Curriculum Vitae

PROF. DR. ZAMRI BIN CHIK

Professor
  • Department of Pharmacology
    Faculty of Medicine

BIOGRAPHY


Zamri obtained his BSc in Chemistry and MSc in pharmacology from the University of Malaya and later PhD in Clinical Pharmacology from the University of London (UK) in 2007. Soon after completed his doctorate degree, he joined the Department of pharmacology, University of Malaya as a senior lecturer and currently serves as a Professor and head of Pharmacology Department and also Head of University of Malaya Bioequivalence Testing Centre (UBAT). His scope of research includes bioavailability and pharmacokinetic studies in human and animal models, drug delivery systems such as PEG-PLGA nanoparticles for systemic drug delivery, and semi solid formulations for transdermal and topical preparation.  Apart from human clinical trials and preclinical studies in animals, his research also covers the screening and testing of natural product compounds derive from selected local plants. His laboratory also provides services and research in food contaminations, adulterated pharmaceutical products, xenobiotic studies on certain chemicals such as endocrine disruptors in food products, human bodies, etc. using GCMS, HPLC, LCMSMS, etc. Apart from his research activities, he also actively provided consultation to local pharmaceutical companies to conduct testing on pharmaceutical formulations especially for bioequivalence studies, comparative dissolution, etc. His bioequivalence laboratory has conducted more than 40 bioequivalence studies for generic drug formulations and also conducted drug analysis in biological and pharmaceutical formulations. 

 

AREAS OF EXPERTISE


  • CLINICAL PHARMACOLOGY
    Pharmacokinetic and pharmacodynamic studies;PK/PD modelling,etc. Phase I & II clinical trials
  • DRUG DELIVERY: NANOFORMULATIONS AND TRANSDERMAL DRUG DELIVERY SYSTEM
    Development of transdermal delivery systems
  • TRADITIONAL MEDICINE AND NATURAL PRODUCT
    Pharmacological activity and animal studies of active compounds from local plants for medicinal purposes
  • TOXICOLOGY
    Food additives and toxicology
  • DRUG REGULATORY AND SUBMISSIONS
    Bioequivalence study for generic drug substitutions

ACADEMIC QUALIFICATION


  • Expert Training
    Ibm Corp. Almaden Research Centre, San Jose, California
  • Doctoral Degree (PhD), (Clinical Pharmachology)
    Queen Mary College, London
  • PhD(2007), (Clinical Pharmacology/ Pharmacokinetic)
    University of London, UK
  • MPhil(2001), (Pharmacokinetic and Drug Analysis)
    Universiti Malaya (UM)
  • BSc(1996), (Kimia)
    Universiti Malaya (UM)
  • DipSc(1992), (Sains)
    Universiti Teknologi Mara (Uitm)

ADMINISTRATIVE DUTIES


  • Head of Unit
    18 Nov 2016 - 23 Oct 2029 (University Malaya)
  • Technical Manager/Approved Signatory for UBAT (University of Malaya Bioequivalence and Testing Centre)
    01 Apr 2009 - present (University Malaya)
  • Quality Manager
    06 Jun 2007 - present (Department of Pharmacology, Faculty of Medicine)
  • Course coordinator for the 2nd Year Bachelor of Dentistry
    16 Jun 2008 - present (University Malaya)
  • Programme Coordinator
    04 Sep 2013 - present (University Malaya)
  • Ahli jawatankuasa penilaian dan pemantauan geran penyelidikan (JPPGP) Fakulti Perubatan
    05 May 2014 - present (University Malaya)
  • Programme Coordinator
    01 Sep 2014 - present (Department of Pharmacology, Faculty of Medicine)
  • Ahli jawatankuasa kecil ubat-ubatan and terapeutik (JKU&T)
    15 Sep 2016 - present (University Malaya)
  • Head of Department
    01 Feb 2022 - 31 Dec 2023 (Department of Pharmacology, Faculty of Medicine)
  • Head of Department
    01 Feb 2022 - 31 Dec 2023 (University Malaya)
  • Head of Department
    01 Oct 2021 - 31 Jan 2022 (Department of Pharmacology, Faculty of Medicine)
  • Ahli jawatankuasa Tabung UMSC Care
    01 Oct 2020 - 30 Sep 2022 (University Malaya)
  • Head of Department
    01 Feb 2020 - 25 Apr 2021 (Department of Pharmacology, Faculty of Medicine)
  • Director, University of Malaya Bioequivalence Testing Centre
    01 Aug 2020 - 31 Dec 2021 (University Malaya)
  • Ahli jawatankuasa Tabung Toh Puan Dr Hajjah Aishah Ong
    01 Apr 2018 - 31 Mar 2020 (University Malaya)
  • Head of Department
    01 Aug 2018 - 11 Nov 2018 (Department of Pharmacology, Faculty of Medicine)
  • Head of Department
    01 Aug 2016 - 31 Jul 2018 (Department of Pharmacology, Faculty of Medicine)
  • Head of Unit
    27 Sep 2016 - 31 Jul 2018 (University Malaya)
  • Ahli jawatankuasa Etika Penyelidikan Perubatan
    01 Aug 2016 - 31 Dec 2016 (University Malaya)
  • Acting Head of Department
    15 Jun 2012 - 15 Jun 2012 (University Malaya)
  • Acting Head of Department
    23 May 2012 - 25 May 2012 (University Malaya)
  • Acting Head of Department
    30 Apr 2012 - 30 Apr 2012 (University Malaya)
  • Acting Head of Department
    02 Feb 2012 - 03 Feb 2012 (University Malaya)
  • Acting Head of Department
    19 Dec 2011 - 21 Dec 2011 (University Malaya)
  • Acting Head of Department
    13 Dec 2010 - 13 Dec 2010 (University Malaya)
  • Acting Head of Department
    02 Jul 2010 - 05 Jul 2010 (University Malaya)
  • Secretary for the 22nd. Scientific Meeting of Malaysian Society of Pharmacology and Physiology (MSPP)
    13 Jun 2007 - 11 Apr 2008 (University Malaya)

MEMBERSHIPS


  • AHLI MAJLIS PROFESSOR NEGARA, MEMBER
    Since 2023 (National)
  • MEMBER OF THE CONTROL RELEASE SOCIETY-MALAYSIA LOCAL CHAPTER, MEMBER
    Since 2021 (National)
  • BRITISH PHARMACOLOGICAL SOCIETY FULL MEMBERSHIP, MEMBER
    Since 2017 (International)
  • MEMBER OF THE MALAYSIAN INSTITUTE OF CHEMISTRY, MEMBER
    2023 to 2023 (National)
  • MEMBER OF THE MALAYSIAN INSTITUTE OF CHEMISTRY MALAYSIA, MEMBER
    2022 to 2022 (National)
  • ASSOCIATE MEMBER (CHEMIST), MEMBER
    2021 to 2021 (National)

AWARD AND STEWARDSHIP


  • Sijil Penghargaan Pakar panel of Expert (POE) Kajian Klinikal First In Human
    NPRA, 2022 (National)
  • JAWATANKUASA PENILAIAN PERMOHONAN MALAYSIA-FRANCE BILATERAL RESEARCH COLLABORATION 2021 (MATCH)
    KPT, 2021 (National)
  • Panel Reviewer for UMSC CARE Funds
    University Malaya, 2020 (University)
  • Ahli jawatankuasa Tabung UMSC
    University Malaya, 2020 (University)
  • Ahli jawatankuasa Penilaian Dana Penyelidikan kementerian Pengajian Tinggi
    Kementerian Pengajian Tinggi, 2020 (National)
  • Penilai Harta Intelek
    University Sains Islam Malaysia, 2020 (National)
  • Panel of Expert for First in Human Studies
    Ministry of Health, 2020 (National)
  • Panel Penilai Hubert Curien Partenrship-Hibiscus 2020
    Kementerian Pendidikan Malaysia, 2020 (National)
  • Reviewer Board of Research Grant
    Jazan University Kingdom of Saudi Arabia, 2020 (International)
  • Ahli Jawatankuasa National Committee for Clinical Research (NCCR)
    Ministry of Health, 2019 (National)
  • Joint Study Agreement
    IBM USA, 2019 (International)
  • Appointment as trainee technical assessor under Skim Akreditasi Makmal Malaysia
    Standard Malaysia, 2019 (National)
  • Reviewer of Biomedical Chromatography
    Wiley , 2019 (International)
  • Pelantikan Perunding projek kepada Monash University
    University Malaya, 2018 (University)
  • Perlantikan Sebagai perunding projek
    University Malaya, 2018 (University)
  • Perlantikan sebagai Perunding Projek
    University Malaya, 2018 (University)
  • Hadiah Latihan Sub kepakaran
    Kementerian Pendidikan Malaysia, 2018 (National)
  • Jawatankuasa Tabung Toh Puan Dr Hajjah Aishah Ong
    University Malaya, 2018 (University)
  • Ahli Jawatankuasa Pakar Aditif Makanan
    Ministry of Health, 2018 (National)
  • PHD thesis external examiner
    The University of Southern Queensland, Australia, 2017 (International)
  • Juruanalisis di bawah akta Makanan
    Kementerian Kesihatan Malaysia, 2017 (International)
  • Winner of Dato Dr Mahmood Merican Medical Research Grant (MMRG)
    University Malaya, 2016 (University)
  • EXCELLENCE SERVICE AWARD
    University of Malaya, 2014 (University)
  • CERTIFICATE OF EXCELLENT SERVICE
    University of Malaya, 2013 (University)
  • Appointed as module moderator for Open University Malaysia
    Open University Malaysia, 2011 (National)
  • EXCELLENCE SERVICE AWARD
    University of Malaya, 2010 (University)
  • Best Poster Presenter during 22nd Scientific Meeting of MSPP
    Malaysian Society of Pharmacology and Physiology, 2008 (International)

