Curriculum Vitae
BIOGRAPHY
BIOGRAPHY :
Dr. Chong Pan Pan is highly qualified with B.Sc. (Hons) in Microbiology (2001), M.Sc. in Biochemistry (2004) and completed her Ph.D. in Tissue Engineering (2013). After that, she worked as a post-doctoral research fellow (2013-2016) and was later inducted as a senior lecturer (2016-present) at the National Orthopaedic Centre of Excellence in Research and Learning (NOCERAL), Department of Orthopaedic Surgery, Faculty of Medicine, University of Malaya (UM), Malaysia. Additionally, she is in charge of setting up the Good Manufacturing Practice (GMP) Laboratory in NOCERAL. She has also been put in charge of the newly provided clinical service using platelet-derived extracellular vesicles (P-EVs) to treat lateral epicondylitis, plantar fasciitis, osteochondral defect, delayed union, knee osteoarthritis, etc. The P-EVs service is provided in the University Malaya Medical Centre (UMMC) and the University Malaya Specialist Centre (UMSC). Her research interest involves the current and innovative area of tissue engineering and manipulating adult mesenchymal stem cells (MSCs) for future use as biological therapies for poorly regenerating tissues. Her work focuses on driving the adult MSCs from bone marrow, peripheral blood, and adipose tissue along chondrogenic lineages for later transplantation to replace worn-out joint cartilage in patients suffering from joint disorders, including trauma or osteoarthritis. To attest to her work, Dr. Chong has published in several high-quality (Q1/high impact factor) peer-reviewed journals and presented her works extensively and globally at numerous international conferences. At that time, she also won several awards, including top prizes at the regional level, such as the Young Investigator Awards, Young Investigator Best Paper Award, L’Oréal Malaysia for Women in Science, Best Poster/Oral Presentations and travel fellowships, etc. In addition, she has participated in several biotechnology exhibitions and business idea competitions. Furthermore, she won many innovation awards for her work on MSCs and P-EVs as biological therapies for tissue regenerations. She has also developed intellectual property related to the novel work, which has been successfully patented.
AREAS OF EXPERTISE
-
BLOOD PRODUCTPlatelet-derived extracellular vesicles
-
ORTHOPAEDIC RESEARCHArticular cartilage regeneration
-
ANIMAL MODELS OF OSTEOARTHRITIS AND CARTILAGE DEFECTS (RABBIT AND RAT)
-
MOLECULAR AND STRUCTURAL BIOLOGY
-
GENOMICwhole genome shotgun sequencing, bioinformatics
-
STEM CELL TECHNOLOGYMesenchymal stem cells
-
TISSUE ENGINEERING
-
RADIOLOGICAL TECHNOLOGYHigh-resolution peripheral quantitative computed tomography
ACADEMIC QUALIFICATION
- PhD (Tissue Engineering), (Kejuruteraan Tisu)Universiti Malaya (UM)
- MSc (Biochemistry), (Biochemistry)Universiti Kebangsaan Malaysia (UKM)
- BSc (Hons)(Microbiology), (Mikrobiologi)Universiti Kebangsaan Malaysia (UKM)
ADMINISTRATIVE DUTIES
- Program Sarjana Sains Perubatan (Perubatan Regeratif) / Master of Medical Science Program (Regenerative Medicine)13 Jan 2023 - 12 Jan 2025 (Department)
- Laboratory Officer in Charge22 Oct 2020 - 31 Dec 2021 (University Malaya)
- Manager04 Jan 2016 - 31 Dec 2021 (Department of Orthopaedic Surgery, Faculty of Medicine)
- Coordinator03 Jul 2017 - 31 Dec 2021 (Department of Orthopaedic Surgery, Faculty of Medicine)
- Laboratory Officer in Charge22 Oct 2020 - 31 Dec 2021 (Department of Orthopaedic Surgery, Faculty of Medicine)
- Coordinator20 Sep 2019 - 20 Sep 2021 (Department of Orthopaedic Surgery, Faculty of Medicine)
- Coordinator20 Sep 2019 - 31 Dec 2020 (Department of Orthopaedic Surgery, Faculty of Medicine)
- Coordinator23 Dec 2013 - 23 Dec 2020 (Department of Orthopaedic Surgery, Faculty of Medicine)
- Senior Lecturer25 Aug 2015 - 25 Aug 2020 (Department of Orthopaedic Surgery, Faculty of Medicine)
- Committee members: Jawatankuasa Penilainan Teknikal dan Harga27 Sep 2019 - 31 Dec 2019 (Department of Orthopaedic Surgery, Faculty of Medicine)
- Coordinator23 Sep 2013 - 01 Jun 2017 (University Malaya)
MEMBERSHIPS
- INVITED MEMBERSHIP, MEMBERSince 2022 (International)
- MEMBER OF NATIONAL ORTHOPAEDIC CENTRE OF EXCELLENCE IN RESEARCH AND LEARNING (NOCERAL), MEMBER2023 to 2023 (University)
- INTERNATIONAL ORTHOPAEDIC POSTGRADUATE SYMPOSIUM, CHAIRMAN2019 to 2023 (International)
- ASIA PACIFIC ORTHOPAEDIC ASSOCIATION (APOA) 2020, COMMITTEE2019 to 2022 (International)
- ASIAN CARTILAGE REPAIR SOCIETY (ACRS), OTHERS2017 to 2022 (International)
- MALAYSIAN ORTHOPAEDIC ASSOCIATION (MOA), OTHERS2019 to 2020 (National)
AWARD AND STEWARDSHIP
- CERTIFICATE OF EXCELLENT SERVICEUniversity of Malaya, 2023 (University)
- My UM Pitch Competition: First Place (Universiti Malaya Research Carnival 2022), 8-10th January 2023, Research Management & Innovation Complex Universiti MalayaUNIVERSITI MALAYA, 2023 (University)
- 2nd winner of Indonesian Orthopaedic Investigator Award - ASEAN Orthopaedic Research Society Awards (AORS) - Basic science categoryIndonesian Orthopaedic Association, 2019 (International)
- Business Idea Competition: 2nd prize (Title: Plate-derived Extracellular Vesicles)Innovation Forum Kuala Lumpur, 2018 (National)
- Orthopaedic Surgery Research Project Award: Research Proposal CompetitionNational Orthopaedic Centre of Excellence in Research and Learning (NOCERAL), Department of Orthopaedic Surgery, Faculty of Medicine, University of Malaya; Malaysia Orthopaeic Association (MOA); StemTech International., 2017 (National)
- Finalist for the best podium presentationInternational Cartilage Repair Society (ICRS) Heritage Summit 2017, Gothenburg, Sweden., 2017 (International)
- Platinum Award - Young Investigator Best Paper AwardThe 4th Asian Cartilage Repair Society Congress 2016, October 14 to October 17, 2016 at Vision Plaza, Beijing, China., 2016 (International)
- Travel Award - The 4th Japan Medical Innovation Tour (JMIT) 2016Kyushu University, Japan, 2016 (International)
- Young Investigator Travel Award. Date: 13-17 October 2014.The 20th International Bone Densitometry Workshop (IBDW 2014), Hong Kong, 2014 (International)
- Three-minute Thesis Competition, University of Malaya, July 2013, Second place (faculty level)University of Malaya, 2013 (University)
- Post-graduate Research Award: First Prize (Category: Biotechnology; Level: PhD; Oral presentation) at the 19th Scientific Meeting of the Malaysian Society for Molecular Biology and Biotechnology (MSMBB), 30th October to 1st November 2012University Malaya, 2012 (National)
- Travel Fellowship: 2nd University of Hong Kong (HKU) - Pasteur Cell Biology Course (18th March - 1st April 2010) for Research Postgraduate Students (MPhil and PhD)University of Hong Kong, 2010 (International)
- Loreal Malaysia for Women in Science Fellowships 2010Loreal-UNESCO, 2010 (National)
- Silver Medal, 13th - 15th January 2009. Research Project: Human Amniotic Membrane For the Application of Clinical Tissue EngineeringUniversity of Malaya: Research, Invention & Innovation Expo 2009, 2009 (National)
- Gold Medal, 13th-15th January 2009, Research Project: Human blood-derived mesenchymal stem cells: A new potential cell therapy to repair cartilage defects.University of Malaya: Research, Invention & Innovation Expo 2009, 2009 (National)
- Special Award - Best in Cluster (Biosciences & Biotechnology). 13th - 15th January 2009. Research Project: Human blood-derived mesenchymal stem cells: A new potential cell therapy to repair cartilage defects.University of Malaya: Research, Invention & Innovation Expo 2009, 2009 (National)
- Session Winner ISCOMS (2009): poster (cell biology), 2nd - 5th June 2009The International Student Congress of Medical Sciences (ISCOMS), University Medical Center Groningen (UMCG), the Netherlands, 2009 (International)
- The International Student Congress of Medical Sciences (ISCOMS) Research Fellowship, 8th - 19th June 19 2009University Medical Center Groningen (UMCG), the Netherlands, 2009 (International)
- Travel Awards: July 8th - 11st July 2009.7th International Society for Stem Cell Research Congress Barcelona, Spain, 2009 (International)
