Curriculum Vitae

DR. NUR AKMARINA BINTI MOHD SAID

Pharmacy Lecturer
  • Department of Pharmaceutical Life Sciences
    Faculty of Pharmacy
  • +60379677520

AREAS OF EXPERTISE

  • GENOMIC
    Cancer metastasis, tumor microenvironment, miRNA biology, chemoresistance

ACADEMIC QUALIFICATION

  • SARJANA MUDA FARMASI, (Pharmacy)
    Universiti Malaya (UM)
  • PhD, (Molecular Biotechnology / Pharmacogenetic)
    Monash University, Australia
  • MSc, (Molecular Biotechnology / Pharmacogenetic)
    Monash University, Australia

ADMINISTRATIVE DUTIES

  • Head of Department
    16 Sep 2019 - 15 Sep 2021 (Department of Pharmaceutical Life Sciences, Faculty of Pharmacy)
  • Manager
    01 Jan 2019 - 31 Dec 2019 (Department of Pharmacy, Faculty of Medicine)
  • Head of Unit
    10 Jul 2015 - 27 Dec 2019 (Department of Pharmacy, Faculty of Medicine)

MEMBERSHIPS

  • TOPIC EDITOR FOR FRONTIERS IN PHARMACOLOGY, RESEARCH TOPIC., EDITORIAL BOARD
    2022 to 2022 (International)
  • REGISTERED PHARMACIST, MEMBER
    2020 to 2020 (National)

PUBLICATIONS

Article in Journal
WoS
  1. Kanmalar, M.; Sani, Siti Fairus Abdul; Kamri, Nur Izzahtul Nabilla B.; Said, Nur Akmarina B. M.; Jamil, Amirah Hajirah B. A.; Kuppusamy, S.; Mun, K. S.; Bradley, D. A. (2022). Raman spectroscopy biochemical characterisation of bladder cancer cisplatin resistance regulated by FDFT1: a review, CELLULAR & MOLECULAR BIOLOGY LETTERS. 27(1). doi:10.1186/s11658-022-00307-x
  2. Mozihim, Azilleo Kristo; Chung, Ivy; Said, Nur Akmarina B. M.; Abd Jamil, Amira Hajirah (2022). Reprogramming of Fatty Acid Metabolism in Gynaecological Cancers: Is There a Role for Oestradiol?, METABOLITES. 12(4). doi:10.3390/metabo12040350
  3. Paramanantham, Yogaambikai; Chung, Ivy; Said, Nur Akmarina B. M. (2022). The role of tumour microenvironment-driven miRNAs in the chemoresistance of muscle-invasive bladder cancer-a review, UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS. 40(4), 133-148. doi:10.1016/j.urolonc.2022.01.013
  4. Voon, Yap Chee; Omar, Intan Sofia; Wu, Ming-Heng; Said, Nur Akmarina; Chung, Ivy (2022). Cancer-associated fibroblasts as cellular vehicles in endometrial cancer cell migration, ONCOLOGY LETTERS. 23(1). doi:10.3892/ol.2021.13121
  5. Nor, W., Chung, I., & Said, N. (2021). MicroRNA-548m Suppresses Cell Migration and Invasion by Targeting Aryl Hydrocarbon Receptor in Breast Cancer Cells. Oncology Research, 28(6), 615-629. doi: 10.3727/096504020x16037933185170
Others
  1. Skalamera, D., Dahmer-Heath, M., Stevenson, A., Pinto, C., Shah, E., Daignault, S., Said, N., Davis, M., Haass, N., Williams, E., Hollier, B., Thompson, E., Gabrielli, B., & Gonda, T. (2016). Genome-wide gain-of-function screen for genes that induce epithelial-to-mesenchymal transition in breast cancer. Oncotarget, 7(38), 61000-61020.
  2. Elizabeth D. Williams, Nur Akmarina Said, Cathryn M. Gould, Erik W. Thompson, Kaylene J. Simpson. High content multiparametric functional screen for regulators of epithelial-mesenchymal transition identifies genes associated with chemoresistance. [abstract]. In: 15th International Biennial Congress of the METASTASIS RESEARCH SOCIETY; 2014 June 28 July 1; Heidelberg, Germany; CLINICAL & EXPERIMENTAL METASTASIS 2015; 32 (3):246; Abstract nr 162.
  3. Elizabeth D. Williams, Nur Akmarina Said, Cathryn M. Gould, Erik W. Thompson, Kaylene J. Simpson. High content multiparametric functional screen for regulators of epithelial-mesenchymal transition identifies genes associated with chemoresistance. [abstract]. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr 4282. doi:10.1158/1538-7445.AM2014-4282
  4. Nur Akmarina B.M. Said, Gould Cathryn M., Lackovic Kurt, Simpson Kaylene J., Williams Elizabeth D. 2014. Whole-genome multiparametric screening to identify modulators of epithelial-to-mesenchymal transition. ASSAY and Drug Development Technologies. 12(7): 385-394.
  5. Nur Akmarina B. M. Said, Simpson, K.J. & Williams, E.D. 2013. Strategies and Challenges for Systematically Mapping Biologically Significant Molecular Pathways Regulating Carcinoma Epithelial- Mesenchymal Transition. Cells Tissues Organs 197: 424- 434
  6. Nur Akmarina B.M. Said, Williams E.D. 2011. Growth factors in induction of epithelial-mesenchymal transition and metastasis. Cells Tissues Organs 193: 85-97.
  7. Emma C. Barnes, Said, N.A., Williams, E.D., Hooper, J.N.A. & Davis, R.A. 2010. Ecionines A and B, two new cytotoxic pyridoacridine alkaloids from the Australian marine sponge, Ecionemia geodides. Tetrahedron 66: 283 287
  8. Nur Akmarina B.M. Said, Williams E.D. 2009. Remodelling the malignant phenotype: impact of EMT. Drug Discovery Today: Disease Models 6: 21-5.

