PERSONAL DETAIL


Prof. Dr. Onn Bin Haji Hashim

Professor
Department of Molecular Medicine
Faculty of Medicine
 
  79674906
  79674957
  onnhashim@um.edu.my
  Department of Molecular Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, MALAYSIA
 
ResearcherID Link
  http://www.researcherid.com/rid/B-9459-2010


BIBLIOMETRIC DATA


 Total Articles in Publication List  86
 Articles With Citation Data  83
 Sum of the Times Cited   648
 Average Citations per Article   7.81
 h-index   15
 Co-authors   Collaboration Network
 This information is generated from http://researcherid.com

BIOGRAPHY


Onn Haji Hashim received his BSc Hons degree from University of Malaya in September 1984, and PhD from University of Glasgow in December 1987.  He joined the academic staff of University of Malaya in January 1988, and is currently Professor grade VK5 at the Department of Molecular Medicine.  During the tenure, Onn has undertaken sabbatical leaves to conduct research at University of Osaka Medical School Japan in 1991, and University of Alabama at Birmingham USA in 1994, under sponsorships of JSPS Fellowship and American Fulbright Award, respectively.  He is recipient of the National Academic Award 2007 in the category of Publication of Journal Article, and was appointed Visiting Professor at Prince of Songkla University, Thailand, in 2016 and 2017.  Onn has acted as External Examiner of biochemistry programmes at nine medical and two dental schools, and External Examiner of PhD/MSc theses from six different universities, including those from Singapore and India.  He has supervised 12 PhD and 12 Master’s students to successful completion and delivered more than 50 guest lectures, locally and internationally.  His current research interest is in proteomics, particularly in the use of lectin-based techniques in search of novel glycopeptide biomarkers in serum, urine and saliva samples from patients with different cancers.  Onn is former Editor-in-Chief of Malaysian Journal of Biochemistry and Molecular Biology, and is presently member of the Editorial Board of Biomarker Research.  


ACADEMIC QUALIFICATION
(Qualification), (Institution).



PROFESSIONAL
(Organisation), (Role), (Year), (Level).


  • JUMMEC, Editorial Board Member, 2014-2016, (National)
  • Biomarker Research, Editorial Board Member, 2012, (International)
  • Malaysian Journal of Biochemistry and Molecular Biology, Editorial Board, 2006-2009, (National)
  • Malaysian Society for Biochemistry and Molecular Biology, Elected Council Member, 2003-2005, (National)

ADMINISTRATIVE DUTIES
(Role), (Level), (Start date),(End Date).


  • Health and Translational Medicine Research Cluster, Board of Advisor., University Malaya, 2010-01-01
  • Member (Alternate), Selection Committee of Post-Doctoral Research Fellow., University Malaya, 2008-01-02
  • Chairman of Ad-Hoc Committees to evaluate applications for PhD candidature., Faculty Of Medicine, 2008-01-01
  • Member, Panel for Renewal of Contract for Research Officer, University of Malaya., University Malaya, 2009-12-16
  • Head, Pusat Penyelidikan Proteomik, Advanced Fundamental Research, Research Cluster, Deputy Vice Chancellor(research & Innovation), 2016-01-01 - 2017-12-31
  • Head, Perubatan Molekul, Department Of Molecular Medicine, Faculty Of Medicine, 2014-08-01 - 2016-07-31
  • Head Of Department, Perubatan Molekul, Department Of Molecular Medicine, Faculty Of Medicine, 2014-08-01 - 2016-07-31
  • Head, Department of Molecular Medicine, University Malaya, 2014-08-01 - 2016-07-31
  • Member, University of Malaya Intellectual Property Evaluation Committee, University of Malaya Centre for Innovation and Commercialisation (UMCIC)., University Malaya, 2014-06-01 - 2016-06-30
  • Member, Advisory Committee of Centre for Research in Biotechnology for Agriculture (CEBAR)., University Malaya, 2014-05-01 - 2016-04-30
  • Head, Pusat Penyelidikan Proteomik, Advanced Fundamental Research, Research Cluster, Deputy Vice Chancellor(research & Innovation), 2015-01-01 - 2015-12-31
  • Head, University of Malaya Centre for Proteomics Research, University Malaya, 2015-01-01 - 2015-12-31
  • Head, Pusat Penyelidikan Proteomik, Advanced Fundamental Research, Research Cluster, Deputy Vice Chancellor(research & Innovation), 2014-01-02 - 2014-12-31
  • Head, University of Malaya Centre for Proteomics Research, University Malaya, 2014-01-01 - 2014-12-31
  • Panel member, Health and Translational Medicine Research Cluster., University Malaya, 2013-01-01 - 2014-12-31
  • Head Of Department, Perubatan Molekul, Department Of Molecular Medicine, Faculty Of Medicine, 2014-07-01 - 2014-07-31
  • Head, Department of Molecular Medicine, University Malaya, 2014-07-01 - 2014-07-31 (Head, Department of Molecular Medicine)
  • Head, Department of Molecular Medicine, University Malaya, 2012-09-01 - 2014-06-30
  • Head Of Department, Perubatan Molekul, Department Of Molecular Medicine, Faculty Of Medicine, 2012-09-01 - 2014-06-30
  • Head, University of Malaya Centre for Proteomics Research, University Malaya, 2012-01-01 - 2013-12-31
  • Panel member, Biotechnology and Bioproduct Research Cluster., University Malaya, 2011-01-01 - 2012-12-31
  • Panel member, Health and Translational Medicine Research Cluster., University Malaya, 2011-01-01 - 2012-12-31
  • Panel member, Advance Fundamental Research Cluster., University Malaya, 2011-01-01 - 2012-12-31 (Advance Fundamental Research Cluster, UM.)
  • Member, Faculty of Medicine Conference Committee., Faculty Of Medicine, 2009-10-11 - 2012-10-10
  • Head Of Department, Perubatan Molekul, Department Of Molecular Medicine, Faculty Of Medicine, 2012-07-01 - 2012-08-31
  • Head Of Department, Perubatan Molekul, Department Of Molecular Medicine, Faculty Of Medicine, 2011-07-09 - 2012-06-30
  • Head, Department of Molecular Medicine, University Malaya, 2011-07-09 - 2012-06-08
  • Biotechnology & Bioproduct Research Cluster, University of Malaya, Panel Member., University Malaya, 2009-01-01 - 2010-12-31
  • Member, Short-term Research Funding (PJP) Committee (Research University Special Grant)., University Malaya, 2008-01-01 - 2009-12-31
  • Member, Faculty of Medicine Conference Committee., Faculty Of Medicine, 2006-10-11 - 2009-10-10
  • Head Of Department, Department Of Molecular Medicine, Faculty Of Medicine, 2006-01-01 - 2009-08-31
  • Head Of Department, Perubatan Molekul, Department Of Molecular Medicine, Faculty Of Medicine, 2007-09-01 - 2009-08-31
  • Member, Faculty of Medicine Undergraduate Intake Committee., Faculty Of Medicine, 2006-01-01 - 2008-12-31
  • Proteomics Advisor, Medical Biotechnology Laboratory. , Faculty Of Medicine, 2006-01-01 - 2008-12-31
  • Head Of Department, Perubatan Molekul, Department Of Molecular Medicine, Faculty Of Medicine, 2006-09-01 - 2007-08-31
  • Head Of Department, Perubatan Molekul, Department Of Molecular Medicine, Faculty Of Medicine, 2006-06-01 - 2006-08-31
  • Head Of Department, Perubatan Molekul, Department Of Molecular Medicine, Faculty Of Medicine, 2006-04-01 - 2006-05-31
  • Head Of Department, Perubatan Molekul, Department Of Molecular Medicine, Faculty Of Medicine, 2006-01-01 - 2006-03-31
  • Phase I MBBS Course Coordinator., Faculty Of Medicine, 2004-01-01 - 2004-12-31
  • Medical Biochemistry Programme Coordinator for the MBBS course., Faculty Of Medicine, 2003-01-01 - 2003-12-31
  • Pharmaceutical Biochemistry Programme Coordinator for the BPharm course., Department Of Molecular Medicine, Faculty Of Medicine, 2000-01-01 - 2002-12-31

AREAS OF EXPERTISE
(Area).


  • Proteins (Human Serum Glycoproteins)
  • Plant Lectins (Plant Lectins)
  • Proteins (Cancer Biomarkers)
  • Proteins (Proteomics)
  • Proteins (Medical Biochemistry)


RECENT SELECTED PUBLICATIONS
(Publication).


Book

2003
  • Onn Hashim (2003) Metabolisme tubuh manusia (Human body metabolism) (2nd edition), UM Press, Kuala Lumpur, 327pp (ISBN 983-100-168-0). (Non-ISI/Non-SCOPUS)

2000
  • Onn Hashim (2000) Metabolisme tubuh manusia (Human body metabolism) (1st edition), UM Press, Kuala Lumpur, 275pp (ISBN 983-100-088-9). (Non-ISI/Non-SCOPUS)

Chapter In Book

1995
  • Mestecky, J., Hashim, O.H. and Tomana, M. (1995) Alterations in the IgA carbohydrate chains influence the cellular distribution of IgA1. In Clarkson AR, Woodroffe AJ (eds): IgA Nephropathy: Pathogenesis and Treatment. Karger Basel., Contribution to Nephrology, 111, 66-71 (ISBN 3-8055-6030-3; ISI-indexed). 

Article In Academic Journals

2016
  • Abdullah, M. I., Lee, C. C., Junit, S. M., Ng, K. L. and Hashim, O. H. (2016) Tissue and serum samples of patients with papillary thyroid cancer with and without benign background demonstrate different altered expression of proteins. PeerJ, 4, e2450. (ISI-Indexed)
  • Wan-Ibrahim WI, Ashrafzadeh A, Singh VA, Hashim OH, Abdul-Rahman PS (2016) Contrasting increased levels of serum amyloid A in patients with three different bone sarcomas: an indicator of tumour malignancy? Electrophoresis, in press; doi: 10.1002/elps.201500522. (ISI-Indexed)
  • Wong, S. Y., Lee, C. C., Ashrafzadeh, A., Junit, S. M., Abrahim, N. and Hashim, O. H. (2016) A high-yield two-hour protocol for extraction of human hair shaft proteins. PLoS ONE, 11(10): e0164993. (ISI-Indexed)
  • Phang WM, Tan AA, Gopinath SCB, Hashim OH, Kiew LV, Chen Y (2016) Secretion of N- and O-linked glycoproteins from 4T1 murine mammary carcinoma cells. Int J Med Sci, 13, 330-339. (ISI-Indexed)
  • Lee, C. C., Abdullah, M. I., Junit, S. M., Ng, K. L., Wong, S. Y., Ramli, N. S. F. and Hashim, O. H. (2016) Malignant transformation of benign thyroid nodule is caused by prolonged H2O2 insult that interfered with the STAT3 pathway? International Journal of Clinical and Experimental Medicine, 9(9), 18601-18617. (ISI-Indexed)
  • Subramanian P, Jayapalan JJ, Abdul-Rahman PS, Arumugam M, Hashim OH (2016) Temporal regulation of proteome profile in the fruit fly, Drosophila melanogaster. PeerJ, 4, e2080. (ISI-Indexed)
  • Lee, C. S., Taib, N. A. M., Ali, A., Fadzli, F., Harun, F., Rahmat, K., Hoong, S. M., Abdul-Rahman, P. S. and Hashim, O. H. (2016) Unmasking heavily O-glycosylated serum proteins using perchloric acid: identification of serum proteoglycan 4 and protease C1 inhibitor as molecular indicators for screening of breast cancer. PLoS ONE, 11(2): e0149551. (ISI-Indexed)
  • Mu AK, Lim BK, Aminudin N, Hashim OH, Shuib AS. 2016. Application of SELDI-TOF in N-glycopeptides Profiling of the Urine from Patients with Endometrial, Ovarian and Cervical Cancer. Archives of Physiology and Biochemistry 122(3): 111-116. (ISI-Indexed)

