ARTICLE IN ACADEMIC JOURNALS
| NO | DETAILS OF ARTICLE IN ACADEMIC JOURNALS |
|---|---|
| 1. |
Computational Elucidation of Hub Genes and Pathways Correlated with the Development of 5-Fluorouracil Resistance in HCT 116 Colorectal Carcinoma Cell Line
2026
Author(s) : Lim Siew Huah, Sim Kae Shin Source :
BIOCHEMICAL GENETICS
DOI :
10.1007/s10528-025-11041-2
|
| 2. |
Ethnobotanical and alkaloid composition with their cytotoxicity of Tabernaemontana polyneura: A review with in silico ADMET analysis
2025
Author(s) : Lim Siew Huah, Sim Kae Shin Source :
FITOTERAPIA
DOI :
10.1016/j.fitote.2025.106851
|
| 3. |
Phytochemical Profiling, Biological Activities, and Molecular Docking Studies of Essential Oils from <i>Ziziphus leucodermis</i> (Baker) O. Schwartz
2025
Author(s) : Lim Siew Huah Source :
CHEMISTRY & BIODIVERSITY
DOI :
10.1002/cbdv.202500434
|
| 4. |
Investigation of cytotoxic indoleninyl-thiobarbiturate zwitterions as DNA targeting agents
2025
Author(s) : Lim Siew Huah, Sim Kae Shin Source :
JOURNAL OF MOLECULAR STRUCTURE
DOI :
10.1016/j.molstruc.2024.140278
|
| 5. |
In vitro anti-neovascularization and anti-angiogenic activities of<i> Platycladus</i><i> orientalis</i> (L.) Franco in human retinal endothelial cells via Raf/MEK 1/2 and AKT1/mTOR signaling
2025
Author(s) : Lim Siew Huah Source :
LIFE SCIENCES
DOI :
10.1016/j.lfs.2025.124017
|
| 6. |
Ethnobotanical and alkaloid composition with their cytotoxicity of <i>Tabernaemontana polyneura</i>: A review with <i>in silico</i> ADMET analysis (vol 186, 106851, 2025)
2025
Author(s) : Lim Siew Huah, Sim Kae Shin Source :
FITOTERAPIA
DOI :
10.1016/j.fitote.2025.106869
|
| 7. |
The Tiger Milk Medicinal Mushroom<i> Lignosus</i><i> rhinocerus</i> (Agaricomycetes) Mitigates Oxidative Damage in a Cellular Model Mimicking Friedreich's Ataxia
2025
Source :
INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS
|
| 8. |
Computational and <i>In vitro</i> Elucidation of Indolenine-barbituric Acid Zwitterions as Potential Chemotherapeutical Agents
2024
Author(s) : Lim Siew Huah, Sim Kae Shin Source :
LETTERS IN DRUG DESIGN & DISCOVERY
DOI :
10.2174/0115701808279494231206060106
|
| 9. |
Safety profile of subacute oral administration of ethanolic extract of <i>Gracilaria manilaensis</i> Yamamoto & Trono
2024
Source :
JOURNAL OF APPLIED PHYCOLOGY
DOI :
10.1007/s10811-024-03218-w
|
| 10. |
<i>In</i><i> vitro</i> anti-inflammatory activity and molecular docking of<i> Peperomia</i><i> pellucida</i> (L.) Kunth extract via the NF-κB and PPAR-γ signalling in human retinal pigment epithelial cells
2024
Source :
BIOORGANIC CHEMISTRY
DOI :
10.1016/j.bioorg.2024.107969
|
| 11. |
Quinoline, Indole, and Isogranatanine Alkaloids from Malayan <i>Leuconotis eugeniifolia</i>
2024
Source :
JOURNAL OF NATURAL PRODUCTS
DOI :
10.1021/acs.jnatprod.3c00960
|
| 12. |
<i>Peperomia pellucida</i> (L.) <sc>Kunth</sc> suppresses glycation-induced inflammatory response in human retinal pigment epithelial cell line ARPE-19 via JAK-STAT3 signaling
2024
Author(s) : Lim Siew Huah Source :
ARCHIV DER PHARMAZIE
DOI :
10.1002/ardp.202400299
|
| 13. |
