Curriculum Vitae

DR. SITI AMALINA BINTI INCHE ZAINAL ABIDIN

Senior Lecturer
  • Department of Oral and Craniofacial Sciences
    Faculty of Dentistry
  • +603-79677408

AREAS OF EXPERTISE

  • PRIMARY CILIA
  • EXTRACELLULAR VESICLES (EVS)
  • EXTRACELLULAR MATRIX, CELL SIGNALLING, CANCER METABOLISM
  • FIBROBLAST, MICRORNAS, TUMOUR MICROENVIRONMENT
  • TRADITIONAL MEDICINE AND NATURAL PRODUCTS

ACADEMIC QUALIFICATION

  • PhD, (Dentistry)
    University of Sheffield, Sheffield, Uk
  • MSc(ChemPath), (Chemical Pathology)
    Univ. Sains Malaysia (Kubang Kerian)
  • BSc(BioMedSc)(Hons), (Biomedical Science)
    Universiti Putra Malaysia (UPM)

ADMINISTRATIVE DUTIES

  • Coordinator
    29 Jul 2022 - 28 Jul 2023 (Department)
  • Task Force Member
    24 May 2021 - 23 May 2023 (Faculty)
  • Coordinator
    01 Jan 2019 - 31 Dec 2022 (Faculty)
  • Committee Members
    15 Oct 2022 - 16 Oct 2022 (National)
  • Chairman
    18 Aug 2022 - 18 Aug 2022 (Department)
  • Chairman
    08 Jun 2022 - 08 Jun 2022 (Faculty)
  • Committee Members
    08 Nov 2021 - 23 Mar 2022 (Faculty)
  • Chairperson
    23 Dec 2020 - 23 Dec 2020 (Faculty)
  • PENEMUDUGA KEMASUKAN KE PROGRAM IJAZAH PERTAMA BDS SESI AKADEMIK 2020/2021
    02 Jun 2020 - 03 Jun 2020 (Faculty)
  • ASSESSOR FOR ELECTIVE PROJECT (DIA4011) 2019
    10 Dec 2019 - 13 Jan 2020 (Faculty)
  • Panel for phD candidature defence-Farhana Yahya (TRPV4 INVOLVEMENT IN ANGIOGENESIS OF ORAL CANCER IN VIVO MODEL)
    10 Jan 2020 - 10 Jan 2020 (Faculty)
  • Role players for MJDF 2019
    26 Aug 2019 - 27 Aug 2019 (National)
  • PENEMUDUGA KEMASUKAN KE PROGRAM IJAZAH PERTAMA BDS SESI AKADEMIK 2019/2020
    29 May 2019 - 29 May 2019 (Faculty)
  • Ahli Jawatankuasa Keselamatan dan Kesihatan
    09 Feb 2018 - 09 Feb 2019 (Faculty)
  • Assessor for Elective Project
    01 Dec 2018 - 10 Jan 2019 (Faculty)

MEMBERSHIPS

  • UNIVERSITY OF SHEFFIELD, MEMBER
    Since 2017 (University)
  • MEMBER OF TASK FORCE KPI AKADEMIK, MEMBER
    2021 to 2021 (University)
  • MALAYSIAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, MEMBER
    2019 to 2020 (National)
  • ORAL CANCER RESEARCH & COORDINATING CENTRE, COMMITTEE MEMBER
    2018 to 2019 (University)
  • AMERICAN ASSOCIATION FOR CANCER RESEARCH, ACADEMIC MEMBER
    2016 to 2017 (International)
  • GOLDEN KEY INTERNATIONAL HONOUR SOCIETY, MEMBER
    2003 to 2004 (International)

AWARD AND STEWARDSHIP

  • MAKNA Cancer Research Award 2020
    MAKNA & Academy of Science Malaysia, 2020 (National)
  • Terima ijazah phD kurang dari 4 tahun
    Universiti Malaya, 2018 (University)
  • Runner-up of Best Final Year Project 2006
    Universiti Putra Malaysia, 2006 (University)

PUBLICATIONS

Article in Journal
WoS
  1. Abidin, Siti Amalina Inche Zainal; Paterson, Ian Charles; Hunt, Stuart; Lambert, Daniel W.; Higginbotham, Samuel; Pink, Ryan Charles (2021). Myofibroblast transdifferentiation is associated with changes in cellular and extracellular vesicle miRNA abundance, PLOS ONE. 16(11), . doi:10.1371/journal.pone.0256812
Others
  1. Abidin SA, Ian Paterson IC, Hunt S, Lambert DW, Higginbotham S, Pink RC. Myofibroblast transdifferentiation is associated with changes in cellular and extracellular ves.icle miRNA abundance PLOS ONE |2021 https://doi.org/10.1371/journal.pone.0256812.
  2. Melling, G.E., Flannery, S.E., Abidin, S.A. et al. (13 more authors) (2018) A miRNA-145/TGF- 1 Negative Feedback Loop Regulates the Cancer-Associated Fibroblast Phenotype. Carcinogenesis. bgy032. ISSN 0143-3334
  3. Abdullah, S., Abidin, S. A. Z., Murad, N. A., Makpol, S., Ngah, W. Z. W., & Yusof, Y. A. M. (2010). Ginger extract (Zingiber officinale) triggers apoptosis and G0/G1 cells arrest in HCT 116 and HT 29 colon cancer cell lines. African Journal of Biochemistry Research, 4(5), 134-142.
  4. Yaacob, N. S., Hamzah, N., Kamal, N. N. N. M., Abidin, S. A. Z., Lai, C. S., Navaratnam, V., & Norazmi, M. N. (2010). Anticancer activity of a sub-fraction of dichloromethane extract of Strobilanthes crispus on human breast and prostate cancer cells in vitro. BMC complementary and alternative medicine, 10(1), 42.
Other Publications
  1. Sakinah, S, Abdul Majid N, Zainal Abidin, SAI (2021). Comparison of Cilia Frequency and Length in Oral Cancer With Different Metastatic Potentials . - Data Paper

