Curriculum Vitae

DR. WAN IZLINA BINTI WAN IBRAHIM

Senior Lecturer
  • Department of Oral and Craniofacial Sciences
    Faculty of Dentistry
  • 0379677403

AREAS OF EXPERTISE


  • TRADITIONAL MEDICINE AND NATURAL PRODUCTS
    Free radical biochemistry & DNA damage
  • GEL- & NON-GEL-BASED PROTEOMICS, LIQUID CHROMATOGRAPHY & MASS SPECTROMETRY
  • PROTEINS
    Proteomics & glycoproteomics - cancer, disease biomarkers, human and mammalian milk

ACADEMIC QUALIFICATION


  • PhD, (Medical Science)
    Universiti Malaya (UM)
  • MMedSc, (Medical Science)
    Universiti Malaya (UM)
  • BBioMedSc (Hons), (Sains Bioperubatan)
    Universiti Malaya (UM)

MEMBERSHIPS


  • MALAYSIAN SOCIETY OF ORAL MICROBIOLOGIST & ORAL IMMUNOLOGIST, MEMBER
    Since 2020 (National)
  • ORAL CANCER RESEARCH & COORDINATING CENTRE (OCRCC) - RESEARCH MEMBER, MEMBER
    2021 to 2023 (University)
  • MALAYSIAN PROTEOMICS SOCIETY (MAPS), MEMBER
    2021 to 2022 (National)

AWARD AND STEWARDSHIP


  • EXCELLENCE SERVICE AWARD
    University of Malaya, 2022 (University)
  • International Learning Improvement & Teaching Enhancement Conference (LITEC) 2021
    Universiti Malaya, 2021 (University)
  • CERTIFICATE OF EXCELLENT SERVICE
    University of Malaya, 2021 (University)

PUBLICATIONS


Article in Journal
WoS
  1. Jaulin, Nundisa; Idrus, Ruszymah Hj; Saim, Aminuddin; Wan-Ibrahim, Wan Izlina; Abdul-Rahman, Puteri Shafinaz; Lokanathan, Yogeswaran (2022). Airway Fibroblast Secretory Products Enhance Cell Migration, CURRENT PROTEOMICS. 19(2), 182-195. doi:10.2174/1570164618666210823094105
  2. Kwan, S. H., Wan-Ibrahim, W. I., Juvarajah, T., Fung, S. Y., & Abdul-Rahman, P. S. (2021). Isolation and identification of O- and N-linked glycoproteins in milk from different mammalian species and their roles in biological pathways which support infant growth. Electrophoresis, 42(3), 233-244. doi: 10.1002/elps.202000142
  3. Amran, N., Wan-Ibrahim, W. I., Rashid, N. N., Ali, J. M., & Abdul-Rahman, P. S. (2020). Tualang honey inhibits cell proliferation and promotes apoptosis of human lung adenocarcinoma cells via apoptosis signaling pathway. European Journal of Integrative Medicine, 37, 8. doi: 10.1016/j.eujim.2020.101149
  4. Juvarajah, T., Wan-Ibrahim, W. I., Ashrafzadeh, A., Othman, S., Hashim, O. H., Fung, S. Y., Abdul-Rahman, P. S. Human Milk Fat Globule Membrane Contains Hundreds of Abundantly Expressed and Nutritionally Beneficial Proteins That Are Generally Lacking in Caprine Milk. Breastfeeding Medicine, 7. doi:10.1089/bfm.2018.0057
  5. Wan-Ibrahim, Wan Izlina; Ashrafzadeh, Ali; Singh, Vivek Ajit; Hashim, Onn Haji; Abdul-Rahman, Puteri Shafinaz (2016). Contrasting increased levels of serum amyloid A in patients with three different bone sarcomas: An indicator of tumor malignancy?, ELECTROPHORESIS. 37(17-18), 2328-2337. doi:10.1002/elps.201500522
Scopus
  1. Wan-Ibrahim W.I., Radzi Z., Yahya N.A. (2023). Trace Elements in Oral Immunology, Immunology for Dentistry. , 61-78. doi:10.1002/9781119893035.ch6
Others
  1. Wan-Ibrahim, W.I., Singh, V.A., Hashim, O.H. & Abdul-Rahman, P.S. (2015). Biomarkers for Bone Tumours: Discovery from Genomics and Proteomics Studies and Their Challenges. Mol Med, 21, 861-72.
  2. Pang, W.W., Abdul-Rahman, P.S., Wan-Ibrahim, W.I. & Hashim, O.H. (2010). Can the acute-phase reactant proteins be used as cancer biomarkers? Int J Biol Markers, 25(1), 1-11.
  3. Wan-Ibrahim, W.I., Sidik, K. & Kuppusamy, U.R. (2010). A high antioxidant level in edible plants is associated with genotoxic properties. Food Chem, 122, 1139-44.
  4. Gabrielsen, M., Riboldi-Tunnicliffe, A., Abdul-Rahman, P.S., Mohamed, E., Wan-Ibrahim, W.I., Hashim, O.H., Isaacs, N.W. & Cogdell, R.J. (2009). Crystallization and preliminary structural studies of champedak galactose-binding lectin. Acta Crystallogr Sect F Struct Biol Cryst Commun, 65(Pt 9), 895-7.
Article in Proceeding
  1. 2-Dimensional Gel Electrophoresis Analysis of Soluble Milk Serum Proteins. Shin Yee Fung, Thaneswari Juvarajah, Ali Ashrafzadeh, Wan Izlina Wan-Ibrahim, Onn Haji Hashim, Shatrah Othman and Puteri Shafinaz Abdul-Rahman. 2nd Regional Conference on Breastfeeding.27-29 August 2019, Cyberjaya, Malaysia
  2. Discovery of Proteins Available in Human Milk that Potentially Reduce the Risk of Attention Deficit/Hyperactivity Disorder (ADHD) by using Proteomics Approach. Soon Hong Kwan, Wan Izlina Wan-Ibrahim & Puteri Shafinaz Abdul-Rahman. 2nd Regional Conference on Breastfeeding.27-29 August 2019, Cyberjaya, Malaysia
Other Publications
  1. Nor Ahmad Rajkumar NF, Safii SH, Wan-Ibrahim WI & Abdul Razak F. (2021). P59: Antioxidant Properties of Psidium guajava, Nigella sativa, Azadirachta indica and Averrhoa bilimbi Plant Extracts. 22nd Annual General Meeting IADR Malaysian Section. Programme eBook. - Meeting Abstract

