Curriculum Vitae

PERSONAL DETAILS

PROF. DR. MOHD RAIS BIN MUSTAFA

  • Honorary Professor

  • Department of Pharmacology
    Faculty of Medicine
  •    +603-79674952
  •   rais@um.edu.my

ADMINISTRATIVE DUTIES
(Role),(Level),(Duration)
  • Deputy Dean of Research, UNIVERISITI MALAYA, 01/08/2014 to 31/07/2016
  • Head of CENAR (Centre For Natural Product And Drug Discovery), University Malaya, 01/01/2015 to 31/12/2016
  • Head, UNIVERISITI MALAYA, 01/01/2015 to 31/12/2015
  • Deputy Dean of Research, UNIVERISITI MALAYA, 01/07/2014 to 31/07/2014
  • Deputy Dean of Research, UNIVERISITI MALAYA, 01/02/2014 to 30/06/2014
  • Research Cluster Dean, UNIVERISITI MALAYA, 03/01/2012 to 31/12/2012
  • Research Cluster Dean, UNIVERISITI MALAYA, 01/01/2011 to 31/12/2011
  • Deputy Dean, UNIVERISITI MALAYA, 01/11/2009 to 30/06/2011
  • Research Cluster Dean, UNIVERISITI MALAYA, 01/01/2010 to 31/12/2010
  • Deputy Dean, UNIVERISITI MALAYA, 01/09/2009 to 31/10/2009
  • Research Cluster Dean, UNIVERISITI MALAYA, 01/01/2009 to 31/12/2009
  • Head of Department, UNIVERISITI MALAYA, 01/09/2008 to 31/08/2009
  • Head of Department, UNIVERISITI MALAYA, 01/09/2007 to 31/08/2008
ACADEMIC QUALIFICATION
(Qualification),(Field),(Institution),(Year)
  • PHD, LAIN-LAIN, UNIVERSITY OF WALES, INSTITUTE OF SCI. & TECHNICAL
  • BSC, PHILOSOPHY, UNIVERSITY OF WALES INSTITUTE, CARDIFF, UK
MEMBERSHIPS
(Organisation),(Role),(Duration),(Level)
  • Jawatankuasa Makmal Fakulti Perubatan, Oridinary Member,  (University)
  • British Pharmacological Society, Member, 2009 to 2018 (International)
SPECIALIZATION
(Area)
Area of Expertise
  • (Angiotensin II, Des-Aspartate Angiotensin I, Angiotensin 1-7)
  • (Endothelial dysfunctions in diabetes, cancer, ageing and cardiovascular associated disorders)
  • TRADITIONAL MEDICINE AND NATURAL PRODUCT (Flavonoids (Quercetin), Traditional Chinese Medicine, Boldine, Paeonol, Labisia Pumila, Apocynum Venetum, Hibiscus Sabdariffa)
  • Research Interest
  • Natural Products and Drug Discovery
  • Novel Angiotensin peptides
  • Endothelial dysfunctions
  • Flavonoids (Quercetin, baicalein, )
  • Oxidative stress (Superoxides, NADPH, antioxidants)
  • TEACHING
    (Course Title),(Level of Study),(Institution),(Academic Session)
    Teaching
  • MBBS - Medical Pharmacology, First Degree, UNIVERSITY MALAYA (2011/2012)
  • BDS - Dental Pharmacology, First Degree, UNIVERSITY MALAYA (2011/2012)
  • MBDS - Master Dental Pharmacology, Post Graduate, UNIVERSITY MALAYA (2011/2012)
  • MBBS - Medical Pharmacology, First Degree, UNIVERSITY MALAYA (2011/2012)
  • Dental Pharmacology (Bds), First Degree, UNIVERSITY MALAYA (2015/2016)
  • UMMP - Medical Pharmacology, First Degree, UNIVERSITY MALAYA (2013/2014)
  • BDS - Dental Pharmacology, First Degree, UNIVERSITY MALAYA (2013/2014)
  • MWEF1108 - Principles of Drug Action & Peripheral Nervous System, First Degree, UNIVERSITY MALAYA (2013/2014)
  • MWEF2103 - Central Nervous System & Therapy, First Degree, UNIVERSITY MALAYA (2013/2014)
  • BDS - Dental Pharmacology, First Degree, UNIVERSITY MALAYA (2014/2015)
  • UMMP - Medical Pharmacology, First Degree, UNIVERSITY MALAYA (2014/2015)
  • MBDS - Master Dental Pharmacology, Post Graduate, UNIVERSITY MALAYA (2010/2011)
  • BDS - Dental Pharmacology, First Degree, UNIVERSITY MALAYA (2012/2013)
  • BDS - Dental Pharmacology, First Degree, UNIVERSITY MALAYA (2012/2013)
  • MDEB3401 - Advanced Medical Pharmacology, First Degree, UNIVERSITY MALAYA (2012/2013)
  • MDEB3401 - Advanced Medical Pharmacology, First Degree, UNIVERSITY MALAYA (2010/2011)
  • Medical Pharmacology (Ummp), First Degree, UNIVERSITY MALAYA (2015/2016)
  • MWEF2103 - Central Nervous System & Therapy, First Degree, UNIVERSITY MALAYA (2010/2011)
  • MWEF1108 - Principles of Drug Action & Peripheral Nervous System, First Degree, UNIVERSITY MALAYA (2010/2011)
  • PUBLICATIONS
    (Title of publication in APA style)
    Refereed Journals
    2020
    • Therapeutic Implications of Nitrite in Hypertension WC Ling, MR Mustafa, DD Murugan Journal of Cardiovascular Pharmacology 75 (2), 123-134 (ISI-Indexed)
    • Vernodalin induces apoptosis through the activation of ROS/JNK pathway in human colon cancer cells N Mohebali, AK Pandurangan, MR Mustafa, SK Anandasadagopan, ... Journal of Biochemical and Molecular Toxicology, e22587 (ISI-Indexed)
    2018
    • Autophagy through stress-activated signals: a cellular self-defence mechanism against MBIC in human breast cancer cell-lines. Mohadeseh Hasanpourghadi, Nazia Abdul Majid, Mohd Rais Mustafa. Biochemical Pharmacology. doi: 10.1016/j.bcp.2018.03.030 (ISI-Indexed)
    • Tong KL, Mahmood Zuhdi AS, Wan Ahmad WA, Vanhoutte PM, de Magalhaes JP, Mustafa MR and Wong PF. Circulating MicroRNAs in Young Patients with Acute Coronary Syndrome. Int. J. Mol. Sci. 2018, 19, 1467; doi:10.3390/ijms19051467 (ISI-Indexed)
    • Lai SL, Mustafa MR, Wong PF. Panduratin A induces protective autophagy in melanoma via the AMPK and mTOR pathway. Phytomedicine. 2018 Mar 15;42:144-151. doi: 10.1016/j.phymed.2018.03.027 (ISI-Indexed)
    • Choy KW, Murugan D, Mustafa MR. (2018). Natural products targeting ER stress pathway for the treatment of cardiovascular diseases. Pharmacol. Res, 132, 119-129 (ISI-Indexed)
    • Ling, W. C., Mustafa, M. R., Vanhoutte, P. M., & Murugan, D. D. (2018). Chronic administration of sodium nitrite prevents hypertension and protects arterial endothelial function by reducing oxidative stress in angiotensin II-infused mice. Vascular Pharmacology, 102, 11-20. (ISI-Indexed)