- Best Poster Presentation Award. Tissue Engineering and Regenerative Medicine (TERMIS) 2nd World Congress. In Conjunction with 2009 Seoul Stem Cell Symposium. Lotte Hotel World, Seoul, Republic of Korea. August 31 until September 3, 2009. Title: Microarray-Based Discovery Of Potential Genes Involved In Chondrogenesis Of Mesenchymal Stem Cells Derived From Human Bone MarrowTissue Engineering and Regenerative Medicine (TERMIS) 2nd World Congress, 2009 (International)
- Bronze Medal: Human Blood-Derived Mesenchymal Stem Cells: A New Potential Cell Therapy To Repair Cartilage Defects. At Kuala Lumpur Convention Centre, 8-10 October 2009.The International Exposition of Research and Invention of Institutions of Higher Learning, 2009 (International)
- 8th Dr Ranjeet Bhagwan Singh National Fellowship Human Embryonic Stem Cell: Culture and Maintenance. 14th 15th December 2009Ministry 0f Science, Technology and Innovation, Academy of Sciences Malaysia and the International Medical University, 2009 (National)
- Asean Best Poster Presentations: First Prize. AOA-MOA Combined Scientific Meeting 2008: Combined Meeting of (1) 28th Asean Orthopaedic Association Congress (2) 38th Malaysian Orthopaedic Association AGM/ASM (incorporating the 4th Instructional Course of the American Academy of Orthopaedic Surgeons). 26th 29th June 2008. Title: Human blood-derived progenitor cells: a new potential cell therapy to repair cartilage defectsAOA-MOA Combined Scientific Meeting 2008, 2008 (International)
- Theme 3 - Cell and Molecular Biology: Third Prize (Poster Presentation). 15th - 17th December 2008. Title: Identification of human bone marrow derived mesenchymal stem cells (MSCS) for studies of chondrogenic differentiation13th Biological Sciences Graduate Congress, Singapore, 2008 (International)
- Silver medal: Research & Innovation Expo 2005, University Kebangssaan Malaysia, 14th ?16th July 2005. CBASS: Database of sea bass sequences (http://genome.ukm.my/cbass/)University Kebangssaan Malaysia, 2005 (University)
- Certificate of Appreciation: Involving a 40 Members Team Which Undertook The Sequencing, Assembly and Analysis of Two Coronavirus Genomes (Local Isolated from Avian & Porcine) Within a One Week Time Frame, Ministry of Science, Technology & The Environment (Moste), Malaysia, 2003, (National)Ministry of Science, Technology & The Environment (Moste), Malaysia, 2003 (Government)
PUBLICATIONS
Article in Journal
-
Hassan, Nur Hidayah; Ahmad, Raja Elina; Kamarul, Tunku; Chong, Pan Pan (2023). Allogenic platelet-rich plasma for treating cartilage injury: A systematic review of the evidence on the basic sciences for potential future applications, CELLS TISSUES ORGANS. . doi:10.1159/000535018
-
Lim, Wei Qing; Luk, Kie Hoon Michelle; Lee, Kah Yee; Nurul, Nasuha; Loh, Sin Jade; Yeow, Zhen Xiong; Wong, Qi Xuan; Looi, Qi Hao Daniel; Chong, Pan Pan; How, Chee Wun; Hamzah, Sharina; Foo, Jhi Biau (2023). Small Extracellular Vesicles' miRNAs: Biomarkers and Therapeutics for Neurodegenerative Diseases, PHARMACEUTICS. 15(4). doi:10.3390/pharmaceutics15041216
-
Aizah, Nik; Chong, Pan Pan; Kamarul, Tunku (2021). Early Alterations of Subchondral Bone in the Rat Anterior Cruciate Ligament Transection Model of Osteoarthritis, CARTILAGE. 13(2_SUPPL), 1322S-1333S. doi:10.1177/1947603519878479
-
Foo, J. B., Looi, Q. H., Chong, P. P., Hassan, N. H., Yeo, G. E. C., Ng, C. Y., . . . Law, J. X. (2021). Comparing the Therapeutic Potential of Stem Cells and their Secretory Products in Regenerative Medicine. Stem Cells International, 2021, 30. doi: 10.1155/2021/2616807
-
Chong, P. P., Panjavarnam, P., Ahmad, W., Chan, C. K., Abbas, A. A., Merican, A. M., . . . Kamarul, T. (2020). ( )Mechanical compression controls the biosynthesis of human osteoarthritic chondrocytes in vitro. Clinical Biomechanics, 79, 8. doi: 10.1016/j.clinbiomech.2020.105178
-
Othman, R., Chong, P. P., Kadri, N. A., Kamarul, T. (2019). A Systematic Review on Peripheral Blood-derived Mesenchymal Stem Cells as a Therapy for Cartilage Repair. Sains Malaysiana, 48(9), 1947-1958. doi:10.17576/jsm-2019-4809-16
-
Othman, Rufaidah; Chong, Pan Pan; Kadri, Nahrizul Adib; Kamarul, Tunku (2019). A Systematic Review on Peripheral Blood-derived Mesenchymal Stem Cells as a Therapy for Cartilage Repair, SAINS MALAYSIANA. 48(9), 1947-1958. doi:10.17576/jsm-2019-4809-16
-
Chong, P. P., Selvaratnam, L., Abbas, A. A., Kamarul, T. (2018). Factors Influencing the Successful Isolation and Expansion of Aging Human Mesenchymal Stem Cells. Open Life Sciences, 13(1), 279-284. doi:10.1515/biol-2018-0034
-
Moradi, A., Ataollahi, F., Sayar, K., Pramanik, S., Chong, P. P., Khalil, A. A., Kamarul, T., Pingguan-Murphy, B. (2016). Chondrogenic potential of physically treated bovine cartilage matrix derived porous scaffolds on human dermal fibroblast cells, Journal of Biomedical Materials Research Part A. 104(1245-256), Article
-
Mirza, E. H., Pan-Pan, C., Ibrahim, W., Djordjevic, I., Pingguan-Murphy, B. (2015). Chondroprotective effect of zinc oxide nanoparticles in conjunction with hypoxia on bovine cartilage-matrix synthesis, Journal of Biomedical Materials Research Part A. 103(113554-3563), Article
-
Chong, P. P., Selvaratnam, L., Abbas, A. A., Kamarul, T. (2012). Human peripheral blood derived mesenchymal stem cells demonstrate similar characteristics and chondrogenic differentiation potential to bone marrow derived mesenchymal stem cells, Journal of Orthopaedic Research. 30(4), 634-642
-
Tay, L. X., Ahmad, R. E., Dashtdar, H., Tay, K. W., Masjuddin, T., Ab-Rahim, S., Chong, P. P., Selvaratnam, L., Kamarul, T. (2012). Treatment Outcomes of Alginate-Embedded Allogenic Mesenchymal Stem Cells Versus Autologous Chondrocytes for the Repair of Focal Articular Cartilage Defects in a Rabbit Model, American Journal of Sports Medicine. 40(1), 83-90
-
Chong, Pan-Pan; Adnan, Adura Mohd.; Wan, Kiew-Lian (2011). Characterisation of Simple Sequence Repeats in the Asian Seabass, Lates calcarifer by Random Sequencing, SAINS MALAYSIANA. 40(5), 497-502
-
Dashtdar, H., Rothan, H. A., Tay, T., Ahmad, R. E., Ali, R., Tay, L. X., Chong, P. P., & Kamarul, T. (2011). A Preliminary Study Comparing the Use of Allogenic Chondrogenic Pre-Differentiated and Undifferentiated Mesenchymal Stem Cells for the Repair of Full Thickness Articular Cartilage Defects in Rabbits, Journal of Orthopaedic Research. 29(9), 1336-1342. doi:10.1002/jor.21413
-
Othman R., Chong P.P., Kadri N.A., Kamarul T. (2019). A systematic review on peripheral blood-derived mesenchymal stem cells as a therapy for cartilage repair, Sains Malaysiana. 48(9), 1947-1958. doi:10.17576/jsm-2019-4809-16
-
Chong, P. P., Panjavarnam, P., Ahmad, W., Chan, C. K., Abbas, A. A., Merican, A. M., Pingguan-Murphy, B., & Kamarul, T. (2020). Mechanical compression controls the biosynthesis of human osteoarthritic chondrocytes in vitro. Clinical biomechanics (Bristol, Avon), 79, 105178. https://doi.org/10.1016/j.clinbiomech.2020.105178
-
Aizah, N., Chong, P. P., & Kamarul, T. (2019). Early Alterations of Subchondral Bone in the Rat Anterior Cruciate Ligament Transection Model of Osteoarthritis. CARTILAGE. https://doi.org/10.1177/1947603519878479
-
Rufaidah Othman, Pan Pan Chong, Nahrizul Adib Kadri, Tunku Kamarul (2019). A Systematic Review on Peripheral Blood Mesenchymal Stem Cells: A Cell Therapy for Cartilage Repair. Sains Malaysiana 48(9)(2019): 1947 1958
-
PP Chong, L Selvaratnam, AA Abbas, T Kamarul. (2018). Factors Influencing the Successful Isolation and Expansion of Aging Human Mesenchymal Stem Cells. Open Life Sciences 13 (1), 279-284
-
Moradi A, Ataollahi F, Sayar K, Pramanik S, Chong PP, Khalil AA, Kamarul T, Pingguan-Murphy B. 2016. Chondrogenic potential of physically treated bovine cartilage matrix derived porous scaffolds on human dermal fibroblast cells. J Biomed Mater Res Part A 2016:104A:245 256
-
Mirza EH, Pan-Pan C, Wan Ibrahim WM, Djordjevic I, Pingguan-Murphy B. 2015. Chondroprotective effect of zinc oxide nanoparticles in conjunction with hypoxia on bovine cartilage-matrix synthesis. J Biomed Mater Res A. 2015 May 1. doi: 10.1002/jbm.a.35495.
