PERSONAL DETAIL


DR. ZARIDATUL AINI BINTI IBRAHIM

Department of Pharmacology
Faculty of Medicine
 
  03-79675727
  -
  zaridatulaini@um.edu.my
 Department of Pharmacology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, W.Persekutuan Kuala Lumpur, Malaysia
 
ResearcherID Link
  http://www.researcherid.com/rid/N-2626-2017

BIOGRAPHY


Dr Zaridatul Aini completed her Bachelor degree at The University of Melbourne in 2009 (Bachelor of Science majoring in Pharmacology and Biotechnology). She then pursued her postgraduate studies at The University of Sydney in 2011 and  completed her doctorate studies (PhD in Medicine) in early 2017. Her research expertise is focussed on understanding the cellular and molecular mechanisms underlying airway immune and inflammatory responses in asthma. Her thesis title is the “Expression and Function of Interleukin 1-alpha and High Mobility Group Box-1 in Human Airway Epithelial Cells”. During her PhD, she has mastered various research skills including cell culture (monolayer and air-liquid interface culture of human primary airway epithelial cell and human airway epithelial cell lines), human lung dissection (isolation of airway epithelial/ smooth muscle cells from the human airways), western blots, ELISA, immunofluorescence and high content microscopy techniques.

Dr Zaridatul Aini has recently joined the Pharmacology Department at the Universiti Malaya and has held a position as a senior lecturer. She has been involved in teaching or Bachelor degree courses for Pharmacy, Dentistry, Nursing and Biomedical Science. She is also a coordinator of Biomedical Science at the department. 

Dr Zaridatul Aini continues to pursue her research interests in Interleukin 1-alpha and High Mobility Group Box-1 which are among the critical damage-associated molecular pattern molecules important in the pathogenesis of various diseases. She welcomes research degree enquiries via email.  


ACADEMIC QUALIFICATION
(Qualification), (Institution).



PROFESSIONAL
(Organisation), (Role), (Year), (Level).


  • THE AUSTRALIAN SOCIETY FOR MEDICAL RESEARCH, Registered Member, 2013, (National)
  • EUROPEAN RESPIRATORY SOCIETY, Member, 2014 to 2015, (International)
  • Malaysian Society of Pharmacology and Physiology, Active Member, 2018 to 2019, (National)

ADMINISTRATIVE DUTIES
(Role), (Level), (Start date),(End Date).


  • Penasihat Akademik bagi Pelajar Peringkat 1, Kursus MBBS, Sesi Akademik 2018/2019, Faculty, 10/09/2018 to 10/09/2019 (Penasihat Akademik bagi Pelajar Peringkat 1, Kursus MBBS, Sesi Akademik 2018/2019)
  • Koordinator bagi program sains bioperubatan, jabatan farmakologi, fakulti perubatan, Faculty, 13/10/2017 to 24/07/2019 (tarikh perlantikan bermula dari tarikh surat rasmi diterima sehingga diberitahu kelak. )

AREAS OF EXPERTISE
(Area).


  • Molecular Pharmacology (inflammation, oncology, cancer)


RECENT SELECTED PUBLICATIONS
(Publication).


Article in Academic Journals

2019
  • Sanaz Koosha, Zahurin Mohamed, Ajantha Sinniah, Zaridatul Aini Ibrahim, Atefehalsadat Seyedan, Mohammed A. Alshawsh. (2019). Antiproliferative and apoptotic activities of 8-prenylnaringenin against human colon cancer cells. Life Sciences, 232 [Epub ahead printing]. (ISI-Indexed)

2016
  • Gold, M., Hiebert, P., Park, H., Stefanowicz, D., Le, A., Starkey, M., Deane, A., Brown, A., Liu, G., Horvat, J., Ibrahim, Z A., Sukkar, M., Hansbro, P., Carlsten, C., Eeden, S., Sin, D., McNagny, K., Knight, D., Hirota, J. (2015). Mucosal production of uric acid by airway epithelial cells contributes to particulate matter-induced allergic sensitization. Mucosal Immunology, 9(3), (ISI-Indexed)

2015
  • Donovan, C., Royce, S., Esposito, J., Tran, J., brahim ZA., Tang, M., Bailey, S., Bourke J. (2015) Rosiglitazone elicits in vitro relaxation in airways and precision cut lung slices from a mouse model of chronic allergic airways disease. JP Lung Cellular and Molecular Physiology 309(10). (ISI-Indexed)

2013
  • ISI-Journal article (ISI-Indexed)
  • (2013). Differential Effects of Allergen Challenge on Large and Small Airway Reactivity in Mice. PLoS ONE 8(9):e74101 (ISI-Indexed)
  • Ibrahim, Z. A., Armour, C. L., Phipps, S., Sukkar, M. B. 2013. RAGE and TLRs: Relatives, friends or neighbours?. Molecular Immunology (ISI-Indexed)
Proceeding

