PERSONAL DETAIL


PROF. DR. ROSMAWATI BINTI MOHAMED

Department of Medicine
Faculty of Medicine
 
  rosmohamed@um.edu.my
 Department of Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, W.Persekutuan Kuala Lumpur, Malaysia
 
ResearcherID Link
  http://www.researcherid.com/rid/B-9617-2010

ACADEMIC QUALIFICATION
(Qualification), (Institution).



PROFESSIONAL
(Organisation), (Role), (Year), (Level).


  • ROYAL COLLEGE OF PHYSICIANS OF THE UNITED KINGDOM, Member, 2001, (International)
  • ASIAN PACIFIC ASSOCIATION FOR THE STUDY OF THE LIVER, Advisor And Member, 2004, (International)
  • MALAYSIAN SOCIETY OF GASTROENTEROLOGY AND HEPATOLOGY, President (2004-2005), 2005, (National)
  • Member of the Editorial Board, Hepatology International 2006-ongoing, Board Member, 2006, (International)
  • College Of Physicians, Academy Of Medicine Of Malaysia, Council Member, 2007, (National)
  • ACADEMY OF MEDICINE OF MALAYSIA, Council Member, 2007 to 2017, (National)
  • CHRONIC HEPATITIS B GUIDELINE WORKING PARTY OF THE ASIAN-PACIFIC ASSOCIATION FOR THE STUDY OF THE LIVER,, Committee Member, 2007, (International)
  • Asian Pacific Association for the Study of the Liver (APASL) Live Data Share and Consensus Development on Acute on Chronic Liver Failure , Committee Member, 2008, (International)
  • ASIA PACIFIC WORKING PARTY ON PREVENTION OF HEPATOCELLULAR CARCINOMA , Committee Member, 2008, (International)
  • Technical Advisory Committee on Clinical Practice Guidelines, Ministry of Health, Malaysia, Chairman, 2008, (National)
  • Coalition to Eradicate Viral Hepatitis in Asia Pacific (CEVHAP) , Council Member, 2010, (International)
  • COLLEGE OF PHYSICIANS, MALAYSIA, 1st Vice President, 2012, (National)
  • International Coalition of Hepatology Education Providers, Council Member, 2013 to 2017, (International)
  • Academy of Medicine of Malaysia, Secretary General, 2013, (National)
  • World Health Organisation, Global strategic Advisory Committee for Viral Hepatitis, Chairman, 2014 to  , (International)
  • the European Association for the Study of the Liver , Active Member, 2015, (International)
  • ASIAN PACIFIC ASSOCIATION FOR THE STUDY OF THE LIVER, Executive Council Member, 2017 to 2018, (International)
  • Academy of Medicine Malaysia, President, 2017, (National)

ADMINISTRATIVE DUTIES
(Role), (Level), (Start date),(End Date).


  • Deputy Dean, Dean's Office, Faculty of Medicine, 01/09/2009 to 22/04/2011
  • Deputy Dean, Dean's Office, Faculty of Medicine, 01/09/2007 to 31/08/2009
  • Deputy Dean, Dean's Office, Faculty of Medicine, 01/09/2006 to 31/08/2007
  • Deputy Dean, Dean's Office, Faculty of Medicine, 01/04/2006 to 31/08/2006
  • Deputy Dean, Dean's Office, Faculty of Medicine, 05/04/2004 to 31/03/2006
  • Wakil GantiTetap Dekan, University Malaya, 26/01/2018 to 25/01/2021 (Jawatankuasa Rayuan Universiti)
  • Coordinator, Faculty, 12/11/2017 to 31/12/2018 (ongoing since 12 Nov 2015)
  • Deputy Dean of Higher Degree, Faculty, 01/09/2009 to 21/04/2011
  • Deputy Dean of Research, Faculty, 05/04/2004 to 31/08/2009

AREAS OF EXPERTISE
(Area).


  • Hepatology (Viral Hepatitis, Hepatitis B, Hepatitis C, Fatty Liver, Hepatocellular Carcinoma)


RECENT SELECTED PUBLICATIONS
(Publication).


Chapter in Book

2014
  • Text Book of Hepato-Gastroenterology 
Article in Academic Journals

2018
  • Azzeri A, Shabaruddin FH, , Tan SS, Dahlui M, McDonald SA, Kamarulzaman A, Mohamed R. CLINICAL CHARACTERISTICS OF PATIENTS WITH CHRONIC HEPATITIS C INFECTION AT INITIAL PRESENTATION TO TERTIARY CARE IN AN ASIAN MIDDLE-INCOME COUNTRY (ISI-Indexed)
  • Barathan M, Mohamed R, Yong YK, Kannan M, Vadivelu J, Saeidi A, Larsson M, Shankar EM. Viral Persistence and Chronicity in Hepatitis C Virus Infection: Role of T-Cell Apoptosis, Senescence and Exhaustion. Cells. 2018 Oct 12;7(10). pii: E165. doi: 10.3390/cells7100165 (ISI-Indexed)
  • Raihan R, Azzeri A, H Shabaruddin F, Mohamed R. Hepatocellular Carcinoma in Malaysia and Its Changing Trend. Euroasian J Hepatogastroenterol. 2018;8(1):54-56. doi: 10.5005/jp-journals-10018-1259 (ISI-Indexed)

