Curriculum Vitae

ASSOCIATE PROF. DR. TAN CHOO HOCK

Associate Professor
  • Department of Pharmacology
    Faculty of Medicine
  • 0379674703

BIOGRAPHY


Choo Hock Tan (MBBS, PhD, MD) is based at the Venom Research and Toxicology Laboratory (Vetox Lab) of the Department of Pharmacology, Faculty of Medicine, University of Malaya. His research interests span a wide range of subjects in the field of venom toxinology, which include molecular and functional characterization of venoms, medical pharmacology of antivenom (production, kinetics and dynamics), “-omics” of venomous species and toxins in drug discovery. Choo Hock enjoys passionately his research activities, from collecting specimens in the wild to conducting experiments in his laboratory. He is also the supervisor and mentor to undergraduate and postgraduate students working on the various aspects of toxinology, and his team is in close collaboration with local and international researchers, who share a common aim of translating new knowledge into scientific application and medical practice. At present, their findings have been presented in many conferences and published in numerous academic journals and books.

Choo Hock is also affiliated to several professional bodies, for instance, he serves as the Honorary Secretary for the Malaysian Society on Toxinology, and is a member of the WHO Snakebite Envenoming Roster of Experts. He is also a recipient of awards such as the Academic Training Fellowship from the Malaysian government and the International Award of Young Scientist from the Japanese Association of Laboratory Animal Sciences, Japan. Choo Hock’s other “non-venomous” research interests include problem-based learning, prescribing skills training and inter-professional learning in medical education.

AREAS OF EXPERTISE


  • MOLECULAR AND FUNCTIONAL TOXINOLOGY
    Venom-gland transcriptomics, venom proteomics, antivenomics
  • MEDICAL PHARMACOLOGY
    Antivenom, neutralization, antibody production, immonological profiling
  • PRESCRIBING SKILLS TRANING
    Prescribing competence, training
  • MEDICAL EDUCATION
    Problem-based learning
  • TOXINOLOGY
    Venom, toxin, characterisation, purification

ACADEMIC QUALIFICATION


  • MD, (Medicine)
    Universiti Malaya (UM)
  • PhD, (Pharmacology and Toxinology)
    Universiti Malaya (UM)
  • MBBS (MALAYA), (Medicine and Surgery)
    Universiti Malaya (UM)

ADMINISTRATIVE DUTIES


  • Committee Member, Internationalization Unit
    01 Jul 2023 - 31 Dec 2024 (Dean Office, Faculty of Medicine)
  • Coordinator
    01 Jan 2023 - 30 Apr 2024 (Dean Office, Faculty of Medicine)
  • Committee member, Departmental/MERDU Curriculum Committee (Postgraduate)
    18 Mar 2015 - present (Dean Office, Faculty of Medicine)
  • Officer in-charge, Health screening programme for staff/students using laboratory animals in research (Department of Pharmacology)
    16 Jul 2013 - present (Department of Pharmacology, Faculty of Medicine)
  • Member, Central Unit of Advanced Research Imaging
    13 Nov 2013 - present (Department of Pharmacology, Faculty of Medicine)
  • Secretary and organising committee, Internal Symposium on AMSEM 2014
    18 Dec 2013 - present (International)
  • Mentor, Persatuan Mahasiswa Pulau Pinang
    01 Jan 2015 - present (University Malaya)
  • Pharmacology Dept Asst. Coordinator for Stage 2, 3..1, 3.2 and Departmental Coordinator for UMMP PBL
    30 Dec 2014 - present (Department of Pharmacology, Faculty of Medicine)
  • Medical officer, Health screening programme for students and staff handling laboratory animals (Faculty of Medicine)
    18 Oct 2013 - present (Department of Pharmacology, Faculty of Medicine)
  • Committee Members
    03 Jan 2022 - 31 Dec 2023 (Department of Pharmacology, Faculty of Medicine)
  • Coordinator
    14 Jul 2022 - 30 Sep 2023 (Department)
  • Committee Members
    01 Jun 2020 - 31 Dec 2022 (Department of Pharmacology, Faculty of Medicine)
  • Coordinator
    01 Jan 2019 - 30 Jun 2022 (Department of Pharmacology, Faculty of Medicine)
  • Coordinator, Science Cafe Faculty of Medicine
    02 Jan 2018 - 31 Dec 2021 (Dean Office, Faculty of Medicine)
  • Coordinator
    09 Sep 2016 - 31 Dec 2020 (Dean Office, Faculty of Medicine)
  • Deputy Head
    01 Oct 2018 - 31 Dec 2020 (Dean Office, Faculty of Medicine)
  • Coordinator
    01 Jan 2019 - 31 Dec 2019 (Dean Office, Faculty of Medicine)
  • Coordinator
    01 Jan 2016 - 31 Dec 2018 (Department of Pharmacology, Faculty of Medicine)
  • Coordinator
    09 Sep 2016 - 31 Dec 2018 (Dean Office, Faculty of Medicine)
  • Coordinator
    01 Jan 2016 - 31 Dec 2018 (Department of Pharmacology, Faculty of Medicine)
  • Evaluator for Postgraduate Research Fund(PPP) application
    01 Oct 2015 - 30 Sep 2018 (Department of Pharmacology, Faculty of Medicine)
  • Acting Head of Department
    25 Jun 2018 - 10 Aug 2018 (Dean Office, Faculty of Medicine)
  • Committee
    18 Mar 2015 - 19 Mar 2018 (Dean Office, Faculty of Medicine)
  • Coordinator
    03 Jan 2017 - 31 Dec 2017 (University Malaya)
  • Comittee member
    28 Aug 2017 - 31 Dec 2017 (Department of Pharmacology, Faculty of Medicine)
  • Pengerusi, Jawakankuasa Penilaian Harga Perolehan Bekalan / Perkihdmatan
    19 Mar 2015 - 31 Dec 2015 (Department of Pharmacology, Faculty of Medicine)
  • Ahli, Jawakankuasa Penilaian Harga Perolehan Bekalan / Perkihdmatan
    14 Sep 2015 - 31 Dec 2015 (Department of Pharmacology, Faculty of Medicine)
  • Committee member (Scientific) for FOM Research Week 2015, 11-15 May 2015
    11 May 2015 - 31 Dec 2015 (University Malaya)
  • Committee member for Golden Helix Symposia 2015, 11-13 March 2015
    11 Mar 2015 - 31 Dec 2015 (International)
  • Committee member and Emcee for Snakebite Envenoming Management Workshop in Kuala Lumpur 2015
    27 Apr 2015 - 31 Dec 2015 (National)
  • Member, PBL Case Design Committee
    18 Mar 2013 - 17 Mar 2015 (Department of Pharmacology, Faculty of Medicine)
  • Academic advisor, Phase II MBBS session 2013/2014
    01 Jan 2014 - 31 Dec 2014 (Department of Pharmacology, Faculty of Medicine)
  • Organising committee for MST Short Seminar Series I/2014 at University of Malaya
    12 Feb 2014 - 31 Dec 2014 (National)
  • Pengerusi, Jawakankuasa Penilaian Harga Perolehan Bekalan / Perkihdmatan
    10 Feb 2014 - 31 Dec 2014 (Department of Pharmacology, Faculty of Medicine)

MEMBERSHIPS


  • LABORATORY ANIMAL SCIENCE ASSOCIATION OF MALAYSIA, LIFE MEMBER
    Since 2019 (International)
  • INTERNATIONAL SOCIETY ON TOXINOLOGY, LIFE MEMBER
    Since 2019 (International)
  • EDITOR FOR SPECIAL ISSUE (TOXINS, IF: 5.075, WOS JOURNAL), EDITORIAL BOARD
    2022 to 2023 (International)
  • CHIEF EDITOR, EDITORIAL BOARD
    2022 to 2023 (National)
  • MEMBER AND HONORARY SECRETARY, SECRETARY
    2021 to 2023 (National)
  • EDITOR, EDITORIAL BOARD
    2021 to 2023 (National)
  • FINANCIALLY ACTIVE MEMBER AND ELECTED HONORARY SECRETARY, SECRETARY
    2013 to 2022 (National)
  • YOUNG SCIENTIST NETWORK-ACADEMY SCIENCES OF MALAYSIA (YSN-ASM), AFFILIATE MEMBER
    2018 to 2021 (National)
  • MALAYSIAN SOCIETY ON TOXINOLOGY, ACADEMIC MEMBER
    2013 to 2021 (International)
  • MALAYSIAN SOCETY ON TOXINOLOGY, HONORARY SECRETARY
    2013 to 2021 (National)
  • MALAYSIAN MEDICAL COUNCIL, MEMBER
    2007 to 2021 (National)
  • MALAYSIAN SOCIETY ON TOXINOLOGY, HONORARY SECRETARY
    2017 to 2019 (National)
  • INTERNATIONAL SOCIETY ON TOXINOLOGY, MEMBER
    2018 to 2018 (International)
  • MALAYSIAN SOCIETY ON TOXINOLOGY, HONORARY SECRETARY
    2015 to 2017 (National)
  • LABORATORY ANIMAL SCIENCE ASSOCIATION OF MALAYSIA, ACADEMIC MEMBER
    2013 to 2015 (University)
  • MALAYSIAN SOCIETY ON TOXINOLOGY, HONORARY SECRETARY
    2013 to 2015 (National)

AWARD AND STEWARDSHIP


  • MSPP Young Investigator Award
    Malaysian Society of Pharmacology & Physiology, 2021 (National)
  • Silver, Oral Presentation - LITEC 2020 (The International Learning Improvement and Teaching Enhancement Conference 2020)
    ADeC, University of Malaya, 2020 (International)
  • Second Runner-up, FameLab Science Communication Contest
    British Council, 2020 (National)
  • Certificate of Recognition: Chair for invited speech session
    Asia-Pacific Association of Medical Toxicology, 2019 (International)
  • Certificate of Appreciation: Moderator and chair for invited speech session
    National Poison Center and Taipei Veterans General Hospital, 2019 (International)
  • Certificate of Recognition: Finalist pitching for MRUN Young Researcher Grant Scheme 2019
    Malaysian Research University Network (MRUN), 2019 (National)
  • EXCELLENCE SERVICE AWARD
    University of Malaya, 2019 (University)
  • Certificate of Recognition: National Finalist in Fame Lab Talking Science 2018, Malaysia.
    Malaysian Industry-Government for High Technology (MiGHT) AND Bristish Council (UK), 2018 (National)
  • Certificate of Appreciation: Problem-based learning (PBL) student training workshop for UMMP
    University of Malaya, 2016 (University)
  • Certificate of Appreciation: Neuromuscular Pharmacology Seminar & Nerve Muscle Preparation Workshop
    University of Malaya, 2016 (University)
  • Certificate of Appreciation in recognition of valuable contributions at 4th International ASEAN Marine Animals & Snake Envenoming (Poisoning) Management
    Malaysian Society on Toxinology and University of Science Malaysia, 2016 (International)
  • Certificate of Appreciation in recognition as invited speaker
    University Technology MARA Selangor, 2016 (National)
  • Certificate of Appreciation: Prescribing Skills Training Workshop - MBBS Phase IIIB (Junior), 2015/2017
    University of Malaya, 2016 (University)
  • Certificate of Appreciation: Problem-based learning (PBL) Tutor Training Workshop for UMMP
    University of Malaya, 2016 (University)
  • EXCELLENCE SERVICE AWARD
    University of Malaya, 2016 (University)
  • CERTIFICATE OF EXCELLENT SERVICE
    University of Malaya, 2015 (University)
  • Certificate of Appreciation for Significant Contribution as Hon. Secretary of the Malaysian Society on Toxinology 2013-2015
    Malaysian Society on Toxinology, 2015 (National)
  • Cover Art Award for Special Issue (FOM Research Week 2015) in JUMMEC
    University of Malaya, 2015 (National)
  • Sijil Perkhidmatan Cemerlang
    University of Malaya, 2015 (University)
  • UM EXCELLENCE AWARD
    NAIB CANSELOR, 2014 (University)
  • University of Malaya Excellence Award on "Completion of PhD within 3 years"
    Unviersity of Malaya, 2014 (University)
  • International Award (Young Scientist)
    Japanese Association of Laboratory Animal Sciences, 2014 (International)
  • Best Poster Presentation
    38th MSBMB Conference, 2013 (National)
  • Post-graduate Research Award (Ph.D level)
    Post-graduate Research Day & 17th MSMBB, Kuala Lumpur., 2012 (National)
  • 3-Minute Thesis (Ph.D): Faculty of Medicine, University of Malaya
    University of Malaya, 2012 (University)
  • Travel Grant Award
    Japanese Pharmacological Society, 2011 (International)
  • Best Oral Free Communication
    24th Scientific Meeting of the Malaysian Society of Pharmacology and Physiology, 2010 (National)
  • Student Award
    Asia-Pacific Joint PBL Conference, Taip, 2010 (International)
  • Skim Latihan Akademik Institut Pengajian Tinggi Awam (SLAI) - Scholarship Award
    University of Malaya and MOHE, 2010 (National)
  • Best Poster Presentation
    18th Scientific Meeting of the Malaysian Society for Molecular Biology and Biotechnology, 2009 (National)