    • Choy, K. W., Lau, Y. S., Murugan, D., Vanhoutte, P. M., & Mustafa, M. R. (2018). Paeonol Attenuates LPS-Induced Endothelial Dysfunction and Apoptosis by Inhibiting BMP4 and TLR4 Signaling Simultaneously but Independently. Journal of Pharmacology and Experimental Therapeutics, 364(3), 420-432. (ISI-Indexed)
    • Lau, Y. S., Mustafa, M. R., Choy, K. W., Chan, S. M. H., Potocnik, S., Herbert, T. P., et al. (2018). 3 ',4 '-dihydroxyflavonol ameliorates endoplasmic reticulum stress-induced apoptosis and endothelial dysfunction in mice. Scientific Reports, 8.1818 (ISI-Indexed)
    • Hasanpourghadi, M., Pandurangan, A. K., & Mustafa, M. R. (2018). Modulation of oncogenic transcription factors by bioactive natural products in breast cancer. Pharmacological Research, 128, 376-388. (ISI-Indexed)
    • Hasanpourghadi M, Abdul Majid N, Rais Mustafa M (2018). The role of miRNAs 34a, 146a, 320a and 542 in the synergistic anticancer effects of methyl 2-(5-fluoro-2-hydroxyphenyl)-1H- benzo[d]imidazole-5-carboxylate (MBIC) with doxorubicin in breast cancer cells. PeerJ 6:e5577 https://doi.org/10.7717/peerj.5577 (ISI-Indexed)
    2017
    • Wei Chih Ling, Mohd Rais Mustafa, Paul M Vanhoutte, Dharmani Devi Murugan. (2017). Chronic administration of sodium nitrite prevents hypertension and protects arterial endothelial function by reducing oxidative stress in angiotensin II-infused mice. Vascul Pharmacol. 2017 May 26. pii: S1537-1891(16)30268-3 (ISI-Indexed)
    • Wong PF, Jamal J, Tong KL, Khor ES, Yeap CE, Jong HL, Lee ST, Mustafa MR, Abubakar S (2017). Deregulation of hsa-miR-20b expression in TNF-alpha-induced premature senescence of human pulmonary microvascular endothelial cells. Microvascular Research 2017; 114:26-33. https://doi.org/10.1016/j.mvr.2017.06.002 (ISI-Indexed)
    • Kunasegaran T, Mustafa MR, Achike FI, Murugan DD. (2017). Quercetin and pioglitazone synergistically reverse endothelial dysfunction in isolated aorta from fructose-streptozotocin (F-STZ)-induced diabetic rats.Eur J Pharmacol. 2017 Mar 15;799:160-170 (ISI-Indexed)
    • Ling WC, Liu J, Lau CW, Murugan DD, Mustafa MR, Huang Y. (2017).Treatment with salvianolic acid B restores endothelial function in angiotensin II-induced hypertensive mice. Biochem Pharmacol. 2017 Jul 15;136:76-85. (ISI-Indexed)
    • Choy KW, Lau YS, Murugan D, Mustafa MR (2017) Chronic treatment with paeonol improves endothelial function in mice through inhibition of endoplasmic reticulum stress- mediated oxidative stress. PLoS ONE 12(5): e0178365. https://doi.org/10.1371/journal. pone.0178365 (ISI-Indexed)
    • Oncotarget. 2017 Apr 25; 8(17): 28840 28853. Published online 2017 Mar 16. doi: 10.18632/oncotarget.16263 (ISI-Indexed)
    • Hasanpourghad, M et al., (2017). Phytometabolites Targeting the Warburg Effect in Cancer Cells: A Mechanistic ReviewCurrent Drug Targets Volume: 18 Issue: 9 Pages: 1086-1094 (ISI-Indexed)
    2016
    • Ling WC, Murugan DD, Lau YS, Vanhoutte PM, Mustafa MR. (2016). Sodium nitrite exerts an antihypertensive effect and improves endothelial function through activation of eNOS in the SHR. Sci Rep. 2016 Sep 12;6:33048 (ISI-Indexed)
    • Leong KH, Looi CY, Loong X-M, Cheah FK, Supratman U, Litaudon M , Mustafa MR, Awang K (2016) Cycloart-24-ene-26-ol-3-one, a new cycloartane isolated from leaves of Aglaia exima triggers tumour necrosis factor-receptor 1-mediated caspase-dependent apoptosis in colon cancer cell line. PLoS One. (ISI-Indexed)
    • Leong KH, Looi CY, Loong XM, Cheah FK, Supratman U, Litaudon M, Mustafa MR, Awang K. 2016. Cycloart-24-ene-26-ol-3-one, a New Cycloartane Isolated from Leaves of Aglaia exima Triggers Tumour Necrosis Factor-Receptor 1-Mediated Caspase-Dependent Apoptosis in Colon Cancer Cell Line. PLoS One. 2016 Apr 12;11(4):e0152652. doi: (ISI-Indexed)
    • Kunasegaran T, Mustafa MR, Murugan DD, Achike FI. 2016. The bioflavonoid quercetin synergises with PPAR- agonist pioglitazone in reducing angiotensin-II contractile effect in fructose-streptozotocin induced diabetic rats. Biochimie. 2016 Jun;125:131-9. (ISI-Indexed)
    • Pandurangan AK, Mohebali N, Hasanpourghadi M, Looi CY, Mustafa MR, Mohd Esa N. 2016. Boldine suppresses dextran sulfate sodium-induced mouse experimental colitis: NF- B and IL-6/STAT3 as potential targets. Biofactors. 2016 May;42(3):247-58. (ISI-Indexed)
    • Shanmugam MK, Lee JH, Chai EZ, Kanchi MM, Kar S, Arfuso F, Dharmarajan A, Kumar AP, Ramar PS, Looi CY, Mustafa MR, Tergaonkar V, Bishayee A, Ahn KS, Sethi G. 2016.Cancer prevention and therapy through the modulation of transcription factors by bioactive natural compounds. Semin Cancer Biol. 2016 Mar 30. pii: S1044-579X(16)30009-8. (ISI-Indexed)
    • Choy KW, Mustafa MR, Lau YS, Liu J, Murugan D, Lau CW, Wang L, Zhao L, Huang Y. 2016.Paeonol protects against endoplasmic reticulum stress-induced endothelial dysfunction via AMPK/PPAR signaling pathway. Biochem Pharmacol. 2016 Sep 15;116:51-62. (ISI-Indexed)
    • Hasanpourghadi M, Karthikeyan C, Pandurangan AK, Looi CY, Trivedi P, Kobayashi K, Tanaka K, Wong WF, Mustafa MR. 2016. Targeting of tubulin polymerization and induction of mitotic blockage by Methyl 2-(5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) in human cervical cancer HeLa cell. J Exp Clin Cancer Res. 2016 Mar 31;35:58. (ISI-Indexed)
    2015
    • Lau Y.S., Ling, W.C, Murugan D, Kwan C.Y. and M.R. Mustafa, 2015. Endothelium-Dependent Relaxation Effect of Apocynum venetum Leaf Extract via Src/PI3K/Akt Signalling Pathway. Nutrients 2015, 7, 5239-5253; doi:10.3390/nu7075220 (ISI-Indexed)
    • Venoos Iman, Hamed Karimian, Syam Mohan, Yahya Hasan Hobani, Mohamed Ibrahim Noordin, Mohd Rais Mustafa and Suzita Mohd Noor. 2015. In vitro and in vivo anti- angiogenic activity of girinimbine isolated from Murraya koenigii. Drug Design, Development and Therapy. (ISI-Indexed)
