PERSONAL DETAIL


ASSOCIATE PROF. DR. ZAMRI BIN CHIK

Associate Professor
Department of Pharmacology
Faculty of Medicine
 
  79676621
  +60379674791
  zamrichik@um.edu.my
 Department of Pharmacology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, W.Persekutuan Kuala Lumpur, Malaysia
 
ResearcherID Link
  http://www.researcherid.com/rid/C-1208-2010

BIOGRAPHY


Zamri obtained his BSc in Chemistry and MSc in pharmacology from the University of Malaya and later PhD in Clinical Pharmacology from the University of London (UK). He later joined the Department of pharmacology, University of Malaya as a senior lecturer and was promoted to Associate Professor in 2015. Currently he serves as head of Pharmacology Department and also Head of University of Malaya Bioequivalence Testing Centre (UBAT). His scope of research includes bioavailability and pharmacokinetic studies in human trials and also for in vivo pharmacokinetic studies using animal models. In animal models his research area further divided into conventional pharmacokinetic studies and also microdialysis which involve the measurement of drug in plasma as well as in the tissue such as brain, subcutaneous tissue, etc. His other research includes the development of transdermal and topical drug delivery system using semi solid base such as palm oil derivatives, studies on PLGA nanoparticles for the delivery of anticancer agents and bioavailability studies on other agents for anticancer. Apart from human clinical trials and preclinical studies in animals, his research also covers the screening and testing of natural product compounds derive from selected local plants. His laboratory also provides services and research in food contaminations, adulterated pharmaceutical products, xenobiotic studies on certain chemicals such as endocrine disruptors in food products, human bodies, etc. by the use of the equipments such as GCMS, HPLC, LCMSMS, etc. Apart from his research activities, he also actively provided consultation to local pharmaceutical companies to conduct testing on pharmaceutical formulations especially for bioequivalence studies, comparative dissolution, etc. His bioequivalence laboratory has conducted more than 40 bioequivalence studies for generic drug formulations and also conducting drug analysis in biological and pharmaceutical products by using state of the art chromatographic techniques such as gas chromatographic (GCMS) and liquid chromatographic mass spectrometric (LCMSMS), etc. His UBAT laboratory has two accreditations which are MS ISO 17025 for chemical testing and Ministry of Health compliance program to conduct bioequivalence studies. 

 


ACADEMIC QUALIFICATION
(Qualification), (Institution).



ADMINISTRATIVE DUTIES
(Role), (Level), (Start date),(End Date).



AREAS OF EXPERTISE
(Area).




RECENT SELECTED PUBLICATIONS
(Publication).


Article in Academic Journals

2020
  • Pushpa Gandi Sangaran, Zaridatul Aini Ibrahim, Zamri Chik, Zahurin Mohamed, Abolhassan Ahmadiani. LPS preconditioning attenuate apoptosis mechanism by inhibiting NF-κB and caspase-3 activity : TLR4 pre-activation in the signaling pathway of LPS induced neuroprotection. Molecular Neurobiology. Accepted for publication, Dec 2020 (ISI-Indexed)
  • Pushpa Gandi Sangaran, Zaridatul Aini Ibrahim, Zamri Chik, Zahurin Mohamed, Abolhassan Ahmadiani. Lipopolysaccharide preconditioning attenuates pro-inflammatory responses and promotes cytoprotective effect in differentiated PC12 cell lines via pre-activation of Toll-Like Receptor-4 signaling pathway leading to the inhibition of caspase-3/Nuclear Factor-κappa B pathway. Frontiers in Cellular Neuroscience. Accepted for publication, Dec 2020 (ISI-Indexed)
  • THANUSHA GANESAN, AJANTHA SINNIAH *, ZAMRI CHIK, MOHAMMED ABDULLAH ALSHAWSH. Punicalagin regulates apoptosis-autophagy switch via modulation of Annexin A1 in colorectal cancer. Nutrients. Nutrients 2020, 12, 2430; (ISI-Indexed)
  • Thanusha Ganesan, Ajantha Sinniah*, Zaridatul Aini Ibrahim, Zamri Chik, Mohammed Abdullah Alshawsh.Annexin A1: A bane or a boon in cancer? A Systematic review. Molecules 2020, 25, 3700 (ISI-Indexed)
  • Abubakar El-Ishaq, Mohammed A. Alshaws, Kein-Seong Mun and Zamri Chik*. Biochemical and toxicological effects of methanolic extract of Asparagus africanus Lam in Sprague-Dawley rats. Peer J. Published open access 22 June 2020 (ISI-Indexed)