PUBLICATIONS


Article in Journal
WoS
  1. Chan, Yi Wei; Tan, Kae Yi; Tan, Choo Hock (2022). Preclinical assessment of VPEAV, a new trivalent antivenom for elapid snakebite envenoming in the Philippines: Proteomics, immunoreactivity and toxicity neutralization, TOXICON. 220. doi:10.1016/j.toxicon.2022.106942
  2. Chong, Ho Phin; Tan, Kae Yi; Liu, Bing-Sin; Sung, Wang-Chou; Tan, Choo Hock (2022). Cytotoxicity of Venoms and Cytotoxins from Asiatic Cobras (Naja kaouthia, Naja sumatrana, Naja atra) and Neutralization by Antivenoms from Thailand, Vietnam, and Taiwan, TOXINS. 14(5). doi:10.3390/toxins14050334
  3. Choo, Siew Woh; Chong, Ju Lian; Gaubert, Philippe; Hughes, Alice Catherine; O'Brien, Stephen; Chaber, Anne-Lise; Antunes, Agostinho; Platto, Sara; Sun, Nick Ching-Min; Yu, Li; Koepfli, Klaus-Peter; Suwal, Tulshi Laxmi; Thakur, Mukesh; Ntie, Stephan; Panjang, Elisa; Kumaran, Jayaraj Vijaya; Mahmood, Tariq; Heighton, Sean P.; Dorji, Dago; Gonedele, Bi Sery; Nelson, Bryan Raveen; Djagoun, Chabi A. M. S.; Loh, Ing Hoe; Kaspal, Prativa; Pauklin, Siim; Michelena, Toby; Zhu, Hongxiang; Lipovich, Leonard; Tian, Xuechen; Deng, Siwei; Mason, Christopher E.; Hu, Jingyang; White, Robert; Jakubovics, Nicholas S.; Wee, Wei Yee; Tan, Tze King; Wong, Kum Thong; Paterson, Steve; Chen, Ming; Zhang, Yixin; Othman, Rofina Yasmin; Brown, Larry C.; Shen, Bairong; Shui, Guanghou; Ang, Mia Yang; Zhao, Yunqi; Li, Yongming; Zhang, Bo; Chong, Cheng Tung; Meng, Yu; Wong, Aloysius; Su, Jianzhong; Omar, Hasmahzaiti; Shen, Hua; Tan, Choo Hock; Xu, Hongyu; Paterson, Ian C.; Wang, Minyan; Chan, Chee-Kai; Zhang, Siyuan; Dutta, Avirup; Tee, Tay Sun; Juvigny-Khenafou, Noel P. D.; Mutha, Naresh V. R.; Aziz, Muhamad Afiq (2022). A collective statement in support of saving pangolins, SCIENCE OF THE TOTAL ENVIRONMENT. 824. doi:10.1016/j.scitotenv.2022.153666
  4. Stazi, Marco; Fabris, Federico; Tan, Kae Yi; Megighian, Aram; Rubini, Alessandro; Mattarei, Andrea; Negro, Samuele; D'Este, Giorgia; Lista, Florigio; Rossetto, Ornella; Tan, Choo Hock; Montecucco, Cesare (2022). An agonist of the CXCR4 receptor is therapeutic for the neuroparalysis induced by Bungarus snakes envenoming, CLINICAL AND TRANSLATIONAL MEDICINE. 12(1). doi:10.1002/ctm2.651
  5. Tan, Choo Hock (2022). Snake Venomics: Fundamentals, Recent Updates, and a Look to the Next Decade, TOXINS. 14(4). doi:10.3390/toxins14040247
  6. Tan, Choo Hock; Bourges, Aymeric; Tan, Kae Yi (2022). King Cobra and snakebite envenomation: on the natural history, human-snake relationship and medical importance of Ophiophagus hannah, JOURNAL OF VENOMOUS ANIMALS AND TOXINS INCLUDING TROPICAL DISEASES. 27. doi:10.1590/1678-9199-JVATITD-2021-0051
  7. Tan, Choo Hock; Lingam, Thava Malar Changra; Tan, Kae Yi (2022). Varespladib (LY315920) rescued mice from fatal neurotoxicity caused by venoms of five major Asiatic kraits (Bungarus spp.) in an experimental envenoming and rescue model, ACTA TROPICA. 227. doi:10.1016/j.actatropica.2021.106289
  8. Tan, Choo Hock; Oh, Angeline Mei Feng; Wong, Kin Ying; Liew, Jia Lee; Tan, Nget Hong; Tan, Kae Yi (2022). On characterizing the Red-headed Krait (Bungarus flaviceps) venom: Decomplexation proteomics, immunoreactivity and toxicity cross-neutralization by hetero-specific antivenoms, COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS. 43. doi:10.1016/j.cbd.2022.101006
  9. Tan, Choo Hock; Tan, Kae Yi; Jackson, Timothy N. W. (2022). Editorial: Venoms and Toxins: Functional Omics and Pharmacological Insights, FRONTIERS IN PHARMACOLOGY. 13. doi:10.3389/fphar.2022.887513
  10. Tan, Choo Hock; Tan, Kae Yi; Wong, Kin Ying; Tan, Nget Hong; Chong, Ho Phin (2022). Equatorial Spitting Cobra (Naja sumatrana) from Malaysia (Negeri Sembilan and Penang), Southern Thailand, and Sumatra: Comparative Venom Proteomics, Immunoreactivity and Cross-Neutralization by Antivenom, TOXINS. 14(8). doi:10.3390/toxins14080522
  11. Tan, Kae Yi; Shamsuddin, Nor Naimah; Tan, Choo Hock (2022). Sharp-nosed Pit Viper (Deinagkistrodon acutus) from Taiwan and China: A comparative study on venom toxicity and neutralization by two specific antivenoms across the Strait, ACTA TROPICA. 232. doi:10.1016/j.actatropica.2022.106495
  12. Faisal, T., Tan, K. Y., Tan, N. H., Sim, S. M., Gnanathasan, C. A., & Tan, C. H. (2021). Proteomics, toxicity and antivenom neutralization of Sri Lankan and Indian Russell's viper (Daboia russelii) venoms. Journal of Venomous Animals and Toxins Including Tropical Diseases, 27, 15. doi: 10.1590/1678-9199-jvatitd-2020-0177
  13. Lee, L. P., Tan, K. Y., & Tan, C. H. (2021). Snake venom proteomics and antivenomics of two Sundaic lance-headed pit vipers: Trimeresurus wiroti (Malaysia) and Trimeresurus puniceus (Indonesia). Comparative Biochemistry and Physiology D-Genomics & Proteomics, 40, 13. doi: 10.1016/j.cbd.2021.100875
  14. Lingam, T. M. C., Tan, K. Y., & Tan, C. H. (2021). Capillary leak syndrome induced by the venoms of Russell's Vipers (Daboia russelii and Daboia siamensis) from eight locales and neutralization of the differential toxicity by three snake antivenoms. Comparative Biochemistry and Physiology C-Toxicology & Pharmacology, 250, 6. doi: 10.1016/j.cbpc.2021.109186
  15. Oh, A. M. F., Tan, K. Y., Tan, N. H., & Tan, C. H. (2021). Proteomics and neutralization of Bungarus multicinctus (Many-banded Krait) venom: Intra-specific comparisons between specimens from China and Taiwan. Comparative Biochemistry and Physiology C-Toxicology & Pharmacology, 247, 10. doi: 10.1016/j.cbpc.2021.109063
  16. Palasuberniam, Praneetha; Chan, Yi Wei; Tan, Kae Yi; Tan, Choo Hock (2021). Snake Venom Proteomics of Samar Cobra (Naja samarensis) from the Southern Philippines: Short Alpha-Neurotoxins as the Dominant Lethal Component Weakly Cross-Neutralized by the Philippine Cobra Antivenom, FRONTIERS IN PHARMACOLOGY. 12. doi:10.3389/fphar.2021.727756
  17. Tan, C. H., & Tan, K. Y. (2021). De Novo Venom-Gland Transcriptomics of Spine-Bellied Sea Snake (Hydrophis curtus) from Penang, Malaysia-Next-Generation Sequencing, Functional Annotation and Toxinological Correlation. Toxins, 13(2), 22. doi: 10.3390/toxins13020127
  18. Tan, C. H., Liew, J. L., Chong, H. P., & Tan, N. H. (2021). Protein decomplexation and proteomics: A complementary assessment method of the physicochemical purity of antivenom. Biologicals, 69, 22-29. doi: 10.1016/j.biologicals.2020.12.004
  19. Tan, C. H., Palasuberniam, P., Blanco, F. B., & Tan, K. Y. (2021). Immunoreactivity and neutralization capacity of Philippine cobra antivenom against Naja philippinensis and Naja samarensis venoms. Transactions of the Royal Society of Tropical Medicine and Hygiene, 115(1), 78-84. doi: 10.1093/trstmh/traa087
  20. Wong, K. Y., Tan, K. Y., Tan, N. H., & Tan, C. H. (2021). A Neurotoxic Snake Venom without Phospholipase A(2): Proteomics and Cross-Neutralization of the Venom from Senegalese Cobra, Naja senegalensis (Subgenus: Uraeus). Toxins, 13(1), 19. doi: 10.3390/toxins13010060
  21. Yong, M. Y., Tan, K. Y., & Tan, C. H. (2021). Potential para-specific and geographical utility of Thai Green Pit Viper (Trimeresurus albolabris) Monovalent Antivenom: Neutralization of procoagulant and hemorrhagic activities of diverse Trimeresurus pit viper venoms. Toxicon, 203, 85-92. doi: 10.1016/j.toxicon.2021.09.021
  22. Chong, H. P., Tan, K. Y., & Tan, C. H. (2020). Cytotoxicity of Snake Venoms and Cytotoxins From Two Southeast Asian Cobras (Naja sumatrana, Naja kaouthia): Exploration of Anticancer Potential, Selectivity, and Cell Death Mechanism. Frontiers in Molecular Biosciences, 7, 16. doi: 10.3389/fmolb.2020.583587
  23. Hia, Y. L., Tan, K. Y., & Tan, C. H. (2020). Comparative venom proteomics of banded krait (Bungarus fasciatus) from five geographical locales: Correlation of venom lethality, immunoreactivity and antivenom neutralization. Acta Tropica, 207, 14. doi: 10.1016/j.actatropica.2020.105460
  24. Lee, L. P., Tan, K. Y., & Tan, C. H. (2020). Toxicity and cross-neutralization of snake venoms from two lesser-known arboreal pit vipers in Southeast Asia: Trimeresurus wiroti and Trimeresurus puniceus. Toxicon, 185, 91-96. doi: 10.1016/j.toxicon.2020.06.012
  25. Liew, J. L., Tan, N. H., & Tan, C. H. (2020). Proteomics and preclinical antivenom neutralization of the mangrove pit viper (Trimeresurus purpureomaculatus, Malaysia) and white-lipped pit viper (Trimeresurus albolabris, Thailand) venoms. Acta Tropica, 209, 15. doi: 10.1016/j.actatropica.2020.105528
  26. Lingam, T. M. C., Tan, K. Y., Tan, C. H. (2020). Proteomics and antivenom immunoprofiling of Russells viper (Daboia siamensis) venoms from Thailand and Indonesia. Journal of Venomous Animals and Toxins Including Tropical Diseases, 26, 17. doi: 10.1590/1678-9199-jvatitd-2019-0048
  27. Pruksaphon, K., Tan, K. Y., Tan, C. H., Simsiriwong, P., Gutierrez, J. M., & Ratanabanangkoon, K. (2020). Anin vitro alpha-neurotoxin-nAChR binding assay correlates with lethality andin vivoneutralization of a large number of elapid neurotoxic snake venoms from four continents. PLoS neglected tropical diseases, 14(8), 21. doi: 10.1371/journal.pntd.0008581
  28. Ratanabanangkoon, K., Tan, K. Y., Pruksaphon, K., Klinpayom, C., Gutierrez, J. M., Quraishi, N. H., & Tan, C. H. (2020). A pan-specific antiserum produced by a novel immunization strategy shows a high spectrum of neutralization against neurotoxic snake venoms. Scientific reports, 10(1), 12. doi: 10.1038/s41598-020-66657-8
  29. Tan, C. H., Liew, J. L., Navanesan, S., Sim, K. S., Tan, N. H., & Tan, K. Y. (2020). Cytotoxic and anticancer properties of the Malaysian mangrove pit viper (Trimeresurus purpureomaculatus) venom and its disintegrin (purpureomaculin). Journal of Venomous Animals and Toxins Including Tropical Diseases, 26, 14. doi: 10.1590/1678-9199-jvatitd-2020-0013
  30. Tan, K. Y., Ng, T. S., Bourges, A., Ismail, A. K., Maharani, T., Khomvilai, S., . . . Tan, C. H. (2020). Geographical variations in king cobra (Ophiophagus hannah) venom from Thailand, Malaysia, Indonesia and China: On venom lethality, antivenom immunoreactivity and in vivo neutralization. Acta Tropica, 203, 7. doi: 10.1016/j.actatropica.2019.105311
  31. Tan, K. Y., Wong, K. Y., Tan, N. H., & Tan, C. H. (2020). Quantitative proteomics of Naja annulifera (sub-Saharan snouted cobra) venom and neutralization activities of two antivenoms in Africa. International Journal of Biological Macromolecules, 158, 605-616. doi: 10.1016/j.ijbiomac.2020.04.173
  32. Chaisakul, J., Alsolaiss, J., Charoenpitakchai, M., Wiwatwarayos, K., Sookprasert, N., Harrison, R. A., . . . Casewell, N. R. (2019). Evaluation of the geographical utility of Eastern Russells viper (Daboia siamensis) antivenom from Thailand and an assessment of its protective effects against venom-induced nephrotoxicity. Plos Neglected Tropical Diseases, 13(10), 27. doi:10.1371/journal.pntd.0007338