2015
  • Rahim, M. A. A., Rahim, Z. H. A., Ahmad, W. A. W. and Hashim, O. H. (2015) Can saliva proteins be used to predict the onset of acute myocardial infarction among high-risk patients? International Journal of Medical Sciences, 12, 329-335. (ISI-Indexed)
  • Tan, A.A., Phang, W.M., Gopinath, S.C.B., Hashim, O.H., Kiew, L.V. and Chen, Y. (2015) Revealing glycoproteins in the secretome of MCF-7 human breast cancer cells. BioMed Research International, 2015, 453289. (ISI-Indexed)
  • Subramanian, P. Anandan, R., Jayapalan, J.J. and Hashim, O.H., (2015) Hesperidin protects gentamicin- induced nephrotoxicity via Nrf2/HO-1 signaling and inhibits inflammation mediated by NF-κB in rats. Journal of Functional Foods, 13, 89-99. (ISI-Indexed)
  • Subramanian, P. Jayakumar, M., Singaravel, M., Kumar, D., Basu, P., Jayapalan, J.J. and Hashim, O.H., (2015) Fisetin, a dietary flavonoid, attenuates hyperammonemia and improves circadian locomotor deficits, redox balance, and astrocytic markers in rats. Journal of Functional Foods, 12, 409-419. (ISI-Indexed)
  • Wan-Ibrahim Wan Izlina, Singh Vivek Ajit, Hashim Onn Haji and Abdul-Rahman Puteri Shafinaz. (2015). Biomarkers for Bone Tumours: Discovery from Genomics and Proteomics Studies and Their Challenges. MOL MED 21:861-872 (ISI-Indexed)

2014
  • Subramanian, P. Jayakumar, M., Jayapalan, J.J. and Hashim, O.H., (2014) Chronotherapeutic effect of fisetin on expression of urea cycle enzymes and inflammatory markers in hyperammonaemic rats. Pharmacological Reports, 66, 1037-1042. (ISI-Indexed)
  • Nga, A.D.C., Yap, S.L., Samsudin, A., Abdul-Rahman, P.S., Hashim, O.H. and Mimiwati, Z. (2014) Matrix metalloproteinases and tissue inhibitors of metalloproteinases in the aqueous humour of patients with primary angle closure glaucoma - a quantitative study. BMC Ophthalmology, 14, 33. (ISI-Indexed)
  • Subramanian, P., Jayapalan, J.J. and Hashim, O.H. (2014) Chronotherapy: a noteworthy focal point in the treatment of cancer?. Biological Rhythm Research, accepted/in press. (ISI-Indexed)
  • Verma, D., Hashim, O. H., Jayapalan, J. J. and Subramanian, P. (2014) Effect of melatonin on antioxidant status and circadian activity rhythm during hepatocarcinogenesis. Journal of Cancer Research and Therapeutics, 10, 1040-1044. (ISI-Indexed)
  • Jayakumar, M., Hashim, O.H. and Subramanian, P. (2014) Anti-hyperammonaemic effect of fisetin in rats: a chronotherapeutic study. International Journal of Phytomedicine, 6, 73-81. (SCOPUS-Indexed)
  • Subramanian, P., Prasanna, V., Jayapalan, J.J. and Abdul- Rahman, P.S., Hashim, O.H., (2014) Role of Bacopa monnieri in the temporal regulation of oxidative stress in clock mutant (cryb) of Drosophila melanogaster. Journal of Insect Physiology, 65, 37-44. (ISI-Indexed)
  • Al-Obaidi, J.R., Mohd-Yusuf, Y., Razali, N., Jayapalan, J., Tey, C.-C., Normahnani Md-Noh, N., Junit, S.M., Othman, R.Y. and Hashim, O.H. (2014) Identification of proteins of altered abundance in oil palm infected with Ganoderma boninense. International Journal of Molecular Sciences, 15, 5175-5192. (ISI-Indexed)
  • Gabrielsen, M., Abdul-Rahman, P.S., Othman, S., Hashim, O.H. and Cogdel, R.J. (2014) Structures and binding specificity of galactose- and mannose-binding lectins from champedak: differences with jackfruit lectins. Acta Crystallographica Section F, 70, 709-716. (ISI-Indexed)
  • Nga ADC, Yap SL, Samsudin A, Abdul-Rahman PS, Hashim OH, Mimiwati Z. Matrix metalloproteinases and tissue inhibitors of metalloproteinases in the aqueous humour of patients with primary angle closure glaucoma - a quantitative study. BMC Ophthalmology 2014;14:33 (ISI/SCOPUS Indexed Publication)
  • Jessie, K., Jayapalan, J. J., Rahim, Z. H. A., and Hashim, O. H. (2014) Aberrant proteins featured in the saliva of habitual betel quid chewers: an indication of early oral premalignancy? Electrophoresis, 35, 3504-3511. (ISI-Indexed)

2013
  • Abdelwahab, S.I., Taha, M. M. E, Abdulla, M. A., Nordin, N., Hadi, A. H. A., Mohan, S., Jayapalan, J. J. and Hashim, O. H. (2013) Gastroprotective mechanism of Bauhinia thonningii Schum. Journal of Ethnopharmacology, 148, 277-286. (ISI-Indexed)
  • Jayapalan, J. J., Ng, K. L., Shuib, A. S., Razack, A. H. A. and Hashim, O. H. (2013) Urine of patients with early prostate cancer contains lower levels of light chain fragments of inter-alpha-trypsin inhibitor and saposin B but increased expression of an inter-alpha-trypsin inhibitor heavy chain 4 fragment. Electrophoresis, 34, 1663-1669. (ISI-Indexed)
  • Mohamed, E., Jayapalan, J. J., Abdul-Rahman, P. S., Omar, S. Z. and Hashim, O. H. (2013) Enhanced expression of a 35 kDa fragment of inter- alpha- trypsin inhibitor H4 in sera of healthy pregnant women and patients with hydatidiform mole. Biomarker Research, 1:19. (Non-ISI/Non-SCOPUS)
  • Chong, U. R. W., Abdul-Rahman, P. S., Abdul-Aziz, A., Hashim, O. H. and Mat-Junit, S. (2013) Effects of Tamarindus indica fruit pulp extract on abundance of HepG2 cell lysate proteins and their possible consequential impact on metabolism and inflammation. BioMed Research International, 2013, 459017. (ISI-Indexed)
  • Lee, C.S., Muthusamy, A., Abdul-Rahman, P. S., Bhavananthan, V. and Hashim, O. H. (2013) An improved lectin-based method for the detection of mucin-type O-glycans in biological samples. Analyst, 138, 3522-3529. (ISI/SCOPUS Indexed Publication)
  • Mariappan, V., Vellasamy, K.M., Thimma, J., Hashim, O.H. and Vadivelu, J. (2013) Infection of Burkholderia cepacia induces homeostatic responses in the host for their prolonged survival: the microarray perspective. PLoS ONE, 8(10): e77418. (ISI-Indexed)
  • Mu A.K., Lim B.K., Hashim O.H., Shuib A.S. 2013. Identification of o-glycosylated proteins that are aberrantly excreted in the urine of patients with early stage ovarian cancer. International Journal of Molecular Sciences. 14(4):7923-7931. (ISI-Indexed)
  • Jessie, K., Jayapalan, J. J., Ong, K. C., Rahim, Z. H. A., Zain, R. M., Wong, K. T. and Hashim, O. H. (2013) Aberrant proteins in the saliva of patients with oral squamous cell carcinoma. Electrophoresis, 34, 2495- 2502. (ISI-Indexed)

2012
  • Vellasamy, K.M., Mariappan, V., Hashim, O.H. and Vadivelu, J. (2012) Functions of Burkholderia virulence factors: Input from proteomics and DNA microarray analyses. Journal of Analytical Science and Technology, 3:72-80. 
  • Chan, H. H., Rahim, Z.H.A., Jessie, K., Hashim, O.H. and Taiyeb-ali T. B. (2012) Salivary proteins associated with periodontitis in patients with Type 2 diabetes mellitus. International Journal of Molecular Sciences, 13, 4642-4654. (ISI-Indexed)
  • Jayapalan, J. J., Ng, K. L., Razack, A. H. A. and Hashim, O. H. (2012) Identification of potential complementary serum biomarkers to differentiate prostate cancer from benign prostatic hyperplasia using gel- and lectin-based proteomics analyses. Electrophoresis, 33, 1855-1862. (ISI-Indexed)
  • Aminudin N, Abdullah NAH, Misbah H, Karsani SA, Husain R, Hoe SZ and Hashim OH. 2012. Treatment with captopril abrogates the altered expression of alpha1 macroglobulin and alpha1 antiproteinase in sera of spontaneously hypertensive rats. Proteome Science. 2012, 10:17 doi:10.1186/1477-5956-10-17 (ISI/SCOPUS Indexed Publication)
  • Chong URW, Abdul-Rahman PS, Abdul-Aziz A, Hashim OH, Mat-Junit S. (2012) Tamarindus indica Extract Alters Release of Alpha Enolase, Apolipoprotein A-I, Transthyretin and Rab GDP Dissociation Inhibitor Beta from HepG2 Cells. PLOS ONE, 7(6): e39476. (ISI-Indexed)
  • Alan Kang-Wai Mu, Lim B.K., Hashim O.H. Shuib A.S. 2012. Detection of differential levels of proteins in the urine of patients with endometrial cancer: analysis using two-dimensional gel electrophoresis and O-glycan binding lectin. International Journal of Molecular Sciences 13: 9489-9501 (ISI-Indexed)

2011
  • Mariappan, V., Vellasamy, K.M., Hashim, O.H. and Vadivelu, J. (2011) Profiling of Burkholderia cepacia secretome at mid-logarithmic and early-stationary phases of growth. PLoS ONE 6(10): e26518. doi:10.1371/journal.pone.0026518. (ISI-Indexed)
  • Golbabapour, S., Pang, W.W., George, J., Pasupati, T., Abdul-Rahman, P.S. and Hashim, O.H. (2011) Chemically induced breast tumors in rats are detectable in early stages by contrast enhanced magnetic resonance imaging but not by changes in the acute-phase reactants in serum. International Journal of Molecular Sciences, 12, 1030-1040. (ISI-Indexed)
  • Vellasamy, K.M., Mariappan, V., Hashim, O.H. and Vadivelu, J. (2011) Identification of immunoreactive secretory proteins from the stationary phase culture of Burkholderia pseudomallei. Electrophoresis, 32, 310- 320. (ISI-Indexed)
  • Manap, M. N. A, Hashim, O. H. and Mohd. Yusoff, K. (2011) Malaysian bee venom abrogates carrageenan induced inflammation in rats. Journal of Apiproduct and Apimedical Science, 3, 75-80. 

