ARTICLE IN ACADEMIC JOURNALS
| NO | DETAILS OF ARTICLE IN ACADEMIC JOURNALS |
|---|---|
| 1. |
Immunomodulatory Effect and an Intervention of TNF Signalling Leading to Apoptotic and Cell Cycle Arrest on ORL-204 Oral Cancer Cells by Tiger Milk Mushroom, Lignosus rhinocerus
2022
Source : FOOD TECHNOLOGY AND BIOTECHNOLOGY DOI : 10.17113/ftb.60.01.22.7296 |
| 2. |
A novel orally infected hamster model for Coxsackievirus A16 hand-foot-and-mouth disease and encephalomyelitis.
2020
Author(s) : Ong Kien Chai Source : Laboratory Investigation |
| 3. |
Japanese encephalitis virus: Biological clones from a clinical isolate quasispecies show differing neurovirulence in vitro and in a mouse model.
2020
Author(s) : Ong Kien Chai Source : Neurology Asia |
| 4. |
Myricetin derivative-rich fraction from Syzygium malaccense prevents high-fat diet-induced obesity, glucose intolerance and oxidative stress in C57BL/6J mice.
2020
Author(s) : Umah Rani A/p Kuppusamy,Ong Kien Chai Source : ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY |
| 5. |
Coxsackievirus A16 in a 1-Day-Old Mouse Model of Central Nervous System Infection Shows Lower Neurovirulence than Enterovirus A71.
2020
Author(s) : Ong Kien Chai Source : Journal of Comparative Pathology |
| 6. |
Electrostatic interactions at the five-fold axis alter heparin-binding phenotype and drive enterovirus A71 virulence in mice.
2019
Author(s) : Ong Kien Chai Source : PLoS Pathogen |
| 7. |
Development of live attenuated Enterovirus 71 vaccine strains that confer protection against lethal challenge in mice.
2019
Author(s) : Ong Kien Chai Source : Scientific Reports |
| 8. |
Neuronal transcriptomic responses to Japanese encephalitis virus infection with a special focus on chemokine CXCL11 and pattern recognition receptors RIG-1 and MDA5.
2019
Author(s) : Wong Kum Thong,Ong Kien Chai Source : Virology |
| 9. |
Polymorphisms in the androgen receptor CAG repeat sequence are related to tumour stage but not to ERG or androgen receptor expression in Malaysian men with prostate cancer.
2019
Source : Malaysian Journal of Pathology |
| 10. |
RSAD2 and AIM2 Modulate Coxsackievirus A16 and Enterovirus A71 Replication in Neuronal Cells in Different Ways That May Be Associated with Their 5' Nontranslated Regions.
2018
Author(s) : Ong Kien Chai Source : Journal of Virology |
| 11. |
Identification and characterization of neutralization epitopes at VP2 and VP1 of enterovirus A71
2018
Author(s) : Ong Kien Chai,Jamal I-ching Sam Source : JOURNAL OF MEDICAL VIROLOGY DOI : 10.1002/jmv.25061 |
| 12. |
Heterogenous expression of ERG oncoprotein in Malaysian men with adenocarcinoma of the prostate
2018
Source : Malaysian Journal of Pathology |
| 13. |
The gastric microbiome of four Malaysian gastroduodenal diseases patients
2017
Author(s) : Ong Kien Chai Source : Gene and Genome Research |
| 14. |
Modelling person-to-person transmission in an Enterovirus A71 orally infected hamster model of hand-foot-and-mouth disease and encephalomyelitis
2017
Author(s) : Wong Kum Thong,Ong Kien Chai Source : Emerging Microbes & Infections |
| 15. |
Mechanisms of action and in vivo antibacterial efficacy assessment of five novel hybrid peptides derived from Indilicidin and Ranalexin against Streptococcus pneumoniae
2017
Author(s) : Ong Kien Chai Source : PeerJ DOI : 10.7717/peerj.3887 |
| 16. |
Enterovirus A71 and Coxsackievirus A16 show different replication kinetics in human neuronal and non-neuronal cell lines.