  33. Chua, S. S., Lai, P. S. M., Sim, S. M., Tan, C. H., Foong, C. C. (2019). Acceptance of interprofessional learning between medical and pharmacy students in a prescribing skills training workshop: pre-post intervention study. BMC Medical Education, 19, 10. doi:10.1186/s12909-019-1525-y
Others
  1. Faisal, T., Tan, K. Y., Tan, N. H., Sim, S. M., Gnanathasan, C. A., & Tan, C. H. (2021). Proteomics, toxicity and antivenom neutralization of Sri Lankan and Indian Russell s viper (Daboia russelii) venoms. Journal of Venomous Animals and Toxins including Tropical Diseases, 27.
  2. Tan, C. H., & Tan, K. Y. (2021). De Novo Venom-Gland Transcriptomics of Spine-Bellied Sea Snake (Hydrophis curtus) from Penang, Malaysia Next-Generation Sequencing, Functional Annotation and Toxinological Correlation. Toxins, 13(2), 127.
  3. Tan, C. H., Liew, J. L., Chong, H. P., & Tan, N. H. (2021). Protein decomplexation and proteomics: A complementary assessment method of the physicochemical purity of antivenom. Biologicals. (in press)
  4. Tan, C. H., Palasuberniam, P., Blanco, F. B., & Tan, K. Y. (2021). Immunoreactivity and neutralization capacity of Philippine cobra antivenom against Naja philippinensis and Naja samarensis venoms. Transactions of the Royal Society of Tropical Medicine and Hygiene, 115, 78-84.
  5. Tan, C.H.; Tan, K.Y. De Novo Venom-Gland Transcriptomics of Spine-Bellied Sea Snake (Hydrophis curtus) from Penang, Malaysia Next-Generation Sequencing, Functional Annotation and Toxinological Correlation. Toxins 2021, 13, 127. https://doi.org/10.3390/toxins13020127
  6. Wong, K.Y.; Tan, K.Y.; Tan, N.H.; Tan, C.H. (2021) A Neurotoxic Snake Venom without Phospholipase A2: Proteomics and Cross-Neutralization of the Venom from Senegalese Cobra, Naja senegalensis (Subgenus: Uraeus). Toxins, 13, 60.
  7. Chong, H. P., Tan, K. Y., & Tan, C. H. (2020). Cytotoxicity of Snake Venoms and Cytotoxins From Two Southeast Asian Cobras (Naja sumatrana, Naja kaouthia): Exploration of Anticancer Potential, Selectivity, and Cell Death Mechanism. Frontiers in Molecular Biosciences, 7.
  8. Hia, Y. L., Tan, K. Y., Tan, C. H. (2020) Comparative venom proteomics of banded krait (Bungarus fasciatus) from five geographical locales: Correlation of venom lethality, immunoreactivity and antivenom neutralization. Acta Trop, 207, 105460.
  9. Lee, L. P., Tan, K. Y., & Tan, C. H. (2020). Toxicity and cross-neutralization of snake venoms from two lesser-known arboreal pit vipers in Southeast Asia: Trimeresurus wiroti and Trimeresurus puniceus. Toxicon 185, 91-96.
  10. Liew, J. L., Tan, N. H., Tan, C. H. (2020) Proteomics and preclinical antivenom neutralization of the mangrove pit viper (Trimeresurus purpureomaculatus, Malaysia) and white-lipped pit viper (Trimeresurus albolabris, Thailand) venoms. Acta Trop, in press, doi: 10.1016/j.actatropica.2020.105528.
  11. Lingam, T. M. C., Tan, K. Y., Tan, C. H. (2020) Proteomics and antivenom immunoprofiling of Russell s viper (Daboia siamensis) venoms from Thailand and Indonesia. Journal of Venomous Animals and Toxins including Tropical Diseases, 26, e20190048.
  12. Pruksaphon, K., Tan, K. Y., Tan, C. H., Simsiriwong, P., Guti rrez, J. M., & Ratanabanangkoon, K. (2020). An in vitro -neurotoxin-nAChR binding assay correlates with lethality and in vivo neutralization of a large number of elapid neurotoxic snake venoms from four continents. PLoS neglected tropical diseases, 14(8), e0008581.
  13. Ratanabanangkoon, K., Tan, K. Y., Pruksaphon, K., Klinpayom, C., Gutierrez, J. M., Quraishi, N. H, Tan, C.H. (2020). A pan-specific antiserum produced by a novel immunization strategy shows a high spectrum of neutralization against neurotoxic snake venoms. Scientific Reports 10, 1-12.
  14. Tan, C. H., Liew, J. L., Navanesan, S., Sim. K. S., Tan, N. H., Tan, K. Y. (2020) Cytotoxic and anticancer properties of the Malaysian mangrove pit viper (Trimeresurus purpureomaculatus) venom and its disintegrin (purpureomaculin). Journal of Venomous Animals and Toxins including Tropical Diseases 26.
  15. Tan, K. Y., Ng, T. S., Bourges, A., Ismail, A. K., Maharani, T., Khomvilai, S., Sitprija, V., Tan, N. H., Tan, C. H. (2020) Geographical variations in king cobra (Ophiophagus hannah) venom from Thailand, Malaysia, Indonesia and China: On venom lethality, antivenom immunoreactivity and in vivo neutralization. Acta Tropica, 203, 105311.
  16. Tan, K. Y., Wong, K. Y., Tan, N. H., Tan, C. H. (2020) Quantitative proteomics of Naja annulifera (sub-Saharan snouted cobra) venom and neutralization activities of two antivenoms in Africa. Int J Biol Macromol., 158, 605-616.
  17. Chaisakul, J., Alsolaiss, J., Charoenpitakchai, M., Wiwatwarayos, K., Sookprasert, N., Harrison, R.A., Chaiyabutr, N., Chanhome, L., Tan, C. H., Casewell, N. R. (2019) Evaluation of the geographical utility of Eastern Russell's viper (Daboia siamensis) antivenom from Thailand and an assessment of its protective effects against venom-induced nephrotoxicity. PLOS Neglected Tropical Diseases 13(10): e0007338.
  18. Chong, H. P., Tan, K. Y., Tan, N. H., & Tan, C. H. (2019). Exploring the diversity and novelty of toxin genes in Naja sumatrana, the Equatorial spitting cobra from Malaysia through de novo venom-gland transcriptomics. Toxins, 11(2), 104.
  19. Esther Lai Har Tang, Nget Hong Tan, Shin Yee Fung, Choo Hock Tan (2019). Comparative proteomes, immunoreactivities and neutralization of procoagulant activities of Calloselasma rhodostoma (Malayan pit viper) venoms from four regions in Southeast Asia. Toxicon.
  20. Lingam, T. M. C., Tan, K. Y., & Tan, C. H. (2019). Thai Russell's viper monospecific antivenom is immunoreactive and effective in neutralizing the venom of Daboia siamensis from Java, Indonesia. Toxicon 168, 95-97.
  21. Oh, A. M. F., Tan, C. H., Tan, K. Y., Quraishi, N. A., & Tan, N. H. (2019). Venom proteome of Bungarus sindanus (Sind krait) from Pakistan and in vivo cross-neutralization of toxicity using an Indian polyvalent antivenom. Journal of Proteomics, 193, 243-254.
  22. Tan, C. H., Tan, K. Y., Ng, T. S., Quah, E. S., Ismail, A. K., Khomvilai, S., Sitprija, V., & Tan, N. H. (2019). Venomics of Trimeresurus (Popeia) nebularis, the Cameron Highlands Pit Viper from Malaysia: Insights into Venom Proteome, Toxicity and Neutralization of Antivenom. Toxins, 11(2), 95.
  23. Tan, C. H., Tan, K. Y., Ng, T. S., Sim, S. M., & Tan, N. H. (2019). Venom proteome of spine-bellied sea snake (Hydrophis curtus) from Penang, Malaysia: Toxicity correlation, immunoprofiling and cross-neutralization by sea snake antivenom. Toxins (Basel), 11(1), 3.
  24. Tan, C. H., Wong, K. Y., Chong, H. P., Tan, N. H., Tan, K. Y. (2019) Proteomic insights into short neurotoxin-driven, highly neurotoxic venom of Philippine cobra (Naja philippinensis) and toxicity correlation of cobra envenomation in Asia. Journal of Proteomics, 206, 103418.
  25. Tan, C. H., Wong, K. Y., Tan, N. H., Ng, T. S., & Tan, K. Y. (2019). Distinctive distribution of secretory phospholipases A2 in the venoms of Afro-Asian cobras (Subgenus: Naja, Afronaja, Boulengerina and Uraeus). Toxins, 11(2), 116.
  26. Tan, K. Y., Liew, J. L., Tan, N. H., Quah, E. S. H., Ismail, A. K., & Tan, C. H. (2018). Unlocking the secrets of banded coral snake (Calliophis intestinalis, Malaysia): A venom with proteome novelty, low toxicity and distinct antigenicity. Journal of Proteomics. 192, 246-257.
  27. Faisal, T., Tan, C.H., Tan, K.Y., Sim, S.M., Quraishi,N. and Tan, N.H. (2018). Proteomics, Functional Characterization and Antivenom Neutralization of the Venom of Pakistani Russell's Viper (Daboia russelii) from the Wild. J Proteomics 183: 1-13.
  28. Ratanabanangkoon, K., Simsiriwong, P., Pruksaphon, K., Tan, K. Y., Chantrathonkul, B., Eursakun, S., & Tan, C. H. (2018). An in vitro potency assay using nicotinic acetylcholine receptor binding works well with antivenoms against Bungarus candidus and Naja naja. Scientific reports, 8(1), 9716.
  29. Tan, K. Y., Tan, N. H., & Tan, C. H. (2018). Venom proteomics and antivenom neutralization for the Chinese eastern Russell s viper, Daboia siamensis from Guangxi and Taiwan. Scientific Reports, 8(1), 8545.
  30. Wong, K. Y.; Tan, C. H.; Tan; Tan, K. Y.; Quraishi, N. H.; Tan, N. H. (2018) Elucidating the biogeographical variation of the venom of Naja naja (spectacled cobra) from Pakistan through a venom-decomplexing proteomic study. J Proteomics. 175, 156-173.
  31. Wong, K. Y.; Tan, C. H.; Tan; Tan, K. Y.; Quraishi, N. H.; Tan, N. H. (2018) Elucidating the biogeographical variation of the venom of Naja naja (spectacled cobra) from Pakistan through a venom-decomplexing proteomic study. J Proteomics. 175, 156-173.
  32. Oh, A. M. F., Tan, C. H., Ariaranee, G. C., Quraishi, N., & Tan, N. H. (2017). Venomics of Bungarus caeruleus (Indian krait): Comparable venom profiles, variable immunoreactivities among specimens from Sri Lanka, India and Pakistan. J Proteomics, 164, 1-18.
  33. Ratanabanangkoon, K., Simsiriwong, P., Pruksaphon, K., Tan, K. Y., Eursakun, S., Tan, C. H., Chantrathonkul, B., Wongwadhunyoo, W., Youngchim, S., Tan, N. H. (2017). A novel in vitro potency assay of antisera against Thai Naja kaouthia based on nicotinic acetylcholine receptor binding. Sci Rep, 7(1), 8545.
  34. Tan, C. H., Liew, J. L., Tan, N. H., Ismail, A. K., Maharani, T., Khomvilai, S., Sitprija, V. (2017) Cross reactivity and lethality neutralization of venoms of Indonesian Trimeresurus complex species by Thai Green Pit Viper Antivenom. Toxicon 16;140:32-37. doi: 10.1016/j.toxicon.2017.10.014
  35. Tan, C. H., Tan, K. Y., Yap, M. Y. K. K., Tan, N. H. (2017) Venomics of Tropidolaemus wagleri, the sexually dimorphic temple pit viper: Unveiling a deeply conserved atypical toxin arsenal. Scientific Reports 7: 43237. doi:10.1038/srep43237
  36. Tan, C. H., Wong, K. Y., Tan, K. Y., & Tan, N. H. (2017). Venom proteome of the yellow-lipped sea krait, Laticauda colubrina from Bali: Insights into subvenomic diversity, venom antigenicity and cross-neutralization by antivenom. Proteomics, 166, 48-58.
  37. Tan, K. Y., Tan, C. H., Chanhome, L., & Tan, N. H. (2017). Comparative venom gland transcriptomics of Naja kaouthia (monocled cobra) from Malaysia and Thailand: elucidating geographical venom variation and insights into sequence novelty. PeerJ, 5, e3142.
  38. Tan, K. Y., Tan, C. H., Chanhome, L., & Tan, N. H. (2017). Comparative venom gland transcriptomics of Naja kaouthia (monocled cobra) from Malaysia and Thailand: elucidating geographical venom variation and insights into sequence novelty. PeerJ, 5, e3142.
  39. Tan, N. H., Wong, K. Y., Tan C. H. (2017) Venomics of Naja sputatrix, the Javan spitting cobra: A short neurotoxin-driven venom needing improved antivenom neutralization. J Proteomics, 157: 18-32. http://dx.doi.org/10.1016/j.jprot.2017.01.018
  40. Choo Hock Tan, Shin Yee Fung, Michelle Khai Khun Yap, Poh Kuan Yap, Jia Lee Liew, Nget Hong Tan (2016). Unveiling the elusive and exotic: Venomics of the Malayan blue coral snake (Calliophis bivirgata flaviceps). Journal of Proteomics 132:1-12