    • Saadatdoust Z, Pandurangan AK, Ananda Sadagopan SK, Mohd Esa N, Ismail A, Mustafa MR. 2015. Dietary cocoa inhibits colitis associated cancer: a crucial involvement of the IL-6/STAT3 pathway. J Nutr Biochem. 2015 Dec;26(12):1547-58 (ISI-Indexed)
    • Arya A, Al-Obaidi MM, Karim RB, Taha H, Khan AK, Shahid N, Sayem AS, Looi CY, Mustafa MR, Mohd MA, Ali HM. 2015. Extract of Woodfordia fruticosa flowers ameliorates hyperglycemia, oxidative stress and improves -cell function in streptozotocin-nicotinamide induced diabetic rats. J Ethnopharmacol. 2015 Dec 4;175:229-40 (ISI-Indexed)
    • Ananda Sadagopan SK, Mohebali N, Looi CY, Hasanpourghadi M, Pandurangan AK, Arya A, Karimian H, Mustafa MR. 2015. Forkhead Box Transcription Factor (FOXO3a) mediates the cytotoxic effect of vernodalin in vitro and inhibits the breast tumor growth in vivo. J Exp Clin Cancer Res. 2015 Dec 8;34:147 (ISI-Indexed)
    2014
    • Shawish HB, Paydar M, Looi CY, Wong YL, Movahed E, Halim SNA, et al. Nickel (II) complexes of polyhydroxybenzaldehyde N4-thiosemicarbazones: synthesis, structural characterization and antimicrobial activities. Transition Metal Chemistry. 2014;39(1):81-94. (ISI-Indexed)
    • Rusmili MRA, Yee TT, Mustafa MR, Othman I, Hodgson WC. In-vitro Neurotoxicity of Two Malaysian Krait Species (Bungarus candidus and Bungarus fasciatus) Venoms: Neutralization by Monovalent and Polyvalent Antivenoms from Thailand. Toxins. 2014;6(3):1036-48. (ISI-Indexed)
    • Liew SY, Looi CY, Paydar M, Cheah FK, Leong KH, Wong WF, et al. Subditine, a New Monoterpenoid Indole Alkaloid from Bark of Nauclea subdita (Korth.) Steud. Induces Apoptosis in Human Prostate Cancer Cells. PloS one. 2014;9(2):e87286. (ISI-Indexed)
    • Rusmili MRA, Yee TT, Mustafa MR, Othman I, Hodgson WC. Isolation and characterization of α-elapitoxin-Bf1b, a postsynaptic neurotoxin from Malaysian< i> Bungarus fasciatus venom. Biochemical pharmacology. 2014 Mar 15;88(2):229 36. (ISI-Indexed)
    2013
    • Leong X-F, Rais Mustafa M, Jaarin K. Nigella sativa and Its Protective Role in Oxidative Stress and Hypertension. Evidence-Based Complementary and Alternative Medicine. 2013 Jan;2013. (ISI-Indexed)
    • Jong HL, Mustafa MR, Vanhoutte PM, AbuBakar S, Wong PF. 2013. MicroRNA 299-3p modulates replicative senescence in endothelial cells.Physiol Genomics. 2013 Apr 1;45(7):256-67. doi:10.1152/physiolgenomics.00071.2012 (ISI-Indexed)
    • Gummadi VR, Rajagopalan S, Looi CY, Paydar M, Renukappa GA, Ainan BR, Krishnamurthy NR, Panigrahi SK, Mahasweta K, Raghuramachandran S, Rajappa M, Ramanathan A, Lakshminarasimhan A, Ramachandra M, Wong PF, Mustafa MR, Nanduri S, Hosahalli S. Discovery of 7-azaindole based anaplastic lymphoma kinase (ALK) inhibitors: Wild type and mutant (L1196M) active compounds with unique binding mode. Bioorg Med Chem Lett. 2013 Sep 1;23(17):4911-8. doi: 10.1016/j.bmcl.2013.06.071. (ISI-Indexed)
    • Cheah S-C, Lai S-L, Lee S-T, Hadi AHA, Mustafa MR. Panduratin A, a Possible Inhibitor in Metastasized A549 Cells through Inhibition of NF-Kappa B Translocation and Chemoinvasion. Molecules. 2013;18(8):8764-78. (ISI-Indexed)
    • Arya A, Looi CY, Wong WF, Noordin MI, Nyamathulla S, Mustafa MR, et al. In vitro Antioxidant, PTP-1B Inhibitory Effects and in vivo Hypoglycemic Potential of Selected Medicinal Plants. Int J Pharmacol. 2013 Jan;9(1):50-7. (ISI-Indexed)
    • Looi CY, Moharram B, Paydar M, Wong YL, Leong KH, Mohamad K, et al. Induction of apoptosis in melanoma A375 cells by a chloroform fraction of Centratherum anthelminticum (L.) seeds involves NF-kappaB, p53 and Bcl-2-controlled mitochondrial signaling pathways. BMC complementary and alternative medicine. 2013 July 10;13(1):166. (ISI-Indexed)
    • Syam Mohan, Siddig Ibrahim Abdelwahab, Shiau-Chuen Cheah, Mohd Aspollah Sukari, Suvitha Syam, Noorasyikin Shamsuddin, et al. Apoptosis Effect of Girinimbine Isolated from Murraya koenigii on Lung Cancer Cells In Vitro. Evidence-Based Complementary and Alternative Medicine. 2013 Feb 12;2013. (ISI-Indexed)
    • Lee ST, Wong PF, He H, Hooper JD, Mustafa MR. 2013. Alpha-tomatine synergises with paclitaxel to enhance apoptosis of androgen-independent human prostate cancer PC-3 cells in vitro and in vivo. Phytomedicine. 2013 Aug 3. doi:pii: S0944-7113(13)00246-8. 10.1016/j.phymed.2013.07.002. (ISI-Indexed)
    • Looi CY, Arya A, Cheah FK, Muharram B, Leong KH, Mohamad K, et al. Induction of Apoptosis in Human Breast Cancer Cells via Caspase Pathway by Vernodalin Isolated from Centratherum anthelminticum (L.) Seeds. PloS one. 2013;8(2):e56643. (ISI-Indexed)
    • Tiong SH, Looi CY, Hazni H, Arya A, Paydar M, Wong WF, et al. Antidiabetic and Antioxidant Properties of Alkaloids from Catharanthus roseus (L.) G. Don. Molecules. 2013 Aug 15;18(8):9770-84. (ISI-Indexed)
    • Lau YS, Tian XY, Mustafa MR, Murugan D, Liu J, Zhang Y, et al. Boldine improves endothelial function in diabetic db/db mice through inhibition of angiotensin II‐mediated BMP4‐oxidative stress cascade. British journal of pharmacology. 2013;170(6):1190-8. (ISI-Indexed)
    • Lee ST, Wong PF, He H, Hooper JD, Mustafa MR. 2013. Alpha-tomatine attenuation of in vivo growth of subcutaneous and orthotopic xenograft tumors of human prostate carcinoma PC-3 cells is accompanied by inactivation of nuclear factor-kappa B signaling. PLoS One. 2013;8(2):e57708. (ISI-Indexed)
    • Yeh Siang Lau, Xiao Yu Tian, Mohd Rais Mustafa, Dharmani Murugan, Jian Liu, Yang Zhang, Chi Wai Lau, Yu Huang i, Boldine improves endothelial function in diabetic db/db mice through inhibition of angiotensin II-mediated BMP4-oxidative stress cascade.08/2013; 5.07 Impact Factor (ISI-Indexed)
