ARTICLE IN ACADEMIC JOURNALS
| NO | DETAILS OF ARTICLE IN ACADEMIC JOURNALS |
|---|---|
| 1. |
Immunomodulatory Effect and an Intervention of TNF Signalling Leading to Apoptotic and Cell Cycle Arrest on ORL-204 Oral Cancer Cells by Tiger Milk Mushroom, Lignosus rhinocerus
2022
Source :
FOOD TECHNOLOGY AND BIOTECHNOLOGY
DOI :
10.17113/ftb.60.01.22.7296
|
| 2. |
Japanese encephalitis virus: Biological clones from a clinical isolate quasispecies show differing neurovirulence in vitro and in a mouse model.
2020
Author(s) : Ong Kien Chai Source :
Neurology Asia
|
| 3. |
A novel orally infected hamster model for Coxsackievirus A16 hand-foot-and-mouth disease and encephalomyelitis.
2020
Author(s) : Ong Kien Chai Source :
Laboratory Investigation
|
| 4. |
Myricetin derivative-rich fraction from Syzygium malaccense prevents high-fat diet-induced obesity, glucose intolerance and oxidative stress in C57BL/6J mice.
2020
Author(s) : Umah Rani A/p Kuppusamy, Ong Kien Chai Source :
ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY
|
| 5. |
Coxsackievirus A16 in a 1-Day-Old Mouse Model of Central Nervous System Infection Shows Lower Neurovirulence than Enterovirus A71.
2020
Author(s) : Ong Kien Chai Source :
Journal of Comparative Pathology
|
| 6. |
Electrostatic interactions at the five-fold axis alter heparin-binding phenotype and drive enterovirus A71 virulence in mice.
2019
Author(s) : Ong Kien Chai Source :
PLoS Pathogen
|
| 7. |
Development of live attenuated Enterovirus 71 vaccine strains that confer protection against lethal challenge in mice.
2019
Author(s) : Ong Kien Chai Source :
Scientific Reports
|
| 8. |
Neuronal transcriptomic responses to Japanese encephalitis virus infection with a special focus on chemokine CXCL11 and pattern recognition receptors RIG-1 and MDA5.
2019
Author(s) : Wong Kum Thong, Ong Kien Chai Source :
Virology
|
| 9. |
Polymorphisms in the androgen receptor CAG repeat sequence are related to tumour stage but not to ERG or androgen receptor expression in Malaysian men with prostate cancer.
2019
Source :
Malaysian Journal of Pathology
|
| 10. |
RSAD2 and AIM2 Modulate Coxsackievirus A16 and Enterovirus A71 Replication in Neuronal Cells in Different Ways That May Be Associated with Their 5' Nontranslated Regions.
2018
Author(s) : Ong Kien Chai Source :
Journal of Virology
|
| 11. |
Identification and characterization of neutralization epitopes at VP2 and VP1 of enterovirus A71
2018
Author(s) : Jamal I-ching Sam, Ong Kien Chai Source :
JOURNAL OF MEDICAL VIROLOGY
DOI :
10.1002/jmv.25061
|
| 12. |
Heterogenous expression of ERG oncoprotein in Malaysian men with adenocarcinoma of the prostate
2018
Source :
Malaysian Journal of Pathology
|
| 13. |
The gastric microbiome of four Malaysian gastroduodenal diseases patients
2017
Author(s) : Ong Kien Chai Source :
Gene and Genome Research
|
| 14. |
Modelling person-to-person transmission in an Enterovirus A71 orally infected hamster model of hand-foot-and-mouth disease and encephalomyelitis
2017
Author(s) : Wong Kum Thong, Ong Kien Chai Source :
Emerging Microbes & Infections
|
| 15. |
Mechanisms of action and in vivo antibacterial efficacy assessment of five novel hybrid peptides derived from Indilicidin and Ranalexin against Streptococcus pneumoniae
2017
Author(s) : Ong Kien Chai Source :
PeerJ
DOI :
10.7717/peerj.3887
|
| 16. |
Enterovirus A71 and Coxsackievirus A16 show different replication kinetics in human neuronal and non-neuronal cell lines.
2017
Author(s) : Wong Kum Thong, Ong Kien Chai Source :
Archives Virology
|
| 17. |
AIM2 inflammasome-mediated pyrotosis in Enterovirus A71 infected neuronal cells restricts viral replication
2017
Author(s) : Wong Kum Thong, Ong Kien Chai Source :
Scientific Reports
|
| 18. |
The role of heat shock proteins and glucose regulated proteins in cancer.
