Curriculum Vitae

DR. HONG SOK LAI

Research Officer
  • Institute of Research Management and Services

AREAS OF EXPERTISE

  • CHARACTERIZATION OF MOLECULES
  • NATURAL PRODUCTS CHEMISTRY

ACADEMIC QUALIFICATION

  • PhD(UM)(2011), (Biotechnology)
    Universiti Malaya (UM)
  • MSc(Chemistry)(UKM), (Organic and Natural Products Chemistry)
    Universiti Kebangsaan Malaysia (UKM)
  • BSc(Hons)(Chemistry)(UPM), (Sains)
    Universiti Putra Malaysia (UPM)

ADMINISTRATIVE DUTIES

  • Quality Manager
    02 Mar 2017 - 31 Oct 2018 (University Malaya)
  • Ahli Jawatankuasa Pembelian Peralatan Makmal Secara Berpusat Universiti Malaya
    27 Apr 2017 - 31 Oct 2018 (University Malaya)

AWARD AND STEWARDSHIP

  • Best Poster Award for "Cytotoxic Investigations on Zingiber Officinale Variants Jahe Emprit and Jahe Gajah"
    USM, PENANG, 2008 (International)

PUBLICATIONS

Article in Journal
WoS
  1. Tay, K. C., Tan, L. T. H., Chan, C. K., Hong, S. L., Chan, K. G., Yap, W. H., . . . Goh, B. H. (2019). Formononetin: A Review of Its Anticancer Potentials and Mechanisms. Frontiers in Pharmacology, 10, 19. doi:10.3389/fphar.2019.00820
  2. Seow, S. L. S., Hong, S. L., Lee, G. S., Abd Malek, S. N., Sabaratnam, V. (2017). 6-shogaol, a neuroactive compound of ginger (jahe gajah) induced neuritogenic activity via NGF responsive pathways in PC-12 cells. Bmc Complementary and Alternative Medicine, 17, 11.
  3. Hong, G. W., Hong, S. L., Lee, G. S., Yaacob, H., Abd Malek, S. N. (2016). Non-aqueous extracts of Curcuma mangga rhizomes induced cell death in human colorectal adenocarcinoma cell line (HT29) via induction of apoptosis and cell cycle arrest at G(0)/G(1) phase, Asian Pacific Journal of Tropical Medicine. 9(18-15), Article
  4. Hong, S. L., Lee, G. S., Rahman, S., Hamdi, O. A. A., Awang, K., Nugroho, N. A., Abd Malek, S. N. (2014). Essential Oil Content of the Rhizome of Curcuma purpurascens Bl. (Temu Tis) and Its Antiproliferative Effect on Selected Human Carcinoma Cell Lines, Scientific World Journal. (7), Article
  5. Phan, C. W., Lee, G. S., Hong, S. L., Wong, Y. T., Brkljaca, R., Urban, S., Abd Malek, S. N., Sabaratnam, V. (2014). Hericium erinaceus (Bull.: Fr) Pers. cultivated under tropical conditions: isolation of hericenones and demonstration of NGF-mediated neurite outgrowth in PC12 cells via MEK/ERK and PI3K-Akt signaling pathways, Food Function. 5(12), 3160-3169
Scopus
  1. Chew S.K., Teoh W.H., Hong S.L., Yusoff R. (2023). Rutin extraction from female Carica papaya Linn. using ultrasound and microwave-assisted extractive methods: Optimization and extraction efficiencies, Heliyon. 9(10). doi:10.1016/j.heliyon.2023.e20260
  2. Philip, K., Malek, S. N. A., Sani, W., Shin, S. K., Kumar, S., Lai, H. S., et al. (2009). Antimicrobial activity of some medicinal plants from Malaysia, American Journal of Applied Sciences. 6(8), 1613-1617
  3. Malek, S. N. A., Wahab, N. A., Yaacob, H., Shin, S. K., Lai, H. S., Serm, L. G., et al. (2008). Cytotoxic activity of Pereskia bleo (Cactaceae) against selected human cell lines, International Journal of Cancer Research. 4(1), 20-27
Others