2019
  • Evaluating the Oestrogenic Activities of Aqueous Root Extract of Asparagus africanus Lam in Female Sprague-Dawley Rats and Its Phytochemical Screening Using Gas Chromatography-Mass Spectrometry (GC/MS). Abubakar El-Ishaq, Mohammed Abdullah Alshawsh, Zamri Chik. Peer J (2019) .DOI 10.7717/peerj.7254 (ISI-Indexed)
  • Bioanalysis of tetrahydrobiopterin with liquid chromatographic-mass spectrometric and its application for pharmacokinetics in apolipoprotein E knockout mice. Mohd Yusmaidie Aziz & Zamri Chik. Journal of Liquid chromatography and Related Technologies. Published online: 19 Jun 2019 (ISI-Indexed)
  • Phytochemical screening and anti-implantation activity of Asparagus africanus root extract in female Sprague-Dawley rats. Abubakar El-Ishaq, Mohammed Abdullah Alshawsh, Kein-Seong Mun, Zamri Chik. Revista Brasileira De Farmacognosia. (2019). Volume 26, Page 621-630. DOI:10.1016/j.bjp.2019.06.003 (ISI-Indexed)
  • Abdulmannan H. Fateha, Zahurin Mohameda, Zamri Chika, Abdulsamad Alsalahia, Siti Rosmani Md Zainb, Mohammed A. Alshawsha. Mutagenicity and genotoxicity effects of Verbena officinalis leaves extract in Sprague-Dawley Rats. Journal of Ethnopharmacology. 235 (2019), 88-99 (ISI-Indexed)
  • R, Mac Guad et al. SAFETY AND EFFICACY OF TWO TACROLIMUS FORMULATIONS (PROGRAF® AND ADVAGRAF®) IN MALAYSIAN RENAL TRANSPLANT PATIENTS: A COMPARATIVE STUDY. Journal of Health and Translational Medicine, [S.l.], v. 22, n. 1, may 2019. (SCOPUS-Indexed)
  • Zuleen Delina Fasya Abdul Ghani,Ahmad Hazri Ab Rashid, Khozirah Shaari, Zamri Chik. Urine NMR Metabolomic Study on Biochemical Activities to Investigate the Effect of P. betle Extract on Obese Rats Applied Biochemistry and Biotechnology. https://doi.org/10.1007/s12010-019-03042-w (2019) (ISI-Indexed)
  • Abdulmannan H. Fateha, Zahurin Mohamed, Zamri Chik, Abdulsamad Alsalahia, Siti Rosmani Md Zin, Mohammed A. Alshawsh. Prenatal developmentaltoxicityevaluation ofVerbenaofficinalisduringgestation period infemaleSprague-Dawleyrats. Chemico-Biological Interactions. 304 (2019), 28-42 (ISI-Indexed)

2018
  • Effect of Catha edulis (Khat) on Pancreatic Functions in Streptozotocin-Induced Diabetes in Male Sprague-Dawley Rats (ISI-Indexed)
  • Abdullah, N. L., Gunasekaran, R., Mohd-Zin, S. W., Lim, B. H., Maniam, P., Mohd-Salleh, A. S., ... & Engkasan, J. P. (2018). Cranial neural tube defect after trimethoprim exposure. BMC research notes, 11(1), 475. (ISI-Indexed)

2017
  • Wai Mun Kong, Zamri Chik, Zahurin Mohamed and Mohammed A. Alshawsh 2017. Physicochemical Characterization of Mitragyna speciosa Alkaloid Extract and Mitragynine Using In Vitro High Throughput Assays. Combinatorial Chemistry & High Throughput Screening. 20, 1-9. DOI;10.2174/1386207320666171026121820 (ISI-Indexed)
  • Chai, H.J., Kiew, L.V., Chin, Y., Norazit, A., Mohd, Noor. S., Lo, Y.L., Looi, C.Y., Lau, Y.S., Lim, T.M., Wong, W.F., Abdullah, N.A., Abdul Sattar, M.Z., Johns, E.J., Chik, Z., Chung, L.Y. (2017) Renal Targeting Potential of a Polymeric Drug Carrier Poly-L-Glutamic Acid (PG) in Normal and Diabetic Rats. International Journal of Nanomedicine, 2017(12): 577-591, DOI: 10.2147/IJN.S111284 (IF: 4.38, Tier 1) (ISI-Indexed)
  • Hassan A. Almoustafa, Mohammed A. Alshawsh, Zamri Chik. Technical Aspects of Preparing PEG-PLGA Nanoparticles as Carrier for ‎Chemotherapeutic ‎Agents by Nanoprecipitation Method. International Journal of Pharmaceutics (2017). Volume 533, Page 275-284 (ISI-Indexed)
  • S.N. Khamdiah Khodari, Mohamed Ibrahim Noordin, Lucy Chan and Zamri Chik. In vitro and in vivo evaluation of new topical anaesthetic cream formulated with palm oil base. Current Drug Delivery (14), 690-695, 2017 (ISI-Indexed)
  • Evaluation of pharmacokinetics and Blood-Brain Barrier permeability of mitragynine using in vivo microdialysis technique. Wai Mun Kong, Zahurin Mohamed, Mohammed AL Shawsh, Zamri Chik.Journal of Pharmaceutical and Biomedical Analysis. Volume 143 (43-47), 2017 (ISI-Indexed)