RESEARCH PROJECT

National
  1. 2020 - 2023, RU Geran - Fakulti Program
    Clinical And Molecular Investigation On The Role Of Cholesterol In Improving Drug Response In Bladder Cancer ( Co-Researcher)
  2. 2019 - 2022, Others MOHE - Top 100 (IIRG)-HWB
    Characterization Of Farnesyl Diphosphate Farnesyltransferase 1 (fdft1) Expression In Cisplatin -treated Muscle -invasive Bladder Cancer ( Co-Researcher)
  3. 2019 - 2022, Others MOHE - Top 100 (IIRG)-HWB
    Spectroscopic Diagnosis And Molecular Characterisation Of Cisplatin Resistance Regulated By Fdft1 In Bladder Cancer Using Raman And Saxs ( Co-Researcher)
  4. 2019 - 2022, Others MOHE - Top 100 (IIRG)-HWB
    Mirna Regulation Of Fdft1 In Mediating Chemoresistance In Bladder Cancer ( Principal Investigator(PI))
  5. 2021 - 2022, RU Geran - ADEC
    Keeping The Flame Alive: Delivering The Best Pharmacology Foundation To Ensure Effective Application And Continuous Motivation Throughout Pharmacy Program In The Online Learning Norm. ( Principal Investigator(PI))
  6. 2017 - 2021, Grand Challenge - SBS (Equitable Society)
    Impact Of Palm Oil Consumption On Cardiovascular Health ( Co-Researcher)
  7. 2016 - 2020, Fundamental Research Grant Scheme (FRGS)
    The Role Of Fibroblast On Microrna Regulation Of Epithelial To Mesenchymal Transition-mediated Cisplatin Resistance In Bladder Cancer ( Principal Investigator(PI))
  8. 2017 - 2020, UM Grant - Frontier Research Grant
    Regulation Of Cell Motility By Cancer-associated Fibroblasts To Induce Stemness Traits In Endometrial Cancer ( Co-Researcher)
  9. 2017 - 2019, Bantuan Kecil Penyelidikan (BKP)
    Metabolic role of fatty acid transporters (CD36) in endometrial cancer progression among obese and diabetic patients ( Co-Researcher)
  10. 2015 - 2017, Geran Penyelidikan Universiti Malaya (UMRG) - AFR (Frontier Science)
    Investigating the role of miR-548m in epithelial-mesenchymal transition of cancer metastasis ( Principal Investigator(PI))

