Curriculum Vitae

DR. NUR KUSAIRA BINTI KHAIRUL IKRAM

Senior Lecturer
  • Institute of Biological Sciences
    Faculty of Science
  • nkusaira
  • 03-79674366

BIOGRAPHY

Dr. Nur Kusaira is a dedicated plant biotechnology researcher with a deep passion for unlocking the therapeutic and nutritional potential of plant natural products. Her academic journey began with a Bachelor's degree in Plant Resource Science and Management from Universiti Malaysia Sarawak (UNIMAS) in 2008, majoring in Plant Systematics. She was awarded the Best Undergraduate Thesis that year.

She went on to earn a Master's in Healthcare Biotechnology from Universiti Sains Malaysia (USM), where she focused on in silico screening of phytocompounds against H5N1 and H1N1 influenza viruses under the supervision of Prof. Dr. Habibah Abd Wahab. In 2012, she undertook a research attachment at UC San Diego, where she conducted molecular dynamics simulations of plant-based inhibitors targeting the NS2B/NS3 protein of Dengue virus type 2 (DENV-2).

Her career then led her to Malaysian Institute of Pharmaceuticals and Nutraceuticals (IPharm), where she managed the USM-RIKEN natural product discovery grant, working on the development of a comprehensive library of Malaysian plant extracts intended for diverse bioactivity screenings, laying the groundwork for systematic exploration of Malaysia’s phytochemical biodiversity.

Though initially set to pursue her PhD at USM, Dr. Nur Kusaira was awarded an international PhD scholarship by Universiti Malaya and joined the University of Copenhagen, Denmark, under Prof. Dr Henrik Toft Simonsen. Her PhD work made headlines in plant synthetic biology, she pioneered the use of Physcomitrella patens for stable in vivo assembly of biosynthetic gene clusters, achieving the first stable plant-based production of artemisinin, a vital antimalarial drug, marking a breakthrough in sustainable pharmaceutical production.

Her research continues at the intersection of plant science, biotechnology, and health. She focuses on:

  • Functional Food Innovation: Developing plant-based bioactives with nutraceutical properties for preventive health and wellness.
  • Drug Discovery: Leveraging computational tools to identify potent, selective plant-based inhibitors targeting cancer, viral and microbial proteins.
  • Plant Synthetic Biology: Exploring plant platforms like moss and medicinal species for scalable biosynthesis of valuable therapeutic molecules.

Dr. Nur Kusaira’s work reflects a commitment to sustainability, global health, and innovation paving the way for plant-derived therapeutics that are effective, affordable, and accessible worldwide.

AREAS OF EXPERTISE

  • CHEMICAL MODIFICATION
    Life Sciences, Biological Sciences, Biochemistry
  • NATURAL PRODUCT RESEARCH
    Medical And Health Sciences, Pharmacy, Biopharmacy And Bioproducts
  • FUNCTIONAL FOOD BIOTECHNOLOGY
    Applied Science And Technology, Biotechnology, Food Biotechnology
  • SYNTHETIC METABOLIC ENGINEERING
    Applied Science And Technology, Biotechnology, Synthetic Biotechnology
  • CIRCULAR ECONOMY
    Environment Sustainability, Sustainable Consumption And Production (scp)
  • SUSTAINABLE, SAFE AND NUTRITIOUS FOOD
    Environment Sustainability, Sustainable Consumption And Production (scp)
  • HIGH VALUE COMMODITIES
    Economic Empowerment, Economic Growth
  • SMART AND HIGH VALUE AGRICULTURE
    Economic Empowerment, Economic Growth
  • OTHER KNOWLEDGE NETWORKS AND ECOSYSTEM N.E.C
    Advancement Of Knowledge And Learning, Knowledge Networks And Ecosystem

