PERSONAL DETAIL


DR. KHANG TSUNG FEI

Institute of Mathematical Sciences
Faculty of Science
 
  +603-79674171
  tfkhang@um.edu.my
 Institute of Mathematical Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, W.Persekutuan Kuala Lumpur, Malaysia
 
ResearcherID Link
  http://www.researcherid.com/rid/B-7787-2010

ACADEMIC QUALIFICATION
(Qualification), (Institution).



PROFESSIONAL
(Organisation), (Role), (Year), (Level).


  • Society for Molecular Biology and Evolution, Member, 2008 to 2009, (International)
  • International Society for Computational Biology, Member, 2010 to 2016, (International)
  • International Biometric Society, Member, 2013 to 2013, (International)
  • Society of Systematic Biologists, Member, 2014 to 2015, (International)
  • Systematics Association , Member, 2014 to 2015, (International)

ADMINISTRATIVE DUTIES
(Role), (Level), (Start date),(End Date).


  • Coordinator, Master of Bioinformatics Programme, Faculty, 01/07/2011 to 31/08/2013 (Master of Bioinformatics Programme)
  • Coordinator for Faculty of Science Handbook 2011/2012 production (ISB section) , Faculty, 01/03/2011 to 29/07/2011

AREAS OF EXPERTISE
(Area).


  • Mathematical Sciences, Statistics (Data Science)
  • Biostatistics (Applied statistics in medicine; quantitative methods in systematics and evolutionary biology)
  • Bioinformatics (Biological data mining)


RECENT SELECTED PUBLICATIONS
(Publication).


Article in Academic Journals

2018
  • Lee, S.C., Chua, L.L., Yap, S.H., Khang, T.F., Chan, Y.L., Azwa, I., Lewin, S.R., Kamarulzaman, A., Woo, Y.L., Lim, Y.A.L., Loke, P., Rajasuriar, R. (2018). Enrichment of gut-derived Fusobacterium is associated with suboptimal immune recovery in HIV-infected individuals. Scientific Reports, 8:14277. (ISI-Indexed)
  • Khang, T.F., Ng, C.M., Hamzah, N.A. (2018). Context-free dialogue classification using scorecards. Technical Report, UM-ISM-2018-01, Institute of Mathematical Sciences, University of Malaya. (Non-ISI/Non-SCOPUS)
  • Lim, I.L., Loo, A.V.P., Subrayan, V., Khang, T.F., See, M.H., Alip, A., Taib, N.A.M. (2018). Dosage-dependent reduction of macular pigment optical density in female breast cancer patients receiving tamoxifen adjuvant therapy. The Breast, 39, 117–122. (ISI-Indexed)
  • Cheah, P.L., Koh, C.C., Khang, T.F., Goh, K.L., Lau, P.C., Chin, K.F., Teoh, K.H., Toh, Y.F., Looi, L.M. (2018). Esophageal squamous cell carcinomas in a Malaysian cohort show a lack of association with human papillomavirus. Journal of Digestive Diseases, 19, 272-278. (ISI-Indexed)
  • Lee, B.K.B., Gan, C.P., Chang, J.K., Tan, J.L., Fadlullah, M.Z., Abdul Rahman, Z.A., Prime, S.S., Gutkind, J.S., Liew, C.S., Khang, T.F., Tan, A.C., Cheong, S.C. (2018). GENIPAC: A Genomic Information Portal for Head and Neck Cancer Cell Systems. Journal of Dental Research, 97(8), 909-916. (ISI-Indexed)