2017
  • Chan HLY, Chen CJ, mede O, et al. The present and future disease burden of hepatitis C virus infections with today's treatment paradigm. J Viral Hepat. 2017;24(Suppl. 2):25-43. doi.org/10.1111/jvh.12760 (ISI-Indexed)
  • Behnaz Riazalhosseini, Rosmawati Mohamed, Devi Apalasamy, Mbongo Langmia, Zahurin Mohamed: Circulating microRNA as a marker for predicting liver disease progression in patients with chronic hepatitis B. Revista da Sociedade Brasileira de Medicina Tropical 04/2017; 50(2):161-166., DOI:10.1590/0037-8682-0416-2016 (ISI-Indexed)
  • Yong YK, Tan HY, Saeidi A, Rosmawati M, et al. Decrease of CD69 levels on TCR Vα7.2+CD4+ innate-like lymphocytes is associated with impaired cytotoxic functions in chronic hepatitis B virus-infected patients. Innate Immun. 2017 Jul;23(5):459-467 (ISI-Indexed)
  • Blach S, and The Polaris Observatory HCV Collaborators. Global prevalence and genotype distribution of hepatitis C virus infection in 2015: a modelling studyLancet Gastroenterol Hepatol 2017;2:161–76 (ISI-Indexed)
  • Barathan M, Mohamed R, et al. CD8+ T cells of chronic HCV-infected patients express multiple negative immune checkpoints following stimulation with HCV peptides. Cell Immunol. 2017 Mar;313:1-9 (ISI-Indexed)

2016
  • Suzanne Wait, Emily Kell, Saeed Hamid, David H Muljono, Jose Sollano, Rosmawati Mohamed, Samir Shah, Mamun-Al-Mahtab, Zaigham Abbas, Jennifer Johnston, Tawesak Tanwandee, Jack Wallace (2016). Hepatitis B and hepatitis C in southeast and southern Asia: challenges for governments. Lancet Gastroenterol Hepatol, 1, 248–55. (ISI-Indexed)
  • Alsalahi A, Alshawsh MA, Mohamed R, Alyousefi NA, Alshagga MA, Shwter AN, Al-Maqtari A, Ahmed RH, Mohamed Z. Conflicting Reports on the Role of the Glycemic Effect of Catha edulis (Khat): A Systematic Review and Meta-analysis. J Ethnopharmacol. 2016 Jun 20;186:30-43 (ISI-Indexed)
  • 1. Hwa-li Tana, Rosmawati Mohamed, Zahurin Mohamed, Shamsul Mohd Zain. Phosphatidylethanolamine N-methyltransferase gene rs7946 polymorphism plays a role in risk of non-alcoholic fatty liver disease: Evidence from meta-analysis. Pharmacogenetics and Genomics 2016 Feb;26(2):88-95 (ISI-Indexed)
  • Behnaz Riazalhosseini, Zahurin Mohamed, Yamunah D Apalasamy, Rosmawati Mohamed. Association between microRNA-196A2 and microRNA-146A polymorphisms and progression to cirrhosis and hepatocellular carcinoma in patients with viral hepatitis B. Pharmacogenetics and Genomics 2016;26(2):74-9.3.48 (ISI-Indexed)

2015
  • McDonald SA, Dahlui M, Mohamed R, Naning H, Shabaruddin FH, et al. (2015) Projections of the Current and Future Disease Burden of Hepatitis C Virus Infection in Malaysia. PLoS ONE 10(6): e0128091. doi: 10.1371/journal.pone.0128091 (ISI-Indexed)
  • Lim SG, Amarapurkar DN, Chan HLY, et al. Reimbursement policies in the Asia-Pacific for CHRONIC Hepatitis B. Hepatology International 2015;9(1): 43-51 (ISI-Indexed)
  • Barathan M, Gopal K, Mohamed R, Ellegard R, Saeidi A, Vadivelu J, Ansari AW, Rothan HA, Ravishankar Ram M, Zandi K, Chang LY, Vignesh R, Che KF, Kamarulzaman A, Velu V, Larsson M, Kamarul T, Shankar EM. Chronic hepatitis C virus infection triggers spontaneous differential expression of biosignatures associated with T cell exhaustion and apoptosis signaling in peripheral blood mononucleocytes. Apoptosis. 2015 Jan 11. [Epub ahead of print] (ISI-Indexed)