PUBLICATIONS


Article in Journal
WoS
  1. Abolmaesoomi, Mitra; Junit, Sarni Mat; Ali, Johari Mohd; Bin Chik, Zamri; Aziz, Azlina Abdul (2023). Effects of polyphenolic-rich extracts from Citrus hystrix on proliferation and oxidative stress in breast and colorectal cancer, TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI. . doi:10.1515/tjb-2022-0062
  2. Almoustafa, Hassan A.; Alshawsh, Mohammed Abdullah; Al-Suede, Fouad Saleih R.; Alshehade, Salah Abdulrazak; Majid, Amin Malik Shah Abdul; Chik, Zamri (2023). The Chemotherapeutic Efficacy of Hyaluronic Acid Coated Polymeric Nanoparticles against Breast Cancer Metastasis in Female NCr-Nu/Nu Nude Mice, POLYMERS. 15(2). doi:10.3390/polym15020284
  3. Shabery, Aidawati Mohamed; Widodo, Riyanto Teguh; Chik, Zamri (2023). Formulation and In Vivo Pain Assessment of a Novel Niosomal Lidocaine and Prilocaine in an Emulsion Gel (Emulgel) of Semisolid Palm Oil Base for Topical Drug Delivery, GELS. 9(2). doi:10.3390/gels9020096
  4. Geo, Hui Nee; Murugan, Dharmani Devi; Chik, Zamri; Norazit, Anwar; Foo, Yiing Yee; Leo, Bey Fen; Teo, Yin Yin; Kadir, Sharifah Zamiah Syed Binti Syed Abdul; Chan, Yinghan; Chai, Hann Juang; Medel, Maria; Abdullah, Nor Azizan; Johns, Edward J.; Vicent, Maria J.; Chung, Lip Yong; Kiew, Lik Voon (2022). Renal Nano-drug delivery for acute kidney Injury: Current status and future perspectives, JOURNAL OF CONTROLLED RELEASE. 343, 237-254. doi:10.1016/j.jconrel.2022.01.033
  5. Gopinath, V; Kamath, S. Manjunath; Priyadarshini, S.; Chik, Zamri; Alarfaj, Abdullah A.; Hirad, Abdurahman H. (2022). Multifunctional applications of natural polysaccharide starch and cellulose: An update on recent advances, BIOMEDICINE & PHARMACOTHERAPY. 146. doi:10.1016/j.biopha.2021.112492
  6. Kamran, Sareh; Sinniah, Ajantha; Chik, Zamri; Alshawsh, Mohammed Abdullah (2022). Diosmetin Exerts Synergistic Effects in Combination with 5-Fluorouracil in Colorectal Cancer Cells, BIOMEDICINES. 10(3). doi:10.3390/biomedicines10030531
  7. Than, Nam; Chik, Zamri; Bowers, Amy; Bozano, Luisa; Adebiyi, Aminat (2022). Quantitation of ethanol in UTI assay for volatile organic compound detection by electronic nose using the validated headspace GC-MS method, PLOS ONE. 17(10). doi:10.1371/journal.pone.0275517
  8. Almoustafa, H. A., Alshawsh, M. A., & Chik, Z. (2021). Targeted polymeric nanoparticle for anthracycline delivery in hypoxia-induced drug resistance in metastatic breast cancer cells. Anti-Cancer Drugs, 32(7), 745-754. doi: 10.1097/cad.0000000000001065
  9. Alsalahi, A., Chik, Z., Mohamed, Z., Giribabu, N., & Alshawsh, M. A. (2021). Cathinone: An alkaloid of Catha edulis (Khat) exacerbated hyperglycemia in diabetes-induced rats. Saudi Journal of Biological Sciences, 28(8), 4633-4643. doi: 10.1016/j.sjbs.2021.04.072
  10. Alshawsh, Mohammed A.; Alsalahi, Abdulsamad; Mohamed, Zahurin; Giribabu, Nelli; Chik, Zamri (2021). Khat (Catha edulis) Exacerbate Insulin Resistance in A High-Fat Diet/Streptozotocin-Induced Rat Model of Type 2 Diabetes Mellitus, METABOLISM-CLINICAL AND EXPERIMENTAL. 116, 32-32. doi:10.1016/j.metabol.2020.154546
  11. Beishenaliev, A., Faruqu, F. N., Leo, B. F., Lit, L. C., Loke, Y. L., Chang, C. C., . . . Kiew, L. V. (2021). Facile synthesis of biocompatible sub-5 nm alginate-stabilised gold nanoparticles with sonosensitising properties. Colloids and Surfaces a-Physicochemical and Engineering Aspects, 627, 10. doi: 10.1016/j.colsurfa.2021.127141
  12. Gan, K. Z., Widodo, R. T., Chik, Z., Teh, L. K., Rofiee, M. S., & Yusof, M. I. M. (2021). Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Vardenafil and Its Application of Bioequivalence. International Journal of Analytical Chemistry, 2021, 10. doi: 10.1155/2021/5590594
  13. Sangaran, P. G., Ibrahim, Z. A., Chik, Z., Mohamed, Z., & Ahmadiani, A. (2021). LPS Preconditioning Attenuates Apoptosis Mechanism by Inhibiting NF-kappa B and Caspase-3 Activity: TLR4 Pre-activation in the Signaling Pathway of LPS-Induced Neuroprotection. Molecular Neurobiology, 58(5), 2407-2422. doi: 10.1007/s12035-020-02227-3
  14. Sangaran, P. G., Ibrahim, Z. A., Chik, Z., Mohamed, Z., & Ahmadiani, A. (2021). Lipopolysaccharide Pre-conditioning Attenuates Pro-inflammatory Responses and Promotes Cytoprotective Effect in Differentiated PC12 Cell Lines via Pre-activation of Toll-Like Receptor-4 Signaling Pathway Leading to the Inhibition of Caspase-3/Nuclear Factor-kappa appa B Pathway. Frontiers in Cellular Neuroscience, 14, 29. doi: 10.3389/fncel.2020.598453
  15. Wang, L. S., Aziz, Z., & Chik, Z. (2021). Disposal practice and factors associated with unused medicines in Malaysia: a cross-sectional study. BMC Public Health, 21(1), 10. doi: 10.1186/s12889-021-11676-x
  16. El-Ishaq, A., Alshawsh, M. A., Mun, K. S., & Chik, Z. (2020). Biochemical and toxicological effects of methanolic extract of Asparagus africanus Lam in Sprague-Dawley rats. PeerJ, 8, 15. doi: 10.7717/peerj.9138
  17. Ganesan, T., Sinniah, A., Chik, Z., & Alshawsh, M. A. (2020). Punicalagin Regulates Apoptosis-Autophagy Switch via Modulation of Annexin A1 in Colorectal Cancer. Nutrients, 12(8), 17. doi: 10.3390/nu12082430
  18. Ganesan, T., Sinniah, A., Ibrahim, Z. A., Chik, Z., & Alshawsh, M. A. (2020). Annexin A1: A Bane or a Boon in Cancer? A Systematic Review. Molecules, 25(16), 15. doi: 10.3390/molecules25163700
  19. Aziz, M. Y., Chik, Z. Bioanalysis of tetrahydrobiopterin with liquid chromatographic-mass spectrometric and its application for pharmacokinetics in apolipoprotein E knockout mice. Journal of Liquid Chromatography Related Technologies, 8. doi:10.1080/10826076.2019.1625376
  20. El-Ishaq, A., Alshawsh, M. A., Bin Chik, Z. (2019). Evaluating the oestrogenic activities of aqueous root extract of Asparagus africanus Lam in female Sprague-Dawley rats and its phytochemical screening using Gas Chromatography-Mass Spectrometry (GC/MS). Peerj, 7, 16. doi:10.7717/peerj.7254
  21. El-Ishaq, A., Alshawsh, M. A., Mun, K. S., Chik, Z. (2019). Phytochemical screening and anti-implantation activity of Asparagus africanus root extract in female Sprague-Dawley rats. Revista Brasileira De Farmacognosia-Brazilian Journal of Pharmacognosy, 29(5), 621-630. doi:10.1016/j.bjp.2019.06.003
  22. Fateh, A. H., Mohamed, Z., Chik, Z., Alsalahi, A., Zain, S. R. M., Alshawsh, M. A. (2019). Mutagenicity and and genotoxicity effects of Verbena officinalis leaves extract in Sprague-Dawley Rats. Journal of Ethnopharmacology, 235, 88-99. doi:10.1016/j.jep.2019.02.007
  23. Fateh, A. H., Mohamed, Z., Chik, Z., Alsalahi, A., Zin, S. R. M., Alshawsh, M. A. (2019). Prenatal developmental toxicity evaluation of Verbena officinalis during gestation period in female Sprague-Dawley rats. Chemico-Biological Interactions, 304, 28-42. doi:10.1016/j.cbi.2019.02.016
  24. Ghani, Z., Ab Rashid, A. H., Shaari, K., Chik, Z. (2019). Urine NMR Metabolomic Study on Biochemical Activities to Investigate the Effect of P. betle Extract on Obese Rats. Applied Biochemistry and Biotechnology, 189(2), 690-708. doi:10.1007/s12010-019-03042-w
  25. Alsalahi, A., Alshawsh, M. A., Chik, Z., Mohamed, Z. (2018). Effect of Catha edulis (khat) on pancreatic functions in streptozotocin-induced diabetes in male Sprague-Dawley rats. Experimental Animals, 67(4), 517-526. doi:10.1538/expanim.18-0057
  26. Almoustafa, H. A., Alshawsh, M. A., Chik, Z. (2017). Technical aspects of preparing PEG-PLGA nanoparticles as carrier for chemotherapeutic agents by nanoprecipitation method. International Journal of Pharmaceutics, 533(1), 275-284. doi:10.1016/j.ijpharm.2017.09.054
  27. Chai, H. J., Kiew, L. V., Chin, Y. N., Norazit, A., Noor, S. M., Lo, Y. L., Looi, C. Y., Lau, Y. S., Lim, T. M., Wong, W. F., et al. (2017). Renal targeting potential of a polymeric drug carrier, poly-L-glutamic acid, in normal and diabetic rats. International Journal of Nanomedicine, 12, 577-591.
  28. Khodari, S. N. K., Noordin, M. I., Chan, L., Chik, Z. (2017). In vitro and in vivo Evaluation of New Topical Anaesthetic Cream Formulated with Palm Oil Base. Current Drug Delivery, 14(5), 690-695. doi: 10.2174/1567201813666160801113302.
  29. Kong, W. M., Chik, Z., Mohamed, Z., Alshawsh, M. A. (2017). Physicochemical Characterization of Mitragyna speciosa Alkaloid Extract and Mitragynine using In Vitro High Throughput Assays. Combinatorial Chemistry High Throughput Screening, 20(9), 796-803. doi:10.2174/1386207320666171026121820
  30. Kong, W. M., Mohamed, Z., Alshawsh, M. A., Chik, Z. (2017). Evaluation of pharmacokinetics and blood-brain barrier permeability of mitragynine using in vivo microdialysis technique. Journal of Pharmaceutical and Biomedical Analysis, 143, 43-47.
  31. Ghani, Z., Husin, J. M., Ab Rashid, A. H., Shaari, K., Chik, Z. (2016). Biochemical studies of Piper betle L leaf extract on obese treated animal using 1H-NMR-based metabolomic approach of blood serum samples. Journal of Ethnopharmacology, 194, 690-697.
  32. Mac Guad, R., Zaharan, N. L., Chik, Z., Mohamed, Z., Peng, N. K., Adnan, W. (2016). Effects of CYP3A5 Genetic Polymorphism on the Pharmacokinetics of Tacrolimus in Renal Transplant Recipients, Transplantation Proceedings. 48(181-87), Article
ESCI
  1. Lim, S. P.; Aalam, N. Zainal; Chik, Z.; Musa, S. (2023). The pharmacokinetics of 38% silver diamine fluoride in healthy children with dental caries: a quasi-experimental study, EUROPEAN ARCHIVES OF PAEDIATRIC DENTISTRY. . doi:10.1007/s40368-023-00837-8
Others
  1. Leong Seng Wang, Zoriah Aziz and Zamri Chik (2021), Disposal practice and factors associated with unused medicines in Malaysia: A cross-sectional study; BMC Public Health, published open access 16 September 2021
  2. Pushpa Gandi Sangaran, Zaridatul Aini Ibrahim, Zamri Chik, Zahurin Mohamed, Abolhassan Ahmadiani. LPS preconditioning attenuate apoptosis mechanism by inhibiting NF- B and caspase-3 activity : TLR4 pre-activation in the signaling pathway of LPS induced neuroprotection. Molecular Neurobiology. Published online 9 January 2021