RESEARCH PROJECT

National
  1. 2019 - 2023, Fundamental Research Grant Scheme (FRGS)
    Elucidating The Role Of Primary Cilia In Oral Carcinogenesis ( Principal Investigator(PI))
  2. 2020 - 2023, RU Geran - Fakulti Program
    Investigation Of Anticancer Properties And The Effects Of Melittin On Gene, Protein And Phosphorylation Expressions In Oscc ( Co-Researcher)
  3. 2020 - 2022, RU Geran
    1. Investigating The Role Of Primary Cilia In Metabolic Reprogramming Of Oral Cancer With Different Metastatic Potentials 2. Studies On Association Of Primary Cilia Matrix Metalloproteinase In Oral Cancer ( Principal Investigator(PI))
  4. 2018 - 2020, Bantuan Kecil Penyelidikan (BKP)
    MicroRNA Regulation in Cancer Associated Fibroblasts (CAFs) phenotype ( Principal Investigator(PI))
  5. 2015 - 2018, Geran Penyelidikan Universiti Malaya (UMRG)
    miRNAs signatures indicative of the sensitivity to Vitamin D in oral cancer ( Technical Advisor)
Private
  1. 2021 - 2023, Private Funding
    YYY ( Principal Investigator(PI))
  2. 2021 - 2023, Private Funding
    Investigating The Role Of Primary Cilia In Cancer Associated-fibroblasts (caps) Differentiation ( Principal Investigator(PI))

CONSULTANCY PROJECT

  • Investigation of Anticancer Properties and The Effects of Melittin On Gene, Protein and Phosphorylation Expressions in Oscc, Institute of Biological Sciences
    01 Dec 2020 - 01 Dec 2022 (National)
  • Mirnas Signatures Indicative of The Sensitivity to Vitamin D in Oral Cancer, Oral Cancer Research & Coordinating Centre
    01 Dec 2017 - 01 Dec 2018 (National)

PAPER PRESENTED

ORAL PRESENTER
  1. SC/D-F9 induced apoptosis and caspase 3/7 activation in prostate cancer cells, 36th Malaysian of Biochemistry & Molecular Biology, Malaysian Society of Biochemistry (National) (27 Jul 2011 - 28 Jul 2011)
POSTER PRESENTER
  1. Role of microRNAs in determining the cancer associated fibroblast phenotype, The function of tumour microenvironment in cancer progression, AACR (International) (07 Jan 2016 - 10 Jan 2016)
  2. In vitro antitumour activity of strobilanthes crispus on human cancer cell lines, 14th National Conference on Medical and Health Sciences, Universiti Sains Malaysia (National) (04 May 2009 - 05 May 2009)
OTHERS
  1. 24th Scientific Meeting of The Malaysian Society of Pharmacology & Physiology, None, Universiti Teknologi MARA (National) (02 Jun 2010 - 03 Jun 2010)
  2. None, UK-Malaysia Symposium on Drug Discovery and Development for Cancer, CARIF (National) (08 Feb 2010 - 09 Feb 2010)
  3. None, 2nd Regional Conference on Molecular Medicine, UKM Medical Molecular Biology Institute (UMBI) (National) (08 Oct 2007 - 10 Oct 2007)

