Curriculum Vitae

ASSOCIATE PROF. DR. CHEN YENG

Associate Professor
  • Department of Oral and Craniofacial Sciences
    Faculty of Dentistry
  • chenyeng
  • +603-79676470

BIOGRAPHY

Associate Professor Dr. Chen Yeng is an expert in cancer biomarker discovery, biosensor development, and natural therapeutics, with a multidisciplinary approach that bridges nanotechnology, molecular biology, and biomedicine. Her expertise is particularly evident in her work on innovative diagnostic technologies and personalized therapeutic solutions, targeting both cancer and infectious diseases. Her research interests span several cutting-edge areas. One of her primary focuses is the identification and characterization of cancer biomarkers, particularly through novel approaches targeting at immunogenic host proteins. This line of research explores how immunogenic proteins’ interventions might modulate cancer risk, representing an innovative intersection of microbiology, proteomics, and oncology. Dr. Chen is also deeply engaged in developing advanced diagnostic tools, including nanobiosensors with enhanced sensitivity and specificity. These devices, designed to detect critical biomarkers such as those associated with tuberculosis, blood clotting disorders, and oral cancer, are transformative for early disease detection. Her work in biosensors, utilizing materials like gold nanoparticles and zinc oxide nanolayers, has set new standards in diagnostic accuracy and reliability. Another cornerstone of her research is the study of natural plant extracts for therapeutic applications, particularly in cancer treatment. She investigates the biochemical and pharmacological properties of these extracts, focusing on their mechanisms of action, such as inducing apoptosis, causing cell cycle arrest, and promoting mitochondrial dysfunction in cancer cells. Her exploration of natural products' roles in modulating microRNAs further highlights her innovative approach to cancer research. Dr. Chen’s expertise also extends to the antioxidant, hepatoprotective, and genoprotective properties of herbal compounds, offering potential preventive and therapeutic solutions for chronic diseases. These studies underline her commitment to sustainable and natural approaches in healthcare. Her contributions to genomics and proteomics, particularly in large-scale screening for biological markers, further demonstrate her role as a leader in translating complex biological data into meaningful clinical applications. By combining her deep understanding of molecular biology with a focus on real-world impact, Dr. Chen has established herself as a pioneer in her field. Dr. Chen’s academic influence is demonstrated by her impressive h-index of 28 (ResearchID) and 39 (Scopus), with over 4,500 citations to her name. Her extensive publication record spans high-impact journals, contributing significantly to advancements in dentistry, oncology, and biomedical engineering. She is recognized as a top scientist in Malaysia, ranking among the leading figures in dentistry according to the AD Scientific Index.As a respected peer reviewer for prestigious journals, including Coordination Chemistry Reviews, Periodontal 2000, Biosensors and Bioelectronics, and Cancer Letters, Dr. Chen plays a critical role in maintaining the quality of research within her fields of expertise. Her contributions extend to academic leadership, where she had supervised and graduated over 20 postgraduate students, including 12 PhD candidates, nurturing the next generation of scientific leaders.Her leadership in dental education accreditation has further solidified her impact on academic excellence. She has played pivotal roles in the reaccreditation of dental programs at the University of Malaya and other institutions, ensuring that these programs meet global standards.Through her commitment to interdisciplinary collaboration, Dr. Chen has partnered with industry leaders to translate research findings into practical healthcare solutions, such as rapid diagnostic tools and personalized treatments. These collaborations exemplify her ability to bridge scientific discovery with real-world applications.In summary, Dr. Chen’s expertise and research interests reflect a holistic approach to biomedical science, integrating cutting-edge technologies with sustainable practices. Her work not only pushes the boundaries of knowledge in cancer research and diagnostics but also has the potential to transform patient care and public health globally.

 

AREAS OF EXPERTISE

  • BIOMARKERS
    Medical And Health Sciences, Health Sciences, Biomedical Sciences
  • DEVELOPMENT OF TRADITIONAL AND HERBAL MEDICINE (INCLUDING TRADITIONAL MEDICINE AND NATURAL PRODUCT)
    Medical And Health Sciences, Specialist Topics In Medical And Health Sciences, Traditional And Complementary Medicine
  • PROTEOMICS IN BIOTECHNOLOGY (INCLUDING PEPTIDES)
    Applied Science And Technology, Biotechnology, Molecular Biology
  • BIOSENSOR MATERIALS
    Applied Science And Technology, Material Sciences And Technology Including Engineering Materials, Sensor Materials

ACADEMIC QUALIFICATION

  • PhD, (Immunoproteomics)
    Universiti Malaya (UM)
  • MMedSc, (Sains Bioperubatan)
    Universiti Malaya (UM)
  • BSc (Hons)(Chemistry), (Biochemistry)
    Universiti Malaya (UM)

WORKING EXPERIENCE

  • 01 Aug 2008 -
    01 Aug 2011-
    Pensyarah Kanan Gred Ds51 (Tetap)
    Universiti Sains Malaysia
  • 15 Nov 2007 -
    01 Aug 2008-
    Pensyarah
    Universiti Sains Malaysia

ADMINISTRATIVE DUTIES

  • Lab Coordinator for Craniofacial and Molecular Biology Laboratory
    01 Nov 2011 - present (Department of Oral and Craniofacial Sciences, Faculty of Dentistry)
  • Assessor for Elective Project 2013/2014
    08 Feb 2014 - present (Department of Oral and Craniofacial Sciences, Faculty of Dentistry)
  • Master in Dental Sciences
    31 Aug 2022 - 31 Aug 2024 (Department of Oral and Craniofacial Sciences, Faculty of Dentistry)
  • Penyelaras Kurikulum bagi program BDS
    28 Jul 2023 - 27 Jul 2024 (Department of Oral and Craniofacial Sciences, Faculty of Dentistry)
  • LANTIKAN SEBAGAI PANEL PENILAI AKREDITASI PROGRAM DOKTOR FALSAFAH DAN SARJANA SAINS PERGIGIAN DARI FAKULTI PERGIGIAN, UKM
    24 Jun 2024 - 25 Jun 2024 (National)
  • Chairperson of 15th National Dental Scientific Conference
    17 Jun 2023 - 17 Jun 2023 (National)
  • Coordinator
    09 Nov 2021 - 31 Aug 2022 (Department of Oral and Craniofacial Sciences, Faculty of Dentistry)
  • Committee Members
    19 Jul 2021 - 19 Jul 2022 (Department of Oral and Craniofacial Sciences, Faculty of Dentistry)
  • Committee Members
    07 Jun 2022 - 13 Jun 2022 (Department of Oral and Craniofacial Sciences, Faculty of Dentistry)
  • Acting Head of Department
    05 May 2022 - 06 May 2022 (Department)
  • Coordinator
    19 Jul 2021 - 31 Dec 2021 (Department of Oral and Craniofacial Sciences, Faculty of Dentistry)
  • University Malaya Representative
    01 Jan 2021 - 31 Dec 2021 (International)
  • Programme Coordinator
    01 Apr 2020 - 31 Dec 2021 (University Malaya)
  • Chief Auditor
    01 Jan 2020 - 31 Dec 2021 (Faculty)
  • Organizing committee
    11 Nov 2020 - 31 Dec 2021 (International)
  • Programme Coordinator
    01 Oct 2019 - 01 Oct 2020 (University Malaya)
  • Programme Coordinator
    01 Oct 2019 - 01 Oct 2020 (University Malaya)
  • Programme Coordinator
    01 Oct 2019 - 01 Oct 2020 (University Malaya)
  • Programme Coordinator
    01 Oct 2019 - 01 Oct 2020 (University Malaya)
  • Interviewer
    02 Jun 2020 - 10 Jun 2020 (Faculty)
  • Chief Invigilator
    08 Jan 2020 - 08 Jan 2020 (University Malaya)
  • Chief Invigilator
    02 Jan 2019 - 02 Jan 2019 (University Malaya)
  • Conference Committee Member (Deputy Head)
    01 Mar 2017 - 02 Mar 2017 (Department of Oral and Craniofacial Sciences, Faculty of Dentistry)
  • Auditor
    06 Apr 2015 - 05 Jul 2015 (Faculty)
  • Internal ISO Auditor for University of Malaya
    22 Mar 2013 - 23 Mar 2015 (University Malaya)
  • Sub Committee Member (Scientific Program) 14th Dental Student Scientific Conference
    27 Feb 2013 - 28 Feb 2014 (Department of Oral and Craniofacial Sciences, Faculty of Dentistry)

MEMBERSHIPS

  • KEAHLIAN PERSEKUTU MAJLIS PROFESSOR NEGARA, MEMBER
    Since 2022 (National)
  • LIFETIME MEMBER 1-2018-040, MEMBER
    Since 2021 (International)
  • INTERNATIONAL CONFERENCE ON DRUG DISCOVERY ANDTRANSLATIONALMEDICINE2021(ICDDTM'21), ADVISORY BOARD
    Since 2019 (International)
  • MALAYSIAN ASSOCIATION FOR CANCER RESEARCH (MACR) PPM-005-10-18102017, ACADEMIC MEMBER
    Since 2018 (National)
  • MALAYSIAN ASSOCIATION FOR CANCER RESEARCH (MACR), MEMBERSHIP
    Since 2018 (National)
  • LIFETIME MEMBERSHIP , MEMBER
    Since 2018 (National)
  • ORAL HEALTH AND DENTAL STUDIES, EDITORIAL BOARD
    Since 2017 (International)
  • DENTAL RESEARCH AND MANAGEMENT, EDITORIAL BOARD
    Since 2016 (International)
  • HIGH IMPACT RESEARCH COMMITEE, MEMBER
    Since 2013 (University)
  • ORAL CANCER AND RESEARCH COORDINATING CENTER, MEMBER
    Since 2012 (University)
  • INFECTIOUS DISEASES CLUSTER (IDC), ADVANCED MEDICAL & DENTAL INSTITUTE, ASSOCIATE MEMBER
    Since 2010 (National)
  • MALAYSIAN SOCIETY OF PARASITOLOGY AND TROPICAL MEDICINE , MEMBER
    Since 2007 (National)
  • MEMBER, MEMBER
    2021 to 2022 (International)
  • MALAYSIAN SOCIETY OF PARASITOLOGY AND TROPICAL MEDICINE (MSPTM) , MEMBER
    2017 to 2022 (National)
  • MENYDIAKAN BUKU PANDUAN PHD PROGRAMME, COMMITTEE MEMBER
    2021 to 2021 (University)
  • MENYEDIAKAN BUKU PANDUAN FOR MASTER PROGRAMME , COMMITTEE MEMBER
    2021 to 2021 (University)
  • ICOIOM 2018 ADVISORY BOARD, FACULTY OF DENTISTRY, UM, ADVISORY BOARD
    2018 to 2018 (University)
  • AMERICAN CHEMICAL SOCIETY, NOMINATED MEMBER
    2013 to 2016 (International)

AWARD AND STEWARDSHIP

  • Expert Panel in Rapid-Review: Covid-19 (a Overlay Journal That is a Collaboration Between Uc Berkeley and The Mit Press).
    2020, UC Berkeley and the MIT Press,  (International)
  • Judge for 3rd Icom 2020 and 13th Postgraduate E-Conference
    2020, University of Malaya,  (International)
  • First Place Poster Presentation in The 20th University of Malaya Dental Undergraduate Scientific Conference
    2019, University of Malaya,  (University)
  • The Top 10% Most Cited Plos One Papers (Published in 2016)
    2019, Joerg Heber, Editor-in-Chief, PLOS ONE ORCID: 0000-0002-6370-4254,  (International)
  • First Price Winners of Icoiom 2018 (Oral Presentation)
    2018, The International Conference On Oral Immunology & Oral Microbiology (ICOIOM) ,  (International)
  • Meneghetti Award to Dr. Ting Choo Yuen
    2017, Antonio Meneghetti Scientific and Humanistic Research Foundation,  (International)

