Institute of Mathematical Sciences
Faculty of Science
 Institute of Mathematical Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, W.Persekutuan Kuala Lumpur, Malaysia
ResearcherID Link

(Qualification), (Institution).

(Organisation), (Role), (Year), (Level).

  • Society for Molecular Biology and Evolution, Member, 2008 to 2009, (International)
  • International Society for Computational Biology, Member, 2010 to 2016, (International)
  • International Biometric Society, Member, 2013 to 2013, (International)
  • Society of Systematic Biologists, Member, 2014 to 2015, (International)
  • Systematics Association , Member, 2014 to 2015, (International)

(Role), (Level), (Start date),(End Date).

  • Coordinator, Master of Bioinformatics Programme, Faculty, 01/07/2011 to 31/08/2013 (Master of Bioinformatics Programme)
  • Coordinator for Faculty of Science Handbook 2011/2012 production (ISB section) , Faculty, 01/03/2011 to 29/07/2011


  • Mathematical Sciences, Statistics (Data Science)
  • Biostatistics (Applied statistics in medicine; quantitative methods in systematics and evolutionary biology)
  • Bioinformatics (Biological data mining)


Article in Academic Journals

  • Lee, S.C., Tang, M.S., Easton, A.V.A., Devlin, J.C., Chua, L.L., Cho, I., Moy, F.M., Khang, T.F., Lim, Y.A.L., Loke, P. (2019). Linking the effects of helminth infection, diet and the gut microbiota with human whole-blood signatures. PLoS Pathogens, 15(12): e1008066. (ISI-Indexed)

  • Lee, S.C., Chua, L.L., Yap, S.H., Khang, T.F., Chan, Y.L., Azwa, I., Lewin, S.R., Kamarulzaman, A., Woo, Y.L., Lim, Y.A.L., Loke, P., Rajasuriar, R. (2018). Enrichment of gut-derived Fusobacterium is associated with suboptimal immune recovery in HIV-infected individuals. Scientific Reports, 8:14277. (ISI-Indexed)
  • Khang, T.F., Ng, C.M., Hamzah, N.A. (2018). Context-free dialogue classification using scorecards. Technical Report, UM-ISM-2018-01, Institute of Mathematical Sciences, University of Malaya. (Non-ISI/Non-SCOPUS)
  • Lim, I.L., Loo, A.V.P., Subrayan, V., Khang, T.F., See, M.H., Alip, A., Taib, N.A.M. (2018). Dosage-dependent reduction of macular pigment optical density in female breast cancer patients receiving tamoxifen adjuvant therapy. The Breast, 39, 117–122. (ISI-Indexed)
  • Cheah, P.L., Koh, C.C., Khang, T.F., Goh, K.L., Lau, P.C., Chin, K.F., Teoh, K.H., Toh, Y.F., Looi, L.M. (2018). Esophageal squamous cell carcinomas in a Malaysian cohort show a lack of association with human papillomavirus. Journal of Digestive Diseases, 19, 272-278. (ISI-Indexed)
  • Lee, B.K.B., Gan, C.P., Chang, J.K., Tan, J.L., Fadlullah, M.Z., Abdul Rahman, Z.A., Prime, S.S., Gutkind, J.S., Liew, C.S., Khang, T.F., Tan, A.C., Cheong, S.C. (2018). GENIPAC: A Genomic Information Portal for Head and Neck Cancer Cell Systems. Journal of Dental Research, 97(8), 909-916. (ISI-Indexed)