RESEARCH PROJECT


National
  1. 2020 - 2024, Fundamental Research Grant Scheme (FRGS)
    Circadian Rhythmicity In Saliva And Milk: Elucidating Its Roles In Maintaining Oral Health In Pregnant Women, Nursing Mothers And Infants ( Principal Investigator(PI))
  2. 2021 - 2024, Fundamental Research Grant Scheme (FRGS)
    Proteomics Approach To Understand Antimicrobial Mechanism Of ?-mangostin As Disinfectant For Dental Impressions ( Co-Researcher)
  3. 2019 - 2023, Fundamental Research Grant Scheme (FRGS)
    Bioactivities Of Nigella Sativa In Oral Tissue Repair: Evaluating Their Intracellular And Extracellular Responses In Healing ( Co-Researcher)
  4. 2019 - 2022, Others MOHE - Top 100 (IIRG)-HWB
    Expression Of Inflammatory And Healing Biomarkers Following Use Of Amp As An Adjunct To Scaling And Rsd In The Treatment Of Chronic Periodontitis ( Co-Researcher)
  5. 2019 - 2022, Others MOHE - Top 100 (IIRG)-SAH
    Investigating The Dynamic Changes In Human Milk Protein Composition Of Malaysian Mothers At Different Stages Of Lactation ( Principal Investigator(PI))
  6. 2021 - 2022, Bantuan Khas Penyelidikan (BKP Special)
    Circadian Rhythmicities In Breast Milk Of Nursing Mother: A Metabolomic Profiling Study ( Co-Researcher)
  7. 2017 - 2020, UM Grant - Frontier Research Grant
    Unravelling The Molecular Mechanisms Of Diffrentially Expressed Proteins Following Supplementation Of Tocotrienols In A Syngeneic Mouse Breast Cancer Model Using Quantitative Proetomics Profiling Strategies ( Co-Researcher)

PAPER PRESENTED


INVITED SPEAKER
  1. How to use Google Forms to create and grade online exam papers for Year 4 BDS Professional Exam 2019/2020, Online Teaching and Learning, Dept. Community Oral Health & Clinical Prevention, Faculty of Dentistry (Others) (13 Jul 2020 - 13 Aug 2020)