    2012
    • Zandi, K., Lani, R., Wong, P.F., Teoh, B.T., Sam, S.S., Johari, J., Mustafa, M.R., AbuBakar, S. 2012. Flavone enhances dengue virus type-2 (NGC strain) infectivity and replication in vero cells. Molecules. 17(3):2437-45 (ISI-Indexed)
    • Johari, J., Kianmehr, A., Mustafa, M.R., AbuBakar, S., & Zandi, K. 2012. Antiviral activity of baicalein and quercetin against Japanese encephalitis virus. International Journal of Molecular Sciences. 13(12):16785-95 (ISI-Indexed)
    • Johari, J., Kianmehr, A., Mustafa, M.R., AbuBakar, S., & Zandi, K. 2012. Antiviral activity of baicalein and quercetin against Japanese encephalitis virus. International Journal of Molecular Science. 13(12): 16785-95 (ISI-Indexed)
    • Arbab IA, Looi CY, Abdul AB, Cheah FK, Wong WF, Sukari MA, et al. Dentatin Induces Apoptosis in Prostate Cancer Cells via Bcl-2, Bcl-xL, Survivin Downregulation, Caspase-9,-3/7 Activation, and NF-κB Inhibition. Evidence-Based Complementary and Alternative Medicine. 2012;2012. (ISI-Indexed)
    • Lau YS, Tian XY, Huang Y, Murugan D, Achike FI, Mustafa MR. Boldine protects endothelial function in hyperglycemia-induced oxidative stress through an antioxidant mechanism. Biochemical pharmacology. 2012 Feb 1;85(3):367-75. (ISI-Indexed)
    • Yeh-Siang L, Ajay M, Achike FI, Murugan D, Mustafa MR. The aporphine alkaloid boldine improves endothelial function in spontaneously hypertensive rats. Experimental Biology and Medicine. 2012;237(1):93-8 (ISI-Indexed)
    • Zandi, K., Lani, R., Wong, P.F.,Teoh, B.T., Sam, S.S., Johari, J., Mustafa, M.R., AbuBakar, S.Flavone Enhances Dengue Virus Type-2 (NGC Strain) Infectivity and Replication in Vero Cells. Molecules. 2012;17(3):2437-45. (ISI-Indexed)
    • Arya, A., Achoui, M., Cheah, S. C., Abdelwahab, S. I., Narrima, P., Mohan, S., Mustafa, M. R., Mohd, M. A. Chloroform Fraction of Centratherum anthelminticum (L.) Seed Inhibits Tumor Necrosis Factor Alpha and Exhibits Pleotropic Bioactivities: Inhibitory Role in Human Tumor Cells. Evidence-Based Complementary and Alternative Medicine. 2012;2012. (ISI-Indexed)
    • Aditya Arya, Shiau Chuen Cheah, Chung Yeng Looi, Hairin Taha, Mohd. Rais Mustafa and Mustafa Ali Mohd. 2012.The methanolic fraction of Centratherum anthelminticum seed downregulates pro-inflammatory cytokines, oxidative stress, and hyperglycemia in STZ-nicotinamide-induced type 2 diabetic rats. Food and Chemical Toxicology (Impact factor 2.99). 2012 Nov;50(11):4209-20 (ISI/SCOPUS Indexed Publication)
    • Aditya Arya, Chung Yeng Looi, Shiau Chuen Cheah, Mohd Rais Mustafa and Mustafa Ali Mohd. 2012. Anti-diabetic effects of Centratherum anthelminticum seeds methanolic fraction on pancreatic cells, β-TC6 and its alleviating role in type 2 diabetic rats. Journal of Ethnopharmacology. 2012 Oct 31;144(1):22-32.(Impact factor 3.014) (ISI/SCOPUS Indexed Publication)
    • Abdelwahab, S.I., W.S. Koko, M.M.E. Taha, S. Mohan, M. Achoui, M.A. Abdulla, M.R. Mustafa, S. Ahmad, M.I. Noordin, and C.L. Yong.In vitro and in vivo anti-inflammatory activities of columbin through the inhibition of cycloxygenase-2 and nitric oxide but not the suppression of NF- B translocation. European journal of pharmacology. 2011;678(2012):61-70. (ISI-Indexed)
    • Tan PJ, Appleton DR, Mustafa MR, Lee HB. Rapid Identification of Cyclic Tetrapyrrolic Photosensitisers for Photodynamic Therapy Using On-line Hyphenated LC-PDA- MS Coupled with Photo-cytotoxicity Assay. Phytochemical Analysis. 2011;23(1):52-9. (ISI-Indexed)
    • Zandi K, Teoh BT, Sam SS, Wong PF, Mustafa MR and AbuBakar S. 2012. Novel antiviral activity of baicalein against dengue virus. BMC Complementary and Alternative Medicine, 12:214 doi:10.1186/1472-6882-12- 214, Published: 9 November 2012 (ISI-Indexed)
    • Lai SL, Cheah SC, Wong PF, Noor SM and Mustafa MR. 2012. In vitro and In vivo Anti-angiogenic Actvities of Panduratin A. PLoS One. 2012;7(5):e38103. (ISI-Indexed)
    • Siddig Ibrahim Abdelwahab, Abdelwahab Hassan Mohamed, Osama Yousif Mohamed, Majhbob Oall, Manal Mohamed Elhassan Taha, Syam Mohan, Mohamed Ibrahim Noordin, Mohd Rias Mustafa and Khalid M. Alkharfy. Erectogenic effects of Clerodendron capitatum: involvement of phosphodiesterase type-5 inhibition. Evidence-Based Complementary and Alternative Medicine. Volume 2012 (2012), Article ID 137386, 6 pages (ISI/SCOPUS Indexed Publication)
    • Sook Yee Liew, Mat Ropi Mukhtar, A. Hamid A. Hadi, Khalijah Awang, Mohd Rais Mustafa, Kazumasa Zaima, Hiroshi Morita and Marc Litaudon, Naucline, a New Indole Alkaloid from the Bark of Nauclea officinalis, Molecules 2012, 17, 4028-4036 (ISI/SCOPUS Indexed Publication)
    2011
    • Zandi K, Teoh BT, Sam SS, Wong PF, Mustafa MR, AbuBakar S. In vitro antiviral activity of Fisetin, Rutin and Naringenin against Dengue virus Type-2. Journal of Medicinal Plants Research (2011) Vol. 5 (23), pp. 5534-5539. (ISI-Indexed)
    • Shiau-Chuen Cheah, David R. Appleton, Sui-Ting Lee , May-Lynn Lam ,A. Hamid A. Hadi and Mohd. Rais Mustafa,Panduratin A Inhibits the Growth of A549 Cells through Induction of Apoptosis and Inhibition of NF- KappaB Translocation,Molecules 2011, 16, 2583-2598 (ISI-Indexed)
    • Chong YM, Yin WF, Ho CY, Mustafa MR, Hadi AHA, Awang K, et al. 2011. Malabaricone C from Myristica Cinnamomea Exhibits Anti-Quorum Sensing Activity. Journal of Natural Products.74(10):2261-4. (ISI-Indexed)
    • Khan, H., I. Ali, A.U. Khan, M. Ahmed, Z. Shah, A. Saeed, R. Naz, M.R. Mustafa, and A. Abbasi. Purification and Biochemical Characterization of Alkaline Serine Protease from Caesalpinia Bonducella. Natural Product Communication. 2011; 5(6):931-4. (ISI-Indexed)