  • Low, J.Z.B., Khang, T.F., Tammi, M.T. (2017). CORNAS: coverage-dependent RNA-Seq analysis of gene expression data without biological replicates. BMC Bioinformatics, 18(Suppl.16): 575 (ISI-Indexed)
  • Polgar, G., Ghanbarifardi, M., Milli, S., Agorreta, A., Aliabadian, M., Esmaeili, H.R., Khang, T.F. (2017). Ecomorphological adaptation in three mudskippers (Teleostei: Gobioidei: Gobiidae) from the Persian Gulf and the Gulf of Oman. Hydrobiologia, 795: 91-111. (ISI-Indexed)
  • Khang, T.F., Tan, S.H., Panha, S. & Mohamed, Z. (2017) . Molecular phylogenetics and sequence analysis of two cave-dwelling Dugesia species from Southeast Asia (Platyhelminthes: Tricladida: Dugesiidae). Raffles Bulletin of Zoology, 65: 515-524. (ISI-Indexed)
  • Lee, B.K.B., Tiong, K.H., Chang, J.K., Liew, C.S., Abdul Rahman, Z.A., Tan, A.C., Khang, T.F., Cheong, S.C. (2017). DeSigN: connecting gene expression with therapeutics for drug repurposing and development. BMC Genomics, 18(Suppl 1):934. (ISI-Indexed)

  • Khang, T.F. (2016). A gamma approximation to the Bayesian posterior distribution of a discrete parameter of the Generalized Poisson model. arXiv preprint arXiv:1606.01749. (Non-ISI/Non-SCOPUS)
  • Wen, W.X., Soo, J.S.-S., Kwan, P.Y., Hong, E., Khang, T.F., Mariapun, S., Lee, C.S.-M., Hasan, S.N., Rajadurai, P., Yip, C.H., Mohd Taib, N.A. & Teo, S.H. (2016). Germline APOBEC3B deletion is associated with breast cancer risk in an Asian multi-ethnic cohort and with immune cell presentation. Breast Cancer Research, 18:56. (ISI-Indexed)
  • Khang, T.F., Soo, O.Y.M, Tan, W.B., Lim, L.H.S. (2016). Monogenean anchor morphometry: systematic value, phylogenetic signal, and evolution. PeerJ, 4:e1668. (ISI-Indexed)

  • Khang, T.F., Lau, C.Y. (2015). Getting the most out of RNA-seq data analysis. PeerJ, 3: e1360. (ISI-Indexed)
  • Polgar, G., Khang, T.F., Chua, T. & Marshall, D.J. (2015). Gross mismatch between thermal tolerances and environmental temperatures in a tropical freshwater snail: climate warming and evolutionary implications. Journal of Thermal Biology,47:99-108. (ISI-Indexed)

  • Khaw, K.W., Lam, H.H., Khang, T.F., Kadir, A.J.W.A. & Subrayan, V. (2014). Spectral-domain optical coherence tomography evaluation of postoperative cystoid macular oedema following phacoemulsification with intraoperative complication. BMC Ophthalmology, 14:16 (ISI-Indexed)

  • Tan, J.L., Khang, T.F., Ngeow, Y.F. & Choo, S.W. (2013). A phylogenomic approach to bacterial subspecies classification: proof of concept in Mycobacterium abscessus. BMC Genomics, 14:879 (ISI-Indexed)
  • Ooi, Y.L., Khang, T.F., Naidu, M. & Fong, K.C.S. (2013). The structural effect of intravitreal Brilliant blue G and Indocyanine green in rats eyes. Eye, 27, 425-431. (ISI-Indexed)
  • Chook, J.B., Ngeow, Y.F., Khang, T.F., Ng, K.P., Tiang, Y.P. & Mohamed R. (2013). Comparative analysis of viral genomes from acute and chronic hepatitis B reveals novel variants associated with a lower rate of chronicity. Journal of Medical Virology, 85: 419-424. (ISI-Indexed)

  • Lim, C.P., Loo, A.V.P., Khaw, K.W., Sthaneshwar, P., Khang, T.F., Hassan, M. & Subrayan, V. (2012) Plasma, aqueous and vitreous homocysteine levels in proliferative diabetic retinopathy. British Journal of Ophthalmology, 96, 704- 707. (ISI-Indexed)
  • Singh, S., Khang, T.F., Andiappan, H., Nissapatorn, V. & Subrayan, V. (2012) An age-adjusted seroprevalence study of Toxoplasma antibody in a Malaysian Ophthalmology Unit. Transactions of the Royal Society of Tropical Medicine and Hygiene, 106, 322-326. (ISI-Indexed)
  • Lam, H.H., Khaw, G.K.W., Khang, T.F. & Subrayan, V. (2012) Evaluation of macular thickness by SD-OCT. Ophthalmology, 119(1), 197-198. (ISI-Indexed)