2014
  • Zain SM, Mohamed Z, Rosmawati Mohamed. A common variant in the glucokinase regulatory gene rs780094 and risk of non-alcoholic fatty liver disease: A meta- analysis. J Gastroenterol Hepatol. 2014 Aug 28. doi: 10.1111/jgh.12714 (ISI-Indexed)
  • Zain SM, Rosmawati M, Cooper D, Razali R, Rampal S, Mahadeva S, Chan WK, Anwar A, Nurul SMR, Anis SF, Cheah PL, Basu RC, Tan HL, Mohamed Z. Genome-wide analysis of copy number variation identifies candidate gene loci associated with the progression of non- alcoholic fatty liver disease. PLOS ONE 2014;9 (4):e95604 , PLOS ONE 9(4):E95604 APRIL 2014. Impact Factor: 3.53. DOI: 10.1371/journal.pone.0095604 (ISI-Indexed)
  • Ahmad Najib Azmi, Soek-Siam Tan, Rosmawati Mohamed. Practical Approach In Hepatitis B e Antigen-negative Individuals To Identify Treatment Candidates. World Journal of Gastroenterology 2014 (ISI-Indexed)

2013
  • Lye SH, Chahil JK, Bagali P, Alex L, Vadivelu J, Ahmad WA, Chan SP, Thong MK, Zain SM, Mohamed R (2013) Genetic polymorphisms in LDLR, APOB, PCSK9 and other lipid related genes associated with Familial hypercholesterolemia in Malaysia. PLOS ONE Volume 8 | Issue 4 | e60729 (ISI-Indexed)
  • Ng, Chirk Jenn, Low, W.Y., Wong, L.P., Mohd Ridwan Sudin, & Rosmawati Mohamed. 2013. Uncovering the experiences and needs of patiens with chronic Hepatitis B infection at diagnosis: A qualitative study. Asia Pac J Public Health 25(1): 32-40 (ISI/SCOPUS Indexed Publication)
  • Shamsul Mohd Zain,*, Zahurin Mohamed,*, Sanjiv Mahadeva, Phaik-Leng Cheah, Sanjay Rampal, Kin-Fah Chin, Roma Choudhury Basu,** Hwa-Li Tan*, and Rosmawati Mohamed (2013). Impact of leptin receptor gene variants on risk of non-alcoholic fatty liver disease and its interaction with PNPLA3 variant. Journal of Gastroenterology and Hepatology 2013;28(5):873-9. doi: 10.1111/jgh.12104. (Tier 2; Impact Factor = 2.87) (ISI-Indexed)
  • Zain SM, Mohamed Z, Mahadeva S, Rampal S, Basu RC, Cheah PL, Agus S, Rosmawati Mohamed. Susceptibility and gene interaction study of the angiotensin II type 1 receptor (AGTR1) gene polymorphisms with non- alcoholic fatty liver disease in a multi- ethnic population. PLOS ONE 2013 Apr 8;8(4):e60729 (Tier 1 ISI-Cited Publication) (ISI-Indexed)
  • Zain SM, Mohamed Z, Mahadeva S, Cheah PL, Rampal S, Chin KF, Basu RC, Tan HL, Mohamed R. The impact of LEPR variants on risk of non-alcoholic fatty liver disease and its interaction with PNPLA3 variant. J Gastroenterol Hepatol ;28(5):873-9. (ISI-Indexed)
  • KP,Ng, YF Ngeow, Rozainah K, Rosmawati M. Hepatitis B seroprevalence among University of Malaya Students in the Post-universal Infant Vaccination Era. Med J Malaysia 2013:68;144-147. (SCOPUS-Indexed)
  • Chan WK, Tan SS, Rosmawati Mohamed. Stopping Therapy in HBeAg Negative Disease. Curr Hepatitis Rep DOI 10.1007/s11901-013-0167-5 (ISI-Indexed)

2012
  • Rosmawati Mohamed, Chirk J Ng, Wen T Tong, Suraya Z Abidin, Li P Wong, Wah Y Low. 2012. Knowledge, attitudes and practices among people with chronic hepatitis B attending a hepatology clinic in Malaysia: A cross sectional study. BMC Public Health 12: 601. (ISI/SCOPUS Indexed Publication)
  • Zain SM, Mohamed R, Mahadeva S, Cheah PL, Rampal S, Basu RC, Mohamed Z.A multi-ethnic study of a PNPLA3 gene variant and its association with disease severity in non-alcoholic fatty liver disease.Hum Genet. 2012 Jul;131(7):1145-52 (ISI-Indexed)
  • Kok Beng Loh, MRAD1, Shaik Ismail Bux, MRAD1, Basri Johan Jeet Abdullah, FRCR1, Raja Amin Raja Mokhtar, FRCS2, Rosmawati Mohamed, MD3 Departments of 1Biomedical Imaging, 2Surgery and 3Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia. Hemorrhagic Cardiac Tamponade: Rare Complication of Radiofrequency Ablation of Hepatocellular Carcinoma http://dx.doi.org/10.3348/kjr.2012.13.5.643 pISSN 1229- 6929 eISSN 2005-8330 Korean J Radiol 2012;13(5):643-647 (ISI-Indexed)
  • Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2012 update. Hepatology International 2012 (ISI-Indexed)

2011
  • Chirk Jenn, Ng, Low, W.Y., Wong, Y.L, Sudin, M.R., Mohamed, R. 2011. Uncovering the experiences and needs of patients with chronic Hepatitis B infection at diagnosis: A qualitative study. Asia Pac J Public Health 2011. DOI: 10.1177/101053951141258 (ISI/SCOPUS Indexed Publication)

