Curriculum Vitae

DR. SANTHERALEKA A/P RAMANATHAN

Senior Lecturer
  • Department of Chemical Engineering
    Faculty of Engineering
  • santheraleka

BIOGRAPHY

Dr. Santheraleka Ramanathan is a Senior Lecturer in the Department of Chemical Engineering at Universiti Malaya since 2025. She earned her Ph.D. in Nanobiotechnology Engineering in 2020 and gained research experience as a postdoctoral fellow at Universiti Teknologi Malaysia from 2021 to 2023. Dr. Santheraleka's research focuses on biosensors, nanomaterials, and nanodiagnostics, with an emphasis on molecular imprinting for environmental sustainability and biomedical applications. She specializes in synthesizing nanomaterials from environmental waste and integrating them into diagnostic platforms for detecting non-communicable disease biomarkers. Her expertise includes electrode fabrication, sensing platform surface chemistry, and analytical techniques. She actively develops molecularly imprinted polymer (MIP)-based sensors for environmental monitoring, targeting pollutants such as heavy metals, pesticides, and pharmaceuticals. As a passionate educator, Dr. Santheraleka is dedicated to inspiring lifelong learning by fostering a positive classroom environment and empowering the next generation of learners with wisdom toward knowledge and innovation.

ACADEMIC QUALIFICATION

  • PHD(NANOBIOTECHENG)(UNIMAP,MALAYSIA)(2020), (Nanobiotechnology Engineering)
    Universiti Malaysia Perlis (Unimap)
  • BEng (Hons) Bioprocess Eng. (UNIMAP,MALAYSIA)(2017), (Kejuruteraan Bioproses)
    Universiti Malaysia Perlis (Unimap)

MEMBERSHIPS

  • PROFESSIONAL ENGINEER, BOARD OF ENGINEERS MALAYSIA, PROFESSIONAL ENGINEER
    Since 2023 (National)