    • Lau Yeh-Siang , Gopal Subramaniam , A. Hamid A. Hadi , Dharmani Murugan and Mohd Rais Mustafa, Reactive Oxygen Species-Induced Impairment of Endothelium-Dependent Relaxations in Rat Aortic Rings: Protection by Methanolic Extracts of Phoebe grandis, Molecules 2011, 16(4), 2990-3000 (ISI-Indexed)
    • Aloysuis, U. I., Achike, F. I., Mustafa, M. R. 2011. Mechanisms underlining gender differences in Phenylephrine contraction of normoglycaemic and short-term Streptozotocin-induced diabetic WKY rat aorta. Vascular Pharmacology. (ISI-Indexed)
    • Jaarin K, Mustafa MR, Leong XF. The effects of heated vegetable oils on blood pressure in rats. Clinics. 2011;66(12):2125-32. (ISI-Indexed)
    • Lee ST, Wong PF, Cheah SC, Mustafa MR. Alpha-tomatine induces apoptosis and inhibits nuclear factor-kappa B activation on human prostatic adenocarcinoma PC-3 cells. PLoS One. 2011;6(4):e18915 (ISI-Indexed)
    • Leong XF, Salimon J, Mustafa MR, Jaarin K. Effect of Repeatedly Heated Palm Olein on Blood Pressure Regulating Enzymes Activity and Lipid Peroxidation in Rats. 2011. (ISI-Indexed)
    • Liew SY, Mukhtar MR, Awang K, Mustafa MR, Ng SW. 1-(1- Hydroxyethyl)-7, 8-dihydroindolo [2, 3-a] pyridine [3, 4- g] quinolizin-5 (13H)-one (angustoline) monohydrate from Nauclea subdita (Rubiaceae). Acta Crystallographica Section E: Structure Reports Online. 2011;67(7):o1727-o8 (ISI-Indexed)
    2010
    • MUHARIS, SP; TOP, AGM; MURUGAN, D; MUSTAFA, MR. 2010. Palm oil tocotrienol fractions restore endothelium dependent relaxation in aortic rings of streptozotocin- induced diabetic and spontaneously hypertensive rats. Nutrition Research, 30: 209-216 (ISI-Indexed)
    • 2010: Leong Xin-Fang; Mustafa Mohd Rais; Das Srijit; Jaarin Kamsiah Association of elevated blood pressure and impaired vasorelaxation in experimental Sprague-Dawley rats fed with heated vegetable oil. Lipids in health and disease 2010;9():66. (ISI-Indexed)
    • Mouna Achoui; David Appleton; Mahmood Ameen Abdulla; Khalijah Awang; Mustafa Ali Mohd; Mohd Rais Mustafa. (2010). In Vitro and In Vivo Anti-inflammatory Activity of 17-O-Acetylacuminolide through the Inhibition of Cytokines, NF- Translocation and IKK ctivity. Plos ONE, PONE-D-10-02204 (ISI-Indexed)
    • Kassim Mustafa; Achoui Mouna; Mustafa Mohd Rais; Mohd Mustafa Ali; Yusoff Kamaruddin Mohd Ellagic acid, phenolic acids, and flavonoids in Malaysian honey extracts demonstrate in vitro anti- inflammatory activity. Nutrition research (New York, N.Y.) 2010;30(9):650-9 (ISI-Indexed)
    2009
    • Leong XF, Najib MN, Das S, Mustafa MR, Jaarin K. 2009. Intake of repeatedly heated palm oil causes elevation in blood pressure with impaired vasorelaxation in rats. Tohoku J Exp Med.,Sep;219(1):71-8. (ISI-Indexed)
    • Chung LY, Lo MW, Mustafa MR, Goh SH, and Imiyabir Z (2009). 5-Hydroxytryptamine(2A) receptor binding activity of compounds from Litsea sessilis. Phytotherapy research : 23(3) 330-4, (ISI-Indexed)
    • Subramaniam G, Achike FI, Mustafa MR. Effect of acidosis on the mechanism(s) of insulin-induced vasorelaxation in normal Wistar- Kyoto (WKY) rat aorta. Regul Pept. 2009 Apr 10 (ISI-Indexed)
    • LY Chung, WK Soo, MR Mustafa, SH Goh, Z Imiyabir, "5- Hydroxytryptamine1A receptor binding activity of bisbenzyltetrahydroisoquinoline alkaloids from Popowia odoardoi", 2009, Pharm Biol, (ISI/SCOPUS Indexed Publication)
    • LY Chung, WK Soo, KY Chan, MR Mustafa, SH Goh, Z Imiyabir "Lipoxygenase inhibiting activity of some Malaysian plants", 2009, Pharm Biol, (ISI/SCOPUS Indexed Publication)
    • 2009: Subramaniam G; Achike Francis I; Mustafa M R Characterizing the mechanisms of insulin vasodilatation of normal and streptozotocin-induced diabetic rat aorta. Journal of cardiovascular pharmacology 2009;53(4):333-40. (ISI-Indexed)
    2008
    • Chung LY, Yap KF, Goh SH, Mustafa MR, and Imiyabir Z (2008). Muscarinic receptor binding activity of polyoxygenated flavones from Melicope subunifoliolata. Phytochemistry: 69(7):1548-54 (ISI-Indexed)
    • Einstein JW, Mustafa MR, Nishigaki I, Rajkapoor B, and Mohd MA (2008). Protective effect of different parts of Cassia fistula on human umbilical vein endothelial cells against glycated protein-induced toxicity in vitro. Methods and findings in experimental and clinical pharmacology 30(8):599-605 (ISI-Indexed)
    • Amudha K, Choy AM, Mustafa MR, and Lang CC (2008). Short-term effect of atorvastatin on endothelial function in healthy offspring of parents with type 2 diabetes mellitus. Cardiovascular therapeutics 26(4):253-61 (ISI-Indexed)
    • M.R.Mukhtar, A.H.A. Hadi, D. Rondeau, P. Richomme, M. Litaudon, M.R. Mustafa, K. Awang (2008). New proaporphines from the bark of Pheobe Scortechini. Natural Products Research, 22 (11): 921-926. (ISI-Indexed)
    • Dharmani M, Mustafa MR, Achike FI, and Sim MK (2008). Involvement of AT(1) angiotensin receptors in the vasomodulatory effect of des-aspartate-angiotensin I in the rat renal vasculature. Peptides 29(10):1773-80 (ISI-Indexed)
    • E. M. Tamil, T.S. Tey, M.R. Mustafa, M.Y.I. Idris and M. Nasir (2008). Automated Clinical Research Mice Movement Detection System. The International Journal of Technology, Knowledge and Society: 4 (6); 63-76. (Non-ISI/Non-SCOPUS)
    • H HUSSEIN, M.R. MUSTAFA, K. F. QUEK, N.S. HASSANUDIN and S. SHAHID (2008). Cross-cultural adaptation and validation of the Malay health assessment questionnaire for use in rheumatoid arthritis. International Journal of Rheumatic Diseases (Formerly APLAR Journal of Rheumatology): 11(3):237 - 240. (SCOPUS-Indexed)
    2007
    • M. Ajay, F.I. Achike, M.A. Mustafa, M.R. Mustafa (2007). Baicalein impairs vascular tone in normal rat aortas: role of superoxide anions. Eur J Pharmacol., 565(1-3):144-50.