2016
  • Zuleen Delina Fasya Abdul Ghani, Juani Mazmin Husin, Ahmad Hazri Ab Rashid, Khozirah Shaari, Zamri Chik (2016) Biochemical studies of Piper betle L Leaf Extract on Obese Treated Animal using 1H-NMR-Based Metabolomic Approach of Blood Serum Samples. Journal of Ethnopharmacology. Volume 194, 24 December 2016, Page 690-697 (ISI-Indexed)
  • R.M. Guad, N.L. Zaharan, Z. Chik, Z. Mohamed, B.S. Haerian, K.P. Ng, W.A.H. Wan Md Adnan. Effects of CYP3A5 Genetic Polymorphism on the Pharmacokinetics of Tacrolimus in Renal Transplant Recipients. TRANSPLANTATION PROCEEDINGS 48(1):81-87 FEBRUARY 2016. Impact Factor: 0.98 DOI: 10.1016/j.transproceed.2016.01.001 (ISI-Cited Publication) (ISI-Indexed)

2015
  • A new formulation of Gamma Delta Tocotrienol has superior bioavailability compared to an existing Tocotrienol Rich Fraction in healthy human subjects.Puvaneswari Meganathan, Rafid Salim Jabir, Ho Gwo Fuang, Nirmala Bhoo-Pathy, Roma Basu Choudhury, *Nur Aishah Taib1, Kalanithi Nesaretnam5, Zamri Chik. Article in press (Nature Scientific Report (2015) (ISI-Indexed)
  • Sritharan Nair, Zamri Chik, and Mohamed Ibrahim Noordin. In Vitro characteristics of insulin suppository developed using palm oil base (HAMIN) and its hypoglycaemic effect on rabbits. . Frontiers in Life Science Published online 10 July 2015, Volume 8, Issue 3, 2015. ISI cited publication (ISI-Indexed)
  • Didi Erwandi Mohamad Haron, Zamri Chik, Mohamed Ibrahim Noordin, Zahurin Mohamed. In Vitro and In Vivo Evaluation of A Novel Testosterone Transdermal Delivery System TTDS) Using Palm Oil Base. Iranian Journal of Basic Medical Sciences.Dec;18(12):1167-75, 2015 (ISI-Indexed)

2014
  • Shiau Hui Diong1*, Nor Shuhadah Mohd Yusoff2, Maw Shin Sim1, Raja Elina Raja Aziddin2, Zamri Chik1, Rusdi Abdul Rashid3, Norliza Chemi4, Zahurin Mohamed1 Quantitation of methadone and its metabolite in patients under maintenance treatment. Journal of Analytical Toxicology, 2014. Accepted for publication.Published Online on August 8 2014 (ISI/SCOPUS Indexed Publication)
  • Ehsan Moghaddam, Boon-Teong Teoh, Sing-Sin Sam, Rafidah Lani, Pouya Hassandarvish, Zamri Chik, Andrew Yueh, Sazaly Abubakar, and Keivan Zandi.Baicalin, a metabolite of baicalein with antiviral activity against dengue virus Scientific Report, Nature Publishing. 4:5452 (2014) (ISI-Indexed)
  • Chik , Deril N, Didi EMH, Basu RC, Ratnasingam J, and Z Mohamed . A Bioequivalence Comparison of Two Captopril Formulations (25 mg Tablets): An Open-Label, Randomized, Two-Treatment, Two-Way Crossover Study in Healthy Volunteers. Journal of Bioequivalence and Bioavailability. Journal of Bioequivalence and Bioavailability2014.Volume 6(3): 080-085 (2014) - 080 (ISI-Indexed)