-
Tay LX, Ahmad RE, Dashtdar H, Tay KW, Masjuddin T, Ab-Rahim S, Chong PP, Selvaratnam L, Kamarul T. (2012). Treatment outcomes of alginate-embedded allogenic mesenchymal stem cells versus autologous chondrocytes for the repair of focal articular cartilage defects in a rabbit model. Am J Sports Med. 40(1):83-90.
-
Chong, P.P., Selvaratnam, L. and Kamarul, T. (2011). Characterization of undifferentiated human bone marrow and blood derived mesenchymal stem cells and their potential for chondrogenic differentiation. BMC Proc. 2011; 5(Suppl 1): P85. PMCID: PMC3019515.
-
Dashtdar H, Rothan HA, Tay T, Ahmad RE, Ali R, Tay LX, Chong PP, Kamarul T. (2011). A preliminary study comparing the use of allogenic chondrogenic pre- differentiated and undifferentiated mesenchymal stem cells for the repair of full thickness articular cartilage defects in rabbits. J Orthop Res. 29(9): 1336-1342
-
Pan-Pan Chong, Adura Mohd-Adnan and Kiew-Lian Wan (2011). Characterisation of simple sequence repeats in the asian seabass, Lates calcarifer by random sequencing. Sains Malaysiana 40(5): 497 502
-
Pan-Pan Chong, T. Kamarul, Khairussulhi Jalil, Noor Azera Bakar and Ng LL. (2008). Processing and bioburden analysis of human amniotic membrane for biological and tissue engineering application - a preliminary report. The Journal of the ASEAN Orthopaedic Association Vol 19 No.1 June: 28-34
-
Pan-Pan Chong, Adura Mohd-Adnan and Kiew-Lian Wan. (2005). Pembinaan dan Pencirian Perpustakaan Genom Siakap (Lates calcarifer). Sains Malaysiana 34(1): 27- 32
Chapter in Books
Article in Proceeding
-
Masjudin, T.; Chong, Pan-Pan; Kamarul, T.; Selvaratnam, L.; Ab-Rahim, S.; Sara, T. (2007). Repair of rabbit focal articular cartilage defects with autologous chondrocytes embedded in alginate, 3RD KUALA LUMPUR INTERNATIONAL CONFERENCE ON BIOMEDICAL ENGINEERING 2006. 15, 700-+
Other Publications
- Mo Zhiyue. 2023. Cell therapy attacks degenerative diseases! Experts from South Korea and Malaysia reveal the latest regeneration technology. Global Bio and Investment Magazine, Link: https://news.gbimonthly.com/tw/article/show.php?num=57370&range=news&fbclid=IwAR2KXpgur2BQTXAMLMBpn0wT7yB8t8m2m8tZXnROdgECETY61lTya8qgjC4 - Mass Media(Newspaper,Radio,Tv,Popular Magazine)
- Jonas Fernande. Getting stuck in, literally: there are multiple modalities at one's disposal to treat knee conditions. 2022. July-August 2022. Vol5:40 PP19292/03/2018 (034850) - Mass Media(Newspaper,Radio,Tv,Popular Magazine)
RESEARCH PROJECT
National
- 2022 - 2025, Fundamental Research Grant Scheme (FRGS)Investigating The Role Of Peripheral Blood Mirnas As Potential Diagnostic, Prognostic, And Therapeutic Targets In Treating Osteoarthritis ( Co-Researcher)
- 2021 - 2024, Prototype Research Grant Scheme (PRGS)Clinical Development Of Autologous Platelet-derived Extracellular Vesicles (pev) Combined With Peripheral Blood-derived Mesenchymal Stem Cells (pb-msc) As A Prototype For The Treatment Of Osteoarthritis: Clinical Trials Involving Phase I And Phase Ii ( Principal Investigator(PI))
- 2021 - 2024, Fundamental Research Grant Scheme (FRGS)Investigating The Effects Of Moderate Physical Exercise On Cartilage Degeneration And Early Subchondral Bone Remodelling At The Tibial Plateau Of Anterior Cruciate Ligament Transected Osteoarthritis Rat Models ( Co-Researcher)
- 2023 - 2024, RU GeranIdentification Of Crucial Mirnas Expressed In Patients With End-stage Knee Osteoarthritis ( Principal Investigator(PI))
- 2019 - 2022, Fundamental Research Grant Scheme (FRGS)Functional Properties To Distinguish Perivascular Stem Cells From Other Mesenchymal Stromal Cells In Cartilage Tissue Engineering ( Principal Investigator(PI))
- 2016 - 2020, Skim Geran Penyelidikan Trans-Displin (TRGS)Establishing Microcellular Biomechanical Alterations In Cartilage Tissue That May Be Associated With The Cartilage Disease In Vivo ( Co-Researcher)
- 2017 - 2019, Bantuan Kecil Penyelidikan (BKP)The nutraceutical potential of curcumin in reducing the progression of osteoarthritis: alterations in subchondral bone and articular cartilage properties in the rat anterior cruciate ligament transection model of post-traumatic osteoarthritis ( Principal Investigator(PI))
- 2018 - 2021, Private FundingTreatment of articular cartilage defects in the rabbit knees with non-mobilized peripheral blood-derived mesenchymal stem cells ( Principal Investigator(PI))
- 2016 - 2019, Trans Disciplinary Research Grant Scheme (TRGS)Predicting the involvement of subchondral bone degenerative process in cartilage disease progression using advanced conversion pre-clinical imaging modality approach. ( Consultant)
- 2016 - 2019, Skim Geran Penyelidikan Trans-Displin (TRGS)A study to determine the role of multi-modal cellular supplementary support approach in treating cartilage diseases using focal cartilage disease model in rabbit models. ( Consultant)
International
- 2021 - 2023, International FundingAnalysis of the cell growth and protein secretion capacity of foreskin, bladder, and ureter cells with the final aim to improve medical device biocompatibility ( Consultant)
- 2020 - 2022, International FundingAnalysis of The Cell Growth and Protein Secretion Capacity of Foreskin, Bladder and Ureter Cells With The Final Aim To Improve Medical Device Biocompatibility ( Co-Researcher)
CONSULTANCY PROJECT
- Chairman: International Postgraduate Orthopaedic Symposium (Iops), NOCERAL01 Jan 2019 - 01 Jan 2021 (International)
- Honorary Consultant, Spine Research Unit (Sru), Noceral, Spine Research Unit (SRU), NOCERAL01 Jul 2014 - 01 Jul 2017 (National)
- Consultant, Tissue Engineering Laboratory, Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, University of Malaya01 Jul 2014 - 01 Jul 2015 (National)
PAPER PRESENTED
PLENARY SPEAKER
- Biological therapies for articular cartilage repair: from basic research to clinical outcome., The 9th Chinese University of Hong Kong (CUHK) International Symposium on Stem Cell and Regenerative Medicine (9th CUHK SCRM), Chinese University of Hong Kong (International) (10 Nov 2019 - 12 Nov 2019)
INVITED SPEAKER
- The use of mesenchymal stem cells and platelet-derived extracellular vesicles in knee cartilage regeneration: From in vitro experiments to in vivo and clinical treatments, The 2023 International Conference on Future Healthcare and Economic Development, National Cheng Kung University (NCKU), Taiwan (International) (27 Nov 2023 - 01 Dec 2023)
- (1) MSCs (Mesenchymal Stem Cell) - Current Evidence and My Experience; (2) Allogenic MSCs (Mesenchymal Stem Cell) Therapy for Cartilage Repair - Current Evidence and My Experience, The 9th Congress of the Indian Cartilage Society, Indian Cartilage Society (International) (20 Oct 2023 - 21 Oct 2023)
- The use of platelet-derived extracellular vesicles for musculoskeletal tissue regeneration: from basic research to clinical outcome, The M. Kandiah Faculty of Medicine and Health Sciences (MK FMHS) 4th International Scientific Conference 2023, Universiti Tunku Abdul Rahman (UTAR) (International) (18 Sep 2023 - 19 Sep 2023)
- Therapeutic potential of mesenchymal stem cells, perivascular stem cells, and platelet-derived extracellular vesicles in articular cartilage regeneration, Taipei Medical University (TMU) Forum for Cell Therapy and Regenerative Medicine, TMU Research Center for Cell Therapy and Regeneration Medicine (TMU CCTRM) (International) (04 Sep 2023 - 04 Sep 2023)
- Cartilage tissue engineering and osteoarthritis therapy: mesenchymal stem cells, perivascular stem cells, and platelet-derived extracellular vesicles, The 6th International Symposium of Materials in Regenerative Medicine (ISOMRM), International Symposium of Materials in Regenerative Medicine, Taiwan (International) (31 Aug 2023 - 03 Sep 2023)
- The use of platelet-derived extracellular vesicles for musculoskeletal tissue regeneration, The 4th Malaysian Society for Stem Cell Research and Therapy (MSCRT) Stem Cell Symposium 2023, Malaysian Society for Stem Cell Research and Therapy (International) (19 Aug 2023 - 20 Aug 2023)
- Mesenchymal Stem Cell And Platelet-Derived Extracellular Vesicle Therapies For Articular Cartilage Regeneration, Hybrid Symposium: Application of Biotechnology, INTI International University (International) (22 Jun 2023 - 22 Jun 2023)