  • Jasvinder,S., Khang,T.F., Sarinder,K.K.S., Loo,V.P. & Subrayan,V. (2011) Agreement analysis of LENSTAR with other techniques of biometry. Eye, 25, 717-724. (ISI-Indexed)

  • Khang, T.F. & Yap, V.B. (2010) Statistical analysis of binary data generated from multilocus dominant DNA data. Molecular Ecology Resources, 10, 995-1008. (ISI-Indexed)
  • Tan, W.B., Khang T.F. & Lim, L.H.S. (2010) Morphometric Analysis of Trianchoratus Price & Berry, 1966 (Monogenea: Heteronchocleidinae) from Channa spp. (Osteichthyes: Channidae) of Peninsular Malaysia. Raffles Bulletin of Zoology, 58 (1), 165-172. (ISI-Indexed)
  • Khang, T.F. & Yap, V.B. (2010) The apportionment of total genetic variation by categorical analysis of variance. Statistical Applications in Genetics & Molecular Biology, 9(1), Article 7 [online journal]. (ISI-Indexed)

  • Khang, T.F. & Ong, S.H. (2007) A new generalization of the logarithmic distribution arising from the inverse trinomial distribution. Communications in Statistics - Theory & Methods, 36(1), 3-21. (ISI-Indexed)

(Project title), (Role), (From)-(Until), (Level), (Source).

  • Computational Biochemical Analysis Of Chalcone Synthase Genes In Boesenbergia Rotunda, Consultant, 2015 - 2018, Geran Penyelidikan Universiti Malaya (UMRG Programme) - AFR (Frontier Science), (University)
  • miR-200 target(s) at tumour invasive front as biomarker(s), Consultant, 2013 - 2014, Geran Penyelidikan Universiti Malaya (UMRG) - HTM (Wellness), (University)
  • Trophic Connections Between Inshore Fisheries And Jeram Polychaete Reef (sustainable Fisheries), Consultant, 2013 - 2015, Geran Penyelidikan Universiti Malaya (UMRG Programme) - SUS (Sustainability Science), (University)
  • Taxonomic Annotation Of Multivariate Geometric Morphometric Data From Ligophorus Spp. (monogenea: Ancyrocephalidae) Using Data Mining Techniques, Principal Investigator(PI), 2012 - 2015, Geran Penyelidikan Universiti Malaya (UMRG) - SUS (Sustainability Science), (University)
  • Phylogenetic circumscription and morphological study of genus Desmotheca and Groutiella in Asia, Consultant, 2012 - 2015, Geran Penyelidikan Universiti Malaya (UMRG) - SUS (Sustainability Science), (University)
  • Population Genetic Studies of Dugesia batuensis BALL, 1970 (Turbellaria, Tricladida, Paludicola) from the Batu Caves, Selangor., Principal Investigator(PI), 2011 - 2012, Geran Penyelidikan Universiti Malaya (UMRG), (National)
  • Technique for Distinguishing Monogenean Species using Morphometric Data, Co-Investigator, 2010 - 2012, Fundamental Research Grant Scheme (FRGS), (National)

(Name of Award), (Awarding Institution), (Year Awarded), (Level).

  • Board of Study Member, B.Sc. Data Science, M.Sc. Bioinformatics, Perdana University, Perdana University, 2017, (University)
  • Certificate of Excellent Service, University Malaya, 2015, (University)
  • Sijil Perkhidmatan Cemerlang, University of Malaya, 2015, (University)
  • Best Poster Award (Silver): Synteny Block Inference Using Orthocluster - How Orthologs Are Identified Matters! (Coauthored With Chow Kingsley), Incob, 2012, (International)
  • Nus Outstanding Teaching Assistant, National University of Singapore, 2006, (University)
  • Nus Outstanding Teaching Assistant, National University of Singapore, 2005, (University)
  • University Book Prize, University of Malaya, 2002, (University)

(Title), (Event), (Date Presented), (Organiser), (Level).