PUBLICATIONS

Article in Journal
WoS
  1. Adam, Hussaini; Gopinath, Subash C. B.; Krishnan, Hemavathi; Adam, Tijjani; Fakhri, Makram A.; Salim, Evan T.; Shamsher, A.; Subramaniam, Sreeramanan; Chen, Yeng (2025). Selective detection of alpha synuclein amyloid fibrils by faradaic and non-faradaic electrochemical impedance spectroscopic approaches, BIOELECTROCHEMISTRY. 161. doi:10.1016/j.bioelechem.2024.108800
  2. Lim, Jia-Chun; Gopinath, Subash C. B.; Tan, Sing-Mei; Chow, Emily M. Y.; Chen, Yeng (2025). Augmented sensitivity in electrolyte determination for sweat analysis: Rapid amperometric quantification by self-induced gold nanorods aggregation, JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS. 168. doi:10.1016/j.jtice.2024.105919
  3. Hemagirri, Manisekaran; Chen, Yeng; Gopinath, Subash C. B.; Adnan, Mohd; Patel, Mitesh; Sasidharan, Sreenivasan (2024). RNA-sequencing exploration on SIR2 and SOD genes in Polyalthia longifolia leaf methanolic extracts (PLME) mediated anti-aging effects in Saccharomyces cerevisiae BY611 yeast cells, BIOGERONTOLOGY. 25(4), 705-737. doi:10.1007/s10522-024-10104-y
  4. Huda, Hisham-Sultan-Alkatib; Majid, Nazia Binti Abdul; Chen, Yeng; Adnan, Mohd; Ashraf, Syed Amir; Roszko, Marek; Bryla, Marcin; Kieliszek, Marek; Sasidharan, Sreenivasan (2024). Exploring the ancient roots and modern global brews of tea and herbal beverages: A comprehensive review of origins, types, health benefits, market dynamics, and future trends, FOOD SCIENCE & NUTRITION. . doi:10.1002/fsn3.4346
  5. Niu, Jiaojiao; Chen, Yeng; Chai, Hwa Chia; Sasidharan, Sreenivasan (2024). Exploring MiR-484 Regulation by Polyalthia longifolia: A Promising Biomarker and Therapeutic Target in Cervical Cancer through Integrated Bioinformatics and an In Vitro Analysis, BIOMEDICINES. 12(4). doi:10.3390/biomedicines12040909
  6. Teow, Jun Yao; Zhang, Qinyi; Abidin, Syafiq Asnawi Zainal; Tan, Chuey Chuan; Rahman, Syarifah Nur Syed Abdul; Karsani, Saiful Anuar; Othman, Iekhsan; Chen, Yeng; Lakshmipriya, Thangavel; Gopinath, Subash C. B. (2024). Pioneering biosensor approaches for oral squamous cell carcinoma diagnosis: A comprehensive review, PROCESS BIOCHEMISTRY. 141, 71-81. doi:10.1016/j.procbio.2024.02.015
  7. Adam, Hussaini; Gopinath, Subash C. B.; Arshad, M. K. Md; Adam, Tijjani; Hashim, Uda; Sauli, Zaliman; Fakhri, Makram A.; Subramaniam, Sreeramanan; Chen, Yeng; Sasidharan, Sreenivasan; Wu, Yuan Seng (2023). Integration of microfluidic channel on electrochemical-based nanobiosensors for monoplex and multiplex analyses: An overview, JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS. 146. doi:10.1016/j.jtice.2023.104814
  8. Adam, Hussaini; Gopinath, Subash C. B.; Kumarevel, Thirumananseri; Arshad, M. K. Md; Adam, Tijjani; Sauli, Zaliman; Subramaniam, Sreeramanan; Hashim, Uda; Chen, Yeng (2023). Selective detection of amyloid fibrils by a dipole moment mechanism on dielectrode-Structural insights by in silico analysis, PROCESS BIOCHEMISTRY. 126, 23-32. doi:10.1016/j.procbio.2022.12.030
  9. Hui, Hu; Gopinath, Subash C. B.; Ismail, Zool H.; Chen, Yeng; Pandian, K.; Velusamy, Palaniyandi (2023). Cardiovascular biomarker troponin I biosensor: Aptamer-gold-antibody hybrid on a metal oxide surface, BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY. . doi:10.1002/bab.2380
  10. Jing, Hong Hui; Bardakci, Fevzi; Akgol, Sinan; Kusat, Kevser; Adnan, Mohd; Alam, Mohammad Jahoor; Gupta, Reena; Sahreen, Sumaira; Chen, Yeng; Gopinath, Subash C. B.; Sasidharan, Sreenivasan (2023). Green Carbon Dots: Synthesis, Characterization, Properties and Biomedical Applications, JOURNAL OF FUNCTIONAL BIOMATERIALS. 14(1). doi:10.3390/jfb14010027
  11. Qin, Dapeng; Gong, Qiuping; Li, Xin; Gao, Yanping; Gopinath, Subash C. B.; Chen, Yeng; Yang, Zehua (2023). Identification of Mycoplasma pneumoniae by DNA-modified gold nanomaterials in a colorimetric assay, BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY. 70(2), 553-559. doi:10.1002/bab.2377
  12. Ranjutha, Valiappan; Chen, Yeng; Al-Keridis, Lamya Ahmed; Patel, Mitesh; Alshammari, Nawaf; Adnan, Mohd; Sahreen, Sumaira; Gopinath, Subash C. B.; Sasidharan, Sreenivasan (2023). Synergistic Antimicrobial Activity of Ceftriaxone and Polyalthia longifolia Methanol (MEPL) Leaf Extract against Methicillin-Resistant Staphylococcus aureus and Modulation of mecA Gene Presence, ANTIBIOTICS-BASEL. 12(3). doi:10.3390/antibiotics12030477
  13. Tan, Wan Yuen; Gopinath, Subash C. B.; Anbu, Periasamy; Yaakub, Ahmad Radi Wan; Subramaniam, Sreeramanan; Chen, Yeng; Sasidharan, Sreenivasan (2023). Bio-Enzyme Hybrid with Nanomaterials: A Potential Cargo as Sustainable Biocatalyst, SUSTAINABILITY. 15(9). doi:10.3390/su15097511
  14. Zhang, Qinyi; Teow, Jun Yao; Kerishnan, Jesinda Pauline; Abd Halim, Adyani Azizah; Chen, Yeng (2023). Clusterin and Its Isoforms in Oral Squamous Cell Carcinoma and Their Potential as Biomarkers: A Comprehensive Review, BIOMEDICINES. 11(5). doi:10.3390/biomedicines11051458
  15. Zheng, Kai; Bai, Jiaxiang; Yang, Huilin; Xu, Yaozeng; Pan, Guoqing; Wang, Huaiyu; Geng, Dechun (2023). Nanomaterial-assisted theranosis of bone diseases, BIOACTIVE MATERIALS. 24, 263-312. doi:10.1016/j.bioactmat.2022.12.014
  16. Gao, Ming; Sun, Yuansong; Wang, Qi; Ma, Shuaiting; Guo, Xinwei; Zhou, Lingling; Chen, Yeng; Marimuthu, Kasi; Gopinath, Subash C. B. (2022). Nanosensing colon cancer biomarker on zeolite-modified gap-fingered dielectrodes, BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY. . doi:10.1002/bab.2254
  17. Geng, Huijuan; Gopinath, Subash Cb; Chen, Yeng; Niu, Wenyan (2022). Sensitive Aptasensing of Hepatitis B Viral Antigen Gold Dielectrode by Current-Volt Measurements, JOURNAL OF NANOELECTRONICS AND OPTOELECTRONICS. 17(7), 1011-1018. doi:10.1166/jno.2022.3288
  18. Ma, Renyuan; Gopinath, Subash C. B.; Lakshmipriya, Thangavel; Chen, Yeng (2022). Carbon Material Hybrid Construction on an Aptasensor for Monitoring Surgical Tumors, JOURNAL OF ANALYTICAL METHODS IN CHEMISTRY. 2022. doi:10.1155/2022/9740784
  19. Poh Yan, Leong; Gopinath, Subash C. B.; Subramaniam, Sreeramanan; Chen, Yeng; Velusamy, Palaniyandi; Chinni, Suresh V.; Gobinath, Ramachawolran; Lebaka, Veeranjaneya Reddy (2022). Greener synthesis of nanostructured iron oxide for medical and sustainable agro-environmental benefits, FRONTIERS IN CHEMISTRY. 10. doi:10.3389/fchem.2022.984218
  20. Huang, Y., Zhang, L., Li, Z. Z., Gopinath, S. C. B., Chen, Y., & Xiao, Y. (2021). Aptamer-17 beta-estradiol-antibody sandwich ELISA for determination of gynecological endocrine function. Biotechnology and applied biochemistry, 68(4), 881-888. doi: 10.1002/bab.2008
  21. Jothy, Subramanion L.; Chen, Yeng; Kanwar, Jagat R.; Sasidharan, Sreenivasan (2021). Evaluation of the Genotoxic Potential against H2O2-Radical-Mediated DNA Damage and Acute Oral Toxicity of Standardized Extract of Polyalthia longifolia Leaf (vol 2013, 925380, 2013), EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE. 2021. doi:10.1155/2021/9836793
  22. Wong, Y. L., Anand, R., Yuen, K. M., Mustafa, W. M. W., Abraham, M. T., Tay, K. K., . . . Chen, Y. (2021). Identification of potential glycoprotein biomarkers in oral squamous cell carcinoma using sweet strategies. Glycoconjugate Journal, 38(1), 1-11. doi: 10.1007/s10719-021-09973-z
  23. Wong, Y. L., Ramanathan, A., Yuen, K. M., Mustafa, W. M. W., Abraham, M. T., Tay, K. K., . . . Chen, Y. (2021). Comparative sera proteomics analysis of differentially expressed proteins in oral squamous cell carcinoma. Peerj, 9, 20. doi: 10.7717/peerj.11548
  24. Zhao, J., Chang, W. L., Liu, L., Xing, X. M., Zhang, C., Meng, H. H., . . . Liu, Y. G. (2021). Graphene oxide-gold nanoparticle-aptamer complexed probe for detecting amyloid beta oligomer by ELISA-based immunoassay. Journal of Immunological Methods, 489, 7. doi: 10.1016/j.jim.2020.112942
  25. Hong, X., Hong, X. Y., Zhao, H. M., Chen, C., Gopinath, S. C. B., Lim, D., . . . Yan, G. J. (2020). Improved immunoassay for Insulin-like Growth Factor 1 detection by aminated silica nanoparticle in ELISA. Process Biochemistry, 91, 282-287. doi: 10.1016/j.procbio.2019.12.019
  26. Liu, X. M., Yang, X. Y., Shao, J., Hong, Y. F., Gopinath, S. C. B., Chen, Y., . . . Wang, Y. R. (2020). Coordination of Nanoconjugation with an Antigen/Antibody for Efficient Detection of Gynecological Tumors. Journal of Analytical Methods in Chemistry, 2020, 8. doi: 10.1155/2020/6528572
  27. Su, H. C., Kanchanatip, E., Wang, D. F., Zheng, R. D., Huang, Z. C., Chen, Y., . . . Yan, M. (2020). Production of H-2-rich syngas from gasification of unsorted food waste in supercritical water. Waste Management, 102, 520-527. doi: 10.1016/j.wasman.2019.11.018
  28. Bao, X. C., Huo, G. X., Li, L., Cao, X. B., Liu, Y. M., Lakshmipriya, T., . . . Gopinath, S. C. B. (2019). Coordinated Dispersion and Aggregation of Gold Nanorod in Aptamer-Mediated Gestational Hypertension Analysis. Journal of Analytical Methods in Chemistry, 2019, 10. doi:10.1155/2019/5676159
  29. Kerishnan, J. P., Mah, M. K., Fawzi, N., Ramanathan, A., Lim, G. S., Aziz, A. A., . . . Chen, Y. (2019). The Association between Epstein-Barr virus (EBV) Past Infection with the Risk of Oral Squamous Cell Carcinoma (OSCC). Sains Malaysiana, 48(9), 1969-1974. doi:10.17576/jsm-2019-4809-18
  30. Kirubakari, Balasupramaniam; Shanmugapriya; Sangeetha, Thiagarajan; Vijayarathna, Soundararajan; Chen, Yeng; Kanwar, Jagat R.; Leow, Chiuan Herng; Shin, Lai Ngit; Swamy, Mallappa Kumara; Subramaniam, Sreeramanan; Sasidharan, Sreenivasan (2019). Antibacterial and Antifungal Agents of Higher Plants, NATURAL BIO-ACTIVE COMPOUNDS, VOL 1: PRODUCTION AND APPLICATIONS. , 493-508. doi:10.1007/978-981-13-7154-7_16
  31. Lin, J., Gopinath, S. C. B., Lakshmipriya, T., Chen, Y., Yuan, W. R., Yang, M. (2019). Target DNA detection of human papilloma virus-16 E7 gene by capture-target-reporter sandwich on interdigitated electrode sensor. International Journal of Biological Macromolecules, 141, 564-569. doi: 10.1016/j.ijbiomac.2019.09.012
  32. Wang, H. Q., Lakshmipriya, T., Chen, Y., Gopinath, S. C. B. (2019). Squamous Cell Carcinoma Biomarker Sensing on a Strontium Oxide-Modified Interdigitated Electrode Surface for the Diagnosis of Cervical Cancer. Biomed Research International, 7. doi:10.1155/2019/2807123
  33. Anasdass, Jaculin Raiza; Kannaiyan, Pandian; Raghavachary, Raghunathan; Gopinath, Subash C. B.; Chen, Yeng (2018). Palladium nanoparticle-decorated reduced graphene oxide sheets synthesized using Ficus carica fruit extract: A catalyst for Suzuki cross-coupling reactions, PLOS ONE. 13(2). doi:10.1371/journal.pone.0193281
  34. Kavitha, Nowroji; Vijayarathna, Soundararajan; Shanmugapriya; Oon, Chern Ein; Chen, Yeng; Kanwar, Jagat R.; Punj, Vasu; Sasidharan, Sreenivasan (2018). MicroRNA profiling in MDA-MB-231 human breast cancer cell exposed to the Phaleria macrocarpa (Boerl.) fruit ethyl acetate fraction (PMEAF) through Illumina Hi-Seq technologies and various in silico bioinformatics tools, JOURNAL OF ETHNOPHARMACOLOGY. 213, 118-131. doi:10.1016/j.jep.2017.11.009