  41. Esther Tang Li Har, Choo Hock Tan, Shin Yee Fung, Nget Hong Tan. 2016. Venomics of Calloselasma rhodostoma, the Malayan pit viper : A complex toxin arsenal unraveled. Journal of Protoemics, 148, 44-56.
  42. K.Y. Tan; C.H., Tan; S.Y. Fung; N.H. Tan. (2016) Neutralization of the Principal Toxins from the Venoms of Thai Naja kaouthia and Malaysian Hydrophis schistosus: Insights into Toxin-Specific Neutralization by Two Different Antivenoms. Toxins 8(4), 86; doi:10.3390/toxins8040086
  43. Ratanabanangkoon K, Tan KY, Eursakun S, Tan CH, Simsiriwong P, Pamornsakda T, Wiriyarat W, Klinpayom C, Tan NH. (2016) A Simple and Novel Strategy for the Production of a Pan-specific Antiserum against Elapid Snakes of Asia. PLoS Negl Trop Dis. 10(4):e0004565. doi: 10.1371/journal.pntd.0004565.
  44. Tan, C. H., Liew, J. L., Tan, K. Y., Tan, N. H. (2016) Assessing SABU (Serum Anti Bisa Ular), the sole Indonesian antivenom: A proteomic analysis and neutralization efficacy study. Sci Rep. 6: 37299. doi:10.1038/srep37299
  45. Tan, C. H.; Liew, J. L.; Tan, K. Y.; Tan, N. H. (2016) Genus Calliophis of Asiatic coral snakes: A deficiency of venom cross-reactivity and neutralization against seven regional elapid antivenoms. Toxicon 121:130-133.
  46. Tan, C.H., Tan, K.Y., Tan, N.H. 2016. Revisiting Notechis scutatus venom: on shotgun proteomics and neutralization by the bivalent Sea Snake Antivenom. Journal of Proteomics 144: 33-38.
  47. Tan, K. Y., Tan, C. H., Fung, S. Y., & Tan, N. H. (2016). Neutralization of the principal toxins from the venoms of Thai Naja kaouthia and Malaysian Hydrophis schistosus: insights into toxin-specific neutralization by two different antivenoms. Toxins, 8(4), 86.
  48. Tan, K.Y.; Tan, C.H.; Sim, S.M.; Fung, S.Y.; Tan, N.H. (2016) Geographical venom variations of the Southeast Asian monocled cobra (Naja kaouthia): venom-induced neuromuscular depression and antivenom neutralization. Comp Biochem Physiol C Toxicol Pharmacol. 185-186:77-86. doi: 10.1016/j.cbpc.2016.03.005.
  49. Wong, K.Y.; Tan, C.H.; Tan, N.H. Venom and purified toxins of the spectacled cobra (Naja naja) from Pakistan: Insights into toxicity and antivenom neutralization. Am. J. Trop. Med. Hyg. 2016. doi: 10.4269/ajtmh.15-0871
  50. Lai, P. S. M., Sim, S. M., Chua, S. S., Tan, C. H., Ng, C. J., Achike, F. I. and Teng, C. L. (2015). "Development and validation of an instrument to assess the prescribing readiness of medical students in Malaysia." BMC Med Educ 15: 153.
  51. Lai, P.S.M.. Sim, S.M., Chua, S.S., Tan, C.H., Ng, C.J., Achike, F.I. & Teng, C.L. 2015. Development and validation of an instrument to assess the prescribing readiness of medical students in Malaysia. BMC Medical Education 15:153 (11 pages), doi: 10.1186/s12909-015-0433-z.
  52. Leong, P.K., Fung, S.Y., Tan, C.H., Sim, S.M., Tan, N.H. (2015) Immunological cross-reactivity and neutralization of the principal toxins of Naja sumatrana and related cobra venoms by a Thai polyvalent antivenom (Neuro Polyvalent Snake Antivenom). Acta Trop. doi: 10.1016/j.actatropica.2015.05.020. Epub 2015 May 27
  53. Tan, C. H., Tan, N. H., Sim, S. M., Fung, S. Y., Gnanathasan, C. A. (2015) Proteomic investigation of Sri Lankan hump-nosed pit viper (Hypnale hypnale) venom. Toxicon 93C, 164-170
  54. Tan, C. H., Tan, N. H., Tan, K. Y.,Kwong, K. O. (2015) Antivenom Cross-Neutralization of the Venoms of Hydrophis schistosus and Hydrophis curtus, Two Common Sea Snakes in Malaysian Waters. Toxins 7(2), 572-581
  55. Tan, C.H., Tan, K.Y., Fung, S.F., Tan, N.H. Venom-gland transcriptome and venom proteome of the Malaysian king cobra (Ophiophagus hannah). (2015) BMC Genomics 16(1):687
  56. Tan, C.H., Tan, K.Y., Lim, S.E., Tan, N.H. (2015) Venomics of the beaked sea snake, Hydrophis schistosus: A minimalist toxin arsenal and its cross-neutralization by heterologous antivenoms. J Proteomics 126:121-130.
  57. Tan, K. Y., Tan, C. H., Fung, S. Y., Tan, N. H. (2015) Venomics, lethality and Neutralization of Naja kaouthia (monocled cobra) venoms from three different geographical regions of Southeast Asia. Journal of Proteomics, accepted for publication.
  58. Tan, K.Y., Tan, C.H. Fung, S.Y. and Tan, N.H. (2015). Venomics, lethality and neutralization of Naja kaouthia (monocled cobra) venoms from three different geographical regions of Southeast Asia. J. Proteomics, 120:105-125. doi: 10.1016/j.jprot.2015.02.012
  59. Tan, N.H.*, Fung, S.Y., Tan, K.Y., Yap, M.K.K., Gnanathasan, C.A., Tan, C.H.* (2015) Functional venomics of the Sri Lankan Russell's viper (Daboia russelii) and its toxinological correlations. J Proteomics 128:403-23
  60. Yap, M.K.K., Tan, N.H., Sim, S.M., Fung,S.Y., Tan, C.H. (2015). The effect of polyvalent antivenom on the pharmacokinetics of Naja sputatrix (Javan spitting cobra) venom in experimentally envenomed rabbits. Basic & Clinical Pharmacology & Toxicology (accepted for publication)
  61. Leong, P. K., Tan, C. H., Sim, S. M., Fung, S. Y., Sumana, K., Sitprija, V., Tan, N. H. (2014). Cross neutralization of common Southeast Asian viperid venoms by a Thai polyvalent snake antivenom (Hemato Polyvalent Snake Antivenom). Acta Trop. 132:7-14.
  62. Sim, S. M., Foong, C. C., Tan, C. H., Lai, P. S. M., Chua, S. S. and Mohazmi, M. (2014). "The use of jigsaw learning technique in teaching medical students prescribing skills." Medical Teacher 36(2): 182-182.
  63. Tan, C. H., Sim, S. M., Gnanathasan, C. A., Fung, S. Y., Tan, N. H. (2014). Pharmacokinetics of the Sri Lankan hump-nosed pit viper (Hypnalehypnale) venom following intravenous and intramuscular injections of the venom into rabbits.Toxicon.79:37-44.
  64. Yap MKK, Tan NH, Sim SM, Fung SY, Tan CH (2014) Pharmacokinetics of Naja sumatrana (Equatorial Spitting Cobra) Venom and Its Major Toxins in Experimentally Envenomed Rabbits. PLoS Negl Trop Dis 8(6): e2890. doi:10.1371/journal.pntd.0002890
  65. Tan, C. H., Tan, N. H., Sim, S. M., Fung, S. Y., Pailoor, J., & Gnanathasan, C. A. (2012). Nephrotoxicity of hump-nosed pit viper (Hypnale hypnale) venom in mice is preventable by the paraspecific Hemato polyvalent antivenom (HPA). Toxicon, 60(7), 1259-1262. doi: 10.1016/j.toxicon.2012.08.012
  66. Tan, C.H., Tan, N.H.,Sim, S.M., Fung, S.Y. and Gnanathasan, C.A. (2012). Immunological properties of Hypnale hypnale (hump-nosed pit viper) venom: Antibody production with diagnostic and therapeutic potentials. Acta Tropica, 122, 267-275.
  67. Tan, C. H., Leong, P.K., Fung, S.Y., Sim, S.M., Ponnudurai, G., Ariaratnam, C., Khomvilai, S., Sitprija, V., & Tan, N.H. (2011). Cross neutralization of Hypnale hypnale (hump-nosed pit viper) venom by polyvalent and monovalent Malayan pit viper antivenoms in vitro and in a rodent model. Acta Trop., 117(2), 119-124. doi: 10.1016/j.actatropica.2010.11.001
  68. Tan, C. H., Sim, S. M., Gnanathasan, C. A., Fung, S. Y., Ponnudurai, G., Pailoor, J., & Tan, N. H. (2011). Enzymatic and toxinological activities of Hypnale hypnale (hump-nosed pit viper) venom and its fractionation by ion exchange high performance liquid chromatography. J. Venom Anim. Toxins incl. Trop. Dis., 17(4), 473-485. doi: 10.1590/S1678- 91992011000400015
Chapter in Books
  1. Tan, N.H., Tan, K.Y., Tan, C.H. (2021) Snakebite in Southeast Asia. Envenomation and Clinical Management. In: Mackessy, S.P. (Ed.) Handbook of Venoms and Toxins of Reptiles (2nd ed.), 559-579. CRC Press, Boca Raton.
  2. Sim, D.S.M., Tan, C.H., Amir, A. (2020) To change or not to change - Moving from traditional teaching to problem-based learning at University Malaya medical school. In Shahbodin, F, & Jano, Z., Problem Based Learning: Best Practices, Research and Development (pp. 93-104). University Press, Universiti Teknikal Malaysia Melaka.
  3. Tan, C. H., & Tan, K. Y. (2019). Functional Application of Snake Venom Proteomics in In Vivo Antivenom Assessment. In X. Wang & M. Kuruc (Eds.), Functional Proteomics: Methods and Protocols (pp. 153-158). New York, NY: Springer New York.
  4. Tan, C. H., Tan, K. Y., & Tan, N. H. (2019). A Protein Decomplexation Strategy in Snake Venom Proteomics. In X. Wang & M. Kuruc (Eds.), Functional Proteomics: Methods and Protocols (pp. 83-92). New York, NY: Springer New York.
  5. Tan, C. H. & Amir A. (2018) Enhancing student learning through problem-based learning. In: Sim, J.H., Foong, C.C., Hong, W.H., Pallath, V., & Vadivelu, J. (Eds.). (2018). Enhancing student learning in medical schools. Kuala Lumpur, Malaysia: University of Malaya Press.
  6. Tan, N. H. and Tan, C. H. (2016) Cytotoxicity of snake venoms and toxins: Mechanisms and applications. In Utkin, Y. N. & Krivoshein, A. V. (Eds.), Snake Venoms and Envenomation. Modern Trends and Future Prospects (pp. 217-253). New York, NY: Nova Science Publishers
  7. Chua SS, Sim SM, Mohamed M, Lai PSM, Tan CH. Report regarding Interprofessional Education in a Pharmacy Context in University of Malaya, Malaysia. In: Bruno A, editor. Interprofessional Education in a Pharmacy Context: A Global report: International Pharmaceutical Federation; 2015. p. 28-9
  8. Sim, S. M., Tan, C. H. (2014) Drug interaction. In: Chan, Y.K., Ng, K.P. & Sim, D.S.M. (eds.). Pharmacological Basis of Acute Care. Chapter 10, Pg 81-86. Switzerland: Springer International Publishing.
  9. Tan, C. H. (2014) Dose Response Relationship. In: Chan, Y.K., Ng, K.P. & Sim, D.S.M. (eds.). Pharmacological Basis in Acute Care. Chapter 7, Pg 57-64. Switzerland: Springer International Publishing.
  10. Tan, C. H., Ismail, A. K. (2014) The poisoned patient. In: Chan, Y.K., Ng, K.P. & Sim, D.S.M. (eds.). Pharmacological Basis in Acute Care. Chapter 27, Pg 219-225. Switzerland: Springer International Publishing.
  11. Tan, C. H.; Tan, N. H. (2015) Toxinology of Snake Venoms: The Malaysian Context. In: Gopalakrishnakone et al. (Eds) Toxinology Series - Snake Venoms. Pg 1-37. Springer, Switzerland.
Article in Proceeding
  1. Choo Hock Tan, Kae Yi Tan, Sin Ee Lim (corrected name replacing previous error), Nget Hong Tan (2015) Venomics of Hydrophis schistosus, the beaked sea snake: a simple toxin arsenal cross-neutralised by two heterologous antivenoms. In: Proceedings of the 18th IST World Congress on Toxinology, Oxford University, United Kingdom, 25 Sep - 30 Sep (28-3-20, p. 113). Oxford, United Kingdom: Oxford University.
  2. Si Mui Sim, Mohazmi bin Mohamed, Choo Hock Tan, Siew Siang Chua, Pauline Siew Mei Lai, Sajaratulnisah binti Othman and Francis Ifejika Achike. 2010. Filling the Gap:From pharmacology lectures to bedside prescribing. 7th International Medical Education Conference (IMEC- 2010), Malaysia. OC-17, pp 32
  3. Fung Shin Yee, Tan Nget Hong, Tan Choo Hock, Sim Si Mui.2009. Pathway Analysis of differently expressed genes in heart of rat injected with lethal dose of naja sputatrix (Malayan cobra) snake venom. 18th Scientific Meeting of the Malaysian Society for Molecular Biology and Biotechnology, PP015, pp.39