  • Statistical Concepts and Issues in Bioinformatics Settings, International Workshop on Mathematical Modelling for Applications 2014 - Track A: Bioinformatics Models and Methods for Genomic Medicine and Drug Design, 2014-11-11 to 2014-11-13, Academy of Sciences Malaysia & MIMOS, Malaysia, (International)
  • Bioinformatics as an Essential Attitude for Next-Generation Scientists in Life Science and Medicine, 1st UMCDA Data Science Symposium, 2016-10-25 to 2016-10-25, UM Centre for Data Analytics, University of Malaya, (University)
  • Introduction to R, Bioinformatics Colloquium: Bioinformatics, Big Data, and Personalized Medicine, 2018-04-03 to 2018-04-04, Universitas Yarsi, Indonesia, (International)
  • Attacking the German Credit Problem using Machine Learning Methods, 2nd UMCDA Data Science Symposium, 2018-10-24 to 2018-10-24, UM Centre for Data Analytics, University of Malaya, (University)
  • Introductory Bioinformatics Workshop, APBioNet Outreach Programme, 2018-12-24 to 2018-12-28, Asia Pacific Bioinformatics Network (APBioNet) - Yangon University, Myanmar, (International)
  • Classification of Context-Free Conversations using the Scorecard Method, Topics in Data Science 2019, 2019-04-05 to 2019-04-05, INSPEM, Universiti Putra Malaysia, (National)
  • Applied Machine Learning in Psychology: A Case Study, Data Analytics and Revolutionizing Technology Forum, 2019-05-16 to 2019-05-16, HELP University, Malaysia, (University)
  • Estimating average heterozygosity using multilocus dominant marker data: a maximum likelihood approach via the EM algorithm, 9th European Conference on Computational Biology, 2010-09-26 to 2010-09-29, ECCB10 Working Committee, (International)
  • Taxonomic annotation in Monogenea via multivariate statistical techniques (with JL Kuan, CY See, WC Chin, KKS Sarinder, WB Tan & LHS Lim), 11th International Conference on Bioinformatics, 2012-10-03 to 2012-10-05, Biotec, APBionet, King Mongkut's University of Technology Thonburi, (International)
  • Is bootstrap support really an indicator of robustness in phylogenetic trees? (with WH So), 11th International Conference on Bioinformatics, 2012-10-03 to 2012-10-05, Biotec, APBionet, King Mongkut's University of Technology Thonburi, (International)
  • Peculiar feed-forward loop network motifs in Escherichia coli (with EP Kok), 11th International Conference on Bioinformatics, 2012-10-03 to 2012-10-05, Biotec, APBionet, King Mongkut's University of Technology Thonburi, (International)
  • Synteny block inference using OrthoCluster - how orthologs are identified matters! (with K Chow), 11th International Conference on Bioinformatics, 2012-10-03 to 2012-10-05, Biotec, APBionet, King Mongkut's University of Technology Thonburi, (International)
  • Getting the most out of RNA-Seq data analysis, The 14th International Conference on Bioinformatics, 2015-09-09 to 2015-09-11, APBioNet, (International)
  • Using R to Perform Statistical and Phylogenetic Analysis, Visiting lecturer, 2011-08-22 to 2011-08-22, Department of Biochemistry, Chulalongkorn University, Bangkok, Thailand., (University)

(Linkages Description), (Organisation), (Year of Involvement), (Duration), (Level).

  • Visiting lecturer, Department of Biochemistry, Chulalongkorn University, 2011, 1, (University)

(Contribution To Society), (Level), (Start Date), (End Date).

  • Coach - Team StatUM for CIMB Data Science Challenge 2016, (Local), 06/08/2016 until 07/08/2016

(Product Name), (Type), (Reference), (Year), (Level).