2013
  • T Hairin, A.R.Marzilawati, EMH Didi , S. Mahadeva, YK Lee, N Abd Rahman, A.M.Mustafa and Z.Chik*.Quantitative LC-MS/MS Analysis of Acetaminophen Cysteine Adducts (APAP- CYS) and Its Application In Acetaminophen Overdose Patients. Analytical Methods 2013;5(8);1955-1964 (ISI-Indexed)
  • Hemmati, F. Dargahi, L. Nasoohi, S. Omidbakhsh, R. Mohamed, Z. Chik, Z. Naidu, M. & Ahmadiani, A. 2013. Neurorestorative effect of FTY720 in a rat model of Alzheimer's disease: Comparison with Memantine. Behavioural brain research, 252 : 415-421. (ISI-Indexed)

2012
  • Umar Yagoub, Awang Bulgiba, Peramalah D, Didi E, Mustafa A,Chris-topher Lee, Chik Zamri 2012. Factors affecting adherence level to HAART (Adherence predictors) in Kuala Lumpur, Malaysia. Life Science Journal 2012;9(4) 3600-3(ISI Cited Publication) (ISI-Indexed)
  • Umar Yagoub, Bulgiba AM, Didi EM, Mustafa Ali, Peramalah D, Lee C, Chik Z. Analysis of Nevirapine and Lamivudine in human plasma of HIV infected patients by high-performance liquid chromatographic-mass spectrometric (LC-MS-MS). Life Sci J 9(4)2012; 4637- 4645(ISI Cited Publication). (ISI-Indexed)

2011
  • Kong, W. M., Chik, Z., Ramachandra, M., Subramaniam, U., Aziddin, R. E. R., Mohamed, Z. 2011. Evaluation of the Effects of Mitragyna speciosa Alkaloid Extract on Cytochrome P450 Enzymes Using a High Throughput Assay Molecules. (Tier 2, Impact Factor = 1.988 ) (ISI-Indexed)
  • Chik, Z., Haron, D. E. M., Ahmad, E. D., Taha, H., Mustafa, A. M. 2011. Analysis of melamine migration from melamine food contact articles Food Additives and Contaminants Part a-Chemistry Analysis Control Exposure Risk Assessment. 287 (2011) (ISI-Indexed)
  • Umar Yagoub, Awang M Bulgiba,Didi EM, Mustafa AM, Peramalah D, Chris-topher Lee, Chik Z, 2011. Validation and analysis of Efavirenz in human plasma using high-performance liquid chromatographic-mass spectrometric (LC-MS-MS).International journal of natural product and pharmaceutical sciences Vol. 2(2), pp 72-81. (Non-ISI/Non-SCOPUS)

2010
  • Zamri Chik, Arthur T Tucker, Jukian I Shiel, David J Collier, David Perrett, Terrence D. Lee and Atholl Johnston. Comparative Pharmacokinetic Assessments of Topical Drugs: Evaluation by Dermatopharmacokinetics, Microdialysis, and Systemic Measurement. Journal of Investigative Dermatology. 2010,130;2828-2830. (ISI-Indexed)
  • Chik Z, Basu RC, Pendek R, Lee TC and Mohamed Z. 2010. A Bioequivalence Comparison of Two Formulations of Rifampicin (300-vs 150-mg Capsules): An Open-Label, Randomized, Two-Treatment, Two-Way Crossover Study in Healthy Volunteers. CLINICAL THERAPEUTICS 32(10):1822-31 · SEPTEMBER 2010 Impact Factor: 2.59 · DOI: 10.1016/j.clinthera.2010.09.006 (ISI-Indexed)
  • Z. Chik, A.M.Mustafa,Z. Mohamed, T.C.Lee Analysis of captopril in human plasma using gas chromatographiy-mass spectrometry (GCMS) with solid- phase extraction (SPE).Current Analytical Chemistry. 2010,volume 6; 329-333. (ISI-Indexed)

2009
  • Z.Chik, R.C. Basu, R. Pendek, T.C. Lee, Z. Mohamed. Comparative bioavailability study of two salbutamol tablets in healthy adult volunteers.INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS 47(6):413-8 · JULY 2009. Impact Factor: 1.04 · DOI: 10.5414/CPP47413 (ISI-Indexed)
  • Z.Chik , A.Johnston , A.T.Tucker, K.Kirby, C.A.Alam. Correcting Endogenous Concentrations of Testosterone Influence the Bioequivalence and Shows The Superiority of TDS -Testosterone To Androgel. International Journal of Clinical Pharmacology and Therapeutic. Vol 47(4):2009;262-268 (ISI-Indexed)

2007
  • Z. Chik, A. Johnston, A.T.Tucker, R.T.Burn, D.Perrett. Validation and application of capillary electrophoresis for the analysis of lidocaine in a skin tape stripping study. Biomedical Chromatography. 21 (8)2007; 775-779 (ISI-Indexed)