RESEARCH INTEREST


  • Molecular profiling of toxins and genes: Venom proteomics and venom-gland transcriptomics
  • Toxinological and immunological charactetisations of snake venoms
  • Antivenom profilings for efficacy assessment and optimisation
  • Problem-based learning in medical education
  • Prescribing skills training in medical graduates and junior doctors
  • Adverse drug reactions: phenotyping and genotyping studies

RESEARCH PROJECT


National
  1. 2017 - 2018, NONE
    EVALUATING THE PRESCRIBING READINESS OF MEDICAL STUDENTS IN MALAYSIA USING THE PRESCRIBING INITIATIVES FOR LIFELONG LEARNING (PILL) ( Consultant)
  2. 2013 - 2015, High Impact Research (HIR)
    Pharmocogenomics of Adverse Drug Reactions: Focus on Anti-tuberculosis Drug Induced Liver Injury (AT-DILI) ( Consultant)
  3. 2012 - 2014, Geran Penyelidikan Universiti Malaya (UMRG)
    Pharmacokinetic of bioactive substance from medically important Asiatic viperid venoms ( Consultant)
  4. 2011 - 2013, Postgraduate Research Grant(PPP)
    BIOMEDICAL AND PROTEOMIC CHARACTERIZATION OF SNAKE VENOMS WITH CLINICAL IMPORTANCE AND THERAPEUTIC POTENTIALS ( Consultant)
  5. 2009 - 2012, Geran Penyelidikan Universiti Malaya (UMRG)
    Pharmacological characterisation of the protective activity of Mucuna pruriens seed against the cardiovascular and neuromuscular depressant effects of snake venoms ( Consultant)
  6. 2010 - 2011, Postgraduate Research Grant(PPP)
    Biomedical characterisation of the venom of hump- nosed pit viper (Hypnale hypnale) ( Consultant)

CONSULTANCY PROJECT


  • External Examiner for Master of Medical Sciences (by Research), Lincoln University College
    01 Dec 2020 - 01 Dec 2023 (National)
  • Panel of Expert (Poe) for First-in-Human (Fih) Clinical Investigations, National Pharmaceutical Regulatory Agency (NPRA)
    01 Dec 2020 - 01 Dec 2022 (National)
  • Scientist Resource Person and Scientific Committee Member for Institutional Animal Care and Use Committee, Faculty of Medicine, University of Malaya, Univesity of Malaya
    01 Dec 2018 - 01 Dec 2020 (National)
  • Interprofessional Prescribing Skills (Pill-1) Training Workshop for Medical and Pharmacy Students 2018-2019, Faculty of Medicine, University of Malaya
    01 Dec 2018 - 01 Dec 2019 (National)
  • Prescribing Skills Training Workshop, MBBS Phase Iiib, Session 2014/2015, 6th August 2014, Faculty of Medicine, University of Malaya
    01 Dec 2014 - 01 Dec 2014 (National)
  • Pbl Training Workshop At The College of Health Sciences, Ummc, University of Malaya, 15 & 18 December 2014, Kolej Sains Kesihatan, PPUM
    01 Dec 2014 - 01 Dec 2014 (National)
  • International Workshop On Advanced Management of Marine Animals & Snake Envenomation in Malaysia, 4-5 June 2013, Malaysian Society on Toxinology
    01 Dec 2014 - 01 Dec 2014 (International)
  • Problem Based Learning (Pbl) Tutor Training Workshop for Ummp, 21st 24th October 2013, MERDU, Faculty of Medicine, University of Malaya
    01 Mar 2013 - 01 Mar 2013 (National)
  • Bengkel Designing Triggers for Problem Based Learning, 7 Mei 2013, Pusat Pembangunan Akademik (ADeC), Univerity of Malaya
    01 Mar 2013 - 01 Mar 2013 (National)
  • Bengkel Latihan Problem Based Learning (Pbl), 25 & 30 April 2013, MERDU, Faculty of Medicine, University of Malaya
    01 Mar 2013 - 01 Mar 2013 (National)
  • International Workshop On Advanced Management of Marine Animals & Snake Envenomation in Malaysia, 4-5 June 2013, AMSEM
    01 Mar 2013 - 01 Mar 2013 (International)
  • National Workshop On Advanced Management of Marine Animals & Snake Envenomation in Malaysia, 29-30 May 2012, AMSEM
    01 Mar 2012 - 01 Mar 2012 (National)
  • Bengkel Latihan Problem Based Learning (Pbl), 27 Nov & 3 Dec 2012, MERDU, Faculty of Medicine, University of Malaya
    01 Mar 2012 - 01 Mar 2012 (National)
  • Prescribing Skills Training Workshop, MBBS Phase Iiib, Session 2011/2012, 3 August 2011, Faculty of Medicine, University of Malaya
    01 Mar 2011 - 01 Mar 2011 (National)
  • Bengkel Latihan Problem Based Learning (Pbl), 3 & 9 Mac 2011, Dean's Office, Faculty of Medicine
    01 Mar 2011 - 01 Mar 2011 (National)
  • Prescribing Skills Training Workshop, MBBS Phase Iiib, Session 2011/2012, 17 August 2011, Faculty of Medicine, University of Malaya
    01 Mar 2011 - 01 Mar 2011 (National)
  • Prescribing Skills Training Workshop, MBBS Phase Iiib, Session 2011/2012, 7 November 2011, Faculty of Medicine, University of Malaya
    01 Mar 2011 - 01 Mar 2011 (National)
  • Prescribing Skills Training Workshop, MBBS Phase Iiib, Session 2010/2011, 22 September 2010, PILLS Project Team, Dept of Pharmacology, FOM, UM
    01 Mar 2010 - 01 Mar 2010 (National)
  • Problem Based Learning Workshop 2010 (for Training Medical Students and Tutors from All Disciplines), 21-23 July 2010, Faculty of Medicine and Health Sciences jointly with CALM, University of Malaysia Sarawak. Kuching.
    01 Mar 2010 - 01 Mar 2010 (National)
  • Bengkel Latihan Problem Based Learning (Pbl), 11 & 17th Mac 2010, Dean's Office, Faculty of Medicine, University of Malaya
    01 Mar 2010 - 01 Mar 2010 (National)
  • Bengkel Latihan Problem Based Learning (Pbl), 6 & 11 October 2010, Dean's Office, Faculty of Medicine
    01 Mar 2010 - 01 Mar 2010 (National)
  • Pbl Tutor Training Workshop for Dental and Other Health Professionals, 22-23 Jan 2010, Faculty of Dentistry, UiTM, Shah Alam.
    01 Mar 2010 - 01 Mar 2010 (National)
  • Prescribing Skills Training Workshop, MBBS Phase Iiib, Session 2010/2011, 24 November 2010, PILLS Project Team, Dept of Pharmacology, FOM, UM
    01 Mar 2010 - 01 Mar 2010 (National)
  • Prescribing Skills Training Workshop, MBBS Phase Iiib, Session 2010/2011, 29 September 2010, PILLS Project Team, Dept of Pharmacology, FOM, UM
    01 Mar 2010 - 01 Mar 2010 (National)
  • Prescribing Skills Training Workshop, MBBS Phase Iiib, Session 2010/2012, 29 September 2010, PILLS Project Team, Dept of Pharmacology, FOM, UM
    01 Mar 2010 - 01 Mar 2010 (National)
  • Bengkel Latihan Problem Based Learning (Pbl), 8 & 13 2009, Dean's Office, Faculty of Medicine, University of Malaya
    01 Mar 2009 - 01 Mar 2009 (National)