2010
  • Prevention of hepatocellular carcinoma in the Asia- Pacific region: Consensus statements. Farrell GC, Chan HL, Yuen MF, Amarapurkar DN, Chutaputti A, Fan JG, Hou JL, Han KH, Kao JH, Lim SG, Mohamed R, Sollano J, Ueno Y. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY 2010;25 (4):657-663 (ISI-Indexed)
  • Lui YY, Tsoi KK, Wong VW, Kao J-H, Hou J-L, Teo E-K, Rosmawati M, Piratvisuth T, Han K-H, Mihm U, Wong GL, Chan HL. Cost-effectiveness analysis of roadmap models in chronic hepatitis B using tenofovir as the rescue therapy. Antiviral Therapy 2010;15:145-155 (ISI-Indexed)

2009
  • Lim SG, Mohammed R, Yuen MF, Kao JH. Prevention of hepatocellular carcinoma in hepatitis B virus infection. J Gastroenterol Hepatol. 2009 Aug;24 (8):1352-7. (ISI-Indexed)
  • Application of surveillance programs for hepatocellular carcinoma in the Asia-Pacific Region. Amarapurkar D, Han KH, Chan HL, Ueno Y; Asia-Pacific Working Party on Prevention of Hepatocellular Carcinoma. (Collaborators: Farrell GC, Chan HL, Yuen MF, Amarapurkar DN, Chutaputti A, Fan JG, Hou JL, Han KH, Kao JH, Lim SG, Mohamed R, Sollano J, Ueno Y) J Gastroenterol Hepatol. 2009 Jun;24(6):955-61. Epub 2009 Mar 11. (ISI-Indexed)
  • Hepatocellular carcinoma in the Asia pacific region. Yuen MF, Hou JL, Chutaputti A; (Collaborators: Farrell GC, Chan HL, Yuen MF, Amarapurkar DN, Chutaputti A, Fan JG, Hou JL, Han KH, Kao JH, Lim SG, Mohamed R, Sollano J, Ueno Y). Asia Pacific Working Party on Prevention of Hepatocellular Carcinoma. J Gastroenterol Hepatol. 2009 Mar;24(3):346-53. Epub 2009 Feb 12. Review (ISI-Indexed)

2006
  • Ooi A, Tan S, Rosmawati M, Rahman NA, Othman RY. The full-length clone of Cucumber Green Mottle Mosaic Virus and its application as an expression system for Hepatitis B surface antigen. Journal of Biotechnology 2006 Feb 24;121(4):471-81 (ISI-Indexed)

2005
  • Rosmawati M. Aetiology and classification of acute liver failure. Med J Malaysia 2005;60:125-6. 
  • Differential gene expression in colorectal cancer: quantitative analyses of angiogenesis genes and identification of potential candidates as molecular markers. JH Siong, AH Jennifer, SH Lim, M Rosmawati, M Sanjiv, LLC Ng, CW Law, CC Yeo. Medical Journal of Malaysia Vol. 60 Supplement A June 2005 (SCOPUS-Indexed)

2004
  • Rosmawati M, Desmond P, Dong-Jin Suh, Deepak A, Ed Gane, et al. Practical difficulties in the management of hepatitis B in the Asia-Pacific region. J Gastroenterology and Hepatology 2004;19:958-969 (ISI-Indexed)

2002
  • Rosmawati Mohamed, Freeman JW, Guest PJ, Davies MK, Neuberger JM. Pulmonary gas exchange abnormalities in liver transplant candidates. Liver Transpl 2002 Sep;8 (9):802-8 (ISI-Indexed)
  • Lai CL, Rosmawati Mohamed, Lao J, Van Vlierberghe H, Anderson FH, Thomas N, Dehertogh D. Entecavir is superior to lamivudine in reducing hepatitis B virus DNA in patients with chronic hepatitis B infection. Gastroenterology. 2002 Dec;123(6):1831-8 (ISI-Indexed)
  • Yap SF, PW Wong YC Chen, M. Rosmawati. The frequency of Pre-core gene mutations in chronic Hepatitis B infection : A study of Malaysian subjects. Southeast Asian J Trop Med Public Health 2002;33:102-109 (ISI-Indexed)

1999
  • Intrahepatic biloma: an unusual complication of cholangiocarcinoma treated endoscopically Author(s): Ranjeev, P; Goh, KL; Rosmawati, M, et al. Source: GASTROINTESTINAL ENDOSCOPY Volume: 50 Issue: 5 Pages: 711-713 Published: NOV 1999 (ISI-Indexed)

1997
  • Rosmawati Mohamed, Hubscher SG, Mirza DF, Gunson B, Mutimer DJ. Post-transplantation chronic hepatitis in fulminant hepatic failure. Hepatology 1997;25(4):1003- 1007 (ISI-Indexed)

1996
  • Rosmawati Mohamed, Goh KL, Wong NW. Primary Biliary Cirrhosis. Med J Malaysia 1996;51:99-102 (ISI/SCOPUS Indexed Publication)
  • Rosmawati Mohamed, Forsey PR, Davies MK, Neuberger JM. Effect of liver transplantation on QT interval prolongation and autonomic dysfunction in end-stage liver disease. Hepatology 1996; 23 (5):1128-1134 (ISI-Indexed)

1995
  • Mirza DF, Rosmawati Mohamed, Mutimer DJ, McMaster P. Timing and candidacy for transplantation in acute liver failure: the European experience. Liver Transplantation 1995; 1 :182-186 (ISI-Indexed)
Extended Abstract
Monograph
Technical Report

AREAS OF RESEARCH
(Project title), (Role), (From)-(Until), (Level), (Source).