ACADEMIC/PROF. SERVICES


Evaluation
  1. (2022) Timbalan Ketua Tahun Satu, Program Sarjana Muda Pergigian dan Pembedahan, University, (Reviewer)
  2. (2022) Penyelaras Kelas Pengajaran dan Pembelajaran Online Tahun Satu Bds, University, (Reviewer)
  3. (2021) Admission Interview - Bachelor of Dental Surgery (Bds) for Academic Session 2021/2022, University, (Internal Evaluator)
  4. (2021) Reviewed One Article Submitted to F1000research, International, (Reviewer)
  5. (2021) Deputy Head, Integrated Module Bds 2020/2021 (Dental Anomalies), University, (Reviewer)
  6. (2021) Assessor for Bachelor of Biomedical Science Final Year Project Oral Presentation - Ch ng Hui Zhen (Relationship between Antioxidant and Anticancer Properties of Phloroglucinol in Colorectal cancer cells, Caco-2)
  7. (2021) Reviewed one article submitted to F1000Research, (Reviewer)
  8. (2021) Reviewed one article submitted to Asian Food Science Journal, (Reviewer)
  9. (2021) Reviewed one article submitted to Archives Of Orofacial Sciences, (Reviewer)
  10. (2020) Reviewed one article submitted to Microbiology Insights, (Reviewer)
  11. (2020) Internal Examiner Master in Medical Science (Regenerative Medicine) - Nik Syazana Isyan Saffery (Protein profiling and spatial imaging of osteoarthritis knee derived synovial membrane) , (Internal Examiner)
  12. (2020) Reviewed one article submitted to Journal of Health and Translational Medicine, (Reviewer)
  13. (2020) Panel for Candidature Defence (Doctoral Thesis) - Jazli Aziz (Rheumatoid arthritis linked to periodontitis: interplay between oral bacteriophages and nutritional immunity) , (Internal Examiner)
  14. (2020) Examiner for Bachelor of Biomedical Science Final Year Project - Sitti Norfazilah Jainuddin (Study on the gut bacteria and fungus in colorectal cancer and mentally ill patients) , (Internal Examiner)
  15. (2020) Panel for Thesis Seminar (Doctoral Thesis)- Wong Yin Ling (Identification of Potential Biomarkers in Oral Squamous Cell Carcinoma Using Integrated Proteomics and Glycoproteomics Analyses)
  16. (2020) Reviewed one article submitted to Archives Of Orofacial Sciences , (Reviewer)
  17. (2019) Internal Examiner Master of Dental Science - Nursolehah Shahruddin (Detection of Subgingival Periodonto-pathogens and Inflammatory Cytokines in Adults with Chronic Periodontitis) , (Internal Examiner)
  18. (2019) Assessor for Elective Project Report, Short and long-term career aspirations, and future dental specialty preferences among recent graduates of University of Malaya, Bachelor of Dental Surgery 2018/2019 , (Internal Examiner)
  19. (2019) Internal Examiner Master of Medical Science - Sarmini a/p Munisamy (Elucidating the roles of T-helper and T-regulatory cells in sarcoma patient) , (Internal Examiner)
  20. (2019) Panel for Proposal Defence (Master in Medical Science - Regenerative Medicine) - Nik Syazana Isyan Saffery (Protein in profiling of synovial membrane from osteoarthritis patients) , (Internal Examiner)
  21. (2019) Panel for Candidature Defence (Master in Medical Science - Regenerative Medicine) - Nik Syazana Isyan Saffery (Protein in profiling of synovial membrane from osteoarthritis patients) , (Internal Examiner)
Contribution to external organisation
  1. (2020) Impact Planning Development Workshop - IIRG CYCLE 2/2019 (15th of July 2020), Research Cluster, University of Malaya
  2. (2020) Impact Planning Development Workshop - IIRG CYCLE 3/2020 (3rd of September 2020), Research Cluster, University of Malaya
  3. (2018) Research Collaboration with Professor Ammu Radakrishna from Monash University Malaysia for the project "Unravelling The Molecular Mechanisms Of Diffrentially Expressed Proteins Following Supplementation Of Tocotrienols In A Syngeneic Mouse Breast Cancer Model Using Quantitative Proetomics Profiling Strategies", Jeffrey Cheah School of Medicine & Health Sciences, Monash University Malaysia, National
  4. (2018) Research Collaboration with Dr Nurul Husna binti Mohd Shukri for the project "Investigating The Dynamic Changes in Human Milk Protein Composition of Malaysian Mothers at Different Stages of Lactation", Faculty of Medicine and Health Sciences, Universiti Putra Malaysia (UPM), National
  5. (2016) Research Collaboration with Dr. Yogeswaran Lokanathan, Tissue Engineering Centre, Universiti Kebangsaan Malaysia Medical Centre (UKMMC), National
Contribution to event
  1. (2021) Learn to Teach Again? - Introduction to Microsoft Teams for Teaching, University, (Panelist/Moderator)