2010
  • Pang, W.W., Abdul-Rahman, P.S., Wan-Ibrahim, W.I. and Hashim, O.H. (2010) Can the acute-phase reactant proteins be used as cancer biomarkers? International Journal of Biological Markers, 25, 1-11. (ISI-Indexed)
  • Mariappan, V., Vellasamy, K.M., Thimma, J.S., Hashim, O.H. and Vadivelu, J. (2010) Identification of immunogenic proteins from Burkholderia cepacia secretome using proteomic analysis. Vaccine, 28, 1318- 1324. (ISI-Indexed)
  • Gabrielsen, M., Abdul-Rahman, P.S., Isaacs, N.W., Hashim, O.H. and Cogdell, R.J. (2010) Crystallization and initial X-ray diffraction analysis of a mannose- binding lectin from Champedak. Acta Crystallographica F, 66, 592-594. (ISI-Indexed)
  • Seriramalu, R., Pang, W. W., Jayapalan, J. J., Mohamed, E., Abdul-Rahman, P. S., Bustam, A. Z., Khoo, A. S. B. and Hashim, O. H. (2010) Application of champedak mannose binding lectin in the glycoproteomic profiling of serum samples unmasks reduced expression of alpha-2 macroglobulin and complement factor B in patients with nasopharyngeal carcinoma. Electrophoresis, 31, 2388-2395. (ISI-Indexed)
  • Jessie, K., Pang, W.W., Rahim, Z.H.A. and Hashim, O.H. (2010) Proteomic analysis of whole human saliva detects enhanced expression of interleukin-1 receptor antagonist, thioredoxin and lipocalin-1 in cigarette smokers compared to non-smokers, International Journal of Molecular Sciences, 11, 4488-4505. (ISI-Indexed)
  • Abdullah-Soheimi, S.S., Lim, B.K., Hashim, O.H. and Shuib, A.S. (2010) Patients with ovarian carcinoma excrete different altered levels of urine CD59, kininogen-1 and fragments of inter-alpha-trypsin inhibitor heavy chain H4 and albumin. Proteome Science, 8:58 (doi:10.1186/1477-5956-8-58). (ISI-Indexed)

2009
  • Chen, Y., Lim, B.K. and Hashim, O.H. (2009) Stage correlative expression of high abundance acute-phase proteins in sera of patients with epithelial ovarian carcinoma. Journal of Hematology and Oncology, 2, 37 (doi:10.1186/1756-8722-2-37) (ISI-Indexed)
  • Gabrielsen, M., Riboldi-Tunicliffe, A., Abdul-Rahman, P.S., Mohamed, E., Ibrahim, W.I.W., Hashim, O.H., Isaacs, N.W. and Cogdell, R.J. (2009) Crystallization and preliminary structural studies of Champedak galactose-binding lectin, Acta Crystallographica F, 65, 895-897. (ISI-Indexed)

2008
  • Chen, Y., Lim, B.K., Peh, S.C., Abdul-Rahman, P.S. and Hashim, O.H. (2008) Profiling of serum and tissue high abundance acute-phase proteins of patients with epithelial and germ line ovarian carcinoma. Proteome Science, 6, 20. (ISI-Indexed)
  • Jessie, K., Hashim, O.H. and Rahim, Z.H.A. (2008) Precipitation methods for salivary proteins and rehydration buffer for two-dimensional electrophoresis, Biotechnology, 7(4), 686-693. 
  • Mohamed, E., Abdul-Rahman, P.S., Doustjalali, S.R., Chen, Y., Lim, B.K., Omar, S.Z., Bustam, A.Z., Singh, V.A., Muhammad-Taib, N.A., Yip, C.H. and Hashim, O.H. (2008) Lectin-based electrophoretic analysis of the expression of the 35 kDa inter-alpha-trypsin inhibitor heavy chain H4 fragment in sera of patients with five different malignancies. Electrophoresis, 29, 2645- 2650. (ISI-Indexed)

2007
  • Abdul-Rahman, P.S., Lim, B.K. and Hashim, O.H. (2007) Expression of high abundance proteins in sera of patients with endometrial and cervical cancers: analysis using two-dimensional gel electrophoresis with silver staining and lectin detection methods, Electrophoresis, 28, 1989-1996. (ISI-Indexed)
  • Hashim, O. H. (2007) Overview of proteomics (a review), Malaysian Journal of Biochemistry and Molecular Biology, 15, 1-7. (Non-ISI/Non-SCOPUS)

2006
  • Muliawan S.Y., Lam, S.K., Devi, S., Hashim, O.H. and Yusof, R. (2006) Inhibitory potential of Quercus lusitanica extract on dengue virus type 2 replication, Southeast Asian Journal of Tropical Medicine and Public Health, 37, 132-135. (SCOPUS-Indexed)
  • Yong, P.H., Mat Junit, S., Harun, F. and Hashim, O.H. (2006) Patients with congenital hypothyroidism demonstrate different altered expression of plasma fibrinogen and haptoglobin polypeptide chains, Clinical Biochemistry, 39, 126-132. (ISI-Indexed)
  • Doustjalali, S.R., Yusof, R., Govindasamy, G.K., Bustam, A.Z., Pillay, B. and Hashim, O.H. (2006) Patients with nasopharyngeal carcinoma demonstrate enhanced serum and tissue ceruloplasmin expression, Journal of Medical Investigation, 53, 20-28. (ISI/SCOPUS Indexed Publication)

2004
  • Doustjalali, S.R., Yusof, R., Yip, C.H., Looi, L.M., Pillay B. and Hashim, O.H. (2004) Aberrant expression of acute-phase reactant proteins in sera and breast lesions from patients with malignant and benign breast tumours, Electrophoresis, 25, 2392-2401. (ISI-Indexed)

2002
  • Abdul Rahman, M., Karsani, S.A., Othman, I., Abdul Rahman, P.S. and Hashim, O.H. (2002) Galactose binding lectin from the seeds of champedak (Artocarpus integer): sequences of its subunits and interactions with human serum O-glycosylated glycoproteins, Biochemical and Biophysical Research Communications. 295, 1007-1013. (ISI-Indexed)

2001
  • Hashim, O.H., Ahmad, F. and Shuib, A.S. (2001) The application of Artocarpus integer seed lectin-M in the detection and isolation of selective serum acute-phase proteins and immunoglobulins, Immunological Investigations, 30, 131-141. (ISI-Indexed)
  • Hashim, O.H., Shuib, A.S. and Chua, C.T. (2001) Neuraminidase treatment abrogates the binding abnormality of IgA1 from IgA nephropathy patients and the differential charge distribution of its alpha-heavy chains, Nephron, 89, 422-425. (ISI-Indexed)
  • Hashim, O.H., Shuib, A.S. and Chua, C.T. (2001) The interaction of selective plant lectins with neuraminidase-treated and untreated IgA1 from the sera of IgA nephropathy patients, Immunological Investigations, 30, 21-31. (ISI-Indexed)
  • Hashim, O.H. and Shuib, A.S. (2001) Champedak and jackfruit galactose-reactive lectins demonstrated minor preferential binding to electrophoresed alpha-heavy chains lacking in sialic acid residues, Malaysian Journal for Biochemistry and Molecular Biology, 6, 40-43. (Non-ISI/Non-SCOPUS)
  • Hashim, O.H. and Shuib, A.S. (2001). Champedak and jackfruit galactose-reactive lectins demonstrated minor preferential binding to electrophoresed alpha-heavy chains lacking in sialic acid residues. Mal. J. Biochem. Mol. Biol. 6. 40-43. 

1998
  • Lim, S.B., Kanthimathi, M.S. and Hashim, O.H. (1998) Effect of the mannose-binding Artocarpus integer lectin on the cellular proliferaton of murine lymphocytes. Immunological Investigations, 27, 395-404. (ISI-Indexed)
  • Shuib, A.S., Chua, C.T. and Hashim, O.H. (1998) Sera of IgA nephropathy patients contain a heterogeneous population of relatively cationic alpha heavy chains. Nephron, 78, 290-295. (ISI-Indexed)

1997
  • Lim, S.B., Chua, C.T. and Hashim, O.H. (1997) Isolation of a mannose-binding and IgE- and IgM-reactive lectin from the seeds of Artocarpus integer. Journal of Immunological Methods, 209, 177-186. (ISI-Indexed)

1994
  • Hashim, O.H., Gendeh, G.S., Cheong, C.N. and Nik Jaafar, M.I. (1994) Effect of Artocarpus integer lectin on functional activity of guinea-pig complement. Immunological Investigations, 23, 153-160. (ISI-Indexed)
  • Hashim, O.H. and Adnan, N.A. (1994) Coenzyme, cofactor and prosthetic group - ambiguous biochemical jargon. Biochemical Education, 22, 93-94. (ISI-Indexed)

1993
  • Hashim, O.H., Gendeh, G.S. and Nik Jaafar, M.I. (1993) Comparative analyses of IgA1 binding lectins from seeds of six distinct clones of Artocarpus integer. Biochemistry and Molecular Biology International, 29, 69-76. (ISI-Indexed)

1992
  • Hashim, O.H., Gendeh, G.S. and Nik Jaafar, M.I. (1992) Lectin extracts of champedak seeds demonstrate selective stimulation of T lymphocyte proliferation. Biochemistry International, 27, 139-143. (ISI-Indexed)
  • Hashim, O.H., Kobayashi, K. and Taniguchi, N. (1992) Interaction of Artocarpus lectins with human IgA does not involve asparagine-linked oligosaccharide of the immunoglobulin. Biochemistry International, 27, 423-429. (ISI-Indexed)

1991
  • Hashim, O.H., Ng, C.L., Gendeh, G.S. and Nik Jaafar, M.I. (1991) IgA binding lectins from distinct Artocarpus species demonstrate differential specificity. Molecular Immunology, 28, 393-398. (ISI-Indexed)
  • Hashim, O.H. (1991) The ELISA test (a video review). Biochemical Education, 19, 38. (ISI-Indexed)
  • Hashim, O.H. and Hassan, H. (1991) Actions of three Clostridial IgA proteases on distinct forms of immunoglobulin A molecules. Immunology, 73, 235-238. (ISI-Indexed)

1988
  • Hashim, O.H. and Cushley, W. (1988) Simultaneous inhibition of multiple steps in the processing of N-linked oligosaccharides does not impair immunoglobulin secretion from rat hybridoma cells. Immunology, 63, 383-388. (ISI-Indexed)

1987
  • Hashim, O.H. and Cushley, W. (1987) Minor modifications to the structure of Tunicamycin lead to loss of the biological activity of the antibiotic. Biochimica et Biophysica Acta, 923, 362-370. (ISI-Indexed)
  • Hashim, O.H. and Cushley, W. (1987) Role of processing of N-linked oligosaccharides in control of immunoglobulin secretion from rat hybridomas. Molecular Immunology, 24, 1087-1096. (ISI-Indexed)

Proceeding

2010
  • Hashim, O.H. (2010) Cancer biomarkers from the proteome. 35th Ann. Conf. Mal. Soc. Biochem. Mol. Biol. Conf., Bangi, p23. 
  • Mu, A.K.W., Lim, B.K., Hashim, O.H. and Shuib, A.S. (2010) Glycoproteomic analysis of aberrantly glycosylated urinary proteins from endometrial cancer by lectin blotting. 35th Ann. Conf. Mal. Soc. Biochem. Mol. Biol. Conf., Bangi, p49. 
  • Doustjalali, S. R., Chen, Y., Abdul-Rahman, P. S., Mohamed, E., Seriramalu, R., Pang, W. W. and Hashim, O. H. (2010) Gel- and lectin-based serum proteomics profiling in search for new complementary biomarkers for cancer. National Biotechnology Conference, PWTC. 