  • Detection of Familial Hypercholesterolemia gene mutation amongst the Malaysian population
  • Treatment of Chronic Hepatitis B
  • 56136379HPB2001 A Phase 2a, Randomized, Partially-blind, Placebo-controlled Study to Assess the Efficacy, Safety and Pharmacokinetics of Treatment With Multiple Doses of JNJ-56136379 as Monotherapy and in Combination With a Nucleos(t)ide Analog in Subjects With Chronic Hepatitis B Virus Infection, Principal Investigator(PI), 2018 - 2019, International Funding, (International)
  • 56136379HPB1001:A Phase 1, double-blind, randomized, placebo-controlled, first-in-human study of orally administered JNJ-56136379 to evaluate safety, tolerability and pharmacokinetics after single ascending doses and one multiple dose regimen in healthy subjects (Part I), and after multiple dose regimens in subjects with chronic hepatitis B(Part II), Principal Investigator(PI), 2017 - 2018, International Funding, (International)
  • Inhibitory Receptors Pathway Blockade As A Potential Cancer Therapy, Principal Investigator(PI), 2017 - 2020, UM Grant - Frontier Research Grant, (National)
  • Genetic Determinants Of Susceptibility And Severity In Non-alcoholic Fatty Liver Disease, Consultant, 2016 - 2019, Bantuan Kecil Penyelidikan (BKP), (National)
  • Genetic Susceptibility To Liver Disease Progression In Hbv Infected Individuals, Principal Investigator(PI), 2015 - 2018, Postgraduate Research Grant (PPP) - Research, (National)
  • Emerging Concepts In Hepatitis B And Hepatitis D Viral Coinfection In Kuala Lumpur, Malaysia, Consultant, 2014 - 2017, Geran Penyelidikan Universiti Malaya (UMRG Programme) - HTM (Wellness), (University)
  • A multicenter open-label study to evaluate the safety and efficacy of PEG-IntronTM versus PEGASYSTM in subjects with HBeAg positive chronic hepatitis B and HBeAg negative chronic hepatitis B., Principal Investigator(PI), 2013 - 2016, Merck Pharmaceuticals, (National)
  • A Phase 3 Clinical Trial to Study Short Duration Versus Standard Response-Guided Therapy with MK- 3034 (SCH 503034)/ Boceprevir Combined with PegIntron and Ribavirin in Previously Untreated Non-Cirrhotic Subjects with Chronic HCV Genotype 1 in Asia, Principal Investigator(PI), 2013 - 2016, MSD Pharmaceuticals, (National)
  • Effect of coffee on viral activity and host immune response in chronic hepatitis B infection, Principal Investigator(PI), 2013 - 2015, High Impact Research (HIR), (National)
  • Effect Of Coffee On Viral Activity And Host Immune Response In Chronic Hepatitis B Infection., Principal Investigator(PI), 2013 - 2016, High Impact Research - Ministry of Education (HIR-MOE) Cycle 3, (National)
  • Genetics and Proteomics : Towards Diagnosis and Prognosis of Non-Alcoholic Fatty Liver Disease, Principal Investigator(PI), 2013 - 2016, Postgraduate Research Grant (PPP) - Research, (National)
  • Pharmacogenomics Study Of Possible Anti-obesity Agent From Catha Edulis Plant Extract And Its Main Alkaloid Cathinone On Obese Animal Model, Consultant, 2013 - 2018, Geran Penyelidikan Universiti Malaya (UMRG) - HTM (Wellness), (University)
  • Expression Patterns of Non-Alcoholic Fatty Liver Disease genes and Efficacy of Green Tea on Hyperlipidemic Animal Model, Principal Investigator(PI), 2013 - 2016, Geran Penyelidikan Universiti Malaya (UMRG) - HTM (Wellness), (University)
  • Pharmocogenomics of Adverse Drug Reactions: Focus on Anti-tuberculosis Drug Induced Liver Injury (AT-DILI)., Principal Investigator(PI), 2013 - 2015, High Impact Research - University of Malaya (HIR-UM), (National)
  • Pharmocogenomics of Adverse Drug Reactions: Focus on Anti-tuberculosis Drug Induced Liver Injury (AT-DILI). 01/07/2013 to 31/07/2015, Principal Investigator(PI), 2013 - 2015, High Impact Research (HIR), (National)
  • Mechanisms of T cell dysfunctions in hepatitis C infection, Co-Investigator, 2012 - 2014, High Impact Research (HIR), (National)
  • Perception of Complimentary and Alternative Medicine (CAM)use in Hepatitis B- A Malaysian Perspective, Co-Investigator, 2012 - 2013, Monash University Malaysia, (National)
  • Pharmacogenomic studies in Non- Alcoholic Fatty Liver Disease (NAFLD), Co-Investigator, 2011 - 2012, High Impact Research (HIR), (National)
  • NOVEL MARKERS FOR HEPATITIS B VIRUS (HBV) STRAINS ASSOCIATED WITH LIVER COMPLICATIONS IN CHRONIC HEPATITIS B PATIENT, , 2010 - 2011, Postgraduate Research Grant (PPP) - Research, (National)
  • HOST AND VIRAL FACTORS AFFECTING HBSAG LEVEL IN HEPATITIS B INFECTION, , 2010 - 2011, Postgraduate Research Grant (PPP) - Research, (National)
  • GENES INVOLVED IN NON-ALCOHOLIC FATTY LIVER DISEASE (NAFID) AND THEIR ASSOCIATION WITH CARDIOVASCULAR DISEASE IN MALAYSIAN PATIENTS, , 2010 - 2011, Postgraduate Research Grant (PPP) - Research, (National)
  • A NON-GEL BASED PROTEOMIC APPROACH IN IDENTIFYING DIFFERENTIALLY EXPRESSED PROTEINS IN COLORECTAL CANCER, , 2010 - 2011, Postgraduate Research Grant (PPP) - Research, (National)
  • VARIATION ACROSS CANDIDATE GENES AND ITS ROLE IN THE DEVELOPMENT NON- ALCOHOLIC FATTY LIVER DISEASE (NAFLD) AND ITS COMPLICATIONS IN PATIENTS WITH METABOLIC SYNDROME, Principal Investigator(PI), 2009 - 2011, Geran Penyelidikan Universiti Malaya (UMRG), (National)
  • Variation across candidate genes and its role in the development of Non-alcoholic fatty liver disease and its complications in patients with metabolic syndrome, Principal Investigator(PI), 2009 - 2011, Geran Penyelidikan Universiti Malaya (UMRG), (National)
  • A multinational, randomised, open-label, phase 3 study of sunitinib malate vs sorafenib in patients with advanced hepatocellular carcinoma., Co-Investigator, 2008 - 2011, Pfizer, (International)
  • Hepatitis B Survey: Patients Disease Profile and Their Quality of Life, Principal Investigator(PI), 2007 - 2008, Fundamental Vote, University of Malaya, Kuala Lumpur, (University)
  • Proteomic and Genomic Analysis Of Colorectal Polyps And Cancer, Principal Investigator(PI), 2007 - 2011, Geran Penyelidikan Universiti Malaya (UMRG), (National)
  • Detection of Familial Hypercholesterolemia gene mutation amongst the Malaysian population, Principal Investigator(PI), 2006 - 2012, MOSTI, (National)