2017
  • Low, J.Z.B., Khang, T.F., Tammi, M.T. (2017). CORNAS: coverage-dependent RNA-Seq analysis of gene expression data without biological replicates. BMC Bioinformatics, 18(Suppl.16): 575 (ISI-Indexed)
  • Polgar, G., Ghanbarifardi, M., Milli, S., Agorreta, A., Aliabadian, M., Esmaeili, H.R., Khang, T.F. (2017). Ecomorphological adaptation in three mudskippers (Teleostei: Gobioidei: Gobiidae) from the Persian Gulf and the Gulf of Oman. Hydrobiologia, 795: 91-111. (ISI-Indexed)
  • Khang, T.F., Tan, S.H., Panha, S. & Mohamed, Z. (2017) . Molecular phylogenetics and sequence analysis of two cave-dwelling Dugesia species from Southeast Asia (Platyhelminthes: Tricladida: Dugesiidae). Raffles Bulletin of Zoology, 65: 515-524. (ISI-Indexed)
  • Lee, B.K.B., Tiong, K.H., Chang, J.K., Liew, C.S., Abdul Rahman, Z.A., Tan, A.C., Khang, T.F., Cheong, S.C. (2017). DeSigN: connecting gene expression with therapeutics for drug repurposing and development. BMC Genomics, 18(Suppl 1):934. (ISI-Indexed)

2016
  • Khang, T.F. (2016). A gamma approximation to the Bayesian posterior distribution of a discrete parameter of the Generalized Poisson model. arXiv preprint arXiv:1606.01749. (Non-ISI/Non-SCOPUS)
  • Wen, W.X., Soo, J.S.-S., Kwan, P.Y., Hong, E., Khang, T.F., Mariapun, S., Lee, C.S.-M., Hasan, S.N., Rajadurai, P., Yip, C.H., Mohd Taib, N.A. & Teo, S.H. (2016). Germline APOBEC3B deletion is associated with breast cancer risk in an Asian multi-ethnic cohort and with immune cell presentation. Breast Cancer Research, 18:56. (ISI-Indexed)
  • Khang, T.F., Soo, O.Y.M, Tan, W.B., Lim, L.H.S. (2016). Monogenean anchor morphometry: systematic value, phylogenetic signal, and evolution. PeerJ, 4:e1668. (ISI-Indexed)

2015
  • Khang, T.F., Lau, C.Y. (2015). Getting the most out of RNA-seq data analysis. PeerJ, 3: e1360. (ISI-Indexed)
  • Polgar, G., Khang, T.F., Chua, T. & Marshall, D.J. (2015). Gross mismatch between thermal tolerances and environmental temperatures in a tropical freshwater snail: climate warming and evolutionary implications. Journal of Thermal Biology,47:99-108. (ISI-Indexed)

2014
  • Khaw, K.W., Lam, H.H., Khang, T.F., Kadir, A.J.W.A. & Subrayan, V. (2014). Spectral-domain optical coherence tomography evaluation of postoperative cystoid macular oedema following phacoemulsification with intraoperative complication. BMC Ophthalmology, 14:16 (ISI-Indexed)

2013
  • Tan, J.L., Khang, T.F., Ngeow, Y.F. & Choo, S.W. (2013). A phylogenomic approach to bacterial subspecies classification: proof of concept in Mycobacterium abscessus. BMC Genomics, 14:879 (ISI-Indexed)
  • Ooi, Y.L., Khang, T.F., Naidu, M. & Fong, K.C.S. (2013). The structural effect of intravitreal Brilliant blue G and Indocyanine green in rats eyes. Eye, 27, 425-431. (ISI-Indexed)
  • Chook, J.B., Ngeow, Y.F., Khang, T.F., Ng, K.P., Tiang, Y.P. & Mohamed R. (2013). Comparative analysis of viral genomes from acute and chronic hepatitis B reveals novel variants associated with a lower rate of chronicity. Journal of Medical Virology, 85: 419-424. (ISI-Indexed)

2012
  • Lim, C.P., Loo, A.V.P., Khaw, K.W., Sthaneshwar, P., Khang, T.F., Hassan, M. & Subrayan, V. (2012) Plasma, aqueous and vitreous homocysteine levels in proliferative diabetic retinopathy. British Journal of Ophthalmology, 96, 704- 707. (ISI-Indexed)
  • Singh, S., Khang, T.F., Andiappan, H., Nissapatorn, V. & Subrayan, V. (2012) An age-adjusted seroprevalence study of Toxoplasma antibody in a Malaysian Ophthalmology Unit. Transactions of the Royal Society of Tropical Medicine and Hygiene, 106, 322-326. (ISI-Indexed)
  • Lam, H.H., Khaw, G.K.W., Khang, T.F. & Subrayan, V. (2012) Evaluation of macular thickness by SD-OCT. Ophthalmology, 119(1), 197-198. (ISI-Indexed)