- The use of perivascular stem cells, mesenchymal stem cells and platelet-derived extracellular vesicles in articular cartilage regeneration regeneration, 52nd Malaysian Orthopaedic Association Annual Scientific Meeting 2023 - Asia Pacific Orthopaedic Research Society (APORS) Track, Malaysian Orthopaedic Association (International) (15 Jun 2023 - 17 Jun 2023)
- Biological roles and therapeutic potential of perivascular stem cells, mesenchymal stem cells and platelet-derived extracellular vesicles in articular cartilage regeneration, 2023 Annual Conference of Formosa Association Regenerative Medicine (FARM), Formosa Association Regenerative Medicine, Taiwan (International) (25 Mar 2023 - 25 Mar 2023)
- (1) The Changes in Tibial Plateau Articular Cartilage and Subchondral Bone Lesion in Human Osteoarthritis Knee ; (2) Augmented MF- The Science and its Results, The 8th Congress of Indian Cartilage Society (ICS) and 7th Congress of Asian Cartilage Repair Society (ACRS), ACRS and ICS (International) (15 Dec 2022 - 17 Dec 2022)
- Platelet-derived extracellular vesicles in treating knee osteoarthritis: in vitro characterisation and clinical outcomes, The 44th Singapore Orthopaedic Association (SOA) Annual Meeting, in conjunction with the 2022 ASEAN Orthopedic Association (AOA) Annual Congress, ASEAN Society for Sports Medicine and Arthroscopy (ASSA) Congress and Academic Congress of the Asian Shoulder Elbow Association (ACASEA) Meeting, Singapore Orthopaedic Association (SOA) (International) (07 Dec 2022 - 10 Dec 2022)
- Mesenchymal stem cell and platelet-derived extracellular vesicle therapies for articular cartilage regeneration: from basic research to clinical outcome, The 3rd International Symposium on Stem Cells and Regenerative Medicine: with a Focus on Extracellular Vesicles , MashhadStemCells, ACECR-Khorasan Razavi, Ferdowsi University of Mashhad, Royan Institute, and Mashhad University of Medical Sciences. (International) (01 Jun 2022 - 02 Jun 2022)
- Mechanical compression controls the biosynthesis of human osteoarthritic chondrocytes in vitro, International Orthopaedic Postgraduate Symposium (IOPS) on December 5th, 2020 (Saturday), NOCERAL, MOA, APORS (International) (05 Dec 2020 - 05 Dec 2020)
- The involvement of subchondral bone, fibrocartilage development and mechanical cues in the OA development and progression. , Osteoarthritis Symposium, NOCERAL (National) (24 Aug 2020 - 25 Aug 2020)
- Biological therapies for articular cartilage repair: from basic research to clinical outcome , The 42nd Annual Scientific Meeting of the Singapore Orthopaedic Association, Singapore Orthopaedic Association (International) (31 Oct 2019 - 02 Nov 2019)
- Cell-based therapy for articular cartilage regeneration: from research to clinical application , International Orthopaedic Postgraduate Basic Science Research (IOPS), This symposium was jointly organized between National Orthopaedic Center of Excellence for Research & learning (NOCERAL) and Malaysia Orthopaedic Association (MOA). It was supported by University Malaya Medical Centre (UMMC) and Research Instruments Sdn. Bhd. (International) (30 Apr 2019 - 30 Apr 2019)
- Osteochondral defects: Bone before cartilage? Or other way round?, 20th Asia Pacific Orthopaedic Association Congress, Antalya, Turkey, Sueno Belek Congress Center (International) (10 Apr 2018 - 14 Apr 2018)
- Cell culture, Inaugural Faculty of Medicine & Health Sciences (FMHS) Scientific Meeting, Post-Conference Workshop, Meet the Experts Session: Sharing Experience on Bench Research, Universiti Tunku Abdul Rahman (National) (27 May 2017 - 27 May 2017)
- Mesenchymal stem cells and their application in articular cartilage regeneration: from research to clinical application, Inaugural Faculty of Medicine & Health Sciences (FMHS) Scientific Meeting, Universiti Tunku Abdul Rahman (International) (25 May 2017 - 26 May 2017)
- Applications of Fluorescence & Confocal Imaging, Understanding Fluorescence using Confocal Microscopy, National Orthopaedic Centre of Excellence in Research and Learning (NOCERAL), Department of Orthopaedic Surgery, Faculty of Medicine,University of Malay; Malaysia Orthopaedic Association (MOA); Hi-Tech Instruments (National) (18 May 2017 - 18 May 2017)
- The Relationship Between Hyaline Cartilage And Subchondral Bone Lesions In The Patients With Knee Osteoarthritis, 3rd Malaysian Arthroscopy Society (MAS) Scientific Meeting and 3rd Asian Cartilage Research Society (ACRS) Meeting, 3rd Malaysian Arthroscopy Society ASM 2015 & 3rd Asian Cartilage Research Society Meeting (International) (29 Oct 2015 - 31 Oct 2015)
- The cartilage: from mesenchymal stem cells to chondrocytes, 4th UTAR Seminar on Stem Cell and iPSC Research (2015) (4th SCiP); 1st Joint UTAR-UST (Taiwan) Symposium on Stem Cell Research , Universiti Tunku Abdul Rahman & University System Taiwan (International) (03 Aug 2015 - 04 Aug 2015)
- An investigation to determine the chondrogenic differentiation potential of bone marrow and peripheral blood-derived mesenchymal stem cells in vitro, The 3rd UTAR Seminar on Stem Cell and iPSC Research (2013): Basic and Translational Aspects, UTAR Sg. Long campus (International) (06 Dec 2013 - 06 Dec 2013)
EVENT ORGANISER
- Organising Committee, 7th ASEAN Flow Cytometry Workshop, University of Malaya, International Society for the Advancement of Cytometry (ISAC), NOCERAL, MOA  (International) (21 Oct 2019 - 23 Oct 2019)
- Organising Committee, Clean Room & Lab Safety Seminar on 22-23 Aug 2019, NOCERAL (University) (22 Aug 2019 - 23 Aug 2019)
- Organising Chairperson of IOPS, International Orthopaedic Postgraduate Basic Science Research (IOPS) , This symposium was jointly organized between National Orthopaedic Center of Excellence for Research & learning (NOCERAL) and Malaysia Orthopaedic Association (MOA). It was supported by University Malaya Medical Centre (UMMC) and Research Instruments Sdn. Bhd (International) (30 Apr 2019 - 30 Apr 2019)
- Pathology, Biomaterials and Biomechanics, Principles of Surgery, Orthopaedics Specialty Committee (OSC) Part 1 Examination Preparatory Courses (2018) , NOCERAL (National) (09 Jul 2018 - 10 Jul 2018)
- Physiology and Applied Clinical Physiology, Orthopaedics Specialty Committee (OSC) Part 1 Examination Preparatory Courses (2018) , NOCERAL (National) (02 Jul 2018 - 03 Jul 2018)
- Anatomy and Applied Surgical Anatomy, Orthopaedics Specialty Committee (OSC) Part 1 Examination Preparatory Courses (2018) , NOCERAL (National) (04 Jun 2018 - 05 Jun 2018)
- Pathology, Biomaterials and Biomechanics, Principles of Surgery, Conjoint Board of Orthopaedic (CBO) Part 1/ Basic Sciences Examination (BSE) Preparatory Course, NOCERAL (National) (05 Mar 2018 - 07 Mar 2018)
- Physiology and Applied Clinical Physiology, Conjoint Board of Orthopaedic (CBO) Part 1/ Basic Sciences Examination (BSE) Preparatory Course, NOCERAL (National) (05 Feb 2018 - 06 Feb 2018)
- Anatomy and Applied Surgical Anatomy, Conjoint Board of Orthopaedic (CBO) Part 1/ Basic Sciences Examination (BSE) Preparatory Course , NOCERAL (National) (08 Jan 2018 - 09 Jan 2018)
- Pathology, Biomaterials and Biomechanics, Principles of Surgery, Conjoint Board of Orthopaedic (CBO) Part 1/ Basic Sciences Examination (BSE) Preparatory Course, NOCERAL (National) (18 Sep 2017 - 20 Sep 2017)
- Physiology and Applied Clinical Physiology, Conjoint Board of Orthopaedic (CBO) Part 1/ Basic Sciences Examination (BSE) Preparatory Course, NOCERAL (National) (21 Aug 2017 - 22 Aug 2017)
- Anatomy and Applied Surgical Anatomy, Conjoint Board of Orthopaedic (CBO) Part 1/ Basic Sciences Examination (BSE) Preparatory Course, NOCERAL (National) (17 Jul 2017 - 18 Jul 2017)
- Applications of Fluorescence & Confocal Imaging, Understanding Fluorescence using Confocal Microscopy, National Orthopaedic Centre of Excellence in Research and Learning (NOCERAL), Department of Orthopaedic Surgery, Faculty of Medicine,University of Malay; Malaysia Orthopaedic Association (MOA); Hi-Tech Instruments (National) (18 May 2017 - 18 May 2017)
