia in the year 2008. She subsequently returned to University of Malaya in 2010 as an Associate Professor at the Department of Oral Biology and Biomedical Science, Faculty of Dentistry in University of Malaya, Kuala Lumpur, Malaysia. She is a member of the Malaysian Society of Parasitology and Tropical Medicine (since 2007), Infectious Disease Cluster, AMDI (since 2010), High Impact Research Committee (since 2013) and American Chemical Society (since 2013). She was also an invited speaker to various seminar/workshop including in Gene Cloning Workshop, INFORMM, USM. Chen Yeng has a track record of around 100 publications in renowned peer-reviewed scientific journals (Journal of Hematology & Oncology, Current Gene Therapy, Biosensors & Bioelectronics, PlosOne, BMC., etc) including publications in books and patents. She is an Editorial Board Member and Reviewer of a number of international journals (including BioMed Central Journals, Phytomedicine, Biosensors & Bioelectronics, Scientific Reports, Oral Disease etc). Chen Yeng's research of interest spans around Proteomics and Immunoproteomics studies in various Infectious and Non- Infectious Disease. She is currently pursuing to expand her interest of study on Cancer Genetics and Aptamer based therapies.
She mainly works on biomarker discovery and designing/developing biosensors to screen and validate the biomarkers of different diseases. For biomarkers discovery, different -omics platforms (proteomics, metabolomic and genomics) are used. From discovery, large scale screening follows using a self- developed biosensor to validate the data. Besides, she collaborates on research in Herbalism including Herbology, Herbal Medicine, Phytomedicine, Phytotherapy, and Phytopharmacology.
Area of expertise
1) Use of high-throughput proteomics for discovery of biomarkers in infectious (Malaria, toxoplasmosis) and non-infectious disease (cancers).
2) Development of Biosensors which can efficiently produce large amounts of testing data for genomic and proteomic studies.
3) Finding therapeutic benefits through screening of natural compounds (plant- sourced) and development of therapeutic agents from herbal medicine.
1) Identification and discovery of novel biomarkers using high-throughput proteomics techniques across a wide variety of platforms, including gel-based proteomics, mass spectrometry (MS) and protein microarrays. Quantitative profiling to understand proteome alterations along with comprehensive autoantibody profiling of serum, urine and CSF samples.
2) Research focus on various neglected tropical diseases eg malaria, toxoplasmosis etc. Additionally, multi-dimensional Omics data are employed for the in-silico studies and models. She collaborates actively both nationally and internationally to advance knowledge in this frontier for the benefit of global health. Her vision is to enhance clinical proteomics research and bring innovation in biotechnology and global life sciences R&D.