2011
  • Jasvinder,S., Khang,T.F., Sarinder,K.K.S., Loo,V.P. & Subrayan,V. (2011) Agreement analysis of LENSTAR with other techniques of biometry. Eye, 25, 717-724. (ISI-Indexed)

2010
  • Khang, T.F. & Yap, V.B. (2010) Statistical analysis of binary data generated from multilocus dominant DNA data. Molecular Ecology Resources, 10, 995-1008. (ISI-Indexed)
  • Tan, W.B., Khang T.F. & Lim, L.H.S. (2010) Morphometric Analysis of Trianchoratus Price & Berry, 1966 (Monogenea: Heteronchocleidinae) from Channa spp. (Osteichthyes: Channidae) of Peninsular Malaysia. Raffles Bulletin of Zoology, 58 (1), 165-172. (ISI-Indexed)
  • Khang, T.F. & Yap, V.B. (2010) The apportionment of total genetic variation by categorical analysis of variance. Statistical Applications in Genetics & Molecular Biology, 9(1), Article 7 [online journal]. (ISI-Indexed)

2007
  • Khang, T.F. & Ong, S.H. (2007) A new generalization of the logarithmic distribution arising from the inverse trinomial distribution. Communications in Statistics - Theory & Methods, 36(1), 3-21. (ISI-Indexed)

AREAS OF RESEARCH
(Project title), (Role), (From)-(Until), (Level), (Source).


  • Computational Biochemical Analysis Of Chalcone Synthase Genes In Boesenbergia Rotunda, Consultant, 2015 - 2018, Geran Penyelidikan Universiti Malaya (UMRG Programme) - AFR (Frontier Science), (University)
  • miR-200 target(s) at tumour invasive front as biomarker(s), Consultant, 2013 - 2014, Geran Penyelidikan Universiti Malaya (UMRG) - HTM (Wellness), (University)
  • Trophic Connections Between Inshore Fisheries And Jeram Polychaete Reef (sustainable Fisheries), Consultant, 2013 - 2015, Geran Penyelidikan Universiti Malaya (UMRG Programme) - SUS (Sustainability Science), (University)
  • Taxonomic Annotation Of Multivariate Geometric Morphometric Data From Ligophorus Spp. (monogenea: Ancyrocephalidae) Using Data Mining Techniques, Principal Investigator(PI), 2012 - 2015, Geran Penyelidikan Universiti Malaya (UMRG) - SUS (Sustainability Science), (University)
  • Phylogenetic circumscription and morphological study of genus Desmotheca and Groutiella in Asia, Consultant, 2012 - 2015, Geran Penyelidikan Universiti Malaya (UMRG) - SUS (Sustainability Science), (University)
  • Population Genetic Studies of Dugesia batuensis BALL, 1970 (Turbellaria, Tricladida, Paludicola) from the Batu Caves, Selangor., Principal Investigator(PI), 2011 - 2012, Geran Penyelidikan Universiti Malaya (UMRG), (National)
  • Technique for Distinguishing Monogenean Species using Morphometric Data, Co-Investigator, 2010 - 2012, Fundamental Research Grant Scheme (FRGS), (National)

AWARDS AND RECOGNITIONS
(Name of Award), (Awarding Institution), (Year Awarded), (Level).


  • Board of Study Member, B.Sc. Data Science, M.Sc. Bioinformatics, Perdana University, Perdana University, 2017, (University)
  • Certificate of Excellent Service, University Malaya, 2015, (University)
  • Sijil Perkhidmatan Cemerlang, University of Malaya, 2015, (University)
  • Best Poster Award (Silver): Synteny Block Inference Using Orthocluster - How Orthologs Are Identified Matters! (Coauthored With Chow Kingsley), Incob, 2012, (International)
  • Nus Outstanding Teaching Assistant, National University of Singapore, 2006, (University)
  • Nus Outstanding Teaching Assistant, National University of Singapore, 2005, (University)
  • University Book Prize, University of Malaya, 2002, (University)

PRESENTATIONS
(Title), (Event), (Date Presented), (Organiser), (Level).