- The Relationship Between Hyaline Cartilage And Subchondral Bone Lesions In The Patients With Knee Osteoarthritis, Workshop on High-Resolution Peripheral Quantitative Computed Tomography: Techniques, Methodology and Clinical Applications, National Orthopaedic Centre of Excellence in Research and Learning (NOCERAL), Department of Orthopaedic Surgery, Faculty of Medicine,University of Malay; Malaysia Orthopaedic Association (MOA); Hi-Tech Instruments (International) (13 Apr 2016 - 14 Apr 2016)
ORAL PRESENTER
- Characteristics, biological function and clinical application of platelet-derived extracellular vesicles for the repair of knee osteoarthritis, The 2023 Asia Pacific Societies for Extracellular Vesicles (APSEV) Conference, Taiwan Society for Extracellular Vesicles (TSEV), International Organizing Committee of 2023 APSEV Conference (International) (31 Mar 2023 - 02 Apr 2023)
- Mechanical compression enhances cartilage matrix synthesis of the expanded osteoarthritic chondrocytes, International Cartilage Repair Society (ICRS) Heritage Summit 2017, Gothenburg, Sweden. , International Cartilage Repair Society (ICRS)  (International) (29 Jun 2017 - 01 Jul 2017)
- The changes in molecular regulation, mechanostimulation and biosynthesis of articular cartilage in the human osteoarthritic knee, The 4th Asian Cartilage Repair Society Congress 2016 and the 19th China National Arthroscopy Skill Course, The 4th Asian Cartilage Repair Society Congress 2016 and the 19th China National Arthroscopy Skill Course  (International) (14 Oct 2016 - 17 Oct 2016)
- The relationship between hyaline cartilage and subchondral bone lesions in the patients with knee osteoarthritis, 20th International Bone Densitometry Workshop (IBDW 2014), Hong Kong, 20th International Bone Densitometry Workshop (IBDW 2014) & The Chinese University of Hong Kong (International) (13 Oct 2014 - 17 Oct 2014)
- Isolation of Mesenchymal Stem Cells from Bone Marrow & Peripheral Blood: The Potential Sources for Cartilage Regeneration, Post-graduate Research Award Day , Scientific Meeting of the Malaysian Society for Molecular Biology and Biotechnology (MSMBB) (National) (30 Oct 2012 - 30 Oct 2012)
- Characterization of Human Blood-Derived MesenchymalStem Cells and Their Potential for Chondrogenic Differentiation, Annual Meeting of the Orthopaedic Research Society, ORS (International) (13 Jan 2011 - 16 Jan 2011)
- Analysis of Chondrogenic Mesenchymal Stem Cells as Potential Biomarkers for Cartilage Cells, 40th Malaysian Orthopaedic Assciation Annual General Meeting / Annual Scientific Meeting, Malaysian Orthopaedic Association; Asian International Federation of Foot & Ankle Societies  (National) (20 May 2010 - 22 May 2010)
- Histological changes in chronic allograft Nephropathy, The International Student Congress of Medical Sciences (ISCOMS) Research Fellowship, University Medical Center Groningen (UMCG), The Netherlands (International) (08 Jun 2009 - 19 Jun 2009)
- TGF-beta3 and BFGF induction of in vitro chondrogenesis in human bone marrow and blood-derived mesenchymal stem cells, The 12th Biological Sciences Graduate Congress 2007 , 12th BSGC 2007 Committee, Institute of Biological Sciences, Faculty of Science, University of Malaya, Malaysia; In Collaboration With: National University of Singapore; Chulalongkorn Uni., Bangkok  (National) (17 Dec 2007 - 19 Dec 2007)
- Pencirian genom Lates calcarifer dengan kaedah penjujukan rawak, 3rd Postgraduate Presentation (Kolokium Siswazah Pertama), Faculty of Science and Technology, National University of Malaysia (UKM)  (University) (30 Jul 2003 - 31 Jul 2003)
POSTER PRESENTER
- MICROSTRUCTURAL ANALYSIS OF SUBCHONDRAL BONE AND HYALINE CARTILAGE IN THE PATIENTS WITH KNEE OSTEOARTHRITIS, The 51st Malaysian Orthopaedic Association Annual Scientific Meeting 2022, Malaysian Orthopaedic Association (National) (09 Jun 2022 - 11 Jun 2022)
- Relationship between articular cartilage and subchondral bone lesion in human osteoarthritis, 45th Malaysian Orthopaedic Association Annual General Meeting / Annual Scientific Meeting, Malaysian Orthopaedic Association and the Organising Committee (National) (22 May 2015 - 24 May 2015)
- Human blood-derived mesenchymal stem cells: An alternative cell therapy to repair cartilage defects (Poster abstract has been selected for the final top 8 under Health & Translational Medicine Research Cluster), University of Malaya Researchers' Conference 2013 (UMRC 2013): Advancing Frontiers through Research on Grand Challenges , University of Malaya  (National) (19 Nov 2013 - 20 Nov 2013)
- Regulatory Gene Expression in the Chondrogenesis of Adult Mesenchymal Stem Cells, 56th Annual Meeting of the Orthopaedic Research Society, Orthopaedic Research Society (International) (06 Mar 2010 - 09 Mar 2010)
- Microarray-based discovery of potential genes involved in chondrogenesis of mesenchymal stem cells derived from human bone marrow., 2nd Tissue Engineering and Regenerative Medicine, TERMIS , Korea Tissue Engineering and Regenerative Medicine Society (International) (31 Aug 2009 - 03 Sep 2009)
- Human blood-derived mesenchymal stem cells: A new potential cell therapy for cartilage regeneration., 2nd Tissue Engineering and Regenerative Medicine, TERMIS , Korea Tissue Engineering and Regenerative Medicine Society (International) (31 Aug 2009 - 03 Sep 2009)
- Comparative characteristics of mesenchymal stem cell-driven chondrocytes from human blood and bone marrow: A new potential cell therapy to repair cartilage defects, International Society for Stem Cell Research (ISSCR): 7th Annual Meeting (The World s Premier Stem Cell Research Event), International Society for Stem Cell Research (ISSCR)  (International) (08 Jul 2009 - 11 Jul 2009)
- A new potential cell therapy using peripheral blood-derived mesenchymal stem cells to repair cartilage defects, The International Student Congress of Medical Sciences (ISCOMS), University Medical Center Groningen (UMCG) (International) (02 Jun 2009 - 05 Jun 2009)
- Gene expression profile analysis of mesenchymal stem cells and mesenchymal stem cell-driven chondrocytes: To find novel human marker genes for cartilage cells., Combined Meeting of (i) 39th Malaysian Orthopaedic Association Annual General Meeting / Annual Scientific Meeting & (ii) WENMISS 2009 Annual Congress of The World Society for Endoscopic, Navigated & Minimal Invasive Spine Surgery, Malaysian Orthopaedic Association; World Society for Endoscopic, Navigated & Minimal Invasive Spine Surgery  (National) (21 May 2009 - 23 May 2009)
- Identification and validation for chondrogenic differentiation of human mesenchymal stem cell in three dimensional scaffolds by quantitative real-time PCR, Combined Meeting of (i) 39th Malaysian Orthopaedic Association Annual General Meeting / Annual Scientific Meeting & (ii) WENMISS 2009 Annual Congress of The World Society for Endoscopic, Navigated & Minimal Invasive Spine Surgery:, Malaysian Orthopaedic Association; World Society for Endoscopic, Navigated & Minimal Invasive Spine Surgery  (National) (21 May 2009 - 23 May 2009)
- Factor which contribute to the success rates of mesenchymal stem cells (MSCs) isolation and expansion: A cross-sectional study, Combined Meeting of (i) 39th Malaysian Orthopaedic Association Annual General Meeting / Annual Scientific Meeting & (ii) WENMISS 2009 Annual Congress of The World Society for Endoscopic, Navigated & Minimal Invasive Spine Surgery, Malaysian Orthopaedic Association; World Society for Endoscopic, Navigated & Minimal Invasive Spine Surgery  (National) (21 May 2009 - 23 May 2009)
- Comparing the suitability of SDS-PAGE and experion automated electrophoresis systems for protein extraction from bone marrow mesenchymal stem cells (BM-MSCs) using different lysis buffer solutions., Combined Meeting of (i) 39th Malaysian Orthopaedic Association Annual General Meeting / Annual Scientific Meeting & (ii) WENMISS 2009 Annual Congress of The World Society for Endoscopic, Navigated & Minimal Invasive Spine Surgery, Malaysian Orthopaedic Association; World Society for Endoscopic, Navigated & Minimal Invasive Spine Surgery  (National) (21 May 2009 - 23 May 2009)