PAPER PRESENTED


PLENARY SPEAKER
  1. Mapping snake venomics: Insights into biomedical and evolutionary significance of snake toxins., 19th World Congress of Toxinology, Hainan University and International Society on Toxinology (International) (24 Oct 2017 - 31 Oct 2017)
  2. Snake Venom and Antivenom, The 4th International Symposium on ASEAN Marine Animals & Snake Envenoming (Poisoning) Management, AMSEM 2016, Malaysian Society on Toxinology (International) (28 Nov 2016 - 01 Dec 2016)
  3. Toxicological and immunological characterization of the Sri Lanka hump-nosed pit viper (Hypnale hypnale) venom, in: Constantine, G.R. (Ed.), Univerisity of Colombo Annual Research Symposium. (Proceedings of the 2011 Annual Research Symposium of the University of Colombo, Colombo, Sri Lanka). Proceedings, p. 219-220., Univerisity of Colombo Annual Research Symposium 2011, University of Colombo (International) (28 Jun 2011 - 29 Jun 2011)
INVITED SPEAKER
  1. Neutralization of the Eastern Russell s viper (Daboia siamensis) venom: geographical utility of the Taiwanese Russell s viper monovalent antivenom, International Workshop-Symposium for Clinical Toxicology 2019 , National Poison Center and Taipei Veterans General Hospita (International) (14 Nov 2019 - 17 Nov 2019)
  2. Pharmacokinetics and Pharmacodynamics of snake venom toxins and the interplay between venom and antivenom, International Workshop-Symposium for Clinical Toxicology 2019, National Poison Center and Taipei Veterans General Hospita (International) (14 Nov 2019 - 17 Nov 2019)
  3. Biomedical Profiling of Snake Venoms and Antivenoms, Asia Pacific Association of Medical Toxicology 2019 Pre-conference workshop on Snakebite Envenomation and Research , Asia Pacific Association of Medical Toxicology, National Poison Centre of Malaysia, Malaysian Society on Toxinology (International) (04 Nov 2019 - 04 Nov 2019)
  4. Insights into the evolutionary and medical significance of unique alpha-neurotoxin and phospholipase A2 compositions in Naja spp. (cobra) venoms, 19th World Congress of International Society on Toxinology (IST 2019), International Society on Toxinology (International) (08 Sep 2019 - 13 Sep 2019)
  5. Overview of venomics and antivenomics: Technologies and applications, International Conference on Advanced Molecular Bioscience and Bioengineering (ICAMBEE 2019) Post-Conference Workshop, Brawijaya Unniversity (International) (28 Aug 2019 - 29 Aug 2019)
  6. Snake venom research: Regional context, current and future challenges , International Conference on Advanced Molecular Bioscience and Bioengineering (ICAMBEE 2019) Post-Conference Seminar, Brawijaya University (International) (28 Aug 2019 - 29 Aug 2019)
  7. Bioprospecting snake venom toxins in diagnostics, antivenom innovation and drug discovery , International Conference on Advanced Molecular Biosciences and Bioengineering , Brawijaya University, Malang, Java, Indonesia (International) (27 Aug 2019 - 28 Aug 2019)
  8. Stepping up toward better snakebite treatment and drug discovery through proteomics and transcriptomics of snake venoms, International Symposium on Integrative Organismal Biology: Integrating structural biology with "omics" in Asia Pacific, College of Life Sciences, Natonal Tsing Hua Univesity, Hsinchu, Taiwan (International) (05 Jun 2019 - 06 Jun 2019)
  9. Functional proteomics and transcriptomics in deep profiling of snake venoms: Toward improved snakebite treatment and discovery of novel bioactive molecules, Academia Sinica Symposium, Acamia Sinica, Taipei, Taiwan (International) (03 Jun 2019 - 04 Jun 2019)
  10. Appreciating expired snake antivneoms: a plausible alternative solution to overcome antivenom shortage, 19th World Congress of the International Society on Toxinology, Hainan University and International Society on Toxinology (International) (24 Oct 2017 - 31 Oct 2017)
  11. Overview of protein decomplexation and -omics strategies , Protein profiling through decomplexation and omics strategies. , VETOX Laboratory, Department of Pharmacology, and Department of Molecular Medicine, University of Malaya (University) (16 Oct 2017 - 17 Oct 2017)
  12. Essentials and medical importance of snake venoms: The Southeast Asian Context, The 4th International Sympoium on ASEAN Marine Animals & Snake Envenoming (Poisoning) Management AMSEM 2016, Malaysian Society on Toxinology and University of Science Malaysia (International) (28 Nov 2016 - 01 Dec 2016)
  13. Elucidating geographical variation of snake venoms: Toward the optimization of antivenom use, Indian National Seminar on Snake Venom Research and Snakebite Therapy: National and International Perspectives (SnakSymp 2016) and Toxinological Society of India Meeting, Tezpur University and The Toxinological Society of India (International) (22 Nov 2016 - 24 Nov 2016)
  14. Working through muscle twitches: Short case discussion, Seminar and Workshop on Neuromuscular Pharmacology & Nerve-Muscle Preparation, Venom & Toxin Research Laboratory, Department of Pharmacology, Faculty of Medicine, University of Malaya (University) (02 Nov 2016 - 04 Nov 2016)
  15. Pharmacology of Antivenom, An Essential Introduction to Snakes, Venom and Envenomation, UiTM and the Malaysian Society on Toxinology (National) (30 Sep 2016 - 30 Sep 2016)
  16. Venomics, toxin purification and neutralization: An South Asian perspective towards the optimisation of antivenom management, Toxinology Society of India Conference 2015, Toxinology Society of India and Little Flower Hospital (International) (21 Nov 2015 - 22 Nov 2015)
  17. Snake venom: the bite that kills and heals, Faculty of Medicine Research Week 2015, Faculty of Medicine, University of Malaya (University) (11 May 2015 - 15 May 2015)
  18. PBL Case Design , PBL Training Workshop, College of Health Sciences, UMMC, UM (University) (15 Dec 2014 - 18 Dec 2014)
  19. Antivenom: Production, kinetics and dynamics, International Workshop on Advanced Marine animals & Snake Envenomation Management (AMSEM)2014, Malaysian Society on Toxinology (International) (02 Sep 2014 - 03 Sep 2014)
  20. Use of Laboratory Animals in Toxinological Studies, LASAM Scientific Seminar & AGM 2014, Laboratory Animal Science Association of Malaysia (National) (18 Aug 2014 - 18 Aug 2014)
  21. Antivenom and poisoning, UMMC Pharmacy Summit 2014, MSD and UMMC (University) (16 Aug 2014 - 16 Aug 2014)
  22. The use of laboratory animals in toxinological characterizations of snake venoms, Japanese Conference for Laboratory Animal Science and Technology, Japanese Association of Laboratory Animal Science (International) (15 May 2014 - 17 May 2014)
  23. Pharmacology of antivenom, Short Seminar Series on "Essential Introduction to Snakes, Venom and Envenomation", Malaysian Society on Toxinology (National) (19 Mar 2014 - 19 Mar 2014)
  24. Snake venom toxins: Toxinological research and application, Research lecture series for Master in Biotechnology (University) (03 Mar 2014 - 03 Mar 2014)
  25. Antivenom and Envenomation Management, 2nd International Workshop on Advanced Management of Marine Animals & Snake Envenomation Management., AMSEM (International) (04 Jun 2013 - 05 Jun 2013)
  26. PBL Trigger Writing, PBL Training Workshop for Tutors , Medical Education Research and Development Unit, Faculty of Medicine, UM (University) (26 Nov 2012 - 03 Dec 2012)
  27. Snake antivenom: the fundamental facts and optimization. Abstract book p. 14., 1st National Workshop on Advanced Management of Marine Animals & Snake Envenomation in Malaysia. Abstract book p. 14. Kuala Lumpur, Malaysia.  (International) (29 May 2012 - 30 May 2012)
  28. Snake venom composition and effects: a Malaysian context. Abstract book p. 13., 1st National Workshop on Advanced Management of Marine Animals & Snake Envenomation (International) (29 May 2012 - 30 May 2012)
  29. The toxinological properties of Merrem's humped-nose pit viper (Hypnale hypnale) and its neutralization by commercial antivenoms, 1st National Conference on Animal, Microbial, Plant Toxins & Snakebite Management 'Biotoxins in Health Disease', Indian Institute of Chemical Biology & KPC Medical College & Hospital (International) (11 Dec 2010 - 12 Dec 2010)
  30. PBL Trigger Writing, Problem-Based Learning Training Workshop 2010. Faculty of Medicine, University of Malaya, Kuala Lumpur. (6 & 11 October, 2010), Medical Education Research and Development Unit, Faculty of Medicine, UM (University) (06 Oct 2010 - 11 Oct 2010)
  31. Case Design for PBL , Problem Based Learning Workshop 2010 (for training in-campus tutors from all disciplines), Faculty of Medicine and Health Sciences jointly with CALM, University of Malaysia Sarawak, Kuching. (University) (21 Jul 2010 - 23 Sep 2013)
  32. Gain the Most from PBL!, Problem Based Learning Workshop 2010 (for training medical students and tutors from all disciplines), Faculty of Medicine and Health Sciences jointly with CALM, University of Malaysia Sarawak (University) (21 Jul 2010 - 23 Jul 2010)
EVENT ORGANISER
  1. -, Seminar and Workshop on Neuromuscular Pharmacology & Nerve-Muscle Preparation, Department of Pharmacology, and the Venom and Toxin Research Laboratory (University) (02 Nov 2016 - 04 Nov 2016)
ORAL PRESENTER
  1. Venomics of the Malayan Pit Viper, Calloselasma rhodostoma: Unravelling A Complex Toxin Arsenal through A Multi-Step Decomplexation Approach, Malaysian Society for Biochemistry and Molecular Biology Taylor s University Virtual Focused Meeting , Malaysian Society for Biochemistry and Molecular Biology and Taylor s University  (National) (19 Nov 2020 - 19 Nov 2020)