Yunnanensine type indole and<i> seco</i> stemmadenine-yunnanensine type bisindole alkaloids from the bark of Alstonia scholaris
2024
Author(s) : Lim Siew Huah, Low Yun Yee Source :
PHYTOCHEMISTRY LETTERS
DOI :
10.1016/j.phytol.2024.04.003
|
| 14. |
Polyneurines A-H, iboga alkaloids from Tabernaemontana polyneura
2023
Source :
PHYTOCHEMISTRY
DOI :
10.1016/j.phytochem.2023.113587
|
| 15. |
Synthesis and crystal structure of dimethyl 2,2'-(2,5-bis(4-hydroxyphenyl)-2,5-dihydrofuran-3,4-diyl)dibenzoate, C<sub>34</sub>H<sub>30</sub>O<sub>7</sub>
2023
Author(s) : Lim Siew Huah, Low Yun Yee Source :
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES
DOI :
10.1515/ncrs-2022-0469
|
| 16. |
Chippiine, iboga, cleavamine, vobasine, and cytotoxic bisindole alkaloids from <i>Tabernaemontana polyneura</i>
2023
Source :
TETRAHEDRON
DOI :
10.1016/j.tet.2023.133706
|
| 17. |
Eugeniifoline, a Pentacyclic Indole Alkaloid from Leuconotis eugeniifolia, and Configurational Revision of Synthetic Eugeniifoline Isolated from a Diversity-Enhanced Extract
2023
Source :
JOURNAL OF NATURAL PRODUCTS
DOI :
10.1021/acs.jnatprod.2c00731
|
| 18. |
Artocarpus heterophyllus Lam. Stem Bark Inhibits Melanogenesis through Regulation of ROS, cAMP, and MAPK Pathways
2023
Source :
SAINS MALAYSIANA
DOI :
10.17576/jsm-2023-5202-10
|
| 19. |
Malaysian brown macroalga Padina australis mitigates lipopolysaccharide-stimulated neuroinflammation in BV2 microglial cells
2023
Author(s) : Wong Kah Hui, Lim Siew Huah Source :
IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES
DOI :
10.22038/IJBMS.2023.67835.14842
|
| 20. |
Adenosine Improves Mitochondrial Function and Biogenesis in Friedreich's Ataxia Fibroblasts Following L-Buthionine Sulfoximine-Induced Oxidative Stress
2023
Author(s) : Rozaida @ Poh Yuen Ying, Wong Kah Hui, Lim Siew Huah, Syarifah Nur Binti Syed Abdul Rahman Source :
BIOLOGY-BASEL
DOI :
10.3390/biology12040559
|
| 21. |
Extraction of phytochemicals with health benefit from Peperomia pellucida (L.) Kunth through liquid-liquid partitioning
2022
Author(s) : Umah Rani A/p Kuppusamy, Lim Siew Huah Source :
JOURNAL OF APPLIED RESEARCH ON MEDICINAL AND AROMATIC PLANTS
DOI :
10.1016/j.jarmap.2022.100392
|
| 22. |
Arboduridine, a hexacyclic caged monoterpenoid indole incorporating cyclohexane, piperidine, and bridged-fused pyrrolidine-tetrahydrofuran moieties
2022
Author(s) : Lim Siew Huah, Low Yun Yee Source :
TETRAHEDRON LETTERS
DOI :
10.1016/j.tetlet.2022.153836
|
| 23. |
Vobasine, vincamine, voaphylline, tacaman, and iboga alkaloids from Tabernaemontana corymbosa
2022
Author(s) : Lim Siew Huah, Low Yun Yee Source :
PHYTOCHEMISTRY
DOI :
10.1016/j.phytochem.2022.113384
|
| 24. |
Comparative Analysis of In Vitro Enzyme Inhibitory Activities and Phytochemicals from Platycladus orientalis (L.) Franco via Solvent Partitioning Method
2022
Author(s) : Sarni Binti Mat Junit, Lim Siew Huah Source :
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
DOI :
10.1007/s12010-022-03921-9
|
| 25. |
Carrageenophyte Kappaphycus malesianus Inhibits Microglia-Mediated Neuroinflammation via Suppression of AKT/NF-kappa B and ERK Signaling Pathways
2022
Author(s) : Wong Kah Hui, Lim Siew Huah Source :
