Dr Mas Ayu is an Epidemiologist in the Department of Social and Preventive Medicine, Faculty of Medicine, University of Malaya. She is also a consultant epidemiologist at the University Malaya Medical Centre. Her research interest focuses on mental health, substance abuse and psychopharmacology, especially the side effect of metabolic syndrome due to the treatment of schizophrenia. A recipient of several research grants, she has many collaborative research activities with University Malaya Centre of Addiction Sciences. Her recent project is Enhancing Quality and Longevity of Life of Malaysian B40 under Long Term Research Grant Scheme (LRGS). She also involved in another project for B40 - Coping to Live with COVID-19: The New Norm which was funded by WHO.  

As a public health specialist in infectious disease and field epidemiologist, Dr Mas Ayu is the member of Malaysia One Health University Network (MyOHUN) which is part of USAID. She is active in activity related to One Health in Malaysia and Southeast Asia Region. Dr Mas Ayu also has research interest on communicable diseases mainly focusing on vector borne diseases like Chikungunya and Dengue Fever. She has research collaboration through Malaysia-Sweden Research Link with Umea University, working on the early warning system of dengue outbreak. 

Dr Mas Ayu attended the evidence-based medicine (EBM) practice workshop as training for trainer in Oxford University in 2008, funded by grants from the European Union. The international collaboration was together with Utrecht (UMCU), Centre for Evidence-Based Medicine (CEBM), University of Oxford, the Rumah Sakit Cipto Mangunkusumo (RSCM) Hospital, Jakarta and University of Malaya. She has conducted several EBM workshops together with other trainers. She also served as panel for The Malaysian Qualifications Agency (MQA), which is a statutory body in Malaysia to accredit academic programs provided by educational institutions providing post-secondary or higher education and facilitate the accreditation and articulation of qualifications.