Curriculum Vitae
BIOGRAPHY
Dr. Ramasamy earned her PhD in Clinical Medicine Research Programme (specialisation: human embryonic stem cell research) from the Department of Surgery and Cancer, Hammersmith Hospital, Imperial College London, UK. She is heading the Stem Cell Biology Laboratory, Department of Molecular Medicine, a research group focussing on Regenerative Medicine, Stem Cell Technology and Cancer Stem Cell research. Her passion for developing and driving industrial partnerships has steered to a number of successful MOAs and collaborative endeavours through her management of, including, Cell & Molecular Biology Laboratory (CMBL), Central Research Laboratories (CRL) Faculty of Medicine (FOM). During her leadership role as head of the Internationalisation Unit, FOM (IUFOM), many collaborative and networking activities were embarked at the national and international arena paving the path towards excellence in the research and academic portfolio of the faculty and university. She also has been serving the Industrial and Community Engagement (UMICE) portfolio as the chief liaison officer for FOM.
Dr. Ramasamy has been actively engaged in stem cell research for more than a decade now and recently embarked on cancer stem cell research, the research field that she has so much passion. Her research group has set their focus to strive for innovative and creative cutting edge research in developing effective stem cell therapy and target cancer stem cells by developing scientific programs of exceptional merit in collaboration with multiple institutions and industries at national and international levels. She has been leading and involved in many research programmes/grants at national and international levels. She has been invited to present the research findings in many national and international meetings as keynote and invited speaker. Her passion for bringing the impact of regenerative research in Malaysia to a great height is very much evident through her leadership role as the President of Tissue Engineering and Regenerative Medicine Society of Malaysia (TESMA) [2015-2019], Advisory Committee for Tissue Engineering and Regenerative Medicine International Society (TERMIS) World Congress 2021 and many other national and international meetings. As the founding advisor of the Malaysian Society for Extracellular Vesicles (MySEV) and Co-founder of the Innovation Forum-Kuala Lumpur (IFKL) Chapter, she is aspired to build the network with international institutions and societies. Collaborative Intelligence is what Dr. Ramasamy firmly believed in.
AREAS OF EXPERTISE
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CANCER STEM CELLSChemoresistance, targeting cancer stem cells, EMT, signalling pathways
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TISSUE ENGINEERING3D culture technology
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REGENERATIVE MEDICINE & STEM CELL THERAPYhepatic & neuronal differentiation, microRNA, epigenetic reprogramming, cell cycle
ACADEMIC QUALIFICATION
- PhD(UK)(2012), (Stem Cell Biology)Imperial College of Science,Technology and Medicine
- B.Sc.(Hons)(Biotechnology)(UPM)(2006), (BIOTECHNOLOGY)Universiti Putra Malaysia (UPM)
ADMINISTRATIVE DUTIES
- Academic advisor for MBBS Phase 1 students (2013/2014)01 Sep 2013 - present (Department of Molecular Medicine, Faculty of Medicine)
- Co-Coordinator, University of Malaya Medical Programme11 Aug 2016 - present (Department of Molecular Medicine, Faculty of Medicine)
- Sub-editor of Journal of Health and Translational Medicine (JUMMEC)29 Apr 2013 - present (Dean Office, Faculty of Medicine)
- Manager, Medical Biotechnology Laboratory 201 Mar 2014 - present (Dean Office, Faculty of Medicine)
- Facilitator : UMAST-Go Soft Skill Programme22 Jan 2013 - present (University Malaya)
- Academic Adviser MBBS Students (2014/2015)01 Sep 2014 - present (Department of Molecular Medicine, Faculty of Medicine)
- Evaluation Committee for 3 Minute Thesis Presentation for Research Methodology Course04 Dec 2023 - 22 Dec 2023 (Faculty)
- Head, Internationalisation Unit01 Jan 2021 - 31 Dec 2022 (Dean Office, Faculty of Medicine)
- Committee member - Breakfast@UMHealth Programme 2021-202202 Jan 2021 - 02 Jan 2022 (University Malaya)
- Chief Liaison Officer PTj Akademik, Universiti Malaya04 Feb 2021 - 31 Dec 2021 (University Malaya)
- Advisory Committee, World Congress of Tissue Engineering and Regenerative Medicine International Society (TERMIS) 202101 Jan 2019 - 31 Dec 2021 (International)
- Deputy Head of Unit, Internationalisation Unit, Dean's office of Medicine01 Apr 2019 - 31 Mar 2021 (University Malaya)
- Manager, Cell & Molecular Biology Laboratory, Central Research Laboratory01 Jan 2020 - 31 Dec 2020 (Dean Office, Faculty of Medicine)
- Scientific Committee, Tissue Engineering and Regenerative Medicine International Society (TERMIS)- Asia Pacific Chapter Meeting 2020 Organising Committee01 Aug 2019 - 31 Dec 2020 (International)
- Examiner, Masters of Clinical Oncology written and viva examination, Session 2020/2021, November 2020, Clinical Oncology Unit, Universiti Malaya Medical Centre01 Jan 2020 - 31 Dec 2020 (University Malaya)
- Interviewer, Universiti Malaya Medical Programme New Intake for Academic Session 2020/2021, Jun 202001 Jan 2020 - 31 Dec 2020 (University Malaya)
- Grant Proposal Reviewer, UMSC CA.R.E Fund (Research Grant) Cycle 1/202001 Jan 2020 - 31 Dec 2020 (Faculty)
- Faculty Representative, University of Malaya STEM Centre01 Oct 2018 - 31 Dec 2020 (University Malaya)
- Chair of Organising Committee, Virtual Meeting between National Cheng Kung University and University Malaya (NCKU-UM) Medical Schools, 14 December 2020 (International)01 Nov 2020 - 15 Dec 2020 (International)
- Advisor, Tissue Engineering and Regenerative Medicine International Society (TERMIS)- Asia Pacific Chapter Meeting 2020 Organising Committee13 Dec 2018 - 24 Sep 2020 (International)
- Coordinator, Science Caf organising committee01 Jan 2018 - 31 Dec 2019 (Dean Office, Faculty of Medicine)
- Research Integrity Committee, Faculty of Medicine (Faculty).31 Mar 2017 - 31 Dec 2018 (Department of Molecular Medicine, Faculty of Medicine)
- Head of Unit01 Jan 2014 - 31 Dec 2018 (Faculty)
- Head of Unit03 Feb 2014 - 31 Dec 2018 (University Malaya)
- Invited Delegate to represent Malaysia and TESMA: TERMIS-Asia Pacific Council Meeting, TERMIS World Congress, 2018 (Japan, September 201801 Sep 2018 - 08 Dec 2018 (International)
- Academic Advisor MBBS Students, Department Of Molecular Medicine, Faculty Of Medicine (Faculty)01 Jun 2015 - 31 May 2018 (Faculty)
- Co-Coordinator, University of Malaya Medical Programme11 Aug 2016 - 30 Mar 2018 (Faculty)
- President, Tissue Engineering & Regenerative Medicine Society of Malaysia (TESMA)13 Aug 2015 - 12 Aug 2017 (National)
- Panel of Interviewer, University Malaya, 21 June 2017.17 Jul 2017 - 21 Jul 2017 (University Malaya)
- Committee Member, Tender Evaluation Committee (Centrifuge) for Cell & Molecular Biology, Faculty of Medicine, Mac 201730 Mar 2017 - 30 Mar 2017 (Faculty)
- Group Coordinator: Community Case Studies Program (Module: Doctor, Patient, Health & Society) MBBS Phase1 (2011/2012)01 Feb 2012 - 30 Dec 2016 (Department of Molecular Medicine, Faculty of Medicine)
- Head of Committee, Tender Evaluation Committee (Biological Safety Cabinet for Cell & Molecular Biology, Faculty of MEdicine)27 Apr 2016 - 27 Apr 2016 (University Malaya)
- Head of Committee, Tender Evaluation Committee (CO2 Incubator for Cell & Molecular Biology, Faculty of Medicine)27 Apr 2016 - 27 Apr 2016 (University Malaya)
- Chief Auditor02 Nov 2015 - 06 Nov 2015 (University Malaya)
- Panel of interviewer11 Aug 2015 - 18 Aug 2015 (University Malaya)
- Committee Member, University Malaya 3-Minute Thesis Competition01 Jun 2015 - 31 Jul 2015 (University Malaya)
- Head of Unit, Medical Biotechnology Laboratory06 Feb 2013 - 28 Feb 2014 (Dean Office, Faculty of Medicine)
MEMBERSHIPS
- ASSOCIATE EDITOR, FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, ASSOCIATE EDITORSince 2021 (International)
- JOURNAL OF HEALTH AND TRANSLATIONAL MEDICINE, BOARD MEMBER2021 to 2023 (International)
- REGENERATIVE RESEARCH (JOURNAL), BOARD MEMBER2019 to 2021 (International)
- EDITOR, JOURNAL OF HEALTH AND TRANSLATIONAL MEDICINE, BOARD MEMBER2019 to 2021 (International)
- TISSUE ENGINEERING AND REGENERATIVE MEDICINE INTERNATIONAL SOCIETY (TERMIS)- ASIA PACIFIC CHAPTER 2020 , ADVISORY BOARD2018 to 2020 (International)
- ONCOTARGETS AND THERAPY , REVIEWER2019 to 2019 (International)
- MOLECULAR MEDICINE REPORTS, REVIEWER2019 to 2019 (International)
- BMC COMPLEMENTARY & ALTERNATIVE MEDICINE , REVIEWER2019 to 2019 (International)
- ACTA ONCOLOGICA , REVIEWER2019 to 2019 (International)
- WORLD JOURNAL OF GASTROENTEROLOGY , REVIEWER2019 to 2019 (International)
- MOLECULAR CARCINOGENESIS , REVIEWER2019 to 2019 (International)
- SCIENTIFIC REPORTS , REVIEWER2019 to 2019 (International)
- TISSUE ENGINEERING & REGENERATIVE MEDICINE SOCIETY OF MALAYSIA (TESMA), PRESIDENT/ CHIEF2017 to 2019 (National)
- SCIENTIFIC REPORTS , ARTICLE REVIEWER2018 to 2018 (International)
- CANCER BIOMARKERS , ARTICLE REVIEWER2018 to 2018 (International)
- BIOSCIENCE REPORTS , ARTICLE REVIEWER2018 to 2018 (International)
- ACTA ONCOLOGICA , ARTICLE REVIEWER2018 to 2018 (International)
- INTERNATIONAL WOUND JOURNAL, ARTICLE REVIEWER2018 to 2018 (International)
- JOURNAL OF NATURAL AGENTS AND MOLECULAR THERAPEUTICS, ARTICLE REVIEWER2018 to 2018 (International)
AWARD AND STEWARDSHIP
- The Global 3Rs AwardIQ Consortium and AAALAC International, 2023 (International)
- Erasmus+ International Credit Mobility Grant (KA107-2020 project)Alliance 4 Universities and Erasmus+ (Programme under European Commision), 2022 (International)
- Fulbright Scholar AwardThe Fulbright Foreign Scholarship Board and Department of State, USA, 2022 (International)
- SATU Joint Research Scheme (International): Project 2- Unravel Metabolic-Stemness Plasticity of CD133+ Liver Cancer Stem Cells Derived from Liver Tumourspheres in Response to Hypoxia (Principal Investigator)SATU , 2020 (International)
- SATU Joint Research Scheme (International): Project 1 -Development of Negative Pressure-Platelet Rich Plasma-Based Wound Treatment for Type 2 Diabetes Mellitus (Principal Investigator)SATU , 2020 (International)
- Invited Meeting with Minister of MOSTI, Malaysia, Discussion with the Minister and sharing of the futuristic plan under MOSTI, June 2020MOSTI, 2020 (National)
- Congratulatory note, Excellent teaching for Problem Based Learning (PBL) evaluation, UMMP PBL Block 8Faculty of Medicine-MERDU, 2020 (Ptj/ Faculty)
- Invited Visiting Scholar- National Cheng Kung University (NCKU) Taiwan, (International)National Cheng Kung University, Taiwan and Taiwan Ministry of Education, 2019 (International)
- Promising Early-Career Scientists Award by Young Leaders ProgramThe New York Academy of Sciences and Science and Technology in Society (STS), 2019 (International)
- EXCELLENCE SERVICE AWARDUniversity of Malaya, 2019 (University)
- Malaysia Convention & Exhibition Bureau (MyCEB) Conference Support Award, Collaboration for conference bidding and promotional activities- Funding and promotional support, Tissue Engineering and Regenerative Medicine International Society Asia Pacific Chapter-TERMIS-AP 2020 (National)Malaysia Convention & Exhibition Bureau (MyCEB) , 2019 (National)
- Marie Sklodowska-Curie Innovative Training Networks (Grant Agreement Number: 813839, call: H2020-MSCA-ITN-2018)-Project Title: Developing novel tools and technologies to assess the safety and efficacy of cell-based regenerative medicine therapies, focusing on kidney disease, Project partner & consultant (International)European Commission , 2019 (International)
- CERTIFICATE OF EXCELLENT SERVICEUniversity of Malaya, 2018 (University)
- Invited Expert Opinion Article in Drug Target Reviews: From fibroblasts to medicinal signalling cells: a paradigm shift in translational stem cell research in collaboration with Dr. Darius Widera, University of Reading, UKDrug Target Reviews, 2018 (International)
- BBSRC Innovation Accelerator Travel Support for Research Leave Project title: A novel bioengineered substrate for human pluripotent stem cell culture, in partnership with Prof Patricia Murray, Institute of Translational Medicine, University of Liverpool, funded by UK BBSRC Research Council Award (International)UK BBSRC Research Council , 2018 (International)
- YSN-ASM Young Investigator Award (Best Poster): Presented by: Ain Zubaidah Ayob, Co-responding author: Dr. Thamil Selvee RamasamyYoung Scientist Network-Academy of Science, 2017 (National)
- Travel Award to Tissue Engineering and Regenerative Medicine International Society-Asia Pacific Meeting (TERMIS-AP 2017)MALAYSIA CONVENTION & EXHIBITION BUREAU (MyCEB), 2017 (International)
- Keystone Symposia Travel Award ( Student: Yew Hong Wen)University of Hong Kong and Keystone Symposia, 2017 (International)
- Keystone Symposia Travel AwardUniversity of Hong Kong and Keystone Symposia, 2017 (International)
- Best Poster Award -3rd Prize, Central Research Laboratories? Open Day 2016Faculty of Medicine, 2016 (University)
- Best Poster Award -2nd Prize, Central Research Laboratories? Open Day 2016University of Malaya, 2016 (University)