  35. Lee, Tse-Ang; Liao, Wei-Hao; Wu, Yi-Fan; Chen, Yeng-Long; Tung, Yi-Chung (2018). Electrofluidic Circuit-Based Microfluidic Viscometer for Analysis of Newtonian and Non-Newtonian Liquids under Different Temperatures, ANALYTICAL CHEMISTRY. 90(3), 2317-2325. doi:10.1021/acs.analchem.7b04779
  36. Pachaiappan, Raman; Tamboli, Ekant; Acharya, Aurovind; Su, Chia-Hung; Gopinath, Subash C. B.; Chen, Yeng; Velusamy, Palaniyandi (2018). Separation and identification of bioactive peptides from stem of Tinospora cordifolia (Willd.) Miers, PLOS ONE. 13(3). doi:10.1371/journal.pone.0193717
  37. Gopinath, S. C. B., Perumal, V., Rao, B. S., Arshad, M. K. M., Voon, C. H., Lakshmipriya, T., Haarindraprasad, R., Vijayakumar, T., Chen, Y., Hashim, U. (2017). Voltammetric immunoassay for the human blood clotting factor IX by using nanogapped dielectrode junctions modified with gold nanoparticle-conjugated antibody. Microchimica Acta, 184(10), 3739-3745. doi: 10.1007/s00604-017-2389-7
  38. Kavitha, Nowroji; Chen, Yeng; Kanwar, Jagat R.; Sasidharan, Sreenivasan (2017). In situ morphological assessment of apoptosis induced by Phaleria macrocarpa (Boerl.) fruit ethyl acetate fraction (PMEAF) in MDA-MB-231 cells by microscopy observation, BIOMEDICINE & PHARMACOTHERAPY. 87, 609-620. doi:10.1016/j.biopha.2016.12.127
  39. Kavitha, Nowroji; Oon, Chern Ein; Chen, Yeng; Kanwar, Jagat R.; Sasidharan, Sreenivasan (2017). Phaleria macrocarpa (Boerl.) fruit induce G0/G1 and G2/M cell cycle arrest and apoptosis through mitochondria-mediated pathway in MDA-MB-231 human breast cancer cell, JOURNAL OF ETHNOPHARMACOLOGY. 201, 42-55. doi:10.1016/j.jep.2017.02.041
  40. Shanmugapriya; Chen, Yeng; Kanwar, Jagat R.; Sasidharan, Sreenivasan (2017). Anticancer Activity and Molecular Mechanism of Polyphenol Rich Calophyllum inophyllum Fruit Extract in MCF-7 Breast Cancer Cells, NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL. 69(8), 1308-1324. doi:10.1080/01635581.2017.1367944
  41. Vijayarathna, Soundararajan; Chen, Yeng; Kanwar, Jagat R.; Sasidharan, Sreenivasan (2017). Standardized Polyalthia longifolia leaf extract (PLME) inhibits cell proliferation and promotes apoptosis: The anti-cancer study with various microscopy methods, BIOMEDICINE & PHARMACOTHERAPY. 91, 366-377. doi:10.1016/j.biopha.2017.04.112
  42. Vijayarathna, Soundararajan; Oon, Chern Ein; Chen, Yeng; Kanwar, Jagat R.; Sasidharan, Sreenivasan (2017). Polyalthia longifolia Methanolic Leaf Extracts (PLME) induce apoptosis, cell cycle arrest and mitochondrial potential depolarization by possibly modulating the redox status in hela cells, BIOMEDICINE & PHARMACOTHERAPY. 89, 499-514. doi:10.1016/j.biopha.2017.02.075
  43. Gopinath, Subash C. B.; Lakshmipriya, Thangavel; Chen, Yeng; Arshad, M. K. Md; Kerishnan, Jesinda P.; Ruslinda, A. R.; Al-Douri, Y.; Voon, C. H.; Hashim, Uda (2016). Cell-targeting aptamers act as intracellular delivery vehicles, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 100(16), 6955-6969. doi:10.1007/s00253-016-7686-2
  44. Gopinath, Subash C. B.; Lakshmipriya, Thangavel; Chen, Yeng; Phang, Wai-Mei; Hashim, Uda (2016). Aptamer-based 'point-of-care testing', BIOTECHNOLOGY ADVANCES. 34(3), 198-208. doi:10.1016/j.biotechadv.2016.02.003
  45. Gopinath, Subash C. B.; Perumal, Veeradasan; Kumaresan, Ramanujam; Lakshmipriya, Thangavel; Rajintraprasad, Haarindraprasad; Rao, Balakrishnan S.; Arshad, M. K. Md; Chen, Yeng; Kotani, Norito; Hashim, Uda (2016). Nanogapped impedimetric immunosensor for the detection of 16 kDa heat shock protein against Mycobacterium tuberculosis, MICROCHIMICA ACTA. 183(10), 2697-2703. doi:10.1007/s00604-016-1911-7
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ESCI
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Scopus
  1. Adam H., Gopinath S.C.B., Krishnan H., Adam T., Fakhri M.A., Salim E.T., Shamsher A., Subramaniam S., Chen Y. (2025). Selective detection of alpha synuclein amyloid fibrils by faradaic and non-faradaic electrochemical impedance spectroscopic approaches, Bioelectrochemistry. 161. doi:10.1016/j.bioelechem.2024.108800
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  3. Hemagirri M., Chen Y., Gopinath S.C.B., Adnan M., Patel M., Sasidharan S. (2024). RNA-sequencing exploration on SIR2 and SOD genes in Polyalthia longifolia leaf methanolic extracts (PLME) mediated anti-aging effects in Saccharomyces cerevisiae BY611 yeast cells, Biogerontology. 25(4), 705-737. doi:10.1007/s10522-024-10104-y
  4. Sumaira S., Vijayarathna S., Hemagirri M., Adnan M., Hassan M.I., Patel M., Gupta R., Shanmugapriya, Chen Y., Gopinath S.C.B., Kanwar J.R., Sasidharan S. (2024). Plant bioactive compounds driven microRNAs (miRNAs): A potential source and novel strategy targeting gene and cancer therapeutics, Non-coding RNA Research. 9(4), 1140-1158. doi:10.1016/j.ncrna.2024.06.003
  5. Teow J.Y., Zhang Q., Abidin S.A.Z., Tan C.C., Abdul Rahman S.N.S., Karsani S.A., Othman I., Chen Y., Lakshmipriya T., Gopinath S.C.B. (2024). Pioneering biosensor approaches for oral squamous cell carcinoma diagnosis: A comprehensive review, Process Biochemistry. 141, 71-81. doi:10.1016/j.procbio.2024.02.015
  6. Grace-Lynn, C., Darah, I., Chen, Y., Latha, L. Y., Jothy, S. L., Sasidharan, S. (2012). In Vitro antioxidant activity potential of Lantadene A, a pentacyclic triterpenoid of Lantana plants, Molecules. 17(9), 11185-1119814203049 (ISSN).
  7. Jothy, S. L., Aziz, A., Chen, Y., Sasidharan, S. (2012). Antioxidant activity and hepatoprotective potential of polyalthia longifolia and cassia spectabilis leaves against paracetamol-induced liver injury, Evidence-based Complementary and Alternative Medicine. 2012(1741427X (ISSN). )
  8. Jothy, S. L., Torey, A., Darah, I., Choong, Y. S., Saravanan, D., Chen, Y., Latha, L. Y., Deivanai, S., Sasidharan, S. (2012). Cassia spectabilis (DC) Irwin et Barn: A promising traditional herb in health improvement, Molecules. 17(9), 10292-1030514203049 (ISSN).
  9. Jothy, S. L., Zakariah, Z., Chen, Y., Sasidharan, S. (2012). In vitro, in situ and in vivo studies on the anticandidal activity of Cassia fistula seed extract, Molecules. 17(6), 6997-700914203049 (ISSN).
  10. Mahdi-Pour, B., Jothy, S. L., Latha, L. Y., Chen, Y., Sasidharan, S. (2012). Antioxidant activity of methanol extracts of different parts of Lantana camara, Asian Pacific Journal of Tropical Biomedicine. 2(12), 960-96522211691 (ISSN).
  11. Jothy, S. L., Zakaria, Z., Chen, Y., Lau, Y. L., Latha, L. Y., Sasidharan, S. (2011). Acute oral toxicity of methanolic seed extract of Cassia fistula in mice, Molecules. 16(6), 5268-5282
  12. Jothy, S. L., Zakaria, Z., Chen, Y., Lau, Y. L., Latha, L. Y., Shin, L. N., Sasidharan, S. (2011). Bioassay-directed isolation of active compounds with antiyeast activity from a cassia fistula seed extract, Molecules. 16(9), 7583-7592
  13. Nithianantham, K., Shyamala, M., Chen, Y., Latha, L. Y., Jothy, S. L., Sasidharan, S. (2011). Hepatoprotective potential of clitoria ternatea leaf extract against paracetamol induced damage in mice, Molecules. 16(12), 10134-10145
  14. Tan, A. A., Azman, S. N., Abdul Rani, N. R., Kua, B. C., Sasidharan, S., Kiew, L. V., Othman, N., Noordin, R., Chen, Y. (2011). Optimal protein extraction methods from diverse sample types for protein profiling by using Two-Dimensional Electrophoresis (2DE), Tropical Biomedicine. 28(3), 620-629
  15. Lau, Y. L., Meganathan, P., Sonaimuthu, P., Thiruvengadam, G., Nissapatorn, V., Chen, Y. (2010). Specific, sensitive, and rapid diagnosis of active toxoplasmosis by a loop-mediated isothermal amplification method using blood samples from patients, Journal of Clinical Microbiology. 48(10), 3698-370200951137
  16. Tang, E., Dai, Y. M., Chen, Y., Lang, J. P., Yao, Y. G., Weng, N. S. (2010). Encapsulation of unique anionic carboxylic acid/water cluster chains into channels of a three-dimensional cationic framework, Inorganic Chemistry Communications. 13(7), 887-89013877003
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  20. Bao, F., Chen, Y., Ng, S. W. (2006). A cocrystal of 3-nitrophenylanilinium perchlorate and 3-nitroaniline, Acta Crystallographica Section E: Structure Reports Online. 62(9), Article
Others
  1. JingZhao, WenlongChang, LuLiu, XiaomingXing, ChaoZhang, HuihongMeng, Subash C.B.Gopinathd, Thangavel Lakshmipriya, YengChen, Yonggang Liua (2021) Graphene oxide-gold nanoparticle-aptamer complexed probe for detecting amyloidbeta oligomer by ELISA-based immunoassay. Journal of Immunological Methods (accepted)
  2. Wong Y, Ramanathan A, Yuen KM, Mustafa WMW, Abraham MT, Tay KK, Rahman ZAA, Chen Y. 2021. Comparative sera proteomics analysis of differentially expressed proteins in oral squamous cell carcinoma. PeerJ 9:e11548 https://doi.org/10.7717/peerj.11548
  3. Balasupramaniam Kirubakari, Yeng Chen, Jagat R. Kanwar, Lai Ngit Shin and Sreenivasan Sasidharan (2020) Studies on In vitro Interaction of Ampicillin and Polyalthia longifolia Leaf Ethyl Acetate Fraction (PLEAF) by Checkerboard Method Against Methicillin Resistant Staphylococcus aureus (MRSA), Vol 16, 9, 2020 DOI: 10.2174/1573407215666191102161341, Current Bioactive Compounds
  4. Balasupramaniam Kirubakari, Yeng Chen, Sreenivasan Sasidharan (2020) Synergistic Effect of Polyalthia longifolia Leaf and Antibiotics against Clinical Isolates of Methicillin-Resistant Staphylococcus aureus (MRSA) by Microscopic Technique, Vol 19, 3, DOI : 10.2174/1871523018666190522112902, Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
  5. Sreenivasan Sasidharan1, Rajandran R Kushha, Rajoo Amala, Ismail Aziah, Yeng Chen (2020). Antibacterial activity of Ecliba alba L polyphenols on survivability of Leptospira interrogans in cooked rice and tea: a green antimicrobial strategy for safe food preparation. vol 27, 5, wulfenia journal
  6. Usharani B, Ghee Seong L, Yen C (2020).Ethics, professionalism and legal education in Malaysian undergraduate dentistry: a reflection on the current requirements. Journal of Health and Translational Medicine (JUMMEC 2020)
  7. Usharani Balasingam , Lim Ghee Seong and Chen Yeng (2020) ETHICS, PROFESSIONALISM AND LEGAL EDUCATION IN MALAYSIAN UNDERGRADUATE DENTISTRY: A REFLECTION ON THE CURRENT REQUIREMENTS.
  8. Yue Huang, Li Zhang, Zhenzuo Li, Subash C. B. Gopinath, Yeng Chen, Yan Xiao, Aptamer 17 estradiol antibody sandwich ELISA for determination of gynecological endocrine function. https://doi.org/10.1002/bab.2008. Biotechnology and Applied Biochemistry.
  9. Balasupramaniam Kirubakari, Yeng Chen, Sreenivasan Sasidharan (2019) Synergistic Effect of Polyalthia longifolia Leaf and Antibiotics against Clinical Isolates of Methicillin-Resistant Staphylococcus aureus (MRSA) by Microscopic Technique
  10. Sivapragasam Gothai, Soundararajan Vijayarathna1, Yeng Chen, Ngit Shin Lai, Habibah A. Wahab, Hariri Firdaus, Subramaniam Sreeramanan, and Sreenivasan Sasidharana,(2019) IN VITRO AND IN VIVO-SCIENTIFIC EVALUATION ON CYTOTOXICITY AND GENOTOXICITY OF TRADITIONAL MEDICINAL PLANT COUROUPITA GUIANENSIS AUBL. FLOWER
  11. In vitro-scientific evaluation on anti-Candida albicans activity, antioxidant properties, and phytochemical constituents with the identification of antifungal active fraction from traditional medicinal plant Couroupita guianensis Aubl. Flower. Complementary Medicine Research 8(2):85-101 July 2018