2009
  • Hashim, O.H. (2009) Acute-phase protein response: can it be used as a diagnostic tool for cancer? PepCon2009, Seoul, p135. 
  • Mohamed, E., Abdul-Rahman, P.S., Omar,S.Z. and Hashim, O.H. (2009) Association of sex steroid hormone dysregulation with the over expression of serum 35 kDa inter alpha trypsin H4 fragment. 21st IUBMB and 12th FAOBMB International Congress of Biochemistry and Molecular Biology, Shanghai. p217 
  • Wan-Ibrahim, W.I., Karsani, S.N., Hashim, O.H. and Abdul-Rahman, P.S. (2009) Establisment of serum O- glycoproteome using shot-gun-MS analysis. 34th Annual Conference of the Malaysian Society for Biochemistry and Molecular Biology, and 3rd ASEAN Biochemistry Conference. 7-8 October 2009 Kuala Lumpur. p33 
  • Vanitha, M., Kumutha, M.V., Thimma, J., Hashim, O.H. and Vadivelu J. (2009) Comparison of immunogenic proteins by immunoproteome analysis of Burkholderia cepacia secretome. 10th APRU Doctoral Students Conference, Kyoto. 
  • Vanitha, M., Kumutha, M.V., Thimma J., Hashim, O.H. and Vadivelu, J. (2009) Immunoproteomic analysis of Burkholderia cepacia secretory proteins at different growth phase. The 14th Biological Sciences Graduate Congress. Chulalangkorn. 
  • Kumutha, M.V., Vanitha, M., Hashim, O.H. and Vadivelu, J.(2009) Proteome mapping and identification of Burkholderia pseudomallei secreted proteins. 14th Biological Sciences Graduate Congress. Chulalangkorn. 
  • Nga, D.C., Abdul-Rahman, P.S., Hashim, O.H. and Mimiwati, Z. (2009) Matrix Metalloproteinases and their inhibitor in aqueous humour of patients with open-angle glaucoma and primary angle-closure glaucoma. World Glaucoma Congress, Boston, p96. 
  • Abdul-Rahman, P.S., Mohamed, E., Singh, V.A. and Hashim, O.H. (2009) Patients with different bone cancers demonstrate distinctive altered expression of serum protein profiles. EMBO Cancer Proteomics, Dublin, p1. 

2008
  • Abdul-Rahman, P.S., Lim, B.K., Yunos, N.M., Adnan, M.I. and Hashim, O.H. (2008) SELDI-MS Profiling of O-glycosylated proteins in sera of patients with endometrial adenocarcinoma. FEBS Journal 275, 242. (ISI-Indexed)
  • Mohamed, E., Shanaz, A.R.P., Omar, S.Z., Abdul-Rahman, P.S. and Hashim, O.H. (2008) Lectin-generated serum O-glycosylated proteins in sera of patients with hydatidiform mole. FEBS Journal 275, 246. (ISI-Indexed)
  • Abd-Manap, M.N., Hashim, O.H., Zubairi Y.Z. and Yusoff, K.M. (2008) Anti-inflammatory effect of Malaysian bee venom. VI German Apitherapy and Acupuncture Congress, Passau. 
  • Abd-Manap, M.N., Hashim, O.H., Mohamed, E., Abdul-Rahman, P.S. and Yusoff, K.M. (2008) Discovery of bee venom bioactive components: a proteomic approach. VI German Apitherapy and Acupuncture Congress, Passau. 
  • Abd-Manap, M.N., Hashim, O.H., Mohamed, E., Abdul-Rahman, P.S. and Yusoff, K.M. (2008) Proteomic analysis of differentially expressed proteins in sera of carrageenan induced rats treated with Malaysian bee venom. VI German Apitherapy and Acupuncture Congress, Passau. 
  • Kumutha M.V. , Vanitha M., Thimma J., Hashim O. and Vadivelu J. (2008) Immunoproteomics analysis of Burkholderia pseudomallei secretome. 13th Biological Sciences Graduate Congress (BSGC), Singapore, p26. 
  • Vanitha, M. , Kumutha, M.V. , Thimma, J., Hashim O. and Vadivelu J. (2008) Comparison of immunogenic proteins by immunoproteome analysis of Burkholderia cepacia secretome. 13th Biological Sciences Graduate Congress (BSGC), Singapore, p28. 
  • Mohamed, E., Abdul-Rahman, P.S., Omar, S.Z. and Hashim, O.H. (2008) Overexpression of the 35kDa ITIH4 fragment: Exclusive to sex-steroid hormone associated cancer. Mal. J. Biochem. Mol. Biol. 17(1), 33. 
  • Seriramalu, R., Abdul-Rahman, P.S., Bustam, A.Z., Khoo, A. and Hashim, O.H. (2008) Two-dimensional gel electrophoretic profiling of low abundance serum proteins of patients with nasopharyngeal carcinoma WHO types 2 and 3. Mal. J. Biochem. Mol. Biol., 17 (1), 52. 
  • Soheimi, S.S., Lim, B.K., Omar, S.Z., Hashim, O.H. and Shuib, A.S. (2008) Two-dimensional gel electrophoretic analysis of urinary proteins of patients with ovarian carcinoma and cervical cancer. Mal. J. Biochem. Mol. Biol., 17(1), 99. 
  • Vanitha, M. , Kumutha, M.V. , Hashim O. and Vadivelu J. (2008) Identification of immunoreactive secretory antigens from Burkholderia cepacia against monoclonal antibody. International Journal of Infectious Diseases, 12: 227. (ISI-Indexed)
  • Kumutha M.V. , Vanitha M., Thimma J., Hashim O. and Vadivelu J. (2008) Invasion efficiency of Burkholderia pseudomallei from different clinical sources. International Journal of Infectious Diseases, 12: 228. (ISI-Indexed)
  • Abdul-Rahman, P.S., Yunos, N.M., Adnan, M.I., Lim, B.K. and Hashim, O.H. (2008) Profiling of O-glycosylated proteins in sera of patients with endometrial adenocarcinoma. Mal.J. Biochem. Mol. Biol., 16, 70. 
  • Kang, I.N., Musa, M., Yong, P.H., Mansor, S.F., Harun, F., Hashim, O.H. and Junit, S.M. (2008) Novel mutations and polymorphisms in thyroid-specific genes in patients with congenital hypothyroidism. Mal.J. Biochem. Mol. Biol., 16, 69. 
  • Rosli, S.N.Z., Hashim, O.H., Mohd-Zain, R., Hussaini, H.M., Abdul-Rahman, M., Zainal-Abidin, Z., and Karsani, S.A. (2008) Identification of differentially expressed proteins in the serum of oral cancer patients by two-dimensional electrophoresis. Mal.J. Biochem. Mol. Biol., 16, 67. 
  • Mohamed, E., Abdul-Rahman, P., Omar, S.Z. and Hashim, O.H. (2008) Serum two-dimensional electrophoretic profiles of patients with molar pregnancy. Mal.J. Biochem. Mol. Biol., 16, 62. 
  • Shuib, A.S., Murat, S.S.C., Sulaiman, S and Hashim, O.H. (2008) Development of CGB-lectin-based latex agglutination assay in detecting hCG. Mal.J. Biochem. Mol. Biol., 16, 51. 
  • Abdul-Manap, M.N., Mohd. Yusoff, K., Hashim, O.H. and Zubairi, Y.Z. (2008) Malaysian bee venom abrogates carrageenan-induced inflammatory effects in rats. Mal.J. Biochem. Mol. Biol., 16, 45. 
  • Che Murat, S.S., Hashim, O.H., Sulaiman, S. and Shuib, A.S. (2008) Interaction of the champedak galactose binding lectin with O-linked oligosaccharides of human chorionic gonadotropin. Mal. J. Biochem. Mol. Biol., 17 (1), 68. 

2007
  • Hashim, O.H. (2007) Proteomics and cancer. J. Health Management., p27. 
  • Rosli, S.N.Z., Hashim, O.H., Mohd-Zain, R, Mohd-Hussaini, H., Abdul-Rahman, M., Zainal-Abidin, Z. and Karsani, S.A. (2007) Identification of differentially expressed proteins in serum samples of oral cancer patients by two dimensional electrophoresis. 2nd Reg. Conf. Mol. Med., Kuala Lumpur, p52. 
  • Abdul-Rahman, P.S., Yunos, N.M., Adnan, M.I., Lim, B.K. and Hashim, O.H. (2007) Profiling of O-glycosylated proteins in sera of patients with endometrial adenocarcinoma using SELDI-MS. 32nd Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Petaling Jaya, p122. 
  • Kang, I.N., Musa, M., Yong, P.H., Mansor, S.F., Harun, F., Hashim, O.H. and Junit, S.M. (2007) Novel mutations and polymorphisms in thyroid-specific genes in patients with congenital hypothyroidism. 32nd Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Petaling Jaya, p119. 
  • Rosli, S.N.Z., Hashim, O.H., Mohd-Zain, R., Hussaini, H.M., Abdul-Rahman, M., Zainal-Abidin, Z., and Karsani, S.A. (2007) Identification of differentially expressed proteins in the serum of oral cancer patients by two-dimensional electrophoresis. 32nd Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Petaling Jaya, p113. 
  • Mohamed, E., Abdul-Rahman, P., Omar, S.Z. and Hashim, O.H. (2007) Serum two-dimensional electrophoretic profiles of patients with molar pregnancy. 32nd Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Petaling Jaya, p101. 
  • Shuib, A.S., Murat, S.S.C., Sulaiman, S and Hashim, O.H. (2007) Development of CGB-lectin-based latex agglutination assay in detecting hCG, 32nd Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Petaling Jaya, p67. 
  • Abdul-Manap, M.N., Mohd. Yusoff, K., Hashim, O.H. and Zubairi, Y.Z. (2007) Malaysian bee venom abrogates carrageenan-induced inflammatory effects in rats. 32nd Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Petaling Jaya, p48. 
  • Mariappan, V., Vellasamy, K.M., Suppiah, J., Thimma, J., Hashim, O.H. and Vadivelu, J. (2007) Identification of common immunodominant secretory antigens between Burkholderia cepacia and Burkholderia pseudomallei. 5th World Melioidosis Congress, Khon Kean, gep008. 
  • Abdul-Rahman P.S., Chen, Y, Doustjalali, S.R., Mohamed, E., Lim, B.K., Mohd-Taib, N.A., Yip, C.H. and Hashim, O.H. (2007) Profiling of O-glycosylated serum proteins of patients with cancer using the gel-based proteomics approach and lectin detection. Int. Symp. Glycoconjugate, Cairns, Glycoconj. J. 24, 334. (ISI-Indexed)

2006
  • Abdul Rahman, P.S., Lim, B.K. and Hashim, O.H. (2006) Serum proteomic profiling of patients with endometrial and cervical carcinomas. 31st Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Bangi, p57. 
  • Abdul Rahman, P.S., Lee, E.S., Hashim, O.H. and Shuib, A.S. (2006) Application of lectin-coated magnetic beads in the proteomic profiling of human serum glycoprotein. 31st Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Bangi, p58. 
  • Vellasamy, K.M., Mariappan, V., Vadivelu, J., and Hashim, O.H. (2006) Comparison of secretory protein profile of Burkholderia pseudomallei and Burkholderia thailandensis using two-dimensional gel electrophoresis. 16th Sci. Meet. Mal. Soc. Mol. Biol Biotech., Kuala Lumpur. 
  • Mariappan, V., Vellasamy, K.M., Vadivelu, J., and Hashim, O.H. (2006) Comparative proteome analysis of extracellular secreted protein from Burkholderia cepacia at different growth phase. 16th Sci. Meet. Mal. Soc. Mol. Biol Biotech., Kuala Lumpur. 

2005
  • Hashim, O.H. and Shuib, A.S. (2005) Lectin-based urinary hCG detection for confirmation of pregnancy. 3rd Nat. Biotech. Conf., New Delhi, p75. 
  • Hashim, O.H. (2005) Proteomics approach to cancer studies. 2nd Int. UM Res. Imaging Symp., Subang Jaya, p12. 
  • Shuib, A.S., Hashim, O.H., Sulaiman, S and Omar, S.Z. (2005) Urinary proteomics of molar disease, 15th Sci. Meet. Mal. Soc. Mol. Biol. Biotech., Kuala Lumpur, p17. 
  • Abdul Rahman, P.S., Lim, B.K., Mian, S., Rees, R. and Hashim, O.H. (2005) Application of lectin affinity chromatography and mass spectrometry for profiling of human serum glycoproteins. 15th Sci. Meet. Mal. Soc. Mol. Biol. Biotech., Kuala Lumpur, p17. 