2006
  • Z. Chik, T.D. Lee, D.W. Holt, A. Johnston, A.T. Tucker. Validation of high-performance liquid chromatographic-mass spectrometric (LC-MS-MS) method for the analysis of lidocaine in human plasma. Journal of Chromatographic Sciences.Volume 44; 5, 2006:262-265. (ISI-Indexed)
  • Z. Chik, A. Johnston, A. T. Tucker, S. L. Chew, L. Michaels, C. A. S. Alam Pharmacokinetics of a new testosterone transdermal delivery system, TDS -testosterone in healthy males. British Journal of Clinical Pharmacology, Volume 61 Issue 3 (March 2006). (ISI-Indexed)
  • A.T. Tucker, Z.Chik, L. Michaels, K. Kirby, MP Seed, A.Johnston, and C.A.S. Alam. Study of a combined percutaneous local anaesthetic and the TDS system for venepuncture. Anaesthesia, Volume 61, 2006: 123-126. (ISI-Indexed)

AREAS OF RESEARCH
(Project title), (Role), (From)-(Until), (Level), (Source).



CONSULTATION PROJECT/CONSULTANCY
(Project title), (Role), (From)-(Until), (Organisation).



AWARDS AND RECOGNITIONS
(Name of Award), (Awarding Institution), (Year Awarded), (Level).



PRESENTATIONS
(Title), (Event), (Date Presented), (Organiser), (Level).