  12. Anasdass, J. R., Kannaiyan, P., Raghavachary, R., Gopinath, S. C., & Chen, Y. (2018). Palladium nanoparticle-decorated reduced graphene oxide sheets synthesized using Ficus carica fruit extract: A catalyst for Suzuki cross-coupling reactions. PloS one, 13(2), e0193281.
  13. Kumar, U. S. U., Jothy, S. L., Kavitha, N., Chen, Y., Kanwar, J. R., & Sasidharan, S. Genoprotection and Cytotoxicity of Cassia surattensis Seed Extract on Vero Cell Evaluated by Comet and Cytotoxicity Assays. Proceedings of the National Academy of Sciences, India Section B: Biological Sciences, 1-8.
  14. Ng,ML., Shanmugapriya, Vijayarathna, S., Chen, Y., Lim, GS, Sasidharan, S.(2018).Role of Reactive oxygen species (ROS) in aging and aging-related diseases. Research Journal of Pharmaceutical, Biological and Chemical Sciences
  15. Nowroji Kavitha, Angeline Torey, Soundararajan Vijayarathna, Shanmugapriya, Yeng Chen, Jagat R. Kanwar, Subramanion L. Jothy and Sreenivasan Sasidharan. Traditional medicinal plant Phaleria macrocarpa (Scheff.) Boerl Prove its Worth in Modern Scientific Laboratory: Synergizing Ancient and Scientific Knowledge on Herbal Remedies for Future Clinical Usage. Research Journal of Pharmaceutical, Biological and Chemical Sciences
  16. Pachaiappan R, Tamboli E, Acharya A, Su C-H, Gopinath SCB, Chen Y, et al. (2018) Separation and identification of bioactive peptides from stem of Tinospora cordifolia (Willd.) Miers. PLoS ONE 13(3): e0193717. https://doi.org/10.1371/journal.pone.0193717
  17. Soundararajan V, Nowroji K, Shanmugapriya, Yeng C, Jagat R. K, and Sreenivasan S*. (2018). Apoptotic Programmed Cell Death in Cancer and The Modern Methods for Detection of Apoptotic Cells: A Mini Review.RES J PHARM BIOL CHEM SCI, 9(3),69.
  18. Cheen, O. C., Gopinath, S. C., Perumal, V., Arshad, M. M., Lakshmipriya, T., Chen, Y., ... & Pandian, K. (2017). Aptamer-based impedimetric determination of the human blood clotting factor IX in serum using an interdigitated electrode modified with a ZnO nanolayer. Microchimica Acta, 184(1), 117-125.
  19. Jothy, S. L., Saito, T., Kanwar, J. R., Kavitha, S., Chiuan, L., Herng, Y. C., ... & Sasidharan, S. (2017). Bioassay-Guided Isolation and Antioxidant Evaluation of Rutin from Leaf of Polyalthia longifolia. Asian Journal of Applied Sciences (ISSN: 2321 0893), 5(01).
  20. Kavitha, N., Chen, Y., Kanwar, J. R., & Sasidharan, S. (2017). In situ morphological assessment of apoptosis induced by Phaleria macrocarpa (Boerl.) fruit ethyl acetate fraction (PMEAF) in MDA-MB-231 cells by microscopy observation. Biomedicine & Pharmacotherapy, 87, 609-620.
  21. Shanmugapriya, Chen, Y., Kanwar, J. R., & Sasidharan, S. (2017). Anticancer Activity and Molecular Mechanism of Polyphenol Rich Calophyllum inophyllum Fruit Extract in MCF-7 Breast Cancer Cells. Nutrition and cancer, 69(8), 1308-1324
  22. Vijayarathna, S., Oon, C. E., Chen, Y., Kanwar, J. R., & Sasidharan, S. (2017). Polyalthia longifolia Methanolic Leaf Extracts (PLME) induce apoptosis, cell cycle arrest and mitochondrial potential depolarization by possibly modulating the redox status in hela cells. Biomedicine & Pharmacotherapy, 89, 499-514. doi: http://dx.doi.org/10.1016/j.biopha.2017.02.075
  23. Gopinath SCB, Perumal V, Kumaresan R, Lakshmipriya T, Rajintraprasad H, Rao BS, Md Arshad MK, Chen Y, Kotani N & Hashim U (2016). Nanogapped impedimetric immunosensor for the detection of 16 kDa heat shock protein against Mycobacterium tuberculosis. Microchimica Acta, 1-7.
  24. Gopinath, S.C., Lakshmipriya, T., Chen, Y., Phang, W.M. and Hashim, U., 2016. Aptamer-based point-of-care testing . Biotechnology advances, 34(3): 198-208.
  25. JEGATHAMBIGAI RAMESHWAR NAIDU, MANISH GUNJAN, YENG CHEN & SREENIVASAN SASIDHARAN 2016. EVALUATION OF IN VITRO CYTOTOXIC ACTIVITY OF OCIMUM BASILICUM AND MENTHA SPICATA EXTRACTS. Asian J Pharm Clin Res 9(3): 131-134.
  26. Kumar U.S.U., Jothy S.L., Kavitha N., Chen Y., Kanwar J.R., Sasidharan S. 2016. Genoprotection and Cytotoxicity of Cassia surattensis Seed Extract on Vero Cell Evaluated by Comet and Cytotoxicity Assays. Proceedings of the National Academy of Sciences, India Section B: Biological Sciences. 2016:1-8.
  27. Logaranjan, K., Raiza, A. J., Gopinath, S. C., Chen, Y., & Pandian, K. (2016). Shape-and Size-Controlled Synthesis of Silver Nanoparticles Using Aloe vera Plant Extract and Their Antimicrobial Activity. Nanoscale Research Letters, 11(1), 520.
  28. Phang W.M., Tan A.A., Gopinath S.C.B., Hashim O.H., Kiew L.V. & Chen Y. 2016. Secretion of N- and O-linked Glycoproteins from 4T1 Murine Mammary Carcinoma Cells. Int J Med Sci, 13(5): 330-339.
  29. Shanmugapriyaa, Chen, Y., Kanwar, J. R., & Sasidharan, S. (2016). Effects of Calophyllum inophyllum fruit extract on the proliferation and morphological characteristics of human breast cancer cells MCF-7. Asian Pacific Journal of Tropical Disease, 6(4): 291-297.
  30. Uthaya Kumar, U. S., Chen, Y., Kanwar, J. R., & Sasidharan, S. (2016). Redox Control of Antioxidant and Antihepatotoxic Activities of Cassia surattensis Seed Extract against Paracetamol Intoxication in Mice: In Vitro and In Vivo Studies of Herbal Green Antioxidant. Oxidative Medicine and Cellular Longevity, 2016.
  31. Aik-Aun Tan, Wai-Mei Phang, Subash C B Gopinath, Onn H Hashim, Lik Voon Kiew and Yeng Chen (2015). Revealing Glycoproteins in the Secretome of MCF-7 Human Breast Cancer Cells. Biomed Research International
  32. Angeline Torey, Soundararajan Vijayarathna, Subramanion L. Jothy, Sivapragasam Gothai, Yeng Chen, Lachimanan Yoga Latha, Jagat R. Kanwar, Saravanan Dharmaraj, Sreenivasan Sasidharan (2015). Exploration of the anticandidal mechanism of Cassia spectabilis in debilitating candidiasis. Journal of Traditional and Complementary Medicine
  33. Jegathambigai R Naidu, Rusli Ismail, Ponnusamy Kumar, Subramanion L Jothy, Yeng Chen and Sreenivasan Sasidharan 2015. Antiplatelet Activity and Quantification of Polyphenols Content of Methanol Extracts of Ocimum basilicum and Mentha spicata. Research Journal of Pharmaceutical, Biological and Chemical Sciences 6(5): 1236-1244.
  34. Jonathan Liew, Amirah Amir, Yeng Chen, Mun Yik Fong, Rozaimi Razali, Yee Ling Lau (2015). Autoantibody profile of patients infected with knowlesi malaria, Clinica Chimica Acta; International Journal of Clinical Chemistry 2015; 448
  35. Jothy, S.L., Vijayarathna, S., Chen, Y., Kanwar, J.R. & Sasidharan, S. 2015. Regulating Mitochondrial Biogenesis: from Herbal Remedies to Phytomedicine for Cancer Prevention. Asian Pacific Journal of Cancr Prevention 16(17): 8015.
  36. Marimuthu C, Subash CBG, Chen Y, Thangavel L and Tang TH. Monitoring recombinant human erythroietin abuse amoung athletes. Biosensors and Bioelectronics
  37. Sasidharan S, Jothy SL, Kavitha N, Chen Y, Kanwar JR 2015. Deactivation of Telomerase Enzyme and Telomere Destabilization by Natural Products: a Potential Target for Cancer Green Therapy. Asian Pac J Cancer Prev. 16(18):8671.
  38. Soundararajan Vijayarathna, Subramanion L Jothy, Yeng Chen, Jagat R Kanwar, Sreenivasan Sasidharan (2015). Anti-Cancer Natural Products Inducing Cross-talk between Apoptosis and Autophagy Mutual Proteins to Regulate Cancer Cell Death: Design of Future Green Anticancer Therapies. Asian Pacific Journal Of Cancer Prevention 16(14):6175-6
  39. Subash C. B. Gopinath, Periasamy Anbu, Thangavel Lakshmipriya, Thean-Hock Tang, Yeng Chen, Uda Hashim, A. Rahim Ruslinda, and M.K.Md Arshad (2015). Biotechnological Aspects and Perspective of Microbial Keratinase Production. Biomed Research International, 2015
  40. Subash C.B. Gopinath, Ramanujam Kumaresan, Toshiyasu Nishimura, Thangavel Lakshmipriya, Thean-Hock Tang, Yeng Chen & Uda Hashim 2015. Investigation on Optimally Performing Sensor Substrates through Bio-fouling of Immunoglobulin-Conjugated Gold Nanoparticles. Proceedings of the National Academy of Sciences, India Section B: Biological Sciences : 1-8.
  41. Subramanion L. Jothy, Tamio Saito, Jagat R. Kanwar, Yeng Chen, Azlan Aziz, Leong Yin-Hui, Sreenivasan Sasidharan 2015. Radioprotective activity of Polyalthia longifolia standardized extract against X-ray radiation injury in mice. Physica Medica.
  42. Subramanion L. Jothy, Yeng Chen, Soundararajan Vijayarathna, Jagat R. Kanwar, Sreenivasan Sasidharan (2015). MicroRNAs: Association with Radioresistant and Potential Uses of Natural Remedies as Green Gene Therapeutic Approaches. Current Gene Therapy 15(1)
  43. Vijayarathna, S., Gothai, S., Jothy, S.L., Chen, Y., Kanwar, J.R., Sasidharan, S. 2015. Can Cancer Therapy be Achieved by Bridging Apoptosis and Autophagy: a Method Based on microRNA-Dependent Gene Therapy and Phytochemical Targets. Asian Pacific Journal of Cancer Prevention 16(17): 7435-9.
  44. Yeng Chen, Choon K Chan, Jesinda P Kerishnan, Yee L Lau, Yin-Ling Wong, Subash CB Gopinath (2015). Identification of circulating biomarkers in sera of Plasmodium knowlesi-infected malaria patients comparison against Plasmodium vivax infection, BMC Infectious Diseases 15(1):49
  45. Yeng Chen, Wai-Mei Phang, Alan Kang-Wai Mu, Choon-Keat Chan, Bin-Seng Low, Sreenivasan Sasidharan, Kit-Lam Chan 2015. Decreased expression of alpha-2-HS glycoprotein in the sera of rats treated with Eurycoma longifolia extract. Frontiers in Pharmacology, 6:211.
  46. Yuet Ping Kwan, Tamio Saito, Darah Ibrahim, Faisal Muti Saleh Al-Hassan, Chern Ein Oon, Yeng Chen, Subramanion L Jothy, Jagat R Kanwar, Sreenivasan Sasidharan (2015). Evaluation of the cytotoxicity, cell-cycle arrest, and apoptotic induction by Euphorbia hirta in MCF-7 breast cancer cells. Pharmaceutical Biology 8: 1-14
  47. Aik Aun Tan, Alan Kang Wai Mu and Yeng Chen (2014) Comparative secretomic and N-glycoproteomic profiling in human MCF-7 breast cancer and HMEpC normal epithelial cell lines using a gel-based strategy. Cancer Cell International.
  48. Lau, Y.L., Cheong, F.W., Chin, L.C., Mahmud, R., Chen, Y. and Fong, M.Y (2014). Evaluation of codon optimized recombinant Plasmodium knowlesi Merozoite Surface Protein-119 (pkMSP-119) expressed in Pichia pastoris. Tropical Biomedicine
  49. Mu, A.K., Chan, Y.S., Kang, S.S., Azman, S.N., Zain, R., Chai, W.L., Chen, Y. (2014). Detection of host-specific immunogenic proteins in the saliva of patients with oral squamous cell carcinoma. J Immunoassay Immunochem. 35(2):183-193.
  50. Nowroji Kavitha, Soundararajan Vijayarathna, Subramanion Lachumy Jothy, Chern Ein Oon, Yeng Chen, Jagat Rupinder Kanwar, Sreenivasan Sasidharan. MicroRNAs: Biogenesis, roles for carcinogenesis and as potential biomarkers for cancer diagnosis and prognosis. Asian Pacific Journal of Cancer Prevention, Vol 15
  51. Subash CBG, Tang TH, Chen Y, Marimuthu C, Thangavel L. Bacterial Detection: from Microscope to Smartphone. Biosensors and Bioelectronics. 2014; 60:332-342
  52. Sumathy V, Zakariah Z, Jothy SL, Gothai S, Vijayarathna S, Latha LY, Chen Y, Sasidharan S. In vitro and in vivo antifungal activity of Cassia surattensis flower against Aspergillus niger. Microbial Pathogenesis, DOI: 10.1016/j.micpath.2014.10.004