  2. Exploring the efficacy and limitation of antivenom neutralization against key neurotoxins of Afro-Asian cobras (Naja sp.), 19th World ocngress of Toxinology, Univesity of Haina and International Society on Toxinology (International) (24 Oct 2017 - 31 Oct 2017)
  3. Unveiling the venom proteome of Malaysian mangrove pit viper (Cryptelytrops purpureomaculatus): Insights into the biochemistry and neutralization profile of the venom, 21st Biological Sciences Graduate Congress, University of Malaya (International) (15 Dec 2016 - 17 Dec 2016)
  4. The plastic cobras: omics investigation of venom evolveability and allopatric variation, 8th World Congress of Herpetology, Nanjing Normal University, Hangzhou Normal University, Lishui University (International) (15 Aug 2016 - 21 Aug 2016)
  5. Snake venom study from the Indonesian perspective: On the Assessment of SABU (Serum Anti Bisa Ular), 1st Symposium on South East Asia Herpetology and Envenomation (SEASHE) in conjunction with The 4th Congress of Herpetological Society of Indonesia, Malang, 28th-29th August 2015, Universitas Brawijaya and Herpetological Society of Indonesia (International) (28 Aug 2015 - 29 Aug 2015)
  6. Venom gland transcriptome and venom proteome of Malaysian king cobra (Ophiophagus hannah), 10th Asia Pacific Conference on Animal, Plant and Microbial Toxins (IST-APC 2014), International Society on Toxinology (International) (14 Jun 2014 - 18 Jun 2014)
  7. Toxinological Characterizations of the venom of hump-nosed pit viper (Hypnale hypnale). , Three-Minute Thesis Contest (Ph.D). Faculty of Medicine, University of Malaya, Kuala Lumpur. (22 November, 2012), University of Malaya (University) (22 Nov 2012 - 22 Nov 2012)
  8. Profiling the venom of hump-nosed pit viper (Hypnale hypnale): Toward an optimization for treatment, diagnostics, monitoring and potential drug discovery. , Post-graduate Research Day (in conjunction with 19th Scientific Meeting of MSMBB 2012). University of Malaya, Kuala Lumpur. (31 October, 2012)., MSMBB (National) (31 Oct 2012 - 31 Oct 2012)
  9. ELISA in Hypnale hypnale Pit Viper Envenoming: An approach for diagnostic and therapeutic optimization. Programme and Proceedings, p. 36., 4th Regional Conference on Molecular Medicine.  (International) (09 Oct 2011 - 11 Oct 2011)
  10. Immune response elicited by immunization of rabbits with Hypnale hypnale venom and the ELISA cross-reactivities of the antibodies. Oral A3, p.82 , Proceedings of the 4th International Conference on Natural Toxins, Egyptian Society on Toxinology (International) (20 Dec 2010 - 22 Dec 2010)
  11. PBL: So far so good? Let s hear what student say about it., 1st Asia-Pacific Joint PBL Conference , Fu Jen Catholic University jointly with Taiwan Association of Medical Education (International) (22 Oct 2010 - 25 Oct 2010)
  12. How well can we bridge the gap between Pharmacology lectures and bedside prescribing? , The Association for Medical Education in Europe Conference (AMEE 2010), Glasgow, UK. (04-08 September, 2010), The Association for Medical Education in Europe (International) (04 Sep 2010 - 08 Sep 2010)
  13. Biochemical and toxinological characterisation of Hypnale hypnale pit viper venom and its neutralisation by a commercial antivenom. Oral 8, pp.36., 35th Annual Conference of the Malaysian Society for Biochemistry and Molecular Biology, MSBMB & CARIF (International) (27 Jul 2010 - 28 Jul 2010)
  14. Enzymatic and pharmacological activities of Merrem s humped-nose pit viper (Hypnale hypnale) venom and its neutralization by a commercial antivenom. O119, pp.64. , 24th Scientific Meeting of the Malaysian Society of Pharmacology and Physiology, MSPP (International) (02 Jun 2010 - 03 Jun 2010)
  15. Filling the Gap: From pharmacology lectures to bedside prescribing. OC-17, p. 32., 7th International Medical Education Conference , International Medical University (International) (24 Mar 2010 - 26 Mar 2010)
POSTER PRESENTER
  1. A closer look at the functional diversity of cytotoxins from Southeast Asian cobras: Biomedical and clinical significance, 1st International Electronic Conference on Toxins, MDIP Toxins (International) (16 Jan 2021 - 31 Jan 2021)
  2. Immunoreactivity and Neutralization Efficacy of Green Pit Viper Antivenom Against Hetero-Specific Pit Viper Venoms, Malaysian Society for Biochemistry and Molecular Biology Taylor s University Virtual Focused Meeting 2020, Malaysian Society for Biochemistry and Molecular Biology Taylor s University (National) (19 Nov 2020 - 19 Nov 2020)
  3. Toward improved antivenom management of snakebite envenomation in Southeast Asia: The Indonesian perspective, 19th World Congress of International Society on Toxinology , International Society on Toxinology (International) (08 Sep 2019 - 13 Sep 2019)
  4. Venomics of the Sri Lankan common krait (Bungarus caeruleus) and antivenom neutralization of the venom toxicity, 21st Biological Sciences Gradaute Congress, University of Malaya (International) (15 Dec 2016 - 17 Dec 2016)
  5. Venomics of Hydrophis schistosus, the beaked sea snake: a simple toxin arsenal cross-neutralised by two heterologous antivenoms, The 18th IST World Congress on Toxinology, International Society on Toxinology (International) (25 Sep 2015 - 30 Sep 2015)
  6. Geographical variations of Naja kaouthia (monocled cobra) venom from Southeast Asia: a venomic and functional study, The 18th World congress on Toxinology, International Socienty on Toxinology (International) (25 Sep 2015 - 30 Nov 2015)
  7. Naja sputatrix and Naja sumatrana: two phylogenetically related spitting cobras with distinct venom composition and neutralization profiles, 1st Symposium on South East Asia Herpetology and Envenomation (SEASHE) in conjunction with The 4th Congress of Herpetological Society of Indonesia, Universitas Brawijaya and herpetological Society of Indonesia (International) (28 Aug 2015 - 29 Aug 2015)
  8. Geographical variations of monocled cobra (Naja kaouthia) venoms: impacts on the venom toxicity and antivenom neutralization, Faculty of Medicine Research Week 2015 (University) (11 May 2015 - 15 May 2015)
  9. Expired and Room Temperature-stored Antivenoms: Are they still effective?, Faculty of Medicine Research Week 2015 (11 May 2015 - 15 May 2015)
  10. Evaluating the purity and activities of a log-expired Taiwan bivalent antivenom, Faculty of Medicine Research Week 2015 (University) (11 May 2015 - 15 May 2015)
  11. Venom proteome of Calloselasma rhodostoma (malayan pit viper) unmasked by liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS) following different tryptic digestion methods., Malaysian Society of Biochemistry and Molecular Biology Annual Conference, Malaysian Society of Biochemistry and Molecular Biology, (International) (25 Jun 2014 - 26 Jun 2014)
  12. Proteomic studies of venoms of Naja kaouthia (monocellate cobra) from Malaysia and Thailand, 38th Malaysian Society of Biochemistry and Molecular Biology (MSBMB) Conference, MSBMB (National) (28 Aug 2013 - 29 Aug 2013)
  13. Preventing the Development of Acute Kidney Injury from Hump-nosed Pit Viper (Hypnale hypnale) Bites in Mice with a Paraspecific Antivenom. Poster 322. Pp.81-82., 17th World Congress of the International Society on Toxinology Animal, Plant and Microbial Toxins & Venom Week 2012; 4th International Scientific Symposium on All Things Venomous, International Society on Toxinology (International) (08 Jul 2012 - 13 Jul 2012)
  14. Toxicological and immunological characterization of the Sri Lanka hump-nosed pit viper (Hypnale hypnale) venom. Program & Abstracts Book, Poster: 61, p. 153. Valencia, Spain. , 17th Congress of the European Section of the INTERNATIONAL SOCIETY on TOXINOLOGY (International) (11 Sep 2011 - 15 Sep 2011)
  15. Interprofessional learning on prescribing skills - Do the undergraduates support this? P-11, 6th Pharmacy Education Symposium, Monash University (International) (11 Jul 2011 - 13 Jul 2011)
  16. Pharmacokinetics of the venom of hump-nosed pit viper (Hypnale hypnale) in rabbits. In Journal of Pharmacological Sciences, 115(1), pp.235P. P2J23-3, Proceedings of the 84th Annual Meeting of the Japanese Pharmacological Society and the 11th Southeast Asian Western Pacific Regional Meeting of Pharmacologists (International) (22 Mar 2011 - 24 Mar 2011)
  17. Prescribing Skills Training: A mean of integrating hardcore knowledge, enhancing clinical competency and strengthening soft skills of medical undergraduates, 8th Asia-Pacific Medical Education Conference, National University of Singapore (International) (28 Jan 2011 - 30 Jan 2011)
  18. Pathway Analysis of differently expressed genes in heart of rat injected with lethal dose of naja sputatrix (Malayan cobra) snake venom., 18th Scientific Meeting of the Malaysian Society for Molecular Biology and Biotechnology (International) (18 Aug 2009 - 20 Aug 2009)
PRESENTER
  1. Learning pharmacokinetics through a personalised learning approach, Learning Improvement and Teaching Enhancement Conference (LITEC) 2020, The Academic Enhancement and Leadership Development Centre (ADeC) (National) (25 Aug 2020 - 27 Aug 2020)
  2. Comparative Venom-gland transcriptomics of Monocled Cobra (Naja kaouthia) from Malaysia and Thailand: On Evolvability and Geographical Variation of Venom, 12th congress of the Pan-American Section of the International Society on Tooxinolgy, International Society on Toxinology (International) (18 Sep 2016 - 23 Sep 2016)
OTHERS
  1. Pre-symposium workshop: Venomics in Toxinology, The 4th International Symposium on ASEAN Marine Animals & Snake Envenoming (Poisoning) Management AMSEM 2016, Malaysian Society on Toxinology (International) (28 Nov 2016 - 01 Dec 2016)
  2. A beautiful, endemic hemotoxic high-land pit viper, Faculty of Medicine Research Week 2015 (University) (11 May 2015 - 15 May 2015)