  3. Pushpa Gandi Sangaran, Zaridatul Aini Ibrahim, Zamri Chik, Zahurin Mohamed, Abolhassan Ahmadiani. Lipopolysaccharide preconditioning attenuates pro-inflammatory responses and promotes cytoprotective effect in differentiated PC12 cell lines via pre-activation of Toll-Like Receptor-4 signaling pathway leading to the inhibition of caspase-3/Nuclear Factor- appa B pathway. Frontiers in Cellular Neuroscience. Published 22 January 2021
  4. THANUSHA GANESAN, AJANTHA SINNIAH *, ZAMRI CHIK, MOHAMMED ABDULLAH ALSHAWSH. Punicalagin regulates apoptosis-autophagy switch via modulation of Annexin A1 in colorectal cancer. Nutrients. Nutrients 2020, 12, 2430;
  5. Abdulmannan H. Fateha, Zahurin Mohameda, Zamri Chika, Abdulsamad Alsalahia, Siti Rosmani Md Zainb, Mohammed A. Alshawsha. Mutagenicity and genotoxicity effects of Verbena officinalis leaves extract in Sprague-Dawley Rats. Journal of Ethnopharmacology. 235 (2019), 88-99
  6. R, Mac Guad et al. SAFETY AND EFFICACY OF TWO TACROLIMUS FORMULATIONS (PROGRAF AND ADVAGRAF ) IN MALAYSIAN RENAL TRANSPLANT PATIENTS: A COMPARATIVE STUDY. Journal of Health and Translational Medicine, [S.l.], v. 22, n. 1, may 2019.
  7. Abdullah, N. L., Gunasekaran, R., Mohd-Zin, S. W., Lim, B. H., Maniam, P., Mohd-Salleh, A. S., Thong M.K., Chik. Z., Nordin N., Omar Z.,Engkasan, J. P., Ganesan D., Aiezzah Z. N., Annuar A.A., & Abdul Aziz N. M. (2018). Cranial neural tube defect after trimethoprim exposure. BMC Research Notes, 11(1), 475.
  8. Effect of Catha edulis (Khat) on Pancreatic Functions in Streptozotocin-Induced Diabetes in Male Sprague-Dawley Rats
  9. Chai, H.J., Kiew, L.V., Chin, Y., Norazit, A., Mohd, Noor. S., Lo, Y.L., Looi, C.Y., Lau, Y.S., Lim, T.M., Wong, W.F., Abdullah, N.A., Abdul Sattar, M.Z., Johns, E.J., Chik, Z., Chung, L.Y. (2017) Renal Targeting Potential of a Polymeric Drug Carrier Poly-L-Glutamic Acid (PG) in Normal and Diabetic Rats. International Journal of Nanomedicine, 2017(12): 577-591, DOI: 10.2147/IJN.S111284 (IF: 4.38, Tier 1)
  10. Hassan A. Almoustafa, Mohammed A. Alshawsh, Zamri Chik. Technical Aspects of Preparing PEG-PLGA Nanoparticles as Carrier for Chemotherapeutic Agents by Nanoprecipitation Method. International Journal of Pharmaceutics (2017). Volume 533, Page 275-284
  11. Wai Mun Kong, Zamri Chik, Zahurin Mohamed and Mohammed A. Alshawsh 2017. Physicochemical Characterization of Mitragyna speciosa Alkaloid Extract and Mitragynine Using In Vitro High Throughput Assays. Combinatorial Chemistry & High Throughput Screening. 20, 1-9. DOI;10.2174/1386207320666171026121820
  12. R.M. Guad, N.L. Zaharan, Z. Chik, Z. Mohamed, B.S. Haerian, K.P. Ng, W.A.H. Wan Md Adnan. Effects of CYP3A5 Genetic Polymorphism on the Pharmacokinetics of Tacrolimus in Renal Transplant Recipients. TRANSPLANTATION PROCEEDINGS 48(1):81-87 FEBRUARY 2016. Impact Factor: 0.98 DOI: 10.1016/j.transproceed.2016.01.001 (ISI-Cited Publication)
  13. A new formulation of Gamma Delta Tocotrienol has superior bioavailability compared to an existing Tocotrienol Rich Fraction in healthy human subjects.Puvaneswari Meganathan, Rafid Salim Jabir, Ho Gwo Fuang, Nirmala Bhoo-Pathy, Roma Basu Choudhury, *Nur Aishah Taib1, Kalanithi Nesaretnam5, Zamri Chik. Article in press (Nature Scientific Report (2015)
  14. Didi Erwandi Mohamad Haron, Zamri Chik, Mohamed Ibrahim Noordin, Zahurin Mohamed. In Vitro and In Vivo Evaluation of A Novel Testosterone Transdermal Delivery System TTDS) Using Palm Oil Base. Iranian Journal of Basic Medical Sciences.Dec;18(12):1167-75, 2015
  15. Sritharan Nair, Zamri Chik, and Mohamed Ibrahim Noordin. In Vitro characteristics of insulin suppository developed using palm oil base (HAMIN) and its hypoglycaemic effect on rabbits. . Frontiers in Life Science Published online 10 July 2015, Volume 8, Issue 3, 2015. ISI cited publication
  16. Chik , Deril N, Didi EMH, Basu RC, Ratnasingam J, and Z Mohamed . A Bioequivalence Comparison of Two Captopril Formulations (25 mg Tablets): An Open-Label, Randomized, Two-Treatment, Two-Way Crossover Study in Healthy Volunteers. Journal of Bioequivalence and Bioavailability. Journal of Bioequivalence and Bioavailability2014.Volume 6(3): 080-085 (2014) - 080
  17. Ehsan Moghaddam, Boon-Teong Teoh, Sing-Sin Sam, Rafidah Lani, Pouya Hassandarvish, Zamri Chik, Andrew Yueh, Sazaly Abubakar, and Keivan Zandi.Baicalin, a metabolite of baicalein with antiviral activity against dengue virus Scientific Report, Nature Publishing. 4:5452 (2014)
  18. Shiau Hui Diong1*, Nor Shuhadah Mohd Yusoff2, Maw Shin Sim1, Raja Elina Raja Aziddin2, Zamri Chik1, Rusdi Abdul Rashid3, Norliza Chemi4, Zahurin Mohamed1 Quantitation of methadone and its metabolite in patients under maintenance treatment. Journal of Analytical Toxicology, 2014. Accepted for publication.Published Online on August 8 2014
  19. Bulgiba, A., Mohammed, U. Y., Chik, Z., Lee, C., Peramalah, D. 2013. How well does self-reported adherence fare compared to therapeutic drug monitoring in HAART? Preventive Medicine. (Tier 1, Impact Factor = 3.496)
  20. Hemmati, F. Dargahi, L. Nasoohi, S. Omidbakhsh, R. Mohamed, Z. Chik, Z. Naidu, M. & Ahmadiani, A. 2013. Neurorestorative effect of FTY720 in a rat model of Alzheimer's disease: Comparison with Memantine. Behavioural brain research, 252 : 415-421.
  21. T Hairin, A.R.Marzilawati, EMH Didi , S. Mahadeva, YK Lee, N Abd Rahman, A.M.Mustafa and Z.Chik*.Quantitative LC-MS/MS Analysis of Acetaminophen Cysteine Adducts (APAP- CYS) and Its Application In Acetaminophen Overdose Patients. Analytical Methods 2013;5(8);1955-1964
  22. Umar Yagoub, Awang Bulgiba, Peramalah D, Didi E, Mustafa A,Chris-topher Lee, Chik Zamri 2012. Factors affecting adherence level to HAART (Adherence predictors) in Kuala Lumpur, Malaysia. Life Science Journal 2012;9(4) 3600-3(ISI Cited Publication)
  23. Umar Yagoub, Bulgiba AM, Didi EM, Mustafa Ali, Peramalah D, Lee C, Chik Z. Analysis of Nevirapine and Lamivudine in human plasma of HIV infected patients by high-performance liquid chromatographic-mass spectrometric (LC-MS-MS). Life Sci J 9(4)2012; 4637- 4645(ISI Cited Publication).
  24. Chik, Z., Haron, D. E. M., Ahmad, E. D., Taha, H., Mustafa, A. M. 2011. Analysis of melamine migration from melamine food contact articles Food Additives and Contaminants Part a-Chemistry Analysis Control Exposure Risk Assessment. 287 (2011)
  25. Kong, W. M., Chik, Z., Ramachandra, M., Subramaniam, U., Aziddin, R. E. R., Mohamed, Z. 2011. Evaluation of the Effects of Mitragyna speciosa Alkaloid Extract on Cytochrome P450 Enzymes Using a High Throughput Assay Molecules. (Tier 2, Impact Factor = 1.988 )
  26. Umar Yagoub, Awang M Bulgiba,Didi EM, Mustafa AM, Peramalah D, Chris-topher Lee, Chik Z, 2011. Validation and analysis of Efavirenz in human plasma using high-performance liquid chromatographic-mass spectrometric (LC-MS-MS).International journal of natural product and pharmaceutical sciences Vol. 2(2), pp 72-81.
  27. Chik Z, Basu RC, Pendek R, Lee TC and Mohamed Z. 2010. A Bioequivalence Comparison of Two Formulations of Rifampicin (300-vs 150-mg Capsules): An Open-Label, Randomized, Two-Treatment, Two-Way Crossover Study in Healthy Volunteers. CLINICAL THERAPEUTICS 32(10):1822-31 SEPTEMBER 2010 Impact Factor: 2.59 DOI: 10.1016/j.clinthera.2010.09.006
  28. L Chan, Z Chik, HD Mohamad, YH Phang, G Ong, MM Ali. 2010. Pharmacokinetics of dexmedetomidine infusion in intensive care patients.Anaesthesia & Intensive Care; vol 38(6): 1119
  29. Z. Chik, A.M.Mustafa,Z. Mohamed, T.C.Lee Analysis of captopril in human plasma using gas chromatographiy-mass spectrometry (GCMS) with solid- phase extraction (SPE).Current Analytical Chemistry. 2010,volume 6; 329-333.
  30. Zamri Chik, Arthur T Tucker, Jukian I Shiel, David J Collier, David Perrett, Terrence D. Lee and Atholl Johnston. Comparative Pharmacokinetic Assessments of Topical Drugs: Evaluation by Dermatopharmacokinetics, Microdialysis, and Systemic Measurement. Journal of Investigative Dermatology. 2010,130;2828-2830.
  31. Z.Chik , A.Johnston , A.T.Tucker, K.Kirby, C.A.Alam. Correcting Endogenous Concentrations of Testosterone Influence the Bioequivalence and Shows The Superiority of TDS -Testosterone To Androgel. International Journal of Clinical Pharmacology and Therapeutic. Vol 47(4):2009;262-268
  32. Z.Chik, R.C. Basu, R. Pendek, T.C. Lee, Z. Mohamed. Comparative bioavailability study of two salbutamol tablets in healthy adult volunteers.INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS 47(6):413-8 JULY 2009. Impact Factor: 1.04 DOI: 10.5414/CPP47413
  33. Z. Chik, A. Johnston, A.T.Tucker, R.T.Burn, D.Perrett. Validation and application of capillary electrophoresis for the analysis of lidocaine in a skin tape stripping study. Biomedical Chromatography. 21 (8)2007; 775-779
  34. A.T. Tucker, Z.Chik, L. Michaels, K. Kirby, MP Seed, A.Johnston, and C.A.S. Alam. Study of a combined percutaneous local anaesthetic and the TDS system for venepuncture. Anaesthesia, Volume 61, 2006: 123-126.
  35. Z. Chik, A. Johnston, A. T. Tucker, S. L. Chew, L. Michaels, C. A. S. Alam Pharmacokinetics of a new testosterone transdermal delivery system, TDS -testosterone in healthy males. British Journal of Clinical Pharmacology, Volume 61 Issue 3 (March 2006).
  36. Z. Chik, T.D. Lee, D.W. Holt, A. Johnston, A.T. Tucker. Validation of high-performance liquid chromatographic-mass spectrometric (LC-MS-MS) method for the analysis of lidocaine in human plasma. Journal of Chromatographic Sciences.Volume 44; 5, 2006:262-265.
Article in Proceeding
  1. Zamri Chik, Hassan Al Moustafa, MA Alswash. The chemotherapeutic efficacy of hyaluronic acid coated polymeric nanoparticles against breast cancer: In vivo study. 2nd International Conference on Pharmaceutics & Novel Drug Delivery Systems. 14-15 November 2022, Dubai, UAE

