Dr. Aslina Pahrudin Arrozi is a Senior Lecturer in the Department of Molecular Medicine, Faculty of Medicine, Universiti Malaya, where she leads a translational research program at the intersection of molecular neuropharmacology, neuroinflammation, cellular bioenergetics, and cognitive health across the human lifespan. She earned her BSc in Biochemistry (2013) and Master’s in Medical Science (2018) from Universiti Kebangsaan Malaysia (UKM), followed by a PhD in Medical Science (2022) from Shiga University of Medical Science (SUMS), Japan, as a MEXT Scholar. Prior to her current appointment at Universiti Malaya in late 2023, she served as an Assistant Professor at the SUMS Molecular Neuroscience Research Centre.
Her research addresses brain health across the lifespan, focusing primarily on the molecular pathology of neurodegeneration and the development of natural product-based neurotherapeutics. Her research programme centers on evaluating natural bioactive compounds including Zingiber rhizome extracts, vitamin E isomers (tocopherols and tocotrienols), and bioactive peptides to target key pathological drivers of neurodegeneration (Alzheimer’s disease and related tauopathies). Specifically, she investigates how these natural agents modulate neuroinflammation, microglial and glial activation, oxidative stress, mitochondrial bioenergetic failure, and the toxic accumulation of amyloid-beta and tau proteins.
Grounded in biochemistry, molecular neuroscience, and cellular pathology, her expertise integrates advanced in vitro disease modeling, mitochondrial bioenergetics, cellular stress pathways (including TXNIP and NF-kB signaling), and functional neuro-assessments such as Electroencephalography (EEG). By mapping the complex interplay between systemic metabolic signals, neuroinflammatory cascades, and organelle dysfunction, her work establishes a robust translational platform to discover neuroprotective interventions and diagnostic biomarkers. Dr. Aslina actively collaborates across disciplines with natural product chemists, bioengineers, data scientists, and clinical neuroscientists to translate mechanistic biochemical insights into targeted neurotherapeutic strategies for age-related neurodegenerative disorders and lifespan cognitive health.