PUBLICATIONS

Article in Journal
  1. Gopinath, S. C. B., Ramanathan, S., More, M., Patil, K., Patil, S. J., Patil, N., Mahajan, M., & Madhavi, V. (2023). A Review on Graphene Analytical Sensors for Biomarker-based Detection of Cancer. Current Medicinal Chemistry, 31. https://doi.org/10.2174/0929867331666230912101634
  2. Natarajan, E., Chouhan, A., Ramanathan, S., Markandan, K., Mozhuguan Sekar, S., Ang, C. K., Deivanayagampillai, N., & Franz, G. (2024). Tailored Compositions of Ni-Ti-Sn Nanopowders Deposited on Polymer Fiber Optics Through Flash Evaporation. Journal of Composites Science, 8(12), 526. https://doi.org/10.3390/jcs8120526
  3. Ramanathan, S., Lau, W. J., Goh, P. S., Gopinath, S. C. B., Rawindran, H., Omar, M. F., Ismail, A. F., Breadmore, M. C., & See, H. H. (2024). Tailoring molecularly imprinted polymer on titanium-multiwalled carbon nanotube functionalized gold electrode for enhanced chlorophyll determination in microalgae health assessment. Microchimica Acta, 191(10). https://doi.org/10.1007/s00604-024-06662-0
  4. Ramanathan, S., Lau, W. J., Goh, P. S., Omar, M. F., Breadmore, M. C., Ismail, A. F., & See, H. H. (2024). Emerging interest of gold-carbon nanocomposites in water remediation: A new way forward. In Journal of Environmental Chemical Engineering (Vol. 12, Issue 3). Elsevier Ltd. https://doi.org/10.1016/j.jece.2024.112931
  5. Thirugnanasambandan, T., Ramanathan, S., & Gopinath, S. C. B. (2024). Revolutionizing biosensing through cutting-edge nanomaterials: An in-depth exploration of recent technological advances. In Nano-Structures and Nano-Objects (Vol. 38). Elsevier B.V. https://doi.org/10.1016/j.nanoso.2024.101128
  6. Ramanathan, S., Malarvili, M. B., & Gopinath, S. C. B. (2023). Assessing respiratory complications by carbon dioxide sensing platforms: Advancements in infrared radiation technology and IoT integration. Arabian Journal of Chemistry, 16(2), 104478. https://doi.org/10.1016/j.arabjc.2022.104478
  7. Ghosh, A., Gopinath, S. C. B., Firdous, S. M., & Ramanathan, S. (2022). Early detection of viral DNA in breast cancer using fingered aluminium interdigitated electrode modified by Streptavidin-biotin tetravalent complex. Journal of the Indian Chemical Society, 99(8). https://doi.org/10.1016/j.jics.2022.100604
  8. Gopinath, S. C. B., Ramanathan, S., Chinni, S. V., Dorairaj, V., & Lakshmipriya, T. (2022). Non-protein coding RNA sequences mediate specific colorimetric detection of Staphylococcus aureus on unmodified gold nanoparticles. Scientific Reports, 12(1). https://doi.org/10.1038/s41598-022-16551-2
  9. Gopinath, S. C. B., Ramanathan, S., Mohd Yasin, M. N., Shapiai Razak, M. I., Ismail, Z. H., Salleh, S., Sauli, Z., Malarvili, M. B., & Subramaniam, S. (2022). Failure analysis on silicon semiconductor device materials: optical and high-resolution microscopic assessments. Journal of Materials Research and Technology, 21, 3451–3461. https://doi.org/10.1016/j.jmrt.2022.10.116
  10. Ramanathan, S., Gopinath, S. C. B., Hilmi Ismail, Z., & Subramaniam, S. (2022). Nanodiamond conjugated SARS-CoV-2 spike protein: electrochemical impedance immunosensing on a gold microelectrode. Microchimica Acta, 189(6). https://doi.org/10.1007/s00604-022-05320-7
  11. Ramanathan, S., Gopinath, S. C. B., Ismail, Z. H., Md Arshad, M. K., & Poopalan, P. (2022). Aptasensing nucleocapsid protein on nanodiamond assembled gold interdigitated electrodes for impedimetric SARS-CoV-2 infectious disease assessment. Biosensors and Bioelectronics, 197. https://doi.org/10.1016/j.bios.2021.113735
  12. Anbu, P., Gopinath, S. C. B., Saravanakumar, K., Vijayakumar, S., Ramanathan, S., & Wang, M. H. (2021). Bimetallic mixed metal oxide (CuO/NiO) in fusion with nitrogen-doped graphene oxide: An alternate approach for developing potential biocarrier. Journal of Environmental Chemical Engineering, 9(4), 105781. https://doi.org/10.1016/j.jece.2021.105781