RESEARCH PROJECT


National
  1. 2022 - 2025, Fundamental Research Grant Scheme (FRGS)
    Fundamental Investigation On The Nanocarrier-Assisted Rapid Drug Urothelial Mucopenetration And Ultrasound-Regulated Tumour-Selective Bladder Drug Delivery To Improve Intravesical Bladder Cancer Therapy ( Co-Researcher)
  2. 2021 - 2024, Prototype Research Grant Scheme (PRGS)
    Development Of Industrial Prototype Of Polymeric Targeted And Non Targeted Nanoparticle Formulation For The Treatment Of Cancer: Preclinical And Technical Evaluation ( Principal Investigator(PI))
  3. 2022 - 2024, Others MOHE - Top 100 (IIRG)-FNW
    In-vitro and In-vivo Evaluations of New Formulations of Novel Metformin-based Compound Orally Dispersible Tablets ( Co-Researcher)
  4. 2022 - 2024, UM International Collaboration Grant
    Designing Nanostructured Lyotropic Liquid Crystals Of Monooleate-based Fatty Esters For Drug Encapsulation And Delivery ( Co-Researcher)
  5. 2022 - 2024, UM International Collaboration Grant
    The Development of ultrasound-responsive multistage-ultrasmall nanoparticles for improved tumour penetration and renal clearance ( Co-Researcher)
  6. 2022 - 2024, Others MOHE - Top 100 (IIRG)-HWB
    WP2: Smart Twin Block Appliance with Integrated Sensor and TargetedOral Therapeutic-Delivery System for Improving Treatment Effectiveness ( Co-Researcher)
  7. 2019 - 2023, Fundamental Research Grant Scheme (FRGS)
    Synergistic Effects Of 5-fluorouracil In Combination With Esculetin On Colorectal Cancer And Its Underlying Molecular Mechanism Of Action ( Co-Researcher)
  8. 2020 - 2023, RU Geran - Fakulti Program
    Understanding Release Characteristics And Pharmacokinetics Study Of Encapsulated Nanoparticle Gel Transdermal Delivery Of Testosterone ( Co-Researcher)
  9. 2020 - 2023, RU Geran - Fakulti Program
    Safety Of Intraoperative Intravenous Lignocaine Infusion In Adolescent Idiopathic Scoliosis Surgery ?a Pharmacokinetic Study ( Principal Investigator(PI))
  10. 2018 - 2021, RU Geran - Fakulti Program
    Nano-drug-carrier Assisted Targeted Drug Delivery For The Prevention And Attenuation Of Acute Kidney Injury: A Mechanistic Proof-of-concept In Vivo Study ( Co-Researcher)
  11. 2014 - 2019, Others MOHE
    Geran Sanjungan Penyelidikan MO018-2014 ( Principal Investigator(PI))
  12. 2015 - 2018, Postgraduate Research Grant (PPP) - Research
    Effect Of Bioactive Components Of Asparagus Africanus Extracts On Reproductive Functions In Rats ( Principal Investigator(PI))
  13. 2014 - 2017, Fundamental Research Grant Scheme (FRGS)
    Development Of Targeted Biodegradable Nanoparticles For The Treatment Of Cancer Metastasis ( Principal Investigator(PI))
  14. 2015 - 2017, Postgraduate Research Grant (PPP) - Research
    Preconditioning Prevent Neuroinflammation Induced P53, C-myc, Hsp70 Gene Over-expression. ( Principal Investigator(PI))
  15. 2015 - 2016, Geran Penyelidikan Universiti Malaya (UMRG) - AFR (Frontier Science)
    Effect of Preoperative Curcumin in Breast Cancer Patients ( Co-Researcher)
  16. 2011 - 2014, Geran Penyelidikan Universiti Malaya (UMRG) - HTM (Wellness)
    DEVELOPMENT OF HAMIN TOPICAL LOCAL ANAESTHIC SYSTEM FOR VENEPUNCTURE ( Principal Investigator(PI))
  17. 2009 - 2011, Geran Penyelidikan Universiti Malaya (UMRG)
    DEVELOPMENT OF SUPPOSITORY BASE FOR THE TRANSDERMAL DELEVERY OF INSULIN ( Principal Investigator(PI))
  18. 2008 - 2010, RU Geran
    PHARMACOKINETIC STUDY OF A NOVEL TETRAHYDROBIOPTERIN ANALOGUE, WSG 1002 ( Principal Investigator(PI))
  19. 2010 - 2010, 6
    BIOEQUIVALENCE LABORATARY ( Principal Investigator(PI))
  20. 2007 - 2009, RU Geran
    PHARMACOKINETIC ASSESSMENT OF TESTOSTERONE TRANSDERMAL DELIVERY SYSTEM USING SALIVA AS COMPARED TO PLASMA ( Principal Investigator(PI))
  21. 2017 - 2018, Private Funding
    Development of NIO-HAMIN Topical Local Anaesthetic System using Noisome Encapsulated Lidocaine and Mepivacaine with Hamin for Minor Surgery Application ( Principal Investigator(PI))
  22. 2014 - 2017, ScienceFund
    Preclinical Studies and standardisation of rhizophora mucronata and Mallotus muticus for Testosterone Replacement Therapy as prerequisite requirements for clinical Study ( Consultant)
  23. 2014 - 2016, Fundamental Research Grant Scheme (FRGS)
    Development of Targeted Biodegradable Nanoparticles for the Treatment of Cancer Metastasis ( Principal Investigator(PI))
  24. 2011 - 2015, High Impact Research (HIR)
    Analysis of Endocrine Disrupting Chemicals in Food and Environment Food and Environment ( Consultant)
  25. 2011 - 2014, Geran Penyelidikan Universiti Malaya (UMRG)
    Identification of Predictors for Dosing Determination of Metformin in Obese Children/Adolescents ( Consultant)
  26. 2012 - 2014, Geran Penyelidikan Universiti Malaya (UMRG)
    Developement of HAMIN topical local anaesthetic system for venepuncture ( Principal Investigator(PI))
  27. 2012 - 2014, ScienceFund
    Assessment of Appetite Suppressant Activities and Lipid Digestion Metabolite from Piper Betle Leaf Extracts Using Metabolomic Approach ( Consultant)
  28. 2012 - 2013, Geran Penyelidikan Universiti Malaya (UMRG)
    Determination of the effective route of administration of bioflavonoids as anti dengue virus agents in animal model ( Consultant)
  29. 2012 - 2012, PEMANDU, Prime Minister Department
    Gamma tocotrienol as potential maintenance treatment in woman with metastatic breast cancer treatment in woman with metastatic breast cancer ( Consultant)
  30. 2009 - 2011, Geran Penyelidikan Universiti Malaya (UMRG)
    Development of Suppository Base For The Transdermal Delivery of Insulin ( Principal Investigator(PI))
  31. 2008 - 2010, Short Term Research Fund (Vote F)(PJP)
    Salivary compared to systemic measurement in the pharmacokinetic assessment of testosterone transdermal delivery system for the hormone replacement therapy. ( Principal Investigator(PI))
  32. 2008 - 2010, Short Term Research Fund (Vote F)(PJP)
    Pharmacokinetic-pharmacodynamic-pharmacogenetic study of clozapine ( Consultant)
  33. 2008 - 2010, Geran Penyelidikan Universiti Malaya (UMRG)
    FACTORS AFFECTING ADHERENCE TO ANTIRETROVIRAL TREATMENT IN SUNGAI BULUH HOSPITAL ( Consultant)
  34. 2008 - 2009, Short Term Research Fund (Vote F)(PJP)
    Pharmacokinetic study of a novel tetrahydrobiopterin analogue, WSG 1002 ( Principal Investigator(PI))
Private
  1. 2010 - 2015, Private Funding
    BIOEQUIVALENCE LABORATORY ( Principal Investigator(PI))
University
  1. 2019 - 2022, Private Funding
    Phase Ii Randomized Controlled Trial Tiger Milk Mushroom (tm02) In Patients With Breast Cancer ( Co-Researcher)
  2. 2019 - 2022, Private Funding
    Development Of An Immunochemistry-based Assay For Detection And Quantitation Of Cobra Venom Antigens In Envenomation ( Co-Researcher)
  3. 2018 - 2021, Private Funding
    Venom Proteomics And Antivenom Immunological Study For Craspedocephalus Wiroti, A Medically Important Venomous Pit Viper In Malaysia ( Co-Researcher)
  4. 2017 - 2019, Private Funding
    A Prospective Study Of Meropenem And Piperacillin-tazabactam Penetration Into The Lungs In Hospital Acquired Pneumonia In Intensive Care Unit ( Co-Researcher)

CONSULTANCY PROJECT


  • The Development of Niosome-Encapsulated Nitric Oxide Nasal Spray for Covid 19 Infection Treatment, Initiative Asia Sdn. Bhd., Consultant
    20 Sep 2021 - 31 Jan 2022 (National)
  • Independent Reviewer for The Clinical Trials, Medika Natura Sdn Bhd, Project Leader/Lead Consultant
    15 Mar 2021 - 31 Dec 2021 (National)
  • Panel Penilai Harta Intelek Bertajuk Uhplc Method Development for Purity Analysis of Anticoagulant Rivaroxaban in Pharmaceutical Dosage Form, Universiti Sains Islam Malaysia
    01 Dec 2020 - 31 Jan 2021 (National)
  • Proposal to Review The Inspection Fee for Foreign Bioequivalence Inspection, NPRA, Ministry of Health
    01 Dec 2020 - 01 Dec 2020 (National)
  • Panel of Expert First in Human Studies, NPRA MInistry of Health
    01 Dec 2020 - 01 Dec 2020 (National)
  • Bioavailabilty Study of Two Formulations of Tocotrienol in Rats, Monash University
    01 Dec 2018 - 01 Dec 2019 (National)
  • Bioavailability Study of Granola Bar Fortified With Palm Trf, MPOB
    01 Dec 2018 - 01 Dec 2019 (National)
  • Comparative Evaluation of Relative Bioavailabilities of Two Formulations of Diclofenac Sodium 5omg Tablets in Healthy Adult Human Subjects Under Fasting Conditions, Chulia Pharma
    01 Dec 2018 - 01 Dec 2019 (National)
  • Bioavailability Study of Palm Chewable Tablets, Malaysian Palm Oil Berhad (MPOB)
    01 Dec 2018 - 01 Dec 2019 (National)
  • An Open Label, Randomized, Two Period, Two Sequence, Crossover, Comparative Evaluation of Relative Bioavailabilities of Two Formulations of Lorazepam 250mg Capsules, in Healthy Adult Human Subjects Under Fasting Conditions, Komedic Sdn. Bhd.
    01 Dec 2016 - 01 Dec 2017 (National)
  • An Open Label, Randomized, Two Period, Two Sequence, Crossover, Comparative Evaluation of Relative Bioavailabilities of Two Formulations of Bromazepam 3mg Capsules, in Healthy Adult Human Subjects Under Fasting Conditions, Komedic Sdn. Bhd.
    01 Jun 2014 - 01 Jun 2015 (National)
  • An Open Label, Randomized, Two Period, Two Sequence, Crossover, Comparative Evaluation of Relative Bioavailabilities of Two Formulations of Sulfamethoxazole 800mg + Trimethoprim 160mg, in Healthy Adult Human Subjects Under Fasting Conditions, Komedic Sdn. Bhd.
    01 Jun 2014 - 01 Jun 2014 (National)
  • An Open Label, Randomized, Two Period, Two Sequence, Crossover, Comparative Evaluation of Relative Bioavailabilities of Two Tablets Containing Atenolol 100mg and Chlorthalidone 25mg in Healthy Adult Human Subjects Under Fasting Conditions., Zyfas Medical Company
    01 Jun 2013 - 01 Jun 2014 (National)
  • Single Dose Bioequivalence Study of Captopril in 22 Healthy Subjects, Imeks Pharma Sdn. Bhd.
    01 Jun 2012 - 01 Jun 2013 (National)
  • The Comparative Bioequivalence Study of a Generic (Moridone Tablet 2 X 10 Mg Manufactured by Prime Pharmaceuticals) and The Proprietary (Motilium Tablet 2 X 10 Mg Manufactured by Janssen Cilag) 2 X 10 Mg Domperidone Tablets in Healthy Human Subjects., Prime Pharmaceutical
    01 Jun 2013 - 01 Jun 2013 (National)
  • Quantitation of Amlodipine (0.10 - 12ng/Ml) in Human Plasma Using Lc-Ms/Ms, IKOP Sdn Bhd. IIUM
    01 Jun 2012 - 01 Jun 2013 (National)
  • An Open Label, Randomized, Two Period, Two Sequence, Crossover, Comparative Evaluation of Relative Bioavailabilities of Two Formulations of Clopidogrel 5mg Tablets in Healthy Adult Human Subjects Under Fasting Conditions, Pharmaniaga
    01 Feb 2012 - 01 Feb 2013 (National)
  • Single Dose Bioequivalence Study of Captopril in 22 Healthy Subjects, Imeks Pharma Sdn Bhd.
    01 Jan 2012 - 01 Jan 2013 (National)
  • An Open Label, Randomized, Two Period, Two Sequence, Crossover, Comparative Evaluation of Relative Bioavailabilities of Two Formulations of Omeprazole 20mg Tablets in Healthy Adult Human Subjects Under Fasting Conditions, Prime Pharmaceutical
    01 Jun 2012 - 01 Jun 2012 (National)
  • An Open Label, Randomized, Two Period, Two Sequence, Crossover, Comparative Evaluation of Relative Bioavailabilities of Two Formulations of Tetracycline 250mg Tablets in Healthy Adult Human Subjects Under Fasting Conditions, Dynapharm Sdn. Bhd.
    01 Jun 2012 - 01 Jun 2012 (National)
  • An Open Label, Randomized, Two Period, Two Sequence, Crossover, Comparative Evaluation of Relative Bioavailabilities of Two Formulations of Omeprazole 20mg Tablets in Healthy Adult Human Subjects Under Fasting Conditions, PRIME PHARMACEUTICAL
    01 Apr 2012 - 01 Apr 2012 (National)
  • An Open Label, Randomized, Two Period, Two Sequence, Crossover, Comparative Evaluation of Relative Bioavailabilities of Two Formulations of Tetracycline 250mg Tablets in Healthy Adult Human Subjects Under Fasting Conditions, DYNAPHARM SDN. BHD.
    01 Apr 2012 - 01 Apr 2012 (National)
  • An Open Label, Randomized, Two Period, Two Sequence, Crossover, Comparative Evaluation of Relative Bioavailabilities of Two Formulations of Omeprazole 20mg Tablets in Healthy Adult Human Subjects Under Fasting Conditions, PRIME PHARMACEUTICAL
    01 Apr 2012 - 01 Apr 2012 (National)
  • Analysis of Dehp in Food Samples, Ministry of Health Malaysia
    01 Feb 2011 - 01 Feb 2012 (National)
  • Analysis of Captopril in Human Plasma by Lcmsms, USAINS Holding
    01 Feb 2012 - 01 Feb 2012 (National)
  • An Open Label, Randomized, Two Period, Two Sequence, Crossover, Comparative Evaluation of Relative Bioavailabilities of Two Formulations of Diazepam 5mg Tablets in Healthy Adult Human Subjects Under Fasting Conditions, Idaman Pharma Manufacturing Sdn Bhd.
    01 Feb 2011 - 01 Feb 2012 (National)
  • An Open Label, Randomized, Two Period, Two Sequence, Crossover, Comparative Evaluation of Relative Bioavailabilities of Two Formulations of Griseofulvin 500mg Tablet in Healthy Adult Human Subjects Under Non-Fasting Conditions., Idaman Pharma Manufacturing Sdn Bhd.
    01 Aug 2010 - 01 Aug 2011 (National)
  • An Open Label, Randomized, Three Period, Six Sequence, Crossover, Comparative Evaluation of Relative Bioavailabilities of Three Formulations of Ampicillin 250mg Capsules in Healthy Adult Subjects Under Fasting Conditions, Idaman Pharma Manufacturing Sdn Bhd.
    01 Aug 2010 - 01 Aug 2011 (National)
  • An Open Label, Randomized, Three Period, Six Sequence, Crossover, Comparative Evaluation of Relative Bioavailabilities of Three Formulations of Cloxacillin 250mg Tablet in Healthy Adult Subjects Under Fasting Conditions, Idaman Pharma Manufacturing Sdn Bhd.
    01 Aug 2010 - 01 Aug 2011 (National)
  • An Open Label, Randomized, Three Period, Six Sequence, Crossover, Comparative Evaluation of Relative Bioavailabilities of Three Formulations of Amoxicillin Capsules 250mg in Healthy Adult, Idaman Pharma Manufacturing Sdn Bhd.
    01 Feb 2010 - 01 Feb 2011 (National)
  • An Open Label, Randomized, Two Period, Two Sequence, Crossover, Comparative Bioavailabilities of Two Formulations of Tetracycline 250mg Capsules in Healthy Adult Human Subjects Under Fasting Conditions, Idaman Pharma Manufacturing Sdn Bhd.
    01 Feb 2011 - 01 Feb 2011 (National)
  • An Open Label, Randomized, Two Period, Two Sequence, Crossover, Comparative Evaluation of Relative Bioavailabilities of Two Formulations of Naproxen 550mg Tablets in Healthy Adult Human Subjects Under Fasting Conditions, Dynapharm (M) Sdn. Bhd.
    01 Feb 2009 - 01 Feb 2010 (National)
  • Analysis of Melamine in Food Samples, Kementerian Kesihatan Malaysia
    01 Feb 2008 - 01 Feb 2009 (National)
  • An Open Label, Randomized, Two Period, Two Sequence, Crossover, Comparative Evaluation of Relative Bioavailabilities of Two Formulations of Cetirizine 10mg Tablets in Healthy Adult Human Subjects Under Fasting Conditions, SM Pharmaceutical Sdn Bhd
    01 Feb 2008 - 01 Feb 2008 (National)
  • An Open-Label, Randomized, Two-Period, Two Sequence, Crossover, Comparative Evaluation of Relative Bioavailabilities of Two Formulations of Rifampicin 300mg in Healthy Adult Male Subjects Under Fasting Conditions ., Idaman Pharma Manufacturing Sdn. Bhd.
    01 Feb 2007 - 01 Feb 2008 (National)
  • An Open Label, Randomized, Two Period, Two Sequence, Crossover, Comparative Evaluation of Relative Bioavailabilities of Two Formulations of Terbutaline 2.5mg Tablet in Healthy Adult Human Subjects Under Fasting Conditions, Idaman Pharma Manufacturing Sdn.Bhd.
    01 Feb 2008 - 01 Feb 2008 (National)
  • An Open Label, Randomized, Two Period, Two Sequence, Crossover, Comparative Evaluation of Relative Bioavailabilities of Two Formulations of Ketoconazole 200mg Tablet in Healthy Adult Human Subjects Under Fasting Conditions, SM Pharmaceuticals Sdn. Bhd.
    01 Feb 2008 - 01 Feb 2008 (National)
  • An Open Label, Randomized, Two Period, Two Sequence, Crossover, Comparative Evaluation of Relative Bioavailabilities of Two Formulations of Ibuprofen 400mg Tablets in Healthy Adult Human Subjects Under Fasting Conditions, SM Pharmaceutical Sdn Bhd
    01 Feb 2008 - 01 Feb 2008 (National)
  • An Open-Label, Randomised, Two-Period, Two Sequence, Crossover, Comparative Evaluation of Relative Bioavailabilities of Two Formulations of Doxycycline in Healthy Adult Male Subjects Under Fasting Conditions., Innovax Sdn. Bhd.
    01 Feb 2007 - 01 Feb 2007 (National)