CONSULTATION PROJECT/CONSULTANCY
(Project title), (Role), (From)-(Until), (Organisation).


  • Expert Working Group Meeting on Surveillance, Prevention and Management of Viral Hepatitis, 2014-2014, WHO Regional Office for the Western Pacific
  • Advisory Board Member, 2013-2013, Novartis Pharmaceuticals Corporation
  • HEPATITIS C ADVISORY BOARD, 2013-2013, Abbvie Pharmaceuticals
  • APASL 3RD STC ON HBV 2012 DHAKA, 2012-2012, ASIAN PACIFIC ASSOCIATION FOR THE STUDY OF THE LIVER
  • IMPROVING MANAGEMENT OF VIRAL HEPATITIS THROUGH BETTER PUBLIC POLICIES, 2012-2012, Coalition to Eradicate Viral Hepatitis in the Asia-pacific
  • Epidemiology of Hepatitis B in Asia-Pacific, 2012-2012, APDW Federation
  • Vertex Asia-Pacific Hepatitis Advisory Board, 2012-2012, Merck Sharp & Dohme (Asia) Ltd.
  • Asia-Pacific Hepatitis Advisory Board (MSD), 2011-2011, Merck Sharp & Dohme (Asia) Ltd.
  • External Examiner for Gastroenterology Fellowship Exit Exam, 2011-2011, Ministry of Health
  • External Examiner for B Medical Science, 2010-2010, International Medical University
  • Chronic Hepatitis B - Longterm Management Strategies, 2008-2008, Glaxo-Smith Kline
  • Chronic Hepatitis B 2008, 2008-2008, Novartis
  • Chronic Hepatitis B Guideline Working Party of the Asian-Pacific Association for the Study of the Liver, 2007-ongoing, 2007-2007, Asian-Pacific Association for the Study of the Liver
  • Asia Pacific Hepatitis B Management Advisory Board, 2002-2002, Glaxo-Smith Kline

AWARDS AND RECOGNITIONS
(Name of Award), (Awarding Institution), (Year Awarded), (Level).