- Best Poster Award-1st Prize, Central Research Laboratories? Open Day 2016Faculty of Medicine, 2016 (University)
- BBSRC Impact Acceleration Award (collaborative project/award with University of Liverpool, UK)BBSRC UK Research Council, 2016 (International)
- CERTIFICATE OF EXCELLENT SERVICEUniversity of Malaya, 2016 (University)
- Certificate of Appreciation: Organising Chair & Speaker of TESMA Seminar Series 2015Tissue Engineering and Regenerative Medicine Society of Malaysia, 2015 (National)
- Certificate of Appreciation:Judge, 45th Malaysian Orthopaedic Association Annual Scientific Meeting, May 2015Malaysian Orthopaedic Association, 2015 (International)
- Fluidigm/Chemosciece Sponsored project AwardFluidigm Technology/Chemosciece, 2015 (National)
- Appreciation for External Examination Moderator: Msc (Regenerative Medicine)-UCSI UniversityUCSI University, 2014 (National)
- Certificate of Appreciation:Judge, 44th Malaysian Orthopaedic Association Annual Scientific Meeting, May 2014Malaysian Orthopaedic Association, 2014 (International)
- Best Poster Presentation Award (1st Prize) at 1St National Stem Cell CongressMinistry of Health & UKM Medical Molecular Biology Institute, Malaysia, 2012 (National)
- Scientific Meeting travel award: United Kingdom Stem Cell Network (UKSCN) Annual National Meeting (York, UK, 30th March-1st April 2011)Genesis Research Trust, London, 2011 (University)
- Conference Travel Award: The 16th International Conference of the International Society of Differentiation: From Stem Cell to Organisms (Nara, Japan 15-18 November 2010)International Society of Differentiation, 2010 (International)
- SLAI PhD ScholarshipMinistry of Higher Education, 2007 (National)
- Excellent Academic Achievement Award (Overall-Faculty & University)UPM, 2006 (University)
PUBLICATIONS
Article in Journal
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Sawai, Sakunie; Wong, Pooi-Fong; Ramasamy, Thamil Selvee (2022). Hypoxia-regulated microRNAs: the molecular drivers of tumor progression, CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY. . doi:10.1080/10409238.2022.2088684
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Ayob, A. Z., & Ramasamy, T. S. (2021). Prolonged hypoxia switched on cancer stem cell-like plasticity in HepG2 tumourspheres cultured in serum-free media. In Vitro Cellular & Developmental Biology-Animal, 57(9), 896-911. doi: 10.1007/s11626-021-00625-y
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Ong, A. L. C., Lee, S. H., Aung, S. W., Khaing, S. L., & Ramasamy, T. S. (2021). 5-Azacytidine pretreatment confers transient upregulation of proliferation and stemness in human mesenchymal stem cells. Cells & Development, 165, 13. doi: 10.1016/j.cdev.2021.203659
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Ramasamy, T. S., Yee, Y. M., & Khan, I. M. (2021). Chondrocyte Aging: The Molecular Determinants and Therapeutic Opportunities. Frontiers in Cell and Developmental Biology, 9, 14. doi: 10.3389/fcell.2021.625497
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Wong, M. M. T., Chan, H. Y., Aziz, N. A., Ramasamy, T. S., Bong, J. J., Ch'ng, E. S., . . . Teow, S. Y. (2021). Interplay of autophagy and cancer stem cells in hepatocellular carcinoma. Molecular Biology Reports, 48(4), 3695-3717. doi: 10.1007/s11033-021-06334-9
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Yadav, A., Huang, T. C., Chen, S. H., Ramasamy, T. S., Hsueh, Y. Y., Lin, S. P., . . . Wu, C. C. (2021). Sodium phenylbutyrate inhibits Schwann cell inflammation via HDAC and NF kappa B to promote axonal regeneration and remyelination. Journal of Neuroinflammation, 18(1), 16. doi: 10.1186/s12974-021-02273-1
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Aung, S. W., Abu Kasim, N. H., Shamsuddin, S. A. A., Ramasamy, T. S. (2020). MicroRNAomic Transcriptomic Analysis Reveal Deregulation of Clustered Cellular Functions in Human Mesenchymal Stem Cells During in Vitro Passaging. Stem Cell Reviews and Reports, 16(1), 222-238. doi: 10.1007/s12015-019-09924-0
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Aung, Shuh-Wen; Abu Kasim, Noor Hayaty; Shamsuddin, Shamsul Azlin Ahmad; Ramasamy, Thamil Selvee (2020). MicroRNAomic Transcriptomic Analysis Reveal Deregulation of Clustered Cellular Functions in Human Mesenchymal Stem Cells During in Vitro Passaging (vol 16, pg 222, 2020), STEM CELL REVIEWS AND REPORTS. 16(4), 809-810. doi:10.1007/s12015-020-09968-7
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Aung, Shuh-Wen; Abu Kasim, Noor Hayaty; Shamsuddin, Shamsul Azlin Ahmad; Ramasamy, Thamil Selvee (2020). MicroRNAomic Transcriptomic Analysis Reveal Deregulation of Clustered Cellular Functions in Human Mesenchymal Stem Cells During in Vitro Passaging, STEM CELL REVIEWS AND REPORTS. 16(1), 222-238. doi:10.1007/s12015-019-09924-0
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Lee, S. H., Reed-Newman, T., Anant, S., & Ramasamy, T. S. (2020). Regulatory Role of Quiescence in the Biological Function of Cancer Stem Cells. Stem Cell Reviews and Reports, 16(6), 1185-1207. doi: 10.1007/s12015-020-10031-8
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Aung, Shuh-Wen; Abu Kasim, Noor Hayaty; Ramasamy, Thamil Selvee (2019). Isolation, Expansion, and Characterization of Wharton's Jelly-Derived Mesenchymal Stromal Cell: Method to Identify Functional Passages for Experiments, STEM CELLS AND AGING, 2 EDITION. 2045, 323-335. doi:10.1007/7651_2019_242
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Bindal, P., Gnanasegaran, N., Bindal, U., Haque, N., Ramasamy, T. S., Chai, W. L., Abu Kasim, N. H. (2019). Angiogenic effect of platelet-rich concentrates on dental pulp stem cells in inflamed microenvironment. Clinical Oral Investigations, 23(10), 3821-3831. doi: 10.1007/s00784-019-02811-5
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Bindal, Priyadarshni; Gnanasegaran, Nareshwaran; Bindal, Umesh; Haque, Nazmul; Ramasamy, Thamil Selvee; Chai, Wen Lin; Abu Kasim, Noor Hayaty (2019). Angiogenic effect of platelet-rich concentrates on dental pulp stem cells in inflamed microenvironment, CLINICAL ORAL INVESTIGATIONS. 23(10), 3821-3831. doi:10.1007/s00784-019-02811-5
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Gunawardena, T. N. A., Masoudian, Z., Rahman, M. T., Ramasamy, T. S., Ramanathan, A., Abu Kasim, N. H. (2019). Dental derived stem cell conditioned media for hair growth stimulation. Plos One, 14(5), 18. doi:10.1371/journal.pone.0216003
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Gunawardena, Tarini Nawamalie Abeysinghe; Masoudian, Zeinab; Rahman, Mohammad Tariqur; Ramasamy, Thamil Selvee; Ramanathan, Anand; Abu Kasim, Noor Hayaty (2019). Dental derived stem cell conditioned media for hair growth stimulation, PLOS ONE. 14(5). doi:10.1371/journal.pone.0216003
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Haque, Nazmul; Ramasamy, Thamil Selvee; Abu Kasim, Noor Hayaty (2019). Mechanisms of Mesenchymal Stem Cells for Autoimmune Disease Treatment, STEM CELL TRANSPLANTATION FOR AUTOIMMUNE DISEASES AND INFLAMMATION. , 27-44. doi:10.1007/978-3-030-23421-8_2
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Rothan, H. A., Ambikabothy, J., Ramasamy, T. S., Rashid, N. N., Yusof, R. (2019). A Preliminary Study in Search of Potential Peptide Candidates for a Combinational Therapy with Cancer Chemotherapy Drug. International Journal of Peptide Research and Therapeutics, 25(1), 115-122. doi:10.1007/s10989-017-9646-9
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Rothan, Hussin A.; Ambikabothy, Jamunaa; Ramasamy, Thamil Selvee; Rashid, Nurshamimi Nor; Yusof, Rohana (2019). A Preliminary Study in Search of Potential Peptide Candidates for a Combinational Therapy with Cancer Chemotherapy Drug, INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS. 25(1), 115-122. doi:10.1007/s10989-017-9646-9
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Samuel, S., Ahmad, R. E., Ramasamy, T. S., Karunanithi, P., Naveen, S. V., Kamarul, T. (2019). Platelet-rich concentrate in serum-free medium enhances cartilage-specific extracellular matrix synthesis and reduces chondrocyte hypertrophy of human mesenchymal stromal cells encapsulated in alginate. Platelets, 30(1), 66-74. doi:10.1080/09537104.2017.1371287
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Samuel, Shani; Ahmad, Raja Elina; Ramasamy, Thamil Selvee; Karunanithi, Puvanan; Naveen, Sangeetha Vasudevaraj; Kamarul, Tunku (2019). Platelet-rich concentrate in serum-free medium enhances cartilage-specific extracellular matrix synthesis and reduces chondrocyte hypertrophy of human mesenchymal stromal cells encapsulated in alginate, PLATELETS. 30(1), 66-74. doi:10.1080/09537104.2017.1371287
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Ayob, Ain Zubaidah; Ramasamy, Thamil Selvee (2018). Cancer stem cells as key drivers of tumour progression, JOURNAL OF BIOMEDICAL SCIENCE. 25. doi:10.1186/s12929-018-0426-4
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Bindal, Priyadarshini; Ramasamy, Thamil Selvee; Abu Kasim, Noor Hayaty; Gnanasegaran, Nareshwaran; Chai, Wen Lin (2018). Immune responses of human dental pulp stem cells in lipopolysaccharide-induced microenvironment, CELL BIOLOGY INTERNATIONAL. 42(7), 832-840. doi:10.1002/cbin.10938
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Kalra, Kunal; Chandrabose, Srijaya Thekkeparambil; Ramasamy, Thamil Selvee; Abu Kasim, Noor Hayaty Binti (2018). Advances in the Generation of Functional beta-cells from Induced Pluripotent Stem Cells As a Cure for Diabetes Mellitus, CURRENT DRUG TARGETS. 19(13), 1463-1477. doi:10.2174/1389450119666180605112917
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Ong, Agnes L. C.; Ramasamy, Thamil Selvee (2018). Role of Sirtuin1-p53 regulatory axis in aging, cancer and cellular reprogramming, AGEING RESEARCH REVIEWS. 43, 64-80. doi:10.1016/j.arr.2018.02.004
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Ramasamy, Thamil Selvee; Ong, Agnes Lee Chen; Cui, Wei (2018). Impact of Three-Dimentional Culture Systems on Hepatic Differentiation of Puripotent Stem Cells and Beyond, NOVEL BIOMATERIALS FOR REGENERATIVE MEDICINE. 1077, 41-66. doi:10.1007/978-981-13-0947-2_4
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Ramasamy, Thamil Selvee; Velaithan, Vithya; Yeow, Yelena; Sarkar, Fazlul H. (2018). Stem Cells Derived from Amniotic Fluid: A Potential Pluripotent-Like Cell Source for Cellular Therapy?, CURRENT STEM CELL RESEARCH & THERAPY. 13(4), 252-264. doi:10.2174/1574888X13666180115093800
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Samuel, Shani; Ahmad, Raja Elina; Ramasamy, Thamil Selvee; Manan, Faizal; Kamarul, Tunku (2018). Platelet rich concentrate enhances mesenchymal stem cells capacity to repair focal cartilage injury in rabbits, INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED. 49(4), 775-783. doi:10.1016/j.injury.2018.02.020
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Sawai, Sakunie; Mohktar, Masa Sahidayana; Safwani, Wan Kamarul Zaman Wan; Ramasamy, Thamil Selvee (2018). Suppression of the Viability and Proliferation of HepG2 Hepatocellular Carcinoma Cell Line by Konjac Glucomannan, ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY. 18(9), 1258-1266. doi:10.2174/1871520618666180307143229
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Sundararajan, Vignesh; Sarkar, Fazlul H.; Ramasamy, Thamil Selvee (2018). The versatile role of exosomes in cancer progression: diagnostic and therapeutic implications (vol 41, pg 223, 2018), CELLULAR ONCOLOGY. 41(4), 463-463. doi:10.1007/s13402-018-0396-2
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Sundararajan, Vignesh; Sarkar, Fazlul H.; Ramasamy, Thamil Selvee (2018). The versatile role of exosomes in cancer progression: diagnostic and therapeutic implications, CELLULAR ONCOLOGY. 41(3), 223-252. doi:10.1007/s13402-018-0378-4
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Bindal, Priyadarshni; Abu Kasim, Noor H.; Ramasamy, Thamil Selvee; Dabbagh, Ali; Moharamzadeh, Keyvan; Chai, Wen L. (2017). Dental pulp tissue engineering and regenerative endodontic therapy, BIOMATERIALS FOR ORAL AND DENTAL TISSUE ENGINEERING. , 297-318. doi:10.1016/B978-0-08-100961-1.00018-9
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Bindal, Priyadarshni; Bindal, Umesh; Lin, Chai Wen; Abu Kasim, Noor Hayaty; Ramasamy, Thamil Selvee A. P.; Dabbagh, Ali; Salwana, Ely; Shamshirband, Shahaboddin (2017). Neuro-fuzzy method for predicting the viability of stem cells treated at different time-concentration conditions, TECHNOLOGY AND HEALTH CARE. 25(6), 1041-1051. doi:10.3233/THC-170922
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Mahmod, Suhaeb A.; Snigh, Simmrat; Djordjevic, Ivan; Yee, Yong Mei; Yusof, Rohana; Ramasamy, Thamil Selvee; Rothan, Hussin A. (2017). Phytoestrogen (Daidzein) Promotes Chondrogenic Phenotype of Human Chondrocytes in 2D and 3D Culture Systems, TISSUE ENGINEERING AND REGENERATIVE MEDICINE. 14(2), 103-112. doi:10.1007/s13770-016-0004-3
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Chiew, Seet Khing; Ramasamy, Thamil Selvee; Amini, Farahnaz (2016). Effectiveness and relevant factors of platelet-rich plasma treatment in managing plantar fasciitis: A systematic review, JOURNAL OF RESEARCH IN MEDICAL SCIENCES. 21