  53. U. Seeta Uthaya Kumar, Subramanion L. Jothy, Sivapragasam Gothai, Saravanan Dharmaraj, Yeng Chen, Sreenivasan Sasidharan. Standardization and Quality Evaluation of Cassia surattensis seed extract. Research Journal of Pharmaceutical, Biological and Chemical Sciences 5(5):355-363
  54. Kuppan Nithianantham, Kwan Yuet Ping, Lachimanan Yoga Latha, Subramanion L Jothy, Ibrahim Darah, Yeng Chen, Ai-Lan Chew, Sreenivasan Sasidharan. 2013. Evaluation of hepatoprotective effect of methanolic extract of Clitoria ternatea (Linn.) flower against acetaminophen-induced liver damage. Asia Pacific Journal of Tropical Disease Aug 3(4): 314-319
  55. Kwan Yuet Ping, Ibrahim Darah, Yeng Chen, Sreenivasan Sasidharan. 2013. Cytotoxicity and genotoxicity assessment of Euphorbia hirta in MCF-7 cell line model using comet assay. Asia Pacific Journal of Tropical Biomedicene Sep 3(9): 692-5
  56. Subramanion L. Jothy, Chern Ein Oon, Subramaniam Devanai, Dharmaraj Saravanan, Soundararajan Vijayarathna, Yee Siew Choong, Chenyeng, Lachimanan Yoga Latha, Sreenivasan Sasidharan (2013). Herbal remedies for combating irradiation: A green Anti Irradiation Apaproach. Asian Pacific Journal Cancer Prevention.
  57. Subramanion L Jothy, Yeng Chen, Jagat R. Kanwar, Sreenivasan Sasidharan (2013). Evaluation of the Genotoxic Potential against H202-Radical-Mediated DNA Damage and Acute Oral Toxicity of Standardized Extract of Polyathia longifolia Leaf. Evidence- Based Complementary and Alternative Medicine.
  58. Yunn Shy Chan, Szu Szu Kang, Alan Kang-Wai Mu, Siti Nuraishah Azman, Rosnah Mohd Zain, Wen Lin Chai , Yeng Chen. (2013). Detection of Host-Specific Immunogenic Proteins in the Saliva of Patients with Oral Squamous Cell Carcinoma. Journal of Immunoassay and Immunochemistry
  59. Badakhshan Mahdi-Pour, Subramanion L. Jothy, Lachimanan Yoga Latha, Yeng Chen & Sreenivasan Sasidharan. 2012. Antioxidant activity of methanol extracts of different parts of Lantana camara. Asia Pacific Journal of Tropical Biomedicine.
  60. Grace-Lynn C., Chen Y., Latha l.Y., Kanwar J.R., Jothy S.L., Vijayarathna S. & Sasidharan S. 2012. Evaluation of the hepatoeffects of Lantadene A, pentacyclic tripenoid of Lantana plants against Acetaminophen-induced liver damage. Molecules. 17(12): 13937-13947.
  61. Grace-Lynn C., Darah I., Chen Y., latha L.Y., Jothy S.L. & Sasidharan S. 2012. In vitro antioxidant activity potential of Iantadene A, a pentacyclic triterpenoid of Lantana plants. Molecules. 17(9): 11185-11198.
  62. J. Rameshwar Naidu, R.B.Ismail, Chen Y., Sasidharan S. & Kumar P. 2012. Chemical composition and antioxidant activity of the crude mathanolic extracts of Mentha spicata. Journal of Phytology. 4(1): 13-18.
  63. Jothy S.L., Chen Y.,Sasidharan S., & azlan Aziz. 2012. Antioxidant activity and hepatoproctective potential of Polyalthia longifolia and Cassia spectabilis leaves against paracetamol-induced liver injury. Evidence-Based Complementary and Alternative Medicine.
  64. Jothy S.L., Torey A., Darah I., Choong Y.S.,Saravanan D., Chen Y., Latha L.Y., Deivanai S. & Sasidharan S. 2012. Cassia spectabilis (DC) Irwin et barn: a promising traditional herb in health improvement. Molecules. 17(9): 10292-10305.
  65. Jothy S.L., Zakaria Z., Chen Y. & Sasidharan S. 2012. In vitro, in situ and in vivo studies on the anticandidal activity of Cassia fistula seed extract. Molecules. 17(6): 6997-7009.
  66. Vijayarathna S., Zakaria Z., Chen Y., Latha L.Y., Kanwar J.R, Sasidharan S. 2012. The antimicrobial efficacy of Elaeis guineensis: Chanracterization, in vitro and in vivo studies. Molecules. 17(5): 4860-77.
  67. Aik Aun Tan, Siti Nuraishah Azman, Nurulhasanah Othman, Nik Rahimah Abdul Rani, Beng Chu Kua, Sreenivasan Sasidharan, Lik Voon Kiew, Rahmah Noordin and Yeng Chen (2011). Optimal protein extraction methods from diverse sample types for protein profiling by using Two-Dimensional Electrophoresis (2DE), Tropical Biomedicine
  68. Hepatoprotective Potential of Clitoria ternatea Leaf Extract Against Paracetamol Induced Damage in Mice Kuppan Nithianantham, Murugesan Shyamala, Yeng Chen, Lachimanan Yoga Latha, Subramanion L. Jothy and Sreenivasan Sasidharan. molecules 6;16(12):10134-45
  69. S. Sasidharan, Y. Chen, D. Saravanan, KM Sundram and L. Yoga Latha (2011). Extraction, isolation and characterization of bioactive compounds from plants extracts. Afr J Tradit Complement Altern Med. 8(1) (review paper for 2011 edition)
  70. Subramanion L. Jothy, Zuraini Zakaria, Yeng Chen, Yee Ling Lau, Lachimanan Yoga Latha, Lai Ngit Shin and Sreenivasan Sasidharan (2011). Bioassay-Directed Isolation of Active Compounds with Antiyeast Activity from a Cassia fistula Seed Extract. Molecules. 2011 Sep 5;16(9):7583-92.
  71. Subramanion L. Jothy, Zuraini Zakaria, Yeng Chen, Yee Ling Lau, Sreenivasan Sasidharan (2011). Acute Oral Toxicity of methanolic seeds extract of Cassia fistula in mice. Molecules 2011 Jun 23;16(6):5268-82
  72. Yee-Ling Lau, Mun-Yik Fong, Rohela Mahmud, Phooi-Yee Chang, Vanitha Palaeya, Fei-Wen Cheong, Lit-Chein Chin, Claudia N Anthony, Abdulsalam MQ Al-Mekhlafi and Yeng Chen (2011). Specific, sensitive and rapid detection of human Plasmodium knowlesi infection by loop-mediated isothermal amplification (LAMP) in blood samples. Malar J. 2011 Jul 20;10:197
  73. Abdul Rani Muhamad Syahmi, Soundararajan Vijayaratna, Sreenivasan Sasidharan, Lachimanan Yoga Latha, Yuet Ping Kwan, Yee Ling Lau, Lai Ngit Sin, Yeng Chen (2010). Acute Oral Toxicity of Elaeis guineensis Jacq. (Oil Palm Leaf) Methanol Extract. Molecules 10; 15 (11):8111-21.
  74. Angeline Torey, Sreenivasan Sasidharan, Chen Yeng and Lachimanan Yoga Latha. (2010). Standardization of Cassia spectabilis with respect to authenticity, assay and chemical constituent analysis. Molecules, 15(5), 3411-3420.
  75. Chen Yeng, Osman Emelia, Mohamed Zeehaida, and Noordin Rahmah (2010). Differential expression of immunogenic parasite and host-specific proteins in the sera of active and chronic individuals infected with Toxoplasma gondi. Electrophoresis Nov 16
  76. O. Emelia, M. Zeehaida, O. Sulaiman, M. Rohela, G. Saadatnia, C. Yeng and N. Rahmah (2010). Detection of Circulating T. gondii Antigen in the Sera of Toxoplasmosis Patients. Journal of Immunoassay & Immunochemistry, 31:79 91.
  77. Othman N, Mohamed Z, Verweij JJ, Huat LB, Olivos- Garc A, Yeng C, Noordin R. (2010) Application of Real-Time Polymerase Chain Reaction in Detection of Entamoeba histolytica in Pus Aspirates of Liver Abscess Patients. Foodborne Pathog Dis. 7(6):637-41.
  78. Yee Ling Lau, Puviarasi Meganathan, Parthasarathy Sonaimuthu, Girija Thiruvengadam, Veeranoot Nissapatorn and Yeng Chen. (2010) Specific, sensitive and rapid detection of Toxoplasma gondii in blood by loop-mediated isothermal amplification (LAMP) method. J Clin Microbiol. 2010 Oct; 48(10):3698-702.
  79. Yeng Chen, Boon-Kiong Lim and Onn Haji Hashim (2009). Different altered stage correlative expression of high abundance acute-phase proteins in sera of patients with epithelial ovarian carcinoma. Journal of Hematology & Oncology, 2:37.
  80. Emida Mohamed, Puteri Shafinas Abdul Rahamn, Saeid Reza Doustjalali, Yeng Chen et al. (2008). Lectin based electrophoretic analytic of the expression of 35 Kda inter-alpha trypsin inhibitor hearvy chain H4 fragment in the sera of patients with different malignancy. Electrophoresis, 29, (12): 2645- 2650.
  81. Yeng Chen, Boon-Kiong Lim, Suat-Cheng Peh and Onn Haji Hashim (2008). Profiling of serum and tissue high abandance acute-phase proteins of patients with epithelial and germ line ovarian carcinoma. Proteome Science, 6:20.
Chapter in Books
  1. ussaini Adam, Yeng Chen, Subash C. B. Gopinath & Tijjani Adam (2023) Surface Engineered Nanobiosensor for Disease Biomarker Identification, Surface Engineering and Functional Nanomaterials for Point-of-Care Analytical Devices pp 173–197
  2. Braganza Cilwyn, Soundararajan Vijayarathna, Shanmugapriya, Rameshwar Naidu Jegathambigai, Subramaniam Sreeramanan, Yeng Chen, and Sreenivasan Sasidharan. The Role of Phytochemicals in Cancer Prevention and Cure, Bioactive Natural Products for Pharmaceutical Applications, Springer Nature Switzerland AG 2021 D. Pal and A. K. Nayak (eds.), Bioactive Natural Products for Pharmaceutical Applications, Advanced Structured Materials 140,
  3. Kasevem Santhiya-Nair, Shanmugapriya, Perumal Logeiswariy, Subramaniam Sreeramanan, Ramachandran Shakila, Yeng Chen, Yin-Hui Leong, Sundram Karupiah, Sreenivasan Sasidharan (2021) Purification of herbal biomolecules (Pg 47-62) HERBAL BIOMOLECULES IN HEALTHCARE APPLICATIONS, Academic Press is an imprint of Elsevier
  4. Braganza Cilwyn, Soundararajan Vijayarathna, Shanmugapriya, Rameshwar Naidu Jegathambigai, Subramaniam Sreeramanan, Yeng Chen, and Sreenivasan Sasidharan. The Role of Phytochemicals in Cancer Prevention and Cure, Bioactive Natural Products for Pharmaceutical Applications, Springer Nature Switzerland AG 2021 D. Pal and A. K. Nayak (eds.), Bioactive Natural Products for Pharmaceutical Applications, Advanced Structured Materials 140,
  5. Kasevem Santhiya-Nair, Shanmugapriya, Perumal Logeiswariy, Subramaniam Sreeramanan, Ramachandran Shakila, Yeng Chen, Yin-Hui Leong, Sundram Karupiah, Sreenivasan Sasidharan (2021) Purification of herbal biomolecules (Pg 47-62) HERBAL BIOMOLECULES IN HEALTHCARE APPLICATIONS, Academic Press is an imprint of Elsevier
  6. Balasupramaniam Kirubakari, Shanmugapriya, Thiagarajan Sangeetha, Soundararajan Vijayarathna, Yeng Chen, Jagat R. Kanwar, Chiuan Herng Leow, Lai Ngit Shin, Mallappa Kumara Swamy, Sreeramanan Subramaniam, and Sreenivasan Sasidharan (2019). Antibacterial and Antifungal Agents of Higher Plants. page 493-508 Springer Nature Singapore Pte Ltd. 2019
  7. Shanmugapriya, Hisham Alkatib Huda, Soundararajan Vijayarathna, Chern Ein Oon, Yeng Chen, Jagat R. Kanwar, Mei Li Ng, and Sreenivasan Sasidharan (2018). Advances in Experimental Medicine and Biology. In J. Xiao (ed.),Functional Analysis of Circular RNAs (pp 95-105), ,Springer Nature Singapore Pte Ltd.
  8. Sasidharan, S., Jothy, S.L., Chen, Y., Vijayarathna, S., Oon, C.E. and Kanwar, J.R. 2015.Safe food Preparation with Natural Antimicrobial Polyphenol: a Preventing Strategy for Microbial Pathogens Infection during and after a Flood.A. M ez-Vilas (Ed.). The Battle Against Microbial Pathogens: Basic Science, Technological Advances and Educational Programs, 5th edition, pp. 745-756. Formatex.
  9. Gopinath, S.C.B., Citartan, M., Lakshmipriya, T., Tang, T.H. and Chen, Y. Gold Nanoparticle in Biosensing Analyses. In.: Nanoparticles' Promises and Risks - Characterization, Manipulation, and Potential Hazards to Humanity and the Environment. Ed. Mihai Lungu, Nano DEP (2014), Springer publisher.
  10. S.L. Jothy, S. Gothai, Y. Chen and S. Sasidharan. In vivo radioprotective activity analysis by light microscopy; Methodology approaches. Microscopy: advances in scientific research and education, Formatex Research Center, Spain, Microscopy Book Series - 2014 Edition
Other Publications
  1. Untuk memberi panduan kepada pelajar baru yang akan memasuki Kursus MDSc university Malaya - Technical Report