2016
Author(s) : Charles Anthony Rhodes, Ong Kien Chai Source :
Malaysia J Pathology
|
| 19. |
A monoclonal antibody to ameliorate central nervous system infection and improve survival in a murine model of human Enterovirus-A71 encephalomyelitis.
2016
Source :
Antiviral Research
|
| 20. |
A consistently orally-infected hamster model for Enterovirus A71 encephalomyelitis demonstrates squamous lesions in the paws, skin and oral cavity reminiscent of Hand-Foot-and-Mouth Disease
2016
Author(s) : Wong Kum Thong, Ong Kien Chai Source :
PLOS ONE
DOI :
10.1371/journal.pone.0147463
|
| 21. |
Viral neuronotropism is important in the pathogenesis of Murray Valley encephalitis.
2016
Author(s) : Wong Kum Thong, Ong Kien Chai Source :
Neuropathology and Applied Neurobiology
|
| 22. |
Case report: Incidental splenic granuloma due to Burkholderia pseudomallei: A case of asymatic latent meliodosis?
2016
Author(s) : Wong Kum Thong, Ong Kien Chai Source :
Am. J. Trop. Hyg
|
| 23. |
Neurovirulence comparison of chikungunya virus isolates of the Asia and East/Central/South African genotypes from Malaysia.
2015
Author(s) : Wong Kum Thong, Ong Kien Chai Source :
Journal of General Virology
|
| 24. |
Validation and utilization of an internally controlled multiplex real-time RT-PCR assay for simultaneous detection of enteroviruses and enterovirus 71 associated hand foot and mouth disease
2015
Author(s) : Wong Kum Thong, Ong Kien Chai Source :
Virology Journal
|
| 25. |
Pathological findings in a mouse model for Coxsackievirus A16 infection.
2015
Author(s) : Ong Kien Chai, Wong Kum Thong Source :
NEUROLOGY ASIA
|
| 26. |
A generic assay for whole-genome amplification and deep sequencing of enterovirus A71
2015
Author(s) : Wong Kum Thong, Ong Kien Chai Source :
Journal of Virological Methods
|
| 27. |
Henipavirus encephalitis: Recent developments and advances
2015
Author(s) : Wong Kum Thong, Ong Kien Chai Source :
Brain Pathology
|
| 28. |
Understanding Enterovirus 71 neuropathogensis and its impact on other neurotropic enteroviruses
2015
Author(s) : Ong Kien Chai, Wong Kum Thong Source :
Brain Pathology
|
| 29. |
Immunity and clinical efficacy of an inactivated enterovirus 71 vaccine in healthy Chinese children: a report of further observations.
2015
Author(s) : Wong Kum Thong, Ong Kien Chai Source :
BMC Medicine
|
| 30. |
Pathological findings in a mouse model of Japanese encephalitis infected via the foot pad
2015
Author(s) : Wong Kum Thong, Ong Kien Chai Source :
NEUROLOGY ASIA
|
| 31. |
Tonsillar crypt epithelium is an important extracentral nervous system site for viral replication in EV71 encephalomyelitis
2014
Author(s) : Wong Kum Thong, Ong Kien Chai Source :
American Journal of Pathology
|
| 32. |
In situ hybridization to detect and identify Burkholderia pseudomallei in human melioidosis
2014
Source :
Modern Pathology
|
| 33. |
Enterovirus 71 can directly infected the brainstem via cranial nerves and infection can be ameliorated by passive immunization
2014
Source :
Journal of Neuropathology and Experimental Neurology
|
| 34. |
Effects of cocktail of four local Malaysian Medicinal plants (Phyllanthus spp.) against dengue virus 2
2013
Author(s) : Ong Kien Chai |
| 35. |
Transgenic mouse model for the study of enterovirus 71 neuropathogenesis
2013
Author(s) : Ong Kien Chai |
| 36. |
Aberrant proteins in the saliva of patients with oral squamous cell carcinoma.
2013
Author(s) : Zubaidah @ Jubaidah Binti Haji Abd. Rahim, Rosnah Binti Mohd Zain, Wong Kum Thong, Ong Kien Chai, Onn Bin Haji Hashim Source :
Electrophoresis
|
| 37. |
Protection against Henipavirus infection by use of
recombinant adeno-associated virus-vector vaccines.
2013
Author(s) : Ong Kien Chai |
| 38. |
Immunization with recombinant
enterovirus 71 viral capsid protein 1 fragment
stimulated antibody responses in hamsters.