  1. Tong Ling Tan, Kian Mun Lee, Chin Wei Lai, Sok Lai Hong, Suraya Abdul Rashid, Photocatalytic degradation mechanisms of dimethyl phthalate esters by MWCNTs-anatase TiO2 nanocomposites using the UHPLC/ORBITRAP/MS technique, Advanced Powder Technology, 31, pp. 533 - 547, (2020)
  2. Tan TL, Lai CW, Hong SL, Rashid SA. (2018). New insights into the photocatalytic endocrine disruptors dimethyl phathalate esters degradation by UV/MWCNTs-TiO2 nanocomposites, Journal of Photochemistry and Photobiology, A: Chemistry, 364(1): 177-189. https://doi.org/10.1016/j.jphotochem.2018.05.019
  3. Suhaimi SA, Hong SL, Abdul Malek SN. (2017). Rutamarin, an active constituent from Ruta angustifolia Pers., induced apoptotic cell death in the HT29 colon adenocarcinoma cell line. Phcog Mag, 13 (50), 179-88
  4. Abdullah, F., Subramanian, P., Ibrahim, H., Malek, S. N. A., Lee, G. S., Hong, S. L. (2015). Chemical Composition and Antifeedant Activity of the Rhizomes of Alpinia galanga against Asian Subterranean Termites, Coptotermes gestroi and Coptotermes curvignathus. Journal of Insect Science. Accepted.
  5. Feroz, S. R., Teoh, Y. J., Mohamad, S. B., Hong, S. L., Malek, S. N. A., & Tayyab, S. (2015). Interaction of flavokawain B with lysozyme: A photophysical and molecular simulation study. Journal of Luminescence.
  6. Hong Sok Lai, Syntyche Seow Ling Sing, Vikineswary Sabaratnam, Lee Guan Serm, Sri Nurestri Abd Malek. 6-Shogaol, a potential neuritogenic compound that mimics the neurite outgrowth activity of nerve growth factor. In: Supayang Voravuthikunchai and Peter Howe. Report on the Fifth International Conference on Natural Products for Health and Beauty (NATPRO 5) held in Thailand, 6-8th May, 2014. 2014. Nurients. 6: 4144.
  7. Lee Guan Serm, Hong Sok Lai, Hong Gin Wah, Nurfina Aznam, Hashim Yaacob, Mahmood Ameen Abdulla Hassan, Norhaniza Aminudin, Sri Nurestri Abd Malek. Anti-proliferation and acute toxicity studies of Curcuma mangga rhizomes. In: Supayang Voravuthikunchai and Peter Howe. Report on the Fifth International Conference on Natural Products for Health and Beauty (NATPRO 5) held in Thailand, 6-8th May, 2014. 2014. Nutrients. 6: 4127-4128.
  8. Sri Nurestri A. Malek, Guan Serm Lee, Sok Lai Hong, Hashim Yaacob, Norhanom Abdul Wahab , Jean-Frederic Faizal Weber and Syed Adnan Ali Shah. (2011). Phytochemical and Cytotoxic Investigations of Curcuma mangga Rhizomes. Molecules. 16(6): 4539-4548.
  9. Sri Nurestri Abd. Malek, Halijah Ibrahim, Hong Sok Lai, Nor Azah Mohamad Ali, Lee Guan Serm and Chan Kam Seng. 2005. The Essential Oils of Zingiber officinale Variants. Malaysian Journal of Science. 24(2): 37-43.
  10. Sri Nurestri Abd. Malek, Halijah Ibrahim, Hong Sok Lai, Nor Azah Mohamad Ali, Lee Guan Serm, Chan Kam Seng and Masitah Mohd. Yusoff. 2005. Essential Oils of Zingiber ottensii Valet and Zingiber zerumbet (L.) from Sabah. Malaysian Journal of Science. 24(1): 49-58.
  11. Sri Nurestri Abd. Malek, Hong Sok Lai, Norhayati Muhammad, Noor Azah Mohamad Ali and Nigel Perry. 2005. Investigation on the Stem Bark of Trema orientalis. Malaysian Journal of Science.24(1): 113-119.