MARINE DRUGS
DOI :
10.3390/md20080534
|
| 26. |
Antiproliferative and Microtubule-stabilizing Activities of Two Iboga-vobasine Bisindoles Alkaloids from Tabernaemontana corymbosa in Colorectal Adenocarcinoma HT-29 Cells
2022
Author(s) : Lim Siew Huah, Sim Kae Shin, Gokula Mohan A/l Duchiyanda Mohan, Taznim Begam Binti Mohd Mohidin, Low Yun Yee Source :
PLANTA MEDICA
DOI :
10.1055/a-1755-5605
|
| 27. |
Spirulina platensis Suppressed iNOS and Proinflammatory Cytokines in Lipopolysaccharide-Induced BV2 Microglia
2022
Source :
METABOLITES
DOI :
10.3390/metabo12111147
|
| 28. |
Therapeutic Potential of Complementary and Alternative Medicines in Peripheral Nerve Regeneration: A Systematic Review
2021
Source :
CELLS
DOI :
10.3390/cells10092194
|
| 29. |
GRACILARIA MANILAENSIS YAMAMOTO & TRONO EXTRACTS IN ATTENUATION OF LIPOPOLYSACCHARIDE-STIMULATED NEUROINFLAMMATION IN BV2 MICROGLIA
2021
Author(s) : Wong Kah Hui, Lim Siew Huah Source :
PHYCOLOGIA
|
| 30. |
Evaluation of anti-melanogenesis and free radical scavenging activities of five Artocarpus species for cosmeceutical applications
2021
Source :
INDUSTRIAL CROPS AND PRODUCTS
DOI :
10.1016/j.indcrop.2020.113184
|
| 31. |
The Bisindole Alkaloids Angustilongines M and A from Alstonia penangiana Induce Mitochondrial Apoptosis and G0/G1 Cell Cycle Arrest in HT-29 Cells through Promotion of Tubulin Polymerization
2021
Source :
JOURNAL OF NATURAL PRODUCTS
DOI :
10.1021/acs.jnatprod.1c00013
|
| 32. |
Arbolodinines A-C, biologically-active aspidofractinine-aspidofractinine, aspidofractinine-strychnan, and kopsine-strychnan bisindole alkaloids from Kopsia arborea
2021
Source :
TETRAHEDRON
DOI :
10.1016/j.tet.2020.131802
|
| 33. |
UNRAVELLING THE ANTI-NEUROINFLAMMATORY ACTIVITY OF THE MALAYSIAN RED MACROALGA KAPPAPHYCUS MALESIANUS IN LIPOPOLYSACCHARIDES-STIMULATED BV2 MICROGLIA
2021
Author(s) : Wong Kah Hui, Lim Siew Huah Source :
PHYCOLOGIA
|
| 34. |
Evaluation of DNA Binding and Topoisomerase I Inhibitory Activities of 16 '-Decarbomethoxydihydrovoacamine from Tabernaemontana corymbosa
2020
Source :
CHEMISTRYSELECT
DOI :
10.1002/slct.202004153
|
| 35. |
Discovering the Potentials of Medicinal Mushrooms in Combating Depression - A Review
2020
Author(s) : Wong Kah Hui, Lim Siew Huah Source :
MINI-REVIEWS IN MEDICINAL CHEMISTRY
DOI :
10.2174/1389557520666200526125534
|
| 36. |
Neuroprotective effects of Hericium erinaceus (Bull.: Fr.) Pers. against high-dose corticosterone-induced oxidative stress in PC-12 cells
2020
Author(s) : Wong Kah Hui, Lim Siew Huah Source :
BMC COMPLEMENTARY MEDICINE AND THERAPIES
DOI :
10.1186/s12906-020-03132-x
|
| 37. |
Macroline, talpinine, and sarpagine alkaloids from Alstonia penangiana. An NMR-based method for differentiating between A. penangiana and A. macrophylla
2020
Source :
PHYTOCHEMISTRY
DOI :
10.1016/j.phytochem.2020.112391
|
| 38. |
Malaysian macroalga Padina australis Hauck attenuates high dose corticosterone-mediated oxidative damage in PC12 cells mimicking the effects of depression
2020
Source :
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
|
| 39. |