2004
  • Doustjalali, S.R., Yusof, R., Govindasamy, G.K., Bustam, A.Z., Pillay, B. and Hashim, O.H. (2004) Potential role of caeruloplasmin as a novel biomarker for diagnosis and monitoring of nasopharyngeal carcinoma, Fed. Asian Oceanian Biochem. Mol. Biol. Meet., Bangkok, p68. 
  • Abdullah, A., Lim, B.K., Hashim, O.H. and Yusof, R. (2004) HPV detection and biomarkers screening to monitor cervical cancer persistency, 14th Sci. Meet. Mal. Soc. Mol. Biol. Biotech., Malacca, p44. 
  • Chai, H.C., Tay, S.T., and Hashim, O.H. (2004) A preliminary study on the proteome of Cryptococcus neoformans and identification of immunogenic proteins, 14th Sci. Meet. Mal. Soc. Mol. Biol. Biotech., Malacca, p50. 
  • Chen, Y., Lim, B.K., and Hashim, O.H. (2004) Serum protein profiles of ovarian carcinoma patients, 14th Sci. Meet. Mal. Soc. Mol. Biol. Biotech., Malacca, p53. 
  • Hashim, O.H. (2004) Lectins from the seeds of champedak; from waste to wonders, 29th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Kuala Lumpur, p18-19. 
  • Chen, Y., Lim, B.K., and Hashim, O.H. (2004) Two dimensional serum protein profiles of patients with germ cell and epithelial ovarian carcinomas, 29th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Kuala Lumpur, p128. 
  • Kanthimathi, M.S., Chai, J.W., Lee, I.L., Kuppusamy, U.R., Wiart, C. and Hashim, O.H. (2004) Protein expression in cancer cells treated with selected plant extracts, 11th Ann. Meet Soc. for Free Radicals and Radioprotectors, India, p71. 

2003
  • Doustjalali, S.R., Yusof, R., Othman, I., Yip, C.H., Looi, L.M. and Hashim, O.H. (2003) Patients with breast disorders demonstrate aberrant two-dimensional electrophoretic serum protein expression maps, Int. Council Electro. Soc Conf, Glasgow, p41. 
  • Yong, P.H., Mat Junit, S., Harun, F. and Hashim, O.H. (2003) Patients with congenital hypothyroidism demonstrate differential expression of plasma fibrinogen and haptoglobin, 17th Asia Oceania Thyroid Assoc. Cong., Singapore, p63. 
  • Abdul Rahman, P.S., Shuib, A.S., Doustjalali, S.R., Lim, B.K., Othman, I. and Hashim, O.H. (2003) Profiling sera of patients with cervical carcinoma using proteomics technology, 28th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Putrajaya, p75. 
  • Doustjalali, S.R., Abdul Rahman, P.S., Shuib, A.S., Yusof, R., Othman, I., Yip, C.H., Looi, L.M. and Hashim, O.H. (2003) Lectin generated serum proteomes of patients with breast disorders, 28th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Putrajaya, p79. 
  • Muliawan, S.Y., Lam, S.K., Hashim, O.H. & Yusof R. (2003) Protein expression of dengue virus type 2 in two-dimensional gel electrophoresis, J Clin Virol, 28, S30. (ISI/SCOPUS Indexed Publication)
  • Muliawan, S.Y., Lam, S.K., Hashim, O.H. & Yusof R. (2003) Proteomics Study on the inhibitory effect of Quercus lusitanica against dengue virus type-2, 28th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Putrajaya, p95. 

2002
  • Doustjalali, S.R., Yusof, R., Looi, L.M., Yip, C.H., Govindasamy, G.K., Bustam, A.Z., Othman, I., and Hashim, O.H. (2002) Sera of patients with breast and nasopharyngeal carcinomas demonstrate differential two-dimensional electrophoretic proteome maps, 12th Sci. Meet. Mal. Soc. Mol. Biol Biotech., p103. 
  • Abdul Rahman, P.S.A., Yeoh, K.H.C. and Hashim, O.H. (2002) Separation of human serum glycoproteins by sequential immobilised lectin and hemin affinity chromatography, 12th Sci. Meet. Mal. Soc. Mol. Biol. Biotech., Kuala Lumpur, p97. 
  • Yong, P.H., Mat Junit, S., Harun, F. and Hashim, O.H. (2002) Serum protein expression maps of patients with congenital hypothyroidism: a preliminary investigation, 12th Sci. Meet. Mal. Soc. Mol. Biol. Biotech., Kuala Lumpur, p100. 
  • Abdul Rahman, P.S., Doustjalali, S.R., Lim, B.K., Othman, I. and Hashim, O.H. (2002) Human cervical cancer serum proteome: detection by silver staining and enzyme-conjugated champedak lectin, 27th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Kuala Lumpur, p18. 
  • Chen, Y., Lim, B.K., Othman, I. and Hashim, O.H. (2002) Serum protein expression maps of untreated patients with ovarian carcinoma, 27th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Kuala Lumpur, p52. 
  • Doustjalali, S.R., Yusof, R., Looi, L.M., Yip, C.H., Govindasamy, G.K., Bustam, A.Z., Othman, I. and Hashim, O.H. (2002) Serum proteome maps of treated patients with breast cancer and nasopharyngeal carcinoma, 27th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Kuala Lumpur, p70. 
  • Yong, P.H., Mat Junit, S., Harun, F. and Hashim, O.H. (2002) Patients with congenital hypothyroidism demonstrate up-regulated expression of a 50-kDa serum protein, 27th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Kuala Lumpur, p71. 
  • Jalaludin, A.A., Mohamed, E., Abdul Rahman, P.S., Doustjalali, S.R. and Hashim, O.H. (2002) Profiling lectin affinity separated nasopharyngeal carcinoma serum glycoproteins, 27th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Kuala Lumpur, p73. 

2001
  • Shuib, A.S., Chua, C.T., Ahmad, F., Othman, I., Lim, S.B., Abdul Rahman, M., Kanthimathi, M.S. and Hashim, O.H. (2001) Champedak seed lectins: their isolation, characterisation and application in biomedical research, Proc. RMK7 IRPA Res. Sem., 1, 264-267. 
  • Doustjalali, S.R., Yusof, R., Looi, L.M., Yip, C.H., Othman, I. and Hashim, O.H., (2001) The human breast cancer two-dimensional serum protein expression maps generated by silver staining and lectin detection. Proc. Nat. Biotech. Sem., 13, 387-389. 
  • Hashim, O.H., Abdul Rahman, M. and Othman, I. (2001) The interaction of champedak seed galactose-binding lectin with human serum glycoproteins. 11th Sci. Meet. Mal. Soc. Mol. Biol Biotech., Kuala Lumpur, p22. 
  • Abdul Rahman, M., Karsani, S.A., Othman, I. and Hashim, O.H., (2001) Champedak seed lectin-C: the N-terminal sequence of its subunits and its application in the isolation of human serum glycoproteins. 26th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Kuala Lumpur, p43. 
  • Doust Jalali, S.R., Yusof, R., Looi, L.M., Yip, C.H., Othman, I. and Hashim, O.H., (2001) The human breast cancer serum proteome: analysis by two-dimensional gel electrophoresis and silver staining. 26th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Kuala Lumpur, p24. 
  • Doust Jalali, S.R., Yusof, R., Looi, L.M., Yip, C.H., Othman, I. and Hashim, O.H., (2001) The human breast cancer serum proteome: analysis by two-dimensional gel electrophoresis and detection by enzyme-conjugated champedak seed lectin-C. 26th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Kuala Lumpur, p31. 
  • Hashim, O.H., Ahmad, F. and Devi, S. (2001) The application of champedak seed lectin-M in the study on the acute-phase response in patients with typhoid fever. 26th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Kuala Lumpur, p44. 

2000
  • Hashim, O.H., Ahmad, F. and Shuib, A.A. (2000) The application of champedak seed mannose-binding lectin in the detection and isolation of selective human serum glycoproteins. 25th Ann. Conf. Mal. Soc. Biochem. Mol. Biol., Kuala Lumpur, p12. 
  • Hashim, O.H., Ahmad, F. and Shuib, A.A. (2000) The application of champedak mannose-binding lectin in the detection and isolation of selective human acute-phase proteins. 10th Mal. Assoc. Clin. Biochem. Ann Meet., Kuala Lumpur, FP1, p21. 

1999
  • Hashim, O.H. (1999) Application of lectin technology in medicine, Health Sect. Rev. Conf., UMMC Kuala Lumpur, p63. 

1998
  • Shuib, A.S., Chua, C.T. and Hashim O.H. (1998) The charge of jacalin-bound and -unbound serum IgA1. Fed. Asian Oceanian Biochem. Mol. Biol. Meet., Kuala Lumpur, C35, 94. 
  • Ahmad, F, Hashim O.H. and Kanthimathi, M.S. (1998) Isolation of an N-acetyl-D-glucosamine-binding lectin from seeds of mango. Fed. Asian Oceanian Biochem. Mol. Biol. Meet., Kuala Lumpur, A31, 60. 
  • Abdul Rahman, M., Hashim O.H., Othman, I., Subramaniam, R. and Hassan, J. (1998) Detection of human chorionic gonadotropin hormone by using enzyme-conjugated lectin-C. Fed. Asian Oceanian Biochem. Mol. Biol. Meet., Kuala Lumpur, C34, p94. 
  • Rodgars, S.A., Hashim O.H., Yusof, R. and Junit, S.M. (1998) A suitable method for isolation of nucleic acid from freeze-dried seeds of jackfruit and champedak. Fed. Asian Oceanian Biochem. Mol. Biol. Meet., Kuala Lumpur, C33, p94. 

1997
  • Shuib, A.S., Chua, C.T. and Hashim O.H. (1997) Characterisation of jacalin-bound and -unbound serum IgA1. Fed. Asian Oceanian Biochem. Mol. Biol. Meet., Manila, Philippines, C 23. 
  • Lim S.B., Kanthimathi M.S., and Hashim O.H. (1997) Effect of champedak seed mannose-binding lectin on the proliferation of murine lymphocytes. Fed. Asian Oceanian Biochem. Mol. Biol. Meet., Manila, Philippines, PR 68. 
  • Hashim, O.H. (1997) Immunoglobulin-reactive lectins from champedak seeds, University of Malaya 1997 Research Colloquium, p13. 
  • Shuib, A.S., Chua, C.T. and Hashim, O.H. (1997) Analyses of sera of IgA nephropathy patients using two-dimensional gel electrophoresis chromatography and jacalin-blotting. 33rd Ann. Sci. Sem. Mal. Soc. Parasit. Trop. Med., p11. 
  • Lim, S.B., Chua, C.T. and Hashim, O.H. (1997) Interaction of a mannose-binding Artocarpus integer seed lectin with human IgE and IgM. 33rd Ann. Sci. Sem. Mal. Soc. Parasit. Trop. Med., p11. 

1996
  • Mestecky, J., Tomana, M., Julian, B., Hashim, O.H., Jensen, J. and Radi, J. (1996) IgA nephropathy: Defect of glycosylation of IgA1 molecules. Journal of Investigative Medicine, 44(3), A321. (ISI-Indexed)

1995
  • Mestecky, J., Tomana, M., Hashim, O.H., Brown, R., Kulhavy, R. and Julian, B.A. (1995) Altered glycosylation pattern of IgA1 in sera of IgA nephropathy patients, FASEB Journal, 9(3): A74. (ISI-Indexed)

1994
  • Hashim, O.H. (1994) Defective O-linked oligosaccharide structures of IgA1 molecules as a possible etiopathogenic factor of IgA nephropathy, 12th Europ. Immunol. Meet. Barcelona, Spain, p333. 
  • Hashim, O.H., Gendeh, G.S., Cheong, C.N. and Nik Jaafar, M.I. (1994) Consumption of guinea-pig complement activity by jackfruit and champedak lectins, 12th Europ. Immunol. Meet. Barcelona, Spain, p139. 
  • Hashim, O.H. and Chong, H.A.A.H. (1994) Detection of mannose-binding lectins in crude extracts of champedak and jackfruit seeds, Proc. Mal. Biochem. Mol. Biol. Soc. Conf., 19, 230-233. 