  • 2nd Best Poster Award, Asian-Pacific Association for The Study of The Liver (Apasl) , 2018, (International)
  • Fellow, Academy of Medicine, Singapore, Academy of Medicine, Singapore, 2017, (International)
  • Poster of Distinction, Asian Pacific Association for The Study of The Liver, 2014, (International)
  • Khidmat Setia 20 Award, 2011
  • Travel Award, Nash2010, Ninth Japan Society of Hepatology Single Topic Conference, 2010, (International)
  • Excellence Service Award, University Malaya, 2007, (University)
  • Certificate of Excellent Service, University Malaya, 2006, (University)
  • Excellence Service Award, University Malaya, 2004, (University)

PRESENTATIONS
(Title), (Event), (Date Presented), (Organiser), (Level).


INVITED SPEAKER
  • Treating the hardest-to-cure: Treatment options for non-responders to peginterferon plus ribavirin today and in the future, Regional Expert Forum on the Liver and Kidney, Hanoi, Vietnam , 2008-06-20 to 2008-06-23, (International)
  • IMPROVING MANAGEMENT OF VIRAL HEPATITIS THROUGH BETTER PUBLIC POLICIES , Asian Pacific Association for the Study of the Liver, 2012-02-16 to 2012-02-19, (International)
  • Aiming high to cure more patients through personalized healthcare, ASIAN PACIFIC PERSPECTIVE IN HEPATITIS (APPH) 2012, 2012-06-01 to 2012-06-02, Thailand Association for the Study of Liver, (International)
  • Strategies to Optimize Response to Pegylated Interferon in HBeAg-positive Chronic Hepatitis B, APASL 3rd STC on HBV, 2012-10-07 to 2012-10-08, (International)
  • HBV management in special situations, Asian Pacific Digestive Week 2012, 2012-12-05 to 2012-12-08, (International)
  • Epidemiology and Hepatitis B in Asia-Pacific, Asian Pacific Digestive Week 2012, 2012-12-05 to 2012-12-08, (International)
  • CHRONIC VIRAL HEPATITIS B&C:WHAT IS THE LATEST GUIDELINE , 4th EAST COAST GASTRO-HEPATOLOGY CONFERENCE , 2014-04-28 to 2014-04-30, Hospital HRPZII, Kota Bharu Kelantan , (National)
  • Revisiting HCC: The 2016 evidence for preventing HCC and HCC recurrence, 4th ASEAN Perspective in Liver Diseases 2016 (APLD 2016), 2016-01-20 to 2016-01-23, Thai Association for the Study of the Liver (THASL), (International)
  • Prevention of HCC and recurrence, 8th Annual Meeting of Asia-Pacific Alliance of Liver Diseases, 2016-09-02 to 2016-09-04, 8th APALD Conference Secretariat, (International)
PLEANARY/KEYNOTE SPEAKER
  • HBV in the Asia Pacific, 16th Asia Pacific Congress of Clinical Microbiology and Infection, 2016-11-30 to 2016-12-03, APCCMI 2016 Congress Organisers, (International)
EVENT ORGANISER
  • Personalizing Medicine - The A La Carte Approach, 42nd Malaysia-Singapore Congress Of Medicine, , 2008-08-01 to 2008-08-03, Academy of Medicine, Malaysia, (International)
  • Driving Research Innovation Towards Value Creation , Pecipta 2009, 2009-10-08 to 2009-10-10, (International)
POSTER
  • DIFFERENTIALLY EXPRESSED PROTEINS IN COLORECTAL CANCER SERUM BY TWO-DIMENSIONAL GEL ELECTROPHORESIS , 5th Asean Society of Colorectal Surgeons Scientific Congress & 8th Malaysian Colorectal Conference Coloproctology 2010 , 2010-03-05 to 2010-08-06, (International)
  • A qualitative study of medical doctors' views and experiences of the use of CAM chronic hepatitis B: , Gastro2013, 2013-09-21 to 2013-09-24, World Congress of Gastroenterology. , (International)
  • WHY DO PATIENTS WITH CHRONIC HEPATITIS B USE COMPLEMENTARY AND ALTERNATIVE MEDICINE? , 23RD CONFERENCE OF THE ASIAN PACIFIC ASSOCIATION FOR THE STUDY OF THE LIVER, 2014-03-12 to 2014-03-15, ASIAN PACIFIC ASSOCIATION FOR THE STUDY OF THE LIVER, (International)
OTHERS
  • Liver biopsy for Chronic Hepatitis B, 16th Conference of the Asian Pacific Association for the Study of the Liver,MANILA, PHILLIPINES, 2006-03-05 to 2006-03-08, The Philippine Society of Gastroenterology, (International)
  • Treatment Strategies in Hepatitis B, Asian-Pacific Digestive Week, 2006-11-26 to 2006-11-29, (International)
  • Anti HCV (+) HCV RNA (+) Normal ALT: Treat or Not to Treat, Asian-Pacific Digestive Week, Cebu City , Philippines, 2006-11-27 to  , (International)
  • CONDUCTING CLINICAL TRIALS IN MALAYSIA, Bio Malaysia 2006 Conference, 2006-12-06 to 2006-12-08, Malaysian Biotechnology Corporation (BiotechCorp), the Malaysian BioIndustry Organisation (MBIO) AND MOSTI, (National)

EXPERT LINKAGES
(Linkages Description), (Organisation), (Year of Involvement), (Duration), (Level).