2015
  • Wong, S., Ibrahim Z A., Wark, P., Sukkar, M., Potential role of SPARC, a downstream mediator of TGF-b in chronic airways disease (2015). European Respiratory Journal 46(suppl 59):PA904. (ISI-Indexed)

2014
  • HMGB1 expression and function in the allergic airway immune response (ISI-Indexed)

2010
  • Bronchodilator Actions Of Rosiglitazone Are Maintained In Inflamed Airways: Potential Role Of Rho-kinase Inhibition (ISI-Indexed)

AREAS OF RESEARCH
(Project title), (Role), (From)-(Until), (Level), (Source).


  • The Relationship between ER Stress Response and Inflammasome Activation in IL-1 -Induced Colorectal Cancer Metastasis, Principal Investigator(PI), 2019 - 2021, RU Geran - Fakulti Program, (National)
  • Association of High Mobility Group Box-1 (HMGB1) and Soluble Receptor for Advanced Glycation End Products (sRAGE) Plasma Levels in Acute Myeloid Leukemia (AML) Patients, Consultant, 2018 - 2019, Private Funding, (National)
  • Investigation Of Hmgb1 And Il-1a Secretion And Function In Inflammatory Responses Of Human Colon Epithelial (normal) And Colorectal Cancer Cells., Principal Investigator(PI), 2018 - 2020, Bantuan Kecil Penyelidikan (BKP), (National)

AWARDS AND RECOGNITIONS
(Name of Award), (Awarding Institution), (Year Awarded), (Level).


  • 5 Most Highly Cited Papers Published in Molecular Immunology from 2014 – June 2016, Elsevier Publisher, 2016, (Private)
  • Wos Incentive from The Universiti of Malaya. , Universiti Malaya, 2014, (University)

EXPERT LINKAGES
(Linkages Description), (Organisation), (Year of Involvement), (Duration), (Level).


  • Research project collaboration - Association of high mobility group box-1 (HMGB1) and soluble receptor for advanced glycation end products (sRAGE) plasma levels in acute myeloid leukemia (AML) patients, Institute for Medical Research (IMR), 2018, 12, (National)

EVALUATION ACTIVITIES
(Description), (Evaluation Activity),(Year).


  • Reviewing manuscript for Asia Pacific Journal of Molecular Biology and Biotechnology ISSN 0128-7451, Article In Journal ,  (2019 - 2019)
  • Master Candidature Defence Ariwibawa Kasmani Mohd Hashim (MGN170014), Article In Journal ,  (2019 - 2019)
  • Reviewer for BMC Complementary and Alternative Medicine journal, Article In Journal ,  (2018 - 2018)
  • Penilai sesi Candidature Defence bagi calon ijazah Doktor Falsafah (PhD) - Angeline Oh Mei Feng, Penilai Sesi Candidature Defence ,  (2018 - 2018)
  • PhD Candidature Defence By Kwong Sok Chee (MHA130067) Supervisors: Associate Professor Ivy Chung (Dept. of Pharmacology, Faculty of Medicine, UM) Prof. Dr. Nur Aishah Mohd Taib (Dept. of Surgery, Faculty of Medicine, UM) Title: The role of FABP7 in triple negative breast cancer on 28th Nov 2018 (Wednesday), 12.00 pm in the Pharmacology Department Lecture Hall Faculty of Medicine, Phd Candidature Defence ,  (2018 - 2018)
  • Penemuduga program Sarjana Muda Perubatan dan Sarjana Muda Pembedahan - MMI interview, Interviewer ,  (2018 - 2018)
  • Mewakili ketua jabatan sebagai chair person/panel bagi PhD Candidature Defence By Wong Kin Ying (MHA160024), Chair Person/panel For Candidature Defence ,  (2018 - 2018)
  • PhD Candidature Defence By Intan Sofia Omar (MHA150035) Supervisors: Associate Professor Ivy Chung (Dept. of Pharmacology, Faculty of Medicine, UM) Prof. Dr. Woo Yin Ling (Dept. of Obstetric and Gynaecology, Faculty of Medicine, UM) Title: Differential effects of medroxyprogesterone acetate (MPA) in progesterone receptor signalling in benign- and cancer-associated fibroblasts of the endometrium on 28th Nov 2018 (Wednesday), 11.00 am in the Pharmacology Department Lecture Hall Faculty of Medicine, Phd Candidature Defence ,  (2018 - 2018)
  • Invigiliating for clinical exam for UMMP course - 9/4/2018, Clinical Examination ,  (2018 - 2018)
  • committee member to evaluate examiner nominations for PhD thesis Nama Calon : KONG WAI MUN (MHA120061) Bidang Penyelidikan : PHARMACOLOGY Tajuk Tesis : Pre-clinical Pharmacokinetics and Toxicological Studies of Mitragyna Speciosa Alkaloid Extract and Its Active Compound, Mitragynine, Clinical Examination ,  (2017 - 2017)
  • Mewakili ketua jabatan bagi Masters Proposal Defence By Thanusha M Ganesan Supervisors: Dr Ajantha Sinniah (Dept. of Pharmacology, Faculty of Medicine, UM) Associate Prof Dr Mohammad A. Alshawsh (Dept of Pharmacology, Faculty of Medicine, UM) Associate Prof Dr Zamri bin Chik (Dept of Pharmacology, Faculty of Medicine, UM) Title: ANNEXIN A1 REGULATES THE ANTI-CANCER EFFECTS IN COLORECTAL CANCER (CRC) CELL LINES on 21st December 2017 (Thursday), 3.00 pm in the Pharmacology Department Lecture Hall Faculty of Medicine, Wakil Ketua Jabatan ,  (2017 - 2017)