RESEARCH INTEREST

  • Identification of biomarkers for infectious and non-infectious diseases detection using proteomics and genomics techniques. (Biomarkers)
  • Development of immunogenic protein detection methods (immunogenic proteins)
  • Design and development of highly sensitive and specific biosensors for early cancer detection. (Biosensors)
  • Creation of rapid diagnostic tools and personalized treatment solutions for various diseases. (personalized treatment)
  • Investigation of plant extracts and natural compounds for their biochemical and pharmacological properties. (biochemical and pharmacological properties)
  • Application of natural products in cancer treatment, focusing on targeted therapeutic approaches. (natural product)
  • Integration of nanotechnology in cancer diagnostics and therapeutic tool development. (nanotechnology)

RESEARCH PROJECT

National
  1. 2016 - 2018, Postgraduate Research Grant (PPP) - Research
    Identification of Glycosylated Proteins Expression Pattern in Oral Squamous Cell Carcinoma ( Principal Investigator(PI))
  2. 2014 - 2016, High Impact Research - Ministry of Education (HIR-MOE) Cycle 1
    Rna Aptamer Generation By Deep Sequencing Method For Exosome Hybridization: An Aptamer Cargo For Cancer Diagnosis And Therapy ( Principal Investigator(PI))
  3. 2013 - 2015, Geran Penyelidikan Universiti Malaya (UMRG Programme) - HTM (Wellness)
    Oral Cancer Research: Diagnostic And Biobanking Services ( Co-Researcher)
  4. 2012 - 2014, Geran Penyelidikan Universiti Malaya (UMRG) - HTM (Wellness)
    Determining urinary protein biomarker from leukemia patients, a non-invasive approach ( Principal Investigator(PI))
  5. 2019 - 2021, Fundamental Research Grant Scheme (FRGS)
    Mechanism of secondary metabolites Action in Phytosynthesized iron Nanoparticle against Mosquito vector larvae causes tropical diseases and human pathogen ( Consultant)
  6. 2020 - 2021
    Microwave Synthesis of Silica Nanoparticles from Carbonaceous Chinese Joss Paper for Methylene Blue Adsorption [Grant number: 9001-00596], Universiti Malaysia Perlis (UNIMAP) ( Co-Researcher)
  7. 2012 - 2015, High Impact Research (HIR)
    Discovery of SNPs for oral cancer prognostical using GWAS and the development of protein biomarker diagnostic test for early detection of oral cancer ( Principal Investigator(PI))
  8. 2014 - 2015, High Impact Research (HIR)
    RNA aptamer generation by deep sequencing method for Exosome hybridization: an aptamer cargo for cancer diagnosis and therapy ( Principal Investigator(PI))
  9. 2010 - 2013, Geran Universiti Penyelidikan (RUI)
    Chemopreventive Activities of Phytochemicals (SIRIM Products) on Selected Cancer Cells Using Proteomics Approaches ( Co-Researcher)
  10. 2011 - 2013, Fundamental Research Grant Scheme (FRGS)
    Cellular and Molecular Mechanisms of Action of a Purified Fraction from a Novel Actinomycete Strain, Streptomyces sp. H7372 Targeted Ras / Raf Pathway in Mammalian Cell Line ( Co-Researcher)
  11. 2009 - 2012, Geran Universiti Penyelidikan (RUI)
    Expression Studies of Clusterin Isoforms in Human Breast Cancer ( Principal Investigator(PI))
  12. 2009 - 2012, Geran Univerisiti Penyelidikan (RUI)
    Identification of Protein Markers for Oral Cancer using Saliva and Investigation of its Potential to Determine Disease Progression ( Principal Investigator(PI))
  13. 2010 - 2012, Geran Universiti Penyelidikan (RUI)
    A Study on The Proteome of Plamodium Vivax and Plasmodium Falciparum in The Serum of Malaria Patients ( Co-Researcher)
  14. 2009 - 2011, Geran Universiti Penyelidikan (RUI)
    Studies On Epstein-Barr Virus Proteins as Factors Leading to Down Regulation of DNA Damage Repair Proteins in Nasopharyngeal Carcinomas ( Co-Researcher)
  15. 2008 - 2011, Fundamental Research Grant Scheme (FRGS)
    Proteomic Analysis of Entamoeba Histolytica antigens in Pus and Serum Samples of Patients with Amoebic Liver Abscess (ALA) ( Co-Researcher)
  16. 2008 - 2009, Incentive
    Standardization of Serum Protein Profile using Two Dimensional Electrophoresis Method ( Principal Investigator(PI))
International
  1. 2020 - 2022, International Funding
    Exosome Hybridizing Aptamer: A tool for Targeted cancer Diagnosis and therapy ( Consultant)
  2. 2017 - 2019, The institutional links grant
    Amino Acid Composition Analysis of Lipases from oil Pollutant Isolates : Cunninghamella verticillata and Geotrichum candidum ( Consultant)
  3. 2012 - 2017, NUS Collaboration
    A Randomized Control Trial to Assess the clinical Benefits of a Pharmacogenetics- Guided Regimen for Calculating Warfarin Maintenance Dose ( Consultant)