- Identification of human bone marrow derived mesenchymal stem cells (MSCS) for studies of chondrogenic differentiation, The 13th Biological Sciences Graduate Congress, Singapore, National University of Singapore; University of Malaya; Chulalongkorn University  (International) (15 Dec 2008 - 17 Dec 2008)
- Comparative Characteristics of mesenchymal stem cells derived from human and rabbit bone marrow, The 3rd Asian Federation of Laboratory Animal Science Association (AFLAS) Congress and The 8th Chinese Association for Laboratory Animal Sciences (CALAS) Annual Meeting, China, Asian Federation of Laboratory Animal Science Association (AFLAS); Chinese Association for Laboratory Animal Sciences (CALAS)  (International) (27 Sep 2008 - 29 Sep 2008)
- Human blood-derived progenitor cells: a new potential cell therapy to repair cartilage defects, Combined Meeting of (1) 28th Asean Orthopaedic Association Congress (2) 38th Malaysian Orthopaedic Association AGM/ASM (incorporating the 4th Instructional Course of the American Academy of Orthopaedic Surgeons), Asean Orthopaedic Association; American Academy of Orthopaedic Surgeons; Malaysian Orthopaedic Association  (National) (26 Jun 2008 - 29 Jun 2008)
- Chondrogenic potency of human bone marrow derived mesenchymal stem cells (MSCs): Flow cytometry and gene expression analysis, Combined Meeting of (1) 28th Asean Orthopaedic Association Congress (2) 38th Malaysian Orthopaedic Association AGM/ASM (incorporating the 4th Instructional Course of the American Academy of Orthopaedic Surgeons), Asean Orthopaedic Association; American Academy of Orthopaedic Surgeons; Malaysian Orthopaedic Association  (National) (26 Jun 2008 - 29 Jun 2008)
- In vitro study of human amniotic membrane as a chondrocyte carrier, The 12th Biological Sciences Graduate Congress 2007 , 12th BSGC 2007 Committee, Institute of Biological Sciences, Faculty of Science, University of Malaya, Malaysia. In Collaboration With: National University of Singapore; Chulalongkorn Uni., Bangkok  (National) (17 Dec 2007 - 19 Dec 2007)
- In vitro chondrogenesis of mesenchymal stem cells derived from human bone marrow and blood using three-dimensional scaffolds. , International Conference on Cellular & Molecular Bioengineering (ICCME), Nanyang Technological University (NTU), Singapore (International) (10 Dec 2007 - 12 Dec 2007)
- Chondrogenic mesenchymal stem cells seeding on amniotic scaffold, International Conference on Cellular & Molecular Bioengineering (ICCME), Nanyang Technological University (NTU), Singapore  (International) (10 Dec 2007 - 12 Dec 2007)
- Isolation and induction of chondrogenesis in mesenchymal stem cells from human bone marrow and blood, 37th Malaysian Orthopaedics Association Annual Meeting / Annual Scientific Meeting & 14th International IMLAS (International Musculoskeletal Laser Society) Congress, Malaysian Orthopaedics Association; International Musculoskeletal Laser Society  (National) (17 May 2007 - 20 May 2007)
- Repair of rabbit focal cartilage defects with autologous chondrocytes embedded in alginate, Kuala Lumpur International Conference on Biomedical Engineering 2006 (Biomed 2006), Department of Biomedical Engineering, University of Malaya, Malaysia; Department of Biomedical Engineering, Inje University, Korea; Malaysian Society of Medical and Biological Engineering  (International) (11 Dec 2006 - 14 Dec 2006)
- Characterization of the sea bass (Lates calcarifer) genome by random sequencing, 2nd International Conference on Bioinformatics (InCoB 2003), Ministry of Science, Technology & the Environment (MOSTE), Malaysia (International) (08 Sep 2003 - 10 Sep 2003)
- Construction and characterisation of a genomic library from sea bass (Lates calcarifer)., National Fisheries Symposium 2003, Malaysia, Fisheries Research Institute, Marine Fish Production & Research Centre, Malaysia  (National) (18 Feb 2003 - 20 Feb 2003)
- Characterisation of the sea bass (Lates calcarifer) genome by random sequencing., 27th Annual Conference of The Malaysian Society for Biochemistry & Molecular Biology: Frontiers in Biotechnology, The Malaysian Society for Biochemistry & Molecular Biology (National) (07 Oct 2002 - 07 Oct 2002)
PRESENTER
- Human blood-derived mesenchymal stem cells: a new potential cell therapy to repair cartilage defects, Research, Invention & Innovation Expo 2009, University of Malaya (University) (13 Jan 2009 - 15 Jan 2009)
OTHERS
- I was the supervisor of the master student, Dr. Nik Aizah Nabilla Bt Faheem, who has been granted for the Mahmood Merican Best Master Thesis Award. Her presentation entitled: A study on early progressive alterations of subchondral bone and articular cartilage in the rat anterior cruciate ligament transection model of osteoarthritis, 48th Malaysia Orthopaedic Association (MOA) Congress, MOA (International) (09 May 2018 - 12 May 2018)
- Chairperson of Asian Cartilage Research Society (ACRS): session 2, 3rd Malaysian Arthroscopy Society (MAS) Scientific Meeting and 3rd Asian Cartilage Research Society (ACRS) Meeting, 3rd Malaysian Arthroscopy Society (MAS) Scientific Meeting and 3rd Asian Cartilage Research Society (ACRS) Meeting - Organizing Committee (International) (29 Oct 2015 - 31 Oct 2015)
ACADEMIC/PROF. SERVICES
Evaluation
- (2024) An Official Member of Online Academic Editor of World Journal of Stem Cells, International, (Reviewer)
- (2023) Preliminary Jury for The Loreal-Unesco for Women in Science Malaysia 2023, National, (External Evaluator)
- (2023) Panel Reviewer for The Umsc Ca.R.E Fund Research Grant (Umsc-Rg) & Dato' Mahmood Merican Medical Research Grant (Mmrg) 2023., University, (External Evaluator)
- (2023) To Evaluate The Report of Sara Izzati's Final Year Project, University, (External Examiner)
- (2023) To Evaluate The Oral Presentation by Sara Izzati's, for Her Final Year Project, University, (External Evaluator)
- (2022) Examiner for The Candidature Defence: Hwong Chia Shing (17219026/1), Phd Candidate, University, (External Examiner)
- (2022) Examiner for The Proposal Defence - Nursyauqina Sofree (S2130168/1), Master Candidate, University, (External Examiner)
- (2022) Panel Temu Duga MBBS Saluran Terbuka Universiti Malaya (Satu), University, (Internal Assessor)
- (2022) Invited Reviewer for The Abstracts of The International Combined Orthopaedic Research Society Meeting, World Congress Orthopaedic Research, Edinburgh, UK, 7-9 Sept 2022 (Icors),, International, (Reviewer)
- (2022) Examiner for The Candidature Defence - Khalishah Yusri (17219578), University, (External Examiner)
- (2022) Phd Confirmation/Candidature Deference - Andy Lim Shing Seng (17278830), University, (Internal Examiner)
- (2021) Judge for Mompes 1st Scientific Symposium 2021, National, (External Evaluator)
- (2021) External Evaluator for The Iirg Researcg Grant, University, (External Evaluator)
- (2021) Invited Reviewer to Review The Manuscript from: Journal of Health and Translational Medicine, National, (Reviewer)
- (2021) Invited Reviewer for The Manuscript from: Bioengineered, International, (Reviewer)
- (2021) Invited Reviewer to Review Manuscript from: Scientific Reports, International, (Reviewer)
- (2021) Invited Reviewer to Review Manuscript from: Journal of Visualized Experiments, International, (Reviewer)
- (2021) Invited Reviewer for The Manuscript from: Malaysian Journal of Medicine and Health Sciences, International, (Reviewer)
- (2021) External Evaluator for The Proposal Defence by a Master Candidate (Khalishah Yusri), University, (External Evaluator)
- (2020) Examiner for the thesis of Nur Atikah binti Suhaimi , (Internal Examiner)
- (2020) Examiner for the PhD proposal defence by Chan Yi Wei - Investigations into the poor neutralization efficacy of cobra antivenom towards lethal cobra neurotoxins through in vitro, in vivo and in silico studies , (Internal Examiner)
- (2020) Examiner for the final year project presentation by Nur Atikah binti Suhaimi , (Internal Examiner)
- (2019) Reviewer for Journal of Pediatric Infectious Diseases. (International) , (Reviewer)
- (2019) Reviewer for Sains Malaysiana. (International) , (Reviewer)
- (2019) As an invited Industry Panel (Examiner), for ENGENIUS 2019 (a conference which involved about 500 final year students), on 21st & 23 May 2019, at Faculty of Engineering, University of Malaya (University), (invited Industry Panel (Examiner))