ACADEMIC QUALIFICATION

  • PhD (Biotechnology) (2017), (Biotechnology)
    University of Copenhagen
  • MSc (Healthcare Biotechnology) (2012), (Healthcare Biotechnology)
    Universiti Sains Malaysia (usm)
  • BSc (Hons) (Plant Resource Science and Management) (2008), (Plant Resource Science and Management)
    Universiti Malaysia Sarawak (unimas)

ADMINISTRATIVE DUTIES

  • Supervisor
    10 Sep 2024 - 31 Aug 2027 (Institute of Biological Sciences, Faculty of Science)
  • Task Force Leader
    04 Jun 2025 - 31 Mar 2026 (University Malaya)
  • Task Force Member
    20 Sep 2023 - 30 Sep 2025 (Institute of Biological Sciences, Faculty of Science)
  • Programme Coordinator
    06 Sep 2023 - 29 Sep 2025 (Institute of Biological Sciences, Faculty of Science)
  • Task Force Member
    30 Sep 2024 - 29 Aug 2025 (Institute of Biological Sciences, Faculty of Science)
  • SESI LIBAT URUS PEMBANGUNAN GARIS PANDUAN BIOETIKA DI MALAYSIA
    18 Jun 2025 - 18 Jun 2025 (National)
  • Task Force Member
    28 Apr 2025 - 30 May 2025 (University Malaya)
  • Task Force Member
    23 Sep 2024 - 30 Sep 2024 (Institute of Biological Sciences, Faculty of Science)
  • Task Force Leader
    09 Jul 2024 - 31 Jul 2024 (Institute of Biological Sciences, Faculty of Science)
  • Task Force Member
    15 Mar 2024 - 22 Mar 2024 (Faculty)
  • Task Force Member
    22 Feb 2024 - 29 Feb 2024 (Institute of Biological Sciences, Faculty of Science)
  • Course Coordinator
    01 Feb 2022 - 28 Feb 2023 (Department)
  • Task Force Member
    05 Dec 2022 - 05 Dec 2022 (Institute of Biological Sciences, Faculty of Science)
  • Task Force Member
    01 Jun 2022 - 28 Oct 2022 (Institute of Biological Sciences, Faculty of Science)
  • Panel Penasihat Akademik Sesi 2020/2021
    12 Oct 2020 - 30 Sep 2022 (Institute of Biological Sciences, Faculty of Science)
  • AJK Promosi Program Ijazah Tinggi Fakulti Sains
    01 Feb 2021 - 30 Jun 2022 (Institute of Biological Sciences, Faculty of Science)
  • Task Force Member
    14 Jun 2022 - 17 Jun 2022 (Institute of Biological Sciences, Faculty of Science)
  • Coordinator
    12 Oct 2020 - 30 Sep 2021 (Institute of Biological Sciences, Faculty of Science)
  • Ahli Jawatankuasa Penilai Luar Program dan Semakan Kurikulim (kajian pasaran Industri) Program Bioteknoloigi
    30 Jan 2019 - 31 Jan 2021 (Institute of Biological Sciences, Faculty of Science)
  • Chairman
    10 Dec 2020 - 10 Dec 2020 (Institute of Biological Sciences, Faculty of Science)
  • Coordinator
    29 Nov 2018 - 29 Nov 2020 (Institute of Biological Sciences, Faculty of Science)
  • Panel Penasihat Akademik
    12 Sep 2018 - 30 Sep 2020 (Institute of Biological Sciences, Faculty of Science)
  • Chairman
    09 Jun 2020 - 09 Jun 2020 (Institute of Biological Sciences, Faculty of Science)
  • Chairman
    09 Jun 2020 - 09 Jun 2020 (Institute of Biological Sciences, Faculty of Science)
  • Chairman
    14 May 2020 - 14 May 2020 (Institute of Biological Sciences, Faculty of Science)
  • Ahli Jawatankuasa Program Khidmat Masyarakat Institut Sains Biologi, Fakulti Sains (merancang dan mengelola aktiviti kemasyarakatan di dalam dan di luar kampus)
    26 Apr 2018 - 27 Apr 2020 (Institute of Biological Sciences, Faculty of Science)