CONSULTANCY PROJECT

  • Ketua Auditor, University of Malaya
    01 Dec 2020 - 01 Dec 2022 (National)
  • Assessor for Elective Project (2019), university of malaya
    01 Dec 2019 - 01 Dec 2020 (National)
  • Audit Kendiri, UM
    01 Dec 2019 - 01 Dec 2020 (National)
  • Pakar Rujuk Kluster Global Issues and Community Sustainability Making The World a Better Placebagi Kursus Student Holistic Empowerment (She), University of Malaya
    01 Dec 2019 - 01 Dec 2020 (National)
  • Elective Report Assessment, dentistry
    01 Dec 2017 - 01 Dec 2018 (National)
  • Review for Bmc Complementary and Alternative Medicine, BMC Complementary and Alternative Medicine
    01 Dec 2018 - 01 Dec 2018 (International)
  • Internal Auditor, University Malaya
    01 Feb 2013 - 01 Feb 2013 (National)

PAPER PRESENTED

INVITED SPEAKER
  1. Proteomic analysis to design probe for clinical biomarkers, Workshop, Dr Subash C.B. Gopinath (National) (10 Dec 2022 - 10 Dec 2022)
  2. Glycoproteomics Analysis of Oral Squamous Cell Carcinoma , RSU International Research Conference 2019, Rangsit University, Thailand (International) (26 Apr 2019 - 26 Apr 2019)
EVENT ORGANISER
  1. Sub Theme: Emerging Technologies in Precision Medicine under the Main Theme: Advancing Precision Medicine with Emerging Technologies: Bridging Gap Between Academia and Industry. , ICDDTM 21 ONEDAY SATELLITE SYMPOSIUM under INTERNATIONAL CONFERENCE ON DRUG DISCOVERY ANDTRANSLATIONALMEDICINE2021(ICDDTM'21) , Malaysian Association for Cancer Research (MACR) (International) (01 Jan 2020 - 31 Dec 2021)
ORAL PRESENTER
  1. From Oral Cancer Biomarkers Discovery to Machine-Learning Assisted Biosensing in Early Cancer Detection, International conference in Dentistry 2021, Dental UM (International) (22 Dec 2021 - 23 Dec 2021)
PRESENTER
  1. Detection of Host-specific Immunogenic Proteins in OSCC Patients' Sera , 28th Annual Scientific Meeting of the International Association for Dental Research Southeast Asian Division , IADR-SEAADE 2014 (International) (11 Aug 2014 - 14 Aug 2014)
  2. Detection of Parasite and Host-Specific Proteins in the Sera of Individuals Infected with Plamodium knowlesi, 8th European Congress on Tropical Medicine and International Health  (International) (08 Sep 2013 - 14 Sep 2013)

ACADEMIC/ PROF. SERVICES

Evaluation
  1. (2024) Panal for Candidature Defense Report (Mohd Aizat Bin Abdul Rahim), University, (Internal Assessor)
  2. (2024) Panel Penilai for Loh Wei Tao, University, (External Assessor)
  3. (2024) Judge for The 6th Icomoi 2024, International, (External Evaluator)
  4. (2024) Panel Evaluator for Dr. Dinda Kurnia Fitri 23067625, University, (Internal Assessor)
  5. (2024) Assessor for Elective Project, University, (Internal Examiner)
  6. (2023) Evaluate Thesis Written by Dr Wendy, University, (Internal Examiner)
  7. (2023) Evaluate Thesis: Identification of Urinary Protein Biomarker for Kratom Addiction and Development of a Screening Method Using The Biomarker, National, (External Examiner)
  8. (2022) Judge to The 32nd Intervarsity Biochemistry Seminar Entitled "Skeptiko" Reveal The Unseen Perspective of Biochemistry, National, (External Examiner)
  9. (2022) Hpv and Ebv Co-Infection in Oral and Oropharyngeal Cancers: a Systematic Review and Meta-Analysis" for Oral Diseases, International, (Reviewer)
  10. (2022) Review for for Expert Review of Hematology; "Serum Exosomes from Head and Neck Squamous Cell Carcinoma Carrying Microrna-182-5p Induce Tumor Angiogenesis and Epithelial-Mesenchymal Transition by Inhibiting Ntn4 Expression", International, (Reviewer)
  11. (2022) Ms. Ref. No.: Canlet-D-22-02226 Title: The Role of Micro Tumor Thrombus During Tumor Hematogenous Metastasis: Rationale of The Tumor-Platelet Interplay Cancer Letters, International, (Reviewer)
  12. (2022) External Examiner for Phd Student Rana Khudhair Jasim Al Suwaychit from Pusat Pengajian Sains Farmasi, USM, National, (External Examiner)
  13. (2022) Title: Label Free Proteomics of Oral Mucosa Tissue to Identify Potential Biomarkers That Can Flag Predilection Ofprecancerous Lesions to Oral Cell Carcinoma: a Preliminary Study Submission Id: 381100, International, (Reviewer)
  14. (2022) Thesis Title: Identification of Serum Anti-Carbamylated Protein Antibodies in Rheumatoid Arthritis Patients With Periodontal Disease : a Pilot Study, University, (Internal Examiner)
  15. (2022) Pone-D-22-20883 Caveolin-1 Expression in Gynecological Cancers Correlates With Albumin Concentrations in The Tumor Interstitium and Serum Mrs Sadaf Azad Raja, International, (Reviewer)
  16. (2022) Panel for Proposal Entitled "in-Vitro Inactivation of Sars-Cov-2 in Dental Aerosol Generating Procedure" by Dr Wendy, University, (Internal Evaluator)
  17. (2022) Reviewer of Article; Title: Non-Oxidized and Oxidized Flaxseed Orbitides Differently Induce Hepg2 Cell Apoptosis: Involvement of Cellular Uptake and Membrane Death Receptor Dr4, International, (Reviewer)
  18. (2022) Biomedical Science Final Year Project (Mic4001 and Mic4005) Assessment, University, (Internal Examiner)
  19. (2022) Review Manuscript: Odi-05-22-Ra-11071, Entitled "Association Between Genetic Factors and Progression of Pre-Malignant Lesions to Oral Squamous Cell Carcinoma (Oscc): a Systematic", International, (Reviewer)
  20. (2022) Internal Evaluation: 2022 Dr Ranjeet Bhagwan Singh (Rbs) Medical Research Grant, University, (Internal Assessor)
  21. (2022) Evaluated Frgs Proposal, University, (Internal Evaluator)
  22. (2022) : Inhibitory Effect of Selected Indian Honey in Colon Cancer Cell Growth by Inducing Apoptosis and Targeting Catenin/Wnt Pathway, International, (Reviewer)
  23. (2022) Review Title: Streptomyces Diastaticus Mam5 L-Arginase: Purification, Characterizations, and Induction of G1 Phase Arrest and Autophagy in Human Breast Cancer McF-7 Cells, International, (Reviewer)
  24. (2022) Reviewer, International, (Reviewer)
  25. (2022) Bds Final Year Project, University, (Internal Assessor)
  26. (2022) Proteomics Analysis Reveals The Inhibitory Effects of Diethyldithiocarbamate-Copper Complex Involving Rrm2 Regulation in Lung Cancer Cells., International, (Reviewer)
  27. (2022) Editorial Board Member, International, (External Assessor)
  28. (2022) Editorial Board, International, (External Assessor)
  29. (2021) Odi-06-21-Oa-9912, Entitled "Genetic Characterization of HPV16 E6 and Lcr Variations of Oral Lesions from Argentinian Patients" for Oral Diseases., International, (Reviewer)
  30. (2021) Pone-D-20-29979 Survival and Clinicopathological Characteristics of Ct4b Oral Squamous Cell Carcinoma Based On Different Treatment Modalities: a Single-Center Retrospective Study, International, (Reviewer)
  31. (2021) External Examiner for Master in Science Entitled Expression Analysis of Gastric Cancer Associated Genes in Bpifb2 Cell Lines (Nur Amira Binti Zulkifli; Id 2015625086), UiTM, National, (External Examiner)
  32. (2021) Hermed-D-20-00460 Title: Anti-Histaminic and Anti-Arthritic Activities of Polyalthia Longifolia Essential Oils, International, (Reviewer)
  33. (2021) Angiotensin Ii Receptor Blockers Improve Survival in Patients With Locally Advanced Oral Squamous Cell Carcinoma- a Propensity-Score-Matched Study, International, (Reviewer)
  34. (2021) Phymed-D-20-02292r1 Title: Oxocrebanine: a Novel Dual Topoisomerase Inhibitor, Suppressed The Proliferation of Breast Cancer Cells McF-7 by Inducing Dna Damage and Mitotic Arrest, International, (Reviewer)
  35. (2021) Appointment as An Assessor for The Elective Project, University, (Internal Assessor)
  36. (2021) Phymed-D-20-02390 Title: Fat Regulatory Mechanisms of Pine Nut Oil Based On Protein Interaction Network Analysis Phytomedicine, International, (Reviewer)
  37. (2020) Integrated Biosensor System With Mobile Health and Wastewater-Based Epidemiology (Ibmw) for The Prevention, Surveillance, Monitoring and Intervention of Infectious Disease Epidemics Biosensors and Bioelectronics, International, (Reviewer)
  38. (2020) Reviewer for JUMMEC by Asia Pacific Journal of Molecular Biology and Biotechnology (APJMBB) , (Reviewer)
  39. (2020) Reviewer for Tropical Biomedicine (the official journal of the Malaysian Society of Parasitology and Tropical Medicine with impact factor: 0.509), (Reviewer)
  40. (2020) Consistently review and edit for the PHYOMEDICINE (impact factor: 4.11), (Advisory Committee)
  41. (2020) Reviewer for Biosensors and Bioelectronics (ISI Indexed Journal; impact factor 10.257), (Reviewer)
  42. (2020) Rapid Reviews: COVID-19 (RR:C19), (a rapid-review overlay journal that is a collaboration between UC Berkeley and the MIT Press), (Reviewer)
  43. (2019) Title GENE EXPRESSION ANALYSIS OF MUC5AC AND CDHI IN BPIFB1 TRANSFECTED AND NON-TRANSFECTED GASTRIC CANCEL CELL LINES, (External Examiner)
  44. (2019) The title of the project is DEVELOPMENT OF MONOLITHIC SILICA REVERSED PHASE HPLC COLUMN , (External Examiner)
  45. (2019) Dental research and Management , (editorial board member )
  46. (2019) reviewer of Substance Use and Misuse , (Reviewer)
  47. (2019) Reviewer of Oral Diseases, (Reviewer)
  48. (2019) reviewer for BMC Complementary and Alternative Medicine, (Reviewer)
  49. (2019) Reviewer for Journal of Taibah University Medical Sciences , (Reviewer)
  50. (2016) Reviewer for BMJ Case Reports, (Reviewer)
  51. (2015) MALAYSIAN DENTAL JOURNAL, (Reviewer)
  52. (2014) ANNAL OF DENTISTRY , (Reviewer)
  53. (2014) BIOMED RESEARCH INTERNATIONAL, (Reviewer)
  54. (2014) MEDICAL SCEINCE@OMICSONLINE.ORG, (Reviewer)
  55. (2014) BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, (Reviewer)
  56. (2014) DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, (Reviewer)
  57. (2013) Panel for Health and Translation Medicine (HTM) Research Publication Unit, (PANEL)
  58. (2013) Examiner for MBEB 4180 Research Project in Biomedical Science, (Internal Examiner)
Contribution to external organisation
  1. (2024) UKM Postgraduate Programme (Master and Phd)- External Assesor, National, (Expert Advisor)
  2. (2020) Proteomic expertise, Universiti Sain Malaysia, National
  3. (2020) Biosensor expertise , UniMap, National
  4. (2020) Technical sharing on Proteomics and genomics , INFORMM, Universiti Sains Malaysia
  5. (2019) antibacterial and toxicity screening , Kyocera, and facalabo, Japan
  6. (2019) Editorial board , Dental research and Management
  7. (2019) external examiner for UiTM, UiTM, Shah Alam
  8. (2013) PROJECT COLLABORATOR, NATIONAL UNIVERSITY HOSPITAL AND NATIONAL UNIVERSITY OF SINGAPORE, International
  9. (2013) Technical Consultant, Genexis Biotechnology
Contribution to event
  1. (2022) Participate in Webinar On " Salivary Theranostics, University, (Participant)
  2. (2022) Webinar On Opmd, University, (Participant)
  3. (2022) Webinar On "The Digitalization of Dental Case Management", University, (Participant)
  4. (2022) Penyelaras Program Saintifik (UM) Penyelaras Keseluruhan, University, (Event Coordinator)
  5. (2022) Participate, International, (Participant)
  6. (2022) Participate in Webinar Entitled Cancer of Nose- What You Need to Know, University, (Participant)
  7. (2022) Participate, University, (Participant)
  8. (2022) Participate in Msmbb, National, (Participant)
  9. (2021) Main Committee Member for The Event, International, (Event Organiser)
  10. (2021) Participant, National, (Participant)
  11. (2021) AJK & Ajkk Persidangan Saintifik Ke 22, National, (Event Coordinator)
  12. (2021) AJK Persidangan Saintifik Ke 22, University, (Event Coordinator)

