Curriculum Vitae

PROF. DR. WONG POOI FONG

Professor
  • Department of Pharmacology
    Faculty of Medicine
  • wongpf
  • 0379672065

AREAS OF EXPERTISE

  • AGING
    Pathogenesis of Aging-related diseases
  • MOLECULAR PHARMACOLOGY
    Mechanisms of Drugs Action
  • CELLULAR SENESCENCE
    Molecular Mechanism of Aging
  • VIROLOGY
    Dengue Pathogenesis and Diagnostics

ACADEMIC QUALIFICATION

  • PhD (Cancer Biology), (Canser Biology)
    Universiti Malaya (UM)
  • MMedSc (Virology), (Molecular Virology)
    Universiti Malaya (UM)
  • DipTropMed (Virology), (Virology)
    Nagasaki University
  • BBioMedSc(Hons), (Bioperubatan)
    Universiti Malaya (UM)

ADMINISTRATIVE DUTIES

  • Task Force Leader
    01 Jan 2024 - 31 Dec 2025 (Faculty)
  • Head of Unit, Business Pod (Animal Experimental Unit), UM Innovations Sdn Bhd
    20 Nov 2017 - 31 Dec 2024 (University Malaya)
  • Nursing Courses Coordinator (MTEJ2112 and MID1009)
    01 Jul 2016 - present (Department of Pharmacology, Faculty of Medicine)
  • Director, Semio Technology Sdn Bhd (860504 W)- UM Spin-Off Company
    01 Nov 2011 - present (National)
  • Internal Auditor, ISO/IEC 17025
    24 Nov 2015 - present (University Malaya)
  • Course Coordinator
    03 Oct 2022 - 30 Sep 2024 (Department of Pharmacology, Faculty of Medicine)
  • Head of Unit
    01 Jan 2022 - 31 Dec 2023 (Dean Office, Faculty of Medicine)
  • Coordinator
    01 Oct 2021 - 30 Sep 2022 (Department of Pharmacology, Faculty of Medicine)
  • Team Leader (Internal Auditor Research Laboratories)
    15 Oct 2018 - 02 Nov 2018 (Dean Office, Faculty of Medicine)
  • Internal Auditor Research Laboratories
    10 Feb 2017 - 09 Feb 2018 (Dean Office, Faculty of Medicine)
  • Council Member, Malaysian Society for Molecular Biology and Biotechnology
    20 Aug 2015 - 19 Aug 2017 (National)
  • Co-coordinator Biomedical Science Program (MDEB3401)
    27 Jan 2014 - 26 Jan 2016 (Department of Pharmacology, Faculty of Medicine)
  • Co-coordinator Biomedical Science Program (MDEB2201)
    27 Jan 2014 - 26 Jan 2016 (Department of Pharmacology, Faculty of Medicine)
  • Co-coordinator Biomedical Science Program (MDEB3401)
    22 Jan 2009 - 26 Jan 2014 (Department of Pharmacology, Faculty of Medicine)
  • Co-coordinator Biomedical Science Program (MDEB2201)
    22 Jan 2009 - 25 Jan 2014 (Department of Pharmacology, Faculty of Medicine)
  • Quality Manager
    01 Jun 2010 - 31 May 2012 (Department of Pharmacology, Faculty of Medicine)
  • Academic Advisor MBBS Phase II
    14 May 2010 - 13 May 2011 (Department of Pharmacology, Faculty of Medicine)
  • Group Coordinator Community Case Studies Program (Module: Doctor, Patient, Health & Society) MBBS2 (2009/2010)
    29 Jul 2009 - 30 Jul 2010 (Department of Pharmacology, Faculty of Medicine)

MEMBERSHIPS

  • ASSOCIATE EDITOR OF ASIA PACIFIC JOURNAL OF MOLECULAR BIOLOGY AND BIOTECHNOLOGY (APJMBB), ASSOCIATE EDITOR
    2018 to 2024 (International)
  • ASSOCIATION FOR ASSESSMENT AND ACCREDITATION OF LABORATORY ANIMAL CARE (AAALAC), AD-HOC CONSULTANT, MEMBER
    2015 to present (International)
  • ASIA-PACIFIC JOURNAL OF MOLECULAR BIOLOGY AND BIOTECHNOLOGY, COMMITTEE MEMBER
    2018 to 2022 (International)
  • INSTITUTIONAL BIOSAFETY AND BIOSECURITY COMMITTEE, MEMBER
    2019 to 2021 (University)
  • THE JOURNAL OF UNIVERSITY OF MALAYA MEDICAL CENTRE (JUMMEC), COMMITTEE MEMBER
    2012 to 2021 (International)
  • FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, TOPIC EDITOR, MEMBER
    2020 to 2020 (International)
  • INTERNATIONAL ZEBRAFISH SOCIETY, MEMBER
    2019 to 2020 (International)
  • WHO COLLABORATING CENTRE (WHOCC), ARBOVIRUS REFERENCE AND RESEARCH, MEMBER
    2018 to 2019 (International)
  • MALAYSIAN SOCIETY FOR MOLECULAR BIOLOGY AND BIOTECHNOLOGY, ACTIVE MEMBER
    2014 to 2018 (University)
  • ENDEAVOUR AWARDS ALUMNI NETWORK, LIFE MEMBERSHIP
    Since 2011 (International)

AWARD AND STEWARDSHIP

  • EXCELLENT LECTURER AWARD (SCIENCE)
    University of Malaya, 2023 (University)
  • EXCELLENCE SERVICE AWARD
    University of Malaya, 2023 (University)
  • AAALAC Global 3Rs Publication Award
    AAALAC International , 2022 (International)
  • Leaders in Innovation Fellowship (LIF)
    Royal Academy of Engineering, 2022 (International)
  • Gold Award, International Conference and Exposition on Inventions by Institutions of Higher Learning (Pecipta 2019)
    Ministry of Education, Malaysia, 2019 (International)
  • Gold Medal, International Invention, Innovation and Technology Exhibition
    Malaysian Invention and Design Society, 2019 (International)
  • EXCELLENCE SERVICE AWARD
    University of Malaya, 2018 (University)
  • Best Lecturer in Pharmacology (Postgraduate Studies)
    Faculty of Medicine, 2017 (University)
  • CERTIFICATE OF EXCELLENT SERVICE
    University of Malaya, 2017 (University)
  • CERTIFICATE OF EXCELLENT SERVICE
    University of Malaya, 2016 (University)
  • Finalist - National Innovation Award (Anugerah Inovasi Negara)
    Ministry of Science, Technology and Innovation (MOSTI), 2015 (National)
  • CERTIFICATE OF EXCELLENT SERVICE
    University of Malaya, 2014 (University)
  • Outstanding Young Researcher
    University of Malaya Excellence Award, 2014 (University)
  • US Department of State's Biosecurity Engagement Program (BEP) Travel Award
    Bureau of International Security and Nonproliferation, Department of State, US, 2014 (International)
  • Sijil Perkhidmatan Cemerlang (Excellence Service Certificate)
    University of Malaya, 2014 (University)
  • EXCELLENCE SERVICE AWARD
    University of Malaya, 2012 (University)
  • Endeavour Research Fellowship
    The Government of Australia, 2008 (International)
  • National Scientific Foundation Scholarship
    MOSTI, Malaysia, 2002 (National)
  • Research Fellowship
    Japan International Cooperation Agency (JICA), 2000 (International)
  • Young Researcher Award for Molecular Biology
    Malaysian Society for Molecular Biology and Biotechnology, 1999 (National)

