PROF. DR. ALIMOHAMMAD SHARIFI
Department of Orthopaedic Surgery
Faculty of Medicine
alisharifium.edu.myView CV | |
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Biography | |
Prof. Ali Mohammad Sharifi is a scholar with over 27 years of experience in Molecular Pharmacology at the Iran University of Medical Sciences and currently joined as a professor of regenerative Medicine in the Tissue Engineering Group at NOCERAL, department of Orthopedics Surgery, School of Medicine. He obtained his Ph.D. from the University of Glasgow in 1992 and in 2018, he further enriched his expertise by acquiring a Tissue Banking Diploma from the National University of Singapore. Throughout his career, Prof. Sharifi has undertaken international research, including working at McGill University in Canada and at Max Plank Institute in Germany. His research output includes over 100 publications in high-impact journals, along with several patented innovations. He has held various administrative and editorial roles in academia, and has served as a peer reviewer for numerous high-impact journals. His dedication to education is evident through his mentorship of undergraduate and postgraduate students, particularly Ph.D. candidates specializing in molecular medicine, tissue engineering, molecular pharmacology, and cell therapy. Prof. Sharifi's research expertise involves the fields of cell therapy and regenerative Pharmacology, with a particular emphasis on translational medicine. His extensive body of work includes pioneering studies on pharmacological priming, therapeutic angiogenesis, and innovative strategies to enhance the effectiveness of stem cell therapy by manipulating HIF-1α stabilization, especially in the context of diabetes. Additionally, his research activities include bone and cartilage regeneration, employing a diverse array of strategies such as stem cells and biologically derived products like amniotic membrane extract and mesenchymal stem cell-derived secretome. He has also explored the potential of herbal agents in regenerative medicine. His contributions extend to the development of custom-made bio-implants for addressing large bone defects and the design and production of various wound dressings, with a specific focus on diabetic wound healing. In recent times, Prof. Sharifi has harnessed the transformative power of CRISPR gene editing technology to combat synovial fibrosis induced by osteoarthritis. In summary, Professor Sharifi is an active scientist in the field of Molecular Pharmacology and Regenerative Medicine, exemplifying innovation, and dedication to advancing scientific knowledge for improvement of healthcare and human well-being.
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Elucidating The Role And Mechanism Of The Hif-1? On Tgf?/alks/smads Axis In Human Fibroblast Like Synoviocyte To Combat Osteoarthritis Induced Synovial Fibrosis |
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on going |
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In-vitro and in-vivo evaluation of angiogenic potential of a novel lithium chloride loaded silk fibroin / alginate 3D porous scaffold with antibacterial activity, for promoting diabetic wound healing
Restoring the Angiogenic Capacity of the Human Diabetic Adipose-derived mesenchymal stem cells Primed with Deferoxamine as a Hypoxia Mimetic Agent: Role of HIF-1α
Biomimetic hybrid scaffold containing niosomal deferoxamine promotes angiogenesis in full-thickness wounds
Biomimetic hybrid scaffold containing niosomal deferoxamine promotes angiogenesis in full-thickness wounds
Redox signaling in regenerative medicine: Regulatory mechanisms and therapeutic implications