PAPER PRESENTED


ORAL PRESENTER
  1. The Chemotherapeutic Efficacy of Hyaluronic Acid Coated Polymeric Nanoparticles Against breast Cancer Metastasis: In Vivo Study, International Conference on Pharmaceutics and Drug Delivery 2022, Coalesce Research Group (International) (14 Nov 2022 - 15 Nov 2022)
  2. The effect of Piper betle leave extracts on weight, food intake and behaviour of SD Rats by using Elevated Plus-Maze (EPM), 5th International Mediterranean Symposium on Medicinal and Aromatic Plants & 5th International Symposium on Pharmaceutical and Biomedical Sciences April, 24-28, 2019 / Cappadocia - TURKEY, MESMAP & ISPBS (International) (24 Apr 2019 - 28 Apr 2019)
  3. Effect of Cytochrome P450 (CYP2D6) Inhibition in In Vivo toxicity Studies of Mitragyna, International Conference on Toxicology and Clinical Pharmacology, Allied Academies (International) (14 Dec 2017 - 16 Dec 2017)
  4. Pharmacokinetics and bioavailability of Mitragynine in Sprague Dawley (SD) Rats using microdialysis, APSA 2016 Annual Conference, Australasian Pharmaceutical Science Association (International) (01 Dec 2016 - 05 Dec 2016)
  5. Physical and Chemical Characteristics of a novel Hamin Insulin Suppositories , 27th Scientific Meeting Malaysian Society of Pharmacology and Physiology , International Islamic University of Malaysia (International) (06 Sep 2013 - 08 Sep 2013)
  6. Umar Y Mohammed, Awang M Bulgiba, Zamri B chik, Christopher Lee, Devi Peramalah (2012). Is Therapeutic Drug Monitoring (TDM) the best method for measuring adherence level to HAART in HIV positive patients in Kuala Lumpur Malaysia? , APACPH 2012  (International) (22 Mar 2012 - 25 Mar 2012)
  7. Comparative pharmacokinetic assessments of topically applied drugs: Evaluation by dermatopharmacokinetics, microdialysis and systemic measurement., British Pharmacological Society Winter Meeting, British Pharmacological Society (International) (21 Dec 2006 - 22 Dec 2006)
  8. Bioequivalence study of two tablet formulations of captopril (Brand B vs. Brand leader) in healthy volunteers, 15th Scientific Meeting of the Malaysian Society of Pharmacology and Physiology(MSPP), Malaysian Society of Pharmacology and Physiology(MSPP) (National) (16 May 2000 - 17 May 2000)
  9. Bioequivalence study of two tablet formulations of captopril (Brand A vs. Brand leader) in healthy volunteers, Annual Scientific Sessions, National Heart Association of Malaysia, National Heart Association of Malaysia (National) (08 Feb 2000 - 09 Feb 2000)
POSTER PRESENTER
  1. Khat (Catha edulis) Exacerbate Insulin Resistance in A High-Fat Diet/Streptozotocin-Induced Rat Model of Type 2 Diabetes Mellitus, 18th Annual World Congress on Insulin Resistance Diabetes & Cardiovascular Disease, The Metabolic Institute of America (International) (03 Dec 2020 - 06 Dec 2020)
  2. Preparation of Targeted PEG-PLGA Nanoparticles For The Treatment of Cancer Metastasis, World Congress of Clinical Pharmacology, IUPHAR (International) (01 Jul 2018 - 06 Jul 2018)
  3. Development of HaminTM Testosterone Transdermal Delivery System and its in vitro and in vivo evaluations, 19th North AmericanISSX/ 29th JSSX Meeting , International Society of Xenobiotics (International) (19 Oct 2014 - 23 Oct 2014)
  4. Development of a novel HAMIN topical local anaesthetic system for venepuncture. Zamri Chik, Sitti Norkhamdiah and Ibrahim Noordin, Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) Annual Scientific Meeting. , ASCEPT (International) (01 Dec 2013 - 04 Dec 2013)
  5. AN EVALUATION OF PARACETAMOL PROTEIN ADDUCTS IN MALAYSIAN PATIENTS WITH ACETAMINOPHEN OVERDOSE, ASCEPT. AUPS, HBPRCA JOINT MEETING, ASCEPT AUSTRALIA (International) (03 Dec 2011 - 09 Dec 2011)
  6. Analysis of melamine in various food products marketed in Malaysia" has been accepted for poster presentation at the 4th . The meeting will take place in Tainan, Taiwan April 22 - 25, 2011, Asia Pacific Regional ISSX Meeting, ISSX (International) (22 Apr 2011 - 25 Apr 2011)
  7. Analysis of melamine in various food products marketed in Malaysia, 4t Asian Pacific Regional Meeting of ISSX, National Cheng Kung University (International) (22 Apr 2011 - 25 Apr 2011)
  8. Analysis of Melamine in Food contact articles available in Malaysian market, 16th World Congress of basic and clinical phramacology, Danish Society for Pharmacology (International) (17 Jul 2010 - 23 Jul 2010)
  9. Melamine migration from melamine food contact articles available on the Malaysian market, 16th World Congress of Basic and Clinical Pharmacology , Danish Society of Pharmacology and British Pharmacological Society (International) (17 Jul 2010 - 23 Jul 2010)
  10. Bioequivalence study of two tablet formulations of Rifampicin in healthy adult subjects., 33rd Annual Conference of the Malaysian Society For Biochemistry and Molecular Biology, Kuala Lumpur, Malaysia Society of Biochemistry and Molecular Biology (27 Aug 2008 - 28 Aug 2008)
  11. Bioequivalence study of two tablet formulations of salbutamol in healthy adult subjects., 22nd MSPP Scientific Meeting, Kuala Lumpur April 2008, Malaysia Society of Pharmacology and Physiology (05 Apr 2008 - 06 Apr 2008)
  12. Population analysis of pharmacokinetic parameters of captopril in healthy adult Malaysian subjects, 10th SEAWP and 41st ASCEPT Joint Meeting, Adelaide, South Australia., 1)South Asian Western Pacific Regional Meeting of Pharmacologists (SEAWP-RMP) 2) Australasian Society of Clinical and Experimental Pharmacologists abd Toxicologists  (International) (02 Dec 2007 - 06 Dec 2007)
  13. A New Testosterone Transdermal Delivery System, TDS -testosterone, Has Superior Pharmacokinetics Compared to an Existing Transdermal Preparation in Healthy Males., Proceedings of the ENDO 2006, The Endocrine Society s 88th Annual Meeting, Boston, Massachusetts, USA, The Endocrine Society (International) (24 Jun 2006 - 27 Jun 2006)
  14. The influence of correcting endogenous concentrations in the bioequivalence assessment of testosterone, British Pharmacological Society(BPS) Winter Meeting, British Pharmacological Society (19 Dec 2005 - 21 Dec 2005)
  15. Study of a combined percutaneous local anaesthetic and the TDS system for venepuncture, 2nd EUFEPS Conference on Optimising Drug Delivery and Formulation, The European Federation for Pharmaceutical Sciences (International) (17 Nov 2005 - 20 Nov 2005)
  16. Pharmacokinetic of the new testosterone transdermal delivery system, TDS -Testosterone in healthy subjects, British Pharmacological Society(BPS) Winter Meeting, . December 2004., British Pharmacological Society (International) (14 Dec 2004 - 16 Dec 2004)
  17. Pharmacokinetic of two doses of oral captopril in healthy subjects, 16th Scientific Meeting of the Malaysian Society of Pharmacology and Physiology(MSPP), Malaysian Society of Pharmacology and Physiology(MSPP) (National) (25 Jun 2001 - 26 Jun 2001)