2017
Author(s) : Wong Kum Thong,Ong Kien Chai Source : Archives Virology |
| 17. |
AIM2 inflammasome-mediated pyrotosis in Enterovirus A71 infected neuronal cells restricts viral replication
2017
Author(s) : Wong Kum Thong,Ong Kien Chai Source : Scientific Reports |
| 18. |
The role of heat shock proteins and glucose regulated proteins in cancer.
2016
Author(s) : Ong Kien Chai,Charles Anthony Rhodes Source : Malaysia J Pathology |
| 19. |
A monoclonal antibody to ameliorate central nervous system infection and improve survival in a murine model of human Enterovirus-A71 encephalomyelitis.
2016
Source : Antiviral Research |
| 20. |
A consistently orally-infected hamster model for Enterovirus A71 encephalomyelitis demonstrates squamous lesions in the paws, skin and oral cavity reminiscent of Hand-Foot-and-Mouth Disease
2016
Author(s) : Wong Kum Thong,Ong Kien Chai Source : PLOS ONE DOI : 10.1371/journal.pone.0147463 |
| 21. |
Viral neuronotropism is important in the pathogenesis of Murray Valley encephalitis.
2016
Author(s) : Wong Kum Thong,Ong Kien Chai Source : Neuropathology and Applied Neurobiology |
| 22. |
Case report: Incidental splenic granuloma due to Burkholderia pseudomallei: A case of asymatic latent meliodosis?
2016
Author(s) : Wong Kum Thong,Ong Kien Chai Source : Am. J. Trop. Hyg |
| 23. |
Neurovirulence comparison of chikungunya virus isolates of the Asia and East/Central/South African genotypes from Malaysia.
2015
Author(s) : Wong Kum Thong,Ong Kien Chai Source : Journal of General Virology |
| 24. |
Validation and utilization of an internally controlled multiplex real-time RT-PCR assay for simultaneous detection of enteroviruses and enterovirus 71 associated hand foot and mouth disease
2015
Author(s) : Wong Kum Thong,Ong Kien Chai Source : Virology Journal |
| 25. |
Pathological findings in a mouse model for Coxsackievirus A16 infection.
2015
Author(s) : Wong Kum Thong,Ong Kien Chai Source : NEUROLOGY ASIA |
| 26. |
A generic assay for whole-genome amplification and deep sequencing of enterovirus A71
2015
Author(s) : Wong Kum Thong,Ong Kien Chai Source : Journal of Virological Methods |
| 27. |
Henipavirus encephalitis: Recent developments and advances
2015
Author(s) : Wong Kum Thong,Ong Kien Chai Source : Brain Pathology |
| 28. |
Understanding Enterovirus 71 neuropathogensis and its impact on other neurotropic enteroviruses
2015
Author(s) : Wong Kum Thong,Ong Kien Chai Source : Brain Pathology |
| 29. |
Immunity and clinical efficacy of an inactivated enterovirus 71 vaccine in healthy Chinese children: a report of further observations.
2015
Author(s) : Wong Kum Thong,Ong Kien Chai Source : BMC Medicine |
| 30. |
Pathological findings in a mouse model of Japanese encephalitis infected via the foot pad
2015
Author(s) : Wong Kum Thong,Ong Kien Chai Source : NEUROLOGY ASIA |
| 31. |
Tonsillar crypt epithelium is an important extracentral nervous system site for viral replication in EV71 encephalomyelitis
2014
Author(s) : Wong Kum Thong,Ong Kien Chai Source : American Journal of Pathology |
| 32. |
In situ hybridization to detect and identify Burkholderia pseudomallei in human melioidosis
2014
Source : Modern Pathology |
| 33. |
Enterovirus 71 can directly infected the brainstem via cranial nerves and infection can be ameliorated by passive immunization
2014
Source : Journal of Neuropathology and Experimental Neurology |
| 34. |
Effects of cocktail of four local Malaysian Medicinal plants (Phyllanthus spp.) against dengue virus 2
2013
Author(s) : Ong Kien Chai |
| 35. |
Transgenic mouse model for the study of enterovirus 71 neuropathogenesis
2013
Author(s) : Ong Kien Chai |
| 36. |
Aberrant proteins in the saliva of patients with oral squamous cell carcinoma.
