Hesham Al-Mekhlafi has a PhD in public health (2008), master’s degrees in medical science (parasitology) (2004) and in applied statistics (2012) as well as a bachelor’s degree in medical laboratories (1997). Since early 2000s, he has been actively engaged in research on the molecular epidemiology and prevention of infectious diseases including malaria, neglected tropical diseases, NTDs (such as soil-transmitted helminthiasis, schistosomiasis, leishmaniasis and dengue fever), and waterborne parasites. He joined the department of parasitology, University of Malaya (a regional leading dept. in parasitology research) for seven years (2009–2016) as a senior lecturer and promoted to associate professor. In 2016, he joined Jazan University, Saudi Arabia and promoted to full professor in 2022. He re-joined Universiti Malaya in 2023.

He has taught several courses in parasitology, epidemiology, biostatistics, and research methodology at undergraduate and postgraduate levels. He has established passionate research teams that involved diligent postgraduate students, enthusiastic colleagues, and inspiring national and international collaborators. The research dedicated to helping vulnerable rural and aboriginal communities in Malaysia and other countries including Yemen, Nigeria and Libya against the NTDs, malaria and other infectious diseases. He has published more than 150 articles in high-impact ISI & Scopus indexed journals; with h-index of 41 (WoS).

Hesham has been a member of several academic, scientific and administrative councils and committees. He also enjoys reviewing scientific manuscripts, research proposals, plans and strategies, theses and reports, etc. He is a member of the editorial boards of several renowned journals, and a regular reviewer for many peer-reviewed journals as well as a panel member of assessors for various national and international research grant schemes and postgraduate programs.