CONTRIBUTION TO SOCIETY
(Contribution To Society), (Level), (Start Date), (End Date).


  • Interviewer for Mock Interview programme for Tunas Geliga - interviewing form five students -recipients of the scholarship from Yayasan Peneraju, (Community), 16/12/2018 until 16/12/2018
  • Secretariat committee for the 33rd Scientific meeting MSPP 2019 , (National), 03/09/2018 until 16/07/2019
  • Assistant Treasurer for the steering committee of the scientific meeting of Asia Pacific Federation of Pharmacologist 2028 (APFP 2028), (Country), 04/06/2018 until 04/06/2028
  • fasilitator for program with primary school kids - Let's go to mummie's lab, (Community), 13/02/2018 until 13/02/2018
  • organizing committee for University of Malaya-University of Edinburgh Research Symposium on Metabolic Syndrome, (International), 05/12/2017 until 07/12/2017

SUPERVISION


POST GRADUATE STUDENT
(Name of Degree), (Name of Candidates), (Title of Thesis), (Academic Session)

Ongoing
  • Master Degree, Cheng Kim Jun, -, 2018/2019
  • Doctoral Degree (phd), Pushpa Gandi Sangaran, Lipopolysaccharide (LPS) preconditioning inhibits pro-inflammatory and proto-oncogenes responses and promotes cytoprotective effect in differentiated PC12 cell lines., 2018/2019
  • Doctoral Degree (phd), Pushpa Gandi Sangaran, Lipopolysaccharide (LPS) preconditioning inhibits pro-inflammatory and proto-oncogenes responses and promotes cytoprotective effect in differentiated PC12 cell lines., 2018/2019
  • Master Degree, Cheng Kim Jun, To Elucidate the Functional Roles of HMGB1 in Colorectal Cancer., 2018/2019
  • Master Degree, Cheng Kim Jun, To Elucidate the Functional Roles of HMGB1 in Colorectal Cancer., 2018/2019
  • Doctoral Degree (phd), Pushpa Gandi Sangaran, MAY PRECONDITIONING PREVENT INFLAMMATION INDUCED P53, C-MYC, HSP70 GENE OVER-EXPRESSION., 2017/2018
FIRST DEGREE/DIPLOMA/PRE-DEGREE
(Course Title), (Academic Session), (No. of Candidates)

Ongoing
  • Biomedical Science Degree Undergraduate Research Project 2018-2019 - Pomegranate juice extract induces apoptosis, cell cycle arrest and morphological changes in human colorectal cancer cell, 2018/2019, 1

TEACHING
(Course Title), (Academic Session), (No of Student), (No of Contact Hours).


FIRST DEGREE
  • GENERAL PRINCIPLES IN PHARMACOLOGY AND TOXICOLOGY, 2018/2019(1), 1, 11
  • PHARMACOTHERAPY FOR GASTROINTESTINAL AND RESPIRATORY DISORDERS, 2018/2019(1), 35, 8
  • STAGE 2 UMMP PBL 8 Endocrine, Nutrition and Sexual Health, 2018/2019(2), 8, 12
  • STAGE 1 UMMP autonomic nervous system tutorial, 2018/2019(1), 11, 2
  • PRINCIPLES IN PHARMACOLOGY AND TOXICOLOGY, 2018/2019(1), 43, 11
  • PHARMACOLOGY FOR DENTISTRY, 2018/2019(1), 52, 6
  • PHARMACOLOGY FOR DENTISTRY, 2017/2018(1), 49, 3
  • PHARMACOLOGY IN NURSING, 2017/2018(1), 24, 2
  • DRUG ACTION AND DISCOVERY, 2017/2018, 32, 3
  • UMMP STAGE 1 BLOCK 5 Respiratory Sciences, 2017/2018(1), 8, 21