ACADEMIC/PROF. SERVICES


Evaluation
  1. (2024) Panel Penilai Di Bawah Jawatankuasa Unit Pemantapan Kertas Cadangan Penyelidikan, University, (Reviewer)
  2. (2024) External Examiner for Segi University, National, (External Assessor)
  3. (2024) External Examiner for MBBS Professional Examination for UPM, National, (External Examiner)
  4. (2024) External Examiner for MBBS Program UPM, National, (External Assessor)
  5. (2023) Panel of Assessor for UM Research Excellent Grant (Umreg), University, (Internal Assessor)
  6. (2023) Chairperson for Phd Candidature Defense Malarmugila Manimaran, University, (Internal Examiner)
  7. (2023) External Examiner for MBBS Program Segi University, National, (External Assessor)
  8. (2023) Penilai Proposal Geran Frgs Peringkat Kementerian Pengajian Tinggi, National, (Reviewer)
  9. (2023) Examiner for Phd Candidature Defense Tanusha M Ganesan, University, (Internal Examiner)
  10. (2023) Chairperson of Master Proposal Defense Yap Yi Jing, University, (Internal Examiner)
  11. (2023) Chairperson for Phd Proposal Defense Khor Yi Sheng, University, (Internal Examiner)
  12. (2023) Penilai Proposal Permohonan Frgs Peringkat Universiti Malaya, University, (Reviewer)
  13. (2023) External Examiner for MBBS Program UPM, National, (External Assessor)
  14. (2023) External Examiner for MBBS Program UPM, National, (External Assessor)
  15. (2023) External Examiner for Phd Confirmation Defense Teh Hue Xhin_ Dept of Biomedical Science, University, (External Examiner)
  16. (2023) Chairperson for Phd Proposal Defense Goh Zher Pin, University, (Internal Examiner)
  17. (2023) Chairperson for The Phd Proposal Defense Goh Sook Jing, University, (Internal Examiner)
  18. (2022) Chairperson for Candidature Defense_siti Zaleha Suki, University, (Internal Evaluator)
  19. (2022) Proposal Defense for Master of Medical Science Student-Malarmugila Manimaran, University, (Internal Evaluator)
  20. (2022) Chairperson for Phd Candidature Defense Siti Zaleha, University, (Reviewer)
  21. (2022) Research Proposal for Phd, University, (Reviewer)
  22. (2022) Chairperson for Researh Proposal for Phd Application, University, (Reviewer)
  23. (2022) Penilai for Proposal Defense of Master of Medical Sc (Tien Xien Yi), University, (Reviewer)
  24. (2022) Penemuduga Bagi Program MBBS Ambilan Sessi 2022/23, University, (Internal Evaluator)
  25. (2022) Research Proposal Evaluation for Phd, University, (Reviewer)
  26. (2022) Research Proposal Evaluator for Phd Application, University, (Reviewer)
  27. (2022) Research Grant Proposal Evaluation Panel, University, (Reviewer)
  28. (2022) Chairperson for The Research Proposal for Phd Application, University, (Reviewer)
  29. (2022) Panel Penilai Permohonan Geran Frgs Peringkat Universiti Malaya, University, (Reviewer)
  30. (2022) Panel Penilai Dana Penyelidikan Kementerian Pengajian Tinggi, National, (External Assessor)
  31. (2022) Panel of Expert First-in-Human Trial, National, (External Assessor)
  32. (2022) Panel of Expert Kajian Klinikal First-in-Human, National, (External Assessor)
  33. (2021) External Examiner of Phd Thesis, International, (External Examiner)
  34. (2021) Reviewer for The Article Title: Dermatopharmacokinetics to Determine Application Time of Emla Cream in Pediatric Patients, International, (Reviewer)
  35. (2021) Panel Penilai Skim Grant Fundamental Fasa 1 2021, University, (Internal Evaluator)
  36. (2021) Jawatankuasa Penilaian Permohonan Malaysia-France Bilateral Research Collaboration 2021 (Match), National, (External Evaluator)
  37. (2021) Panel Penilai Dana Kementerian Pengajian Tinggi, National, (External Evaluator)
  38. (2020) Assessor for Proposal Defense Department of Medicine of PhD canditate, (External Examiner)
  39. (2020) Panel Penilai Harta Intelek Universiti Sains Islam Malaysia, (Reviewer)
  40. (2020) Assessor for Proposal Defense Department of Medicine of PhD canditate , (External Examiner)
  41. (2020) Appointed by NPRA to be panel of Expert for First in Human Study of Drug Trial , (Advisory Committee)
  42. (2020) Reviewer for UMSC CARE Fund Application, (Reviewer)
  43. (2020) Reviewer for the Inspection Fees for Foreign Bioequivalence Studies, (Reviewer)
  44. (2016) Reviewer for the following article submitted to the Journal of Chromatographic Sc. "A Review on HPLC-UV Methods for the Analysis of Gliptins in Pharmaceutical Dosage Forms", (Reviewer)
  45. (2016) Design and development of Nano cosmeceutical skin care containing collagen from local jellyfish, (Evaluation committee for HLAF Scholarship)
  46. (2015) Reviewer for a Biomedical Chromatography Journal: A High Throughput Method for Determination of Captopril in Human Plasma by Liquid Chromatography/ Tandum Mass Spectrometry. Application to a Bioequivalence Study , (Reviewer)
  47. (2015) Development of fast detection method for adulterants by using thermal analysis. Maria Binti Jaafar Master of Medical Science, (Internal Examiner)
  48. (2015) Modelling and Simulation Approach towards effective use of antiepileptic drugs in patients with epilepsy. Yeap Li Ling, Candidature Defense for PhD, (Internal Examiner)
  49. (2014) Separation and determination of the tricyclic derivatives of pyrazolo[4,3-e][1,2,4]- triazine using high performance liquidchromatography, (Reviewer)
  50. (2014) Internal examiner for MMedSci candidature defense for Nurul Dhania Zaharuddin, (Internal Examiner)
  51. (2013) Application of a liquid chromatography tandem mass spectrometry method to the pharmacokinetics, tissue distribution and excretion studies of ginkgolic acid (17:1) in rats, (Reviewer)
  52. (2013) Quantitative Determination of Indole-3-acetonitrile-6-O-β-D-glucopyranoside in Rat Plasma by Liquid Chromatography-Mass Spectrometry, (Reviewer)
  53. (2012) Determination and Pharmacokinetic study of Voriconazole in Human Plasma by HPLC-ESI-MS and its Application to Pharmacokinetic Study, (Reviewer)
  54. (2010) Determination of Estrogen and Phytoestrogen residues in milk product from Malaysia and Saudi Arabia. Anas Abulela, Master of Medical Science, (Internal Examiner)
Contribution to external organisation
  1. (2024) Ahli Jawatankuasa Penyelidikan Klinikal Kebangsaan, National, (Resource Person)
  2. (2024) Appointment for Technical Assessor for Samm, National, (Technical Advisor)
  3. (2024) Pelantikan Panel of Expert (Poe) Bagi Kajian Klinikal First in Human (Fih), National, (Expert Advisor)
  4. (2022) Ahli Jawatankuasa Tabung Umsc Care, University, (Academic Appointment )
  5. (2022) Ahli Jawatankuasa Penyelidikan Klinikal Kebangsaan, National, (Expert Advisor)
  6. (2022) Ahli Jawatankuasa Penyelidikan Klinikal Kebangsaan, National, (Academic Appointment )
  7. (2021) Panel of Expert for First in Human Trial, National, (Expert Advisor)
  8. (2020) Ahli Jawatankuasa Penilai Dana Penyelidikan Kementerian Pengajian Tinggi, Kementerian Pengajian Tinggi
  9. (2020) Member of Reviewer Board of the Deanship of Research jazan University, KSA, University of Jazan, KSA
  10. (2019) Subspecialty Training/ Join Study Agreement , IBM California USA, International
  11. (2017) External Examiner for PhD thesis, University of Southern Queensland Australia
  12. (2016) Research Collaboration, Cancer Research Malaysia, National
  13. (2014) Memorandom of Agreement. Co Investigator for project: Preclinical Studies and standardisation of rhizophora mucronata and Mallotus muticus for Testosterone Replacement Therapy as prerequisite requirements for clinical Study, SIRIM-UM, National
  14. (2014) Ahli jawatankuasa penilaian teknikal dan spesifikasi perolehan bekalan melebihi RM200,000, University Malaya
  15. (2011) Module moderator for Foodb Safety and Health, Open University Malaysia, National
  16. (2009) Food additive expert, Ministry of Health, University
  17. (2009) Laboratory Accreditation for ISO 17025, University Malaya Bioequivalece Testing Centre (UBAT) and Shimadzu UMMC Centre for Xenobiotics Studies (SUCXeS)
  18. (2008) Analysis of melamine in foods, Ministry of Health Malaysia
Contribution to event
  1. (2022) Oral Presentation, International, (Participant)
Media appearance
  1. (2023) Pelantikan Sebagai Penceramah/Moderator Bagi Webinar Biomedical Research Fakulti Perubatan dan National Yang Ming Chiou Tung University Taiwan, International, (Panelist/Moderator)