2012
Author(s) : Ong Kien Chai Source :
Virology Journal
|
| 39. |
Lethal Nipah Virus infection induces rapid
overexpression of CXCL10
2012
Author(s) : Ong Kien Chai Source :
Plos One
|
| 40. |
Enterovirus 71 encephalomyelitis and Japanese
encephalitis can be distinguished by topographic
distribution of inflammation and specific
intraneuronal
detection of viral antigen and RNA
2012
Author(s) : Ong Kien Chai |
| 41. |
Pathology of acute henipavirus infection in humans
and
animals
2011
Author(s) : Ong Kien Chai |
| 42. |
Partial Protection Against Enterovirus 71 (EV71)
Infection in a Mouse Model Immunized With
Recombinant Newcastle Disease Virus Capsids
Displaying the EV71 VP1 Fragment
2011
Author(s) : Ong Kien Chai Source :
JOURNAL OF MEDICAL VIROLOGY
|
| 43. |
Formaldehyde-inactivated whole-virus vaccine
protects a murine model of enterovirus 71
encephalomyelitis.
against disease
2010
Author(s) : Ong Kien Chai Source :
J.Virol
|
BOOK
| NO | DETAILS OF BOOK |
|---|---|
| 1. |
Future direction of Biomedical Science Programme in
Malaysia, 2011.
2011
Author(s) : Ong Kien Chai |
CHAPTER IN BOOK
| NO | DETAILS OF CHAPTER IN BOOK |
|---|
PROCEEDING
| NO | DETAILS OF PROCEEDING |
|---|---|
| 1. |
Enterovirus 71 infection in the mouse and hamster as
models for viral myositis studies
2010
Author(s) : Ong Kien Chai |
| 2. |
Formaldehyde-inactivated whole virus vaccine protects a
murine model of Enterovirus 71 Encephalomyelitis
against infection.
2009
Author(s) : Ong Kien Chai |
RESEARCH PROJECT
| GRANT | PROGRESS | STATUS |
|---|---|---|
|
The Role Of Glucose Regulated Proteins And Related Biomarkers In Breast And Prostate Cancer
Researcher(s) : - |
|
on going |
|
Neuronal Injury In Japanese Encephalitis Virus Infection
Researcher(s) : - |
|
end |
|
Evaluation Of Invitro And Invivo Immune Responses In Murine Model Of Human Enterovirus 71 Encephalomyelitis
Researcher(s) : Associate Prof. Dr. Ong Kien Chai |
|
end |
|
Studies Of Enterovirus A71 And Coxsackievirus A16 Epidermotropism And Infection Of Squamous Cells In Human Skin And Palatine Tonsil Organotypic Culture System.
Researcher(s) : Dr. Shalini A/p Vellasamy |
|
end |
|
Activation Of The Androgen Receptor In Malaysia Men With Prostate Cancer
|
|
end |
|
Enterovirus 71 Infection: Studies Of Viral Transmission In The Nervous System In Mouse Model.
Researcher(s) : Prof. Dr. Wong Kum Thong |
|
end |
RESEARCH COLLABORATOR
| GRANT | PROGRESS | STATUS |
|---|---|---|
|
Development Of A Proof-of-concept Viral Vaccine With Codon And Codon-pair Deoptimization : Enterovirus A71 Attenuated Vaccine
|
|
end |
|
Tropism Of Zika Virus, In Vitro And In Vivo And Its Ability To Cross Various Human Vascular Endothelium Beds
Researcher(s) : Prof. Dr. Shamala Devi A/p K.c Sekaran, Associate Prof. Dr. Ong Kien Chai, Dr. Yong Yean Kong, Mohammad Asif Khan |
|
end |
|
Screening of several potential local natural products as prophylaxis against Hand Foot and Mouth Disease.
Researcher(s) : Associate Prof. Dr. Ong Kien Chai, Prof. Dr. Wong Kum Thong |
|
end |
|
Evaluation Of Invitro And Invivo Immune Responses In Murine Model Of Human Enterovirus 71 Encephalomyelitis
Researcher(s) : Associate Prof. Dr. Ong Kien Chai |
|
end |
|
ANTI-VIRAL EFFECTS OF IN-HOUSE MALAYSIAN PLANT EXTRACTS COLLECTION TOWARDS JAPANESE ENCEPHALITIS VIRUS (JEV) INFECTION IN NEURONAL CELLS
|
|
end |