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Dr. Saharuddin bin Mohamad received his Bachelor of Engineering (Bioengineering) in 1998 and Master of Engineering (Bioengineering) in 2000 from the University of Tokushima, Japan. He successfully completed his Doctor of Engineering degree in functional system engineering in 2003 at the same university. Then, he took up a post-doctoral position in bioinformatics at Nara Institute of Science and Technology (NAIST), Japan until 2004.  He was appointed as lecturer in Bioinformatics Program, Institute of Biological Sciences, Faculty of Science, University of Malaya ever since.

His research interest focuses on structural bioinformatics, with special interest in computer-aided drug design and protein engineering. He also engages in molecular bioinformatics research projects related to analysis and data mining of the Next Generation Sequencing (NGS) data in genomics, metagenomics, whole-exomic and trancriptomics. Furthermore, he involves in translational bioinformatics research projects with his collaborators from Institute of Medical Research, Malaysia.

He actively involves in teaching and development of courses for Bachelor of Science (Bioinformatics) and Master of Bioinformatics at the University of Malaya. He served as Programme Coordinator for Bachelor of Science (Bioinformatics) Degree Program from 2013 to 2014 and re-appointed as the coordinator from 2019 to 2020. He was appointed as Advisory Board Member of MyBioInfoNet (Malaysia Bioinformatics Network) for 2019-2021 session. He was elected as vice president of the Malaysian Society of Bioinformatics and Computational Biology (MaSBiC) for 2018-2020 and 2020-2022 session. He was appointed as the Head of Institute of Biological Sciences, Faculty of Science from January 2020 to January 2022.  Currently, he serves as the Head of Centre of Research in Systems Biology, Structural, Bioinformatics and Human Digital Imaging (CRYSTAL), University of Malaya since 2017.