2013
Author(s) : Onn Bin Haji Hashim,Wong Kum Thong,Rosnah Binti Mohd Zain,Zubaidah @ Jubaidah Binti Haji Abd. Rahim,Ong Kien Chai Source : Electrophoresis |
| 37. |
Protection against Henipavirus infection by use of
recombinant adeno-associated virus-vector vaccines.
2013
Author(s) : Ong Kien Chai |
| 38. |
Immunization with recombinant
enterovirus 71 viral capsid protein 1 fragment
stimulated antibody responses in hamsters.
2012
Author(s) : Ong Kien Chai Source : Virology Journal |
| 39. |
Lethal Nipah Virus infection induces rapid
overexpression of CXCL10
2012
Author(s) : Ong Kien Chai Source : Plos One |
| 40. |
Enterovirus 71 encephalomyelitis and Japanese
encephalitis can be distinguished by topographic
distribution of inflammation and specific
intraneuronal
detection of viral antigen and RNA
2012
Author(s) : Ong Kien Chai |
| 41. |
Pathology of acute henipavirus infection in humans
and
animals
2011
Author(s) : Ong Kien Chai |
| 42. |
Partial Protection Against Enterovirus 71 (EV71)
Infection in a Mouse Model Immunized With
Recombinant Newcastle Disease Virus Capsids
Displaying the EV71 VP1 Fragment
2011
Author(s) : Ong Kien Chai Source : JOURNAL OF MEDICAL VIROLOGY |
| 43. |
Formaldehyde-inactivated whole-virus vaccine
protects a murine model of enterovirus 71
encephalomyelitis.
against disease
2010
Author(s) : Ong Kien Chai Source : J.Virol |
BOOK
| NO | DETAILS OF BOOK |
|---|---|
| 1. |
Future direction of Biomedical Science Programme in
Malaysia, 2011.
2011
Author(s) : Ong Kien Chai |
CHAPTER IN BOOK
| NO | DETAILS OF CHAPTER IN BOOK |
|---|
PROCEEDING
| NO | DETAILS OF PROCEEDING |
|---|---|
| 1. |
Enterovirus 71 infection in the mouse and hamster as
models for viral myositis studies
2010
Author(s) : Ong Kien Chai |
| 2. |
Formaldehyde-inactivated whole virus vaccine protects a
murine model of Enterovirus 71 Encephalomyelitis
against infection.
2009
Author(s) : Ong Kien Chai |
RESEARCH PROJECT
| GRANT | PROGRESS | STATUS |
|---|---|---|
|
The Role Of Glucose Regulated Proteins And Related Biomarkers In Breast And Prostate Cancer
Researcher(s) : -
(Postgraduate Research Grant (PPP) - Research) |
|
end |
|
Neuronal Injury In Japanese Encephalitis Virus Infection
Researcher(s) : -
(Postgraduate Research Grant (PPP) - Research) |
|
end |
|
Evaluation Of Invitro And Invivo Immune Responses In Murine Model Of Human Enterovirus 71 Encephalomyelitis
Researcher(s) : Associate Prof. Dr. Ong Kien Chai
(Fundamental Research Grant Scheme (FRGS)) |
|
end |
|
Studies Of Enterovirus A71 And Coxsackievirus A16 Epidermotropism And Infection Of Squamous Cells In Human Skin And Palatine Tonsil Organotypic Culture System.
Researcher(s) : Dr. Shalini A/p Vellasamy
(Fundamental Research Grant Scheme (FRGS)) |
|
end |
|
Activation Of The Androgen Receptor In Malaysia Men With Prostate Cancer
(Bantuan Khas Penyelidikan (BKP Special)) |
|
end |
|
Enterovirus 71 Infection: Studies Of Viral Transmission In The Nervous System In Mouse Model.