RESEARCH PROJECT

National
  1. 2009 - 2010, Postgraduate Research Grant(PPP)
    Cytotoxic and Apoptotic Activities of Pure Compounds (Isolated from Ethyl Acetate Extract of Jahe Gajah) Against Selected Cell Lines ( Co-Inventor)
  2. 2007 - 2007, Postgraduate Research Grant(PPP)
    Cytotoxic and apoptotic Activities of [6]-gingerol against selected cell lines ( Co-Inventor)
  3. 2005 - 2006, Short Term Research Fund (Vote F)(PJP)
    Bioactivity and Chemical Investigations on Zingiber officinale variants Jahe Emprit and Jahe Gajah ( Consultant)

PAPER PRESENTED

ORAL PRESENTER
  1. 6-Shogaol, a Potential Neuritogenic Compound That Mimics the Neurite Outgrowth Activity of Nerve Growth Factor, The 5th International Conference on Natural Products for Health and Beauty (NATPRO 5) (International) (06 May 2014 - 08 May 2014)
  2. Cytotoxic Principles from Zingiberaceae Species, International Conference on Natural Products 2010 (International) (10 Dec 2010 - 12 Dec 2010)
  3. Cytotoxic studies on three Curcuma species, 5th International Symposium on the Family Zingiberaceae (06 Jul 2009 - 09 Jul 2009)
  4. Cytotoxic Activities of Some Sesquiterpenoids from Selected Zingiberaceae Species, 5th Malaysian International Conference on Essential Oils, Fragrance and Flavour Materials (MICEOFF5) (28 Oct 2008 - 30 Oct 2008)
  5. Cytotoxic Studies of Some Zingiberacea Species , Twelfth Symposium on Medicinal Plants, Spices and Other Natural Products (ASOMPS XII), (13 Nov 2006 - 18 Nov 2006)
  6. Chemical Study on the Extract of the Stem Bark of Trema orientalis., 21th Annual Seminar of the Malaysian Natural Products Society, Faculty of Allied Health Sciences, UKM and Malaysian Natural Products Society (22 Nov 2005 - 23 Nov 2005)
  7. The Essential Oils of Four (4) Closely Related Variants of Zingiber Officinale., 4th Malaysian International Conference Essential Oils and Flavour and Fragrance Materials , Kerajaan Negeri Perlis, Kolej Universiti Kejuruteraan Utara Malaysia dan Institut Kimia Malaysia (08 May 2005 - 11 May 2005)
POSTER PRESENTER
  1. In vitro anti-cancer activities of some Zingiberaceae species against selected cancer cell lines., The 4th International Conference on Natural Products for Health and Beauty (NATPRO 4) , Chiang Mai, Thailand. (International) (28 Dec 2012 - 30 Dec 2012)
  2. Cytotoxic investigations on Curcuma inodora, Malaysian Natural Product International Seminar (MNPIS) 2009 Silver Jubilee (23 Nov 2009 - 24 Nov 2009)
  3. Cytotoxic investigations on Zingiber Officinale variant jahe gajah, Malaysian Natural Product International Seminar (MNPIS) 2009 Silver Jubilee (23 Nov 2009 - 24 Nov 2009)
  4. Antioxidant and cytotoxicity activities of Swietenia macrophyllia King, International Conference of Natural Products and Traditional Medicine, ICNPTM 2009, (16 Oct 2009 - 18 Oct 2009)
  5. Cytotoxic Activity of Curcuma aeruginosa (Temu hitam) and Curcuma zedoaria (Temu putih) against selected human cancer cell line, 13th Asian Symposium on Medicinal Plants, Spices and Other Natural Products (ASOMPS XIII) (03 Nov 2008 - 06 Nov 2008)
  6. Chemical Invetigation on Fresh Fruit Bodies of Pleurotus Sajor-Caju (Oyster Mushroom), 13th Asian Symposium on Medicinal Plants, Spices and Other Natural Products (ASOMPS XIII) (03 Nov 2008 - 06 Nov 2008)
  7. Cytotoxic Investigations on Zingiber Officinale Variant Jahe Gajah, 13th Asian Symposium on Medicinal Plants, Spices and Other Natural Products (ASOMPS XIII) (University) (03 Nov 2008 - 06 Nov 2008)
  8. Antimicrobial Activity of Eight Medicinal Plants from Malaysia, 2nd Penang International Conference for Young Chemists 2008., USM, Penang (18 Jun 2008 - 20 Jun 2008)
  9. Cytotoxic Investigations on Zingiber Officinale Variants Jahe Emprit and Jahe Gajah, 2nd Penang International Conference for Young Chemists 2008, USM (University) (18 Jun 2008 - 20 Jun 2008)
  10. Chemical Characterization of Zederone and 4-(4-hydroxyphenyl)butan-2-one., 12th Asian Chemical Congress (12 ACC) (23 Aug 2007 - 25 Nov 2007)
  11. Cytotoxic Activity of Pereskia corrugata Against Selected Cell Lines, Twelfth Symposium on Medicinal Plants, Spices and Other Natural Products (ASOMPS XII) (13 Nov 2006 - 23 Nov 2006)
  12. Essential Oils of Zingiber ottensii and Zingiber zerumbet from Sabah., 4th Malaysian International Conference Essential Oils and Flavour and Fragrance Materials, Kerajaan Negeri Perlis, Kolej Universiti Kejuruteraan Utara Malaysia dan Institut Kimia Malaysia (08 May 2005 - 11 May 2005)
  13. The Essential Oil of 5 Curcuma Species from Malaysia, 20th Annual Seminar of the Malaysian Natural Products Society, Malaysian Natural Products Society (29 Nov 2004 - 30 Nov 2004)
  14. Chemical Investigation of Two Curcuma Species from Malaysia., 20th Annual Seminar of the Malaysian Natural Products Society, Malaysian Natural Products Society (29 Nov 2004 - 30 Nov 2004)
  15. Investigation on the Stem Bark of Trema orientalis., 19th Annual Seminar & Workshop on the Malaysian Natural Products Society, University of Malaya (13 Oct 2002 - 16 Oct 2002)
OTHERS
  1. Anti-Proliferation and Acute Toxicity studies of Curcuma mangga rhizomes, The 5th International Conference on Natural Products for Health and Beauty (NATPRO 5) (International) (06 May 2014 - 08 May 2014)
  2. Potential anticancer agents from selected Zingiberaceae species, IUPAC 2013, 44th World Chemistry Congress (International) (11 Aug 2013 - 16 Aug 2013)