MEMBERSHIPS

  • EUROPEAN FEDERATION OF BIOTECHNOLOGY, MEMBER
    Since 2019 (International)
  • ASIAN FEDERATION OF BIOTECHNOLOGY, MEMBER
    Since 2019 (International)
  • MALAYSIAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY), MEMBER
    2019 to present (National)
  • MALAYSIAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY), MEMBER
    2019 to 2024 (National)
  • CENTRE FOR RESEARCH IN BIOTECHNOLOGY FOR AGRICULTURE (CEBAR), MEMBER
    2021 to 2023 (University)
  • MALAYSIAN SOCIETY FOR MOLECULAR BIOLOGY AND BIOTECHNOLOGY, MEMBER
    2019 to 2023 (National)

AWARD AND STEWARDSHIP

  • Silver Medal- Universiti Malaya Undergraduate Ideas Festival 2025 (ug Ifest 2025)
    2025, UNIVERSITI MALAYA,  (University)
  • Gold Medal- Borneo International Innovation Creativity
    2025, MALAYSIA YOUNG SCIENTIST ORGANIZATION,  (International)
  • Gold Medal- International Virtual Competition of Creative & Innovative Idea (ivccii)
    2025, Mediate Nexus and Nurture a Fast ???Network,  (International)
  • Certificate of Excellent Service
    2024, Universiti Malaya
  • Certificate of Award & Plaque: Invited Speaker and Panel of Jury At The Third International Seminar On Pharmaceutical Sciences and Technology
    2018, Universitas Padjadjaran, Jatinangor Indonesia,  (International)
  • Anugerah Cemerlang Universiti Malaya (acum)
    2018, Universiti Malaya,  (University)
  • Research and Innovation (gold Medal) Iidex UiTM 2018
    2018, Universiti Teknologi Mara (UITM), Shah Alam,  (National)
  • Research and Innovation (gold Medal) Epic UiTM 2018 (first Author)
    2018, Universiti Teknologi Mara Kuala Terengganu,  (National)