Researcher(s) : Prof. Dr. Wong Kum Thong
(Geran Penyelidikan Universiti Malaya (UMRG) - HTM (Wellness)) |
|
end |
RESEARCH COLLABORATOR
| GRANT | PROGRESS | STATUS |
|---|---|---|
|
Characterizing The Epidemiological Diversity Of Nipah Strains
Researcher(s) : Emeritus Prof. Dr. Tan Chong Tin,Prof. Dr. Wong Kum Thong,Prof. Dr. Wong Li Ping,Associate Prof. Dr. Tee Kok Keng,Associate Prof. Dr. Ong Kien Chai,Dr. Nuryana Binti Idris,Dr. Tan Soon Hao,Dr. Schee Jie Ping
(International Funding) |
|
new |
|
Mushroom Based-food For Metabolic Syndrome: Safety Assessment And Validation Through A Pilot Study
Researcher(s) : Associate Prof. Dr. Ong Kien Chai,Prof. Dr. Noran Naqiah Binti Mohd Hairi,Awang Bulgiba Awang Mahmud,Dr. Bavani A/p Arumugam
(Others MOHE - Top 100 (IIRG)-HWB) |
|
on going |
|
Japanese Encephalitis: Viral Genomic Neurovirulence Determinants And The Role Of Peripheral Sensory Nerves In Neuroinvasion
Researcher(s) : Associate Prof. Dr. Ong Kien Chai,Prof. Dr. Wong Kum Thong
(RU Geran) |
|
end |
|
Characterization And Evaluation Of Tfbg Biosensor To Detect Enteroviruses Associated With Hand-foot-and Mouth Disease
Researcher(s) : Associate Prof. Dr. Ong Kien Chai,Prof. Dr. Wong Kum Thong
(Others MOHE - Top 100 (IIRG)-HWB) |
|
end |
|
Development Of A Proof-of-concept Viral Vaccine With Codon And Codon-pair Deoptimization : Enterovirus A71 Attenuated Vaccine
Researcher(s) : Dr. Tan Chee Wah,Prof. Dr. Wong Kum Thong,Associate Prof. Dr. Ong Kien Chai,Prof. Dr. Jamal I-ching Sam
(MOSTI-Science Fund) |
|
end |
|
Tropism Of Zika Virus, In Vitro And In Vivo And Its Ability To Cross Various Human Vascular Endothelium Beds
Researcher(s) : Prof. Dr. Shamala Devi A/p K.c Sekaran,Associate Prof. Dr. Ong Kien Chai,Dr. Yong Yean Kong,Mohammad Asif Khan
(Fundamental Research Grant Scheme (FRGS)) |
|
end |
|
Screening of several potential local natural products as prophylaxis against Hand Foot and Mouth Disease.
Researcher(s) : Associate Prof. Dr. Ong Kien Chai,Prof. Dr. Wong Kum Thong
(Bantuan Kecil Penyelidikan (BKP)) |
|
end |
|
Evaluation Of Invitro And Invivo Immune Responses In Murine Model Of Human Enterovirus 71 Encephalomyelitis
Researcher(s) : Associate Prof. Dr. Ong Kien Chai
(Fundamental Research Grant Scheme (FRGS)) |
|
end |
|
ANTI-VIRAL EFFECTS OF IN-HOUSE MALAYSIAN PLANT EXTRACTS COLLECTION TOWARDS JAPANESE ENCEPHALITIS VIRUS (JEV) INFECTION IN NEURONAL CELLS
Researcher(s) : Prof. Dr. Mohd Rais Bin Mustafa,Prof. Dr. Wong Kum Thong,Associate Prof. Dr. Wong Won Fen,Associate Prof. Dr. Ong Kien Chai
(Geran Penyelidikan Universiti Malaya (UMRG) - HTM (Wellness)) |
|
end |