    • K. Awang, M.R.Mukhtar, M.R. Mustafa, M. Litaudon, K. Shaari, K. Mohamed and A.H.A. Hadi (2007). New Alkaloids from Pheobe Scortechini. Natural Products Research, 21 (8) : 704-709.
    • Chin LC, Achike FI, Mustafa M.R. (2007). Hydrogen peroxide modulates angiotensin II-induced contraction of mesenteric arteries from streptozotocin diabetic rats. Vascular Pharmacology, 46, 223-228. (ISI-Indexed)
    • M. Ajay, F.I. Achike, M.R. Mustafa (2007). Modulation of vascular reactivity in normal, hypertensive and diabetic rat aortae by a non-antioxidant Flavonoid. Pharmacological Research, 55: 385-391 (ISI-Indexed)
    • Dharmani M, Mustafa M.R, Achike FI, Sim MK (2007). Effects of Angiotensin 1-7 on the actions of angiotensin II in the renal and mesenteric vasculature of hypertensive and Streptozotocin (STZ)-induced diabetic rats. European Journal of Pharmacology, 561: 144-150 (ISI-Indexed)
    • M. Ajay, F.I. Achike, M.A. Mustafa, M.R. Mustafa (2007). Quercetin, a flavonoid antioxidant, modulates endothelium-derived nitric oxide bioavailability in diabetic rat aortas. Nitric Oxide 16, 442-447 (ISI-Indexed)
    • M. Ajay, H.J. Chai, A.M. Mustafa, A.H. Gilani and M.R. Mustafa (2007). Mechanisms of the anti-hypertensive effect of Hibiscus sabdariffa L. calyces. Journal of Ethnopharmacology 109(3): 388-393. (SCOPUS-Indexed)
    2006
    • M. Ajay, F.I. Achike, M.A. Mohd, M.R. Mustafa (2006). Direct effects of quercetin on impaired reactivity of spontaneously hypertensive rat aortas: comparative study with ascorbic acid. Clinical and Experimental Pharmacology and Physiology, 33,345-350. (ISI-Indexed)
    • M. Ajay, F.I Achike, Mustafa Ali Mohd and M.R. Mustafa. (2006) Effects of quercetin on altered vascular reactivity in aortas isolated from streptozotocin-induced diabetic rats. Diabetic Research and Clinical Practice, 73 (1), 1-7 (ISI-Indexed)
    • O. Rozana, H. Ibrahim, A.M. Mohd, M.R. Mustafa and K. Awang (2006). Bioassay-guided isolation of the vasorelaxant active compound from Kaemferia galangal Linn. Phytomedicne, 13, 61-66. (ISI-Indexed)
    • Ajay, M. Mustafa, M. R. (ISI-Indexed)
    2005
    • Mustafa MR, Mahmood AA, Sidik K, Noor SM. Evaluation of wound healing potential of Ageratum conyzoides leaf extract in combination with honey in rats as animal model. International Journal of Molecular Medicine and Advance Sciences. 2005;1(4):406-10. (Non-ISI/Non-SCOPUS)
    • M. Ajay and M.R.Mustafa (2005). , "Chronic treatment with flavonoids prevents endothelial dysfunction in spontaneously hypertensive rat aorta. ", 2005, J. Cardiovasc. Pharmacol., Vol. 46, pg. 36-40,
    • 129M. Dharmani, M.R. Mustafa, F.I. Achike, M.K. Sim, " Effect of des-aspartate-angiotensin I on the actions of angiotensin II in the isolated renal and mesenteric vasculature of hypertensive and STZ- induced diabetic rats.", 2005, Regul. Pept., Vol. 129, pg. 213-219,
    • LY Chung, KF Yap, MR Mustafa, SH Goh, Z Imiyabir, "Muscarinic receptor activity of some Malaysian plant species", Pharmaceutical Biology, Vol. 43, no. 8, 2005, pg. 672-682. (ISI-Indexed)
    2004
    • Mustafa MR, Dharmani M, Kunheen NK, Sim MK. Effects of des-aspartate-angiotensin I on the actions of angiotensin III in the renal and mesenteric vasculature of normo-and hypertensive rats. Regulatory peptides. 2004;120(1-3):15-22. (ISI-Indexed)
    2003
    • Ajay M, Gilani AH, Mustafa MR. Effects of flavonoids on vascular smooth muscle of the isolated rat thoracic aorta. Life sciences. 2003;74(5):603-12. (ISI-Indexed)
    • Lang CC, Jamal SK, Mohamed Z, Mustafa MR, Mustafa AM, Lee TC. Evidence of an interaction between nifedipine and nafcillin in humans. British journal of clinical pharmacology. 2003;55(6):588-90. (ISI-Indexed)
    2002
    • Othman R, Ibrahim H, Mohd MA, Awang K, Gilani AH, Mustafa MR. Vasorelaxant effects of ethyl cinnamate isolated from Kaempferia galanga on smooth muscles of the rat aorta. Planta medica. 2002;68(7):655-7. (ISI-Indexed)
    2001
    • Mustafa MR, Johns EJ. The role of haem oxygenase in renal vascular reactivity in normotensive and hypertensive rats. Journal of hypertension. 2001;19(6):1105-11. (ISI-Indexed)
    2000
    • Mustafa MR, Achike FI. Dicentrine is preferentially antagonistic to rat aortic than splenic alpha 1-adrenoceptor stimulation. Acta pharmacologica Sinica. 2000; 21(12):1165-8. (ISI-Indexed)
    1996
    • Othman I., Fathilah AR., Mohd Saad J, Mohd Yusof M, Mustaffa MR and Nor Azila. Studies on the Venomous Coelenterate: Rhopilema hispidum. J Natural Toxins. 3 (5):361-375 (1996). (ISI-Indexed)
    1995
    • Mustafa MR, Mohamad R, Din L, Wahid S. Smooth muscle relaxant activities of compounds isolated from malaysian medicinal plants on rat aorta and guinea pig ileum. Phytotherapy Research. 1995;9(8):555-8. (ISI-Indexed)
    • Mustafa MR, White E, Hongo K, Othman I, Orchard CH. THE MECHANISM UNDERLYING THE CARDIOTOXIC EFFECT OF THE TOXIN FROM THE JELLYFISH CHIRONEX FLECKERI. Toxicology and Applied Pharmacology. 1995 Aug;133(2):196-206. (ISI-Indexed)
    • Orchard CH, Mustafa MR, White E. OSCILLATIONS AND WAVES OF INTRACELLULAR [CA2+] IN CARDIAC-MUSCLE-CELLS. Chaos Solitons & Fractals. 1995 Mar-Apr;5(3-4):447-58. (ISI-Indexed)
    Book Chapter
    2018
    • Mohadeseh Hasanpourghadi & Mustafa, M.R. (2018). TGF- /Smad Signalling Pathway in Cancer in Recent Trends in Cancer Biology: Spotlight on Signaling Cascades and microRNAs, pp. 151-186.
    2017
    • Farooqi AA. & Ismail, M. (Eds). (2017). Molecular Oncology: Underlying Mechanisms and Translational Advancements. Springer.