- (2019) As a thesis examiner, for the candidate Dr. Liew Hoe Chin (MGI 160019). A thesis submitted for partial fulfillment for the degree of master of orthopedic surgery. Thesis title: The effects of Eurycoma longifolia and Labisia pimilia on bone density of oophorectomised female rats. (Department), (Internal Examiner)
- (2018) Reviewer for Stem Cells International journal , (Reviewer)
- (2018) Reviewer for Archives of Bone and Joint Surgery , (Reviewer)
- (2018) Reviewer for The Journal of Health and Translational Medicine (JUMMEC), (Reviewer)
- (2018) Jury panel: L Or al-UNESCO For Women in Science Award 2018 (Malaysia)
- (2018) Reviewer: Japan Medical Innovation Program, Kyushu University, Japan , (Reviewer)
- (2017) Internal examiner: Dr Bong Chin Pei (MGI140016, Master in Orthopaedic Surgery); Department of Orthopaedic Surgery, Faculty of Medicine, University of Malaya,50603 Kuala Lumpur. Title of Thesis: Effects of Preoperative Education on Pateient Satisfaction after Total Knee Arthroplasty Reviewed thesis in September 2017 , (Internal Examiner)
- (2017) Reviewer: Immunological Investigations, (Reviewer)
- (2017) Reviewer: Journal of Tissue Viability , (Reviewer)
- (2016) Internal Examiner: Yong Kar Wey (KHA130037, Ph.D. candidate). Department of Biomedical Engineering, Faculty of Engineering, University of Malaya,50603 Kuala Lumpur. Viva: 2.30 pm, 16 June 2016 (Thursday), Dean Meeting Room , Level 4, Block L, Engineering Tower. Title of Thesis: Optimization on cryopreservation condition of human adiposed-derive stem cells and their application in cardiac fibrosis therapy. , (Internal Examiner)
- (2016) Reviewer: Japan Medical Innovation Program, Kyushu University, Japan , (Reviewer)
- (2015) Reviewer: Journal of Orthopaedic Research , (Reviewer)
Contribution to external organisation
- (2020) Organising Chairperson, International Orthopaedic Postgraduate Symposium (IOPS), International
- (2020) 11. Basic Science/Orthopaedics Preparatory Courses: Anatomy and Applied Surgical Anatomy, NOCERAL, National
- (2020) 12. Basic Science/Orthopaedics Preparatory Courses: Physiology and Applied Clinical Physiology , NOCERAL, National
- (2020) 14. Basic Science/Orthopaedics Preparatory Courses: Physiology - How to prepare challenging viva questions, NOCERAL, National
- (2020) 13. Basic Science/Orthopaedics Preparatory Courses: Pathology, Biomaterials and Biomechanics, Principles of Surgery , NOCERAL, National
- (2019) As an Invited oral and thesis examiner for MIC 4005 Research in Biomedical Science, Department of Biomedical Sciences, Faculty of Medicine, University of Malaya, University
- (2019) 3. Orthopaedics Specialty Committee (OSC) Part 1 Examination Preparatory Courses (4 January 2019, Friday): Course C: Pathology, Biomaterials and Biomechanics, Principles of Surgery, NOCERAL, National
- (2019) 4. Orthopaedics Specialty Committee (OSC) Part 1 Examination Preparatory Courses (15 July 2019, Monday): Part 1a: Anatomy and Applied Surgical Anatomy, NOCERAL, National
- (2019) 2. Orthopaedics Specialty Committee (OSC) Part 1 Examination Preparatory Courses (3 January 2019, Thursday): Course B: Physiology and Applied Clinical Physiology , NOCERAL, National
- (2019) 10. Orthopaedics Specialty Committee (OSC) Part 1 Examination Preparatory Courses (24-25 September 2019, Tuesday-Wednesday): Physiology: How to prepare challenging viva questions , NOCERAL, National
- (2019) 5. Orthopaedics Specialty Committee (OSC) Part 1 Examination Preparatory Courses (16 July 2019, Tuesday): Part 1b: Physiology and Applied Clinical Physiology, NOCERAL, National
- (2019) 6. Orthopaedics Specialty Committee (OSC) Part 1 Examination Preparatory Courses (17 July 2019, Wednesday): Part 1c: Pathology, Biomaterials and Biomechanics, Principles of Surgery, NOCERAL, National
- (2019) 9. Orthopaedics Specialty Committee (OSC) Part 1 Examination Preparatory Courses (21 August 2019, Wednesday): Part 2c: Pathology, Biomaterials and Biomechanics, Principles of Surgery, NOCERAL, National
- (2019) 1. Orthopaedics Specialty Committee (OSC) Part 1 Examination Preparatory Courses (2 January 2019, Wednesday): Course A: Anatomy and Applied Surgical Anatomy, NOCERAL, 2019, (National), NOCERAL, National
Contribution to event
- (2023) Moderator: Advancements in Scaffolds -The 9th Congress of The Indian Cartilage Society, International, (Panelist/Moderator)
- (2023) Chairperson: Bone Repair – Orthopaedic Research Moa Apors Track, International, (Panelist/Moderator)
- (2022) Organising Chairperson of The 3rd International Orthopaedic Postgraduate Symposium (Iops3), International, (Event Organiser)
- (2021) Invited Speaker: Comparing The Therapeutic Potential of Stem Cells and Their Secretory Products in Regenerative Medicine and Osteoarthritis, International, (Panelist/Moderator)
- (2021) Invited Speaker for The Fundamental Primary Cell Culture Workshop, National, (Panelist/Moderator)
- (2021) Coordinator for The Intensive Physiology Exam Preparatory Workshop for Trainees of Orthopaedic Surgery October 2021, National, (Event Coordinator)
- (2021) Scientific Committee (Preparatory Course for Entrance Exam) for The Asia Pacific Orthopaedic Association Congress, International, (Event Organiser)
- (2021) Invited Speaker: Ensuring The Optimum and Realistic Study Model/Design, International, (Panelist/Moderator)
- (2021) Coordinator for The Webinar: Pathology, Biomaterials and Biomechanics, Principles of Surgery, National, (Event Coordinator)
- (2021) Coordinator for The Webinar: Physiology and Applied Clinical Physiology, National, (Event Coordinator)
- (2021) Coordinator for The Webinar: Anatomy and Applied Surgical Anatomy, National, (Event Coordinator)
SUPERVISION
Postgraduate Student
-
(2024) Biological properties of human platelet-derived extracellular vesicles and their potential clinical utility to treat osteoarthritis, NUR HIDAYAH HASSAN
-
(2024) Investigating Effects of Moderate Physical Exercise on Cartilage Degeneration, Early Subchondral Bone Remodeling and Blood miRNA Expression Profiling at The Tibial Plateau of Anterior Cruciate Ligament Transected Osteoarthritis Rat Model, NURIZZATY KHAIRI BINTI MOHAMED
-
(2024) INVESTIGATING THE ROLE OF PERIPHERAL BLOOD MIRNAS AS POTENTIAL DIAGNOSTIC AND THERAPEUTIC TARGETS IN TREATING OSTEOARTHRITIS., ONG HUI LING
-
(2024) REGENERATION OF FULL-THICKNESS FOCAL CARTILAGE DEFECT OF THE KNEE IN RABBIT MODEL USING ALLOGENEIC ORIGINS OF PERIPHERAL BLOOD-DERIVED MESENCHYMAL STROMAL CELLS AND PLATELET-RICH PLASMA, RUFAIDAH BINTI OTHMAN
-
(2023) The Safety and Efficacy of Intra-articular Injection of Combined Autologous Peripheral Blood-Derived Mesenchymal Stem Cells (PB-MSC) with Platelet-Derived Extracellular Vesicles (PEV) in the Treatment of Knee Osteoarthritis: Randomized Controlled Clinical Trial (Phase I & II), CHOONG WAI KWONG
-
(2020) Biological properties of human platelet-derived extracellular vesicles and their potential clinical utility to treat osteoarthritis, Nur Hidayah Hassan
-
(2017) Involvement of potential pathways in the healing of focal cartilage defect in rabbits revealed by proteomic analysis, RUFAIDAH OTHMAN
-
(2017) SURFACE MODIFICATION OF YTTRIA-STABILISED ZIRCONIA AT NANOSCALE FOR IN VITRO STUDY, SOON GINNY
-
(2014) Mechanism study of selk-assembled nanostructures in miscut yttria-stabilised zirconia(YSZ) and its potential extension to other material system, SOON GINNY
-
(2024) EFFECTS OF THE HUMAN PLATELET-RICH PLASMA, PLATELET-DERIVED EXTRACELLULAR VESICLES AND PLATELET LYSATE ON THE EXPANDED OSTEOARTHRITIC CHONDROCYTES., ANAND CHANDRASEKARAN
-
(2024) A STUDY COMPARING THE STEMNESS, CHONDROGENIC DIFFERENTIATION AND DEGENERATED CARTILAGE REPAIR POTENTIAL BETWEEN PERIVASCULAR STEM CELLS AND MESENCHYMAL STROMAL CELLS IN RATS, SHAN XIAOLONG
-
(2022) Identification of Crucial microRNAs Expressed in Patients with End-Stage Knee Osteoarthritis, THAM MEI LYN
-
(2022) The Effects of Unilateral Osteoarthritis and its Treatment on the Contralateral Knee Using a Rat Anterior Cruciate Ligament Transection Model, Nurul Natasha Binti Mohd Anuar
-