SUPERVISION


Under Graduate Students
  1. (2021) DEvelopement of LCMSMS method for the analysis of lidocaine in human plasma
  2. (2010) Non-invasive transdermal insulin delivery in Rabbits
  3. (2010) Development of LCMSMS method for the analysis of Metformin in Plasma
  4. (2009) To assess patient's compliance to the inhalation technique in Obstrutive Lung Disease
  5. (2008) Development of HPLC method to measure insulin in human plasma
Postgraduate Student
PhD/ Doctoral
  1. (2023) UNUSED MEDICINES: PREVALENCE, DISPOSAL PRACTICES, ASSOCIATED FACTORS AND GUIDELINES, WANG LEONG SENG
  2. (2023) IMMUNOMODULATORY EFFECTS OF NATURAL COMPOUNDS IN BREAST CANCER, PUVANESWARI A/P MEGANATHAN
  3. (2023) INVESTIGATING THE ROLE OF MIRNA AND EXOSOMES IN MODULATING CYTOSKELETON AND ECM CHANGES IN PSORIATIC SKIN, LI, SIJING
  4. (2023) Poly-L-glutamic Acid as Targeted Drug Carrier of 4-(2 aminoethyl) benzenesulfonyl fluoride (AEBSF) for Prevention or Attenuation of Acute Kidney Injury – An In Vivo Mechanistic Study, HUI NEE GEO
  5. (2023) ANTIBIOTIC OPTIMIZATION IN THE CRITICALLY III PATIENT, HELMI BIN SULAIMAN
  6. (2022) DESIGN AND DEVELOPMENT OF PLGA PEGYLATED NANOPARTICLE CONJUGATED WITH A6 PEPTIDE LOADED WITH DOXORUBICIN AND ANTI-MIR 21 FOR TARGETED ENHANCED INHIBITION OF TRIPLENEGATIVE BREAST CANCER, Zaidah Binti Ibrahim (Taylor's University)
  7. (2022) Design and Preparation of Polymeric Nanoparticles/Gels from the Transdermal Delivery of Testosterone., HIRA FATIMA ABBAS
  8. (2021) TARGETED POLYMERIC NANOPARTICLE FORMULATION FOR THE TREATMENT OF BREAST CANCER METASTASIS, HASSAN ALMOUSTAFA
  9. (2020) Lipopolysaccharide (LPS) preconditioning inhibits pro-inflammatory and proto-oncogenes responses and promotes cytoprotective effect in differentiated PC12 cell lines., PUSHPA GANDI SANGARAN
  10. (2020) IMMUNOMODULATORY EFFECTS OF NATURAL COMPOUNDS IN BREAST CANCER, PUVANESWARI A/P MEGANATHAN
  11. (2020) Genotoxicity, Teratogenicity and Postnatal Developmental Toxocity Studies of Verbena Officinalis and Capsella Bursa-Pastoris as Traditional Herbals., Abdul Mannan Hassan Saad
  12. (2020) ANTIBIOTIC OPTIMIZATION IN THE CRITICALLY III PATIENT, HELMI BIN SULAIMAN
  13. (2020) Lipopolysaccharide (LPS) preconditioning inhibits pro-inflammatory and proto-oncogenes responses and promotes cytoprotective effect in differentiated PC12 cell lines., PUSHPA GANDI SANGARAN
  14. (2019) Mutagenicity, Genotoxicity and Prenatal Developmental Toxicity Studies of Verbena officinalis, ABDULMANNAN HASAN SAAD AL-DUBAI
  15. (2019) Design and Preparation of Polymeric Nanoparticles/Gels from the Transdermal Delivery of Testosterone., HIRA FATIMA ABBAS
  16. (2019) Mutagenicity, Genotoxicity and Prenatal Developmental Toxicity Studies of Verbena officinalis, ABDULMANNAN HASAN SAAD AL-DUBAI
  17. (2018) STUDIES ON WEIGHT REDUCTION PROPERTIES OF PIPER BETLE L. LEAF EXTRACT USING ELEVATED PLUS MAZE AND 1H NMR-BASED METABOLOMIC APPROACH, ZULEEN DELINA FASYA BINTI ABDUL GHANI
  18. (2018) PHYTOCHEMICAL SCREENING AND EVALUATION OF REPRODUCTIVE ACTIVITIES OF ASPARAGUS AFRICANUS LAM ROOT EXTRACT IN SPRAGUE-DAWLEY RATS, ABUBAKAR EL-ISHAQ
  19. (2018) Investigation into The Glycemic Properties of Catha edulis (Khat) Extract in Diabetic-Induced Sprague-Dawley Rats, ABDUL SAMAD AHMED MOKBEL AL-SALAHI
  20. (2018) Investigation into The Glycemic Properties of Catcha Edulis (Khat) Ethanolic Extract: Meta-Analysis and Preclinical Studies, ABDUL SAMAD AHMED MOKBEL AL-SALAHI
  21. (2018) IMMUNOMODULATORY EFFECTS OF NATURAL COMPOUNDS IN BREAST CANCER, PUVANESWARI A/P MEGANATHAN
  22. (2018) Effect of Lipopolysaccharide preconditioning inhibits pro-inflammatory and proto-oncogenes responses and promotes cytoprotective effect in differentiated PC12 cell lines., PUSHPA GANDI A/P SANGARAN
  23. (2018) DEVELOPMENT OF A MULTISCALE MECHANISTIC MODEL FOR TARGETED NANOPARTICLES IN THE TREATMENT CANCER METASTASIS, HASSAN ALMOUSTAFA
  24. (2018) Design and Preparation of Polymeric Nanoparticles/Gels from the Transdermal Delivery of Testosterone., HIRA FATIMA ABBAS
  25. (2018) ANTIBIOTIC OPTIMIZATION IN THE CRITICALLY III PATIENT, HELMI BIN SULAIMAN
  26. (2018) PHYTOCHEMICAL SCREENING AND EVALUATION OF REPRODUCTIVE ACTIVITIES OF ASPARAGUS AFRICANUS LAM ROOT EXTRACT IN SPRAGUE-DAWLEY RATS, ABUBAKAR EL-ISHAQ
  27. (2018) STUDIES ON WEIGHT REDUCTION PROPERTIES OF PIPER BETLE L. LEAF EXTRACT USING ELEVATED PLUS MAZE AND 1H NMR-BASED METABOLOMIC APPROACH, ZULEEN DELINA FASYA BINTI ABDUL GHANI
  28. (2018) Investigation into The Glycemic Activity of Ethanolic Catcha Edulis (Khat) Extract : Systematic Review, Meta-Analysis and Preclinical Studies, ABDUL SAMAD AHMED MOKBEL AL-SALAHI
  29. (2017) Preconditioning Prevent Neuroinflammation Induced P53, C-myc, Hsp70 Gene Over-expression., Pushpa Gandhi
  30. (2017) PRE-CLINICAL PHARMACOKINETICS AND TOXICOLOGICAL STUDIES OF MITRAGYNA SPECIOSA ALKALOID EXTRACT AND ITS ACTIVE COMPOUND, MITRAGYNINE, KONG WAI MUN
  31. (2017) Mechanisms of the Anti-tumor Activity of Methyl 2-(5-fluoro-2-hydroxyphenyl)-1H- Benzo[d]imidazole-5- carboxylate (MBIC) Against Breast Cancer in Vitro and in Vivo., MOHADESEH HASANPOURGHADI
  32. (2017) Mechanisms of the Anti-tumor Activity of Methyl 2-(5-fluoro-2-hydroxyphenyl)-1H- Benzo[d]imidazole-5- carboxylate (MBIC) Against Breast Cancer in Vitro and in Vivo., MOHADESEH HASANPOURGHADI
  33. (2017) PRE-CLINICAL PHARMACOKINETICS AND TOXICOLOGICAL STUDIES OF MITRAGYNA SPECIOSA ALKALOID EXTRACT AND ITS ACTIVE COMPOUND, MITRAGYNINE, KONG WAI MUN
  34. (2016) Genotoxicity, Teratogenicity and Postnatal Developmental Toxocity Studies of Verbena Officinalis and Capsella Bursa-Pastoris as Traditional Herbals., ABDULMANNAN HASAN SAAD
  35. (2016) Elucidating The Mechanistic Action of Methyl 2-(5-Fluoro-3-Hydroxyphenyl)-1H-Benzo [d]imidazole-5-Carbonxylate as A Potential Antitumor Agent, MOHADESEH HASANPOURGHADI
  36. (2015) Xenobiotics and Breast Cancer Risk and Prognosis., HIRA FATIMA ABBAS
  37. (2014) Effect of Bioactive components of Asparagus Africanus L extracts on reproductive functions in rats, Abu Bakar ElIshaq
  38. (2014) Development of Targeted Biodegradable Nanoparticles for the Treatment of Cancer Metastasis, Hasan Al Moustafa
  39. (2012) Assessment of Appetite Suppressant Activities and Lipid Digestion Metabolite from P.betle leaf extracts using metabolomic approach, Zuleen Delina Fasya Binti Abdul Ghani
  40. (2011) ADHERENCE TO HIGHLY ACTIVE ANTI-RETROVIRAL TREATMENT (HAART) AND ITS ASSOCIATED FACTORS AMONG HIV-POSITIVE PATIENTS IN SUNGAI BULOH, MALAYSIA, UMAR YAGOUB MOHAMMED
  41. (2010) Prevalence of Hepatotoxicity & Evaluation of a biomarker in Malaysian adults with paracetamol overdose, Marzilawati binti Abd Rahman
  42. (2010) IN VITRO TOXICOLOGICAL STUDIES OF MITRAGYNA SPECIOSA, Kong Wai Mun
  43. (2008) FACTORS AFFECTING ADHERENCE TO ANTIRETROVIRAL TREATMENT IN HOSPITAL SUNGAI BULUH, Umar Yagoub
Master
  1. (2023) Development of Niosome Encapsulated Lidocaine and Prilocaine with Hamin® Base (Nio-Hamin) for Topical Local Anaesthetic Delivery, AIDAWATI BINTI MOHAMED SHABERY
  2. (2023) Immunomodulatory and Preventive Effects of Bacterial and Yeast Probiotics Against Colorectal Cancer in a Mouse Model, Wardah Alsalemi
  3. (2021) BIODISTRIBUTION & PHARMACOKINETICS OF TOCOTRIENOL FOR INTRAVENOUS ADMINISTRATION, WONG FU SHUN
  4. (2020) DEVELOPMENT OF NIO-HAMIN? TOPICAL LOCAL ANESTHETIC SYSTEM USING NIOSOME ENCAPSULATED LIDOCAINE AND MEPIVACAINE WITH HAMIN? FOR MINOR SURGERY APPLICATION, AIDAWATI BINTI MOHAMED SHABERY
  5. (2020) BIODISTRIBUTION & PHARMACOKINETICS OF TOCOTRIENOL FOR INTRAVENOUS ADMINISTRATION, WONG FU SHUN
  6. (2020) FORMULATION DESIGN AND OPTIIMIZATION OF ORODISPERSIBLE TABLETS OF VARDENAFIL HYDROCHLORIDE TRIHYDRATE BY SUBLIMATION METHOD, GAN KOK ZHENG
  7. (2019) PUNICALAGIN REGULATES APOPTOSIS-AUTOPHAGY SWITCH VIA MODULATION OF ANNEXIN A1 COLORECTAL CANCER LINES, THANUSHA M GANESAN
  8. (2018) FORMULATION DESIGN AND OPTIIMIZATION OF ORODISPERSIBLE TABLETS OF VARDENAFIL HYDROCHLORIDE TRIHYDRATE BY SUBLIMATION METHOD, GAN KOK ZHENG
  9. (2018) DEVELOPMENT OF NIO-HAMIN? TOPICAL LOCAL ANESTHETIC SYSTEM USING NIOSOME ENCAPSULATED LIDOCAINE AND MEPIVACAINE WITH HAMIN? FOR MINOR SURGERY APPLICATION, AIDAWATI BINTI MOHAMED SHABERY
  10. (2018) BIODISTRIBUTION & PHARMACOKINETICS OF TOCOTRIENOL FOR INTRAVENOUS ADMINISTRATION, WONG FU SHUN
  11. (2018) ANNEXIN A1 REGULATES THE ANTI-CANCER EFFECTS OF PUNICALAGIN IN COLORECTAL CANCER CELL LINES, THANUSHA M GANESAN
  12. (2018) -, LIM SIAU PENG
  13. (2016) Palm Oil Base formulation of a topical local anaesthetic system and its in vivo and in vitro evaluations, SITTI NOR KHAMDIAH BINTI KHODARI
  14. (2016) Palm Oil Base formulation of a topical local anaesthetic system and its in vivo and in vitro evaluations, SITTI NOR KHAMDIAH BINTI KHODARI
  15. (2015) PARABENS, BODY CARE COSMETICS, OESTROGENICITY AND BREAST CANCER, NOR SHAMEEM BINTI MOHAMED SHARIFF
  16. (2015) In Vitro and In Vivo evaluation of a novel palm oil based Insulin suppository, SRITHARAN NAIR A/L THAMBI NAIR
  17. (2015) THE ROLE OF GENETIC POLYMORPHISMS AND HLA VARIANTS ON CLINICAL OUTCOMES IN MALAYSIAN RENAL TRANSPLANT PATIENTS ON CALCINEURIN INHIBITORS, RHANYE MAC GUAD
  18. (2015) In Vitro and In Vivo evaluation of a novel palm oil based Insulin suppository, SRITHARAN NAIR A/L THAMBI NAIR
  19. (2015) PARABENS, BODY CARE COSMETICS, OESTROGENICITY AND BREAST CANCER, NOR SHAMEEM BINTI MOHAMED SHARIFF
  20. (2014) COMPARATIVE BIOAVAILABILITY STUDY OF TWO FORMULATIONS OF GAMMA DELTA TOCOTRIENOL IN HEALTHY HUMAN SUBJECTS, PUVANESWARI A/P MEGANATHAN
  21. (2014) Antiviral activity and bioavailability of the metabolites of baicalein and quercetin as anti-dengue virus agents, EHSAN MOGHADDAM
  22. (2014) Antiviral activity and bioavailability of the metabolites of baicalein and quercetin as anti-dengue virus agents, EHSAN MOGHADDAM
  23. (2013) Development of Testosterone semi solid Transdermal delivery system using palm oil base and its in vitro and in vivo evaluation, DIDI ERWANDI BIN MOHAMAD HARON
  24. (2013) Developement of HAMIN topical local anaesthetic system for venepuncture, Khamdiah Binti Khodari
  25. (2012) THE ROLE OF GENETIC POLYMORPHISMS AND HLA VARIANTS ON CLINICAL OUTCOMES IN MALAYSIAN RENAL TRANSPLANT PATIENTS ON CALCINEURIN INHIBITORS, RHANYE MAC GUAD
  26. (2012) Pharmacokinetic of a novel tetrahydrobiopterine Analogue,, Yusmaidie Aziz
  27. (2012) IN VITRO TOXICOLOGICAL STUDIES OF MITRAGYNA SPECIOSA, KONG WAI MUN
  28. (2012) Determination of the effective route(s) of administration for bioflavonoids as anti-dengue virus agents in animal model, Ehsan Moghaddam
  29. (2011) THE PHARMACOKINETICS AND PHARMACODYNAMICS OF TETRAHYDROBIOPTERIN AND ITS ANALOGUE,WSG1002, MOHD YUSMAIDIE BIN AZIZ
  30. (2011) Parabens, Body Care Cosmetics, Oestrogenicity and Breast Cancer The determination of parabens concentration in both human breast tumours and normal breast tissue., Shameem Shariff
  31. (2011) Gamma-Delta Tocotrienol as potential maintenance treatment in women with metastatic breast cancer, Puvanesewari A/PMeganathan
  32. (2011) Development of Suppository based for the transdermal delivery of Insulin, Sritharan Nair
  33. (2008) Development of Testosterone transdermal drug delivery system, Didi Erwandi