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Liau, Mooi Tiong; Amini, Farahnaz; Ramasamy, Thamil Selvee (2016). The therapeutic potential of stem cells and progenitor cells for the treatment of Parkinson's disease, TISSUE ENGINEERING AND REGENERATIVE MEDICINE. 13(5), 455-464. doi:10.1007/s13770-016-9093-2
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Samuel, Shani; Ahmad, Raja Elina; Ramasamy, Thamil Selvee; Karunanithi, Puvanan; Naveen, Sangeetha Vasudevaraj; Murali, Malliga Raman; Abbas, Azlina A.; Kamarul, Tunku (2016). Platelet-rich concentrate in serum free medium enhances osteogenic differentiation of bone marrow-derived human mesenchymal stromal cells, PEERJ. 4. doi:10.7717/peerj.2347
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Ramasamy, Thamil Selvee; Ayob, Ain Zubaidah; Myint, Hsu Hsu Lynn; Thiagarajah, Sharmanee; Amini, Farahnaz (2015). Targeting colorectal cancer stem cells using curcumin and curcumin analogues: insights into the mechanism of the therapeutic efficacy, CANCER CELL INTERNATIONAL. 15. doi:10.1186/s12935-015-0241-x
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Yu, Jason S. L.; Ramasamy, Thamil Selvee; Murphy, Nick; Holt, Marie K.; Czapiewski, Rafal; Wei, Shi-Khai; Cui, Wei (2015). PI3K/mTORC2 regulates TGF-beta/Activin signalling by modulating Smad2/3 activity via linker phosphorylation, NATURE COMMUNICATIONS. 6. doi:10.1038/ncomms8212
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Srijaya, Thekkeparambil Chandrabose; Ramasamy, Thamil Selvee; Abu Kasim, Noor Hayaty (2014). Advancing stem cell therapy from bench to bedside: lessons from drug therapies, JOURNAL OF TRANSLATIONAL MEDICINE. 12. doi:10.1186/s12967-014-0243-9
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Ramasamy, Thamil Selvee; Yu, Jason S. L.; Selden, Clare; Hodgson, Humphery; Cui, Wei (2013). Application of Three-Dimensional Culture Conditions to Human Embryonic Stem Cell-Derived Definitive Endoderm Cells Enhances Hepatocyte Differentiation and Functionality, TISSUE ENGINEERING PART A. 19(3-4), 360-367. doi:10.1089/ten.tea.2012.0190
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Moschidou, Dafni; Mukherjee, Sayandip; Blundell, Michael P.; Drews, Katharina; Jones, Gemma N.; Abdulrazzak, Hassan; Nowakowska, Beata; Phoolchund, Anju; Lay, Kenneth; Ramasamy, T. Selvee; Cananzi, Mara; Nettersheim, Daniel; Sullivan, Mark; Frost, Jennifer; Moore, Gudrun; Vermeesch, Joris R.; Fisk, Nicholas M.; Thrasher, Adrian J.; Atala, Anthony; Adjaye, James; Schorle, Hubert; De Coppi, Paolo; Guillot, Pascale V. (2012). Valproic Acid Confers Functional Pluripotency to Human Amniotic Fluid Stem Cells in a Transgene-free Approach, MOLECULAR THERAPY. 20(10), 1953-1967. doi:10.1038/mt.2012.117
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Noisa, Parinya; Ramasamy, Thamil Selvee; Lamont, Fiona R.; Yu, Jason S. L.; Sheldon, Michael J.; Russell, Alison; Jin, Xin; Cui, Wei (2012). Identification and Characterisation of the Early Differentiating Cells in Neural Differentiation of Human Embryonic Stem Cells, PLOS ONE. 7(5). doi:10.1371/journal.pone.0037129
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Rothan, Hussin A.; Han, Heh Choon; Ramasamy, Thamil Selvee; Othman, Shatrah; Abd Rahman, Noorsaadah; Yusof, Rohana (2012). Inhibition of dengue NS2B-NS3 protease and viral replication in Vero cells by recombinant retrocyclin-1, BMC INFECTIOUS DISEASES. 12. doi:10.1186/1471-2334-12-314
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Ramasamy, Thamil Selvee; Cui, Wei (2010). Inhibition of phosphatidylinositol-3-kinase signalling promotes Activin A induced definitive endoderm differentiation of human embryonic stem cells, DIFFERENTIATION. 80, S25-S25. doi:10.1016/j.diff.2010.09.032
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Chan HY, Ramasamy TS, Chung FF, Teow SY. Role of sirtuin 1 (SIRT1) in regulation of autophagy and nuclear factor-kappa Beta (NF- β) pathways in sorafenib-resistant hepatocellular carcinoma (HCC). Cell Biochem Biophys. 2024 Mar 11. doi: 10.1007/s12013-024-01247-3.
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Wong PF, Dharmani M, Ramasamy TS*. Senotherapeutics for mesenchymal stem cell senescence and rejuvenation. Drug Discov Today. 2023 Jan;28(1):103424. doi: 10.1016/j.drudis.2022.103424. Epub 2022 Nov 1. PMID: 36332835.
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Chua JKE, Lim J, Foong LH, Mok CY, Tan HY, Tung XY, Ramasamy TS, Govindasamy V, Then KY, Das AK, Cheong SK. Mesenchymal Stem Cell-Derived Extracellular Vesicles: Progress and Remaining Hurdles in Developing Regulatory Compliant Quality Control Assays. Adv Exp Med Biol. 2022;1401:191-211. doi: 10.1007/5584_2022_728. PMID: 35816249.
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Hon HN, Ho PY, Lee JW, Mahmud NAA, Munir HB, Ramasamy TS, Govindasamy V, Then KY, Das AK, Cheong SK. An Affordable Approach of Mesenchymal Stem Cell Therapy in Treating Perianal Fistula Treatment. Adv Exp Med Biol. 2022;1401:73-95. doi: 10.1007/5584_2022_716. PMID: 35781218.
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Yadav A, Ramasamy TS, Lin SC, Chen SH, Lu J, Liu YH, Lu FI, Hsueh YY, Lin SP, Wu CC. Autologous Platelet-Rich Growth Factor Reduces M1 Macrophages and Modulates Inflammatory Microenvironments to Promote Sciatic Nerve Regeneration. Biomedicines. 2022 Aug 17;10(8):1991. doi: 10.3390/biomedicines10081991. PMID: 36009539; PMCID: PMC9406033.
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Yadav A, Huang TC, Chen SH, Ramasamy TS, Hsueh YY, Lin SP, Lu FI, Liu YH, Wu CC. Sodium phenylbutyrate inhibits Schwann cell inflammation via HDAC and NF B to promote axonal regeneration and remyelination. J Neuroinflammation. 2021 Oct 16;18(1):238. doi: 10.1186/s12974-021-02273-1.
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Kwan Hoong Ng, Deming Chau, Thamil Selvee Ramasamy (2020). Introducing Molecular Biology to Medical Physicists, Medical Physics International Journal, Vol.8, No.2, 2020
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RAMASAMY, Thamil Selvee. Stem Cell & Cancer Symposium (SCCS) (2020). Journal of Health and Translational Medicine, [S.l.], p. 1 - 36, oct. 2020. ISSN 2289-392X. Available at: . Date accessed: 30 dec. 2020.
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Aung SW., Abu Kasim N.H., Ramasamy T.S.* (2019) Isolation, Expansion, and Characterization of Wharton s Jelly-Derived Mesenchymal Stromal Cell: Method to Identify Functional Passages for Experiments. In: . Methods in Molecular Biology. Humana Press (https://doi.org/10.1007/7651_2019_242)
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Bindal, P., Gnanasegaran, N., Bindal, U., Haque, N., Ramasamy, T.S., Chai, W.L., Kasim, N.H.A. (2019). Angiogenic effect of platelet-rich concentrates on dental pulp stem cells in inflamed microenvironment. Clin Oral Investig. 23(10): 3821-3831.
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Gounder SS, Ramasamy TS, Ab Rahim S, Subramani B (2019) Enhancement of NK Cell-Mediated Lysis of Osteosarcoma Cells by Up-Regulating the NKG2D Ligands using Spironolactone and Avemar. International Journal of Critical Care and Emergency Medicine 5:089. doi.org/10.23937/2474-3674/1510089
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Jonathan Sheard, Thamil Selvee Ramasamy, Darius Widera (2018). From fibroblasts to medicinal signalling cells: a paradigm shift in translational stem cell research. Drug Target Review 2018.
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Kunal Kalra, Srijaya Thekkeparambil Chandrabose, Thamil Selvee Ramasamy, Noor Hayaty Binti Abu Kasim (2018). Advances in generation of functional -cells from induced pluripotent stem cells as a cure for diabetes mellitus. Current Drug Targets. 2018 Jun 4. doi: 10.2174/1389450119666180605112917.
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P Bindal, TS Ramasamy, NHA Kasim, N Gnanasegaran, CW Lin (2018). Immune responses of human dental pulp stem cells in lipopolysaccharide induced microenvironment. Cell biology international
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Hussin A. RothanEmail authorJamunaa AmbikabothyThamil Selvee RamasamyNurshamimi Nor RashidRohana Yusof. A Preliminary Study in Search of Potential Peptide Candidates for a Combinational Therapy with Cancer Chemotherapy Drug. Int. Journal of Peptide Research and Therapeutics,https://doi.org/10.1007/s10989-017-9646-9
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Samuel S, Ahmad RE, Ramasamy TS, Karunanithi P, Naveen SV, Kamarul T. (2017). Platelet-rich concentrate in serum-free medium enhances cartilage-specific extracellular matrix synthesis and reduces chondrocyte hypertrophy of human mesenchymal stromal cells encapsulated in alginate. Platelets. 2017 Nov 1:1-9. doi: 10.1080/09537104.2017.1371287
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Kim DLP, Ramasamy TS, Amini F (2016). Knowledge, awareness and perception of stem cells research amongst Malaysian medical students. Regenerative Research 4(2) 2016 27-33.
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Mooi Tiong Liau, Farahnaz Amini, Thamil Selvee Ramasamy (2015). The therapeutic potential of stem cells and progenitor cells for the treatment of Parkinson s disease. Tissue Engineering and Regenerative Medicine (accepted)
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Seet Khing Chiew, Thamil Selvee Ramasamy, Farahnaz Amini (2016). Effectiveness and relevant factors of platelet rich plasma treatment in managing plantar faciitis: A systematic review. Journal of Research in Medical Sciences 21 (3)
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Shani Samuel, Raja Elina Ahmad, Thamil Selvee Ramasamy, Puvanan Karunanithi, Sangeetha Vasudevaraj Naveen, Malliga Raman Murali, Azlina A Abbas, Tunku Kamarul (2016). Platelet-rich concentrate in serum free medium enhances osteogenic differentiation of bone marrow-derived human mesenchymal stromal cells. PeerJ 4:e234
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Suhaeb A. Mahmod1, Simmrat Snigh1, Ivan Djordjevic3, Rohana Yusof2, Thamil Selvee Ramasamy2* and Hussin A. Rothan2*. Phytoestrogen (daidzein) promotes chondrogenic phenotype of human chondrocytes in 2D and 3D culture systems. Tissue Engineering and Regenerative Medicine (accepted)
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Thamil Selvee Ramasamy*, Yee Yong Mei, Ilyas Khan, Raja Elina Ahmad, Hema Paramananthan, Farahnaz Amini, Tunku Kamarul. Platelet-rich plasma for cartilage repair: its role in chondrogenesis and treatment of osteoarthritis (under revision). European Cell & Materials
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Amini F, Abiri F, Ramasamy TS, Tan ESS(2015). The efficacy of platelet rich concentrates in skin rejuvenation. Acta Dermatovenerologica Croatica (under revision)
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Jamunaa Ambikabothy , Hussin A. Rothan, Thamil Selvee Ramasamy, Noorsaadah A.Rahman and Rohana Yusof. Combinational therapy of antimicrobial peptides and cancer chemotherapy drug: a preliminary study in search of potential peptide candidates as chemotherapy drug delivery vehicles. International Journal of Peptide Research and Therapeutics (revision)
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Jason Yu, Thamil Selvee Ramasamy, Nick Murphy, Marie Holt, Rafal Czapiewski,Shi-Khai Wei&Wei Cui (2015). PI3K/mTORC2 regulates TGF /Activin signalling by modulating Smad2/3 activity via linker phosphorylation. NATURE Communications 6:7212
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Norman Bin Mohd Norawai, Thamil Selvee Ramasamy, Farahnaz Amini.Treatment of chronic and acute diabetic foot ulcer using combination of Platelet Rich Plasma: Report of two cases. Alternative Therapies in Health and Medicine (under review)
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Shani Samuel, Raja Elina Ahmad, Thamil Selvee Ramasamy, Puvanan Karunanithi, Sangeetha Vasudevaraj Naveen, Malliga Raman Murali, Azlina A Abbas, Tunku Kamarul. Isolated effect of Platelet Rich Concentrate in Augmenting Osteogenic Differentiation of Mesenchymal Stromal Cell for Maxillofacial Reconstructions. Journal of Cranio-Maxillofacial Surgery (under review)
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Yew CH, Ramasamy TS, Amini F (2015). Response to Intradermal Autologous Platelet Rich Plasma Injection in Refactory Dermal Melasma: Report of Two Cases. Journal of Health and translational Medicine JUMMEC 2015:18(2)
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Ramasamy TS (2014). Toward Personalised Cell Therapies: Human Pluripotent Stem Cells as A Research and Therapeutic Tool for liver Diseases. Regenerative Research 3(2) 2014 20-21
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Thamil Selvee Ramasamy, Clare Selden, Humphrey Hodgson, Wei Cui (2014). A comprehensive Culture System Recapitulating In Vivo Liver Development. Regenerative Research 3(2) 2014 150-151
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Ramasamy TS, Yu J, Selden C, Hodgson H, Cui W. (2013). Application of three-dimensional culture conditions to human embryonic stem cell-derived definitive endoderm cells enhances hepatocyte differentiation and functionality. Tissue Engineering Part A. Feb 2013.