  • monogeneaGM R package, COPYRIGHT, 16/07/2015, (INTERNATIONAL)


(Name of Degree), (Name of Candidates), (Title of Thesis), (Academic Session)

  • Master Degree, Chen Kah Wen, Predictive Analytics for an Auto Insurance Claim Problem, 2017/2018
  • Master Degree, Ngew Kok Yew, Application of Data Mining in Public Health: The 2005 -2015 United States Mortality Data Set, 2016/2017
  • Master Degree, Leong Foo Hoong, A Data Science Approach in Understanding Factors Associated with Risk of Human Language Extinction, 2016/2017
  • Master Degree, Lau Xiao Hoong, Analysis of the Human Tissue Expression Data and Drug-Target Network, 2015/2016
  • Master Degree, Lau Ching Yee, Identification Of Human Neurodegenerative Disease-Associated Pathways And Network Using Transcriptome Analysis, 2013/2014
  • Master Degree, Eeo Jun Jie, Community Structure Of The Jeram Polychaete Reef And Trophic Connections To Inshore Fishes And Shorebirds (with A.Sasekumar, V.C.Chong, A.Y.H. Then), 2012/2013
  • Master Degree, Cheong Leng San, Reanalysis of Public Microarray Data using Gene Set Enrichment Analysis: A Case Study using Pancreatic Cancer Data, 2011/2012
  • Master Degree, Elham Kalafi, The efficacy of alignment-based and alignment-free methods in reconstructing phylogenetic trees using complete mitochondrial DNA sequence, 2010/2011
  • Master Degree, Chow Kingsley, A comparative study of two orthologous gene identification methods on synteny block inference, 2010/2011
  • Master Degree, Kok Eng Piew, Peculiar feed forward loop network motifs in Escherichia coli, 2010/2011
  • Master Degree, So Wei Huo, An empirical assessment of the bootstrap support as an indicator of robustness in phylogenetic trees, 2010/2011
  • Master Degree, Sri Devi Ramarao, Bioinformatic analysis of degradome data from African oil palm (Elaies guineensis Jacq.) inflorescence (with Jennifer Ann Harikrishna), 2010/2011
  • Doctoral Degree (phd), Michelle Soo Oi Yoon, Systematic Biology of Four-Anchored Monogeneans (Family: Ancyrocephalidae) with Special Emphasis on the Genus Ligophorus Euzet & Suriano, 1977 in Peninsular Malaysia (with L.H.S Lim and A. Sasekumar), 2008/2009

  • Doctoral Degree (phd), Cui Zhuang, Statistical Modelling of Microbiome Data, 2019/2020
  • Master Degree, Goh Jia Yin, Breast Cancer Predictive Analytics using Digital Mammograms, 2016/2017
  • Doctoral Degree (phd), Bernard Lee Kok Bang, Oral Cancer Genomics Data Mining and Integration for Predictive Therapeutics (with S.C.Cheong & Z.A.Abdul Rahman), 2015/2016
  • Doctoral Degree (phd), Phan Chin Lee, Genomic Characterization of Adult Philadelphia Positive Acute Lymphoblastic Leukemia (with C.C.Ng), 2014/2015
  • Doctoral Degree (phd), Joel Low Zi-bin, Computational Tools & Methods for Analysis of Elaeis guineensis (Oil Palm) Biology (with Jennifer Ann Harikrishna & Martti Tammi), 2013/2014
(Course Title), (Academic Session), (No. of Candidates)

  • Specific PCR Amplification of the Leptin (LEP) Gene for Detection of Porcine Contamination in Food Products, 2016/2017, 1
  • RNA-Seq analysis of the transcriptome of activated and resting human primary CD4+ T cells, 2013/2014, 1
  • Bioinformatic analysis of the ARMS2-HTRA1 region in age-related macular degeneration, 2013/2014, 1
  • Meta-analysis of microarray gene expression data on pancreatic cancer, 2013/2014, 1
  • Microarray data analysis of nasopharyngeal cancer, 2013/2014, 1
  • Euclidean Distance Matrix Analaysis of Ligophorus spp. (Monogenea: Ancyrocephalidae) using Geometric Morphometric Data, 2012/2013, 1
  • Gene Set Enrichment Analysis of Pediatric Acute Lymphoblastic Leukemia, 2012/2013, 1
  • Bioinformatic Discovery of Candidate Single Nucleotide Polymorphisms in the Genome of Hepatitis B Virus for Predicting Acuity and Chronicity of Infection, 2012/2013, 1
  • MOPHYTA: A bioinformatics resource for integrating taxonomic and phylogenetic information in Monogenea, 2011/2012, 1
  • Principal component analysis of Bravohollisia spp. (Monogenea: Ancyrocephalidae) from Pomadasys hasta using classical and landmark-based geometric morphometric data, 2011/2012, 1
  • Automated identification of Bravohollisia spp. (Monogenea: Ancyrocephalidae) using linear discriminant analysis, 2011/2012, 1
  • A preliminary assessment of the distribution of several ocular variables in the Malaysian population, 2010/2011, 1
  • Agreement analysis of several ocular biometry techniques, 2010/2011, 1