PUBLICATIONS

Article in Journal
WoS
  1. Ang, Jing-Jie; Shivashekaregowda, Naveen Kumar Hawala; Yow, Hui-Yin; Rizwan, Farzana; Wong, Pooi-Fong; Jantan, Ibrahim; Omar, Maizatul Hasyima; Misnan, Norazlan Mohmad; Low, Bin-Seng (2024). Stimulatory effect of eurycomanone from Eurycoma longifolia Jack roots on dopamine secretion in human neuroblastoma SH-SY5Y cell line, NATURAL PRODUCT RESEARCH. . doi:10.1080/14786419.2024.2383272
  2. Noor, Suzita Mohd; Wong, Chee Ern David; Wong, Pooi-Fong; Norazit, Anwar (2024). Generation of glial cell-derived neurotrophic factor (gdnf) morphants in zebrafish larvae by cerebroventricular microinjection of vivo morpholino, CELLULAR SENESCENCE AND AGING. 181, 17-32. doi:10.1016/bs.mcb.2022.09.004
  3. Tong, Kind-Leng; Zuhdi, Ahmad Syadi Mahmood; Wong, Pooi-Fong (2024). THE ROLE OF MIR-134-5P IN 7-KETOCHOLESTEROL-INDUCED HUMAN AORTIC ENDOTHELIAL DYSFUNCTION, EXCLI JOURNAL. 23, 1073-1090. doi:10.17179/excli2024-7342
  4. Hipolith, Mathias -Mathew; Khor, Boon-Keat; Hirasawa, Yusuke; Murugaiyah, Vikneswaran; Lee, Chong -Yew; Morita, Hiroshi; Wong, Pooi-Fong; Chan, Kit -Lam (2023). Quassinoids from Eurycoma longifolia Jack roots and their potential inhibitory activity against human benign prostatic hyperplasia cells (BPH-1) and testosterone-induced BPH rat model, FITOTERAPIA. 166. doi:10.1016/j.fitote.2023.105468
  5. Khor, Yi-Sheng; Wong, Pooi-Fong (2023). MicroRNAs-associated with FOXO3 in cellular senescence and other stress responses, BIOGERONTOLOGY. . doi:10.1007/s10522-023-10059-6
  6. Wong, Li Ping; Alias, Haridah; Tan, Kit Mun; Wong, Pooi Fong; Murugan, Dharmani Devi; Hu, Zhijian; Lin, Yulan (2023). Exploring the perspectives of pharmaceutical experts and healthcare practitioners on senolytic drugs for vascular aging-related disorder: a qualitative study, FRONTIERS IN PHARMACOLOGY. 14. doi:10.3389/fphar.2023.1254470
  7. Wong, Pooi-Fong; Dharmani, Murugan; Ramasamy, Thamil Selvee (2023). Senotherapeutics for mesenchymal stem cell senescence and rejuvenation, DRUG DISCOVERY TODAY. 28(1). doi:10.1016/j.drudis.2022.103424
  8. Yap, Yi-Jing; Wong, Pooi-Fong; AbuBakar, Sazaly; Sam, Sing-Sin; Shunmugarajoo, Anusha; Soh, Yih-Harng; Misbah, Suzana; Rahman, Ahmad Kashfi Ab (2023). The clinical utility of CD163 in viral diseases, CLINICA CHIMICA ACTA. 541. doi:10.1016/j.cca.2023.117243
  9. Lee, Siam-Yee; Wong, Pooi-Fong; Jamal, Juliana; Roebuck, Margaret M. (2022). Naturally-derived endoplasmic reticulum stress inhibitors for osteoarthritis?, EUROPEAN JOURNAL OF PHARMACOLOGY. 922. doi:10.1016/j.ejphar.2022.174903
  10. Roebuck, Margaret M.; Jamal, Juliana; Lane, Brian; Wood, Amanda; Santini, Alasdair; Wong, Pooi-Fong; Bou-Gharios, George; Frostick, Simon P. (2022). Cartilage debris and osteoarthritis risk factors influence gene expression in the synovium in end stage osteoarthritis, KNEE. 37, 47-59. doi:10.1016/j.knee.2022.05.001
  11. Sawai, Sakunie; Wong, Pooi-Fong; Ramasamy, Thamil Selvee (2022). Hypoxia-regulated microRNAs: the molecular drivers of tumor progression, CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY. . doi:10.1080/10409238.2022.2088684
  12. Tong, Kind-Leng; Tan, Ke-En; Lim, Yat-Yuen; Tien, Xin-Yi; Wong, Pooi-Fong (2022). CircRNA-miRNA interactions in atherogenesis, MOLECULAR AND CELLULAR BIOCHEMISTRY. . doi:10.1007/s11010-022-04455-8
  13. Wong, Pooi-Fong (2022). Editorial: Cellular Senescence: Causes, Consequences and Therapeutic Opportunities, FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 10. doi:10.3389/fcell.2022.884910
  14. Khor, ES; Noor, SM; Wong, PF (2021). MiR-107 inhibits the sprouting of intersegmental vessels of zebrafish embryos, PROTOPLASMA. . doi:10.1007/s00709-021-01695-1
  15. Maeno, Hinata; Wong, Pooi-Fong; AbuBakar, Sazaly; Yang, Ming; Sam, Sing-Sin; Jamil-Abd, Juraina; Shunmugarajoo, Anusha; Mustafa, Mahiran; Said, Rosaida Md; Mageswaren, Eashwary; Azmel, Azureen; Mat Jelani, Anilawati (2021). A 3D Microfluidic ELISA for the Detection of Severe Dengue: Sensitivity Improvement and Vroman Effect Amelioration by EDC-NHS Surface Modification, MICROMACHINES. 12(12). doi:10.3390/mi12121503
  16. Morrissey, K., Chung, I., Morse, A., Parthasarath, S., Roebuck, M., Tan, M., . . . Frostick, S. (2021). The Effects of Air Quality on Hospital Admissions for Chronic Respiratory Diseases in Petaling Jaya, Malaysia, 2013-2015. Atmosphere, 12(8), 10. doi: 10.3390/atmos12081060
  17. Murugan, D. D., Balan, D., & Wong, P. F. (2021). Adipogenesis and therapeutic potentials of antiobesogenic phytochemicals: Insights from preclinical studies. Phytotherapy Research, 35(11), 5936-5960. doi: 10.1002/ptr.7205
  18. Shu, Meng-Hooi; Wong, Pooi-Fong; Sam, Sing-Sin; Loong, Shih-Keng; Teoh, Boon-Teong; AbuBakar, Sazaly (2021). Intracellular calcium ions facilitate dengue virus entry into endothelial cells and compromise endothelial barrier integrity, ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE. 14(11), 505-516. doi:10.4103/1995-7645.331257
  19. Tiong, V., Loong, S. K., Wali, H. A. M., Tan, K. K., Jee, P. F., Lim, F. S., . . . Abubakar, S. (2021). Isolation of Streptococcus cuniculi from corneal lesion in laboratory-raised mice. Journal of Veterinary Medical Science, 83(2), 280-284. doi: 10.1292/jvms.20-0070
ESCI
  1. Tien, Xin-Yi; Lee, Yean Kee; Wong, Pooi-Fong; Khor, Yi-Sheng; Murugan, Dharmani Devi; Abdullah, Iskandar (2024). Anti-senescence effects of 4-methoxychalcone and 4-bromo-4'-methoxychalcone on human endothelial cells, DRUG DISCOVERIES AND THERAPEUTICS. 18(3), 199-206. doi:10.5582/ddt.2024.01034
  2. Jamal, Juliana; Roebuck, Margaret M.; Wood, Amanda; Santini, Alasdair; Bou-Gharios, George; Frostick, Simon P.; Wong, Pooi-Fong (2022). Histopathological dataset and demographic details of synovial tissues from patients with end-stage osteoarthritis, soft tissue and traumatic injuries of the knee, DATA IN BRIEF. 42. doi:10.1016/j.dib.2022.108082
Scopus
  1. Soh L.-J., Lee S.-Y., Roebuck M.M., Wong P.-F. (2024). Unravelling the interplay between ER stress, UPR and the cGAS-STING pathway: Implications for osteoarthritis pathogenesis and treatment strategy, Life Sciences. 357. doi:10.1016/j.lfs.2024.123112
Others
  1. Khor, Yi-Sheng and Wong, Pooi-Fong (2023). MicroRNAs-associated with FOXO3 in cellular senescence and other stress responses. Biogerontology.
  2. Chan CK, Tong KL, Wong PF, Abdul Kadir H (2020). Deoxyelephantopin induces ROS-mediated autophagy and apoptosis in human colorectal cancer in vitro and in vivo. Asian Pacific Journal of Tropical Biomedicine.10(3): 120-135. DOI:10.4103/2221-1691.276318
  3. Jamal J, Roebuck MM, Lee SY, Frostick SP, Abbas AA, Merican AM, Teo SH, Wood A, Tan SL, Bou-Gharios G, Wong PF (2020). Modulation of the mechanical response of synovial fibroblasts by osteoarthritis-associated inflammatory stressors. The International Journal of Biochemistry & Cell Biology, Available online 13 July 2020, 105800. https://doi.org/10.1016/j.biocel.2020.105800
  4. Khor, ES., Wong, PF (2020). The roles of MTOR and miRNAs in endothelial cell senescence. Biogerontology. https://doi.org/10.1007/s10522-020-09876-w
  5. Wong LP, Alias H, Wong PF, Lee HY and AbuBakar A (2020). The use of the health belief model to assess predictors of intent to receive the COVID-19 vaccine and willingness to pay. Human Vaccines & Immunotherapeutics. 16(9):2204-2214
  6. Wong LP, Wong PF, AbuBakar S (2020).Vaccine hesitancy and the resurgence of vaccine preventable diseases: The way forward for Malaysia, a Southeast Asian country. Human Vaccines & Immunotherapeutics 16(7), 1511-1520.
  7. Wong LP, Wong PF, Megat Hashim MMAA, et al (2020). Multidimensional social and cultural norms influencing HPV vaccine hesitancy in Asia. Human Vaccines & Immunotherapeutics. 16(7);1611-1622
  8. Dorasamy MS, Ab A, Nellore K, Wong PF. (2018). Synergistic inhibition of melanoma xenografts by Brequinar sodium and Doxorubicin. Biomed Pharmacother. 110:29-36. doi: 10.1016/j.biopha.2018.11.010
  9. Khor ES, Noor SM and Wong PF (2019). Understanding The Role Of ztor In Aging-Related Diseases Using Zebrafish Model. In Vivo, 33 (6) 1713-1720; doi:10.21873/invivo.11661