SUPERVISION

Under Graduate Students
  1. (2023) The implications on dental students' mental well being/health with the magical word 'REDO' while in dental clinics
  2. (2023) The effects of probiotics supplements in individual with poor oral health (with halitosis) : a comparative proteomic approach.
  3. (2023) The effects of probiotics supplements in individuals with poor oral health (with halitosis) : a comparative proteomic approach.
  4. (2023) PROTEOME ANALYSIS OF BOESENBERGIA ROTUNDA EXTRACTLOADED PLGA NANOPARTICLE AGAINST ORAL CANCER
  5. (2023) Identification of host-immune response protein candidates in sera of lung cancer patients
  6. (2023) Conformation of serum biomarkers for early detection of OSCC
  7. (2022) PROTEOME ANALYSIS OF BOESENBERGIA ROTUNDA EXTRACTLOADED PLGA NANOPARTICLE AGAINST ORAL CANCER
  8. (2022) Identification of host-immune response protein candidates in sera of lung cancer patients
  9. (2022) CAN PROBIOTICS SIGNIFICANTLY IMPROVE DENTAL HYGIENE?
  10. (2022) "Confirmation of serum biomarkers for early detection of oral squamous cell carcinoma"
  11. (2014) DETECTION OF HOST-IMMUNE RESPONSE PROTEINS CANDIDATES IN SERA OF PATEINTS WITH PERIODONTITIS
  12. (2013) PREVELENCE OF HPV AND EPV VIRUS AMONG ORAL SQUAMOUS CELL CARCINOMA PATIENTS
  13. (2012) Detection of Host-Specific Immunogenic Proteins in the Saliva of Patients with Oral Squamous Cell Carcinoma
Postgraduate Student
PhD/ Doctoral
  1. (2024) IN VITRO ANTIPROLIFERATIVE EFFECT OF MALABARICONE C AGAINST ORAL SQUAMOUS CELL CARCINOMA, GOH PEI CHUNG
  2. (2023) Identification of Phytomedical properties in herbs, HEMAGIRRI A/P MANISEKARAN (Universiti Sains Malaysia (USM))
  3. (2023) Fabrication of High-performance hand-held Sensing System for clinical Biomarker analysis, lim Jia Chun (Universiti Malaysia Perlis (Unimap))
  4. (2023) A RESEARCH ON THE REGULATION MECHANISM OF EXOSOMAL MICRORNA-1275 EDIATED TREGSIN PROMOTING HEPATOCARCINOMA IMMUNE ESCAPE, Yang Jun (Universiti Teknologi MARA (UiTM))
  5. (2022) Parkinson's disease protein biomarkers detection: Faradic & non-faradic sensing, Hussaini Adam (Universiti Malaysia Perlis (Unimap))
  6. (2022) Isolation Of Anti-Inflammatory Metabolites from Endophytic Fungi Isolated From Jordanian Medicinal Plants, Tumallah Heba Mohammad Nabhan (Universiti Sains Malaysia (USM))
  7. (2022) Construction of suckling mice model of Coxsackievirus A9 Infection for pathogenesis study, DAN HANLIANG (Universiti Teknologi MARA (UiTM))
  8. (2022) Oral Pathology (ral squamous cell carcinoma in Libya (survival analysis, risk factors and Validation of potential biomarker panels) ), Laila Mustafa
  9. (2021) Study on the antiaging activity of Polyalthia longifolia polyphenolics (Sonn.) Thwaites in Saccharomyces cerevisiaeBY611 yeast cells and its underlying molecular mechanism, HEMAGIRRI AP MANISEKARAN (Universiti Sains Malaysia (USM))
  10. (2021) Identification of Phytomedical properties in herbs, Hemagirri AP Manisekaran (Universiti Sains Malaysia (USM))
  11. (2021) Faradaic and non-Faradaic Biosensing of Amyloid Fibrils Formation for Parkinson's Disease by Gold Interdigitated Electrode, Hussaini Adam (Universiti Malaysia Perlis (Unimap))
  12. (2020) A RESEARCH ON THE REGULATION MECHANISM OF EXOSOMAL MICRORNA-1275 EDIATED TREGSIN PROMOTING HEPATOCARCINOMA IMMUNE ESCAPE, Yang Jun (Universiti Teknologi MARA (UiTM))
  13. (2019) IDENTIFICATION OF GLYCOSYLATED PROTEINS EXPRESSION PATTERN IN ORAL SQUAMOUS CELL CARCINOMA, WONG YIN LING
  14. (2019) Gold Nanostructures in Mediating High-performance Medical Diagnosis of Human Blood Disease Biomarkers", lswary AP Letchumanan
  15. (2019) IDENTIFICATION OF POTENTIAL BIOMARKERS OF ORAL SQUAMOUS CELL CARCINOMA USING INTEGRATED PROTEOMICS AND GLYCOPROTEOMICS ANALYSES, WONG YIN LING
  16. (2017) DISCOVERY OF POTENTIAL BIOMARKERS IN ORAL SQUAMOUS CELL CARCINOMA USING NEXT GENERATION SEQUENCING AND PROTEOMIC TECHNOLOGIES, JESINDA PAULINE A/P KERISHNAN
  17. (2017) GENERATION OF CELL AND EXOSOME HYBRIDIZED APTAMERS FOR CANCER DIAGNOSIS AND THERAPY, PHANG WAI MEI
  18. (2017) DISCOVERY OF POTENTIAL BIOMARKERS IN ORAL SQUAMOUS CELL CARCINOMA USING NEXT GENERATION SEQUENCING AND PROTEOMIC TECHNOLOGIES, JESINDA PAULINE A/P KERISHNAN
  19. (2016) GENERATION OF CELL AND EXOSOME HYBRIDIZED APTAMERS FOR CANCER DIAGNOSIS AND THERAPY, PHANG WAI MEI
  20. (2014) Anticancer ACtivity on Goniothalamin on Oral Cancer Cells In Vitro and In Vivo, Fahme Abdul Kalk Saeed Kaid
  21. (2014) COMPREHENSIVE GENOMIC ANALYSIS OF UNKNOWN NONTUBERCULOSIS MYCOBACTERIUM ISOLATES, WONG GUAT JAH
  22. (2013) IDENTIFICATION OF POTENTIAL BIOMARKERS IN ORAL SQUAMOUS CELL CARCINOMA USING INTEGRATED PROTEOMICS AND GLYCOPROTEOMICS ANALYSES, Wong Yin Ling
  23. (2013) Discovery of Potential Biomarkers in Oral Squamous Cell Cacinoma using Nect Generation Sequencing Technology, Jesinda Pauline A/P Kerishnan
  24. (2013) COMPREHENSIVE GENOMIC ANALYSIS OF UNKNOWN NONTUBERCULOSIS MYCOBACTERIUM ISOLATES, WONG GUAT JAH
  25. (2010) Identification and Characterization of Protein Markers and Development of Immunoassay for The Detection of Hydatid Cyst Disease, Zohreh Kazemi Moghadam Kakhki (Universiti Sains Malaysia (USM))
  26. (2009) Identification of N- and O-Glycosylated Proteins Expressed in Human and Mice Breast Cancer Using Cell Line and Animal Model, Tan Aik Aun (Universiti Sains Malaysia (USM))
  27. (2008) Identification of N- and O-Glycosylated Proteins Expressed in Human and Mice Breast Cancer using Cell Line and Animal Model-, TAN AIK AUN (M0100104)
  28. (2008) Evaluation of In Vitro Cytotoxic Activity of Ocimum Basilicum and Mentha Spicata Extracts, Jegathambigai Rameshwar Naidu (Universiti Sains Malaysia (USM))
  29. (2008) Construction Of Recombinant BCG Expressing The VP1 Antigen Of Enterovirus 71 For The Development Of A Candidate Vaccine, Nurulhasanah Binti Othman (Universiti Sains Malaysia (USM))
  30. (2006) Detection And Identification Of Circulating Toxoplasma Gondii Antigens And Host Specific Proteins In Toxoplasmosis Via Serum Proteomic Approach, Emelia Binti Osman (Universiti Sains Malaysia (USM))
Master
  1. (2024) ELUCIDATION OF SURFACE PROTEINS FROM PLASMA-DERIVED EXOSOMES AS NOVEL BIOMARKERS FOR LUNG CANCER EARLY DETECTION, SAFIAH SAKINAH BINTI RAMLI @ MD SHAH
  2. (2011) Proteomic Analyses of Human Monocyte-Derived Macrophages Following Infection with Mycobacterium Tuberculosis, Nur Shuhaidatul Sarmiza Binti Abdul Halim (Universiti Sains Malaysia (USM))
  3. (2011) Identification of Immunogenic Protein(s) from Sera of Individuals Infected by Plasmodium Knowlesi, Chan Choon Keat (Universiti Sains Malaysia (USM))
  4. (2011) Epstein-Barr Virus Latent Membrane Protein 1 (LMP-1) Expression and Its Association with Expression of DNA Damage Repair Proteins in Nasopharyngeal Carcinoma (NPC)- An Evaluation, Yu Wei Chiuen (Universiti Sains Malaysia (USM))
  5. (2009) Detection of Host-Specific Immunogenic Proteins in The Sera of Oral Squamous Cell Carcinoma (OSCC) Patients, Siti Nuraishah Binti Azman (Universiti Sains Malaysia (USM))
  6. (2008) Detection of Host-specific Immunogenic Proteins in the Sera of Oral Squamous Cell Carcinoma (OSCC) Patients, Siti Nuraishah Azman (Universiti Sains Malaysia (USM))

TEACHING

Master
  1. (2016) DPGA6107 - Research Methodology & Computer Literacy
  2. (2015) DPGA6107 - Research Methodology & Computer Literacy
Bachelor
  1. (2024) MIC3007 - Cancer Biology
  2. (2023) MIC3007 - Cancer Biology
  3. (2023) GDD0004 - Dental Health
  4. (2022) NA - Competency in Oral Medicine
  5. (2022) PBL 2.1 - Lifelong Learning and Information Management
  6. (2022) MIC3007 - Cancer Biology
  7. (2022) GDD0004 - Dental Health
  8. (2021) PBL - 2.1
  9. (2021) GDD0004 - Dental Health
  10. (2021) GID1001 - Oral Health
  11. (2021) PBL - Ummp Block 9 Renal
  12. (2020) GID1001 - Oral Health
  13. (2020) GID1001 - Oral Health
  14. (2020) PBL 2-1 - Problem-Based Learning Module: Generic Life Long Learning and Information Management
  15. (2019) GID1001 - Oral Health
  16. (2019) PBL 2-1 - Problem-Based Learning Module: Generic Life Long Learning and Information Management
  17. (2018) GID1001 - Oral Health
  18. (2018) MIC3007 - Cancer Biology
  19. (2017) MIC3007 - Cancer Biology
  20. (2016) GID1001 - Oral Health
  21. (2016) GID1001 - Kesihatan Mulut (Oral Health)
  22. (2016) PBL4.1 - Generic: Entrepreneurship Skill
  23. (2013) PBL - Entrepreneurship
  24. (2012) PBL - Problem Based Learning

SOCIAL RESPONSIBILITY ACTIVITIES

  • Volunteer Umhacks 1 Was a Collaboration Project by The University Malaya Dental Education Enhancement and Development (Umdeed) Unit, (01 May 2021 - 31 May 2021) (University)
  • Contribution in Umdeed Activities, (15 Apr 2021 - 30 Jun 2021) (University)
  • Umhakcs 3.0 (2020), (01 Sep 2020 - 03 Sep 2020)
  • Pa & Ma Superkids Fiesta 2019, (01 Nov 2019 - 03 Nov 2019)