Malaysian macroalga Padina australis Hauck attenuates high dose corticosterone-mediated oxidative damage in PC12 cells mimicking the effects of depression
2020
Source :
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
DOI :
10.1016/j.sjbs.2020.04.042
|
| 40. |
Influence of ortho- and meta-substituted N-heterocyclic dications towards the self-assembly of p-sulfonatocalix[4]arene
2020
Author(s) : Lim Siew Huah Source :
CRYSTENGCOMM
DOI :
10.1039/c9ce01410a
|
| 41. |
Lycopodium Alkaloids: Lycoplatyrine A, an Unusual Lycodine-Piperidine Adduct from Lycopodium platyrhizoma and the Absolute Configurations of Lycoplanine D and Lycogladine H
2019
Source :
JOURNAL OF NATURAL PRODUCTS
DOI :
10.1021/acs.jnatprod.8b00754
|
| 42. |
A Cytotoxic Indole Characterized by Incorporation of a Unique Carbon-Nitrogen Skeleton and Two Pentacyclic Corynanthean Alkaloids Incorporating a Substituted Tetrahydrofuranone Ring from Kopsia arborea
2019
Source :
JOURNAL OF NATURAL PRODUCTS
DOI :
10.1021/acs.jnatprod.9b00255
|
| 43. |
Conolodinines A-D, Aspidosperma-Aspidosperma Bisindole Alkaloids with Antiproliferative Activity from Tabernaemontana corymbosa
2019
Source :
JOURNAL OF NATURAL PRODUCTS
DOI :
10.1021/acs.jnatprod.8b00919
|
| 44. |
A Cytotoxic Indole Characterized by Incorporation of a Unique Carbon-Nitrogen Skeleton and Two Pentacyclic Corynanthean Alkaloids Incorporating a Substituted Tetrahydrofuranone Ring from Kopsia arborea
2019
Source :
JOURNAL OF NATURAL PRODUCTS
|
| 45. |
Conolodinines A-D, Aspidosperma-Aspidosperma Bisindole Alkaloids with Antiproliferative Activity from Tabernaemontana corymbosa
2019
Source :
JOURNAL OF NATURAL PRODUCTS
|
| 46. |
Macroline-Sarpagine Bisindole Alkaloids with Antiproliferative Activity from Alstonia penangiana
2019
Source :
JOURNAL OF NATURAL PRODUCTS
|
| 47. |
Lycopodium Alkaloids: Lycoplatyrine A, an Unusual Lycodine-Piperidine Adduct from Lycopodium platyrhizoma and the Absolute Configurations of Lycoplanine D and Lycogladine H
2019
Source :
JOURNAL OF NATURAL PRODUCTS
|
| 48. |
Macroline-Sarpagine Bisindole Alkaloids with Antiproliferative Activity from Alstonia penangiana
2019
Source :
JOURNAL OF NATURAL PRODUCTS
DOI :
10.1021/acs.jnatprod.9b00712
|
| 49. |
Ajmaline, Oxindole, and Cytotoxic Macroline-Akuammiline Bisindole Alkaloids from Alstonia penangiana
2018
Source :
JOURNAL OF NATURAL PRODUCTS
DOI :
10.1021/acs.jnatprod.8b00170
|
| 50. |
Biologically active vallesamine, strychnan, and rhazinilam alkaloids from Alstonia: Pneumatophorine, a nor-secovallesamine with unusual incorporation of 3-ethylpyridine moiety
2015
Author(s) : Lim Siew Huah Source :
Phytochemistry
|
| 51. |
Ibogan, tacaman, and cytotoxic bisindole alkaloids from Tabernaemontana. Cononusine, an iboga alkaloid with unusual incorporation of a pyrrolidone moiety
2015
Author(s) : Lim Siew Huah Source :
Journal of Natural Products
|
| 52. |
Lumusidines A-D and villalstonidine F, macroline-macroline and macroline-pleiocarpamine bisindole alkaloids from Alstonia macrophylla
2013
Source :
Phytochemistry
|
| 53. |
Perhentidines A-C: macroline-macroline bisindoles from Alstonia and the absolute configuration of perhentinine and macralstonine.
