ARTICLE IN ACADEMIC JOURNALS
NO | DETAILS OF ARTICLE IN ACADEMIC JOURNALS |
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1. |
Exploring the potential of chromone scaffold compounds in cancer therapy: targeting key kinase pathways
2023
Author(s) : Leong Sze Wei Source : Medicinal Chemistry Research DOI : 10.1007/s00044-023-03063-5 |
2. |
Discovery of a novel dual functional phenylpyrazole-styryl hybrid that induces apoptotic and autophagic cell death in bladder cancer cells
2023
Author(s) : Leong Sze Wei Source : European Journal of Medicinal Chemistry DOI : 10.1016/j.ejmech.2023.115335 |
3. |
Curcumin-like diarylpentanoid analogues inhibit influenza A virus (H1N1) replication and pro-inflammatory cytokines production in A549 lung epithelial cells
2023
Author(s) : Leong Sze Wei Source : RESPIROLOGY |
4. |
Discovery of a novel dual functional phenylpyrazole-styryl hybrid that induces apoptotic and autophagic cell death in bladder cancer cells
2023
Author(s) : Leong Sze Wei Source : EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY DOI : 10.1016/j.ejmech.2023.115335 |
5. |
Discovery of a novel dual functional phenylpyrazole-styryl hybrid that induces apoptotic and autophagic cell death in bladder cancer cells
2023
Author(s) : Leong Sze Wei Source : EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY DOI : https://doi.org/10.1016/J.EJMECH.2023.115335 |
6. |
Exploring the potential of chromone scaffold compounds in cancer therapy: targeting key kinase pathways
2023
Author(s) : Leong Sze Wei Source : MEDICINAL CHEMISTRY RESEARCH DOI : https://doi.org/10.1007/s00044-023-03063-5 |
7. |
Flavonoid diversity and roles in the lipopolysaccharide-mediated inflammatory response of monocytes and macrophages
2023
Author(s) : Leong Sze Wei Source : Future Medicinal Chemistry |
8. |
Exploring the potential of chromone scaffold compounds in cancer therapy: targeting key kinase pathways
2023
Author(s) : Leong Sze Wei Source : MEDICINAL CHEMISTRY RESEARCH DOI : 10.1007/s00044-023-03063-5 |
9. |
In silico studies, nitric oxide, and cholinesterases inhibition activities of pyrazole and pyrazoline analogs of diarylpentanoids
2021
Author(s) : Leong Sze Wei Source : Archiv Der Pharmazie |
10. |
The involvement of l-arginine-nitric oxide-cgmp-atp-sensitive k+ channel pathway in antinociception of bbhc, a novel diarylpentanoid analogue, in mice model
2021
Author(s) : Leong Sze Wei Source : Molecules |
11. |
Antinociceptive activities of a novel diarylpentanoid analogue, 2-benzoyl-6-(3-bromo-4-hydroxybenzylidene)cyclohexen-1-ol, and its possible mechanisms of action in mice
2021
Author(s) : Leong Sze Wei Source : Scientific Reports |
12. |
Persistent Newcastle disease virus infection in bladder cancer cells is associated with putative pro-survival and anti-viral transcriptomic changes.
2021
Author(s) : Leong Sze Wei Source : BMC Cancer |
13. |
Cephalomannine inhibits hypoxia-induced cellular function via the suppression of APEX1/HIF-1α interaction in lung cancer
2021
Author(s) : Leong Sze Wei Source : Cell Death and Disease |
14. |
Development of diarylpentadienone analogues as alpha-glucosidase inhibitor: Synthesis, in vitro biological and in vivo toxicity evaluations, and molecular docking analysis
2020
Author(s) : Leong Sze Wei Source : Bioorganic Chemistry |
15. |
In-vitro and in-silico evaluations of heterocyclic-containing diarylpentanoids as Bcl-2 inhibitors against lovo colorectal cancer cells.