SUPERVISION


Postgraduate Student
PhD/ Doctoral
  1. (2023) Periodontology and Implantology, NORUL HUSNA BINTI MOHAMAD HASSAN
  2. (2023) PROTEOMICS APPROACH TO UNDERSTAND ANTIMICROBIAL MECHANISM OF α-MANGOSTIN AS DISINFECTANT FOR DENTAL IMPRESSIONS, NURDIENA BINTI MOHAMED NASIR
  3. (2023) CIRCADIAN RHYTHMS OF SALIVARY PROTEINS AND METABOLITES IN RELATION TO ORAL HEALTH MAINTENANCE AND DEVELOPMENT AMONG PREGNANT WOMEN, NURSING MOTHERS AND INFANTS, MOHD AIZAT BIN ABDUL RAHIM
  4. (2023) DYNAMIC CHANGES OF HUMAN MILK DURING EXTENDED LACTATION : THE MULTI-OMICS APPROACHES, BRENDA LEECYOUS
  5. (2023) BIOACTIVITIES OF PSIDIUM GUAJAVA, NIGELLA SATIVA, AZADIRACHTA INDICA AND AVERRHOA BILIMBI IN ORAL TISSUE REPAIR: EVALUATING THEIR INTRACELLULAR AND EXTRACELLULAR RESPONSES IN HEALING, NOR FLORA BINTI NOR AHMAD RAJKUMAR
  6. (2023) THREE-DIMENSIONAL CRANIOMETRICS IDENTIFICATION MODEL AND CEPHALIC INDEX CLASSIFICATION OF MALAYSIAN SUB-ADULTS: A MULTI-SLICE COMPUTED TOMOGRAPHY STUDY, Sharifah Nabilah Syed Mohd Hamdan
  7. (2023) Unravelling the molecular mechanisms of differentially expressed proteins and metabolites following supplementation of tocotrienols in a syngeneic mouse breast cancer model using quantitative proteomics and metabolomics strategies, JEYA SEELA A/P ANANDHA RAO
Master
  1. (2023) CIRCADIAN RHYTHMICITY IN MILK: ELUCIDATING ITS ROLES IN MAINTAINING ORAL HEALTH IN INFANTS, QISTINA MARSYA BINTI AZIZ ZAINAL
  2. (2023) Label-Free Quantitative Analysis of Endometrial Receptivity Proteins in Infertile Women with Noncavity - Distorting Fibroids, AN-NISAA JASMINE BINTI MOHD ROSLEE
  3. (2018) Expression Of Inflammatory And Healing Biomakers Following Use Of Amp As An Adjunct To Scaling And Rsd In The Treatment Of Chronic Periodontitis, Muhammad Hadi Bin Mohd Hanifah
  4. (2018) -, MUHAMMAD HADI BIN MOHD HANIFAH

TEACHING


Bachelor
  1. (2020) DIA1001 - Oral Biology

PATENT/IPR


  • Piper Betle L.Extract Having Anti-Quorum Sensing Activity
    PATENT

SOCIAL RESPONSIBILITY ACTIVITIES


  • Exhibition: Local Organizing Committee (Booth), University of Malaya Impact Oriented Interdisciplinary Program (Iirg); Event: Gift of Love Celebration 2019: Empower Parents, Enable Breastfeeding; Organizer: The Breastfeeding Advocates Network (Tban), (03 Aug 2019 - 04 Aug 2019)
  • Participated in Cleft Lip and Palate (Clap) Charity Run 2019 Organized by Faculty of Dentistry, University of Malaya, (28 Apr 2019 - 28 Apr 2019)