  13. Gopinath, S. C. B., Ramanathan, S., Yasin, M. N. M., Shapiai, M. I., Ismail, Z. H., & Subramaniam, S. (2021). Essential semiconductor films in micro-/nano-biosensors: Current scenarios. Journal of the Taiwan Institute of Chemical Engineers, 127, 302–311. https://doi.org/10.1016/j.jtice.2021.07.036
  14. Krishnan, H., Gopinath, S. C. B., Md. Arshad, M. K., Zulhaimi, H. Ii., & Ramanathan, S. (2021). Molecularly imprinted polymer amalgamation on narrow-gapped Archimedean-spiral interdigitated electrodes: resistance to electrolyte fouling in acidic medium. Microchimica Acta, 188(4), 1–12. https://doi.org/10.1007/s00604-021-04794-1
  15. Md Shakhih, M. F., Rosslan, A. S., Noor, A. M., Ramanathan, S., Lazim, A. M., & Wahab, A. A. (2021). Review-Enzymatic and Non-Enzymatic Electrochemical Sensor for Lactate Detection in Human Biofluids. Journal of The Electrochemical Society, 168(6), 067502. https://doi.org/10.1149/1945-7111/ac0360
  16. Murugasenapathi, N. K., Ghosh, R., Ramanathan, S., Ghosh, S., Chinnappan, A., Mohamed, S. A. J., Esther Jebakumari, K. A., Gopinath, S. C. B., Ramakrishna, S., & Palanisamy, T. (2023). Transistor-Based Biomolecule Sensors: Recent Technological Advancements and Future Prospects. In Critical Reviews in Analytical Chemistry (Vol. 53, Issue 5, pp. 1044–1065). Taylor and Francis Ltd. https://doi.org/10.1080/10408347.2021.2002133
  17. Ramanathan, S., Poopalan, P., Gopinath, S. C. B., Md Arshad, M. K., Anbu, P., Lakshmipriya, T., Salimi, M. N., & Pandian, K. (2021). Surface charge transduction enhancement on nano-silica and - Alumina integrated planar electrode for hybrid DNA determination. Materials Chemistry and Physics, 265(July 2020), 1–11. https://doi.org/10.1016/j.matchemphys.2021.124486
  18. Kalaiyarasi, J., Pandian, K., Ramanathan, S., & Gopinath, S. C. B. (2020). Graphitic carbon nitride/graphene nanoflakes hybrid system for electrochemical sensing of DNA bases in meat samples. Scientific Reports, 10(1). https://doi.org/10.1038/s41598-020-69578-8
  19. Ramanathan, S., Gopinath, S. C. B., & Arshad, M. K. (2020). Aluminosilicate Nanocomposites from Incinerated Chinese Holy Joss Fly Ash : A Potential Nanocarrier for Drug Cargos. Scientific Reports, 10(3351). https://doi.org/10.1038/s41598-020-60208-x
  20. Ramanathan, S., Gopinath, S. C. B., Arshad, M. K. M., & Poopalan, P. (2020). Nanostructured aluminosilicate from fly ash: Potential approach in waste utilization for industrial and medical applications. Journal of Cleaner Production, 253. https://doi.org/10.1016/j.jclepro.2019.119923
  21. Ramanathan, S., Gopinath, S. C. B., Arshad, M. K. M., Poopalan, P., Anbu, P., Lakshmipriya, T., & Lee, C. G. (2020). Alkalinized extraction of silica-aluminium nanocomposite from traditional Chinese joss paper: Optical characterizations. Materials Chemistry and Physics, 243(January), 122621. https://doi.org/10.1016/j.matchemphys.2020.122621
  22. Ramanathan, S., Jusoh, M., Sabapathy, T., Yasin, M. N., Gopinath, S. C. B., ARahim, H., Osman, M. N., & Wahab, Y. A. (2020). Elastomeric polydimethylsiloxane polymer on conductive interdigitated electrode for analyzing skin hydration dynamics. Applied Physics A: Materials Science and Processing, 126(9). https://doi.org/10.1007/s00339-020-03933-
  23. Adam, H., Gopinath, S. C. B., Md Arshad, M. K., Ramanathan, S., Ashokkumar, T., Azan, M. I. A., Adam, T., & Hashim, U. (2019). Fabrication of gold nanorod–zinc oxide nanocomposite on gap-fingered integrated interdigitated aluminum electrodes and their response to electrolytes. Applied Physics A: Materials Science and Processing, 125(12), 1–11. https://doi.org/10.1007/s00339-019-3106-7