2020
Author(s) : Leong Sze Wei Source : Molecules |
16. |
Synthesis and in vitro biological evaluations of novel tetrapeptide as therapeutic agent for wound treatment
2020
Author(s) : Leong Sze Wei Source : Journal of Saudi Chemical Society |
17. |
Metallointercalator [Ru(dppz)2(PIP)]2+ Renders BRCA Wild-Type Triple-Negative Breast Cancer Cells Hypersensitive to PARP Inhibition
2020
Author(s) : Leong Sze Wei Source : ACS Chemical Biology |
18. |
Synthesis and in-vitro anti-cancer evaluations of multi-methoxylated asymmetrical diarylpentanoids as intrinsic apoptosis inducer against colorectal cancer
2020
Author(s) : Leong Sze Wei Source : Bioorganic and Medicinal Chemistry Letters |
19. |
Identification of α-glucosidase inhibitory compounds from Curcuma mangga fractions.
2020
Author(s) : Leong Sze Wei Source : International Journal of Food Properties |
20. |
Synthesis and biological evaluation of asymmetrical diarylpentanoids as antiinflammatory, anti-α-glucosidase, and antioxidant agents
2019
Author(s) : Leong Sze Wei Source : Medicinal Chemistry Research |
21. |
Phytochemical and bioactivity alterations of Curcuma species harvested at different growth stages by NMR-based metabolomics
2019
Author(s) : Leong Sze Wei Source : Journal of Food Composition and Analysis |
22. |
Anti-edematogenic and anti-granuloma activity of a synthetic curcuminoid analog, 5-(3,4-dihydroxyphenyl)-3-hydroxy-1-(2-hydroxyphenyl)penta-2,4-dien-1-one, in mouse models of inflammation.
2019
Author(s) : Leong Sze Wei Source : Molecules |
23. |
Chemical constituents and biological activities of south east asia marine sponges: A review
2019
Author(s) : Leong Sze Wei Source : Pertanika Journal of Science and Technology |
24. |
Effect of diarylpentanoid analogues on lipopolysaccharide-induced interleukin-6 and interleukin-8 gene expression in airway inflammation
2019
Author(s) : Leong Sze Wei Source : Malaysian Journal of Medicine and Health Sciences |
25. |
Induction of cell cycle arrest and apoptosis by copper complex Cu(SBCM)2 towards oestrogen-receptor positive MCF-7 breast cancer cells.
2019
Author(s) : Leong Sze Wei Source : RSC Advances |
26. |
Novel 2-Benzoyl-6-(2,3-Dimethoxybenzylidene)-Cyclohexenol Confers Selectivity toward Human MLH1 Defective Cancer Cells through Synthetic Lethality
2019
Author(s) : Leong Sze Wei Source : SLAS Discovery |
27. |
Analgesic effect of 5-(3,4-Dihydroxyphenyl)-3-hydroxy-1-(2-hydroxyphenyl)penta-2,4-dien-1-one in experimental animal models of nociception.
2018
Author(s) : Leong Sze Wei Source : Molecules |
28. |
Asymmetrical meta-methoxylated diarylpentanoids: Rational design, synthesis and anti-cancer evaluation in-vitro.
2018
Author(s) : Leong Sze Wei Source : European Journal of Medicinal Chemistry |
29. |
In vitro and in silico evaluations of diarylpentanoid series as α-glucosidase inhibitor
2018
Author(s) : Leong Sze Wei Source : Bioorganic and Medicinal Chemistry Letters |
30. |
Optimization of enzymatic esterification of dihydrocaffeic acid with hexanol in ionic liquid using response surface methodology.