ACADEMIC/PROF. SERVICES

Evaluation
  1. (2013) Effect Of Solvents On The [6]-Gingerol Content Of Ginger Rhizome And Alligator Pepper Seed in International Research Journal of Pure and Applied Chemistry, (Reviewer)

COURSE ATTENDED

Internal / External Course
EXTERNAL COURSE
  1. BENGKEL ISO/IEC17025:2017 ? GENERAL REQUIREMENTS FOR THE COMPETENCE OF TESTING AND CALIBRATION LABORATORIES BAGI AKTIVITI PENDIDIKAN MENGENAI STANDARDISASI BERSAMA INSTITUSI PENGAJIAN TINGGI, Jabatan Standard Malaysia, Cyberjaya, Selangor (15 May 2018 - 16 May 2018)
  2. SPECIALIST COURSE: ROUTE TO IMPACT FOR RESEARCH MANAGERS, Monash University Malaysia, Sunway (10 Feb 2023 - 10 Feb 2023)
INTERNAL COURSE- ORGANIZED BY PTJ
  1. MALAYSIAN RESEARCH MANAGEMENT AND GOVERNANCE 2015 ? 2018 - RESEARCH IMPACT, Bilik Seminar 1 & 2, Kppi, Universiti Malaya (21 Mar 2018 - 21 Mar 2018)