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Moschidou D, Mukherjee S, Blundell MP, Drews K, Jones GN, Abdulrazzak H, Nowakowska B, Phoolchund A, Lay K, Ramasamy TS, Cananzi M, Nettersheim D, Sullivan M, Frost J, Moore G, Vermeesch JR, Fisk NM, Thrasher AJ, Atala A, Adjaye J, Schorle H, De Coppi P, Guillot PV. (2012). Valproic Acid Confers Functional Pluripotency to Human Amniotic Fluid Stem Cells in a Transgene-free Approach. Molecular Therapy. 2012 Jul 3.
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Noisa P; Ramasamy TS; Lamont FR; Yu JS; Sheldon MJ; Russell A; Jin X; Cui W. (2012). Identification and characterisation of the early differentiating cells in neural differentiation of human embryonic stem cells. PLoS One. 2012;7(5):e37129. Epub 2012 May 15.
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Ramasamy TS; Cui W. (Nov 2010). Inhibition of phosphatidylinositol-3-kinase signalling promotes Activin A induced definitive endoderm differentiation of human embryonic stem cells. DIFFERENTIATION[Proceedings of Abstracts] Vol 80;1;S25-S25.
Chapter in Books
- Chua JKE, Lim J, Foong LH, Mok CY, Tan HY, Tung XY, Ramasamy TS, Govindasamy V, Then KY, Das AK, Cheong SK. Mesenchymal Stem Cell-Derived Extracellular Vesicles: Progress and Remaining Hurdles in Developing Regulatory Compliant Quality Control Assays. In: Turksen, K. (eds) Cell Biology and Translational Medicine, Volume 17. Advances in Experimental Medicine and Biology(), vol 1401 :191-211.Springer, Cham. https://doi.org/10.1007/5584_2022_728
- Hon HN, Ho PY, Lee JW, Mahmud NAA, Munir HB, Ramasamy TS, Govindasamy V, Then KY, Das AK, Cheong SK. An Affordable Approach of Mesenchymal Stem Cell Therapy in Treating Perianal Fistula Treatment. In: Turksen, K. (eds) Cell Biology and Translational Medicine, Volume 17. Advances in Experimental Medicine and Biology(), vol 1401:73-95. Springer, Cham. https://doi.org/10.1007/5584_2022_716.
- Ramasamy T.S., Ong A.L.C., Cui W. (2018) Impact of Three-Dimensional Culture Systems on Hepatic Differentiation of Pluripotent Stem Cells and Beyond. In: Chun H., Park K., Kim CH., Khang G. (eds) Novel Biomaterials for Regenerative Medicine. Advances in Experimental Medicine and Biology, vol 1077. Springer, Singapore (DOI: https://doi.org/10.1007/978-981-13-0947-2_4)
- Bindal, P., Abu Kasim, N.H., Ramasamy, T.S.A.P., Dabbagh, A., Moharamzadeh, K., Lin, C.W. (2017). Dental pulp tissue engineering and regenerative endodontic therapy. In L. Tayebi & K. Moharamzadeh (Eds), Biomaterials for Oral and Dental Tissue Engineering (pp. 297-318). Elsevier.
Article in Proceeding
- Ramasamy TS; Cui W. (1 Nov 2010). Inhibition of phosphatidylinositol-3-kinase signalling promotes Activin A induced definitive endoderm differentiation of human embryonic stem cells. DIFFERENTIATION. 80:S25- S25.
RESEARCH PROJECT
National
- 2022 - 2025, Fundamental Research Grant Scheme (FRGS)Mitigation Of Accelerated Immunologic Ageing In Childhood Cancer Survivors By Increasing Nicotinamide Adenine Dinucleotide (NAD+) Bioavailability For Sirtuin 1 Through CD38 Catalytic Inhibition ( Co-Researcher)
- 2019 - 2024, Fundamental Research Grant Scheme (FRGS)Investigation Of Pi3k/mtor/beclin Axis In Annexin A1 Regulated Apoptosis-autophagy Switch In Chemoresistant Colorectal Cancer Stem-like Model ( Co-Researcher)
- 2022 - 2024, UM International Collaboration GrantUnravel Metabolic-Stemness Plasticity of Liver Cancer Stem Cells in Response to Cellular Stressors ( Principal Investigator(PI))
- 2019 - 2023, Fundamental Research Grant Scheme (FRGS)Regulatory Mechanism Of Sirt1-p53-mirna Axis In Acquisition Of Cancer Stemness In Hepatocellular Carcinoma Tumourspheres Cultured Under Hypoxic Tumour Niche ( Principal Investigator(PI))
- 2020 - 2023, Others MOHE - Top 100 (IIRG)-FNWIdentification Of Senotherapeutics For Vascular Aging ( Co-Researcher)
- 2020 - 2022, RU GeranRole Probiotics And Gut Microbiota In Colorectal Cancer Prevention ( Co-Researcher)
- 2019 - 2021, Others MOHE - Top 100 (IIRG)-HWBThe Development Of Health Management App Incorporating Speech-based Interaction For The Older Adults ( Co-Researcher)
- 2019 - 2019, RU Geran - Fakulti ProgramInvestigation Of Annexin A1 Regulated Apoptosis-autophagy Switch In Chemoresistant Colorectal Cancer Stem-like Model ( Co-Researcher)
- 2014 - 2018, Geran Penyelidikan Universiti Malaya (UMRG Programme) - HTM (Wellness)Cell-based Models For Regenerative Medicine, Disease Modelling & Drug Discovery Applications ( Principal Investigator(PI))
- 2014 - 2018, Fundamental Research Grant Scheme (FRGS)Investigation Of The Fundamental Role Of Pi3k/akt Signalling Pathway In Inducing Human Embryonic Stem Cell Differentiation Into Definitive Endoderm Via Modulation Of Cell Cycle State ( Principal Investigator(PI))
- 2012 - 2015, Geran Penyelidikan Universiti Malaya (UMRG) - HTM (Wellness)In Vitro Hepatic Differentiation Of Stem Cells/c-kit Positive Cells Derived From Full-term Amniotic Fluid ( Principal Investigator(PI))
- 2015 - 2015, Geran Penyelidikan Universiti Malaya (UMRG Programme) - HTM (Wellness)Extracellular Matrix Microenvironment For Human Pluripotent Stem Cells Survival And Directed Chondrogenic Differentiation ( Principal Investigator(PI))
- 2019 - 2024, Long Term Research Grant Scheme (LRGS)Decoding Phenome to Unravel the Mechanisms of Cognitive Frailty , Universiti Teknologi Mara (UITM) ( Co-Researcher)
- 2019 - 2022, Fundamental Research Grant Scheme (FRGS)Understanding the molecular regulation of Sirtuin1-p53 axis in hypoxic HepG2 for the development of a novel therapeutics strategy against liver cancer. , Universiti Sains Malaysia (USM) ( Co-Researcher)
- 2019 - 2022, Fundamental Research Grant Scheme (FRGS)Investigating the role of SIRT1-autophagy regulatory axis in chemoresistance in hepatocellular carcinoma (HCC) using 3D tumour spheroid in vitro model , Sunway University ( Co-Researcher)
- 2013 - 2018, Geran Penyelidikan Universiti Malaya (UMRG)REPROGRAMMING AND PROGRAMMING OF STEM AND SOMATIC CELLS USING EPIGENETIC MODIFIERS. ( Principal Investigator(PI))
International
- 2022 - 2022, International FundingAua-universiti Malaya Overseas Study Program 2021 On Shaping The Future Generation For Life Beyond Covid-19 ( Co-Researcher)
- 2020 - 2022, International FundingSATU Joint Research Scheme (International) Project 1 -Development of Negative Pressure-Platelet Rich Plasma-Based Wound Treatment for Type 2 Diabetes Mellitus ( Principal Investigator(PI))
- 2020 - 2022, International FundingSATU Joint Research Scheme (International) Project 2- Unravel Metabolic-Stemness Plasticity of Cd133+ Liver Cancer Stem Cells Derived from Liver Tumourspheres in Response to Hypoxia ( Principal Investigator(PI))
- 2017 - 2020, International FundingInvestigation on The Role of miRNAs in Ovarian Cancer Progression ( Consultant)
- 2016 - 2018, International FundingA novel bioengineered substrate for human pluripotent stem cell culture ( Consultant)
- 2017 - 2018, International FundingExtracellular vesicles from mesenchymal stem cells as novel approach for cellular rejuvenation. ( Principal Investigator(PI))
- 2015 - 2015, Fludigm CorporationUnraveling heterogeneity of liver cancer stem cells at single cell level. ( Principal Investigator(PI))
University
- 2022 - 2025, University GrantHypoxia-inducible Factors (hifs) Regulatory Axis As Potential Druggable Targets Of Cancer Stem Cell Plasticity In Hepatocellular Carcinoma ( Principal Investigator(PI))
CONSULTANCY PROJECT
- Moa for Research Service With Primanexus Sdn Bhd, Prima Nexus Sdn Bhd, Project Director03 Apr 2019 - 02 Apr 2020 (National)
- Examiner for Phd Thesis and Viva Examination, Project: Immunomodulation- and Angiogenesis-Led Peripheral Nerve Regeneration (Graduate Student: Tzu-Chieh Huang) National Cheng Kung University, Taiwan (International), National Cheng Kung University, Taiwan01 Jan 2020 - 01 Jan 2020 (International)
- Advisor, Tissue Engineering and Regenerative Medicine International Society (Termis)- Asia Pacific Chapter Meeting 2020 Organising Committee (13th Dec 2018- 24th September 2020), TERMIS01 Jan 2018 - 01 Jan 2020 (International)
- External Examiner, Masters of Medical Sciences (Tissue Engineering)- Hanita Binti Mohd Hussin (P86169), UKM, UKM01 Dec 2018 - 01 Dec 2019 (National)
- Reviewer for Travel Award: Tesma-Myceb Travel Grant Award for Termis-Ap 2019, Brisbane, Australia, TERMIS01 Jun 2019 - 01 Jun 2019 (International)
- Examiner, Masters of Clinical Oncology Written and Viva Examination Session 2018/2018, April 2019, Clinical Oncology Unit, University Malaya Medical Centre (Ummc), Clinical Oncology Unit, PPUM01 Jun 2019 - 01 Jun 2019 (National)
- Panel Reviewer for Faculty Research Grant (Frg) and University Malaya Specialist Centre (Umsc) Care Fund Grant, University of Malaya01 Jun 2019 - 01 Jun 2019 (National)
- Panel Reviewer for Fundamental Research Grant Scheme (Frgs) Session 1/2019, University of Malaya01 Jun 2019 - 01 Jun 2019 (National)
- Reviewer: Scientific Reports (Manuscript Id: Srep-18-3946), Title: Extracellular Microenvironmental Change by B16f10 Melanoma-Derived Proteins Induces Cancer Stem-Like Cell Properties from Nih3t3 Cells, Scientific Reports01 Jan 2019 - 01 Jan 2019 (International)
- Reviewer: Manuscript # Mc-18-0555 Entitled "Exosome-Transmitted P120-Catenin Suppresses Hepatocellular Carcinoma Progression Via Stat3 Pathways" for Molecular Carcinogenesis, Molecular Carcinogenesis01 Jan 2019 - 01 Jan 2019 (International)
- Reviewer: Manuscript Bcam-D-19-00508r1, 'Inositol Hexaphosphate Sensitizes Hepatocellular Carcinoma Cells to Oxaliplatin by Inhibiting Abcg1' for Bmc Complementary & Alternative Medicine, BMC Complementary & Alternative Medicine01 Jan 2019 - 01 Jan 2019 (International)
- Reviewer: Manuscript # Sonc-2019-0265 Entitled "Role of Exosomes and Exosomal Micrornas in Cancer" for The Acta Oncologica, Acta Oncologica01 Jan 2019 - 01 Jan 2019 (International)
- Reviewer: Manuscript Mmr-16579-228761, The Molecular Mechanism of Sirt1 Signalling Pathway in Brain Injury of Newborn Rats Exposed to Hyperoxia for Molecular Medicine Reports, Molecular Medicine Reports01 Jan 2019 - 01 Jan 2019 (International)
- Reviewer: Manuscript No: 4824, Titled Generation of Induced Secretome from Adipose-Derived Stem Cells Specialized for Disease-Specific Treatment: An Experimental Mouse Model for World Journal of Gastroenterology, World Journal of Gastroenterology01 Jan 2019 - 01 Jan 2019 (International)
- Reviewer:Revised Manuscript # Mc-18-0555.R1 Entitled "Exosome-Transmitted P120-Catenin Suppresses Hepatocellular Carcinoma Progression Via Stat3 Pathways" for Molecular Carcinogenesis, Molecular Carcinogenesis01 Jan 2019 - 01 Jan 2019 (International)
- Manuscript Reviewer: Cancer Biomarkers Journal, Manuscript 18-2136, Entitled "Suppression of Microrna-141 Suppressed P53 to Protect Against Neural Apoptosis in Epilepsy by Sirt1 Expression (Nov 2018), Cancer Biomarkers01 Dec 2018 - 01 Dec 2018 (International)
- Manuscript Reviewer: Scientific Reports (Manuscript Id: Srep-18-33031) - Therapeutic Effects of a Single Injection of Human Umbilical Mesenchymal Stem Cells On Acute and Chronic Colitis in Mice., Scientific Reports01 Dec 2018 - 01 Dec 2018 (International)
- Book Chapter Reviewer: Book is The Series of Aemb (Advances of Experimental of Medicine and Biology, If:1.887) Published by Springer Nature Pub Co., Springer Nature Pub Co.01 Dec 2018 - 01 Dec 2018 (International)
- Manuscript Reviewer: International Wound Journal: a Full-Term Amniotic Fluid Stem Cells Secreted Secretome Model Accelerates Migration and Proliferation of Diabetic Human Dermal Fibroblast (Feb 2018), International Wound Journal01 Dec 2018 - 01 Dec 2018 (International)
- Examiner, Masters of Clinical Oncology, Clinical Oncology Unit, UM01 Dec 2018 - 01 Dec 2018 (National)
- Examiner, Mmedsc Dissertation for Examination-Koh Sue May (Mgn160014), Department of Orthopaedic Surgery, UM01 Dec 2018 - 01 Dec 2018 (National)
- Manuscript Reviewer: Journal of Natural Agents and Molecular Therapeutics: Strategies to Prevent Recurrence of Colorectal Cancer With Curcumin (January 2018), UM01 Dec 2018 - 01 Dec 2018 (International)
- Manuscript Reviewer: Bioscience Reports (Manuscript Id: Bsr-2018-1980), Title: Exosomal Transfer of Mir124 Inhibits Normal Fibroblasts to Cancer-Associated Fibroblasts Transition in Ovarian Cancer (Nov 2018), Bioscience Reports01 Dec 2018 - 01 Dec 2018 (International)