  10. Wong PF, Tong KL, Jamal J, Khor ES, Lai SL and Mustafa MR (2019). Senescent Huvecs-Secreted Exosomes Trigger Endothelial Barrier Dysfunction In Young Endothelial Cells. EXCLI Journal 18:764-776. https://doi.org/10.17179/excli2019-1505
  11. Wong PF, Wong LP, AbuBakar S (2019). Diagnosis of severe dengue: Challenges, needs and opportunities. J Infection and Public Health. Available on 10 Aug 2019. DOI: 10.1016/j.jiph.2019.07.012.
  12. Balan D, Chan KL, Murugan D, AbuBakar S, Wong PF. (2018). Antiadipogenic effects of a standardized quassinoids enriched fraction and eurycomanone from Eurycoma longifolia. Phytother Res. 32(7):1332-1345. DOI:10.1002/ptr.6065
  13. Khor ES, Wong PF. Endothelial Replicative Senescence Delayed by the Inhibition of MTORC1 Signaling Involves MicroRNA-107. Int J Biochem Cell Biol. 2018 May 29. pii: S1357-2725(18)30128-6. doi: 10.1016/j.biocel.2018.05.016.
  14. Lai SL, Mustafa MR, Wong PF. Panduratin A induces protective autophagy in melanoma via the AMPK and mTOR pathway. Phytomedicine. 2018 Mar 15;42:144-151. doi: 10.1016/j.phymed.2018.03.027
  15. Tong KL, Mahmood Zuhdi AS, Wan Ahmad WA, Vanhoutte PM, de Magalhaes JP, Mustafa MR and Wong PF. Circulating MicroRNAs in Young Patients with Acute Coronary Syndrome. Int. J. Mol. Sci. 2018, 19, 1467; doi:10.3390/ijms19051467
  16. Dorasamy MS, Choudhary B, Nellore K, Subramanya H, Wong PF (2017). Dihydroorotate dehydrogenase Inhibitors Target c-Myc and Arrest Melanoma, Myeloma and Lymphoma cells at S-phase. J Cancer; 8(15):3086-3098. doi:10.7150/jca.14835. Available from http://www.jcancer.org/v08p3086.htm
  17. Loong SK, Tan KK, Sulaiman S, Wong PF, AbuBakar S. (2017). Draft genome of Bordetella pseudohinzii BH370 isolated from trachea and lung tissues of a laboratory mouse. Genom Data. 2017 Mar 21;12:69-70. doi: 10.1016/j.gdata.2017.03.004. eCollection 2017
  18. Voon YL, Wong PF, Khoo ASB. (2017). Nutlin-3, a p53-Mdm2 antagonist for nasopharyngeal carcinoma treatment. Mini-Reviews in Medicinal Chemistry. 18(2). DOI : 10.2174/1389557517666170717125821
  19. Wong PF, Jamal J, Tong KL, Khor ES, Yeap CE, Jong HL, Lee ST, Mustafa MR, Abubakar S (2017). Deregulation of hsa-miR-20b expression in TNF-alpha-induced premature senescence of human pulmonary microvascular endothelial cells. Microvascular Research 2017; 114:26-33. https://doi.org/10.1016/j.mvr.2017.06.002
  20. Ab-Rahman HA, Rahim H, AbuBakar S, Wong PF. Macrophage Activation Syndrome-Associated Markers in Severe Dengue. Int J Med Sci 2016; 13(3):179-186. doi:10.7150/ijms.13680
  21. Khor ES, Noor SM, Wong PF. Expression of zTOR- associated microRNAs in zebrafish embryo treated with rapamycin. Life Sciences 2016, Apr 1;150:67-75. doi: 10.1016/j.lfs.2016.02.076
  22. Loong SK, Mahfodz NH, Che Mat Seri NAA, Mohamad Wali HA, A. Gani SA, Wong PF, AbuBakar S. (2016). Genetic characterization of commensal Escherichia coli isolated from laboratory rodents. SpringerPlus, 5(1), 1035. doi: 10.1186/s40064-016-2745-9
  23. Loong SK, Mahfodz NH, Mohamad Wali HA, A. Talib SA, Ahmad Nasrah SN, Wong PF, AbuBakar S. (2016). Molecular and antimicrobial analyses of non-classical Bordetella isolated from a laboratory mouse. Journal of Veterinary Medical Science, 78(4), 715-717. DOI: 10.1292/jvms.15-0472
  24. Hasliana Azrah Ab Rahman, Pooi Fong Wong, Hafiz Rahim , Juraina Abd Jamil, Kim Kee Tan, Syuhaida Sulaiman, Chai See Lum, Syarifah Faridah Syed Omar and Sazaly AbuBakar 2015. Dengue death with evidence of hemophagocytic syndrome and dengue virus infection in the bone marrow. Springer Plus
  25. Lai SL, Wong PF, Lim TK, Lin QS and Mustafa MR. Mechanisms of Panduratin A on A375 Melanoma Cells: A Quantitative and Temporal Proteomics Analysis. Proteomics. 2015 May;15(9):1608-21. doi: 10.1002/pmic.201400039.
  26. Lai SL, Wong PF, Lim TK, Lin QS and, Mustafa MR. ITRAQ-based proteomic identification of proteins involved in anti-angiogenic effects of Panduratin A on HUVECs. Phytomedicine 2015 Jan 15;22(1):203-12. doi: 10.1016/j.phymed.2014.11.016
  27. Tong KL, Chan KL, S AbuBakar, BS Low, Ma HQ, Wong PF. The in vitro and in vivo anti-cancer activities of a standardized quassinoids composition from Eurycoma longifolia on LNCaP human prostate cancer cells. PLoS One. 2015 Mar 31;10(3):e0121752. doi: 10.1371/journal.pone.0121752. eCollection 2015.
  28. Voon YL, Ahmad M, Wong PF, Husaini R, Ng WTW, Leong CO, Lane DL, Khoo ASB. Nutlin-3 sensitizes nasopharyngeal carcinoma cells to cisplatin-induced cytotoxicity. Oncology Reports 2015;34(4):1692-700. doi: 10.3892/or.2015.4177
  29. AbuBakar S, Shu MH, Johari J, Wong PF. Senescence Affects Endothelial Cells Susceptibility to Dengue Virus Infection. Int. J. Med. Sci. 2014; 11(6): 538- 544. doi:10.7150/ijms.7896
  30. Jamal J, Mustafa MR and Wong PF. Paeonol Protects Against Premature Senescence In Endothelial Cells By Modulating Sirtuin 1 Pathway. J Ethnopharmacol. 2014 Jun 11;154(2):428-36. doi: 10.1016/j.jep.2014.04.025
  31. Wong PF and Jong HL. The Relevance of microRNAs in Vascular Senescence. Journal of Health and Translational Medicine (JUMMEC). 2014; 17(2): 18-23. http://e-journal.um.edu.my/filebank/publish_epublication/JUMMEC/flipbook/8 27/index.html#p=2
  32. Gummadi VR, Rajagopalan S, Looi CY, Paydar M, Renukappa GA, Ainan BR, Krishnamurthy NR, Panigrahi SK, Mahasweta K, Raghuramachandran S, Rajappa M, Ramanathan A, Lakshminarasimhan A, Ramachandra M, Wong PF, Mustafa MR, Nanduri S, Hosahalli S. Discovery of 7-azaindole based anaplastic lymphoma kinase (ALK) inhibitors: Wild type and mutant (L1196M) active compounds with unique binding mode. Bioorg Med Chem Lett. 2013 Sep 1;23(17):4911-8. doi: 10.1016/j.bmcl.2013.06.071.
  33. Jong HL, Mustafa MR, Vanhoutte PM, AbuBakar S, Wong PF. 2013. MicroRNA 299-3p modulates replicative senescence in endothelial cells.Physiol Genomics. 2013 Apr 1;45(7):256-67. doi:10.1152/physiolgenomics.00071.2012
  34. Lee ST, Wong PF, He H, Hooper JD, Mustafa MR. 2013. Alpha-tomatine synergises with paclitaxel to enhance apoptosis of androgen-independent human prostate cancer PC-3 cells in vitro and in vivo. Phytomedicine. 2013 Aug 3. doi:pii: S0944-7113(13)00246-8. 10.1016/j.phymed.2013.07.002.
  35. Lee ST, Wong PF, He H, Hooper JD, Mustafa MR. 2013. Alpha-tomatine attenuation of in vivo growth of subcutaneous and orthotopic xenograft tumors of human prostate carcinoma PC-3 cells is accompanied by inactivation of nuclear factor-kappa B signaling. PLoS One. 2013;8(2):e57708.
  36. Wada A, Wong PF; Hojo H; Hasegawa M; Ichinose A; Llanes R; Kubo Y; Senba M and Ichinose Y. 2013. Alarin but not its alternative-splicing form, GALP (Galanin- like peptide) has antimicrobial activity. Biochem Biophys Res Commun. 2013 Mar 26. doi:pii: S0006- 291X(13)00461-0. 10.1016/j.bbrc.2013.03.045.
  37. Lai SL, Cheah SC, Wong PF, Noor SM and Mustafa MR. 2012. In vitro and In vivo Anti-angiogenic Actvities of Panduratin A. PLoS One. 2012;7(5):e38103.
  38. Wong P.F., Cheong W.F., Shu M.H., Teh C.H., Chan, K.L., AbuBakar S. Eurycomanone Suppresses Expression of Lung Cancer Cell Tumor Markers, Prohibitin, Annexin 1 and Endoplasmic Reticulum Protein 28. Phytomedicine 19 (2012) 138 144
  39. Zandi K, Teoh BT, Sam SS, Wong PF, Mustafa MR and AbuBakar S. 2012. Novel antiviral activity of baicalein against dengue virus. BMC Complementary and Alternative Medicine, 12:214 doi:10.1186/1472-6882-12- 214, Published: 9 November 2012
  40. Zandi, K., Lani, R., Wong, P.F., Teoh, B.T., Sam, S.S., Johari, J., Mustafa, M.R., AbuBakar, S. 2012. Flavone enhances dengue virus type-2 (NGC strain) infectivity and replication in vero cells. Molecules. 17(3):2437-45
  41. Antiviral activity of four types of bioflavonoid against dengue virus type-2. Zandi K, Teoh B.T., Sam S.S., Wong P.F., Mustafa M.R., AbuBakar S. Virology Journal 2011, 8:560
  42. Freeman L.M., Lam A., Petcu E., Smith R., Salajegheh A., Diamond P., Zannettino A., Evdokiou A., Luff J., Wong P.F., Khalil D., Waterhouse N., Vari F., Rice A.M., Catley L., Hart D.N.J. and Vuckovic S. 2011. Myeloma-Induced Alloreactive T Cells Arising in Myeloma-Infiltrated Bones Include Double-Positive CD8+CD4+ T Cells: Evidence from Myeloma-Bearing Mouse Model. J Immunol; Prepublished online 9 September 2011;doi:10.4049/jimmunol.1101202 http://www.jimmunol.org/content/early/2011/09/09/jimmun ol.1101202