1992
  • Hashim, O.H. and Rahim, Z.H.A. (1992) Quantitative estimation of IgA1 using Artocarpus integer lectin - a preliminary investigation. Proc. Mal. Biochem. Soc. Conf., 17, 188-191. 

1991
  • Hashim, O.H., Devadason, V. and Hassan, H. (1991) Kinetics of IgA1 protease activity from broth culture supernatant of Clostridium septicum. Proc. Mal. Biochem. Soc. Conf. 16, 100-103. 

1990
  • Rahim, Z.H.A. and Hashim, O.H. (1990) Effect of molecular size of IgA on its quantitative assay by immunonephelometry. Proc. Mal. Biochem. Soc. Conf. 15, 162-163. 
  • Hashim, O.H., Ng, C.L. and Nik Jaafar, M.I. (1990) Jacalin-IgA interaction: existence of two binding sites? Proc. Mal. Biochem. Soc. Conf. 15, 164-165. 

1989
  • Hashim, O.H. and Nik Jaafar, M.I. (1989) IgA binding lectin from jackfruit seeds. Proc. Mal. Biochem. Soc. Conf. 14, 210-212. 
  • Hashim, O.H. and Cushley, W. (1989) Affinity interaction of N-linked oligosaccharide structures of IgG2b with Concanavalin A. Proc. Mal. Biochem. Soc. Conf. 14, 217-219. 

1988
  • Hashim, O.H. and Cushley, W. (1988) Inhibition of N-linked oligosaccharide processing of IgG leads to potentiated complement fixation. Proc. Fed. Asian Oceanian Biochem. Symp. 7, 95-96. 
  • Wood, A., Jaques, A.M., Hashim, O.H. and Cushley, W. (1988) The role of N-linked oligosaccharides in control of expression of effector functions of a rat IgG2b monoclonal antibody. British Society for Immunology Summer Meeting, University of Strathclyde, Scotland. 38, 68-69. 

1986
  • Jones, J.A., Hashim, O.H., Wood, A. and Cushley, W. (1986) Immunochemical recognition of tyrosine phosphate and tyrosine sulphate. 6th International Congress of Immunology, Toronto, Canada. 2.73.12. 


AREAS OF RESEARCH
(Project title), (Role), (From)-(Until), (Source), (Level).


  • Proteomics, Cancer, Lectins, Glycosylation
  • Functional Proteomic Analysis of Circadian Clock Gene Products in Drosophila and Mammalian Systems, Co-Researcher, 11/11/2013, Geran Penyelidikan Universiti Malaya (Umrg Programme) - Htm (Wellness), 31/12/2016
  • Functional Proteomic Analysis of Circadian Clock Gene Products in Drosophila and Mammalian Systems, Principal Investigator(Pi), 11/11/2013, Geran Penyelidikan Universiti Malaya (Umrg Programme) - Htm (Wellness), 31/12/2016
  • Frailty Among in-Patients in Geriatric Medicine, Co-Investigator, 2012-2015, Geran Penyelidikan Universiti Malaya (Umrg), National
  • 1.Proteomic Explanation On The Effect of Ficus Deltoidea Extract Towards The Characteristics of The Reproductive Organ of Rats 2. Deregulated Protein Expression in Selected Cancer Cell Lines Post-Treatment With Pereskia Bleo Aqueous Extract and Fraction, Co-Investigator, 2012-2015, Postgraduate Research Grant(Ppp), National
  • The Use of Acute Phase Reactant Proteins as Cancer Biomarkers, Principal Investigator(Pi), 2011-2015, High Impact Research (Hir), National
  • Glycoproteomic Analysis of Human and Mammalian Milk : a Lectin-Based Approach, Co-Investigator, 2010-2012, Fundamental Research Grant Scheme (Frgs), National
  • Exploring Salivary Proteins With Potential Application as Biomarkers in Clinical Diagnosis, Co-Investigator, 2009-2012, Geran Penyelidikan Universiti Malaya (Umrg), National
  • Serum Expression Proteomics of Patients With Nasopharyngeal Carcinoma., Principal Investigator(Pi), 2007-2010, Imr/Moh Malaysia, International
  • Application of Proteomic Techniques For Bioactivity Evaluation and Protein Profiling of Ficus Deltoidea, Co-Investigator, 2007-2009, Mosti, University
  • Serum Proteomics of Patients With Gestational Trophoblastic Diseases, Principal Investigator(Pi), 2007-2009, Geran Penyelidikan Universiti Malaya (Umrg), University
  • Lectin-Based Approach in Proteomic Studies, Principal Investigator(Pi), 2006-2008, Sciencefund, International
  • Application of Lectin Technology in Medicine., Principal Investigator(Pi), 2002-2006, Mosti (Irpa), International

AWARDS AND RECOGNITIONS
(Name of Award), (Awarding Institution), (Year Awarded), (Level).


  • Visiting Professor, Prince of Songkla University, Thailand, 2016, (International)
  • Certificate of Excellent Service, 2014
  • Excellence Service Award, 2012
  • Khidmat Setia 20 Award, 2008
  • National Academic Award 2007 Journal Article Publication Category., Ministry of Higher Education, Malaysia, 2008, (National)
  • Excellence Service Award, 2008
  • Excellence in Service Award For Year 2007, University of Malaya, 2008, (University)
  • Service Loyalty Award (Twenty Years), University of Malaya, 2008, (University)
  • Certificate of Excellent Service, 2007
  • Certificate of Excellent Service, 2006
  • Excellent Scientist (Certificate of Merit), Ministry of Higher Education, Malaysia, 2005, (National)
  • Excellence in Service Award For Year 2004, University of Malaya, 2005, (University)
  • Gold Medal, 33rd International Exhibition of Inventions, Technology and New Products, Geneva, 2005, (International)
  • Gold Medal, University of Malaya Science, Research and Innovation Exposition, 2004, (University)
  • Silver Medal, National Science, Research and Innovation Exposition, 2004, (National)
  • Excellence in Service Award For Year 2000, University of Malaya, 2001, (University)
  • Certificate of Merit For Best Presentation, University of Malaya Medical Centre (Irpa Health Sector Conference), 1999, (University)
  • Best Stage I Lecturer Award, Medsoc, University of Malaya (Voted by 1996/97 Batch of Mbbs Students), 1997, (University)
  • Fulbright Scholar Award, J.W. Fulbright Board of Foreign Scholarships, Usa, 1993, (International)
  • Jsps Research Fellowship, Japan Society For The Promotion of Science, 1991, (International)

PRESENTATIONS
(Title), (Event), (Date Presented), (Organiser), (Level).