CONSULTANCY PROJECT

  • Health Supplement Product Write Up for Duopharma Innovation Sdn Bhd, DUOPHARMA INNOVATION SDN. BHD., Project Leader/Lead Consultant
    26 Oct 2023 - 10 Nov 2023 (National)

PAPER PRESENTED

POSTER PRESENTER
  1. Integration of histopathological, structural and molecular approaches as predictive tool for cholesterol-mediated chemosensitivity in muscle-invasive bladder cancer, 5th International Conference on Molecular Diagnostics & Biomarker Discovery (MDBD 2020), Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia  (International) (17 Nov 2020 - 18 Nov 2020)
  2. The role of fibroblasts on microRNA regulation of epithelial to mesenchymal transition- mediated cisplatin resistance in bladder cancer, 2nd TYAN-YSN International Thematic Workshop Certificate, TYAN-YSN  (International) (30 Oct 2018 - 01 Nov 2018)
  3. High content multiparametric functional screen for regulators of epithelial-mesenchymal transition identifies genes associated with chemoresistance, 2nd International Conference for Molecular Biology and Biotechnology, Malaysian Society for Molecular Biology and Biotechnology  (International) (01 Nov 2017 - 02 Nov 2017)
  4. Development of a high content screening assay to screen for modulators of epithelial-mesenchymal transition in cancer metastasis, 5th International Epithelial-Mesenchymal Transition Meeting, TEMTIA (International) (10 Oct 2011 - 13 Oct 2011)
  5. Development of an Epithelial Reporter System for High Content Screening, The Australian Health & Medical Research Congress (AHMRC) , The Australian Health & Medical Research Congress (International) (30 Jun 2010 - 30 Jun 2010)
  6. Development of a high content screening assay to screen for modulators of EMT in cancer metastasis, 22nd Lorne Cancer Conference , Lorne Cancer (International) (12 Feb 2010 - 14 Feb 2010)
PRESENTER
  1. Development of a high content screening assay to screen for modulators of epithelial-mesenchymal transition in cancer metastasis, 2nd RNAi Australia and 5th Australian High-Content Screening meeting, RNAi Australia (National) (14 Jul 2011 - 15 Jul 2011)
OTHERS
  1. Masterclass in Systemic Cancer Therapy (participant), Masterclass in Systemic Cancer Therapy , Malaysian Oncological Society (University) (09 Mar 2018 - 10 Mar 2018)
  2. Genetic, epigenetic and metabolic drivers, Malaysia Obesity Workshop, UK Academy of Medical Sciences (International) (02 Oct 2017 - 03 Oct 2017)

SUPERVISION

Postgraduate Student
PhD/ Doctoral
  1. (2018) The role of fibroblast on microRNA regulation of epithelial to mesenchymal transition-mediated cisplatin resistance in bladder cancer, YOGAAMBIKAI A/P PARAMANANTHAM
  2. (2017) Cellular and Molecular Signatures of Cancer Stem-Like Cells in Hepatocellular Carcinoma., AIN ZUBAIDAH AYOB
Master
  1. (2020) The Role of Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) in Mediating Chemosensitivity in Muscle-Invasive Bladder Cancer, Nurul Amniyyah Azhar
  2. (2017) Investigating the Role of miR-548m in Epithelial-mesenchymal Transition of Cancer Metastasis, WAN MUHAMMAD FARHAN SYAFIQ BIN WAN MOHD NOR