  43. Lee ST, Wong PF, Cheah SC, Mustafa MR. 2011. Alpha- Tomatine Induces Apoptosis and Inhibits Nuclear Factor-Kappa B Activation on Human Prostatic Adenocarcinoma PC-3 Cells. PLoS ONE, 10.1371/journal.pone.0018915
  44. Wilkinson A., Bian L., Khalil D., Gibbons K., Wong P.F., Hart D.N.J., Harris M., Cotterill A., Vuckovic S. Type 1 Diabetic Children and siblings share a decrease in dendritic cell and monocyte numbers but are differentiated by expansion of CD4+T cells expressing IL-17. J Clin Cell Immunol 2011, S2: 001
  45. Zandi K, Teoh BT, Sam SS, Wong PF, Mustafa MR, AbuBakar S. In vitro antiviral activity of Fisetin, Rutin and Naringenin against Dengue virus Type-2. Journal of Medicinal Plants Research (2011) Vol. 5 (23), pp. 5534-5539.
  46. Wada A., Hasegawa M., Wong P.-F., Shirai E., Shirai N., Tan L.-J.,Llanes R., Hojo H., Yamasaki E., Ichinose A., Ichinose Y., and Senba M.2010. Direct binding of gangliosides to Helicobacter pylori. Glycobiology 20(6):668-78.
  47. Wong, P-.F., AbuBakar S. 2010. Comparative Transcriptional Study of the Effects of High Intracellular Zinc on Prostate Carcinoma Cells. Oncol Rep 23: 1501-1516.
  48. Wong, P-.F., AbuBakar S. 2010. Influence of high intracellular zinc on prostate cancer cells growth and transcriptional responses. International Journal of Molecular Medicine, Vol 26, Supplement 1, S68. Proceedings of Abstracts of the 15th World Congress on Advances in Oncology
  49. Wong, P-.F., Abubakar S. 2008. LNCaP prostate cancer cells are insensitive to zinc-induced senescence. J Trace Elem Med Biol 22(3): 242-7.
  50. Wong, P-.F., Abubakar, S. 2008. High intracellular Zn2+ ions modulate the VHR, ZAP-70 and ERK activities of LNCaP prostate cancer cells. Cell Mol Biol Lett 13(3): 375-90.
  51. AbuBakar S, Sam I-C, Wong PF, Mat Rahim N, Hooi PS, Roslan N. 2007. Reemergence of endemic Chikugunya,Malaysia. Emerg Infect Dis. 13(1):147-9
  52. Wong, P.F., Tan, L.J., Nawi, H. and AbuBakar, S. 2006. Proteomics Analysis of Red Alga, Gracilaria changii. Journal of Phycology 42(1):113 120.
  53. Wong, P.F. and AbuBakar, S. 2005. Post-Germination Changes In Hevea brasiliensis Seeds Proteome. Plant Science 169(2): 303 311.
  54. Mathenge, E. G. M., Parquet, M. d. C., Funakoshi, Y., Houhara, S., Wong, P.F., Ichinose, A., Hasebe, F, Inoue, S., and Morita, K. 2004. Fusion PCR generated Japanese encephalitis virus/dengue 4 virus chimera exhibits lack of neuroinvasiveness, attenuated neurovirulence, and a dual-flavi immune response in mice. Journal of General Virology 85(9) : 2503-2513.
  55. AbuBakar, S. and Wong, P.F. 2002. Re-Emergence Of Dengue 4 Virus. Malaysian Medical Journal 57(2) : 242-243.
  56. AbuBakar, S., Wong, P.F. and Chan, Y.F. 2002. Emergence of Dengue-4 virus Genotype IIA in Malaysia. Journal of General Virology 83, 2437-2442
Chapter in Books
  1. Noor SM, Wong CED, Wong PF, Norazit A. Generation of glial cell-derived neurotrophic factor (gdnf) morphants in zebrafish larvae by cerebroventricular microinjection of vivo morpholino. Methods Cell Biol. 2024;181:17-32. doi: 10.1016/bs.mcb.2022.09.004.
  2. Wong PF & AbuBakar S. 2011. Zinc Supplementation and Prostate Cancer. In Prostate Cancer - From Bench to Bedside, Ed. Philippe E. Spiess, Intech Open Access Publisher
Article in Proceeding
  1. A Santini, J Jamal, PF Wong, B Lane, A Wood, G Bou-Gharios, S Frostick, M Roebuck. 2022. BMI And Sex Impact Gene Expression in Synovial Tissues from Different Knee Pathologies. Orthopaedic ProceedingsVol. 104-B, No. SUPP_7
  2. J Jamal, PF Wong, B Lane, A Wood, G Bou-Gharios, A Santini, S Frostick, M Roebuck. 2022. Differential Gene Expression in Human Synovial Tissue Culture from Primary Explant Compared with Whole Synovium. Orthopaedic ProceedingsVol. 104-B, No. SUPP_7
  3. M. Roebuck, J. Jamal, P.F Wong, B. Lane, A. Wood, G. Bou-Gharios, S. Frostick, A. Santini. 2022. Cartilage Fragments And Inflammatory Aggregates In Synovial Intimal And Sub-Intimal Layers Reflect Deteriorating Joint Structures And Function. Orthopaedic ProceedingsVol. 104-B, No. SUPP_7
  4. PF Wong, J Jamal, A Santini, B Lane, A Wood, G Bou-Gharios, S Frostick, M Roebuck. 2022. Expression of Transcription Factors Differs in Synovial Biopsies from Different Knee Pathologies. Orthopaedic Proceedings 104 (SUPP_7), 70-70
  5. Tong KL, Zuhdi ASM, Wong PF (2021). The role of miR-134-5p in 7-ketocholesterol-induced human aortic endothelial cell dysfunction, p95, DOI: 10.3389/978-2-88971-008-9.
  6. Khor ES and Wong PF (2017). miR-107 Regulated Endothelial Replicative Senescence via mTOR Complex 1. Paper presented in Aging and Mechanism of Aging-Related Disease, 2017-05-15 to 2017-05-19, Keystone Symposia on Molecular and Cellular Biology.
  7. ES Khor and PF Wong. Inhibition of mTOF Complex 1 (mTORCI) Mitigates Replicative Senescence in Endothelial Cells. 21st Annual Malaysian Society for Molecular Biology and Biotechnology Meeting, 01 Oct 2014 to 03 Oct 2014, Monash University Malaysia, pp. 54
  8. Jamal J, Mustafa MR, Wong PF. Paeonol Protects Endothelial Cells from Stress‐Induced Premature Senescence by Activating Sirt1, Pharmacology and Physiology International Scientific Congress, Abstract no. 116
  9. KL Tong, ST Lee, S AbuBakar, KL Chan and PF Wong. Standardized-rich quassinoids Eurycoma longifolia fraction suppresses prostate cancer progression and bone marrow colony formation in vivo, Pharmacology and Physiology International Scientific Congress, Abstract 122
  10. SL Lai, PF Wong, TK Lim, QS Lin and MR Mustafa. Panduratin A Inhibits Angiogenesis by Targeting mTOR Pathway. Pharmacology and Physiology International Scientific Congress, Abstract No. 165
  11. Ab-Rahman HA, AbuBakar S and Wong PF. Hemophagocytosis- Associated Markers in Severe Dengue. LRGS Dengue Colloquim and Workshop, 11-14 June 2013, University Malaya, p. 13
  12. Jamal J, Mustafa MR, Wong PF. 2013. Paeonol Protects Endothelial Cells Against H2O2-Induced Senescence. International Conference on Natural Products and Health 2013 (NPH2013) School of Biological Sciences (SBS), Nanyang Technological University (NTU), Singapore, on 5-7 Sep, 2013, p.24
  13. Tong KL, AbuBakar S, Chan KL, Wong PF. 2013. Anti- protiferative potentials of standardized quassinoid- rich Eurycoma Iongifolia extract on prostate cancer cells., International Conference on Natural Products and Health 2013 (NPH2013) School of Biological Sciences (SBS), Nanyang Technological University (NTU), Singapore, on 5-7 Sep, 2013, p.26
  14. Jong HL, Mustafa MR, AbuBakar S and Wong PF. MicroRNA signature of pulmonary microvascular hyperpermeability in senescent pulmonary endothelial cells. 2012. 19th International Congress of BioMedical Science, University Medical Center Groningen, Netherlands, pp 245.
  15. Teoh BT, Sam SS, Tan KK, Danlami MB, Johari J, Shu MH, Pang SP, Nor-Amdan NA, Hashim SH, Tiong V, Abd- Jamil J, MatRahim N, Misbah S, Wong PF, Zandi K, Mahadi NM, Abubakar S. Purifying selection in the evolution of dengue virus type 1 in Malaysia. International Journal of Infectious Diseases, Vol: 16, Pages: E273-E273, 2012
  16. Wong PF and AbuBakar S. Influence of high intracellular zinc on prostate cancer cells growth and transcriptional responses, International Journal Of Molecular Medicine, Vol: 26 Pages: S68-S68 Supplement: 1 Meeting Abstract: 355, 2010
  17. Antiproliferative activity of 18 selective Malaysian plants, 23rd Scientific Meeting of the Malaysian Society of Pharmacology and Physiology, 12 May 2009 to 13 May 2009, MSPP
  18. Shu M.H., Wong P.F., Cheong W.F., Chan K.L. and AbuBakar S. 2009. Bioactive Compound of Eurycoma longifolia (Jack) Modulates Important Signaling Molecules of Lung Cancer Cells. Proceeding - 3rd Regional Conference On Molecular Medicine, Page 120
  19. Wong P.F., Chan K.L. and AbuBakar S. 2009. Transcriptional Changes in LNCAP Prostate Cancer Cells Treated with an Enriched Fraction of Eurycoma longifolia (Jack). Proceeding - 3rd Regional Conference On Molecular Medicine, Page 126
  20. Wong PF and AbuBakar S, Dengue in Malaysia , 2008, 2nd International Conference on Dengue and Dengue Haemorrhagic Fever, Phuket, Thailand, pg. 274,