Pleanary/keynote Speaker
  • Champedak lectins: from the humble seed to targeted proteomics., 37th Annual Conference of the Malaysian Society for Biochemistry and Molecular Biology, Sime-Darby Convention Centre, KL., 18 Jul 2012, Malaysian Society for Biochemistry and Molecular Biology., (National)
  • Studying a study: a reviewer's perspective., INFORMM Colloquium and Scientific Wrting Workshop, 10 Oct 2009 to 10 Oct 2009, INFORMM, USM, (National)
  • Translating research into manuscript: points to consider., Manuscript Writing Retreat Workshop, 11 Dec 2009, USM, (National)
  • Lectins from the seeds of champedak: from waste to wonders., 29th Annual Conference of the Malaysian Society for Biochemistry and Molecular Biology., 01 Sep 2004, Malaysian Society for Biochemistry and Molecular Biology., (National)
Invited Seminar
  • The art of publishing: sharing of experiences, Departmental Seminar, 08 Apr 2016 to 08 Apr 2016, Department of Biochemistry, Prince of Songkla University, Thailand, (International)
  • Gel-based Cancer Proteomics: Studies at UMCPR, Departmental Seminar, 07 Apr 2016 to 07 Apr 2016, Department of Biochemistry, Prince of Songkla University, Thailand, (International)
  • Translating research into manuscripts., Post-graduate students Seminar, Department of Molecular Medicine, UM., 24 Apr 2013, Post-Graduate Students' Club, (University)
  • The Art of Publishing., Seminar on Publication, Faculty of Medicine, Royal College of Medicine Perak, UniKL, Ipoh., 27 Jun 2013, Royal College of Medicine Perak, UniKL., (National)
  • The art and science of publishing., Publish or Perish Seminar, AMDI, USM, Kepala Batas., 18 Jun 2012, Advance Medical and Dental Institute, Universiti Sains Malaysia., (National)
  • Champedak seed lectins: the past, the present and the future., Faculty seminar, UMS, Kota Kinabalu, 10 Mar 2011, Faculty of Medicine, Universiti Malaysia Sabah, (University)
  • Studies of the champedak seed lectins: the past, the present and the future., Faculty Seminar, Faculty of Medicine, UNIMAS, Kuching, 27 May 2009, (Others)
  • Champedak seed lectins, Faculty Seminar, Faculty of Medicine, USIM, 16 Apr 2008, Faculty of Medicine, USIM, (University)
  • Champedak seed lectins: from waste to wonders., Faculty Seminar, 01 Apr 2004, Faculty of Medicine, Universiti Teknologi MARA., (National)
  • Immunoglobulin-reactive lectins from champedak seeds., Faculty Seminar, 01 Jun 1996, Department of Oral Biology, UM., (University)
  • Immunoglobulin-reactive lectins from champedak seeds., Department Seminar, 07 Mar 1995, Department of Physiology, Faculty of Medicine, University of Malaya, (University)
  • Asparagine-linked oligosaccharides of immunoglobulin A, Department Seminar, 02 Jul 1991, Department of Biochemistry, Osaka University Medical School, Osaka, Japan, (International)
  • IgA-reactive lectins from Artocarpus seeds, Department Seminar, 11 Jul 1991, Cancer Institute, Hokkaido University School of Medicine, Sapporo, Japan, (International)
  • IgA-reactive lectins from Artocarpus seeds, Department Seminar, 15 May 1991, Department of Biochemistry, Osaka University Medical School, Osaka, Japan, (International)
  • Jacalin: isolation, characterisation and application, Department Seminar, 11 Sep 1990, Department of Medical Microbiology, Faculty of Medicine, University of Malaya, (University)
  • IgA-binding lectins from Artocarpus species, Department Seminar, 11 Dec 1990, Department of Microbiology, Faculty of Medicine, Universiti Kebangsaan Malaysia, (National)
Invited Speaker
  • The use of urinary inter-alpha trypsin inhibitor peptides as biomarkers to discriminate benign prostatic hyperplasia from prostate cancer, 2nd International Caparica Conference on Urinomics and Translational Nephrology, 28 Sep 2015 to 30 Sep 2015, (International)
  • The art of publishing., Seminar on Publication, Faculty of Medicine, Royal College of Medicine Perak, UniKL, Ipoh., 20 Oct 2015, Royal College of Medicine Perak, UniKL, Ipoh., (National)
  • Potential use of inter-alpha trypsin inhibitor peptides as biomarkers to discriminate prostate cancer from benign prostatic hyperplasia, 8th World Cancer Congress - 2015, 15 May 2015 to 17 May 2015, World Cancer Congress, (International)
  • The art of publishing., Seminar on Publication, Faculty of Medicine, Royal College of Medicine Perak, UniKL, Ipoh., 27 Aug 2014, Royal College of Medicine Perak, UniKL, Ipoh., (National)
  • Potential use of inter-alpha trypsin inhibitor glycopeptides as cancer biomarker, 4th International Biochemistry and Molecular Biology Conference, Bangkok, 02 Apr 2014 to 03 Apr 2014, Kasetsart University, Thailand., (International)
  • Serum and urinary inter-alpha trypsin inhibitor glycopeptides as biomarker for prostate cancer, 19th World Congress on Advances in Oncology and 17th International Symposium on Molecular Medicine, Athens, 11 Oct 2014, Spandidos Publications, (International)
  • Pros and cons of inter-alpha trypsin inhibitor H4 fragment as cancer biomarker., Proteomics Forum, 10th Australian Peptide Conference., 08 Sep 2013, Australian Peptide Association, (International)
  • Gel- and lectin-based proteomics studies in search for novel biomarkers for cancer., Academia Sinica - University of Malaya International Workshop., 24 Feb 2011, Academia Sinica Taiwan & University of Malaya., (International)
  • Proteins: the good, the bad and the ugly., HTMC Teh Tarik Club Talk., 21 Jul 2010, HTMC, (University)
  • Writing research manuscripts for the allied health sciences., Seminar on Publishing Your Research Findings., 24 Mar 2010, Health and Translational Medicine Research Cluster, (University)
  • Applications of proteomics in medicine, 2DE-MS Proteomics Seminar, 23 Feb 2010, Monash University, (National)
  • Cancer biomarkers from the proteome., 35th Ann. Conf. Mal. Soc. Biochem. Mol. Biol. Conf.,, 27 Jul 2010, Malaysian Society for Biochemistry and Molecular Biology & CARIF, (National)
  • Acute-phase protein response: can it be used as a diagnostic tool for cancer?, BIT Life Sciences 2nd Annual Protein and Peptide Conference (PepCon-2009),Seoul, Korea., 03 Apr 2009, BIT Life Sciences
  • Proteomics of cancer, Academy of Medicine Symposium, 07 Sep 2007, Academy of Medicine and the Ministry of Health Malaysia, (National)
  • Proteomics studies of cancer., 2nd International University of Malaya Research Imaging Symposium., 01 Jul 2005, Continuing Radiological Education, University of Malaya Medical Centre., (International)
  • Preparation and Delivery of Biochemistry lectures in the MBBS Course., 2nd Biochemical Education Workshop., 01 Jun 2005, Department of Molecular Medicine, UM., (University)
  • Preparation and delivery of biochemistry lectures in the MBBS Course., Workshop on the Teaching of Biochemistry in the MBBS Course, 16 May 2000, (University)
  • Protein chemistry and enzyme function., Training course on Industrial applications of structure-based molecular design and combinatorial chemistry., 01 Jul 1997, UM, United Nations Indust. Dev. Org. and Int. Centre for Sci. and High Techn., (International)
Event Organiser
  • Selective past proteomics studies at the University of Malaya Centre for Proteomics Research (UMCPR)., UMCPR Research Day and Proteomics Workshop, Faculty of Medicine, UM., 21 Jun 2012, UMCPR, (National)
Oral
  • Gel- and lectin-based serum proteomics profiling in search for new complementary biomarkers for cancer., National Biotechnology Conference, 26 May 2010, MOSTI, (National)
  • Acute-phase protein response: can it be used as a diagnostic tool for cancer?, Departmental Seminar, 15 Apr 2009, (University)
  • Potential role of ceruloplasmin as a novel biomarker for diagnosis and monitoring of nasopharyngeal carcinoma., 7th Federation of Asian and Oceanian Biochemist Symposium., 01 Nov 2004, International Union of Biochemistry., (International)
  • The interaction of champedak seed galactose-binding lectin with human serum glycoproteins., 16th Scientific Meeting of the Malaysian Society for Molecular Biology and Biotechnology., 01 May 2001, Malaysian Society for Molecular Biology and Biotechnology., (National)
  • Champedak seed lectins: their isolation, characterisation and application in biomedical research., RMK7 IRPA Conference, 19 Jul 2001, (University)
  • The application of champedak lectin in the detection and isolation of selective human acute-phase proteins., 10th scientific meeting of the Malaysian Association of Clinical Biochemists., 01 Aug 2000, Malaysian Association of Clinical Biochemists., (National)
  • The application of champedak seed mannose-binding lectin in the detection and isolation of human serum glycoproteins., 25th Annual Conference of the Malaysian Society for Biochemistry and Molecular Biology., 01 Oct 2000, Malaysian Society for Biochemistry and Molecular Biology., (National)
  • Application of lectin technology in medicine., IRPA Health Sector Review Conference, 09 Sep 1999, (University)
  • Immunoglobulin-reactive lectins from champedak seeds, University of Malaya Research Colloquium, 16 Jul 1997, (University)
  • Inhibition of N-linked oligosaccharide processing of IgG leads to potentiated complement fixation., 7th Federation of Asian and Oceanian Biochemist Symposium, 24 Nov 1988, 7th Federation of Asian and Oceanian Biochemist Symposium, (International)
Presenter
  • Selective past proteomics studies at UMCPR., APAF-UMCPR Meeting, Department of Molecular Medicine, UM., 24 Sep 2012, UMCPR, (University)
  • Small group teaching: how to conduct tutorial and problem solving sessions., Medical Biochemistry Teaching Workshop, Department of Molecular Medicine, UM., 30 Oct 2012, Department of Molecular Medicine, (University)
  • Cempedak and an immunochemist: what is the connection?, Inaugural Lecture, 05 Feb 2008, ICR, UM, (University)
  • MJBMB: a session with the Editor-in-Chief, 33rd Annual Conference of the Malaysian Society for Biochemistry and Molecular Biology, 28 Aug 2008, Malaysian Society for Biochemistry and Molecular Biology, (National)
  • Overview of basic research in biomedical sciences, Seminar and Discussion with Nobel Laureate Prof. Ahmed H. Zewail, 07 Aug 2007, University of Malaya, (University)
  • Champedak lectins: application in biomedical research, Department Seminar, 22 Feb 2006, Department of Molecular Medicine, (University)

SUPERVISION


Post Graduate Level
(Name of Degree), (Name of Candidates), (Title of Thesis), (Academic Session)

Completed
  • Masters Degree, Anil Azura Jalaludin, Application of galactose-binding champedak lectin in the isolation and detection of serum glycoproteins., 2002/2003
  • Masters Degree, Chai Hwa Chia, Proteome analysis and identification of immunogenic proteins of Cryptococcus neoformans, 2005/2006
  • Masters Degree, Emida Mohamed, Application of mannose-binding champedak lectin in the isolation and detection of serum glycoproteins., 2002/2003
  • Masters Degree, Faizah Ahmad, Characterisation and application of mannose-binding lectin from the seeds of champedak., 2000/2001
  • Masters Degree, Mariati Abdul Rahman, Characterisation and application of galactose-binding lectin from the seeds of champedak., 2000/2001
  • Doctoral Degree (PhD), Vanitha Mariappan, Pathogenicity of secreted extracellular proteins in Bukholderia cenocepacia Malaysian isolates using Bioinformatic tools., 2007/2008
  • Masters Degree, Yong Phaik Har, Plasma protein expression profiles and PAX8 gene mutation(s) screening of patients with congenital hypothyroidism., 2003/2004
  • Doctoral Degree (PhD), Chen Yeng, Expression of proteins in sera and tissues of patients with ovarian carcinoma., 2005/2006
  • Doctoral Degree (PhD), Emida Mohamed, Proteomics studies of patients with gestational trophoblastic disease., 2008/2009
  • Doctoral Degree (PhD), Norhaniza Aminudin, Euricoma longifolia aqueous extract-bioactive compound and its effects toward hormone production and spermatogenesis., 2002/2003
  • Doctoral Degree (PhD), Puteri Shafinaz Akmar Abdul Rahman, Application of lectins in studies of protein expression in patients with cervical and endometrial cancer., 2006/2007
  • Doctoral Degree (PhD), Saeid Reza Doust Jalali, Proteins expression in patients with malignant and benign breast tumours., 2003/2004
  • Doctoral Degree (PhD), Kumutha Malar Vellasamy, Studies of Burkholderia pseudomallei and B. thailandensis, 2007/2008
  • Doctoral Degree (PhD), Jameel Rabee Al-obaidi, Interaction between E. guineensis and G. boninense causing basal stem rot, 2007/2008
  • Masters Degree, Ramarao Seriramalu, Proteomic studies of patients with nasopharyngeal carcinoma, 2008/2009
  • Doctoral Degree (PhD), Jessie Kala Rayappan Thomas, Proteome profiling of human saliva of cigarette smokers and non-smokers, 2008/2009
  • Masters Degree, Adawiyah Suriza Shuib, The application of lectins in the study of serum IgA1 from IgA nephropathy patients, 1997/1998
  • Masters Degree, Gurmil Singh Gendeh, IgA binding lectins from Artocarpus integer, 1990/1991
  • Masters Degree, Lim Sing Bin, Mannose-binding lectin from seeds of Artocarpus integer, 1996/1997
  • Masters Degree, Shahram Golbabapour, Proteomics profiling of sera of rats chemically induced with cancer., 2008/2009
  • Doctoral Degree (PhD), Alan Mu Kang Wai, Lectin-based proteomic studies of urinary proteins from patients with endometrial, ovarian and cervical cancer., 2012/2013
  • Doctoral Degree (PhD), Jaime Jaqueline Jayapalan, Identification of potential serum and urine biomarkers for patients with prostate cancer using lectin-based proteomic analyses, 2013/2014

Ongoing
  • Doctoral Degree (PhD), Mardiaty Abdullah, Various proteomics investigations of patients with thyroid cancer., 2013/2014
  • Doctoral Degree (PhD), Lee Cheng Siang, Study of mucin-type O-glycoproteins using lectins., 2013/2014
  • Masters Degree, Mohd Aizat Abdul Rahim, Saliva proteomics, 2013/2014
  • Doctoral Degree (PhD), Mohammad Faujul Kabir, Proteomics aspects of Studies of Extracts from Belalai Gajah, 2015/2016
  • Masters Degree, Wong Sing Ying, Proteomics of Hair Shaft Proteins, 2015/2016
  • Doctoral Degree (PhD), Lim Chor Yin, Proteomics aspects of Tamarindus indica, 2014/2015
  • Doctoral Degree (PhD), Khaniza Hasliza Binti Abdul Khalil, Proteomics aspects of Ficus deltoidea, 2012/2013

INTELLECTUAL PROPERTY RIGHTS
(Product Name), (Type), (Reference), (Year), (Level).


  • A method for detecting the 35kDa O-glycosylated inter-alpha-trypsin inhibitor heavy chain H4 fragments., Patent, PI 2008 4944, 2008, (National)
  • Hashim, O.H. and Shuib, A.S. (2004) Lectin-based pregnancy test kit (method for detecting hCG hormone and test kit thereof) , Patent, PI20041268

EXPERT LINKAGES
(Linkages Description), (Organisation), (Year of Involvement), (Duration), (Level).


  • Project on proteomic studies of serum from patients with nasopharyngeal carcinoma., Molecular Pathology Unit, Cancer Research Centre, Institute for Medical Research, Malaysia., 2007, 36, (National)
  • Project on crystallisation of champedak seed lectins, Glasgow Biomedical Research Centre, University of Glasgow, 2008, 36, (International)

EXPERT/TECHNICAL CONTRIBUTIONS
(Activity), (Organisation), (Role), (From)-(Until), (Level).