ACADEMIC/PROF. SERVICES


Evaluation
  1. (2024) Pakar Panel of Expert (Poe) Fih Npra, National, (Reviewer)
  2. (2023) External Examiner, Phd Thesis, National, (Reviewer)
  3. (2023) External Examiner, Phd Thesis, National, (External Examiner)
  4. (2021) Review of abstracts submitted to YSN-ASM International Scientific Virtual Conference (ISVC) 2021 , (Reviewer)
  5. (2021) Guest Editor, Frontiers in Immunology , (Editor)
  6. (2021) Editor, Collection for Frontiers in Pharmacology, (Editor)
  7. (2020) Reviewed article for journal Toxins Review, (Reviewer)
  8. (2020) Assessor for science communication assignment (postgraduate), (Reviewer)
  9. (2020) Reviewing article for open-access journal: Frontiers in Immunology, (Reviewer)
  10. (2020) Review article for open-access journal: Frontiers in Pharmacology, (Reviewer)
  11. (2020) Reviewed article for Journal of Venomous Animals and Toxins including Tropical Diseases, (Reviewer)
  12. (2020) Reviewing article for journal Drug Discovery Today, (Reviewer)
  13. (2020) Reviewing article for Journal of Venom Research, (Reviewer)
  14. (2020) Reviewing article for journal Chemophere, (Reviewer)
  15. (2020) Reviewed article for journal Toxicology and Applied Pharmacology, (Reviewer)
  16. (2020) Reviewing article for open-access journal: PLoS Neglected Tropical Diseases, (Reviewer)
  17. (2020) Reviewing article for open-access journal Frontiers in Bioengineering and Biotechnology, (Reviewer)
  18. (2020) Reviewing article for journal Analytical Chimica Acta, (Reviewer)
  19. (2020) Reviewed article for journal Bioactive Materials, (Reviewer)
  20. (2020) Evaluation for Communication Skills in Research Methodology Course (MMedSc), (Internal Examiner)
  21. (2019) Invited Assessor for International Grant (2019): UKRI Future Leaders Fellowships for applicant, (Reviewer)
  22. (2019) Reviewing articles for journal Comparative Biochemistry and Physiology , (Reviewer)
  23. (2016) Reviewed articles for journal Toxicon, (Reviewer)
  24. (2016) Reviewed article for Journal of Proteomics, (Reviewer)
  25. (2015) Reviewed manuscript (full article) submitted to J Proteomics , (Reviewer)
  26. (2015) Reviewed manuscript (full article 2) submitted to Toxicon (2015) , (Reviewer)
  27. (2015) Reviewed manuscript (full article) submitted to Journal of Toxins , (Reviewer)
  28. (2015) Reviewed manuscript (full article) submitted to Toxicon, (Reviewer)
  29. (2015) Reviewed manuscript (full article) submitted to Journal of Proteomics, (Reviewer)
  30. (2015) Reviewed manuscript (revised full article) submitted to Journal of Toxins, (Reviewer)
  31. (2015) Reviewed manuscript (full revised article) submitted to Journal of Journal of Neurology, Neurosurgery and Psychiatry, (Reviewer)
  32. (2015) Reviewed manuscript (full article) submitted to PLoS Neglected Tropical Diseases, (Reviewer)
  33. (2015) Reviewed poster abstracts(17) For FOM Research Week 2015, (Reviewer)
  34. (2015) Reviewed manuscript (full article) submitted to Journal of Neurosciences in Rural practice, (Reviewer)
  35. (2015) Internal examiner for M.Med.Sc. Thesis/ Puvaneswari a/p Meganathan , (Internal Examiner)
  36. (2015) Internal examiner for M.Med.Sc Thesis / Tan Peow Teik , (Internal Examiner)
  37. (2015) Judge for the Final Round Poster Presentation for FOM Research Week 2015 , (Panelist)
  38. (2014) Asia pacific Journal of Molecular Biology and Biotechnology, (Reviewer)
  39. (2014) PhD for HONG WEI-HAN (MHA 120051), (Internal Examiner)
  40. (2014) Mesyuarat Semakan Semula "Clinical Protocol Management of Snake Bite", (Reviewer)
  41. (2014) Tropical Medicine and Surgery , (Reviewer)
  42. (2014) Bites, snakes (Chapter 91), (Reviewer)
  43. (2014) M.Med.Sc. dissertation, (Internal Examiner)
  44. (2013) Journal of Biomedical Research , (Reviewer)
  45. (2013) M.Med.Sc. candidature defense for Kamelia Saremi , (Internal Examiner)
  46. (2013) PLoS Neglected Tropical Diseases, (Reviewer)
  47. (2013) M.Med.Sc. candidature defense for Puvaneswari Meganathan , (Internal Examiner)
  48. (2013) Monograph on Snake Bite by the Malaysian Toxicology Services , (Commentor)
  49. (2013) Topic 101: Snake Bite, Paediatric Protocol for Malaysia (3rd edition), Ministry of Health, Malaysia. (2013) , (Reviewer)
Contribution to external organisation
  1. (2024) Panel of Experts for First-in-Human Trials., National, (Resource Person)
  2. (2024) Panel of Expert (Poe) for First-in-Human (Fih) Clinical Studies, National, (Expert Advisor)
  3. (2021) Guest editor, Frontiers in Immunology, Frontiers in Immunology
  4. (2021) Editor, special collection in Frontiers in Pharmacology, Frontiers in Pharmacology
  5. (2019) Asia Pacific Association of Medical Toxicology 2019 Pre-conference workshop, Asia Pacific Association of Medical Toxicology
  6. (2019) Editor for MST Newsletter, Malaysian Society on Toxinology
  7. (2019) Malaysian Society of Pharmacology and Physiology 33rd Conference, 2019, MSPP
  8. (2016) Japanese Medical Innovation Programme, Kyushu University, International
  9. (2015) Chairing Wednesday Clinical Symposium on 8/7/2015 (Speaker: Prof Gopalakrishnakone P. from NUS), Faculty of Medicine, University of Malaya
  10. (2015) Committee member (Scientific) for FOM Research Week 2015, 11-15 May 2015, Faculty of Medicine, University of Malaya
  11. (2015) Committee member for Golden Helix Symposia 2015, 11-13 March 2015, University of Malaya and Golden helix Foundation
  12. (2015) Committee member and Emcee for Snakebite Envenoming Management Workshop in Kuala Lumpur 2015, Malaysian Society on Toxinology (MST) & JKWP KL/Putrajaya @ Auditorium, Hospital Rehabilitasi, Kuala Lumpur
  13. (2015) Modulator for Forum on "Steps and bumps on the road to becoming a researchers", 15th May 2015, FOM Research Week 2015 , Faculty of Medicine, University of Malaya
  14. (2014) Interview with selected FOM alumni in conjunction with the Faculty 50th Anniversary, Faculty of Medicine
  15. (2014) International Symposium on Advanced Marine animals & Snake Envenomation Management(AMSEM)2014, Malaysian Society on Toxinology
  16. (2014) Health screening for subjects in Bioequivalence Study, University of Malaya Bioequivalence and Testing Centre
  17. (2014) Contribution of article and information to Petri Dish, Reseach Magazine, Aug 2014, Petri Dish

SUPERVISION


Postgraduate Student
PhD/ Doctoral
  1. (2020) PROTEOMICS AND IMMUNOREACTIVITY STUDY OF THE MALAYAN PIT VIPER (CALLOSELASMA RHODOSTOMA) VENOM, ESTHER TANG LAI HAR
  2. (2014) PROTEOMICS AND IMMUNOREACTIVITY STUDY OF THE MALAYAN PIT VIPER (CALLOSELASMA RHODOSTOMA) VENOM, Esther Tang Li Har
  3. (2013) Toxinology and Biocehmistry of Medically Important Snake Venoms in the Region, Tan Kae Yi
Master
  1. (2017) Proteomic and Toxinological Characterization of Banded Krait (Bungarus fasciatus) Venom, Hia Yi Lin
Under Graduate Students
  1. (2022) Developing a lateral flow immunoassay-based snakebite diagnostic tool.
  2. (2022) Characterization of African cobra venoms.
  3. (2019) Immunological Characterization of Three-Finger Toxin Isolated from Thai Monocled Cobra (Naja kaouthia) Venoms
  4. (2019) Immunological Characterization of Long Neurotoxins from Snake Venoms
  5. (2018) Toxinological Characterization of Long Neurotoxin from Snake Venom
  6. (2018) Profiling of Unknown Novel Proteins in Pit Viper Venom
  7. (2018) Evaluation of the immunoreactivity and neutralization efficacy of two polyvalent antivenoms against selected African viperids venom
  8. (2018) Biochemical and Immunological Studies of King Cobra (Ophiophagus hannah) venoms
  9. (2017) Protein Profiling and Immunoreactivity of the Venoms of Pit Viper Species from China and Taiwan
  10. (2017) Protein Composition Analysis of Pit Viper Venoms
  11. (2017) Profiling of Cobra Venoms from Different Geographical Regions
  12. (2017) Immunoreactivity and Lethality Neutralization of Two Polyvalent Antivenoms Against Selected African Elapid Venoms
  13. (2017) Functional Characterization of Chinese and Taiwanese Pit Viper Venoms
  14. (2017) Comparative Proteomic Analysis and Immunoreactivity of Snake Venoms
  15. (2016) Biomedical study of the venoms of two Southeast Asian green pit vipers
  16. (2016) Biomedical Study of the Venoms of Trimeresurus spp. of Pit Vipers
  17. (2015) Biomedical Studies on The Composition and Immunological Reactivity of a Long-Expired Taiwan Bivalent Antivenom
  18. (2015) Biomedical studies on composition and immunological reactivity of expired Neuro Polyvalent antivenom
  19. (2014) Effects of expiry and room-temperature treatment on Hemato Polyvalent Antivenom (HPAV): A physicochemical, immunological and functional characterization.
  20. (2014) A Multifaceted Study for the Preclinical Assessment of a Long Expired Antivenom
  21. (2013) Elective project: Toxinological Characterisations of Snake Venoms
  22. (2012) Non-medical elective project (snakes and venoms)

TEACHING


Master
  1. (2023) BMS - Basic Medical Sciences for Clinical Masters
  2. (2019) BMS - Postgraduate Basic/Clinical Medical Sciences
  3. (2017) BMS - Postgraduate Basic/Clinical Medical Sciences
  4. (2016) BMS - Postgraduate Basic/Clinical Medical Sciences
Bachelor
  1. (2023) MIC3010 - Advances in Medical Pharmacology
  2. (2023) MIX3003 - Drugs: from Target to Market
  3. (2023) DIA2006 - Pharmacology
  4. (2023) MIA 2001 - Universiti Malaya Medical Programme (Ummp)
  5. (2022) MIC3010 - Advances in Medical Pharmacology
  6. (2022) MIX3003 - Drugs: from Target to Market
  7. (2022) DIA2006 - Pharmacology
  8. (2022) MIC2004 - Principles in Pharmacology and Toxicology
  9. (2022) MIA 2001 - Universiti Malaya Medical Programme (Ummp)
  10. (2020) UMMP - University of Malaya Medical Programme
  11. (2019) DIA2006 - Pharmacology
  12. (2019) MIA2001 - University of Malaya Medical Programme
  13. (2019) MIC2004 - Principles in Pharmacology and Toxicology
  14. (2019) MIC3010 - Advances in Medical Pharmacology
  15. (2019) MID1009 - Pharmacology in Nursing
  16. (2018) DIA2006 - Pharmacology
  17. (2018) MIA1001 - University of Malaya Medical Programme
  18. (2018) MIA2001 - University of Malaya Medical Programme
  19. (2018) MIC2004 - Principles in Pharmacology and Toxicology
  20. (2018) MID1009 - Pharmacology in Nursing

SOCIAL RESPONSIBILITY ACTIVITIES


  • A Talk On “Toxinology of Snake Venom” – Webinar “Snakes and Snakebites in Pets”, Forest Research Institute Malaysia, Scheduled 21/03/2021., (21 Mar 2021 - 21 Mar 2021)
  • Newspapers Interview by Nanyang Daily: Snake Venom and Antivenom Research, Published 03/02/2021., (03 Feb 2021 - 03 Feb 2021)
  • "Lurking Snakes On The Run" Awareness Talk At Kl Science Cafe (Virtual): 15th August 2020., (15 Aug 2020 - 15 Aug 2020)
  • "Two Faces of Snake Venoms: to Kill and to Heal" Science Talks At Pusat Sains Negara, in Conjunction With Minggu Sains Negara 2019, (06 Apr 2019 - 06 Apr 2019)
  • "On Move With Climate Change: Who Let The Snakes Out?" Science Talks At Pusat Sains Negara, in Conjunction With Minggu Sains Negara 2019, (06 Apr 2019 - 06 Apr 2019)
  • "Exploring The Amazing Snake Venoms" Educational Talk At Petrosains, Klcc 28th March 2019, (28 Mar 2019 - 28 Mar 2019)
  • Chief Editor for The Newsletter of Malaysian Society On Toxinology (Mst), (01 Feb 2019 - 31 Dec 2021)
  • First Aid On Snakebite @ World First Aid Day 2018, Canselor Tuanku Muhriz Medical Center (Ukmmc), (17 Nov 2018 - 17 Nov 2018)
  • Science Cafe Kl: Outreach Activities - Talk and Exhibition On Snakebite Management and Research @The Bee, Publika, Kl., (10 Oct 2018 - 10 Oct 2018)
  • Educational Booth Science Outreach Activities, 7th Asean+3 Junior Science Odyssey (29/7-4/8), (29 Jul 2018 - 04 Aug 2018)
  • Newspaper Interview: On Snakebite Envenomation, Research and Myths, by Sin Chew Daily 2018, (24 Jul 2018 - 24 Jul 2018)
  • Committee for National Science Challenge (State Level) 2018, (11 Jun 2018 - 08 Jul 2018)
  • Science Talk @Umbi Research Update Series: Snake Venoms: -Omics & Pharmacology., (25 May 2018 - 25 May 2018)
  • Educational Booth Science Outreach Activities for Public, Stem Carnival (Minggu Sains Negara Selangor) 2018, (06 Apr 2018 - 08 Apr 2018)
  • Public Science Communication: Snake Venom and Antivenom, @Famelab Central Heat and Finale 31/3/2018 & 3/5/2018, (31 Mar 2018 - 03 May 2018)
  • Chief Editor for The Malaysian Society On Toxinology Newsletter Series 2018, (01 Jan 2018 - 31 Dec 2018)
  • Knowledge and Awareness Promotion: Venoms and Toxins for Public, Managed by WWW.Vetoxlab.Com, (01 Jan 2017 - 31 Dec 2021)
  • Contributed as Author for Asian Research News Published On 6th Sep 2016 "The Blue Coral Snake, Calliophis Bivirgata: a Mysterious Beauty Armed With Exotic Toxins", (06 Sep 2016 - 06 Sep 2016)
  • Contributed as Author for Umr Bulletin: it Matters Where The Cobra Comes from: Naja Kaouthia, One Species With Variable Venom", (02 Sep 2016 - 02 Sep 2016)
  • Contributed as Author in Scientific Malaysian Magazine, Issue 12, Page 32-38 On Antivenoms: Science, Values and Challenges, (12 Jun 2016 - 12 Jun 2016)
  • Newspaper Interview � Snakebites, Venoms and Antivenoms: The Malaysian Context. Guang Ming Daily (Pnc11 C1). (13th February, 2013), (13 Feb 2013 - 13 Feb 2013)