- Manuscript Reviewer: Manuscript # Sonc-2018-0633 Entitled "The Potential Diagnostic and Prognostic Role of Exosomes in Glioma: Current Status and Future Perspectives" for The Acta Oncologica (October 2018), Acta Oncologica01 Dec 2018 - 01 Dec 2018 (International)
- Panel of Evaluator, Candidature Defence for Phd Student- Sanaz Koosha (Mha 140049), Department of Pharmacology, UM01 Dec 2018 - 01 Dec 2018 (National)
- Jury for International Research Innovation, Invention and Solution Exposition (Iriise), UM01 Dec 2018 - 01 Dec 2018 (International)
- Reviewer, Scientific Report, Manuscript Id Srep-17-27354-T, Scientific Report01 Dec 2017 - 01 Dec 2017 (International)
- Examiner: Doctoral Thesis Examination & Viva Voce - Somayeh Fani (Mha120022)., Department of Pharmacy01 Dec 2017 - 01 Dec 2017 (National)
- Panel of Evaluator : Mmedsc Proposal Defence, Wan Muhammad Farhan Syafiq Bin Wan Mohd Noor, Department of Pharmacy01 Dec 2017 - 01 Dec 2017 (National)
- Reviewer Assignment - Regenerative Research (RR-131216-006 ), Regenerative research01 Dec 2017 - 01 Dec 2017 (International)
- Reviewer, Anti-Cancer Agents in Medicinal Chemistry (Manuscript Id : 1 136), Anti-Cancer Agents in Medicinal Chemistry01 Dec 2017 - 01 Dec 2017 (National)
- Judge: Malaysian Orthopedic Association Moa Conference- Poster Abstract and Presentation, Malaysian Orthopedic Association01 Dec 2017 - 01 Dec 2017 (National)
- Guest Editor: Stem Cell International Special Issue (Autophagy in Stem Cell Biology: a Perspective of Stem Cell Self-Renewal and Differentiation), Hindawi Publishing Corporation01 Dec 2017 - 01 Dec 2017 (National)
- Examiner: Phd Viva Examination (Nam Hui Yin, Department of Orthopedic Surgery), Department of Orthopedic Surgery01 Dec 2017 - 01 Dec 2017 (National)
- Panel of Evaluator, Mmedsc Proposal Defence, Yelena Yeow May Min, Mgn 160039, Department Of Molecular Biology01 Dec 2017 - 01 Dec 2017 (National)
- Reviewer, Current Cancer Drug Targets Journal Manuscript Reference#: Bsp-Ccdt-2, Current Cancer Drug Targets01 Dec 2017 - 01 Dec 2017 (International)
- Internal Examiner: Master of Clinical Oncology Part 1 Examination Session 2016/2017, Clinical Oncology Unit01 Dec 2017 - 01 Dec 2017 (National)
- Reviewer for Allied Academies (Manuscript Id: 17-1687) Title of Manuscript: Clinical Application of Carbon Nanoparticles in Curative Resection for Colorectal Carcinoma: a Report of 470 Cases, Allied Academies01 Dec 2017 - 01 Dec 2017 (National)
- Reviewer, Tissue Engineering and Regenerative Medicine, Manuscript Id Term-D-17-00088, Tissue Engineering and Regenerative Medicine01 Dec 2017 - 01 Dec 2017 (National)
- Reviewer: Tissue Engineering and Regenerative Medicine, Manuscript Id Term-D-17-00088, Tissue Engineering and Regenerative Medicine01 Dec 2017 - 01 Dec 2017 (National)
- Panel of Evaluator, Mmedsc Proposal Defence, Yew Hong Wen, Mgn 160035, , 16 November 2017., Department of Molecular Medicine01 Dec 2017 - 01 Dec 2017 (National)
- Reviewer, Jurnal Teknologi, Manuscript Id 10378, Jurnal Teknologi01 Dec 2017 - 01 Dec 2017 (National)
- Scientific Committee Member, Tissue Engineering and Regenerative Medicine Postgraduate Symposium (Termsympo'2017), Tissue Engineering Centre01 Dec 2017 - 01 Dec 2017 (National)
- Invited Lecture: Writing Literature Review and Review Article (Pg) May 2017, University Malaya01 Dec 2017 - 01 Dec 2017 (National)
- Panel of Judges: Malaysian Orthopedic Association Moa Conference- Poster Abstract and Presentation, Malaysian Orthopedic Association MOA01 Dec 2017 - 01 Dec 2017 (National)
- Reviewer: Anti-Cancer Agents in Medicinal Chemistry, Manuscript Id : 1136, Anti-Cancer Agents in Medicinal Chemistry01 Dec 2017 - 01 Dec 2017 (National)
- Examiner: Viva Voce Examination- Master of Clinical Oncology Part 1, Clnical Oncology Unit01 Dec 2017 - 01 Dec 2017 (National)
- Invited Lecturer: Designing Good Experiments (Pg) May 2017, University Malaya01 Dec 2017 - 01 Dec 2017 (National)
- Examiner: Phd Viva Examination : Naresh Waran, Faculty of Dentistry, UM, Faculty of Dentistry01 Dec 2017 - 01 Dec 2017 (National)
- Panel of Evaluator, Phd Proposal Defence, Ain Zubaidah Ayob, Mha 160036, Department of Molecular Medicine01 Dec 2017 - 01 Dec 2017 (National)
- Examiner: Doctoral Thesis Examination & Viva Voce - Somayeh Fani, Universiti Malaya01 May 2007 - 01 May 2017 (National)
- Examiner:Phd Viva Examination (Candidate- Naresh Waran, Faculty of Dentistry, UM), Faculty of Dentistry01 May 2017 - 01 May 2017 (National)
- Reviewer: Regenerative Research (Manuscript No: RR-180416-006), Regenerative Research01 May 2016 (International)
- Examiner, Phd Thesis and Voce Viva, Naresh Waran Gnanasegaran, Faculty of Dentistry (Oct, 2016), Universiti Malaya01 May 2016 (National)
- Examiner, Phd Thesis and Voce Viva, Nam Hui Yin, Department of Orthopaedic Surgery (Oct, 2016), university of malaya01 Dec 2016 - 01 Dec 2016 (National)
- Panel of Evaluator, Phd Thesis Submission Seminar, Somayeh Fani, Dept of Pharmacy, August 2016, Universiti Malaya01 May 2016 - 01 May 2016 (National)
- Reviewer: Malaysian Journal of Medical Sciences (Manuscript No: RR-180416-006), Malaysian Journal of Medical Sciences01 May 2016 - 01 May 2016 (International)
- Reviewer: World Journal of Gastrointestinal Oncology (Esps Manuscript No: 28864), World Journal of Gastrointestinal Oncology01 May 2016 - 01 May 2016 (International)
- Panel of Evaluator, Phd Candidature Defense, Naresh Waran Gnanasegaran, Faculty of Dentistry, Jan 2016, Universiti Malaya01 May 2016 - 01 May 2016 (National)
- Panel of Evaluator, Final Year Project Biomedical Sciences Programme, Department of Biomedical Science, March 2016, Universiti Malaya01 May 2016 - 01 May 2016 (National)
- Reviewer: Onco-Targets and Therapy (Id: 110281), Onco-targets and Therapy01 May 2016 - 01 May 2016 (International)
- Panel of Evaluator, Mmedsc Candidature Defence, Wen Wei Xiong, Department of Surgery, June 2016., Universiti Malaya01 May 2016 - 01 May 2016 (National)
- Reviewer: World Journal of Gastrointestinal Oncology (Esps Manuscript No: 30540), World Journal of Gastrointestinal Oncology01 May 2016 - 01 May 2016 (International)
- Reviewer: World Journal of Gastroenterology (Esps Manuscript No: 26431), World Journal of Gastroenterology01 May 2016 - 01 May 2016 (International)
- Reviewer: European Journal of Clinical Investigation, Manuscript No: Ejci-2015-0573., European Journal of Clinical Investigation01 May 2016 - 01 May 2016 (International)
- Reviewer: Journal of Hepatocellular Carcinoma (Manuscript Id: 129063), Journal of Hepatocellular Carcinoma01 May 2016 - 01 May 2016 (National)
- Reviewer: Cancer Investigation (Manuscript No: Lcnv-20150336), Cancer Investigation01 May 2016 - 01 May 2016 (International)
- Reviewer: World Journal of Gastroenterology (Esps Manuscript No: 26209), World Journal of Gastroenterology01 May 2016 - 01 May 2016 (International)
- Examiner ,Mmedsc-Phd Conversion Seminar, Kong PO Lian, Department of Pathology, December 2016, Universiti Malaya01 May 2016 - 01 May 2016 (National)
- Examiner, Candidature Defence for Phd Candidate: Somayeh Fani (Dept of Pharmacy), University of Malaya01 Dec 2015 - 01 Dec 2015 (National)
- Examiner, Candidature Defence for Phd Candidate: Nazmul Haque (Dept of Pharmacy), University of Malaya01 Dec 2015 - 01 Dec 2015 (National)
- Examiner, Candidature Defence for Phd Candidate: Fatemah Amadipour (Dept of Pharmacy), University of Malaya01 Dec 2015 - 01 Dec 2015 (National)
- Co-Investigator: Dental Derived Stem Cells for Regenerative Therapies, Prof. Dr. Noor Hayaty Abu Kasim01 Jan 2013 - 01 Jan 2015 (National)
- Regenerative Medicine Masters Programme: Examination Moderation, UCSI University01 Aug 2014 - 01 Aug 2014 (National)
- Research Project Consultancy- Hepatic and Pancreatic Differentiation of Stem Cells, Dr. Shariza Nordin (Clinical Genetics Unit, UPM)01 Jan 2012 - 01 Jan 2014 (National)
PAPER PRESENTED
PLENARY SPEAKER
- Stem Cells in Regenerative Medicine and Cancer, 6th International Conference on Molecular Biology & Biotechnology (ICMBB2023), Malaysian Society for Molecular Biology & Biotechnology (MSMBB) (International) (07 Jun 2023 - 09 Jun 2023)
- Regenerative and Personalized Treatment is the Future of Medicine, International Symposium of Materials on Regenerative Medicine 2020, National Cheng Kung University, Tainan, Taiwan (International) (12 Dec 2020 - 14 Dec 2020)
- An Overview of Regenerative Research in Malaysia, Plenary Speaker at Forum for Cell Therapy and Regenerative Medicine 2019, Title: An Overview of Regenerative Research in Malaysia, 12th August 2019, TMU Center for Cell Therapy and Regeneration Medicine, Taiwan, TMU Center for Cell Therapy and Regeneration Medicine, Taiwan (International) (12 Aug 2019 - 12 Aug 2019)
- Development of stem cell-based and cell-free therapeutics in regenerative medicine, Mechanobiology: Multiscale Biomechanics, Regeneration, Wound Healing, and Pathological Scars symposium, National Cheng Kung University, Tainan, Taiwan (International) (22 Jun 2019 - 22 Jun 2019)
INVITED SEMINAR
- Invited Lecture: Introduction to Central Research Facilities, Postgraduate Research Methodology Course, semester I session 2020/2021, FOM (University) (30 Dec 2020 - 30 Dec 2020)
- Invited Lecture: Cancer Biomarkers, Biomedical Science Programme (MIC3007 Cancer Biology course) , FOM (University) (11 Nov 2020 - 11 Nov 2020)
- Invited Lecture: Cancer Stem Cells, Biomedical Science Programme (MIC3007 Cancer Biology course) , FOM (University) (11 Nov 2020 - 11 Nov 2020)
- Invited Lecture: Planning the Project and Proposal Presentation, Postgraduate Research Methodology Course, semester I session 2020/2021, FOM (University) (14 Oct 2020 - 14 Oct 2020)
- Invited Lecture: Designing Good Experiments, Postgraduate Research Methodology Course, semester I session 2020/2021, FOM (University) (14 Oct 2020 - 14 Oct 2020)
- Invited Lecture: Introduction to Central Research Facilities, Postgraduate Research Methodology Course, semester II session 2019/2020, FOM (University) (11 Mar 2020 - 11 Mar 2020)
- Invited Lecture: Stem Cell Technology and Tissue Engineering, Biomedical Science Programme (MIC4002 course) , FOM (University) (09 Mar 2020 - 09 Mar 2020)
- Invited Lecture: Designing Good Experiments, Postgraduate Research Methodology Course, semester II session 2019/2020, Postgraduate Office of FOM (University) (04 Mar 2020 - 04 Mar 2020)
- Invited Lecture: Designing Good Experiments, Research Methodology, semester I session 2018/2019, Postgraduate Research Methodology Course, FOM (University) (24 Oct 2018 - 24 Oct 2018)
- Invited Lecture: Literature Review and Writing a Review Article, Research Methodology, semester I session 2018/2019, Postgraduate Research Methodology Course, FOM (University) (03 Oct 2018 - 03 Oct 2018)
- Invited Lecture: Introduction to Central Research Facilities, Research Methodology, semester I session 2018/2019, Postgraduate Research Methodology Course, FOM (University) (19 Sep 2018 - 19 Sep 2018)
- Invited Lecture: Designing Good Experiments, Research Methodology, semester II session 2017/2018, Postgraduate Research Methodology Course, FOM (University) (07 Mar 2018 - 07 Mar 2018)
- Invited Lecture: Literature Review and Writing a Review Article, Research Methodology, semester II session 2017/2018, Postgraduate Research Methodology Course, FOM (University) (28 Feb 2018 - 28 Feb 2018)
- Invited Lecture: Introduction to Central Research Facilities, Research Methodology, semester II session 2017/2018, Postgraduate Research Methodology Course, FOM (University) (07 Feb 2018 - 07 Feb 2018)
INVITED SPEAKER
- Empowering innovation through AUA-Overseas study program, UM Health Academia Month & Research Carnival 2023, Faculty of Medicine, UM (University) (02 Oct 2023 - 06 Oct 2023)
- Stem Cells in Disease Modelling, Drug Discovery and Therapeutic Development, 2023 International Symposium of Materials in Regenerative Medicine (ISOMRM), 2023 ISOMRM & BCRS Organization Committee (International) (31 Aug 2023 - 03 Sep 2023)
- Targeting Cancer Stem Cells Opportunities & Therapeutic Paradigm, International Meeting - 47th Annual Conference of The Malaysian Society for Biochemistry and Molecular Biology (IM-MSBMB47), The Malaysian Society for Biochemistry and Molecular Biology (International) (23 Aug 2023 - 24 Aug 2023)
- SATU Project Sharing- Development of Negative Pressure-Platelet Rich Plasma-Based Wound Treatment for Type 2 Diabetes Mellitus, Virtual Meeting between National Cheng Kung University and Universiti Malaya Medical Schools, Universiti Malaya & National Cheng Kung University (International) (14 Dec 2020 - 14 Dec 2020)