ORAL
  • Bioequivalence study of two tablet formulations of captopril (Brand A vs. Brand leader) in healthy volunteers, Annual Scientific Sessions, National Heart Association of Malaysia, 2000-02-08 to 2000-02-09, National Heart Association of Malaysia, (National)
  • Bioequivalence study of two tablet formulations of captopril (Brand B vs. Brand leader) in healthy volunteers, 15th Scientific Meeting of the Malaysian Society of Pharmacology and Physiology(MSPP), 2000-05-16 to 2000-05-17, Malaysian Society of Pharmacology and Physiology(MSPP), (National)
  • Comparative pharmacokinetic assessments of topically applied drugs: Evaluation by dermatopharmacokinetics, microdialysis and systemic measurement., British Pharmacological Society Winter Meeting, 2006-12-21 to 2006-12-22, British Pharmacological Society, (International)
  • Umar Y Mohammed, Awang M Bulgiba, Zamri B chik, Christopher Lee, Devi Peramalah (2012). Is Therapeutic Drug Monitoring (TDM) the best method for measuring adherence level to HAART in HIV positive patients in Kuala Lumpur Malaysia? , APACPH 2012 , 2012-03-22 to 2012-03-25, (International)
  • Physical and Chemical Characteristics of a novel Hamin Insulin Suppositories , 27th Scientific Meeting Malaysian Society of Pharmacology and Physiology , 2013-09-06 to 2013-09-08, International Islamic University of Malaysia, (International)
  • Pharmacokinetics and bioavailability of Mitragynine in Sprague Dawley (SD) Rats using microdialysis, APSA 2016 Annual Conference, 2016-12-01 to 2016-12-05, Australasian Pharmaceutical Science Association, (International)
  • Effect of Cytochrome P450 (CYP2D6) Inhibition in In Vivo toxicity Studies of Mitragyna, International Conference on Toxicology and Clinical Pharmacology, 2017-12-14 to 2017-12-16, Allied Academies, (International)
  • The effect of Piper betle leave extracts on weight, food intake and behaviour of SD Rats by using Elevated Plus-Maze (EPM), 5th International Mediterranean Symposium on Medicinal and Aromatic Plants & 5th International Symposium on Pharmaceutical and Biomedical Sciences April, 24-28, 2019 / Cappadocia - TURKEY, 2019-04-24 to 2019-04-28, MESMAP & ISPBS, (International)
POSTER
  • Pharmacokinetic of two doses of oral captopril in healthy subjects, 16th Scientific Meeting of the Malaysian Society of Pharmacology and Physiology(MSPP), 2001-06-25 to 2001-06-26, Malaysian Society of Pharmacology and Physiology(MSPP), (National)
  • Pharmacokinetic of the new testosterone transdermal delivery system, TDS -Testosterone in healthy subjects, British Pharmacological Society(BPS) Winter Meeting, . December 2004., 2004-12-14 to 2004-12-16, British Pharmacological Society, (International)
  • Study of a combined percutaneous local anaesthetic and the TDS system for venepuncture, 2nd EUFEPS Conference on Optimising Drug Delivery and Formulation, 2005-11-17 to 2005-11-20, The European Federation for Pharmaceutical Sciences, (International)
  • The influence of correcting endogenous concentrations in the bioequivalence assessment of testosterone, British Pharmacological Society(BPS) Winter Meeting, 2005-12-19 to 2005-12-21, British Pharmacological Society
  • A New Testosterone Transdermal Delivery System, TDS -testosterone, Has Superior Pharmacokinetics Compared to an Existing Transdermal Preparation in Healthy Males., Proceedings of the ENDO 2006, The Endocrine Society s 88th Annual Meeting, Boston, Massachusetts, USA, 2006-06-24 to 2006-06-27, The Endocrine Society, (International)
  • Population analysis of pharmacokinetic parameters of captopril in healthy adult Malaysian subjects, 10th SEAWP and 41st ASCEPT Joint Meeting, Adelaide, South Australia., 2007-12-02 to 2007-12-06, 1)South Asian Western Pacific Regional Meeting of Pharmacologists (SEAWP-RMP) 2) Australasian Society of Clinical and Experimental Pharmacologists abd Toxicologists , (International)
  • Bioequivalence study of two tablet formulations of salbutamol in healthy adult subjects., 22nd MSPP Scientific Meeting, Kuala Lumpur April 2008, 2008-04-05 to 2008-04-06, Malaysia Society of Pharmacology and Physiology
  • Bioequivalence study of two tablet formulations of Rifampicin in healthy adult subjects., 33rd Annual Conference of the Malaysian Society For Biochemistry and Molecular Biology, Kuala Lumpur, 2008-08-27 to 2008-08-28, Malaysia Society of Biochemistry and Molecular Biology
  • Analysis of Melamine in Food contact articles available in Malaysian market, 16th World Congress of basic and clinical phramacology, 2010-07-17 to 2010-07-23, Danish Society for Pharmacology, (International)
  • Melamine migration from melamine food contact articles available on the Malaysian market, 16th World Congress of Basic and Clinical Pharmacology , 2010-07-17 to 2010-07-23, Danish Society of Pharmacology and British Pharmacological Society, (International)
  • Analysis of melamine in various food products marketed in Malaysia, 4t Asian Pacific Regional Meeting of ISSX, 2011-04-22 to 2011-04-25, National Cheng Kung University, (International)
  • Analysis of melamine in various food products marketed in Malaysia" has been accepted for poster presentation at the 4th . The meeting will take place in Tainan, Taiwan April 22 - 25, 2011, Asia Pacific Regional ISSX Meeting, 2011-04-22 to 2011-04-25, ISSX, (International)
  • AN EVALUATION OF PARACETAMOL PROTEIN ADDUCTS IN MALAYSIAN PATIENTS WITH ACETAMINOPHEN OVERDOSE, ASCEPT. AUPS, HBPRCA JOINT MEETING, 2011-12-03 to 2011-12-09, ASCEPT AUSTRALIA, (International)
  • Development of a novel HAMIN topical local anaesthetic system for venepuncture. Zamri Chik, Sitti Norkhamdiah and Ibrahim Noordin, Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) Annual Scientific Meeting. , 2013-12-01 to 2013-12-04, ASCEPT, (International)
  • Development of HaminTM Testosterone Transdermal Delivery System and its in vitro and in vivo evaluations, 19th North AmericanISSX/ 29th JSSX Meeting , 2014-10-19 to 2014-10-23, International Society of Xenobiotics, (International)
  • Preparation of Targeted PEG-PLGA Nanoparticles For The Treatment of Cancer Metastasis, World Congress of Clinical Pharmacology, 2018-07-01 to 2018-07-06, IUPHAR, (International)
  • Khat (Catha edulis) Exacerbate Insulin Resistance in A High-Fat Diet/Streptozotocin-Induced Rat Model of Type 2 Diabetes Mellitus, 18th Annual World Congress on Insulin Resistance Diabetes & Cardiovascular Disease, 2020-12-03 to 2020-12-06, The Metabolic Institute of America, (International)

EXPERT LINKAGES
(Linkages Description), (Organisation), (Year of Involvement), (Duration), (Level).



EXPERT/TECHNICAL CONTRIBUTIONS
(Activity), (Organisation), (Role), (From)-(Until), (Level).



EVALUATION ACTIVITIES
(Description), (Evaluation Activity),(Year).



CONTRIBUTION TO SOCIETY
(Contribution To Society), (Level), (Start Date), (End Date).