TEACHING


Master
  1. (2023) DXGC6180 - Kursus Sains Asas Perubatan (Bms) Sesi 2020/2021, Fakulti Pergigian
  2. (2022) DXGC6180 - Kursus Sains Asas Perubatan (Bms) Sesi 2020/2021, Fakulti Pergigian
  3. (2021) DXGC6180 - Kursus Sains Asas Perubatan (Bms) Sesi 2020/2021, Fakulti Pergigian
  4. (2017) DXGC6180 - Basic Medical Science
  5. (2016) DIA -
Bachelor
  1. (2023) UMMP- - Ummp1001
  2. (2023) MIC3010 - Advances in Medical Pharmacology
  3. (2023) MIX3003 - Drugs: from Target to Market
  4. (2023) DIA2006 - Pharmacology
  5. (2023) MID1009 - Pharmacology in Nursing
  6. (2023) MIC2004 - Principles in Pharmacology and Toxicology
  7. (2022) NA - Ummp
  8. (2022) MIA 2001 - Universiti Malaya Medical Programme (Ummp)
  9. (2022) MIC3010 - Advances in Medical Pharmacology
  10. (2022) MIX3003 - Drugs: from Target to Market
  11. (2022) DIA2006 - Pharmacology
  12. (2022) MID1009 - Pharmacology in Nursing
  13. (2021) UMMP - Ummp Stage 1,2 and 3.3
  14. (2021) MIC3010 - Advances in Medical Pharmacology
  15. (2021) DIA2006 - Pharmacology
  16. (2021) MID1009 - Pharmacology in Nursing
  17. (2020) MIA 1001 -
  18. (2019) DIA2006 - Pharmacology
  19. (2019) MIX3003 - Elektif
  20. (2018) DIA2006 - Pharmacology
  21. (2018) MIC3010 - Advances in Medical Pharmacology
  22. (2017) DIA2006 -
  23. (2017) DIA2006 - Pharmacology
  24. (2017) MBBS - Pharmacology
  25. (2017) MDEB4401 - Advanced Medical Pharmacology
  26. (2017) MIA 1001 - University Malaya Medical Programme
  27. (2017) MIC3010 - Advances in Medical Pharmacology
  28. (2017) MID1009 - Pharmacology in Nursing
  29. (2017) MID1009 - Nursing
  30. (2017) UMMP - University Malaya Medical Programme
  31. (2016) DIA2006 - Pharmacology
  32. (2016) MIA 1001 - University Malaya Medical Programme
  33. (2016) MID1009 - Pharmacology in Nursing
  34. (2016) MWEF3101 - Clinical Pharmacokinetics
  35. (2015) DIA2006 - Pharmacology
  36. (2015) MID1009 - Pharmacology in Nursing
  37. (2014) DNED2101 - Pharmacology
  38. (2014) DNED2101 - Pharmacology
  39. (2014) MDEB4401 - Advanced Medical Pharmacology
  40. (2014) MPEP2122 - Pharmacology
  41. (2014) MWEF2103 - Central Nervous System & Therapy
  42. (2011) DNED2101 - Pharmacology for Dentistry
  43. (2011) MBBS III - Clinicopharmacokinetics
  44. (2010) DNED2101 - Pharmacology for Dentistry
  45. (2010) MBBS - Pharmacology
  46. (2010) MDEB3401 - Advanced Medical Pharmacology
  47. (2010) MDEB3401 - Advanced Medical Pharmacology
  48. (2010) MWEF1108 - Principle of Drug Actions and Peripheral Nervous System
  49. (2009) MDEB2201 - Principles of Pharmacology and Toxicology
  50. (2009) MDEB3401 - Advanced Medical Pharmacology
  51. (2009) MWEF1108 - Principles of Drug Action & Peripheral Nervous System
  52. (2009) MWEF1108 - Principles of Drug Action & Peripheral Nervous System

SOCIAL RESPONSIBILITY ACTIVITIES


  • Technical,Assessor Under Skim Akreditasi Makmal Malaysia, (30 Nov 2022 - 30 Nov 2040) (National)
  • Member of The Reviewers Board of The Deanship of Scientific Research Jazan University, (12 May 2020 - 12 May 2021)
  • Ahli Jawatankuasa Penilaian Dana Penyelidikan Kementerian Pengajian Tinggi, (01 Mar 2020 - 31 Dec 2021)
  • Panel Penilai Permohonan Hubert Curien Partnership - Hibiscus, (06 Feb 2020 - 06 Mar 2020)
  • Ahli Jawatankuasa Kajia Biequivalence Kebangsaan, Ministry of Health Malaysia, (01 Feb 2020 - 31 Jan 2021)
  • Member of The National Committee for Clinical Research (Nccr), Ministry of Health Malaysia, (06 Dec 2019 - 05 Dec 2022)
  • Ahli Mesyuarat Kumpulan Kerja Teknikal (Twg) Untuk Kajian Bioekuivalens, (20 Dec 2016 - 20 Dec 2016)
  • Panellist for Human Life Advancment Foundation (Hlaf) Scholarship Interview, (17 Nov 2016 - 17 Nov 2016)
  • Reviewer for The Journal of Chromatographic Science, (07 Nov 2016 - 07 Nov 2016)
  • Instructor for Bioequivalence Workshop, (11 May 2015 - 15 May 2015)
  • Reviewer for Biomedical Chromatography Journal, (01 Jan 2015 - 01 Jan 2021)
  • Speaker for The in House Advance Course On Ba/Be for Npcb Officer, (05 Apr 2012 - 05 Apr 2012)
  • Reviewer for The Journal of Chromatographic Sciences, (01 Jan 2011)

COURSE ATTENDED


Internal / External Course
EXTERNAL COURSE
  1. 1ST CONFERENCE IN ASIA PACIFIC ON RECENT ISSUES IN GLP, Shanghai (10 Jan 2011 - 14 Jan 2011)
  2. 6TH. WORKSHOP ON RECENT ISSUES IN BIOANALYSIS, San Antonio Texas (28 Mar 2012 - 29 Mar 2012)
  3. LCMSMS BIOANALYTICAL ADVANCED METHOD DEVELOPMENT, San Antonio Texas (26 Mar 2012 - 26 Mar 2012)
  4. BNP RETREAT 2014, Cheringin Hills Spa & Resort, Pahang (05 Mar 2014 - 06 Mar 2014)
  5. UM-LMIF TRANSLATIONAL MEDICINE SHORT COURSE, Sime Darby Convention Center (08 Dec 2014 - 12 Dec 2014)
  6. SKIM AKREDITASI MAKMAL MALAYSIA (SAMM): WORKSHOP ON SAMM ACCREDITATION PRPCESS AND ASSESSMENT FOR MS ISO/IES 17025:2017 ASSESSORS, Department of Standards Malaysia, Century Square Cyberjaya (12 Nov 2018 - 13 Nov 2018)
  7. ASIA PACIFIC ISSX REGIONAL MEETING, Tainan (21 Apr 2010 - 26 Apr 2011)
  8. METABOLOMICS APPROACHES IN MEDICAL PLANT RESEARCH, Uitm, Puncak Alam, Shah Alam (14 Aug 2017 - 15 Aug 2017)
  9. BIOANALYTICAL METHOD VALIDATION AND SAMPLE ANALYSIS: CHALENGES, SOLUTIONS, APPLICATIONS, GLOBAL INDUSTRY STANDARDS AND NEW REGULATIONS, San Antonio Texas (27 Mar 2012 - 27 Mar 2012)
  10. AL 406 LEADERSHIP STYLE & CHARACTERISTIC, Kampus Akept Bandar Enstek Nilai (08 Mar 2017 - 09 Mar 2017)
  11. 6TH WORKSHOP ON RECENT ISSUES IN BIOANALYSIS (6TH WRIB), San Antonio Texas (25 Mar 2012 - 30 Mar 2012)
  12. NEXERA HPLC LAUNCH, Sentosa (03 Aug 2010 - 06 Aug 2010)
  13. BIOETHICS WORKSHOP, University Malaya Medical Centee (17 Aug 2016 - 17 Aug 2016)
  14. SAS ENTERPRISE GUIDE: ANOVA, REGRESSION & LOGISTIC REGRESSION, Sas Training Center, Kl Sentral, Kuala Lumpur (04 Mar 2009 - 06 Mar 2009)
CONFERENCE
  1. 27TH SCIENTIFIC MEETING OF MALAYSIAN SOCIETY OF PHARMACOLOGY AND PHYSIOLOGY, Ms Garden Hotel Kuantan Pahang (06 Sep 2013 - 08 Sep 2013)
  2. FORUM JABATAN STANDARD MALAYSIA BERSAMA PENILAI AKREDITASI BAGI SKIM SAMM CT/MIBAS/MYPTP 2022, Bangi Resort Hotel, Bangi (31 Oct 2022 - 31 Oct 2022)
  3. THE 5TH INTERNATIONAL MEDITERRANEAN SYMPOSIUM ON MEDICINAL AND AROMATIC PLANTS, Cappadocia, Turkey (23 Apr 2019 - 29 Apr 2019)
  4. UMSLTC 2022, Pullman Hotel Bangsar (25 Jul 2022 - 26 Jul 2022)
  5. INTERNATIONAL CONFERENCE ON MEDICINAL HERBS & ADDICTION TREATMENT, Pullman Bangsar Kl (28 Sep 2022 - 29 Sep 2022)
  6. BIOSIMILAR CARNIVAL 2018: CREATING COMMUNITY AWARENESS TOWARDS PEOPLE'S HEALTH & WELLNESS IMPROVEMENT INITIATIVE, Inno Bio Ventures Sdn Bhd. Putra Nilai Negeri Sembilan (29 Oct 2018 - 30 Oct 2018)
  7. JOIN 19TH NORTH AMERICAN ISSX MEETING & 29TH JSSX MEETING, San Francisco, Usa (18 Oct 2014 - 24 Oct 2014)
  8. 18TH WORLD CONGRESS OF BASIC AND CLINICAL PHARMACOLOGY, Kyoto, Japan (30 Jun 2018 - 07 Jul 2018)
  9. ASCEPT ANNUAL SCIENTIFIC MEETING 2013, Melbourne, Australia (30 Nov 2013 - 05 Dec 2013)
  10. INTERNATIONAL CONFERENCE ON TOXICOLOGY AND CLINICAL PHARMACOLOGY, Rome (13 Dec 2017 - 17 Dec 2017)
  11. APSA 2016 ANNUAL CONFERENCE, University of Sydney Australia (01 Dec 2016 - 06 Dec 2016)
  12. INTERNATIONAL CONFERENCE ON PHARMACEUTICS AND DRUG DELIVERY 2022, Dubai (13 Nov 2022 - 16 Nov 2022)
INTERNAL COURSE- ORGANIZED BY PTJ
  1. C3BIRD-UM GLP & GCP TRAINING, Penganjuran Kursus Secara Atas Talian (Online) (26 Oct 2021 - 26 Oct 2021)
  2. C3BIRD-UM GLP & GCP TRAINING, Penganjuran Kursus Secara Atas Talian (Online) (28 Oct 2021 - 28 Oct 2021)
  3. C3BIRD-UM GLP & GCP TRAINING, Penganjuran Kursus Secara Atas Talian (Online) (27 Oct 2021 - 27 Oct 2021)
  4. C3BIRD-UM GLP & GCP TRAINING, Penganjuran Kursus Secara Atas Talian (Online) (29 Oct 2021 - 29 Oct 2021)
  5. BENGKEL TEAM BUILDING, Asia Camp, Jalan Ampang Pechah, 44000 Kuala Kubu Baru, Selangor Darul Ehsan (16 Aug 2018 - 16 Aug 2018)
COURSES ORGANIZED BY PTJ
  1. 16TH WORLD CONGRESS OF BASIC AND CLINICAL PHARMACOLOGY DI COPENHAGEN, DENMARK, Copenhagen, Denmark (17 Jul 2010 - 23 Jul 2010)
  2. PROGRAM MAJU DIRI STAF , Bilik Kuliah, Jabatan Farmakologi, Fakulti Perubatan (21 May 2015 - 21 May 2015)
  3. TATAKELAKUAN DAN TATATERTIB, Auditorium Tj Danaraj, Fakulti Perubatan (27 Jan 2017 - 27 Jan 2017)
  4. MEASUREMENT UNCERTAINTY BY INFOKINETIC, Fakulti Perubatan, Universiti Malaya (10 Jun 2010 - 11 Jun 2010)
INTERNAL COURSE
  1. KURSUS ESSENTIALS OF BUILDING A GLOBAL NETWORK, Auditorium Rimba Ilmu, Universiti Malaya (26 Apr 2012 - 26 Apr 2012)