PRESENTER
  • Using R to Perform Statistical and Phylogenetic Analysis, Visiting lecturer, 2011-08-22 to 2011-08-22, Department of Biochemistry, Chulalongkorn University, Bangkok, Thailand., (University)
INVITED SPEAKER
  • Statistical Concepts and Issues in Bioinformatics Settings, International Workshop on Mathematical Modelling for Applications 2014 - Track A: Bioinformatics Models and Methods for Genomic Medicine and Drug Design, 2014-11-11 to 2014-11-13, Academy of Sciences Malaysia & MIMOS, Malaysia, (International)
  • Bioinformatics as an Essential Attitude for Next-Generation Scientists in Life Science and Medicine, 1st UMCDA Data Science Symposium, 2016-10-25 to 2016-10-25, UM Centre for Data Analytics, University of Malaya, (University)
  • Introduction to R, Bioinformatics Colloquium: Bioinformatics, Big Data, and Personalized Medicine, 2018-04-03 to 2018-04-04, Universitas Yarsi, Indonesia, (International)
  • Attacking the German Credit Problem using Machine Learning Methods, 2nd UMCDA Data Science Symposium, 2018-10-24 to 2018-10-24, UM Centre for Data Analytics, University of Malaya, (University)
  • Introductory Bioinformatics Workshop, APBioNet Outreach Programme, 2018-12-24 to 2018-12-28, Asia Pacific Bioinformatics Network (APBioNet) - Yangon University, Myanmar, (International)
  • Classification of Context-Free Conversations using the Scorecard Method, Topics in Data Science 2019, 2019-04-05 to 2019-04-05, INSPEM, Universiti Putra Malaysia, (National)
  • Applied Machine Learning in Psychology: A Case Study, Data Analytics and Revolutionizing Technology Forum, 2019-05-16 to 2019-05-16, HELP University, Malaysia, (University)
POSTER
  • Estimating average heterozygosity using multilocus dominant marker data: a maximum likelihood approach via the EM algorithm, 9th European Conference on Computational Biology, 2010-09-26 to 2010-09-29, ECCB10 Working Committee, (International)
  • Is bootstrap support really an indicator of robustness in phylogenetic trees? (with WH So), 11th International Conference on Bioinformatics, 2012-10-03 to 2012-10-05, Biotec, APBionet, King Mongkut's University of Technology Thonburi, (International)
  • Taxonomic annotation in Monogenea via multivariate statistical techniques (with JL Kuan, CY See, WC Chin, KKS Sarinder, WB Tan & LHS Lim), 11th International Conference on Bioinformatics, 2012-10-03 to 2012-10-05, Biotec, APBionet, King Mongkut's University of Technology Thonburi, (International)
  • Peculiar feed-forward loop network motifs in Escherichia coli (with EP Kok), 11th International Conference on Bioinformatics, 2012-10-03 to 2012-10-05, Biotec, APBionet, King Mongkut's University of Technology Thonburi, (International)
  • Synteny block inference using OrthoCluster - how orthologs are identified matters! (with K Chow), 11th International Conference on Bioinformatics, 2012-10-03 to 2012-10-05, Biotec, APBionet, King Mongkut's University of Technology Thonburi, (International)
  • Getting the most out of RNA-Seq data analysis, The 14th International Conference on Bioinformatics, 2015-09-09 to 2015-09-11, APBioNet, (International)

EXPERT LINKAGES
(Linkages Description), (Organisation), (Year of Involvement), (Duration), (Level).


  • Visiting lecturer, Department of Biochemistry, Chulalongkorn University, 2011, 1, (University)

CONTRIBUTION TO SOCIETY
(Contribution To Society), (Level), (Start Date), (End Date).


  • Coach - Team StatUM for CIMB Data Science Challenge 2016, (Local), 06/08/2016 until 07/08/2016

INTELLECTUAL PROPERTY RIGHTS
(Product Name), (Type), (Reference), (Year), (Level).