  • Strategic and Technical Advisory Committee for Viral Hepatitis (STAC-HEP), World Health Organization, 2018, (International)
  • Committee Member, Asia-Pacific Expert Committee on Hepatitis B Management, 2002, 60, (International)

CONTRIBUTION TO SOCIETY
(Contribution To Society), (Level), (Start Date), (End Date).


  • Raising awareness on hepatitis and liver cancer using a film, (National), 20/09/2018 until 31/12/2019
  • Raising public Awareness on Hepatitis C via "How's Your Blood" Campaign, (National), 05/07/2018 until 30/11/2018
  • Participated in the WHO "Call To Action To Scale Up Global Hepatitis Response, (International), 27/03/2014 until 28/03/2014
  • Organising Chairperson for National level hepatitis Awareness in Malaysia, (National), 10/01/2011 until  

SUPERVISION


POST GRADUATE STUDENT
(Name of Degree), (Name of Candidates), (Title of Thesis), (Academic Session)

Completed
  • Master Degree, Dr. Nor Suraya Binti Samsudin, Knowledge, attitude and practice among inflammatory bowel disease patients in UMMC, 2010/2011
  • Master Degree, Teo Ching Yee, Variations in the core promoter and precore regions of hepatitis B, 2009/2010
  • Doctoral Degree (phd), Shamsul Mohd Zain, Variation across candidate genes and its role in the development of non- alcoholic fatty liver disease and its complications in patients with metabolic syndrome, 2009/2010
  • Master Degree, Ho Ka Yen, Methylation of Hepatitis B Virus Genome In Hepatitis B Virus Associated Hepatocellular Carcinoma, 2009/2010
  • Master Degree, Mohamad Nazrulhisham Bin Mad Naser, Favorable Effect Of Extracorporeal Shock Myocardial Revascularization (ESMR) On Left Ventricular (LV) Mechanical Dyssynchrony, 2008/2009
  • Doctoral Degree (phd), Jb Chook, Novel Biomarkers for Predicting Clinical Outcomes of Chronic Hepatitis B Infection, 2008/2009
  • Master Degree, Dr. Suganthy A/p Robinson, Cardiovascular Risk Factors in HIV patients on HAART at University Malaya Medical Centre, 2006/2007
  • Doctoral Degree (phd), Ooi Aik Seng, The full-length clone of Cucumber Green Mottle Mosaic Virus and its application as an expression system for Hepatitis B surface antigen, 2004/2005
  • Master Degree, Dr. Sindhu Girish Chandran, Delirium among elderly in the medical wards of a tertiary hospital in Malaysia, 2004/2005
  • Master Degree, Dr. Shakeel Ahmed, Association between exercise stress ECG, erectile dysfunction and cardiovascular risk factors, 2003/2004
  • Master Degree, Dr. Chua Chin Jou, Hepatitis B and C Infection in Patients With Endstage Renal Disease On Renal Replacement Therapy, 1998/1999
  • Master Degree, Dr Anil Radhakrishnan, Validation Of A New Rapid Hepatitis B Test For The Detection Of Surface and e Antigens in Whole Blood, 1997/1998
  • Master Degree, Dr Asmah Mohd, The association between HLA genes and radiological disease severity in Malaysian patients with Rheumatoid Arthritis at University Malaya Medical Centre, 1997/1998

Ongoing
  • Doctoral Degree (phd), Behnaz Riazalhosseini, GENETIC SUSCEPTIBILITY TO LIVER DISEASE PROGRESSION IN HBV INFECTED INDIVIDUALS, 2012/2013
  • Doctoral Degree (phd), Tan Hwa Li, Genetics and Proteomics : Towards Diagnosis and Prognosis of Non-Alcoholic Fatty Liver Disease, 2011/2012
  • Master Degree, Choong Poh Yee, Comparative Proteomic Analysis Of Corresponding Colon Cancer Plasma And Tissue Samples By Lc-Maldi Tandem Mass Spectrometry, 2010/2011
  • Master Degree, Lye Say Hean, Genetic polymorphisms in LDLR, APOB, PCSK9 and other lipid related genes associated with Familial Hypercholesterolemia, 2010/2011
  • Master Degree, Mihat Munirah, Identification of proteins that are differentially expressed in the serum of patients with colorectal cancer, 2008/2009

TEACHING
(Course Title), (Academic Session), (No of Student), (No of Contact Hours).


POST GRADUATE
  • SARJANA PERUBATAN DALAMAN, 2018/2019, 20, 240
  • Internal Medicine, 2014/2015, 10, 100
  • Masters in Internal Medicine, 2012/2013, 36, 150
FIRST DEGREE
  • UMMP, 2018/2019, 60, 32
  • Phase 3B, 2014/2015, 10, 8
  • Phase 3B, 2013/2014, 191, 1
  • Phase 3A, 2013/2014, 40, 4
  • Phase 2, 2013/2014, 8, 3
  • Phase 3B, 2012/2013, 204, 73
  • BDS, 2007/2008, 84, 1