    2008
    • M. Ajay and M.R. Mustafa (2008). Vascular Protective Effects of Flavonoids in Animal Models of Hypertension and Diabetes. In Polyphenols and Health: New and Recent advances. Editor: Neville Vasallo. Nova Science Publishers, USA. (Non-ISI/Non-SCOPUS)
    RESEARCH PROJECT
    (Project title),(Role),(Duration),(Level)
    NKEA Pertanian Research Scheme
  • Protective effects of standardised Labisia pumila extracts against vascular dysfunction in diabetes , Principal Investigator(PI), 2015 - 2017 (National)
  • High Impact Research (HIR)
  • Mechanisms of the cardiovascular therapeutic potentials of boldine and nitrite in animal models of diabetes mellitus and hypertension H- 20001-00-E000055 , Principal Investigator(PI), 2012 - 2014
  • Circulating microRNAs as Novel Biomarkers for Early Detection of Atherosclerosis , Consultant, 2011 - 2014
  • Molecular Mechanisms of Drugs Action , Principal Investigator(PI), 2011 - 2015
  • Geran Penyelidikan Universiti Malaya (UMRG)
  • Endothelial protective activity of aporphine alkaloids in animals models of diabetes mellitus and hypertension , Consultant, 2011 - 2012 (National)
  • Molecular Staging of Senescence in Endothelial Cells , Consultant, 2011 - 2012 (National)
  • Tittle: TARGETING NUCLEAR FACTOR (NF) KAPPA B PATHWAY BY PHYTOCHEMICALS DERIVED FROM MALAYSIAN PLANTS FOR TREATMENT OF CANCER , Principal Investigator(PI), 2009 - 2012 (National)
  • Effects of chronic treatment of angiotensin peptides in development of type II Diabetes mellitus in GK rats, Principal Investigator(PI), 2007 - 2009 (National)
  • ScienceFund
  • Molecular Characteristics of the Anti-inflammatory activity of Malaysian Seaweeds, Consultant, 2006 - 2008 (National)
  • Role of free radicals in the development of endothelial dysfunction in diabetes mellitus, Principal Investigator(PI), 2006 - 2009 (National)
  • SAGA Fund, Academy of Science Malaysia
  • Syntheses of Analogs of Ethyl Cinnamate Vasorelaxant Compounds Based on In Silico and NMR Orientation in the Active Site of Cytochrome P- 450. , Consultant, 2005 - 2007
  • Yayasan Felda Berhad
  • Enhancement of the Natural Production of Carpaine in Papaya (Carica papaya L.) var. Eksotika through Biotechnological Approach , Principal Investigator(PI), 2004 - 2006 (National)
  • SUPERVISION
    External Supervision
    (Title of Thesis),(Name of Candidates),(Institution),(Academic Level)
    Completed
    • Measurement of vascular reactivity of rats fed with repeatedly heated oils, Leong Xin Fang, M0100121 (Post Graduate Student)
    Postgraduate Student
    (Title of Thesis),(Name of Candidates),(Institution),(Academic Level)
    Completed
    • Cardiovascular effects of Hibiscus Sabdariffa, Chai Hann Juang, University of Malaya (UM) (Post Graduate Student)
    • 5-HT receptor binding activities of Lisea sessilis plant, Lo Mee Wah (Post Graduate Student)
    • Pharmacokinetic and pharmacodynamic studies of novel BH4 analogues, Mohd Yusmaidie Aziz, University of Malaya (UM) (Post Graduate Student)
    • Antiinflammatory activities of natural products, Mouna Achoui, University of Malaya (UM) (Post Graduate Student)
    • Endothelial protective efefcts of aporphine alkaloids, Lau Yea Siang, University of Malaya (UM) (Post Graduate Student)
    • Vascular protective effects of flavonoids in diabetic animals, Umelo Aloysius Iguegbe, University of Malaya (UM) (Post Graduate Student)
    • Bioassay guided isolation of vasoactive constituents from Hibiscus Sabdariffa, Nauman Aziz (Post Graduate Student)
    • Comparative Biochemical, Pharmacology and Ultrastructural Studies on Malaysian Jellyfishes, Rabindra Shair Baharuddin, University of Malaya (UM) (Post Graduate Student)
    • Effects of Des-Asp Angiotensin I on renal vasculature, Dharmani Devi (Post Graduate Student)
    • Direct and modulatory effects of angiotensin peptides on vascular contractility in hypertensive rats, Nabisah K Kunheen (Post Graduate Student)
    • AntiLipoxygenase and 5HT1A-receptor binding activities of Malaysian Plants, Soo Wei kwan (Post Graduate Student)
    • Isolation and characterisation of compounds with muscarinic receptor activity from Melicope subunifoliolata and Ficus septica, Yap Kim Fah, University of Malaya (UM) (Post Graduate Student)
    • Role of K+ Channels in vascular effects of insulin, Gopal Subramaniam (Post Graduate Student)
    • Pharmacology of flavonoids, Macha Ajay (Post Graduate Student)
    • Asssessment of plant extracts for insulin-like properties using rat adipocyte primary culture, Lim Siang ling (Post Graduate Student)
    • Role of Reactive Oxygen Species in diabetic vasculopathy in microvessels, Chin Leh Choong, University of Malaya (UM) (Post Graduate Student)
    • Vascular dysfunction and atheroslerotic burden in common cardiovascular diseases, Amudha Kadirvelu (Post Graduate Student)
    Ongoing
    • Pharmacological evaluation of the antidiabetic effects of Cassia fistula, John Wilkins Einstein (Post Graduate Student)
    • Cellulat toxicity evaluations of herbal medicines, Noorasyikin Shamsuddin (Post Graduate Student)
    • Molecular and Biochemical analysis of Interluekin 18 in Malaysian Asthmatics, Devika a/p Chinayah (Post Graduate Student)
    • Pharmacogenomics of Malaysian Asthmatic patients, Vijaya Lechimi Raj, University of Malaya (UM) (Post Graduate Student)
    SOCIAL RESPONSIBILITY ACTIVITIES
    (Contribution to Society),(Duration),(Level)
    • Scientific Committee for UM Research Carnival 2015, 08/10/2015 to 10/10/2015
    • International Silk Road Academy of Medical Sciences meeting Xinjiang Medical University, CHINA, 15/10/2014 to 17/10/2014
    ACADEMIC/PROFESSIONAL SERVICES
    Evaluation Activity
    (Activity),(Duration),(Category)
  • External Examiner for BDS Yr 2 program at MAHSA University, 2015 (Dental Program)
  • PONE-D-14-20760 Enhanced protective effect of the combination of Uncaria and Semen Raphani on vascular endothelium in spontaneously hypertensive rats , 2014 (Article in Journal)
  • Review of of PLOS ONE article: PONE-D-11-06669 A Blueberry Enriched Diet Attenuates Nephropathy in a Rat Model of Hypertension via Reduction in Oxidative Stress, 2011 to 2011 (Article in Journal)