PUBLICATIONS

Article in Journal
WoS
  1. Arisanti, Cokorda Istri Sri; Musfiroh, Ida; Wirasuta, I. Made Agus Gelgel; Ikram, Nur Kusaira Khairul; Muchtaridi, Muchtaridi (2025). Optimization of Ethanol Concentration and Wetting Time for Industrial-Scale Production of Ipomoea batatas L. Leaf Extract, APPLIED SCIENCES-BASEL. 15(8). doi:10.3390/app15084299
  2. Caliskan, Imene Tatar; Ametefe, George Dzorgbenya; Caliskan, Aziz; Lau, Su-Ee; Liew, Yvonne Jing Mei; Ikram, Nur Kusaira Khairul; Tan, Boon Chin (2025). Unraveling the Functional Diversity of MYB Transcription Factors in Plants: A Systematic Review of Recent Advances, PHYTON-INTERNATIONAL JOURNAL OF EXPERIMENTAL BOTANY. . doi:10.32604/phyton.2025.067225
  3. Hasyim, Dadang Muhammad; Musfiroh, Ida; Hendra, Rudi; Fakih, Taufik Muhammad; Ikram, Nur Kusaira Khairul; Muchtaridi, Muchtaridi (2025). In Silico Approaches for the Discovery of Novel Pyrazoline Benzenesulfonamide Derivatives as Anti-Breast Cancer Agents Against Estrogen Receptor Alpha (ER ), APPLIED SCIENCES-BASEL. 15(15). doi:10.3390/app15158444
  4. Muchtaridi, Muchtaridi; Lestyawan, Samuel; Fakhirah, Maitsa Alya; Rusdin, Agus; Salsabila, Shela; Megantara, Sandra; Subarnas, Anas; Ikram, Nur Kusaira Khairul (2025). Therapeutic Potential of Erythrina Genus: Bioactive Phytoconstituents with Potent Antiviral and Antimicrobial Activities, PLANTS-BASEL. 14(19). doi:10.3390/plants14193053
  5. Muchtaridi, Muchtaridi; Prasetiawati, Riska; Alawiah, Siti Ajah; Salsabila, Shela; Fakih, Taufik Muhammad; Nuwarda, Rina Fajri; Ikram, Nur Kusaira Khairul (2025). Revitalizing Recovery: Unveiling the Potential of Apigenin and Related Flavonoids in Long COVID-19 Therapy Through Molecular Dynamics Simulation, APPLIED SCIENCES-BASEL. 15(3). doi:10.3390/app15031493
  6. Salsabila, Shela; Khairinisa, Miski Aghnia; Wathoni, Nasrul; Sufiawati, Irna; Fuad, Wan Ezumi Mohd; Ikram, Nur Kusaira Khairul; Muchtaridi, Muchtaridi (2025). In vivo toxicity of chitosan-based nanoparticles: a systematic review, ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY. 53(1), 1-15. doi:10.1080/21691401.2025.2462328
  7. Aborziza, Mohamed; Amalia, Riezki; Zuhrotun, Ade; Ikram, Nur Kusaira Khairul; Novitasari, Dhania; Muchtaridi, Muchtaridi (2024). Coffee Bean and Its Chemical Constituent Caffeine and Chlorogenic Acid as Promising Chemoprevention Agents: Updated Biological Studies against Cancer Cells, MOLECULES. 29(14). doi:10.3390/molecules29143302
  8. Arifian, Hanggara; Maharani, Rani; Megantara, Sandra; Ikram, Nur Kusaira Khairul; Muchtaridi, Muchtaridi (2024). Glycine-Conjugated -Mangostins as Potential Estrogen Receptor Alpha (ER ) Antagonists through Pharmacophore Modeling, Docking Analysis, and Molecular Dynamics Simulations, APPLIED SCIENCES-BASEL. 14(13). doi:10.3390/app14135549
  9. Musfiroh, Ida; Ifaya, Mus; Sahidin, I.; Herawati, Dewi M. D.; Tjitraresmi, Ami; Abdurrahman, Syawal; Muchtaridi, Muchtaridi; Khairul Ikram, Nur Kusaira (2024). Isolation of phenolic compound from Lawsonia inermis and its prediction as anti-diabetic agent using molecular docking and molecular dynamic simulation, JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS. . doi:10.1080/07391102.2023.2262595
  10. Setyawati, Luthfi Utami; Parlan, Fateen Izzah Haziqah Binti; Ikram, Nur Kusaira Khairul; Yusuf, Muhammad; Muchtaridi, Muchtaridi (2024). Molecular Dynamic Simulation and 3d-pharmacophore Modeling of Alpha Mangostin and Its Derivatives against Estrogen Alpha Receptor, LETTERS IN DRUG DESIGN & DISCOVERY. 21(6), 1103-1119. doi:10.2174/1570180820666230220122600