  • External Examiner of the Biochemistry programme of the Bachelor of Medicine & Bachelor of Surgery (MBBS) Course, MARA University of Teknology, Expert Advisor, 2004, (University)
  • Consultant on lectin-based projects, Forest Research Institute Malaysia, Cargill Malaysia Sdn. Bhd. and Ema Consultancy Sdn. Bhd., Consultant , 2006, (National)
  • Panel evaluator (Technical) for monitoring and evaluation of R&D Science Fund Research Projects (Biotechnology), Ministry of Science, Technology and Innovation, Malaysia., Technical Advisor, 2007-2008, (National)
  • External Examiner of the Biochemistry programme of the Bachelor of Medicine & Bachelor of Surgery (MBBS) Course, Islamic Science University of Malaysia, Expert Advisor, 2008, (National)
  • Accreditation Panel Member (Medical Biochemistry), Malaysian Qualificaions Agency (MQA), Expert Advisor, 2008-2012, (National)
  • External Examiner of the Biochemistry programme of the Bachelor of Medicine & Bachelor of Surgery (MBBS) Course, Melaka Manipal Medical College, Manipal, India, Expert Advisor, 2008, 2009, 2010, (International)
  • External Examiner of the Biochemistry programme of the Bachelor of Medicine & Bachelor of Surgery (MBBS) Course, International Medical University, Expert Advisor, 2008, 2010, (National)
  • External Academic Advisor, School of Biosciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Expert Advisor, 2009, (National)
  • External Examiner of the Biochemistry programme of the Bachelor of Medicine & Bachelor of Surgery (MBBS) Course, Universiti Malaysia Sarawak, Expert Advisor, 2009, (National)
  • External Examiner of the Biochemistry programme of the Bachelor of Dental Surgery (BDS) Course, MARA University of Technology, Expert Advisor, 2009, (National)
  • External Examiner of the Biochemistry programme of the Bachelor degree of Doctor of Medicine (MD) Course, Universiti Kebangsaan Malaysia, Expert Advisor, 2009, (National)
  • External Examiner of the Biochemistry programme of the Bachelor of Medicine & Bachelor of Surgery (MBBS) Course, Universiti Malaysia Sabah, Expert Advisor, 2011-2012, (National)
  • External Examiner of the Biochemistry programme of the Bachelor of Dental Surgery (BDS) Course, International Islamic University Malaysia,, Expert Advisor, 2011-2012, (National)
  • External Examiner for the Biochemistry programme of the Bachelor of Medicine & Bachelor of Surgery (MBBS) Course of CUCMS, Cyberjaya University College of Medical Sciences, Expert Advisor, 2012-2012, (National)
  • External Examiner of the Biochemistry programme of the Bachelor of Medicine & Bachelor of Surgery (MBBS) Course, Melaka Manipal Medical College, Manipal, India, Expert Advisor, 2013-2013, (International)
  • External Examiner of the Biochemistry programme of the Bachelor degree of Doctor of Medicine (MD) Course, Universiti Pertahanan Nasional Malaysia, Expert Advisor, 2013-2013, (National)

EVALUATION ACTIVITIES
(Description), (Evaluation Activity),(Year).


  • Reviewer of scientific manuscripts for peer-reviewed international journals: Electrophoresis, PLoS ONE, Journal of Cancer Research and Clinical Oncology, International Journal of Cancer, Proteomics, Cancer Cell International, and Bioorganic & Medicinal Chemistry Letters., Article , 
  • Mechanisms of action of vitamin E (-tocopherol dan -tocotrienol) and hydrogen peroxide on liver cancer cells, HepG2 (PhD, UKM 2007)., Thesis , 
  • Euricomanone demonstrates anti-proliferative activity through apoptosis in MCF-7 cells (PhD, UKM 2005)., Thesis , 
  • Molecular cloning, expression, purification and functional implications of recombinant cytokines (PhD, IITG India, 2014)., Thesis ,  (2014)
  • Mechanism of beta amyloid peptide toxicity on neuron cells and its modulation by tocotrienol rich fraction (MMedSc, UKM, 2014), Thesis ,  (2014)
  • Anti-cancer and anti-angiogenic mechanisms of panduratin A isolated from Boesenbergia rotunda, Thesis ,  (2014)
  • A study of Acinetobacter baumannii pili gene and its expression in response to imipenem (PhD, UM, 2013)., Thesis ,  (2013)
  • Characterization of Entamoeba histolica antigens in pus aspirate and serum of patients with amoebic liver abscess (PhD, USM, 2012), Thesis ,  (2012)
  • Induction of cytochrome C mediated apoptosis by goniothalamine on human breast cancer cells MCF-7 (MSc, UKM 2004)., Thesis , 
  • Effects of palm vitamin E suplementation on the oxidative status in the formation of steroid-induced cataract (MSc, UKM 2004)., Thesis , 
  • Studies on the hyaluronidase enzyme purified from the venom of Chinese red scorpion Buthus martensi Karsch (PhD, National University of Singapore, 2009)., Thesis , 
  • Detection and Characterization of Circulating Toxoplasma gondii Antigens and Host Specific Proteins in Toxoplasmosis via Serum Proteomic Approach (PhD, USM, 2010)., Thesis , 
  • Identification of putative target and ligand molecules of tocotrienols in MCF-7 human breast cancer cells (MSc, IMU 2010), Thesis ,  (2010)
  • In vitro studies of zerumbone, a natural plant product with chemotherapeutic potential for ovarian and cervical cancers (MSc,UPM 2005)., Thesis , 
  • The effects of stress on lactation among working and non-working Malaysian mothers, Thesis ,  (2014)
  • Generation and characterisation of anti thymidine kinase 1 antibody as a potential tumour marker (MSc, UKM 2006)., Thesis , 
  • Antiproliferative effects and safety evaluation of Euricoma longifolia jack (Tongkat Ali) extracts (MSc, UKM 2003)., Thesis , 
  • Identification of potential protein biomarkers from S. typhi biofilm (MSc, USM, 2013), Thesis ,  (2013)
  • Development of a proteome map and identification of potential protein markers for gestational diabetes mellitus (MSc, UPM, 2012)., Thesis ,  (2012)
  • MicroRNAs in diabetes mellitus and metabolic syndrome (PhD, NUS, 2012)., Thesis ,  (2012)
  • In vivo study of the effects of angiogenic supression and protein kinase C inhibition on breast cancer (MSc, USM, 2012)., Thesis ,  (2012)
  • Identification of immunogenic proteins extracted from sera from individuals infected by Plasmodium knowlesi (MSc, USM, 2012)., Thesis ,  (2012)
  • Monitoring and Evaluation of R&D Science Fund Research Projects (Biotechnology), MOSTI., Project , 
  • External evaluator (Health Sector) for Research and Innovation Expositions, Universiti Kebangsaan Malaysia (2004 & 2005)., Project , 
  • Malaysian Journal of Biochemistry and Molecular Biology, 2006-2009., Article In Journal , 
  • Promotion/intake exercise of Professors and/or Associate Professors for Universiti Kebangsaan Malaysia, Universiti Putra Malaysia, Universiti Sains Malaysia, Universiti Sains Islam Malaysia, International Medical University and Monash University Sunway Campus., External Assessor , 
  • Panel Evaluator of research proposals and panel interviewer for National Science Fellowship (2007)., Candidate Evaluation , 
  • Promotion/Intake Exercise, UKM, UPM, USM, USIM and IMU., Staff Achievements , 

CONTRIBUTION TO SOCIETY
(Contribution To Society), (Level), (Start Date), (End Date).


  • Presented a seminar on The art of publishing research manuscripts: sharing of experiences. Department of Molecular Medicine, December 2016., (Department), 2016-12-14 until 2016-12-14
  • Invited Speaker on Cancer biomarker discovery: lectin-based proteomic studies. Department of Microbiology and Immunology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, October 2016., (National), 2016-10-20 until 2016-10-20
  • Panel Evaluator of the Curriculum Review of the Bachelor of Biomolecular Sciences Programme (AS244) of the Faculty of Applied Sciences, Universiti Teknologi MARA, September 2016., (National), 2016-09-08 until 2016-09-08
  • Grant Proposal Reviewer, Croatian Science Foundation (HRZZ), Croatia., (International), 2016-09-06 until 2016-09-29
  • Grant Proposal Reviewer, Medical Research Council (MRC), United Kingdom., (International), 2016-08-15 until 2016-09-05
  • Invited Speaker on Cancer biomarker discovery: lectin-based proteomic studies. Department of Molecular Medicine Research Day, Faculty of Medicine, University of Malaya, May 2016., (Ptj), 2016-05-31 until 2016-05-31
  • Visiting Professor, Department of Biochemistry, Faculty of Science, Prince of Songkla University, Hat Yai, Thailand, March April 2016., (International), 2016-03-28 until 2016-04-08
  • Head, University of Malaya Centre for Proteomics Research (UMCPR), 2016 2017., (University), 2016-01-01 until 2017-12-31
  • Head, University of Malaya Centre for Proteomics Research (UMCPR), 2016 2017., (University), 2016-01-01 until 2017-12-31
  • Chairman, Category of Journal Article Publication, National Academic Award Selection Committee. , (National), 2015-12-09 until 2016-12-31
  • National Academic Award 2014 & 2015 Selection Committee, (National), 2015-01-01 until 2016-12-31
  • Chairman, Panel Interviewer (Medical and Health Sciences) for Yang Dipertuan Agong Scholarship appointed by Public Services Department, Malaysia., (National), 2014-08-20
  • Member, Editorial Board, Journal of the University of Malaya Medical Centre (JUMMEC)., (National), 2014-05-01 until 2016-04-30
  • National Academic Award 2013 Selection Committee, (National), 2014-01-01 until 2014-12-31
  • Chairman, Panel Interviewer (Medical and Health Sciences) for Yang Dipertuan Agong Scholarship appointed by Public Services Department, Malaysia., (National), 2013-09-04
  • National Academic Award 2012 Selection Committee, (National), 2013-01-01 until 2013-12-31
  • Editorial Board member, Biomarker Research., (International), 2012-08-16 until 2017-08-15
  • Expert Panel for Evaluation of Funding for Research, Development and Commercialisation, appointed by MOSTI., (National), 2012-03-01 until 2015-12-31
  • National Academic Award 2011 Selection Committee, (National), 2012-01-01 until 2012-12-31
  • National Academic Award 2010 Selection Committee, (National), 2011-01-01 until 2011-12-31
  • Expert Panel for Evaluation of Funding for Research, Development and Commercialisation, appointed by MOSTI., (National), 2010-07-14 until 2012-07-13
  • Road-show for the National Academic Award 2009 - Journal Article Publication Category, PICC., (National), 2010-04-29
  • Member, Editorial Board, Journal of the University of Malaya Medical Centre (JUMMEC)., (University), 2010-02-01 until 2013-01-31
  • National Academic Award 2009 Selection Committee, (National), 2010-01-01
  • Panel member of the MBMMBI Meeting on feedback on strengthening of the teaching of English, Ministry of Education (2009)., (Country), 2009-08-03
  • National Academic Award 2008 Selection Committee, (National), 2009-02-10
  • Committee Member, National Strategic Sector Advisory Committee (Biotechnology), appointed by MOHE., (National), 2007-08-15 until 2009-07-14
  • Editor-in-Chief of the Malaysian Journal of Biochemistry and Molecular Biology (2006 2009)., (National), 2006-01-02 until 2009-12-31
  • Chairman of Scientific Sub-committee of the 28th Malaysian Society for Biochemistry and Molecular Biology Annual Conference (2003)., (National), 2003-09-18
  • Chairman of Scientific Sub-committee of the 27th Malaysian Society for Biochemistry and Molecular Biology Annual Conference (2002)., (National), 2002-09-20
  • Organising Committee Member of the 26th Malaysian Society for Biochemistry and Molecular Biology Annual Conference (2001)., (National), 2001-09-20
  • Member, Editorial Board of the Malaysian Journal of Biochemistry and Molecular Biology, (National), 2000-01-03 until 2005-12-30
  • Secretary, 14th Malaysian Biochemical Society Conference. , (National), 1989-08-17
  • Organising Committee Member, Education and Teaching of Biochemistry Workshop, sponsored by International Union of Biochemistry., (Local), 1988-08-19