- Invited Lecture: Planning the Project and Proposal Presentation, Postgraduate Research Methodology Course, semester II session 2019/2020, FOM (University) (19 Feb 2020 - 19 Feb 2021)
- Manuscript Writing Workshop, Invited Expert for Manuscript Writing Workshop, hands-on 1-to-1 consultation session for 6 postgraduate students, 30th July 2019, Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Taiwan, Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Taiwan (International) (30 Jul 2019 - 30 Jul 2019)
- So are you ready with your scientific story? The art of manuscript writing, Invited speaker, Title: So are you ready with your scientific story? The art of manuscript writing,30th July 2019, College of Medicine, National Cheng Kung University, Taiwan, College of Medicine, National Cheng Kung University, Taiwan (International) (30 Jul 2019 - 30 Jul 2019)
- Multiple Signalling Pathways Regulating Definitive Endoderm Differentiation from Human Embryonic Stem Cells, International Wound Repair and Regeneration Center Seminar, National Cheng Kung University, Taiwan (International) (18 Jun 2019 - 18 Jun 2019)
- Multiple Signalling Pathways Regulating Definitive Endoderm Differentiation from Human Embryonic Stem Cells, Invited speaker at International Wound Repair and Regeneration Center: talk on Multiple Signalling Pathways Regulating Definitive Endoderm Differentiation from Human Embryonic Stem Cells , 18th June 2019, National Cheng Kung University, Taiwan (international), National Cheng Kung University, Taiwan (International) (18 Jun 2019 - 18 Jun 2019)
- DEVELOPMENT OF STEM CELL-BASED THERAPEUTIC STRATEGIES FOR REGENERATIVE MEDICINE, , THE 7th INTERNATIONAL CONFERENCE ON BIOTECHNOLOGY FOR THE WELLNESS INDUSTRY, UTM (International) (27 Nov 2018 - 28 Nov 2018)
- Integrated Workflow of Central Research Facility , Science Cafe: FOM Central Research Facilities & Services Series, Faculty of Medicine, University of Malaya (University) (30 Jul 2018 - 30 Jul 2018)
- 3D cell culture system as a tool for regenerative medicine, disease modelling and drug discovery applications, 3rd Asian University Symposium For Biomedical Engineering, Kyung Hee University, Seoul, South Korea (International) (05 Jul 2018 - 07 Jul 2018)
- Tissue Engineering and Regenerative Research in Malaysia, 6th UTAR Seminar on Stem Cell and iPSC Research (6thUTAR SCiP) 2018, UTAR  (National) (26 Jun 2018 - 26 Jun 2018)
- An Overview of Stem Cell and Regenerative Research in Malaysia, PGM-TESMA Seminar: Tailoring Towards Applications of Genetics in Regenerative Medicine, UPM, PGM & TESMA (National) (28 Mar 2018 - 28 Mar 2018)
- Introduction to Central Research Facilities, Postgraduate Research Methodology Course, Dean's Office (University) (13 Dec 2017 - 13 Dec 2017)
- Designing good experiments, Postgraduate Research Methodology Course, Dean's Office, FOM (University) (06 Dec 2017 - 06 Dec 2017)
- Writing a review article : 10 simple rules, Postgraduate Research Methodology Course, Dean's Office, FOM (University) (29 Nov 2017 - 29 Nov 2017)
- An Overview of Regenerative Research in Malaysia, Tissue Engineering and Regenerative Medicine Society of Malaysia (TESMA) Seminar Series 2017, Tissue Engineering and Regenerative Medicine Society of Malaysia (TESMA)  (National) (22 Nov 2017 - 22 Dec 2017)
- Unravel Hidden Tale Of Cancer Stem Cells: Molecular And Cellular Osccilations Through Single Cell Biology, 7th Annual Next Generation Sequencing & Clinical Diagnostics Asia Congress, 5th Annual Single Cell Analysis AsiaCongress and 4th Annual Microbiology & Infectious Diseases Asia Congress, Oxford Global (International) (10 Oct 2017 - 11 Oct 2017)
- Designing good experiments, Postgraduate Research Methodology Course, Dean's Office, FOM (University) (03 May 2017 - 03 May 2017)
- Writing a review article : 10 simple rules, Postgraduate Research Methodology Course, Dean's Office (University) (26 Apr 2017 - 26 Apr 2017)
- Introduction to Central Research Facilities, Postgraduate Research Methodology Course, Dean's Office (University) (22 Feb 2017 - 22 Dec 2017)
- Designing good experiments, Postgraduate Research Methodology Course, Dean's Office, FOM (University) (30 Nov 2016 - 30 Nov 2016)
- Writing a review article : 10 simple rules, Postgraduate Research Methodology Course, Dean's Office, FOM (University) (23 Nov 2016 - 23 Nov 2016)
- Cutting Edge Research: Cell and Molecular Biology & Role of Central Research Laboratories (CRL), Faculty of Medicine, Central Research Laboratories' Open Day 2016, Central Research Laboratories (CRL) (University) (03 Nov 2016 - 03 Nov 2016)
- Introduction to Central Research Facilities, Faculty of Medicine, Postgraduate Research Methodology Course, the Dean's Office, FOM (University) (21 Sep 2016 - 21 Sep 2016)
- Regenerative Medicine : from bench to bedside and back again, International Conferences of Regenerative Medicine: Bench to Bedside Applications, Asean Regenerative Medicine Society, Thai Medical Association, Bangkok, Thailand (International) (08 Jul 2016 - 08 Jul 2016)
- Harnessing the Therapeutic Potential of Multipotent Stem Cells: Progress & Challenges, Malaysia Association for Cell Therapy Annual Symposium 2016, Malaysia Association for Cell Therapy (National) (02 Apr 2016 - 02 Apr 2016)
- Mesenchymal Stem Cells & Platelet Rich Plasma: Cellular & Acellular Approaches in Regenerative Medicine, Regenerative Medicine: Bench to Bedside Applications, Asean Institute of Integrative Medicine, Bangkok, Thailand (International) (22 Feb 2016 - 22 Feb 2016)
- Targeting Cancer Stem Cells: an Insight into Therapeutic Mechanisms, International Conference of Herbal & Synthetic Drug Studies 2016, Interdisciplinary Science and Technology Research Academy, India (International) (07 Jan 2016 - 09 Jan 2016)
- First steps towards personalized cell -replacement therapy for liver diseases: from human pluripotent stem cells into functional hepatocytes , 4th UTAR Seminar on Stem Cell and iPSC Research , Centre for Stem Cell Research (CSCR), UTAR (National) (03 Aug 2015 - 04 Aug 2015)
- Epigenetics meets orthopeadics, 45th Malaysian Orthopaedic Association Annual Scientific Meeting 2015, Malaysian Orthopaedic Association (International) (22 May 2015 - 24 Jun 2015)
- Central Research Facility FOM, Research Methodology Course, Faculty of Medicine (University) (10 Feb 2015 - 10 Feb 2015)
- Mesenchymal Stromal Cells: A Perspective from in vitro cultures to clinics, Mesenchymal Stromal Stem Cells and its Clinical Application Workshop, NOCERAL, UM (National) (29 Jan 2015 - 31 Jan 2015)
- Introduction to Stem Cells and Regenerative Medicine, Mesenchymal Stromal Stem Cells and its Clinical Application Workshop, NOCERAL, UM (National) (29 Jan 2015 - 30 Jan 2015)
- Introduction to Research Methodology/Central Facilities/Grant Application, Research Methodology for Postgraduate Research Course, Faculty of Medicine (17 Sep 2014 - 17 Sep 2015)
- Towards Personalised Cell Therapy: Human Pluripotent Stem Cell as Research & Therapeutic Tool for Liver Diseases , The 5th Malaysian Tissue Engineering and Regenerative Medicine Scientific Meeting, TESMA (National) (17 Sep 2014 - 19 Sep 2014)
- Introduction to Research Methodology/Central Facilities/Grant Application , Research Methodology for Postgraduate Research Course , Faculty of Medicine (University) (19 Feb 2014 - 19 Feb 2015)
- Multiple Signalling Pathways Regulating Definitive Endoderm Differentiation from Human Embryonic Stem Cells , 3rd UTAR Seminar on Stem Cell and iPSC Research: Basic and Translational Aspect, UTAR Centre for Stem Cell Research (National) (02 Dec 2013 - 02 Dec 2013)
- Engineering cell fate: from human embryonic stem cells to functional hepatocytes, TESMA SEMINAR SERIES APRIL 2013, Tissue Engineering & Regenerative Medicine Society of Malaysia (TESMA) and Faculty of Medicine & Health Sciences, UPM. (National) (30 Apr 2013 - 30 Apr 2013)
EVENT ORGANISER
- Moderator, Immunology and Microbiota, Universiti Malaya-Chang Gung Memorial Hospital (UM-CGMH) Webinar series, UM-CGMH (International) (21 Dec 2020 - 21 Dec 2020)
- Moderator, Lecture 3: Quantifying cellular ATP production rate and XFnormalisation solutions, Real-time cell metabolic analysis webinar series, CMBL in collaboration with Research Instruments (International) (18 Dec 2020 - 18 Dec 2020)
- Moderator, From Big Data to Precision Medicine, Science Caf , FOM Research Office (National) (26 Nov 2020 - 26 Nov 2020)
- Moderator, Lecture 1: Bringing Metabolic Pathways to Live, Real-time cell metabolic analysis webinar series, CMBL in collaboration with Research Instruments Sdn Bhd (International) (20 Nov 2020 - 20 Nov 2020)
- Chair of organising committee & moderator,, Seminar: Maintenance of Autoclave & Biological Indicator, Cell & Molecular Biology Laboratory, Faculty of Medicine, University of Malaya, in collaboration with FC-Bios Sdn. Bhd (National) (10 Nov 2020 - 10 Nov 2020)
- Moderator, Atomic Force Microscopy for Cell and Biomaterial Applications, TESMA webinar series 2020, TESMA (National) (17 Jun 2020 - 17 Jun 2020)
- Chair of Organising Committee & Consultant , Workshop: Basic Cell Culture Workshop, 29/4/2019, Cell & Molecular Biology Laboratory (CMBL), Faculty of Medicine, University of Malaya, in collaboration with SPD Scientific Sdn Bhd., Cell & Molecular Biology Laboratory (National) (29 Apr 2020 - 30 Apr 2019)
- Consultant & Chair of the organising committee, Basic Cell Culture Workshop, Cell & Molecular Biology Laboratory (CMBL), Faculty of Medicine, University of Malaya, in collaboration with SPD Scientific Sdn Bhd. (National) (National) (05 Mar 2020 - 05 Mar 2020)
- Moderator, Seminar: Microenvironmental and Biochemical Cues for Stem Cells in PNS regeneration, Science Cafe, FOM (National) (04 Feb 2020 - 04 Feb 2020)
- Consultant & Chair of the organising committee, Basic Cell Culture Workshop , Cell & Molecular Biology Laboratory (CMBL), Faculty of Medicine, University of Malaya, in collaboration with SPD Scientific Sdn Bhd.  (National) (22 Jan 2020 - 22 Jan 2020)
- Consultant & Chair of Organising Commitee, Basic Cell Culture Workshop, Cell & Molecular Biology Laboratory (CMBL), Faculty of Medicine, University of Malaya, in collaboration with SPD Scientific Sdn Bhd.  (National) (21 Jan 2020 - 21 Jan 2020)
- Chair of Organising Committee, Next-Generation Image-to-3D Model & 3D Bio-Printing Technologies,23/7/2019, Medical Biotechnology Laboratory (MBL), in collaboration with Dazztech Solution Sdn. Bhd., , Cell & Molecular Biology Laboratory (National) (23 Jul 2019 - 23 Jul 2019)
- Chair of Organising Committee, Seminar: Real Talk: Be a Smart Autoclave User, 4/7/2019, The CUBE, Faculty of Medicine, University of Malaya, in collaboration with FC-Bios Sdn. Bhd., Cell & Molecular Biology Laboratory  (National) (04 Jul 2019 - 04 Jul 2019)
- Chair of Organising Committee, Workshop: Live Cell Metabolism Bioassay Hands-on Workshop,26/2/2019, Cell & Molecular Biology Laboratory (CMBL), Faculty of Medicine, University of Malaya, in collaboration with Research Instruments Sdn. Bhd., , Cell & Molecular Biology Laboratory  (National) (26 Feb 2019 - 26 Feb 2019)
- Facilitator, , UMMP Problem-based Learning Training Workshop, MERDU, FOM (University) (30 Nov 2018 - 14 Dec 2018)
- Chair of organising committee, University of Malaya -Taipei Medical University Research Collaboration Meeting, UM (University) (19 Oct 2018 - 19 Oct 2018)
- Chair of Organising Committee, Stem Cell & Cancer Symposium 2018, FOM (National) (17 Oct 2018 - 18 Oct 2018)
- Chair of Programme & Hons Secretary, Innovation Forum Kuala Lumpur 2018 (University), University of Malaya (National) (22 Sep 2018 - 22 Sep 2018)
- Workshop Coordinator, Towards Innovative Regenerative Medicine , Innovation Forum Kuala Lumpur 2018 (University), University of Malaya (National) (21 Sep 2018 - 21 Dec 2018)
- Seminar, Downstream Application of Cell Culture Seminar, 2018-09-19, University of Malaya, CMBL partnership with PLT Scientific Sdn. Bhd. , CMBL (University) (19 Sep 2018 - 19 Sep 2018)
- Deputy Chair of organising committee, The 17th International Conference of the Asia Pacific Association of Surgical Tissue Banks (APASTB2018), MACTB, TESMA & MBS (International) (28 Aug 2018 - 30 Aug 2018)
- Moderator, The 17th International Conference of the Asia Pacific Association of Surgical Tissue Banks (APASTB2018) (28-30th August 2018) (International), MACTB, TESMA & MBS (International) (28 Aug 2018 - 30 Aug 2018)
- Seminar, Cell Maintainance & Handling seminar, CMBL partnership with Bio Focus Sdn. Bhd. , CMBL (University) (02 Aug 2018 - 02 Aug 2018)