RESEARCH PROJECT

International
  1. 2020 - 2024, International Funding
    Development Of A Severe Dengue Diagnostic Kit ( Co-Researcher)
  2. 2015 - 2016, International Funding
    Death and Disability- the Vulnerability of Older Malaysians to Urbanization and Climate Change (IF017- 2015) ( Consultant)
  3. 2014 - 2015, International Funding
    Strengthening Biorisk Management in BSL2 Laboratory ( Principal Investigator(PI))

CONSULTANCY PROJECT

  • Animal Welfare Assessment, Indonesia for Paasp Gmbh, PAASP GmBH, Project Leader/Lead Consultant
    21 Oct 2023 - 23 Oct 2023 (International)
  • Site Inspection Japan for Aaalac International Accreditation, AAALAC International, Project Leader/Lead Consultant
    10 Jul 2023 - 14 Jul 2023 (International)
  • Site Inspection, Singapore for Aaalac International Accreditation, AAALAC International, Project Leader/Lead Consultant
    27 Feb 2023 - 03 Mar 2023 (International)
  • Responsible Care and Use of Laboratory Animal Course, Fom, University of Malaya
    01 Feb 2019 - 01 Feb 2019 (National)
  • Prescribing Skills Training Workshop, Fom, 28 February and 25 April 2019, Faculty of Medicine, UM
    01 Feb 2019 - 01 Feb 2019 (National)
  • Association for Assessment and Accreditation of Laboratory Animal Care International (Aaalac) Accreditation Site Visit to Cambodia, AAALAC International
    01 Feb 2017 - 01 Feb 2017 (International)
  • Association for Assessment and Accreditation of Laboratory Animal Care International Ad-Hoc Consultant, Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International
    01 Feb 2015 - 01 Feb 2017 (International)
  • Association for Assessment and Accreditation of Laboratory Animal Care International (Aaalac) Accreditation Site Visit to Malaysia, AAALAC International
    01 Feb 2016 - 01 Feb 2016 (International)
  • Accreditation for Comet, Institute of Biosciences, University Putra Malaysia, COMeT, Institute of Biosciences, University Putra Malaysia
    01 Jul 2014 - 01 Jul 2015 (National)
  • 45th Malaysian Orthopaedic Association Annual Scientific Meeting, Malaysian Orthopaedic Association
    01 Feb 2015 - 01 Feb 2015 (National)
  • University Malaya - Aurigene Collaboration, Aurigene Discovery Technologies Limited
    01 Feb 2011 - 01 Feb 2015 (International)
  • 44th Malaysian Orthopaedic Association, Malaysian Orthopaedic Association
    01 Feb 2014 - 01 Feb 2014 (National)
  • Editing Your Manuscript for Publication: Workshop for Postgraduate Students, Journal of Health and Translational Medicine (Jummec), 24-25th February 2014 - Technical Advisor, University of Malaya
    01 Feb 2014 - 01 Feb 2014 (National)
  • Cancer Research Journal Club, Nobel Endeavour Training Program, 24th January 2014 - Speaker, Faculty of Medicine, UM
    01 Feb 2014 - 01 Feb 2014 (National)
  • Cellomics High Content Screening (Hcs) User Training, 11-13 Oct 2011, University of Malaya
    01 Feb 2011 - 01 Feb 2011 (National)