  • Ref.: Ms. No. JEP-D-11-02174 Vasorelaxant effect of an infusion of Baccharis trimera (Less.) DC. on precontracted rat aortic rings. Journal of Ethnopharmacology , 2011 to 2011 (Article in Journal)
  • Experimental Biology and Medicine Manuscript No. 1110-RM-357-, 2011 to 2011 (Article in Journal)
  • Expert Linkages
    (Linkages Description),(Organisation),(Duration of Involvement),(Level)
  • AHLI PANEL TASK FORCE BAGI INSTRUMEN PUSAT KECEMERLANGAN PENGAJIAN TINGGI (HICoE), Kementerian Pelajaran Malaysia, 2015 (National)
  • Consultative Meeting for Organisation of Islamic Countries, Committee of Scientific and Technical Cooperation (COMSTECH), 2014 (International)
  • Academic/Technical Contribution
    (Activity),(Organisation),(Duration),(Role)
  • Technical Committee for Research and Development in Herbal Medicine, NATIONAL COMMITTEE FOR RESEARCH AND DEVELOPMENT IN HERBAL MEDICINE (NRDHM) , 2014 - Present (Committee Member)
  • Panel evaluator (Technical) for monitoring and evaluation of proposals for grants for RESEARCH ACCULTURATION COLLABORATIVE EFFORTS (RACE), Ministry of Education/, 2013 - 2014 (Technical Advisor)
  • AWARD AND STEWARDSHIP
    (Name of Award/Stewardship),(Awarding Institution),(Year Awarded),(Type of Award)
    • KHIDMAT SETIA 30 AWARD, , 2013
    • CERTIFICATE OF EXCELLENT SERVICE, University of Malaya, 2009
    • EXCELLENCE SERVICE AWARD, University of Malaya, 2008
    • CERTIFICATE OF EXCELLENT SERVICE, University of Malaya, 2007
    • CERTIFICATE OF EXCELLENT SERVICE, University of Malaya, 2006
    • EXCELLENCE SERVICE AWARD, University of Malaya, 2005
    • Royal Society UK-Malaysian Fellowship for a postdoctorate research attachment at the University of Birmingham, U.K., Royal Society UK, 1998
    • JSPS Postdoctoral Research Attachment, Japanese Society for the Promotion of Science (JSPS), 1992
    • IBRO-Pan Asian First Intensive Workshop on Basic Neuroscience fellowship, International Brain Research Organisation, 1988
    CONSULTANCY PROJECT
    (Project title),(Organisation),(Duration),(Role),(Level)
    • Chronic effects of Brands's Essence of Chicken Extracts on vascular endothelial function in hypertensive animals., Cerebos Pacific Limited, 01/04/2005 to 01/04/2007 (International)
    • Hypoglycemic effects of bitter gout in normal and diabetic rats, Jun Herng Sdn. Bhd., 01/04/2004 to 01/04/2006 (International)
    • Oral Toxicity test of Olescair in rats, Autoimmune Sdn. Bhd., 01/04/2005 to 01/04/2007 (International)
    PAPER PRESENTED
    (Title),(Event),(Date Presented),(Organiser),(Level)
    PLEANARY SPEAKER
  • ELEPHANT TRUNK, BIRDS NEST, CAT WHISKERS AND FATIMA S DAGGER: CAN NATURAL PRODUCTS FROM MALAYSIA TREAT DIABETES MELLITUS?, 5TH INTERNATIONAL MEDITERRANEAN SYMPOSIUM ON MEDICINAL AND AROMATIC PLANTS/5TH INTERNATIONAL SYMPOSIUM ON PHARMACEUTICAL AND BIOMEDICAL SCIENCES APRIL, 24-28, 2019 / CAPPADOCIA - TURKEY, 24/04/2019 to 28/04/2019, Association of Medicinal and Aromatic Plants of Mediterranean (International)
  • MINING OF PHYTOCHEMICALS FOR CARDIOVASCULAR PROTECTION, 5TH INTERNATIONAL CONFERENCE, TECHNOLOGY DEVELOPMENT ON AGRICULTURE, ENERGY & ENVIRONMENTAL ENGINEERING FOR GREEN WORLD , 18/02/2016 to 19/02/2016, Vivekenandha Educational Institution, INDIA (International)
  • Modulation of Oxidative stress and Endothelial protection by plant-derived products, International Conference on Natural Products 2014, 18/03/2014 to 19/03/2014, Malaysian Natural Products Society (International)
  • INVITED SPEAKER
  • CHRONIC TREATMENT WITH PAEONOL PROTECTS AGAINST TUNICAMYCIN-INDUCED ENDOTHELIAL DYSFUNCTION THROUGH ATTENUATING OXIDATIVE STRESS AND ENDOPLASMIC RETICULUM STRESS, SCIENTIFIC FRONTIERS IN NATURAL PRODUCT BASED DRUGS 2017, 06/07/2017 to 07/07/2017, National University of Singapore (International)
  • ENDOTHELIAL PROTECTIONS AND CVS HEALTH: MODULATIONS OF OXIDATIVE STRESS BY PLANT DERIVED PRODUCTS, SYMPOSIUM OF TRADITIONAL MEDICINES IN COUNTRIES ALONG MARITIME SILK ROAD , 05/08/2016 to 06/08/2016, Zhejiang University (International)
  • PAENOL PROTECTS AGAINST TUNICAMYCIN-INDUCED OXIDATIVE STRESS AND ENDOTHELIAL DYSFUNCTION VIA AMPK/PPAR PATHWAYS, 13TH ASIA PACIFIC FEDERATION OF PHARMACOLOGIST MEETING, 01/02/2016 to 03/02/2016, ASIA PACIFIC FEDERATION OF PHARMACOLOGISTS (International)
  • Endothelial protective effects and mechanisms of the NO releasing effects of the anti-hypertensive herb, Apocynum venetum, IUPHAR World Conference on the Pharmacology of Natural and Traditional Medicine,, 22/07/2015 to 24/07/2015, IUPHAR (International)
  • Endothelial dysfunctions and CVS Health: Role of Natural Products, Joint Malaysia-UK symposium on natural Product Chemistry and Drug Discovery, 13/12/2014 to 14/12/2014, International Medical University and Royal Society of Chemistry, UK (International)
  • ENDOTHELIAL PROTECTION AND MODULATION OF OXIDATIVE STRESS BY PLANTDERIVED PRODUCTS, 2nd International Conference on Natural Health, 26/10/2014 to 28/10/2014, University of Mostagenam (International)
  • Boldine treatment improves endothelial dysfunction in streptozotocin-induced diabetes, 6th International Symposium on Vascular Biology 2012, 24/03/2012 to 25/03/2012, China Medical University, Taiwan (International)
  • Pharmacological characterization of the mechanisms of the antioxidant effects of boldine in hypertensive rats, 4th International Symposium on Vascular Biology 2010, 27/03/2010 to 28/03/2010, China medical University, Taichung, Taiwan (International)
  • ORAL PRESENTER
  • VERNODALIN INDUCE APOPTOSIS IN BREAST CANCER CELLS THROUGH ACTIVATION OF FORKHEAD BOX TRANSCRIPTION FACTOR, FOXO3A, 2ND MEDITERRANEAN SYMPOSIUM ON MEDICINAL AND AROMATIC PLANTS, 22/04/2015 to 25/04/2015, NATURAL PRODUCTS SOCIETY OF TURKEY (AMAPMED) (International)
  • Free radical scavenging and NO releasing effects of the antihypertensive herb, Apocynum venetum, 3rd International congress of Traditional Chinese Modern Medicine and Traditional Uyghur Medicine, 15-20 Oct 2014, 15/10/2014 to 20/10/2014, Xinjiang University (International)
  • Developing a TNF sensitization assay for screening of potential NF-kB inhibitors using the xCELLigence technology. , xCELLigence Symposium and User Meeting 2010 27-29 Oct 2010, , 27/10/2010 to 29/10/2010, Roche Applied Scinces (International)