- Seminar, Discover the power of real time: Live cell metabolism analysis, CMBL partnership with Research Instruments Sdn. Bhd., CMBL (University) (28 Jun 2018 - 28 Jun 2018)
- Workshop, Cell Culture & MTT Assay Workshop, The CUBE, Faculty of Medicine, CMBL partnership with Prima Nexus Sdn. Bhd., CMBL (National) (24 Apr 2018 - 26 Apr 2018)
- Seminar, Discover the Power of Clariom Assays (Microarray Introductory Seminar), CMBL partnership with Research Instruments Sdn. Bhd. , CMBL (University) (30 Mar 2018 - 30 Mar 2018)
- Advisor, , PGM-TESMA Seminar: Tailoring towards the application of genetics in regenerative medicine, PGM-TESMA (National) (28 Mar 2018 - 28 Mar 2018)
- Workshop,, ELISA Hands-On Workshop, CMBL partnership with Prima Nexus Sdn. Bhd. , CMBL (National) (20 Mar 2018 - 20 Mar 2018)
- Seminar, Multiplex- Simplified Complexity, University of Malaya partnership with Prima Nexus Sdn. Bhd. , CMBL (University) (02 Mar 2018 - 02 Mar 2018)
- Chair, Urinary Tract Wound Healing, With a Specific Focus on The Urothelium, CMBL (University) (27 Feb 2018 - 27 Feb 2018)
- Seminar, Good Laboratory Pipetting Practices and Cell Culture Seminar, 2018-02-26, University of Malaya partnership with Fisher Scientific (M) Sdn. Bhd. , CMBL (University) (26 Feb 2018 - 26 Feb 2018)
- Chair of Organising Committee: , Workshop- Explore The RNA with Real-Time PCR Using Gene Expression Profiler, 20-21/2/2019, The CUBE, Faculty of Medicine, University of Malaya, Qiagen Biotechnology Malaysia Sdn. Bhd., National, Cell and Molecular Biology Laboratory  (National) (20 Feb 2018 - 21 Feb 2019)
- Basic Cell Culture Training, Basic Cell Culture Training, CMBL (University) (15 Dec 2017 - 15 Dec 2017)
- Seminar on Balancing Act PCR Optimisation, Seminar on Balancing Act PCR Optimisation, CMBL (University) (02 Nov 2017 - 02 Nov 2017)
- Seminar on Innovative Strategies for Stem Cell Research, Seminar on Innovative Strategies for Stem Cell Research, Cell & Molecular Biology Laboratory (CMBL) partnership with Bio-Diagnostics Sdn Bhd (University) (29 May 2017 - 29 May 2017)
- Stem Cell Lab Tour MBEB3105, Application of Stem Cell and Tissue Engineering, Stem Cell Lab Tour MBEB3105, Application of Stem Cell and Tissue Engineering, Biology Stem Cell Laboratory (University) (26 May 2017 - 26 May 2017)
- Electric Cell-Substrate Impedance Sensing (ECIS) System Seminar & Workshop, Electric Cell-Substrate Impedance Sensing (ECIS) System Seminar & Workshop, Cell & Molecular Biology Laboratory (CMBL) partnership with Chimera-Tech Sdn Bhd and Precision Technologies Pte Ltd (University) (22 May 2017 - 23 May 2017)
- Seminar on Starting Your Journey With Cell Culture System, Seminar on Starting Your Journey With Cell Culture System, Cell & Molecular Biology Laboratory (CMBL) partnership with Bio-Diagnostics Sdn Bhd.  (University) (18 May 2017 - 18 May 2017)
- Western Blot Hands-On Workshop, Western Blot Hands-On Workshop, Molecular Biology Laboratory (CMBL) partnership with Biomarketing Services (M) Sdn Bhd. (University) (27 Apr 2017 - 27 Apr 2017)
- Biosafety Awareness Seminar, Biosafety Awareness Seminar, Molecular Biology Laboratory (CMBL) partnership with ESCO. (University) (14 Apr 2017 - 14 Apr 2017)
- ELISA Hands-On Workshop, ELISA Hands-On Workshop, Medical Biotechnology Laboratory ( MBL) partnership with Prima Nexus Sdn. Bhd. (University) (05 Apr 2017 - 05 Apr 2017)
- Chair of Organising Commitee, Central Research Laboratories' Open Day 2016, Central Research Laboratories (CRL) (University) (03 Nov 2016 - 03 Nov 2016)
- Cellular Analysis: Viability, Proliferation and Function, Cell Analysis Roadshow 2016, Cell & Molecular Biology Laboratory (CMBL)  (University) (24 Feb 2016 - 24 Feb 2016)
- Overview of Cancer Stem Cells, TESMA/CMBL Seminar Series 2015 : Cancer Stem Cells , CMBL & TESMA (University) (19 Nov 2015 - 19 Nov 2015)
- Co-chair, 5th Malaysia Tissue Engineering & Regenerative Medicine Scientific Meeting 2014, Tissue Engineering and Regenerative Medicine Society of Malaysia (National) (17 Sep 2014 - 19 Sep 2014)
- Chair of organizing committee, Tissue Engineering and Regenerative Medicine Society of Malaysia (TESMA)Seminar Series 2014, Medical Biotechnology Laboratory jointly organized with Tissue Engineering and Regenerative Medicine Society of Malaysia  (National) (06 Jan 2014 - 06 Jan 2014)
- Organiser, Biotech Open Day 2013, Medical Biotechnology Laboratory (University) (13 Nov 2013 - 13 Nov 2013)
ORAL PRESENTER
- Hepatic differentiation of human embryonic stem cells: In vitro strategies, Engineering Cell Fates Conference (Biopolis, Singapore), Abcam (International) (28 May 2013 - 28 May 2013)
POSTER PRESENTER
- MiR-302/ MiR-22 Switch is Associated with in Vitro Aging of Human Mesenchymal Stem Cells, Keystone Symposia Conference 15-19 October 2017, Keystone Symposia  (University) (15 Dec 2017 - 19 Dec 2017)
- Student under supervision: Ain Zubaidah Ayob. Effects of hypoxia on the induction of cancer stem cells-like properties in tumourspheres derived from HepG2 cells, Tissue Engineering and Regenerative Medicine Postgraduate Symposium (TERMSYMPO) 2017, Tissue Engineering and Regenerative Medicine  (National) (07 Nov 2017 - 07 Nov 2017)
- Student under supervision: Yew Hong Wen. Association of Proliferation and Cell Cycle Status in Determination of Mesenchymal Stem Cells Fate, Keystone Symposia Conference, Keystone Symposia (International) (15 Oct 2017 - 19 Oct 2017)
- MicroRNA analysis of Human Mesenchymal Stem Cells during in vitro aging, The 5th Malaysian Tissue Engineering & Regenerative Medicine Scientific Meeting (MTERMS), Tissue Engineering & Regenerative Medicine Society of Malaysia (TESMA) (National) (17 Nov 2016 - 18 Nov 2016)
- Enrichment of hepatic cancer stem cells in different in vitro culture systems exhibiting distinct molecular and cellular characteristics recapitulate tumour heterogeneity, The 5th Malaysian Tissue Engineering & Regenerative Medicine Scientific Meeting (MTERMS), Tissue Engineering & Regenerative Medicine Society of Malaysia (TESMA) (National) (17 Nov 2016 - 18 Nov 2016)
- Quiescent Cancer Stem Cells: The Silent Killer?, Central Research Laboratories (CRL) Open Day 2016, Central Research Laboratories (CRL) (University) (03 Nov 2016 - 03 Nov 2016)
- THE DRIVERS OF STEM CELL AGING: HOW MUCH DO WE KNOW?, Central Research Laboratories (CRL) Open Day 2016, Central Research Laboratories (CRL) (University) (03 Nov 2016 - 03 Nov 2016)
- THE ROLE OF CELL CYCLE IN REGULATING STEM CELL FATE, Central Research Laboratories (CRL) Open Day 2016, Central Research Laboratories (CRL) (University) (03 Nov 2016 - 03 Nov 2016)
- How do cancer stem cells contribute to tumour heterogeneity?, Central Research Laboratories (CRL) Open Day 2016, Central Research Laboratories (CRL) (University) (03 Nov 2016 - 03 Nov 2016)
- Release of hair growth regulatory factors by hair follicle stem cells when cultured in four different culture media: a preliminary study, The 9th world Congress for Hair Research, North American Hair Research Society (International) (18 Nov 2015 - 21 Nov 2015)
- Effect of Bacterial LPS at Various Concentrations on Proliferation and Inflammation Induction in DPSC: An In Vitro Model., The 2015 Tissue Engineering Congress (International) (08 Sep 2015 - 10 Sep 2015)
- Modulation Of Signaling Pathways And 3d Culture Enhance Hepatic Differentiation From Human Embryonic Stem Cells: A Comprehensive Culture System Recapitulating In Vivo Liver Development, The 5th Malaysian Tissue Engineering and Regenerative Medicine Scientific Meeting (National) (17 Sep 2014 - 19 Sep 2014)
- 3D Culture Improves Hepatocyte Differentiation of Human Embryonic Stem Cell-Derived Definitive Endoderm Cells, 1st National Stem Cell Congress (Kuala Lumpur, Malaysia), Ministry of Health & UKM Medical Molecular Biology Institute, Malaysia (National) (29 Oct 2012 - 30 Oct 2012)
- Suppression of PI3K/Akt signalling enhances Activin- induced definitive endoderm and hepatocyte differentiation of human embryonic stem cells, UKNSCN's 4th Annual Stem Cell Conference (York, UK), UK National Stem Cell Network (International) (30 Mar 2011 - 01 Apr 2011)
- Inhibition of phosphatidylinositol-3-kinase signalling promotes Activin A induced definitive endoderm differentiation of human embryonic stem cells., The 16th International Conference of the International Society of Differentiation: From Stem Cell to Organisms (Nara, Japan), International Society of Differentiation (International) (15 Nov 2010 - 18 Nov 2010)
PRESENTER
- Therapeutic Potential of Stem Cells: From Experiment to Clinic, Molecular Medicine Research Day, Department of Molecular Medicine (University) (31 May 2016 - 31 May 2016)
KEYNOTE SPEAKER
- Current Updates on Regnerative Medicine, Cellular & Gene Therapy (CGT) in Malaysia, 2023 Forum for Cell Therapy and Regenerative Medicine, Research Center for Cell Tehrapy and Regenerative Medicine, Taipei Medical Universitiy (International) (06 Sep 2023 - 06 Sep 2023)
OTHERS
- Towards the Development of a User-Centred Health Management Application for Elderly , 2nd International Conference on Advancements in Computing (ICAC) 2020, Faculty of Computing of Sri Lanka Institute of Information Technology (SLIIT)  (International) (10 Dec 2020 - 11 Dec 2020)
- Moderator, Lecture 2: Measuring mitochondria and energy pathways in live cells, Real-time cell metabolic analysis webinar series, CMBL in collaboration with Research Instruments Sdn Bhd (International) (04 Dec 2020 - 04 Dec 2020)
ACADEMIC/PROF. SERVICES
Evaluation
- (2023) Fulbright U.S. Student Program, International, (External Assessor)
- (2020) Reviewer, World Journal of Stem Cells Manuscript NO: 55168, March 2020, (Reviewer)
- (2020) Reviewer, manuscript BMS-CSCRT-2020-106 for Current Stem Cell Research & Therapy, Title: Evaluation of differentiation quality of several differentiation inducers of bone marrow-derived mesenchymal stem cells to nerve cells by assessing expression of beta-tubulin 3 marker: a systematic review, Oct 2020 (International), (Reviewer)
- (2020) Reviewer, manuscript BMS-CSCRT-2020-141 for Current Stem Cell Research & Therapy. Title: How Similar Are Human Mesenchymal Stem Cells Derived From Different Origins? A Review of Comparative Studies (International), (Reviewer)
- (2020) Reviewer, manuscript FON-2020-0846 entitled "A BIRC3-driven Therapeutic Strategy for Resectable Esophageal Cancer: the randomized phase II BoRgES trial design" for Future Oncology, Aug 2020 (International)v, (Reviewer)
- (2020) Reviewer, manuscript MOLE-D-20-01155 for Molecular Biology Reports, Apr 2020, (Reviewer)
- (2020) Reviewer, manuscript MOLN-D-20-00939 for Molecular Neurobiology, title: Stem cells derived exosomes: A new strategy of neurodegenerative disease treatment, Oct 2020 (International), (Reviewer)
- (2020) Reviewer, Manuscript Ms. No. TERM-D-20-00146, titled: Mannitol augments the effects of systemical stem cell transplantation without increasing cell migration in a stroke animal model, Tissue Engineering and Regenerative Medicine, July 2020 (International), (Reviewer)
- (2020) Reviewer, Manuscript Ms. Ref. No.: LFS-D-20-02044R1, Title: Estradiol modulated colorectal cancer stem cells bioactivity and interaction with endothelial cells for journal Life Sciences, June 2020, (Reviewer)
- (2020) Reviewer, manuscript submitted to BIOCELL, Title: The gastric cancer stem-like cells could create an immunosuppressive tumor microenvironment ex vivo, November 2020 (International), (Reviewer)
- (2020) Reviewer, Manuscript submitted to Biochemical Genetics, Title: Transcriptome profiling of cancer stem cells reveals seed genes of tumorigenesis, Nov 2020 (International), (Reviewer)
- (2020) Reviewer, Manuscript Title: Contribution of CYP3A4*18 and CYP3A5*3 Polymorphisms in Modulating Susceptibility Risk In Malaysian Chronic Myeloid Leukemia Patients, manuscript Reference Number: 2020/AOS/411 for Archives of Orofacial Sciences (AOS), (Reviewer)
- (2020) Reviewer, Title: Exosomal miR-182, miR-301a, and miR-373 as potential biomarker in NASH-induced liver cirrhosis with hepatocellular carcinoma, for Malaysian Journal of Pathology, June 2020 (International), (Reviewer)
- (2020) Reviewer, World Journal of Clinical Oncology Manuscript NO: 54952., March 2020, (Reviewer)
- (2020) Reviewer, book proposal submitted to springer publisher, Title: Cancer Stem Cells: The bad seeds for Cancer, November 2020 (International), (Reviewer)
- (2020) Reviewer, manuscript # JCMM-05-2020-167 entitled "SIRT1-mediated deacetylation of p53 is implicated in human colorectal cancer progression and chemoresistance by miR-101/KPNA3" for the Journal of Cellular and Molecular Medicine, June 2020, (Reviewer)