PAPER PRESENTED

INVITED SPEAKER
  1. Severe Dengue Biomarkers, Seongnam City Biohealthcare International Conference 2023, Gachon University Biodesign Center GUIP, South Korea (International) (29 Nov 2023 - 01 Dec 2023)
  2. Unravelling the Role of Circulating microRNAs in Endothelial Dysfunction and Acute Coronary Syndrome, Summer Croucher Course, Arterial Ageing: From Mechanisms to Applications, Li Ka Sing Faculty of Medicine, Hong Kong University (International) (14 Aug 2023 - 18 Aug 2023)
  3. Cellular Senescence and SASP, Hallmarks of Cancer Course, Clinical Oncology Unit, Faculty of Medicine , Universiti Malaya (National) (13 Aug 2022 - 14 Aug 2022)
  4. Establishment and Operation of Animal Care and Use Committee and Attaining AAALAC International Accreditation University Experiences, Virtual Training Course in the Ethical Use of Animals for Scientific Purposes, Vietnam One Health University Network (International) (24 Mar 2022 - 25 Mar 2022)
  5. Senotherapeutics for Vascular Ageing, National Cheng Kung University (NCKU) Sustainability Leads Weekly Webinars, NCKU Overseas Hubs (International) (13 Oct 2021 - 13 Oct 2021)
  6. AAALAC International Accreditation for Animal Care and Use Program, IJN-UTM Cardiovascular Engineering Centre Webinar Series, IJN-UTM Cardiovascular Engineering Centre, University of Technology Malaysia (National) (12 Aug 2020 - 12 Aug 2020)
  7. Accurately Diagnose Severe Dengue in Hours, UM Startups 2020 Co-Founder Search Day, University of Malaya Centre of Innovation and Commercialization (UMCIC) (National) (09 Mar 2020 - 09 Mar 2020)
  8. miRNAs in Endothelial Cell Senescence, International Conference for Molecular Biology and Biotechnology in conjunction with the 23rd MSMBB Scientific Meeting , MSMBB and Nara Institute of Science and Technology (NAIST) (International) (09 Mar 2016 - 11 Mar 2016)
  9. AAALAC International Accreditation, Animal Care and Use Symposium, International Islamic University Malaysia (IIUM), Office of the Deputy Rector (Research and Innovation) (National) (14 Dec 2015 - 14 Dec 2015)
  10. Getting AAALAC International Accreditation, Current Issues in Laboratory Animal Care and Use Symposium, UM IACUC (National) (08 Oct 2015 - 08 Oct 2015)
  11. (1) Common IACUC Issues at AAALAC International Site Visits: What have been seen? (2) Laboratory Animal Science - Strength and Need , TALAS International Symposium (The 9th TALAS Annual Training and Workshop), Thai Association for Laboratory Animal Science (International) (09 Sep 2015 - 11 Sep 2015)
  12. Endoplasmic Reticulum Stress in Chondrocyte Senescence and Osteoarthritis, 45th Malaysian Orthopaedics Association Annual Scientific Meeting, Malaysian Orthopaedics Association  (National) (22 May 2015 - 24 May 2015)
  13. Silent Information Regulator 2 Type 1 (SirT1) In Chondrocyte Senescence And Osteoarthritis , 44th Malaysian Orthopaedic Association Annual General Meeting / Annual Scientific Meeting, Malaysian Orthopaedic Association (National) (29 May 2014 - 01 Jun 2014)
  14. Hemophagocytosis-associated markers in severe dengue , LRGS Dengue Colloquium and Workshop 2013, TIDREC (National) (11 Jun 2013 - 12 Jun 2013)
  15. Influence of high intracellular zinc on prostate cancer cells growth and transcriptional responses , The 15th World Congress on Advances in Oncology, 13th International Symposium on Molecular Medicine, Loutraki, Greece, Spandidos Publications, Ltd (International) (07 Oct 2010 - 09 Oct 2010)
ORAL PRESENTER
  1. Expression of Transcription Factors Differs in Synovial Biopsies from Different Knee Injuries, British Association for Surgery of The Knee (BASK) Conference 2022 , BASK (International) (17 May 2022 - 18 May 2022)
  2. Cartilage Fragments & Inflammatory Aggregates in Synovial Intimal & Sub-Intimal Layers Reflect Deteriorating Joint Structures & Function, British Association for Surgery of The Knee (BASK) Conference 2022, BASK (International) (17 May 2022 - 18 May 2022)
  3. Overexpression of miR-107 Inhibits Angiogenesis During Development, 14th International Zebrafish Conference, Suzhou, China, International Zebrafish Society (International) (12 Jun 2019 - 16 Jun 2019)
  4. Dengue Surveillance and Control Initiatives, South East Asia Dengue Summit  (National) (17 Jun 2008)
POSTER PRESENTER
  1. Sirt1-p53 Regulatory Switch: A Potential Modulator of Resistant Cancer Stem Cell Features in HepG2 Tumourspheres under Hypoxic Serum-Free Culture Condition, 28th Biological Sciences Graduate Congress, Universiti Malaya (National) (14 Dec 2023 - 15 Dec 2023)
  2. Systemic Biomarker for Early Diagnosis of Knee OA: A Systematic Review and Meta-Analysis, 52nd Malaysian Orthopaedic Association Annual Scientific Meeting 2023, Malaysian Orthopaedic Association (National) (15 Jun 2023 - 17 Jun 2023)
  3. BMI & Gender Impact Gene Expression in Synovial Tissues from Different Knee Pathologies, British Association for Surgery of The Knee (BASK) Conference 2022 , BASK (International) (17 May 2022 - 18 May 2022)
  4. Differential Gene Expression in Human Synovial Tissue Primary Explant Culture Compared with Whole Synovium, British Association for Surgery of The Knee (BASK) Conference 2022 , BASK (International) (17 May 2022 - 18 May 2022)
  5. The role of miR-134-5p in 7-ketocholesterol-induced human aortic endothelial cell dysfunction, 34th Malaysia Society of Pharmacology and Physiology Scientific Meeting 2021, Monash University Malaysia (National) (15 Jul 2021 - 17 Jul 2021)
  6. Attenuation of endothelial cell senescence via the inhibition of mammalian target of rapamycin (MTOR) involves miR-107 and PTEN, Pharmacology 2018, British Pharmacological Society (International) (18 Dec 2018 - 20 Dec 2018)
  7. miR-107 Regulated Endothelial Replicative Senescence via mTOR Complex 1 , Aging and Mechanism of Aging-Related Disease, Keystone Symposia on Molecular and Cellular Biology (International) (15 May 2017 - 19 May 2017)
  8. Anti-adipogenic effect of a standardized quassinoid-enriched fraction of E. longifolia, 3rd Pan Asian Biomedical Science Conference, National Biomedical Sciences Society (National) (07 Dec 2016 - 08 Dec 2016)
  9. DHODH: A Potential Drug Target In Malignant Melanoma Cells, Malaysian Society for Molecular Biology and Biotechnology 22nd Annual Scientific Meeting. 2015, Malaysian Society for Molecular Biology and Biotechnology (National) (08 Sep 2015 - 09 Sep 2015)
  10. Inhibition of mTOF Complex 1 (mTORCI) Mitigates Replicative Senescence in Endothelial Cells, 21st Annual Malaysian Society for Molecular Biology and Biotechnology Meeting, Monash University Malaysia (National) (01 Oct 2014 - 03 Oct 2014)
  11. Panduratin A Inhibits Angiogenesis by Targeting mTOR Pathway, Pharmacology and Physiology International Scientific Congress, MSPP-VNEM-ASVB-MSH (International) (22 Aug 2014 - 24 Aug 2014)
  12. Standardized-rich quassinoids Eurycoma longifolia fraction suppresses prostate cancer progression and bone marrow colony formation in vivo , Pharmacology and Physiology International Scientific Congress, MSPP-VNEM-ASVB-MSH (International) (22 Aug 2014 - 24 Aug 2014)
  13. Paeonol Protects Endothelial Cells from Stress Induced Premature Senescence by Activating Sirt1 , Pharmacology and Physiology International Scientific Congress (International) (22 Aug 2014 - 24 Aug 2014)
  14. Dengue Virus Infection Induces Endothelial Senescence, 16th International Congress on Infectious Diseases (ICID), South Africa (International) (02 Apr 2014 - 05 Apr 2014)
  15. Paeonol Protects Endothelial Cells Against H2O2-Induced Senescence, International Conference on Natural Products and Health 2013 (NPH2013), School of Biological Sciences (SBS), Nanyang Technological University (NTU), Singapore, on 5-7 Sep, 2013, School of Biological Sciences (SBS), Nanyang Technological University (NTU), Singapore (International) (05 Sep 2013 - 07 Sep 2013)
  16. Anti-proliferative potentials of standardized quassinoid-rich Eurycoma Iongifolia extract on prostate cancer cells. , International Conference on Natural Products and Health 2013 (NPH2013), Nanyang Technological University (NTU), Singapore (International) (05 Sep 2013 - 07 Sep 2013)
  17. microRNAs Targeting Histone Deacetylase in Cellular Senescence of Endothelial Cells, RNAi and miRNA Europe qPCR Europe Epigenetics Europe, RNAi and miRNA Europe qPCR Europe Epigenetics Europe (International) (08 Sep 2011 - 09 Sep 2011)
  18. Involvement of Nuclear Factor-kappa B Signaling in the Induction of Apoptosis and Inhibition of Human Prostate Cancer PC3 Cell Invasion by Alpha-tomatine, Beatson International Cancer Conference, Cancer Research UK (International) (03 Jul 2011 - 06 Jul 2011)
  19. Evaluation of anti-cancer effect of alpha-tomatine on PC-3 human prostate cancer cells by cell impedance and high content screening assay, 35th Annual Conference of the Malaysian Society for Biochemistry & Molecular Biology (National) (27 Jul 2010 - 28 Jul 2010)
  20. Direct Binding Of Gangliosides To Helicobacter Pylori Vacuolating Cytotoxin (Vaca) Neutralizes Its Toxin Activity, 3rd Congress of European Microbiologists, 3rd Congress of European Microbiologists, FEMS (International) (28 Jun 2009 - 02 Jul 2009)
  21. Antiproliferative activity of 18 selective Malaysian plants, 23rd Scientific Meeting of the Malaysian Society of Pharmacology and Physiology (National) (12 May 2009 - 13 May 2009)
  22. Transcriptional changes in LNCaP prostate cancer cells treated with an enriched fraction of Eurycoma longifolia (Jack), 3rd Regional Conference of Molecular Medicine, UKM (International) (02 May 2009 - 04 May 2009)
  23. Bioactive compound of Eurycoma longifolia (Jack) modulates important signaling molecules of lung cancer cells, 3rd Regional Conference of Molecular Medicine, UKM (International) (02 May 2009 - 04 May 2009)
  24. Metastatic burden of human myeloma labelled with luciferase reporter gene in CD122+ cells-depleted NOD/SCID recipients. , 38th Annual Scientific Meeting, Australasian Society for Immunology , Australasian Society for Immunology (International) (07 Dec 2008 - 11 Dec 2008)
  25. Dengue in Malaysia (2002-2005), Second International Conference on Dengue and Dengue Haemorrhagic Fever, Bureau of Vector Borne Diseases, Department of Disease Control, Ministry of Public Health, Thailand (International) (17 Oct 2008)
  26. Prolonged supplementation of prostate cancer cells with zinc induced cell growth inhibition. , The 15th Scientific Meeting of Malaysian Society for Molecular Biology and Biotechnology, Society for Molecular Biology and Biotechnology (National) (04 Apr 2005 - 05 Apr 2005)
  27. Proteomics Investigation of Long-term Effect of Zinc on Prostate Cancer Cells, Proceedings of the UMS Biotechnology Symposium II Signal Transduction: Mechanisms and Applications, UMS (International) (03 Dec 2003 - 05 Dec 2003)
  28. Combinatorial Application of Proteomics and Bioinformatics in Protein Mapping of the Seaweed, Gracilaria changii, 2nd International Conference on Bioinformatics,  (International) (08 Sep 2003 - 10 Sep 2003)
  29. The determination of the jackfruit (Artocarpus heterophylus Lam) seed maturation proteins using the proteomic and bioinformatics approaches., 2nd International Conference on Bioinformatics,  (International) (08 Sep 2003 - 10 Sep 2003)
  30. Protein Profiles Of The Agarophyte, Gracilaria changii., The 13th Scientific Meeting of Malaysian Society for Molecular Biology and Biotechnology, , Malaysian Society for Molecular Biology and Biotechnology (National) (19 May 2003 - 21 May 2003)
  31. Construction and Characterization of A Japanese Encephalitis/Dengue 2 Chimeric Virus. , XIIth International Congress of Virology,  (International) (27 Jul 2002 - 01 Aug 2002)
  32. Two-Dimensional Electrophoresis Analysis Of Hevea Brasiliensis Seed Protein Profiles And Identification Of Germination Associated-Protein By MALDI-TOF. , The 12th Scientific Meeting of Malaysian Society for Molecular Biology and Biotechnology, Malaysian Society for Molecular Biology and Biotechnology (National) (22 May 2002 - 24 May 2002)
PRESENTER
  1. Emergency Preparedness and Disaster Plan for Animal Facilties, Emergency Preparedness and Disaster Planning, Animal Experimental Unit, Faculty of Medicine (University) (11 Apr 2016 - 11 Apr 2016)
KEYNOTE SPEAKER
  1. Harnessing Novel Therapeutics Through Marine Pharmacology, The 5th Biological Security and Sustainability Seminar (BIOSES) 2024, Universiti Malaysia Terengganu (National) (28 Aug 2024 - 29 Aug 2024)
OTHERS
  1. MicroRNA signature of pulmonary microvascular hyperpermeability in senescent pulmonary endothelial cells, International Student Congress of (bio)Medical Science (ISCOMS), University Medical Centre Groningen, Netherland (International) (05 Jun 2012 - 08 Jun 2012)