2017
Author(s) : Leong Sze Wei Source : Chemistry Central Journal |
31. |
Alpha-Glucosidase Inhibitory and Antioxidant Activities of Different Ipomoea aquatica Cultivars and LC MS/MS Profiling of the Active Cultivar
2017
Author(s) : Leong Sze Wei Source : Journal of Food Biochemistry. |
32. |
Zebrafish phenotypic screen identifies novel Notch antagonists
2017
Author(s) : Leong Sze Wei Source : Investigational New Drugs |
33. |
Effect of different drying methods and solvent ratios on biological activities of Phyllanthus acidus extracts
2017
Author(s) : Leong Sze Wei Source : International Food Research Journal |
34. |
Comparative study of the antioxidant activities of some lipase-catalyzed alkyl dihydrocaffeates synthesized in ionic liquid
2017
Author(s) : Leong Sze Wei Source : Food Chemistry |
35. |
Suppression of PGE2 production via disruption of MAPK phosphorylation by unsymmetrical dicarbonyl curcumin derivatives
2017
Source : Medicinal Chemistry Research DOI : 10.1007/s00044-017-2025-4 |
36. |
Chemical constituents and biological activities of Callicarpa maingayi leaves
2016
Author(s) : Leong Sze Wei Source : South African Journal of Botany |
37. |
2-Benzoyl-6-benzylidenecyclohexanone analogs as potent dual inhibitors of acetylcholinesterase and butyrylcholinesterase
2016
Author(s) : Leong Sze Wei Source : Bioorganic and Medicinal Chemistry |
38. |
Design and synthesis of a novel mPGES-1 lead inhibitor guided by 3D-QSAR CoMFA
2016
Author(s) : Leong Sze Wei Source : RSC Advances |
39. |
Synthesis of unsymmetrical monocarbonyl curcumin analogues with potent inhibition on prostaglandin E2 production in LPS-induced murine and human macrophages cell lines
2016
Author(s) : Leong Sze Wei Source : Bioorganic and Medicinal Chemistry Letters |
40. |
Synthesis and effects of oxadiazole derivatives on tyrosinase activity and human SK-MEL-28 malignant melanoma cells
2016
Author(s) : Leong Sze Wei Source : RSC Advances |
41. |
Nitric oxide inhibitory activity and antioxidant evaluations of 2-benzoyl-6-benzylidenecyclohexanone analogs, a novel series of curcuminoid and diarylpentanoid derivatives
2015
Author(s) : Leong Sze Wei Source : Bioorganic and Medicinal Chemistry Letters |
42. |
Synthesis, biological evaluation and QSAR studies of diarylpentanoid analogues as potential nitric oxide inhibitors
2015
Author(s) : Leong Sze Wei Source : MedChemComm |
43. |
Phytochemical diversity of Clinacanthus nutans extracts and their bioactivity correlations elucidated by NMR based metabolomics
2015
Author(s) : Leong Sze Wei Source : Phytochemistry Letters |
44. |
Synthesis, bioactivity evaluation, and docking study of 5-aminosalicylic acid’s fatty acid derivatives
2015
Author(s) : Leong Sze Wei Source : Monatshefte Fur Chemie |
45. |
Differentiation of Nigella sativa seeds from four different origins and their bioactivity correlations based on NMR-metabolomics approach
2015
Author(s) : Leong Sze Wei Source : Phytochemistry Letters |
46. |
Inhibition of prostaglandin E2 production by synthetic minor prenylated chalcones and flavonoids: Synthesis, biological activity, crystal structure, and in silico evaluation
2014
Author(s) : Kamal Rullah,Leong Sze Wei Source : Bioorganic & Medicinal Chemistry Letters DOI : 10.1016/j.bmcl.2014.06.061 |
47. |
Synthesis and sar study of diarylpentanoid analogues as new anti-inflammatory agents
2014
Author(s) : Leong Sze Wei Source : Molecules |
BOOK
NO | DETAILS OF BOOK |
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PROCEEDING
NO | DETAILS OF PROCEEDING |
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RESEARCH PROJECT
GRANT | PROGRESS | STATUS |
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Design, Synthesis And Anti-cancer Evaluation Of Phenylpyrazole-styryl Hybrids As Multi Target Agents Against Egfr And Vegfrs
Researcher(s) : Prof. Dr. Cheng Sit Foon,Dr. Abdullah Al-hadi Bin Ahmad Fuaad,Associate Prof. Dr. Lim Yat Yuen
(Bantuan Khas Penyelidikan (BKP Special)) |
|
new |
Structural Optimization of AP21 as EGFR-Targeting Anti-Cancer Agents
Researcher(s) : Associate Prof. Dr. Lim Yat Yuen
(UM International Collaboration Grant) |
|
on going |
RESEARCH COLLABORATOR
GRANT | PROGRESS | STATUS |
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WP2: Development of Novel Therapeutic Agent and Delivery Method for Lung Cancer
(Others MOHE - Top 100 (IIRG)-FNW) |
|
on going |