- (2020) Reviewer, manuscript # JCP-20-3884 entitled "The role of mesenchymal stem cells in the induction of cancer-stem cell phenotype" for the Journal of Cellular Physiology, Oct 2020 (International), (Reviewer)
- (2020) Reviewer, manuscript # TCRT-20-1097 entitled "MiR-205-3p promotes lung cancer progression through targeting APBB2" for Technology in Cancer Research & Treatment, Oct 2020 (International), (Reviewer)
- (2015) Examiner, Candidature Defence Nam Hui Yin, Dept of Orthopeadic Surgery (23 June 2014), (Internal Examiner)
- (2015) Internal examiner for Doctoral (PhD) Thesis and Viva Voce Examination: Yeannie Yap Hui Heng (MHA110016), PhD examination, April 2015, (Internal Examiner)
- (2014) The effects of uniaxial cyclic tensile loading on human bone Marrow-derived mesenchymal stromal cells in vitro., (Internal Examiner)
- (2014) Research proposal for PhD and MDSc candidates : Dr. Priya and Bashira, (Examiner)
- (2013) Examiner for PhD Thesis and Viva Voce: Tan Sik Loo (MHA080017) , (Internal Examiner)
- (2013) Examiner for Candidature Defence of Master of Medical Science student: Tay Liang Xin (MGN 10023) , (Internal Examiner)
- (2013) Examiner for Candidature Defence of Master of Medical Science student: Krishnamurity Ganesan (MGN 090015) , (Internal Examiner)
- (2013) Examiner for Candidature Defence of Master of Medical Science student: Wee Ai Sze (MGN 090014) , (Internal Examiner)
- (2013) Examiner for Candidature Defence of PhD student: Chong Pan Pann (MHA 0600006) , (Internal Examiner)
- (2013) External Examiner, Project Papers- 16 Masters candidates, Masters in Regenerative Medicine UCSI University , (External Examiner)
- (2012) Reviewer of manuscript (ID:NASB-D-12-00122)Proceedings of the National Academy of Sciences, Biological Sciences (NASB) , (Reviewer)
- (2012) Examiner for Candidature Defence of PhD student: Ursula Chong Rho Wan (MHA 100025) , (Internal Examiner)
Contribution to external organisation
- (2023) Mrun Research Officer Grant Scheme (Mrogs), National, (Resource Person)
- (2023) Young Leaders Alumni Meeting, International, (Resource Person)
- (2023) Tissue Engineering and Regenerative Medicine International Society-Asia Pacific (Termis-Ap)-Abstract Reviewing Panel of The 2023 Termis-Ap Conference, International, (Resource Person)
- (2023) Moa With Cancer Research Malaysia for Laboratory Services, National, (Resource Person)
- (2021) Moa With Spd Scientific Sdn Bhd for Research Training, National, (Resource Person)
- (2021) Moa With Prima Nexus Sdn Bhd for Research Services, National, (Resource Person)
- (2021) Moa With Cancer Research Malaysia for Laboratory Services, National, (Resource Person)
- (2021) Moa With Research Instrument Sdn Bhd for Research Services, National, (Resource Person)
- (2020) Moa With Primanexus Sdn Bhd for Research Services, National, (Resource Person)
- (2020) Dr. Nurulisa Zulkifle, Advanced Medical and Dental Institute (AMDI), USM, 3.FRGS Project: Understanding the molecular regulation of Sirtuinl-p53 axis in hypoxic HepG2 for the development of a novel therapeutics strategy against liver cancer , USM, National
- (2020) MOA-Industrial collaboration & laboratory service: CMBL-Primanexus Sdn Bhd: ELISA and Multiplex Immunoassay Service , Primanexus Sdn Bhd, National
- (2020) MOA-Industrial collaboration & laboratory service: CMBL-Research Instruments Sdn Bhd Live-cell metabolism assay platform, Research Instruments Sdn Bhd, National
- (2020) MOA-Industrial collaboration & laboratory service: CMBL-SPD Scientific Sdn Bhd for Cell Culture Workshop/Training Module, SPD Scientific Sdn Bhd, National
- (2020) MOA-Industrial collaboration & tenancy: CMBL-Cancer Research Malaysia (CRM) tenancy agreement, Cancer Research Malaysia , National
- (2020) Dr Teow Sin Yeang, School of Healthcare and Medical Sciences, Sunway University, 4.FRGS Project: Investigating the role of SIRT1-autophagy regulatory axis in chemoresistance in hepatocellular carcinoma (HCC) using 3D tumour spheroid in vitro model, Sunway University, National
- (2019) Research collaboration, Prof. Dr. Chia Ching Wu, National Cheng Kung University, Taiwan. Project: role of epigenetic in peripheral neuro-regeneration, National Cheng Kung University, International
- (2018) Nichi-Asia Life Sciences Sdn Bhd, Project Collaboration, Nichi-Asia Life Sciences Sdn Bhd, National
- (2018) Cryocord Sdn Bhd, Project collaboration, Cryocord Sdn Bhd, National
- (2018) Dr. Darius Widera (University of Reading, United Kingdom), Collaboration in scientific writing, University of Reading, UK, International
- (2018) Dr. Lee Sau Har (Taylor s University, Malaysia), collaboration in scientific writing, Taylor s University, Malaysia, National
- (2018) Prof. Dr. Shrikant Anant (Kansas University Medical Centre, Kansas, USA) Collaboration in scientific writing, Kansas University Medical Centre, Kansas, US, International
- (2018) Prof. Dr. Patricia Murray (University of Liverpool, United Kingdom), Research Leave, Project collaboration, University of Liverpool, UK, International
- (2012) Organising Committee - 3-minute thesis competition, Faculty of Medicine
SUPERVISION
Postgraduate Student
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(2024) effects of resveratrol loaded nanoparticles against lung cancer:in vitro and in vivo studies, ALISA RAIHANA BINTI SAIFUL HAKIM
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(2024) INVESTIGATION OF THE ROLES OF SPOCK1 IN THE INTERPLAY BETWEEN EPITHELIAL-MESENCHYMAL TRANSITION AND CANCER STEM CELL PLASTICITY IN HEPATOCELLULAR CARCINOMA CELL LINES, RACHEL HOE HUEY XUAN
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(2024) INVESTIGATION OF PI3K/MTOR/BECLIN 1 AXIS IN ANNEXIN A1 REGULATED APOPTOSIS-AUTOPHAGY SWITCH IN CHEMORESISTANT COLORECTAL CANCER STEM-LIKE MODEL, THANUSHA M GANESAN
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(2024) Regulatory mechanism of HIFs-SIRT1-p53-miRNA axis in hepatocellular carcinoma tumourspheres cultured under hypoxic culture condition, SAKUNIE A/P SAWAI
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(2021) CELLULAR AND MOLECULAR SIGNATURES OF CANCER STEM-LIKE CELLS IN HEPATOCELLULAR CARCINOMA, AIN ZUBAIDAH BINTI AYOB
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(2017) COMPARATIVE MOLECULAR SIGNATURES OF HUMAN MESENCHYMAL STROMAL CELLS DURING IN VITRO PASSAGING, AUNG SHUH WEN
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(2016) Cellular and Molecular Signatures of Cancer Stem-Like Cells in Hepatocellular Carcinoma, Ain Zubaidah Ayob
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(2016) STIMULATION OF HAIR GROWTH USING CONDITIONED MEDIA DERIVED FROM DENTAL PULP STEM CELLS EXPANDED IN SERUM FREE MEDIA, THARINI NAWAMALIE ABEYSINGHE GUNAWARDENA
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(2016) THE EFFECT OF PLATELET RICH CONCENTRATE ON THE REGENERATIVE CAPACITY OF MESENCHYMAL STROMAL CELLS AND ITS POTENTIAL APPLICATION IN CARTILAGE REPAIR, SHANI SAMUEL
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(2016) ANGIOGENIC POTENTIAL OF HUMAN PLATELET RICH CONCENTRATES ON DENTAL PULP STEM CELLS IN AN IN-VITRO INFLAMMATION MODEL, PRIYADARSHNI BINDAL
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(2013) The Molecular Signatures of In Vitro Ageing in Human Mesenchymal stemcells, Aung Shuh Wen
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(2013) The Effect Of Platelet Rich Concentrate On The Regenerative Capacity Of Mesenchymal Stromal Cells And Its Potential Application In Cartilage Repair, Shani Samuel
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(2012) Stimulation Of Hair Growth Using Conditioned Media Derived From Dental Pulp Stem Cells Expanded In Serum Free Media, Tharini Gunawardena
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(2012) Angiogenic Potential Of Human Platelet Rich Concentrates On Dental Pulp Stem Cells In An In-Vitro Inflammation Model, Dr. Priya Bindal
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(2024) Chitosan-based nanoparticles for delivery of resveratrol to lung cancer, TAN KAH WEI
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(2021) Knowledge, awareness and perception of regenerative medicine among Medical Specialists in Malaysia, Dr. Ramizah Mohd Shariff (Ucsi University)
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(2021) Elucidation of global induction and repression of cancer-related pathways upon Sirtuin1 upregulation and downregulation in hypoxic vs normoxic HepG2, Nur Diyana Binti Zulkifli (Universiti Sains Malaysia (USM))
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(2018) Novel Approach for Attenuation and/or Reversal of Mesenchymal Stromal Cell Aging in Culture, YELENA YEOW MAY MIN
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(2018) The Role of Cell Cycle in Determintaion of Stem Cell Fate, YEW HONG WEN
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(2018) CYTOTOXIC EFFECT OF KONJAC GLUCOMANNAN ON THE MOLECULAR AND DIELECTRIC PROPERTIES OF HEPG2 AND WRL68 LIVER CELL LINES, SAKUNIE A/P SAWAI
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(2016) The Role of Cell Cycle in Determination of Stem Cell Fate, Yew Hong Wen
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(2016) Novel Approach for Attenuation and/or Reversal of Mesenchymal Stromal Cell Aging in Culture, Yelena Yeow May Min
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(2016) A study of the properties of treated and untreated liver cancer cells using molecular and biosensor techniques, Sakunie A/P Sawai
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(2015) Impact of educational talk on knowledge, awareness and perception of umblical cord stem cell banking, Dr. Dhivya Kanthaiyah (000000245)
Under Graduate Students
- (2023) Development of HepG2-derived tumoursphere model for studying drug response in hepatocellular carcinoma
- (2023) A study to investigate metabolic reprogramming in HepG2 cell-derived 3D tumourspheres
- (2023) A Study to Investigate Expression of p53 and Its Isoforms in HepG2 cell-derived 3D Tumourspheres
- (2019) Industrial Training Internship Program
TEACHING
Master
- (2017) MXGZ6101 - Research Methodology for Research Mode Programmes
- (2016) MXGZ6101 - Research Methodology for Research Mode Programmes
- (2015) MXGZ6101 - Research Methodology for Research Mode Programmes
Bachelor
- (2017) DIA1003 - Biochemistry (B. Dental Surgery)
- (2017) GIM2001 - Your Body and Its Health
- (2017) MBEB3105 - Applications and Advances in Molecular Biology
- (2017) UMMP - Block 11 (Oncology Ummp)
- (2017) UMMP - Block 2 (Oncology Ummp)
- (2016) DIA1003 - Biochemistry (B. Dental Surgery)
- (2016) GIM2001 - Your Body and Its Health
- (2016) UMMP - Block 11 (Oncology Ummp)
- (2016) UMMP - Block 2 (Foundation Ummp)
- (2015) DIA1003 - Biochemistry (B. Dental Surgery)
- (2015) MBEB3105 - Applications and Advances in Molecular Biology
- (2015) MIB1003 - Biochemistry (B. Pharmacy)
- (2015) MIB1003 - Biochemistry (B.Pharmacy)
- (2015) MTEJ2101 - Basic Medical Sciences
- (2015) SERU - Seru
- (2015) UMMP - Block 11 (Oncology Ummp)
- (2015) UMMP - Block 2 (Foundation Ummp)
- (2014) DIA1003 - Biochemistry (B. Dental Surgery)
- (2014) MIB1003 - Biochemistry (B. Pharmacy)
- (2014) UMMP - Block 11 (Oncology Ummp)
- (2014) UMMP - Block 2 (Foundation Ummp)
- (2013) DIA1003 - Biochemistry (B. Dental Surgery)
- (2013) MBBS - Phase 1 Biochemistry
- (2013) MWEF1106 - Biochemistry
- (2012) DBED1101 - Biochemistry
- (2012) MBBS - Problem Based Learning (Pbl)
- (2012) MBED - Phase 1 Biochemistry
- (2012) MIB1003 - Biochemistry (B.Pharmacy)
- (2012) MWEF1106 - Biochemistry
- () UMMP - Ummp, Block 2 (Oncology Ummp)
Others
- (2013) DMT1132 - Biochemistry
- (2012) DMLT1132 - Biochemistry
PATENT/IPR
- AGE Health Management Application for ElderlyCOPYRIGHT
- Age Health Management Application For ElderlyCOPYRIGHT
SOCIAL RESPONSIBILITY ACTIVITIES
- Skim Geran Pegawai Penyelidik Malaysian Research University Network (Mrun) (Mrogs), (12 Oct 2023 - 17 Nov 2023) (National)
- Judge, Young Inventors Challenge 2023, (12 Jun 2023 - 30 Jun 2023) (National)
- Judge, Young Inventors Challenge (Special Edition) 2020 (National), (01 May 2020 - 31 Jul 2020)
- Judge, Science Fair (March), Sek. Ren. Jen. Keb. (Tamil) Vivekananda, Brickfields, Kuala Lumpur, (25 Mar 2016 - 25 Mar 2016)
- Judge, Science Fair (April), Sek. Ren. Jen. Keb. (Tamil) Vivekananda, Brickfields, Kuala Lumpur, (25 Mar 2016 - 25 Mar 2016)