ACADEMIC/PROFESSIONAL SERVICES

Evaluation
  1. (2023) Ahli Jawatankuasa Keselamatan dan Kesihatan Pekerjaan (Jkkp), University, (Reviewer)
  2. (2022) Panel Penilai Untuk Pembentangan Seminar Proposal Defence Brenda Leecyous (17012912), University, (Internal Assessor)
  3. (2022) Penyelaras Biobank & Repositori Makmal Penyelidikan, University, (Reviewer)
  4. (2022) Candidature Defence Kathyleen Chong Hui Lin, University, (Internal Assessor)
  5. (2022) Candidature Defence 2: Dr Syarifah Nabilah Syed Mohd Hamdan (Fast Track), University, (Internal Assessor)
  6. (2022) Biomedical Sciences Final Year Project, University, (Internal Assessor)
  7. (2022) Candidature Defence 1: Dr Syarifah Nabilah Syed Mohd Hamdan (Fast Track), University, (Internal Assessor)
  8. (2022) Candidature Defence Nor Flora Nor Ahmad Rajkumar, University, (Internal Assessor)
  9. (2021) Perlantikan Panel Confirmation Defence Bagi Calon Phd Nor Flora Nor Ahmad Rajkumar, University, (Internal Assessor)
  10. (2021) Manuscript Eos-12689-Ra-21 "Role of Primary Cilia in Squamous Cell Carcinoma of Head and Neck Region", International, (Reviewer)
  11. (2021) Interviewer Bds Intake 2021, University, (Internal Assessor)
  12. (2021) The Role of Sphingosine 1-Phosphate Signalling in Mediating Cross-Talk Between Tumour Cells and Fibroblast in Oral Cancer, University, (Internal Assessor)
  13. (2021) Phd Proposal Defence Nor Flora Nor Ahmad Rajkumar, University, (Internal Assessor)
  14. (2021) An Audit On Removable Prosthodontics Cases Completed by Dental Students for The Academic Session Year 2018/2019 in The Faculty of Dentistry, University of Malaya, University, (Internal Assessor)
  15. (2021) 2-Methoxy-1,4-Napthoquinone (Mnq) Induces Autophagy in Triple Negative Breast Cancer Cells, National, (Reviewer)
  16. (2020) Pengerusi panel permohonan pertukaran taraf pencalonan dari program sarjan ke phD-Nurul Jannah Mohd Asngari Title : Interaction Mechanism of Curcuma Purpurascens Extracts and Cysteine Protease Inhibitor, Odanacatib with Human Serum Albumin , (Chairperson)
  17. (2020) Invited reviewer for Asian Pacific Journal of Cancer Prevention , (Reviewer)
  18. (2020) Invited reviewer for journal of Evidence-Based Complementary and Alternative Medicine, (Reviewer)
Contribution to external organisation
  1. (2020) Panel for phD candidature defence- Farhana Yahya, Department of Oral and Craniofacial Sciences, Faculty of Dentistry,UM
Contribution to event
  1. (2021) Webinar, University, (Participant)
  2. (2021) Webinar, University, (Participant)
  3. (2021) Webinar, University, (Participant)
  4. (2021) Ahli Jawatankuasa (Scientific Committee), University, (Event Coordinator)

SUPERVISION

Under Graduate Students
  1. (2022) BIOACTIVITIES OF HYDROXYAPATITE COATED WITH TUALANG HONEY ON MEDICATION-RELATED OSTEONECROSIS OF THE JAW (MRONJ)
  2. (2018) in-vitro anticancer potential of organic extracts of Rhizophora stytosa leaves and barks against oral cancer cell lines (000000362)
Postgraduate Student
PhD/ Doctoral
  1. (2022) role of primary cilia in oral cancer, SAKINAH MAIDEENSA SYED GULAM
  2. (2022) Microbial and host-response salivary biomarkers in response to non-surgical periodontal therapy, WAN NUR ALWANI BINTI WAN ABDUL AZIZ
  3. (2020) role of primary cilia in oral cancer, Sakinah Maideensa Syed Gulam
  4. (2019) The role of primary cilia in oral cancer, Sakinah Maideensa Syed Gulam
Master
  1. (2022) PRIMARY CILIA FREQUENCY AND LENGTH IN CANCER-ASSOCIATED FIBROBLAST (CAFs), Juman Minjal
  2. (2022) Studies on association of primary cilia with matrix metalloproteinase in oral cancer, Jia Shi Liew
  3. (2022) INVESTIGATING THE ROLE OF PRIMARY CILIA IN METABOLIC REPROGRAMMING OF ORAL CANCER WITH DIFFERENT METASTATIC POTENTIALS, Pei Jun Chai

TEACHING

Doctor Of Philosophy
  1. (2022) DXGW6171 - Information & Communication Technology, Research Methodology and Biostatistics
Master
  1. (2021) DXGW6171 -
Bachelor
  1. (2022) DIA1001 - Oral Biology
  2. (2020) DIA1001 - Oral Biology

SOCIAL RESPONSIBILITY ACTIVITIES

  • Donation, (24 Apr 2021 - 30 Apr 2021) (University)
  • Umhakcs 3.0 (Charity Programme), (14 Aug 2020 - 03 Sep 2020)
  • Dental Sports Day 2020, (07 Mar 2020 - 07 Mar 2020)
  • Mouth Cancer Awareness Week 2019, (17 Nov 2019 - 17 Nov 2019)
  • Mouth Cancer Awareness Week Walkhaton, (11 Nov 2018 - 11 Nov 2018)

COURSE ATTENDED

Internal / External Course
EXTERNAL COURSE
  1. CRISPR GENE EDITING WORKSHOP 2019, Ukm Medical Molecular Biology Institute (Umbi), UKM Medical Centre, Jalan Ya Acob Latiff, Bandar Tun Razak, 56000 Cheras, Kuala Lumpur, Malaysia (18 Nov 2019 - 20 Nov 2019)