2012
Author(s) : Lim Siew Huah Source :
Journal of Natural Products
|
| 54. |
Lumutinines A-D, linearly fused macroline-macroline and macroline-sapargine bisindole from Alstonia macrophylla
2011
Author(s) : Lim Siew Huah Source :
Journal of Natural Products
|
| 55. |
A cycloartane incorporating a fused tetrahydrofuran ring and a cytotoxic lactam from Monocarpia marginalis.
2008
Author(s) : Lim Siew Huah Source :
Journal of Natural Products
|
| 56. |
Leuconoxine, kopsinitarine, kopsijasmine, and kopsinone derivatives from Kopsia
2007
Author(s) : Lim Siew Huah Source :
Journal of Natural Products
|
RESEARCH PROJECT
| GRANT | PROGRESS | STATUS |
|---|---|---|
|
Alkaloid Investigation Of Melodinus Orientalis: Linking Chemistry To Malayan Folk Medicine
|
|
end |
|
Sustainable Synthesis Of The Cytotoxic Indole Alkaloid Valparicine And Investigation Of The Scope And Mechanism Of Antiproliferative Activity
|
|
end |
|
Chemical Investigations Of New And Biologically-active Secondary Metabolites From Selected Malaysian Apocunaceae (kopsia, Alstonia, Tabernaemontana)
|
|
end |
|
Alkaloid Variation In Malaysian Alstonia: Determination Of Variation Of Alkaloid Composition In A. Macrophylla As A Function Of Location
Researcher(s) : Associate Prof. Dr. Sim Kae Shin |
|
end |
|
Natural Product
|
|
end |
RESEARCH COLLABORATOR
| GRANT | PROGRESS | STATUS |
|---|---|---|
|
Advancing the Design and Synthesis of Ligands for the Detection and Extraction of Rare Earth Elements Using Machine Learning
|
|
new |
|
Elucidating Oxygen-resilient Nanozyme-embedded Hydrogel For Sustainable Electrocatalysis
Researcher(s) : Dr. Rozie Binti Sarip, Dr. Mehran Sookhakian, Associate Prof. Dr. Lim Siew Huah, Prof. Dr. Yatimah Binti Alias, Lee Pui Kee |
|
on going |
|
Environmental Sustainability of Spent Cold Brew Coffee Grounds for Cosmeceutical Applications
|
|
on going |
|
Revealing The Selected Indigenous Tropical Fruit Trees For Potential Skin-lightening Cosmeceutical Application
|
|
on going |
|
Elucidation Of The Therapeutic Role Of Medicinal Mushroom, Hericium Erinaceus (bull.: Fr.) Pers. In Spinocerebellar Ataxia Type 3 (sca3)
|
|
end |
|
Encapsulation Of Anti-melanogenesis Agents From Artocarpus Species: Mechanistic And In Vitro Release Studies
|
|
end |
|
1. Deep Eutectic Solvent As Potential Media In Designing Metal Organic Frameworks 2. Realization Of Flexible Paper-based Sensor Utilizing 2d Transition Metal Chalcogenide
Researcher(s) : Associate Prof. Dr. Lim Siew Huah, Piyarat Nimmanpipug, Apinpus Rujiwatra |
|
end |
|
Reactivity Of Anodically Generated Stilbene Cation Radicals: The Effect Of Ortho Substitution By Hydroxymethyl, Aminomethyl, And Carboxylic Acid Groups
Researcher(s) : Associate Prof. Dr. Lim Siew Huah, Prof. Dr. Kam Toh Seok |
|
end |
|
Biological Studies Of Synthetic Compounds (bisbenzopyrans, Bisbenzofurans, Oxocines, And Structural Analogs) And Natural Compounds (indole And Bisindole Derivatives) For Reversal Of Multidrug Resistance And Antiproliferative Activity Against Human Cancer Cells
Researcher(s) : Prof. Dr. Kam Toh Seok, Associate Prof. Dr. Lim Siew Huah |
|
end |