  11. Zakariya, Ali Muhammad; Saiman, Mohd Zuwairi; Simonsen, Henrik Toft; Ikram, Nur Kusaira Khairul (2024). Current state, strategies, and perspectives in enhancing artemisinin production, PHYTOCHEMISTRY REVIEWS. . doi:10.1007/s11101-023-09897-6
  12. Musfiroh, Ida; Kartasasmita, Rahmana E.; Ibrahim, Slamet; Muchtaridi, Muchtaridi; Hidayat, Syahrul; Ikram, Nur Kusaira Khairul (2023). Stability Analysis of the Asiatic Acid-COX-2 Complex Using 100 ns Molecular Dynamic Simulations and Its Selectivity against COX-2 as a Potential Anti-Inflammatory Candidate, MOLECULES. 28(9). doi:10.3390/molecules28093762
  13. Mustapa, Mohammad Adam; Guswenrivo, Ikhsan; Zurohtun, Ade; Ikram, Nur Kusaira Khairul; Muchtaridi, Muchtaridi (2023). Analysis of Essential Oils Components from Aromatic Plants Using Headspace Repellent Method against Aedes aegypti Mosquitoes, MOLECULES. 28(11). doi:10.3390/molecules28114269
  14. Nurhidayah, Wiwit; Widyasari, Eva Maria; Daruwati, Isti; Mahendra, Isa; Subroto, Toto; Khairul Ikram, Nur Kusaira; Muchtaridi, Muchtaridi (2023). Radiosynthesis, Stability, Lipophilicity, and Cellular Uptake Evaluations of [I-131]Iodine-alpha-Mangostin for Breast Cancer Diagnosis and Therapy, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 24(10). doi:10.3390/ijms24108678
  15. Setyawati, Luthfi Utami; Nurhidayah, Wiwit; Ikram, Nur Kusaira Khairul; Fuad, Wan Ezumi Mohd; Muchtaridi, Muchtaridi (2023). General toxicity studies of alpha mangostin from Garcinia mangostana: A systematic review, HELIYON. 9(5). doi:10.1016/j.heliyon.2023.e16045
  16. Dewi, Citra; Fristiohady, Adryan; Amalia, Riezki; Khairul Ikram, Nur Kusaira; Ibrahim, Sugeng; Muchtaridi, Muchtaridi (2022). Signaling Pathways and Natural Compounds in Triple-Negative Breast Cancer Cell Line, MOLECULES. 27(12). doi:10.3390/molecules27123661
  17. Khutami, Chindiana; Sumiwi, Sri Adi; Khairul Ikram, Nur Kusaira; Muchtaridi, Muchtaridi (2022). The Effects of Antioxidants from Natural Products on Obesity, Dyslipidemia, Diabetes and Their Molecular Signaling Mechanism, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 23(4). doi:10.3390/ijms23042056
  18. Muchtaridi, Muchtaridi; Abdullah, Derif A.; Suhandi, Cecep; Sumiwi, Sri A.; Ikram, Nur Kusaira Khairul (2022). Anti-Inflammatory Activity of Alpinia malaccensis (Burm. f.) Roscoe and Kaempferia galanga L. Rhizome Essential Oil Gel Formulations by Carrageenan Induction Method, SAINS MALAYSIANA. 51(5), 1411-1424. doi:10.17576/jsm-2022-5105-12
  19. Mustapa, Mohammad Adam; Guswenrivo, Ikhsan; Zuhrotun, Ade; Ikram, Nur Kusaira Khairul; Muchtaridi, Muchtaridi (2022). Anti-Breast Cancer Activity of Essential Oil: A Systematic Review, APPLIED SCIENCES-BASEL. 12(24). doi:10.3390/app122412738
  20. Muchtaridi, M., Lestari, D., Ikram, N. K. K., Gazzali, A. M., Hariono, M., & Wahab, H. A. (2021). Decaffeination and Neuraminidase Inhibitory Activity of Arabica Green Coffee (Coffea arabica) Beans: Chlorogenic Acid as a Potential Bioactive Compound. Molecules, 26(11), 11. doi: 10.3390/molecules26113402
  21. Muchtaridi, M., Fauzi, M., Ikram, N. K. K., Gazzali, A. M., & Wahab, H. A. (2020). Natural Flavonoids as Potential Angiotensin-Converting Enzyme 2 Inhibitors for Anti-SARS-CoV-2. Molecules, 25(17), 20. doi: 10.3390/molecules25173980
  22. Sahruzaini, Nurul Amylia; Rejab, Nur Ardiyana; Harikrishna, Jennifer Ann; Khairul Ikram, Nur Kusaira; Ismail, