Curriculum Vitae

PROF. DR. SARGUNAN SOCKALINGAM

Professor
  • Department of Medicine
    Faculty of Medicine
  • sargunan
  • 03-7967 3213

BIOGRAPHY

 

Professor Dr. Sargunan Sockalingam is the former Head of Rheumatology at the University Malaya Medical Centre. He is a graduate of the Manipal Academy of Higher Education's Kasturba Medical College and completed both Masters in Internal Medicine and Rheumatology Subspecialty training in University Malaya. His research activities have focused on clinical trials using biologic therapy in Lupus and Rheumatoid Arthritis. He is currently working on developing a registry of rheumatology cases in UM. He is also a member of the Asia Pacific Lupus Collaboration.  His primary academic interest is the cellular and molecular basis of autoimmunity and speaks on this subject both within Malaysia and SEA. The Rheumatology unit in UMMC is the premier University based Rheumatology centre in the country and in addition to clinical work, it is a Rheumatology subspecialty training centre for both Malaysian and international physicians.

 

AREAS OF EXPERTISE

  • RHEUMATOLOGY

ACADEMIC QUALIFICATION

  • Fellowship (Rheumatology), (Consultancy Training in Rheumatology)
    University of New South Wales, Australia
  • MMEDINT, (PERUBATAN DALAMAN (INTERNAL MEDICINE))
    Universiti Malaya (UM)
  • MBBS, (PERUBATAN DAN PEMBEDAHAN)
    Kasturba Medical College, India

ADMINISTRATIVE DUTIES

  • Head of Unit
    01 Jan 2022 - 31 Dec 2022 (Department)
  • Head of Unit
    01 Aug 2014 - 01 Jul 2021 (University Malaya)
  • Head of Unit
    01 Aug 2016 - 01 Apr 2021 (Department of Medicine, Faculty of Medicine)
  • Programme Coordinator
    01 Mar 2016 - 01 Mar 2021 (University Malaya)
  • E-Document Manager
    01 Oct 2013 - 01 Oct 2016 (Department of Medicine, Faculty of Medicine)
  • Quality Manager
    21 Jun 2013 - 21 Jun 2016 (Department of Medicine, Faculty of Medicine)
  • Quality Manager
    02 Feb 2009 - 31 Dec 2010 (Department of Medicine, Faculty of Medicine)

MEMBERSHIPS

  • NATIONAL SPECIALIST REGISTRY, MEMBER
    Since 2010 (National)
  • ARTHRITIS FOUNDATION OF MALAYSIA, PRESIDENT/ CHIEF
    Since 2015 (University)

AWARD AND STEWARDSHIP

  • Jenssen Advanced Disease Education (JADE) - Dermatology and Rheumatology
    Jenssen Malaysia, 2020 (International)
  • JAK-inhibitor in Psoriatic Arthritis Advisory Board
    Pfizer Malaysia, 2020 (National)
  • WEBCAST SERIES: RHEUMATOLOGY IN THE TIME OF COVID-19
    MALAYSIAN SOCIETY OF RHEUMATOLOGY, 2020 (National)
  • UMMC LIVING LIBRARY 2019
    UNIVERSITY MALAYA MEDICAL CENTRE, 2019 (Department)
  • 23rd Annual International Conference of the Pakistan Society of Rheumatology - Speaker 1 - Undifferentiated Connective Tissue Disease 2- Neuropsychiatric SLE
    Pakistan Society of Rheumatology, 2019 (International)
  • NOVARTIS PRECEPTORSHIP ON SPONDYLOARTHRITIS (SpA)
    UHN TOTONTO WESTERN HOSPITAL, 2019 (International)
  • PLENARY LECTURE: HEART AND KIDNEYS IN HYPERURICEMIA
    PHILIPPINE RHEUMATOLOGY ASSOCIATION, 2019 (International)
  • RHEUMATOLOGY CONNECTS: SYMPOSIUM ON COMMON QUESTIONS, PRACTICAL ANSWERS THE PAINFUL SWOLLEN JOINT: ASK THE RIGHT QUESTIONS
    PHILIPPINE RHEUMATOLOGY ASSOCIATION, 2019 (International)
  • MANAGEMENT OF PSORIATIC ARTHRITIS AND SPONDYLOARTHROPATHY
    MALAYSIAN SOCIETY OF DERMATOLOGY, 2019 (National)
  • QEH MRCP (UK) PACES EXAM AND TEACHING
    Department of Medicine Queen Elizabeth Hospital, 2018 (National)
  • 22nd Pakistan Society for Rheumatology Annual International Conference Speaker : Sjogren's Syndrome - A Multisystem disease
    Pakistan Society for Rheumatology, 2018 (International)
  • 2018 Asia REACH Summit on Inflammation and Immunology
    Pfizer, 2018 (International)
  • MSR RHEUMATOLOGY TRAINING DAY 2018 SPEAKER NEUROLOGICAL MENAIFESTATIONS IN RHEUMATIC DISEASE
    PUSAT PERUBATAN UNIVERSITY MALAYA, 2018 (National)
  • Symposium of Reumatologi Klinik Bandung 2017 Speaker
    Reumatologi Klinik Bandung - Ikatan Reumatologi Indonesia, 2017 (International)
  • BALI RHEUMATOLOGY UPDATE - Diagnosis dan tatalaksana Sistemik Sklerosis
    IKATAN RHEUMATOLOGI INDONESIA, 2017 (International)
  • BALI RHEUMATOLOGY UPDATE - Diagnosis dan Tatalaksana SLE Berat
    IKATAN RHEUMATOLOGI INDONESIA, 2017 (International)
  • SYMPOSIUM ON ADVANCES OF BIOLOGIC THERAPY IN AUTOIMMUNE DISEASES SPEAKER - AUTOIMMUNITY AND AUTOIMMUNE DISEASES
    JOHNSON & jOHNSON - SOUTH EAST ASIA IMMUNOLOGY MASTERCLASS, 2016 (International)
  • MYANMAR RHEUMATOLOGY SOCIETY - SPEAKER: PITFALLS IN RA PAIN MANAGEMENT
    MYANMAR RHEUMATOLOGY SOCIETY, 2016 (International)
  • The 8th Sabah MMA Primary Care Conference - Speaker The Many Faces of SLE: How to recognize and what Primary Care doctors can do
    MALAYSIAN MEDICAL ASSOCIATION, 2016 (National)
  • LIVING WITH OSTEOARTHRITIS SEMINAR
    The PISA Rewsearch Group University Malaya, 2015 (University)
  • PLENARY SPEAKER at CLINICAL PROBLEM-SOLVING & CASE STUDIES IN ARTHRITIS, LUPUS AND RELATED CONDITIONS
    RHEUMATOLOGY EDUCATIONAL TRUST FOUNDATION, INC PHILIPPINES, 2015 (International)
  • 16TH ASIA PACIFIC LEAGUE OF ASSOCIATIONS OF RHEUMATOLOGY CONGRESS - Sustainable Rheumatology in Asia Plenary Speaker
    APLAR - Asia Pacific League of Association of Rheumatologists, 2014 (International)
  • Anugerah Perkhidmatan Cemerlang
    University Malaya, 2010 (University)
  • Standard Chartered KL Marathon 2009
    Malaysian Amateur Athletic Union, 2009 (International)
  • Certificate of Merit
    The Sun-Herald Australia, 2008 (International)
  • Sijil Penghargaan Ceramah
    Fakulti Pergigian University Malaya, 2007 (University)
  • Sijil Penghargaan Perkhidmatan/Layanan Cemerlang
    Pusat Perubatan Universiti Malaya, 2007 (University)

PUBLICATIONS

Article in Journal
WoS
  1. Cheah, Chia Wei; Al-Maleki, Anis Rageh; Vaithilingam, Rathna Devi; Vadivelu, Jamuna; Sockalingam, Sargunan; Baharuddin, Nor Adinar; Bartold, Peter Mark (2022). Associations between inflammation-related LL-37 with subgingival microbial dysbiosis in rheumatoid arthritis patients, CLINICAL ORAL INVESTIGATIONS. . doi:10.1007/s00784-022-04388-y
  2. Kandane-Rathnayake, Rangi; Louthrenoo, Worawit; Hoi, Alberta; Luo, Shue-Fen; Wu, Yeong-Jian J.; Chen, Yi-Hsing; Cho, Jiacai; Lateef, Aisha; Hamijoyo, Laniyati; Navarra, Sandra, V; Zamora, Leonid; Sockalingam, Sargunan; An, Yuan; Li, Zhanguo; Katsumata, Yasuhiro; Harigai, Masayoshi; Hao, Yanjie; Zhang, Zhuoli; Kikuchi, Jun; Takeuchi, Tsutomu; Basnayake, B. M. D. B.; Chan, Madelynn; Ng, Kristine Pek Ling; Tugnet, Nicola; Kumar, Sunil; Oon, Shereen; Goldblatt, Fiona; O'Neill, Sean; Gibson, Kathryn A.; Ohkubo, Naoaki; Tanaka, Yoshiya; Bae, Sang-Cheol; Lau, Chak Sing; Nikpour, Mandana; Golder, Vera; Morand, Eric F. (2022). 'Not at target': prevalence and consequences of inadequate disease control in systemic lupus erythematosus-a multinational observational cohort study, ARTHRITIS RESEARCH & THERAPY. 24(1). doi:10.1186/s13075-022-02756-3
  3. Kandane-Rathnayake, Rangi; Louthrenoo, Worawit; Luo, Shue-Fen; Wu, Yeong-Jian J.; Chen, Yi-Hsing; Golder, Vera; Lateef, Aisha; Cho, Jiacai; Navarra, Sandra, V; Zamora, Leonid; Hamijoyo, Laniyati; Sockalingam, Sargunan; An, Yuan; Li, Zhanguo; Montes, Ricardo; Oon, Shereen; Katsumata, Yasuhiro; Harigai, Masayoshi; Hao, Yanjie; Zhang, Zhuoli; Chan, Madelynn; Kikuchi, Jun; Takeuchi, Tsutomu; Goldblatt, Fiona; O'Neill, Sean; Bae, Sang-Cheol; Lau, Chak S.; Hoi, Alberta; Karyekar, Chetan S.; Nikpour, Mandana; Morand, Eric F. (2022). Patterns of Medication Use in Systemic Lupus Erythematosus: A Multicenter Cohort Study, ARTHRITIS CARE & RESEARCH. . doi:10.1002/acr.24740
  4. Lee, Y. H., Baharuddin, N. A., Chan, S. W., Rahman, M. T., Bartold, P. M., Sockalingam, S., & Vaithilingam, R. D. (2021). Localisation of citrullinated and carbamylated proteins in inflamed gingival tissues from rheumatoid arthritis patients. Clinical Oral Investigations, 25(3), 1441-1450. doi: 10.1007/s00784-020-03452-9
  5. Lew, P. H., Rahman, M. T., Safii, S. H., Baharuddin, N. A., Bartold, P. M., Sockalingam, S., . . . Vaithilingam, R. D. (2021). Antibodies against citrullinated proteins in relation to periodontitis with or without rheumatoid arthritis: a cross-sectional study. Bmc Oral Health, 21(1), 11. doi: 10.1186/s12903-021-01712-y
  6. Tan, C. Y., Ambang, T., Raja, J., Shahrizaila, N., Sockalingam, S., Suzuki, S., . . . Goh, K. J. (2021). Immune-mediated necrotizing myopathy in a multi-ethnic Malaysian cohort. Neurology Asia, 26(2), 291-299.
Others
  1. Connelly K, Kandane-Rathnayake R, Hoi A, Louthrenoo W, Hamijoyo L. (2022). Association of Modified Systemic Lupus Erythematosus Responder Index Attainment With Long-Term Clinical Outcomes: A Five-Year Prospective Study. Arthritis Rheumatol.2022 Sep 19. doi: 10.1002/art.42350.
  2. Rangi Kandane-Rathnayake, Vera Golder, Worawit Louthrenoo, Yi-Hsing Chen (2016). Lupus low disease activity state and remission and risk of mortality in patients with systemic lupus erythematosus: a prospective, multinational, longitudinal cohort study, The Lancet Rheumatology, Volume 4, Issue 12, 2022, Pages e822-e830, ISSN 2665-9913,
  3. Ing Soo Lau, Suk Chyn Gun, Swan Sim Yeap, Mollyza Mohd Zain, Habibah Mohd Yusoof, Sargunan Sockalingam, Fariz Yahya (2021). Algorithm for the referral of patients with inflammatory back pain from primary care in Malaysia. Malaysian Family Physician. 2021;16(2).
  4. Kandane-Rathnayake, R., Louthrenoo, W., Luo, S.-F., Wu, Y.-J.J., Chen, Y.-H., Golder, V., Lateef, A., Cho, J., Navarra, S.V., Zamora, L., Hamijoyo, L., Sockalingam, S., An, Y., Li, Z., Montes, R., Oon, S., Katsumata, Y., Harigai, M., Hao, Y., Zhang, Z., Chan, M., Kikuchi, J., Takeuchi, T., Goldblatt, F., O Neill, S., Bae, S.-C., Lau, C.S., Hoi, A., Karyekar, C.S., Nikpour, M., Morand, E.F. and (2021), Patterns of Medication Use in Systemic Lupus Erythematosus A Multi-Centre Cohort Study. Arthritis Care & Research
  5. Cheah CW, Al Maleki AR, Vadivelu J, Danaee M, Sockalingam S, Baharuddin NA, Vaithilingam RD. Salivary and serum cathelicidin LL 37 levels in subjects with rheumatoid arthritis and chronic periodontitis. Int J Rheum Dis 2020; https://doi.org/10.1111/1756-185X.13919
  6. Han PSH, Saub R, Baharuddin NA, Sockalingam S, Bartold PM, Vaithilingam RD (2020). Impact of periodontitis on quality of life among subjects with rheumatoid arthritis: a cross sectional study. BMC Oral Health 20:332 https://doi.org/10.1186/s12903-020-01275-4
  7. Lee HJ*, Pok LSL*, Ng CM, Yahya F, Sockalingam S, Tee YC, Raja J. Fatigue and associated factors in a multi-ethnic cohort of rheumatoid arthritis patients. Int J Rheum Dis. 2020;23:1088 1093. https://doi.org/10.1111/1756-185X.13897 (*co-first authors)
  8. Lee YH, Baharuddin NA, Chan SW, Rahman MT, Bartold PM, Sockalingam S, Vaithilingam RD. (2020) Localisation of citrullinated and carbamylated proteins in inflamed gingival tissues from rheumatoid arthritis patients. Clinical Oral Investigations. doi.org/ 10.1007/s00784-020-03452-9
  9. Leela Raman, Fariz Yahya, Choung Min Ng, Sargunan Sockalingam, Kuganathan Ramasamy, Ravinash Ratnam, Jasmin Raja (2020). Early damage as measured by SLICC/ACR damage index is a predictor of hospitalization in systemic lupus erythematosus (SLE). Lupus, Volume: 29 issue: 14, page(s): 1885-1891.
  10. Emery, P. (1996). Longterm Drug Survival of Tumor Necrosis Factor Inhibitors in Patients with Rheumatoid Arthritis
  11. Kandane-Rathnayake, R (2019) Longitudinal associations of active renal disease with irreversible organ damage accrual in systemic lupus erythematosus .Lupus, 28(14), 1669-1677
  12. Kandane-Rathnayake, R (2019). Development of the Asia Pacific Lupus Collaboration cohort, IJRD 22(3), 425-433
  13. Mat, S., Jaafar, M.H., Sockalingam, S., Raja, J., Kamaruzzaman, S.B., Chin, A.V., Abbas, A.A., Chan, C.K., Hairi, N.N., Othman, S., Cumming, R., Tan, M.P. (2018) Vitamin D deficiency is associated with ethnicity and knee pain in a multi-ethnic South-East Asian nation: Results from Malaysian Elders Longitudinal Research (MELoR). International Journal of Rheumatic Diseases, 21(5),930-936. doi: 10.1111/1756-185X.13279. Epub 2018 Apr 3. PMID: 29611292.
  14. Golder, V. (2017) Association of the lupus low disease activity state (LLDAS) with health-related quality of life in a multinational prospective study. Arthritis Research & Therapy, (2017), 19:62
  15. J.Raja, CT Ng, I.Sujau, KF Chin, S.Sockalingam. High-resolution oesophageal manometry and 24-hour impedance-pH study in systemic sclerosis patients: association with clinical features, symptoms and severity. Clinical and Experimental Rheumatology (Tier 2). 2016 Sep-Oct;34 Suppl 100(5):115-121
  16. Jasmin R, Sockalingam S, Ramanaidu L, Goh KJ.Clinical and electrophysiological characteristics of symmetric polyneuropathy in a cohort of systemic lupus erythematosus patients.Lupus. 2014 Sep 24.
  17. Khairullah S, Sulaiman H, Yahya F, Jasmin R, Cheah TE, Sockalingam S, Bick J, Chin Teck NG.Cryptococcal meningitis and SLE: a diagnostic and therapeutic challenge.Acta Reumatol Port. 2014 Jul-Sep;39(3):254-8. (ISI cited)
  18. R Jasmin, S Sockalingam, LP Ramanaidu, KJ Goh. Clinical and electrophysiological characteristics of symmetrical polyneuropathy in a cohort of systemic lupus erythematosus patients. Lupus. Published online 24 September 2014. DOI: 10.1177/0961203314552115. (ISI cited, Tier 2)
  19. Sujau I, Ng CT, Sthaneshwar P, Sockalingam S, Cheah TE, Yahya F, Jasmin R. Clinical and autoantibody profile in systemic sclerosis: baseline characteristics from a West Malaysian cohort. Int J Rheum Dis. 2014 Feb 23. doi: 10.1111/1756-185X.12322. (ISI cited, Tier 3)
  20. Sujau I1, Ng CT, Sthaneshwar P, Sockalingam S, Cheah TE, Yahya F, Jasmin R. Clinical and autoantibody profile in systemic sclerosis: baseline characteristics from a West Malaysian cohort.Int J Rheum Dis. 2014 Feb 23.
  21. Jasmin R, Ng CT, Sockalingam S, Fariz Y, Cheah TE, Athar S, Myocardial infarction with normal coronaries: an unexpected finding in a 13-year-old girl with systemic lupus erythematosus, Lupus 2013 22:1518-1522, originally published online 4 September 2013 DOI: 10.1177/0961203313503913. (ISI cited, Tier 2)
  22. Jasmin R, Sockalingam S, Cheah TE, Goh KJ, Systemic lupus erythematosus in the multiethnic Malaysian population: disease expression and ethnic differences re-visited, Lupus. 2013 Aug;22(9):967- 71. doi: 10.1177/0961203313496299. Epub 2013 Jul 11. (ISI cited, Tier 2)
  23. Khairullah S, Jasmin R, Yahya F, Cheah TE, Ng CT, Sockalingam S.Chronic intestinal pseudo-obstruction: a rare first manifestation of systemic lupus erythematosus.Lupus. 2013 Aug;22(9):957-60. doi: 10.1177/0961203313492873.(ISI cited, Tier 2)
  24. Ong CS, Cheah TE, Jasmin R, Yahya F, Sockalingam S, Ng CT.Painless ascites and elevated CA125: initial presentation of lupus-associated protein-losing enteropathy.Lupus. 2013 Oct;22(11):1174-7. doi: 10.1177/0961203313498792.(ISI cited, Tier 2)
  25. Wint Wint Thy Nyunt, Wah Yun Low, Rokiah Ismail, Sargunan Sockalingam, Aung Ko Ko Min. 2013. Determinants of health-related quality of life in psoriasis patients in Malaysia. Asia Pac J Public Health (in press).
  26. Yahya F, Jasmin R, Ng CT, Cheah TE, Sockalingam S.Open label randomized controlled trial assessing the efficacy of mycophenolate sodium against other conventional immunosuppressive agents in active systemic lupus erythematosus patients without renal involvement.Int J Rheum Dis. 2013 Dec;16(6):724-30. doi: 10.1111/1756-185X.12179.(ISI cited, Tier 3)
  27. Yahya, F., Jasmin, R., Ng, C. T., Cheah, T. E., Sockalingam, S. 2013. Open label randomized controlled trial assessing the efficacy of mycophenolate sodium against other conventional immunosuppressive agents in active systemic lupus erythematosus patients without renal involvement. International Journal of Rheumatic Diseases
  28. Analytical and diagnostic performance of an automated anti-CCP assay.Pavai S, Sargunan S, Zain AA, Chow SK.Malays J Pathol. 2011 Dec;33(2):101-6.
  29. CHEAH, T. E., JASMIN, R. and SOCKALINGAM, S. (2011), A combination of extraglandular manifestations of Sjogrens syndrome. International Journal of Rheumatic Diseases. doi: 10.1111/j.1756-185X.2011.01636.x (ISI cited, Tier 3)
  30. Case Report Mun Hoe Wong, Sargunan Sockalingam, Amir Zain.2011. Polymyositis associated with Hepatitis B: management with entacavir and prednisolone. International Journal of Rheumatic Diseases 14: e38-e41
  31. Pavai Sthaneshwar, Sargunan Sockalingam, Amir Zain & Chow Sook Khuan 2010. Analytical and diagnostic performance of an automated anti CCP assay.Malaysian Journal of Pathology.
  32. Jayaranee S, Sthaneshwar P, Sockalingam S 2009 Serum prohepcidin concentrations in rheumatoid arthritis Pathology 41(2): 178-82
  33. Sargunan SOCKALINGAM, Chow Sook KHUAN, Pavai STHANESHWAR 2009 Prevalence of anti cyclic citrullinated peptide antibodies in Malaysian rheumatoid arthritis patients and its correlation with disease activity. International Journal of rheumatic diseases vol 12 Issue 3(p 211-215)
  34. Sockalingam, S., Khuan, C. S., Sthaneshwar, P. 2009. Prevalence of anti cyclic citrullinated peptide antibodies in Malaysian rheumatoid arthritis patients and its correlation with disease activity. International Journal of Rheumatic Diseases
  35. Sockalingam G,Johnson K,Lassere M 2008 Clinical trials in SLE: a critical apprasial of study design, conduct, analysis and quality. Internal Medicine Journal 38(s2):a14
  36. Pavai S, Jayaranee S, Sargunan S 2007 Soluble transferrin receptor, ferritin and soluble transferrin receptor--Ferritin index in assessment of anaemia in rhaeumatoid arthritis.Med J Malaysia 62(4):303-7.
  37. S Kunanayagam, D Harichandra, S Sargunan 2007. Low Back Pain. Biomed Imaging Interv J 3(4):e10
Article in Proceeding
  1. Sockalingam G,Johnson K,Lassere M 2008 Clinical trials in SLE: a critical apprasial of study design, conduct, analysis and quality. Internal Medicine Journal 38(s2):a14
  2. SK Chow, S. Sargunan, HCK Loo.2006.Clinical manifestations and diagnostic tests of neuropsychiatric lupus. 12th APLAR Congress P629

RESEARCH PROJECT

National
  1. 2021 - 2025, Fundamental Research Grant Scheme (FRGS)
    Is Arg-gingipain Associated Netosis The Link Between Periodontitis And Rheumatoid Arthritis? ( Co-Researcher)
  2. 2013 - 2014, NONE
    A randomized, double-blind placebo-controlled study of the maintenance of efficacy of Etanercept plus DMARD(s) compared with DMARD(s) alone in subjects with rheumatoid arthritis after achieving an adequate response with Etanercept plus DMARD(s). ( Consultant)
  3. 2011 - 2013, Geran Penyelidikan Universiti Malaya (UMRG)
    Expression of TGF-beta receptor and TGF-beta signaling on T lymphocytes in patients with systemic lupus erythematosus (SLE). ( Consultant)
  4. 2011 - 2013, Geran Penyelidikan Universiti Malaya (UMRG)
    ASSESSMENT OF SYNOVITIS IN SMALL JOINTS OF RHEUMATOID ARTHRITIS PATIENTS AND THE NORMAL POPULATION ( Consultant)
  5. 2011 - 2013, Novartis
    Efficacy and Tolerability of Mycophenolate Sodium in patients with non renal active systemic lupus erythematosus. ( Principal Investigator(PI))
  6. 2012 - 2013, Postgraduate Research Grant(PPP)
    High-resolution manometry and 24-hour impedance-pH study in systemic sclerosis patients: association with clinical features, symptoms and severity. ( Co-Researcher)
  7. 2012 - 2013, Postgraduate Research Grant(PPP)
    Clinical and autoantibody profile in systemic sclerosis: baseline characteristics from a West Malaysian cohort. ( Co-Researcher)
  8. 2011 - 2012, Postgraduate Research Grant(PPP)
    Health related quality of life and Disease Severity in Patients with Psoriasis: A hospital-based cross sectional study in Malaysia ( Consultant)
  9. 2012 - 2012, NONE
    A Randomized, Double-blind, Placebo-controlled, Multiple Dose, Parallel, Multiple Dose-Level Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Clinical Effect of AMG 557 in Systemic Lupus Erythematosus (SLE) Subjects with Active Lupus Arthritis ( Consultant)
  10. 2010 - 2011, Postgraduate Research Grant(PPP)
    Peripheral Neuropathy in SLE in a Multiethnic Malaysian Population ( Co-Researcher)
  11. 2006 - 2007, Rheumatology Research Fund (CIC cluster)
    The sensitivity and specificity of anti CCP antibody among Malaysian Rheumatoid Arthritis patients and its correlation with disease activity and severity ( Principal Investigator(PI))
  12. 2006 - 2007, Fundamental Research Grant Scheme (FRGS)
    Serum prohepcidin concentrations in rheumatoid arthritis ( Consultant)
  13. 2004 - 2005, Rheumatology Research Fund (CIC cluster)
    The prevalence of anti CCP antibodies among Malaysian Rheumatoid Arthritis patients in University Malaya Medical Centre and its correlataion with disease activity and severity ( Principal Investigator(PI))
International
  1. 2015 - 2023, ScienceFund
    Asia Pacific Lupus Collaboration Database ( Principal Investigator(PI))
  2. 2012 - 2016, Janssen
    A multicenter, randomized, double-blind, placebo-controlled, parallel group study of CNTO 136 (sirukumab), a human anti-IL-6 monoclonal antibody, administered subcutaneously in subjects with active rheumatoid arthritis despite DMARD therapy ( Consultant)
  3. 2011 - 2013, Hoffman-La Roche
    A randomized double blind parallel group study of safety and the clinical outcome of toclizumab SC versus placebo SC in combination with traditional disease modifying anti-rheumatic drugs (DMARDs) in patients with moderate to severe active rheumatoid arthritis ( Principal Investigator(PI))

CONSULTANCY PROJECT

  • Clinical Practice Guidelines in Rheumatology (Rheumatoid Arthritis), Kementerian Kesihatan Malaysia
    01 Dec 2020 - 01 Dec 2021 (National)
  • Asia Rheumatology Expert Advisory Council for Health, Pfizer
    01 Dec 2012 - 01 Dec 2017 (International)

PAPER PRESENTED

INVITED SPEAKER
  1. The role of the Rheumatologist in the time of Covid19 - the UMMC experience, Rheumatology in the time of Covid19, Malaysian Society of Rheumatogy (International) (17 Apr 2020 - 17 Apr 2020)
POSTER PRESENTER
  1. A MULTI-E[2011] [THU0404] PERIPHERAL NEUROPATHY IN SYSTEMIC LUPUS ERYTHEMATOSUS A STUDY IN THNIC ASIAN POPULATION, EULAR conference, European League of Association of Rheumatologists (International) (25 May 2011 - 28 May 2011)
  2. Clinical trials in SLE: a critical apprasial of study design, conduct, analysis and quality, 50th Annual Scientific Meeting Australian Rheumatology Association (01 Feb 2008)
  3. Clinical Manifestations and Diagnostic tests of Neuropsychiatric Lupus, 12th APLAR Congress 2006 (Asia Pacific League of Association of Rheumatologists), APLAR organizing committee (International) (01 Aug 2006 - 05 Aug 2006)
OTHERS
  1. [2013] [AB0370] AN OPEN LABEL TRIAL ASSESSING THE EFFICACY OF MYCOPHENOLATE SODIUM IN ACTIVE SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS WITHOUT RENAL IMPAIRMENT , EULAR conference Madrid, European League of Association of Rheumatologists (International) (12 Jun 2013 - 15 Jun 2013)
  2. [2012] [AB0706] THE CLINICAL AND IMMUNOLOGICAL PROFILE OF SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) PATIENTS IN A MULTIETHNIC MALAYSIAN POPULATION, EULAR Conference Berlin 2012, Eurolpean League of Association of Rheumatologists (International) (06 Jun 2012 - 09 Jun 2012)
  3. (2012)(AB0832)The clinical profile of cases of inflammatory muscle disease in university of malaya medical centre (UMMC), EULAR Conference , European Union League of Association of Rheumatologists (International) (06 Jun 2012 - 09 Jun 2012)

ACADEMIC/PROF. SERVICES

Evaluation
  1. (2021) Visiting Professor Program for Teaching and Research in Lupus and Autoimmune Diseases, International, (External Evaluator)
  2. (2021) Examiner for Rheumatology Sub Specialty Qualification, National, (Internal Examiner)
  3. (2019) Clinical Practice Guidelines in Rheumatoid Arthritis , (Advisory Committee)
  4. (2014) Associate editor for International Journal of Rheumatic Diseases , (Editor)
  5. (2013) Associate Editor for International Journal of Rheumatic Diseases , (Editor)
  6. (2013) Th17 Cells in Immunopathogenesis and Treatment of Rheumatoid Arthritis, (Reviewer)
  7. (2013) Editor for the Joint Efforts Magazine which is a quarterly publication of the Arthritis Foundation of Malaysia, (Editor)
  8. (2013) Ref.: Ms. No. MJM-D-13-00129 Acute Gout in Hospitalized patients in Sarawak General Hospital., (Reviewer)
  9. (2013) A journey: Diagnosis of Fibromyalgia, (Reviewer)
  10. (2012) Hematological abnormalities in 624 patients with systemic lupus erythematosus at diagnosis and follow-up, and their relationship with organ involvement, (Reviewer)
  11. (2007) Reviewer for BIIJ Biomedical Imaging and Intervention Journal (SCOPUS), (Reviewer)
Contribution to external organisation
  1. (2025) Asia Pacific Lupus Collaboration , Monash University, International
  2. (2024) Asia Pacific Lupus Collaboration, International, (Research Fellow/Associate)
  3. (2021) Asean Psondyloarthritis (Psa/Axspa) Advisory Board 2021, International, (Expert Advisor)
  4. (2021) Clinical Practice Guidelines for Gout, National, (Resource Person)
Contribution to event
  1. (2021) Axial Psa Review of Aplar Conference, International, (Panelist/Moderator)
  2. (2021) Anca Associated Vasculitis - Landmark Trials, International, (Participant)
  3. (2021) Speaker Moving Forward for Rheumatology Patients, National, (Panelist/Moderator)

SUPERVISION

Postgraduate Student
PhD/ Doctoral
  1. (2022) Development of a referral intervention to improve communication between rheumatologists and periodontists in improving the rheumatology and oral health of patients with rheumatoid arthritis, and to assess its feasibility in clinical practice, Caroline Chin kwong leng
  2. (2020) Serum cathelicidin LL-37 levels is increased in patients with rheumatoid arthritis (RA), chronic periodontitis (CP), and both CP and RA, Cheah Chia Wei
Master
  1. (2020) Training of in Rheumatology Subspecialty, Ibrahim Sujau
  2. (2019) FATIGUE AND ASSOCIATED FACTORS IN A MULTI-ETHNIC COHORT OF RHEUMATOID ARTHRITIS PATIENTS, Tee Ying Chew
  3. (2019) FATIGUE AND ASSOCIATED FACTORS IN A MULTI-ETHNIC COHORT OF RHEUMATOID ARTHRITIS PATIENTS, Lydia Pok Say Lee
  4. (2012) Autoantibody profiles in Systemic Sclerosis and their clinical correlation among Systemic Sclerosis patients in University |Malaya Medical Centre, Ibrahim Sujau
  5. (2010) The prevalence of Peripheral Neurpoathy among patients with Systemic Lupus Erythematosus, Raja Jasmin Begum bt Raja Mohamed
  6. (2009) The clinical significance of anti nucleosome antibody in patients with Systemic Lupus Erythematosus and its correlation with disease activity in comparison with anti ds DNA, Hazlynna Baharuddin
  7. (2006) The sensitivity and specificity of anti CCP antibody in Rheumatoid Arthrtis patients in UMMC and its correlation with disease activity and severity, Zulkornain Ahmad
Under Graduate Students
  1. (2012) epidemiology of inflammatory muscle disorders among UMMC patients and epidemiology of Lupus among UMMC patients

TEACHING

Master
  1. (2021) Master - Internal Medicine
  2. (2021) NA - Master Internal Medicine
  3. (2019) MASTERS -
  4. (2012) Masters Medicine (Internal Medicine)
  5. (2011) Masters Medicine (Internal Medicine)
  6. (2009) Masters Medicine (Internal Medicine)
  7. (2007) Masters Medicine (Internal Medicine)
  8. (2006) Masters Medicine (Internal Medicine)
Bachelor
  1. (2021) UMMP - 3.3
  2. (2021) NA - Ummp Stage 1
  3. (2021) UMMP - Ummp Stage 2
  4. (2021) UMMP - MBBS
  5. (2012) MBBS
  6. (2010) Medicine
  7. (2008) Medicine
  8. (2007) Dental (Medicine)

PATENT/IPR

  • CPG Rheumatoid Arthritis Malaysia
    Copyright (National)

SOCIAL RESPONSIBILITY ACTIVITIES

  • President of The Arthritis Foundation of Malaysia, (01 Apr 2014 - 01 Apr 2018)
  • Arthritis Foundation of Malaysia Executive Member, (01 Jan 2014)
  • Speaker and Participant At The Postgraduate Rheumatology Course Manila, Philippines., (24 Nov 2013 - 25 Nov 2013)
  • Lecture for House Officers On Discharge Summary., (09 Jan 2013)
  • Active Member of Afm and Speaker for World Arthritis Day, (01 Jan 2013 - 31 Dec 2013)
  • Master of Ceremonies for The Aplar Scientific Congress 2006 Closing Ceremony., (01 Aug 2006 - 05 Aug 2006)