(2020) Alterations of non-operated knees following stem cell therapies treatment for the rat anterior cruciate ligament transection model of osteoarthritis, Nurul Natasha
-
(2020) ISOLATION AND CHARACTERIZATION OF RABBIT PLATELET- DERIVED EXTRACELLULAR VESICLES (P-EV), WAN NURASLIZA BINTI WAN ANOWAR
-
(2018) Isolation and characterization of rabbit platelet-derived extracellular vesicles (P-EV), Wan Nurasliza binti Wan Anowar
-
(2018) Intra-articular injection peripheral blood-derived mesenchymal stem cells, platelet-derived extracellular vesicles and bone marrow concentrate for cartilage repair and regeneration, LIEW TAT WEN STEVEN
-
(2017) Functional properties to distinguish perivascular stem cells from other mesenchymal stromal cells in cartilage tissue engineering, SHAN XIAOLONG
-
(2016) The Nutraceutical Potential of Curcumin in Reducing The Progression of Osteoarthritis: Alterations in Subchondral Bone and Articular Cartilage Properties in The Rat Anterior Cruciate Ligament Transection Model of Post-Traumatic Osteoarthritis, Ahmad Amin bin Hudi
-
(2016) The effect of intraarticular supplementation of platelet rich concentrates in the treatment of focal cartilage defect in rabbits, Ahmad Ikhwan Bin Mohd Sharfuddin
-
(2016) High-resolution imaging of bone and joint architecture in rheumatoid arthritis, Syarifah Nor Amirah Bt Syed Abdul Latiff Alsagoff
-
(2016) A Study To Determine The Efficacy Of Intra-articular Injection Of Platlet Derived Extracellular Vesicles In Treating Patients With Mild Or Moderate Osteoarthritis, Jonas Fernandez
-
(2014) Effect of the Mechanical Loading on the Cellular Matrices of Expanded Osteoarthritic Chondrocytes, Ponnurajah Panjavarnam
-
(2013) A Study on Early Progressive Alterations of Subchondral Bone and Articular Cartilage in the Rat Anterior Cruciate Ligament Transection Model of Osteoarthritis, NIK AIZAH NABILLA BT FAHEEM
TEACHING
Master
- (2023) MOB7004 - Advanced Regenerative Medicine
- (2023) MOB7007 - Advance Tools in Regenerative Medicine
- (2023) MOB7005 - Cell Based Therapy and Regulation in Regenerative Medicine
- (2023) MOB7001 - Research Methodology
- (2023) MOB7003 - Stem Cell and Tissue Engineering
- (2022) MOB7004 - Advanced Regenerative Medicine
- (2022) MOB7007 - Advance Tools in Regenerative Medicine
- (2022) MOB7005 - Cell Based Therapy and Regulation in Regenerative Medicine
- (2022) MOB7001 - Research Methodology
- (2022) MOB7003 - Stem Cell and Tissue Engineering
- (2021) MOB7007 - Advance Tools in Regenerative Medicine
- (2021) MOB7005 - Cell Based Therapy and Regulation in Regenerative Medicine
- (2021) MOB7001 - Research Methodology
- (2021) MOB7003 - Stem Cell and Tissue Engineering
- (2018) MOB7003 - Stem Cell and Tissue Engineering
- (2018) MOB7005 - Cell Based Therapy and Regulation in Regenerative Medicine
- (2018) NIL - Supervision: Master by Research
- (2018) NIL - Supervision: Master of Orthopaedic Surgery
- (2018) NIL - Supervision: Phd
- (2017) NIL - Orthopaedic Research Training Program
- (2017) NIL - Supervision: Master of Orthopaedic Surgery
- (2017) NIL - Supervision: Phd
PATENT/IPR
- Platelet-derived extracellular vesiclesFiled/Pending (National)
- Human Blood-Derived Mesenchymal Stem Cells to Repair Cartilage DefectPatent (National)
SOCIAL RESPONSIBILITY ACTIVITIES
- Examiner: Final Year Project Presentation, Nur Atikah Suhaimi The Effects of Swietenia Macrophylla Extract of Mesenchymal Stromal Cells Proliferation and Matrix Mineralisation, (08 May 2020 - 08 May 2020)
- Coordinator for Prof. Byoung Hyun Min (Ajou University) and Atems Company (Korea) to Conduct a Clinical Trial Using a-Paste to Repair The Full Thick Articular Cartilage Defect of The Knee., (30 Aug 2019 - 31 Dec 2021)
- Coordinator for Dr. Mattias Larsson''S Project: Fiber Density of Collagen Grafts Impacts Rabbit Urethral Regeneration, from Department of Pediatrics, Centre Hospitalier Universitaire Vaudois (Chuv), Lausanne, Switzerland., (19 Aug 2019 - 31 Dec 2020)
- Invited Chairperson for The Orthopaedic Research Session in The 49th Malaysian Orthopaedic Association Annual Scientific Meeting (Moa Asm) 2019, 2nd to 4th May 2019. Venue: Hilton + Le Meridien Kuala Lumpur, Malaysia., (02 May 2019 - 04 May 2019)
- As a Chairman, for The Wednesday Morning Symposium, 13th February 2019 (Wednesday), 8:00 Am - 9:00 Am, At Clinical Auditorium, Level 2, Faculty of Medicine, University of Malaya. The Presentation Was Given by Dr Nik Aizah Nabilla Bt Faheem. Her Presentation Title: Platelet-Derived Extracellular Vesicles (P-Ev): An Innovation of Platelet-Rich Plasma (Prp). (Faculty), (13 Feb 2019 - 13 Feb 2019)
- Introduction to Clean Room, At Noceral. Event Organizer, (15 Nov 2018 - 15 Nov 2018)
- 24th Silent Mentor Workshop: (1) to Assist Tissue Harvesting for The Collaborator from Korea, (2) Arrangement for The Tissue Transporting to Korea, (3) Involved in The Initiation Ceremony, Gratitude Ceremony and The Sending Off Ceremony, (23 Oct 2018 - 28 Oct 2018)
- Seminar: Enabling Rnai and Gene Editing, At Noceral. Event Organizer, (28 Sep 2018 - 28 Sep 2018)
- Unleash Your Researchpotential With Advances in Flow Cytometry, At Noceral. Event Organizer, (07 Aug 2018 - 08 Aug 2018)
- Seminar: Pre-Clinical and Phase 1 Clinical Trials in The Cell-Based Therapy and Drug Development, At Ummc, Event Organizer., (26 Feb 2018 - 26 Feb 2018)
- Public Lecture (Noceral): Mesenchymal Stem Cells and Their Application in Articular Cartilage Regeneration: from Research to Clinical Application, (16 Jan 2018 - 16 Jan 2018)
- Coordinator: Noceral Annual Orthopaedic Research Seminar & Workshop, Combined With Asean Ortho[Adic Research Section / Asia Pacific Orthopaedic Research Society and Malaysia Orthopaedic Association, At Datin Ragayah Lecture Hall, Department of Orthopaedic Surgery, University of Malaya. 14-15 December 2017, (14 Dec 2017 - 15 Dec 2017)
- The Certificate of Appreciation is Presented to Dr Chong Pan Pan for Her Notable Contributions in The Malaysia Orthopaedic Association (Moa) Mid-Term Meeting, 9th - 10th December 2017. The Everly, Putrajaya, Kuala Lumpur. (National Level), (09 Dec 2017 - 10 Dec 2017)
- Internal Auditor for Cell and Tissue Transplantation Laboratory (Cttl), Ummc. it a Laboratory Which Follows Processing Based On Good Manufacturing Practice (Gmp)., (06 Nov 2017 - 07 Nov 2017)
- Blood Donation Program: Certificate of Appreciation is Awarded to Chong Pan Pan for Meritorious Service &Amp; Participation During The Blood Donation Program At Ioi Mall Puchong On 15 Oct 2017, (15 Oct 2017 - 15 Oct 2017)
- Secretariat of Asian Orthopaedic Repair Society (Acrs), (07 Oct 2017 - 07 Oct 2019)
- Invited Speaker to Give a Presentation, Entitled "Cell Culture", During Inaugural Faculty of Medicine & Health Sciences (Fmhs) Scientific Meeting, Post-Conference Workshop, Meet The Experts Session: Sharing Experience On Bench Research, 2017-05-27 to 2017-05-27, Universiti Tunku Abdul Rahman, (National), (27 May 2017 - 27 May 2017)
- Invited Speaker to Give a Presentation, Entitled "Mesenchymal Stem Cells and Their Application in Articular Cartilage Regeneration: from Research to Clinical Application", Inaugural Faculty of Medicine & Health Sciences (Fmhs) Scientific Meeting, 2017-05-25 to 2017-05-26, Universiti Tunku Abdul Rahman, (International), (25 May 2017 - 26 May 2017)
- Member of Specialty Interest Group (Sig) Programme During Malaysia Orthopaedic Association (Moa) Meeting, (20 May 2017 - 20 May 2017)
- Event Organizer: Applications of Fluorescence & Confocal Imaging, Understanding Fluorescence Using Confocal Microscopy, 2017-05-18 to 2017-05-18, At National Orthopaedic Centre of Excellence in Research and Learning (Noceral), Department of Orthopaedic Surgery, Faculty of Medicine,University of Malay. Organizers: Malaysia Orthopaedic Association (Moa); Hi-Tech Instruments, (National), (18 May 2017 - 18 May 2017)
- I Have Provided The Mesenchymal Stem Cell Isolation & Culture to The Gmp Personnel from Cell and Tissue Transplantation Laboratory (Cttl), Ummc. it a Laboratory Which Follows Processing Based On Good Manufacturing Practice (Gmp), (07 Mar 2017 - 07 Mar 2017)
- Biotechnology Promotion to Secondary Schools in Malaysia, (22 Jun 2002 - 24 Jul 2005)