SUPERVISION


POST GRADUATE STUDENT
(Name of Degree), (Name of Candidates), (Title of Thesis), (Academic Session)

Completed
  • Doctoral Degree (PhD), Abdul Mannan Hassan Saad, Genotoxicity, Teratogenicity and Postnatal Developmental Toxocity Studies of Verbena Officinalis and Capsella Bursa-Pastoris as Traditional Herbals., 2020/2021
  • Doctoral Degree (PhD), Pushpa Gandhi, Preconditioning Prevent Neuroinflammation Induced P53, C-myc, Hsp70 Gene Over-expression., 2017/2018
  • Doctoral Degree (PhD), Mohadeseh Hasanpourghadi, Elucidating The Mechanistic Action of Methyl 2-(5-Fluoro-3-Hydroxyphenyl)-1H-Benzo [d]imidazole-5-Carbonxylate as A Potential Antitumor Agent, 2016/2017
  • Doctoral Degree (PhD), Abu Bakar Elishaq, Effect of Bioactive components of Asparagus Africanus L extracts on reproductive functions in rats, 2014/2015
  • Master Degree, Khamdiah Binti Khodari, Developement of HAMIN topical local anaesthetic system for venepuncture, 2013/2014
  • Master Degree, Rhanye Mac Guad, THE ROLE OF GENETIC POLYMORPHISMS AND HLA VARIANTS ON CLINICAL OUTCOMES IN MALAYSIAN RENAL TRANSPLANT PATIENTS ON CALCINEURIN INHIBITORS, 2012/2013
  • Master Degree, Yusmaidie Aziz, Pharmacokinetic of a novel tetrahydrobiopterine Analogue,, 2012/2013
  • Doctoral Degree (PhD), Zuleen Delina Fasya Binti Abdul Ghani, Assessment of Appetite Suppressant Activities and Lipid Digestion Metabolite from P.betle leaf extracts using metabolomic approach, 2012/2013
  • Master Degree, Ehsan Moghaddam, Determination of the effective route(s) of administration for bioflavonoids as anti-dengue virus agents in animal model, 2012/2013
  • Master Degree, Sritharan Nair, Development of Suppository based for the transdermal delivery of Insulin, 2011/2012
  • Master Degree, Puvanesewari A/pmeganathan, Gamma-Delta Tocotrienol as potential maintenance treatment in women with metastatic breast cancer, 2011/2012
  • Doctoral Degree (PhD), Kong Wai Mun, IN VITRO TOXICOLOGICAL STUDIES OF MITRAGYNA SPECIOSA, 2010/2011
  • Doctoral Degree (PhD), Marzilawati Binti Abd Rahman, Prevalence of Hepatotoxicity & Evaluation of a biomarker in Malaysian adults with paracetamol overdose, 2010/2011
  • Master Degree, Didi Erwandi, Development of Testosterone transdermal drug delivery system, 2008/2009
  • Doctoral Degree (PhD), Umar Yagoub, FACTORS AFFECTING ADHERENCE TO ANTIRETROVIRAL TREATMENT IN HOSPITAL SUNGAI BULUH, 2008/2009

Ongoing
  • Master Degree, Thanusha M Ganesan, ANNEXIN A1 REGULATES THE ANTI-CANCER EFFECTS OF PUNICALAGIN IN COLORECTAL CANCER CELL LINES, 2018/2019
  • Doctoral Degree (PhD), Helmi Bin Sulaiman, ANTIBIOTIC OPTIMIZATION IN THE CRITICALLY III PATIENT, 2018/2019
  • Master Degree, Gan Kok Zheng, FORMULATION DESIGN AND OPTIIMIZATION OF ORODISPERSIBLE TABLETS OF VARDENAFIL HYDROCHLORIDE TRIHYDRATE BY SUBLIMATION METHOD, 2018/2019
  • Master Degree, Wong Fu Shun, BIODISTRIBUTION & PHARMACOKINETICS OF TOCOTRIENOL FOR INTRAVENOUS ADMINISTRATION, 2018/2019
  • Doctoral Degree (PhD), Puvaneswari A/p Meganathan, IMMUNOMODULATORY EFFECTS OF NATURAL COMPOUNDS IN BREAST CANCER, 2018/2019
  • Master Degree, Aidawati Binti Mohamed Shabery, DEVELOPMENT OF NIO-HAMIN? TOPICAL LOCAL ANESTHETIC SYSTEM USING NIOSOME ENCAPSULATED LIDOCAINE AND MEPIVACAINE WITH HAMIN? FOR MINOR SURGERY APPLICATION, 2018/2019
  • Doctoral Degree (PhD), Abdul Samad Ahmed Mokbel Al-salahi, Investigation into The Glycemic Properties of Catha edulis (Khat) Extract in Diabetic-Induced Sprague-Dawley Rats, 2018/2019
  • Doctoral Degree (PhD), Abdulmannan Hasan Saad, Genotoxicity, Teratogenicity and Postnatal Developmental Toxocity Studies of Verbena Officinalis and Capsella Bursa-Pastoris as Traditional Herbals., 2016/2017
  • Doctoral Degree (PhD), Hira Fatima Abbas, Xenobiotics and Breast Cancer Risk and Prognosis., 2015/2016
  • Doctoral Degree (PhD), Hasan Al Moustafa, Development of Targeted Biodegradable Nanoparticles for the Treatment of Cancer Metastasis, 2014/2015
  • Master Degree, Shameem Shariff, Parabens, Body Care Cosmetics, Oestrogenicity and Breast Cancer The determination of parabens concentration in both human breast tumours and normal breast tissue., 2011/2012
FIRST DEGREE/DIPLOMA/PRE-DEGREE
(Course Title), (Academic Session), (No. of Candidates)