  • monogeneaGM R package, COPYRIGHT, 16/07/2015, (INTERNATIONAL)

SUPERVISION


POST GRADUATE STUDENT
(Name of Degree), (Name of Candidates), (Title of Thesis), (Academic Session)

Completed
  • Master Degree, Ngew Kok Yew, Application of Data Mining in Public Health: The 2005 -2015 United States Mortality Data Set, 2016/2017
  • Master Degree, Leong Foo Hoong, A Data Science Approach in Understanding Factors Associated with Risk of Human Language Extinction, 2016/2017
  • Master Degree, Lau Xiao Hoong, Analysis of the Human Tissue Expression Data and Drug-Target Network, 2015/2016
  • Master Degree, Lau Ching Yee, Identification Of Human Neurodegenerative Disease-Associated Pathways And Network Using Transcriptome Analysis, 2013/2014
  • Master Degree, Eeo Jun Jie, Community Structure Of The Jeram Polychaete Reef And Trophic Connections To Inshore Fishes And Shorebirds (with A.Sasekumar, V.C.Chong, A.Y.H. Then), 2012/2013
  • Master Degree, Cheong Leng San, Reanalysis of Public Microarray Data using Gene Set Enrichment Analysis: A Case Study using Pancreatic Cancer Data, 2011/2012
  • Master Degree, Elham Kalafi, The efficacy of alignment-based and alignment-free methods in reconstructing phylogenetic trees using complete mitochondrial DNA sequence, 2010/2011
  • Master Degree, Chow Kingsley, A comparative study of two orthologous gene identification methods on synteny block inference, 2010/2011
  • Master Degree, Kok Eng Piew, Peculiar feed forward loop network motifs in Escherichia coli, 2010/2011
  • Master Degree, So Wei Huo, An empirical assessment of the bootstrap support as an indicator of robustness in phylogenetic trees, 2010/2011
  • Master Degree, Sri Devi Ramarao, Bioinformatic analysis of degradome data from African oil palm (Elaies guineensis Jacq.) inflorescence (with Jennifer Ann Harikrishna), 2010/2011
  • Doctoral Degree (phd), Michelle Soo Oi Yoon, Systematic Biology of Four-Anchored Monogeneans (Family: Ancyrocephalidae) with Special Emphasis on the Genus Ligophorus Euzet & Suriano, 1977 in Peninsular Malaysia (with L.H.S Lim and A. Sasekumar), 2008/2009

Ongoing
  • Master Degree, Goh Jia Yin, Breast Cancer Predictive Analytics using Digital Mammograms, 2016/2017
  • Doctoral Degree (phd), Bernard Lee Kok Bang, Oral Cancer Genomics Data Mining and Integration for Predictive Therapeutics (with S.C.Cheong & Z.A.Abdul Rahman), 2015/2016
  • Doctoral Degree (phd), Phan Chin Lee, Genomic Characterization of Adult Philadelphia Positive Acute Lymphoblastic Leukemia (with C.C.Ng), 2014/2015
  • Doctoral Degree (phd), Joel Low Zi-bin, Computational Tools & Methods for Analysis of Elaeis guineensis (Oil Palm) Biology (with Jennifer Ann Harikrishna & Martti Tammi), 2013/2014
FIRST DEGREE/DIPLOMA/PRE-DEGREE
(Course Title), (Academic Session), (No. of Candidates)

Completed
  • Specific PCR Amplification of the Leptin (LEP) Gene for Detection of Porcine Contamination in Food Products, 2016/2017, 1
  • RNA-Seq analysis of the transcriptome of activated and resting human primary CD4+ T cells, 2013/2014, 1
  • Bioinformatic analysis of the ARMS2-HTRA1 region in age-related macular degeneration, 2013/2014, 1
  • Meta-analysis of microarray gene expression data on pancreatic cancer, 2013/2014, 1
  • Microarray data analysis of nasopharyngeal cancer, 2013/2014, 1
  • Euclidean Distance Matrix Analaysis of Ligophorus spp. (Monogenea: Ancyrocephalidae) using Geometric Morphometric Data, 2012/2013, 1
  • Gene Set Enrichment Analysis of Pediatric Acute Lymphoblastic Leukemia, 2012/2013, 1
  • Bioinformatic Discovery of Candidate Single Nucleotide Polymorphisms in the Genome of Hepatitis B Virus for Predicting Acuity and Chronicity of Infection, 2012/2013, 1
  • MOPHYTA: A bioinformatics resource for integrating taxonomic and phylogenetic information in Monogenea, 2011/2012, 1
  • Principal component analysis of Bravohollisia spp. (Monogenea: Ancyrocephalidae) from Pomadasys hasta using classical and landmark-based geometric morphometric data, 2011/2012, 1
  • Automated identification of Bravohollisia spp. (Monogenea: Ancyrocephalidae) using linear discriminant analysis, 2011/2012, 1
  • A preliminary assessment of the distribution of several ocular variables in the Malaysian population, 2010/2011, 1
  • Agreement analysis of several ocular biometry techniques, 2010/2011, 1