ACADEMIC/PROF. SERVICES

Evaluation
  1. (2024) External Examiner of Phd Proposal Defence (Regenerative Medicine), University, (External Examiner)
  2. (2024) Malaysia Toray Science Foundation (Mtsf) - Science & Technology Research Grant Reviewer, University, (Reviewer)
  3. (2024) External Examiner of Phd Proposal Defence (Anatomy), University, (External Examiner)
  4. (2024) Fundamental Research Grant (Frgs) Phase 1/2024, University, (Reviewer)
  5. (2023) Assessor for Universiti Malaya Research Excellence Grant 2023, University, (Reviewer)
  6. (2023) Fundamental Research Grant (Frgs) Phase 1/2023, University, (Reviewer)
  7. (2022) Thesis Defence Seminar (Circulating Mirnas and Genetic Determinants in Gestational Diabetes), University, (Internal Evaluator)
  8. (2022) Mmed Sc (Osteoarthritis), University, (External Assessor)
  9. (2022) Peer Review for Collaborative Research Programme (Crp)-Icgeb Research Grant, University, (Internal Evaluator)
  10. (2022) Phd Thesis (Anti-Viral Mechanism), University, (Internal Examiner)
  11. (2022) Phd Thesis (Cancer Cell Signaling Mechanisms), National, (External Examiner)
  12. (2022) Mmed Sc Proposal (Vascular Biology), University, (Internal Assessor)
  13. (2021) Impact-Oriented Interdisciplinary Research Grant (Iirg) Cycle 4/2021, University, (Internal Evaluator)
  14. (2021) Phd Thesis (Cancer Stem Cell), University, (Internal Examiner)
  15. (2021) MBBS Entrance Exam, 2021/2022, University, (Internal Assessor)
  16. (2021) Poster Judge, 4th International Conference On Molecular Biology & Biotechnology (Icmbb2021), International, (External Assessor)
  17. (2021) Ageing Research Reviews, International, (Reviewer)
  18. (2021) Umsc Ca.R.E Fund (Research Grant) Cycle 1/2021 Project Umsc2021 (63), University, (Reviewer)
  19. (2021) Fundamental Research Grant (Frgs) Phase Phase 1/2023, University, (Reviewer)
  20. (2021) Frontiers in Pharmacology, International, (Reviewer)
  21. (2020) Research Project Peer Review for Joint Research Compliance Office (JRCO), Imperial College London and Imperial College Healthcare NHS, (Reviewer)
  22. (2019) Asia Pacific Journal of Molecular Biology and Biotechnology, Reviewer , (Reviewer)
  23. (2019) Rejuvenation Research, Reviewer , (Reviewer)
  24. (2019) Journal of Cellular and Molecular Medicine, Reviewer, (Reviewer)
  25. (2018) Cell Physiol Biochem, Revieiwer, (Reviewer)
  26. (2018) European Journal of Pharmacology, Reviewer, (Reviewer)
  27. (2018) Master of Science, USM (Ageing), External Examiner , (External Examiner)
  28. (2018) PhD Thesis, UKM (Molecular Pharmacology), External Examiner , (External Examiner)
  29. (2018) Masters Thesis, USM (Molecular Pharmacology), External Examiner , (External Examiner)
  30. (2018) MTEB 2180 Research Project In Biomedical Sciences, Examiner , (External Examiner)
  31. (2017) Biomedicine and Pharmacotherapy - Reviewer, (Reviewer)
  32. (2017) MTEB 2180 Research Project In Biomedical Sciences, Examiner , (Internal Examiner)
  33. (2016) PlosOne - Reviewer, (Reviewer)
  34. (2016) Journal of Medicinal Plant - Reviewer, (Reviewer)
  35. (2016) Journal of Free Radical Research - Reviewer, (Reviewer)
  36. (2016) Phytotherapy Research - Reviewer , (Reviewer)
  37. (2015) The Malaysian Journal of Pathology, Reviewer, (Reviewer)
  38. (2015) Immunopharmacology and Immunotoxicology - Reviewer, (Reviewer)
  39. (2015) Therapeutics and Clinical Risk Management, Reviewer , (Reviewer)
  40. (2015) Journal of Cellular Biochemistry - Reviewer, (Reviewer)
  41. (2015) Scientific Reports, Nature Publishing Group, Reviewer, (Reviewer)
  42. (2015) Expert Opinion on Drug Discovery - Reviewer, (Reviewer)
  43. (2015) UCSI External Assessor Panel , (EXTERNAL ASSESSOR)
  44. (2014) International Journal of Nanomedicine - Reviewer , (Reviewer)
  45. (2013) Environmental Toxicology and Pharmacology - Reviewer , (Reviewer)
  46. (2012) Pharmaceutical Biology - Reviewer , (Reviewer)
  47. (2012) MTEB 2180 Research Project in Biomedical Sciences, Examiner , (Internal Examiner)
  48. (2011) MTEB 2180 Research Project in Biomedical Sciences, Examiner , (Internal Examiner)
  49. (2010) MTEB 2180 Research Project in Biomedical Sciences, Examiner, (Internal Examiner)
  50. (2009) Cancer Cell International Journal - Reviewer, (Reviewer)
Contribution to external organisation
  1. (2023) Association for Assessment and Accreditation of Laboratory Animal Care International (Aaalac) Accreditation Site Visit to Ehime, Japan, University, (Auditor)
  2. (2023) Association for Assessment and Accreditation of Laboratory Animal Care International (Aaalac) Accreditation Site Visit to Shizuoka, Japan, International, (Auditor)
  3. (2020) Research Collaboration, Associate Prof Hsien-Tai Chiu, National Cheng Kung University, Taiwan, International
  4. (2019) Research Collaboration, Dr. Karyn Morrissey, University of Exeter, International
  5. (2019) Research Collaboration, Professor Simon Frostick, University of Liverpool, International
  6. (2019) Research Collaboration, Assoc Prof Vikneswaran Murugaiyah and Prof. Chan Kit Lam, University of Science Malaysia (USM), National
  7. (2019) FRGS Phase 1/2019 Reviewer Panel, University of Malaya
  8. (2018) Research Collaboration, Professor Ming Yang, Tokyo Metropolitan University, International
  9. (2018) PILL-1 Training Workshop, FOM, 22 Feb and 19 April 2018, University of Malaya
  10. (2018) Screening Interview of Academic Staff, TIDREC
  11. (2018) FRGS Phase 1/2018 Reviewer Panel, PPGP
  12. (2018) Responsible Care and Use of Laboratory Animal Course, FOM, 10 July 2018, University of Malaya
  13. (2018) FOM Early Career Mentorship Program, Faculty of Medicine, UM
  14. (2018) Restructuring Panel Member for Central Research Laboratories, Faculty of Medicine, UM
  15. (2016) Committee Member for Infrastructure Development, Faculty of Medicine
  16. (2015) Joint PhD Program between University of Liverpool (UoL) and University of Malaya (UM), UoL and UM, International
  17. (2015) PPP Grant Evaluator, Pharmacology
  18. (2014) Sabbatical Laboratory Attachment, Prof. Joao Pedro de Magalhaes, Integrative Genomics of Ageing Group, Institute of Integrative Biology, International
  19. (2014) Selection Committee for the Management and Professional Group (Non-Academic) - Veterinary Officer Grade 41, University of Malaya
  20. (2013) Research Collaboration, Dr. Kavitha Nellore, Aurigene Discovery Technologies Limited, India, International
  21. (2013) Research Collaboration, Associate Prof. JD Hooper, Mater Medical Research Institute, Translational Research Institute, Queensland, Australia, International
  22. (2013) Research Collaboration, Professor PM Vanhoutte, Department of Pharmacology and Pharmacy Li Ka Shing Faculty of Medicine, Hong Kong University, International
  23. (2013) Research Collaboration, Dr Akihiro Wada, Department of Bacteriology,Institute of Tropical Medicine,Nagasaki University,Nagasaki, Japan, International
  24. (2012) Subcommittee on Ethical Use of Animals in Laboratory Experiments, Ministry of Science, Technology and Innovations
Contribution to event
  1. (2023) Invited Speaker, Seongnam Biohealthcare International Conference 2023, International, (Panelist/Moderator)