  24. Ramanathan, S., Gopinath, S. C. B., Arshad, M. K. M., Poopalan, P., & Anbu, P. (2019). A DNA based visual and colorimetric aggregation assay for the early growth factor receptor (EGFR) mutation by using unmodified gold nanoparticles. Microchimica Acta, 186(8). https://doi.org/10.1007/s00604-019-3696-y
  25. Ramanathan, S., Gopinath, S. C. B., Arshad, M. K. M., Poopalan, P., Anbu, P., Lakshmipriya, T., & Kasim, F. H. (2019). Aluminosilicate Nanocomposite on Genosensor: A Prospective Voltammetry Platform for Epidermal Growth Factor Receptor Mutant Analysis in Non-small Cell Lung Cancer. Scientific Reports, 9(1), 1–11. https://doi.org/10.1038/s41598-019-53573-9
  26. Ramanathan, S., Gopinath, S. C. B., Md Arshad, M. K., Poopalan, P., Loong, F. K., Lakshmipriya, T., & Anbu, P. (2019). Assorted micro-scale interdigitated aluminium electrode fabrication for insensitive electrolyte evaluation: zeolite nanoparticle-mediated micro- to nano-scaled electrodes. Applied Physics A, 125(8), 548. https://doi.org/10.1007/s00339-019-2833-0
  27. Ramanathan, S., Gopinath, S. C. B., Md. Arshad, M. K., & Poopalan, P. (2019). Multidimensional (0D-3D) nanostructures for lung cancer biomarker analysis: Comprehensive assessment on current diagnostics. Biosensors and Bioelectronics, 141(May), 111434. https://doi.org/10.1016/j.bios.2019.111434
  28. Gopinath, S. C. B., Ramanathan, S., Hann Suk, K., Ee Foo, M., Anbu, P., & Uda, M. N. A. (2018). Engineered nanostructures to carry the biological ligands. MATEC Web of Conferences, 150, 06002. https://doi.org/10.1051/matecconf/201815006002
  29. Ramanathan, S., Gopinath, S. C. B., Anbu, P., Lakshmipriya, T., Kasim, F. H., & Lee, C. G. (2018). Eco-friendly synthesis of Solanum trilobatum extract-capped silver nanoparticles is compatible with good antimicrobial activities. Journal of Molecular Structure, 1160, 80–91. https://doi.org/10.1016/j.molstruc.2018.01.056
  30. Ramanathan, S., & Gopinath, S. C. B. (2017). Potentials in synthesizing nanostructured silver particles. Microsystem Technologies, 23(10), 4345–4357. https://doi.org/10.1007/s00542-017-3382-0
Books
  1. Malarvili, M., Aik Howe, T., Ramanathan, S., Alexie, M., & Prakash Singh, O. (2023). Systems and Signal Processing of Capnography as a Diagnostic Tool for Asthma Assessment.
Chapter in Books
  1. Ramanathan, S., Malarvili, M.B., Gopinath, S.C.B., Nindhia, T.G.T. (2024). Coronavirus Anatomy and Its Analytical Approaches for Targeting COVID-19. In: Rezaei, N. (eds) The COVID-19 Aftermath. Advances in Experimental Medicine and Biology, vol 1457. Springer, Cham. https://doi.org/10.1007/978-3-031-61939-7_2
  2. Ramanathan, S., & Malarvili, M. B. (2023). Capnography signal processing in trend with Industry 4.0 advancement. In Advanced Signal Processing for Industry 4.0, Volume 1: Evolution, communication protocols, and applications in manufacturing systems (pp. 2.1-2.23). Institute of Physics Publishing. https://doi.org/10.1088/978-0-7503-5247-5ch2
  3. Ramanathan, S., Gopinath, S. C. B., Poopalan, P., & Perumal, V. (2020). Nanoparticle synthetic methods: strength and limitations. In Nanoparticles in Analytical and Medical Devices (pp. 1–13).
  4. Ramanathan, S., Gopinath, S. C. B., Arshad, M. K. M., Poopalan, P., Perumal, V., & Saheed, M. S. M. (2019). Antimicrobial Property of Biosynthesized Silver Nanoparticles. In Nanomaterials for Healthcare, Energy and Environment, Advanced Structured Materials (pp. 87–101). Springer Singapore. https://doi.org/10.1007/978-981-13-9833-9
Article in Proceeding
  1. Ramanathan, S., Gopinath, S. C. B., Anbu, P., & Selvarajan, R. S. (2024). Analytical characterization of engineered nanostructures – Techniques and challenges. PROCEEDINGS OF 5TH INTERNATIONAL CONFERENCE ON SUSTAINABLE INNOVATION IN ENGINEERING AND TECHNOLOGY 2023, 3161, 020063. https://doi.org/10.1063/5.0229334