TEACHING
(Course Title), (Academic Session), (No of Student), (No of Contact Hours).


POST GRADUATE
  • Statistical Consultancy and Data Analysis, 2018/2019(2), 9, 0
  • Statistical Consultancy and Data Analysis, 2017/2018(2), 11, 0
  • Data Mining, 2017/2018(2), 12, 0
  • Data Mining, 2016/2017(2), 13, 0
  • Statistical Methods in Bioinformatics, 2015/2016(2), 5, 36
  • Applications of Algorithms in Bioinformatics, 2013/2014(2), 8, 42
  • Mathematics and Statistics in Bioinformatics, 2013/2014(1), 8, 42
  • Systems Biology, 2012/2013(1), 3, 30
  • Functional Bioinformatics, 2012/2013(1), 3, 30
  • Applications of Algorithms in Bioinformatics, 2012/2013(1), 3, 42
  • Systems Biology, 2011/2012(1), 14, 33
  • Mathematics and Statistics in Bioinformatics, 2011/2012(2), 4, 42
  • Applications of Algorithms in Bioinformatics, 2010/2011(3), 14, 56
  • Biostatistical Analysis and Interpretation, 2010/2011(2), 55, 21
  • Mathematics and Statistics in Bioinformatics, 2010/2011(2), 15, 56
  • Applications of Algorithms in Bioinformatics, 2009/2010(3), 7, 56
  • Mathematics and Statistics in Bioinformatics, 2009/2010(2), 8, 56
FIRST DEGREE
  • Mathematical Science Project, 2018/2019(2), 12, 0
  • Introduction to Probability Theory, 2018/2019(2), 4, 0
  • Introduction to Probability Theory, 2018/2019(1), 8, 0
  • Stochastic Processes, 2018/2019(1), 22, 0
  • Mathematical Science Project, 2018/2019(1), 14, 0
  • Introduction to Probability Theory, 2017/2018(2), 16, 0
  • Probability and Statistics II, 2016/2017(1), 18, 27
  • Further Mathematical Statistics, 2016/2017(1), 20, 36
  • Introduction to Multivariate Analysis, 2016/2017(1), 9, 48
  • Stochastic Processes, 2015/2016(1), 8, 34
  • Statistics, 2015/2016(1), 65, 40
  • Further Mathematical Statistics, 2015/2016(2), 20, 36
  • Stochastic Processes, 2014/2015(2), 6, 52
  • Further Mathematical Statistics, 2014/2015(2), 8, 52
  • Statistics, 2014/2015(1), 173, 100
  • Bioinformatics and Phylogenetics, 2013/2014(2), 24, 49
  • Probability and Statistics II, 2013/2014(1), 110, 28
  • Biostatistics, 2012/2013(2), 29, 42
  • Bioinformatics and Phylogenetics, 2012/2013(2), 21, 17
  • Adaptive Systems, 2012/2013(2), 26, 15
  • Mathematics in Biology, 2012/2013(2), 36, 42
  • Mathematics in Biology, 2011/2012(2), 26, 42
  • Adaptive Systems, 2011/2012(2), 22, 21
  • Biostatistics, 2011/2012(2), 49, 42
  • Mathematics in Biology, 2010/2011(2), 26, 42
  • Adaptive Systems, 2010/2011(2), 19, 17
  • Mathematics in Biology, 2009/2010(2), 22, 42
  • Adaptive Systems, 2009/2010(2), 19, 17