(Course Title), (Academic Session), (No of Student), (No of Contact Hours).

  • Statistical Consultancy and Data Analysis, 2018/2019(2), 9, 0
  • Statistical Consultancy and Data Analysis, 2017/2018(2), 11, 0
  • Data Mining, 2017/2018(2), 12, 0
  • Data Mining, 2016/2017(2), 13, 0
  • Statistical Methods in Bioinformatics, 2015/2016(2), 5, 36
  • Applications of Algorithms in Bioinformatics, 2013/2014(2), 8, 42
  • Mathematics and Statistics in Bioinformatics, 2013/2014(1), 8, 42
  • Systems Biology, 2012/2013(1), 3, 30
  • Functional Bioinformatics, 2012/2013(1), 3, 30
  • Applications of Algorithms in Bioinformatics, 2012/2013(1), 3, 42
  • Systems Biology, 2011/2012(1), 14, 33
  • Mathematics and Statistics in Bioinformatics, 2011/2012(2), 4, 42
  • Applications of Algorithms in Bioinformatics, 2010/2011(3), 14, 56
  • Biostatistical Analysis and Interpretation, 2010/2011(2), 55, 21
  • Mathematics and Statistics in Bioinformatics, 2010/2011(2), 15, 56
  • Applications of Algorithms in Bioinformatics, 2009/2010(3), 7, 56
  • Mathematics and Statistics in Bioinformatics, 2009/2010(2), 8, 56
  • Mathematical Science Project, 2019/2020(1), 17, 0
  • Statistics, 2019/2020(1), 296, 0
  • Introduction to Probability Theory, 2019/2020(1), 24, 0
  • Mathematical Science Project, 2018/2019(2), 12, 0
  • Introduction to Probability Theory, 2018/2019(2), 4, 0
  • Introduction to Probability Theory, 2018/2019(1), 8, 0
  • Stochastic Processes, 2018/2019(1), 22, 0
  • Mathematical Science Project, 2018/2019(1), 14, 0
  • Introduction to Probability Theory, 2017/2018(2), 16, 0
  • Probability and Statistics II, 2016/2017(1), 18, 27
  • Further Mathematical Statistics, 2016/2017(1), 20, 36
  • Introduction to Multivariate Analysis, 2016/2017(1), 9, 48
  • Statistics, 2015/2016(1), 65, 40
  • Stochastic Processes, 2015/2016(1), 8, 34
  • Further Mathematical Statistics, 2015/2016(2), 20, 36
  • Stochastic Processes, 2014/2015(2), 6, 52
  • Statistics, 2014/2015(1), 173, 100
  • Further Mathematical Statistics, 2014/2015(2), 8, 52
  • Probability and Statistics II, 2013/2014(1), 110, 28
  • Bioinformatics and Phylogenetics, 2013/2014(2), 24, 49
  • Biostatistics, 2012/2013(2), 29, 42
  • Adaptive Systems, 2012/2013(2), 26, 15
  • Mathematics in Biology, 2012/2013(2), 36, 42
  • Bioinformatics and Phylogenetics, 2012/2013(2), 21, 17
  • Mathematics in Biology, 2011/2012(2), 26, 42
  • Adaptive Systems, 2011/2012(2), 22, 21
  • Biostatistics, 2011/2012(2), 49, 42
  • Mathematics in Biology, 2010/2011(2), 26, 42
  • Adaptive Systems, 2010/2011(2), 19, 17
  • Adaptive Systems, 2009/2010(2), 19, 17
  • Mathematics in Biology, 2009/2010(2), 22, 42