Completed
  • Non-invasive transdermal insulin delivery in Rabbits, 2010/2011, 4
  • To assess patient's compliance to the inhalation technique in Obstrutive Lung Disease, 2009/2010, 3
  • Development of HPLC method to measure insulin in human plasma, 2008/2009, 1

Ongoing
  • Development of LCMSMS method for the analysis of Metformin in Plasma, 2010/2011, 1

TEACHING
(Course Title), (Academic Session), (No of Student), (No of Contact Hours).


POST GRADUATE
  • BASIC MEDICAL SCIENCE, 2016/2017(1), 100, 1
  • BASIC MEDICAL SCIENCE, 2016/2017(1,2), 50, 1
  • , 2016/2017(1,2), 50, 1
FIRST DEGREE
  • DRUG ACTION AND DISCOVERY, 2020/2021(1), 47, 9
  • ELEKTIF, 2019/2020(1), 20, 1
  • , 2019/2020(1), 181, 3
  • PHARMACOLOGY, 2019/2020(1), 51, 2
  • University Malaya Medical Programme, 2017/2018(1), 151, 5
  • ADVANCES IN MEDICAL PHARMACOLOGY, 2017/2018(1,2), 5, 6
  • PHARMACOLOGY, 2017/2018(1,2), 49, 7
  • Nursing, 2017/2018, 8, 3
  • University Malaya Medical Programme, 2017/2018(1), 120, 3
  • PHARMACOLOGY IN NURSING, 2016/2017(2), 8, 3
  • Pharmacology, 2016/2017(3), 200, 17
  • CLINICAL PHARMACOKINETICS, 2016/2017(2), 60, 10
  • , 2016/2017(2), 74, 18
  • PHARMACOLOGY, 2016/2017(1,2), 53, 9
  • PHARMACOLOGY IN NURSING, 2016/2017(1), 8, 2
  • University Malaya Medical Programme, 2016/2017(1), 136, 4
  • PRINCIPLES IN PHARMACOLOGY AND TOXICOLOGY, 2016/2017(1), 44, 3
  • PHARMACOLOGY, 2015/2016(1), 56, 6
  • PHARMACOLOGY IN NURSING, 2015/2016(1), 15, 2
  • PRINCIPLE OF DRUG ACTIONS AND PERIPHERAL NERVOUS SYSTEM, 2010/2011, 68, 17
  • Clinicopharmacokinetics, 2010/2011(2), 20, 1
  • Pharmacology for Dentistry, 2010/2011(1,2), 73, 23
  • ADVANCED MEDICAL PHARMACOLOGY, 2010/2011(1), 13, 15
  • ADVANCED MEDICAL PHARMACOLOGY, 2009/2010(1,2), 56, 16
  • PRINCIPLES OF DRUG ACTION & PERIPHERAL NERVOUS SYSTEM, 2009/2010, 70, 14
  • Pharmacology, 2009/2010(1,2), 200, 55
  • Pharmacology for Dentistry, 2009/2010(1,2), 83, 23
  • Pharmacology, 2009/2010(1,2), 200, 51
  • PRINCIPLES OF PHARMACOLOGY AND TOXICOLOGY, 2008/2009(1,2), 36, 11
  • ADVANCED MEDICAL PHARMACOLOGY, 2008/2009(1,2), 36, 10
  • PRINCIPLES OF DRUG ACTION & PERIPHERAL NERVOUS SYSTEM, 2008/2009(1,2), 50, 12
OTHERS
  • GCMS course, 2009/2010, 20, 5