SUPERVISION

Postgraduate Student
PhD/ Doctoral
  1. (2024) INVESTIGATION OF THE ENDOPLASMIC RETICULUM (ER) STRESS-STING CROSSTALK DRIVING SYNOVIAL INFLAMMATION IN OSTEOARTHRITIS, SOH LI JEN
  2. (2024) DEVELOPMENT OF A NOVEL EXOSOME-BASED DENGUE VACCINE FOR INDUCING PROTECTIVE IMMUNITY AGAINST ALL FOUR DENGUE VIRUS SEROTYPES, CHEAH ZIYIN
  3. (2024) Endoplasmic Reticulum Stress and Unfolded Protein Response Pathway Activation in the Synovium of Knee Osteoarthritis Patients, LEE SIAM YEE
  4. (2024) Regulatory mechanism of HIFs-SIRT1-p53-miRNA axis in hepatocellular carcinoma tumourspheres cultured under hypoxic culture condition, SAKUNIE A/P SAWAI
  5. (2023) Osteoarthritis stage diagnostic with deep learning approach and correlation to the level of biomarkers of the disease, MARGARITA SHISHKINA
  6. (2019) THE INHIBITION OF DIHYDROORATE DEHYDROGENASE (DHODH) AS AN ANTI-PROLIFERATIVE STRATEGY TO SUPPRESS MELANOMA GOWTH, MATHURA SUBANGARI A/P DORASAMY
  7. (2017) Mammalian and zebrafish target of rapamycin-associated micrornas in endothelial cell senescence, KHOR ENG SOON
  8. (2014) Anti-Cancer and Anti-Angiogenic Mechanisms of Panduratin A Isolated from Boesenbergia Rotunda, LAI SIEW LI
  9. (2012) IN VITRO AND IN VIVO PRO-APOPTOTIC AND CHEMOSENSITIZING EFFECTS OF ALPHA-TOMATINE ON HUMAN PROSTATE ADENOCARCINOMA, LEE SUI TING
Master
  1. (2024) INVESTIGATION OF THE SENOLYTIC EFFECT OF FISETIN ON DENGUE VIRUS REPLICATION IN ENDOTHELIAL CELLS, YAP YI JING
  2. (2024) Targeting Vascular Aging with Senotherapeutics, TIEN XIN YI
  3. (2024) ROLE OF MICRORNA-217/FOXO3A AXIS IN ENDOTHELIAL CELL SENESCENCE, KHOR YI SHENG
  4. (2024) DEVELOPMENT OF EXOSOME-BASED PEPTIDE VACCINE (E3P-EXO) FOR DENGUE VIRUS INFECTION, HARIZ BIN MOHAMAD SALLEH
  5. (2022) Aphrodisiac activity of Eurycoma longifolia Jack extract: Isolation and characterization of its phytochemical constituents, Ang Jing Jie (Taylor's University)
  6. (2019) Investigating the Effects of Eurycoma Longifolia on Testosterone-Induced Benign Prostatic Hyperplasia in Rats and the Mechanisms Involved, Liew Wai Lam (Universiti Sains Malaysia (USM))
  7. (2017) In Vitro & In Vivo Anti-Adipogenic Effects of a Standardized Quassinoid Composition from Eurycoma Longifolia., DHARVIND A/L BALAN
  8. (2014) P53-Mdm2 Interaction Targeted Therapy By Nutlin-3 On Nasopharyngeal Carcinoma Cells, VOON YEE LIN
  9. (2013) Anti-Prostate Tumor and Myeloprotective Activities of Quassinoids from Eurycoma longifolia, TONG KIND LENG
  10. (2013) THE CYTOPROTECTIVE EFFECT OF PAEONOL ON OXIDATIVE STRESS-INDUCED PREMATURE SENESCENCE IN ENDOTHELIAL CELLS, JULIANA BINTI JAMAL
Under Graduate Students
  1. (2017) MTEB 2180 Research Project In Biomedical Sciences - A Study on the Migration Potential of Human Synovial Fibroblasts Derived from Osteoarthritic Patients - Lee Siam Yee
  2. (2015) MTEB 2180 Research Project In Biomedical Sciences - The Role of hsa-miR-20b in TNF-alpha Induced Premature Senescence in Endothelial Cells - Yeap Chia Earn
  3. (2014) MTEB 2180 Research Project In Biomedical Sciences - Investigation of the Mechanism of E. longifolia-induced Growth Inhibition of Prostate Cancer Cells - Tong King Leng

TEACHING

Master
  1. (2023) NA - Postgraduate Basic/Clinical Science (Medicine) (Drugs Interaction)
  2. (2023) MOB7007 - Advance Tools in Regenerative Medicine
  3. (2022) NA - Postgraduate Basic/Clinical Science (Medicine) (Drugs Interaction)
  4. (2022) MOB7007 - Advance Tools in Regenerative Medicine
  5. (2020) PG - Postgraduate Basic/Clinical Science for Medicine
  6. (2019) PG - Postgraduate Basic/Clinical Science for Medicine
  7. (2018) PG - Postgraduate Basic/Clinical Science for Medicine
  8. (2017) PG - Postgraduate Basic/Clinical Science for Dentistry
  9. (2017) PG - Postgraduate Basic/Clinical Science for Medicine
Bachelor
  1. (2023) NA - Pbl Stage 1 Musculoskeletal
  2. (2023) NA - Pbl Stage 2 Hematology
  3. (2023) NA - Prescribing Skills
  4. (2023) NA - Ummp Stage 1 Pharmacology
  5. (2023) NA - Ummp Stage 2 Pharmacology
  6. (2023) MIC3010 - Advances in Medical Pharmacology
  7. (2023) MIX3003 - Drugs: from Target to Market
  8. (2023) DIA2006 - Pharmacology
  9. (2023) MID1009 - Pharmacology in Nursing
  10. (2023) MIC2004 - Principles in Pharmacology and Toxicology
  11. (2022) NA - Ummp Stage 1 Pharmacology
  12. (2022) NA - Ummp Stage 2 Pharmacology
  13. (2022) MIC3010 - Advances in Medical Pharmacology
  14. (2022) MIX3003 - Drugs: from Target to Market
  15. (2022) DIA2006 - Pharmacology
  16. (2022) MID1009 - Pharmacology in Nursing
  17. (2021) MIC3010 - Advances in Medical Pharmacology
  18. (2021) MID1009 - Pharmacology in Nursing
  19. (2021) MIX3003 - Drugs from Target to Market
  20. (2020) DIA2006 - Pharmacology
  21. (2020) UMMP - Ummp Pharmacology
  22. (2019) DIA2006 - Pharmacology
  23. (2019) MIX3003 - Drugs: from Target to Market
  24. (2019) UMMP - Ummp Pharmacology
  25. (2018) MIC2004 - Principles in Pharmacology and Toxicology
  26. (2018) UMMP - Ummp Pharmacology
  27. (2017) MBEB2105 - General Principles in Pharmacology and Toxicology
  28. (2017) MID1009 - Pharmacology in Nursing
  29. (2017) UMMP - Ummp Pharmacology
  30. (2016) MBEB2105 - General Principles in Pharmacology and Toxicology
  31. (2016) MBEB2105 - General Principles in Pharmacology and Toxicology
  32. (2016) MIC2013 - Laboratory Animal Science
  33. (2016) MTEJ2102 - Clinical Sciences
  34. (2016) MWEF2103 - Central Nervous System & Therapy
  35. (2016) UMMP - Ummp Pharmacology
  36. (2015) DNED2101 - Pharmacology
  37. (2014) Ummp Pharmacology Foundation Block
Others
  1. () MDC1009 - Diploma in Medical Lab Techonology

PATENT/IPR

  • MS ISO 13485 Certified Severe Dengue Diagnostic Kit
    MS ISO Certification (National)
  • Animal Experimental Unit Service Pod
    In Vivo Testing Services (National)
  • Responsible Care and Use of Laboratory Animal Course (RCULAC) Video
    Copyright (National)
  • Biomarker for Severe Dengue
    Patent (National)
  • A Method to i) Inhibit The Lung Cancer Cell Proliferation and Tumor Growth and ii) Suppression of Expresion of Lung Cancer Cell Growth Markers Using Eurycomanone, A Quasinoid From Eurycoma Longifolia Jack
    Patent (National)

SOCIAL RESPONSIBILITY ACTIVITIES

  • Invited Speaker of Bfm Health and Living Interview for Humans of Healthcare Series: The Pharmacologist, (13 Feb 2024 - 13 Feb 2024) (National)
  • Invited Speaker of Bfm Radio Station Health &Amp; Living Interview for Brain Waves Series: Zombie (Cells) in Your Brain and Body, (22 Mar 2023 - 22 Mar 2023) (National)
  • International Day of Older Persons 2021. "Healthy Ageing With Less Sugar and Fat" (Invited Speaker), (14 Oct 2021 - 14 Oct 2021) (National)
  • Sin Chew Daily Newspaper Feature -【鼠年鼠事之二】药物测试先锋，解开疾病的奥秘 Year of The Rat: Pioneer in Drug Testing and Unlocking The Mystery of Disease, (23 Jan 2020 - 23 Jan 2020)
  • Mykidney Fun Run 2019, “Be Someone’S Reason to Be Alive”, Ceo@Faculty Programme 2.0, Ministry of Education Malaysia, (13 Apr 2019 - 13 Apr 2019)
  • Let'S Go to Mummies Lab - Sekolah Kebangsaan Melayu Raya, Segamat, Johor, (13 Feb 2018 - 13 Feb 2018)
  • Keeping The Country Healthy, Postgraduate Column, Star Special, Thestar, (16 May 2017 - 16 May 2017)
  • Tv Documentary (Majalah Tiga, Tv3) - Tikus Bukan Sekadar Haiwan Perosak (Rodents Are Not Just Pests), (28 Mar 2016 - 28 Mar 2016)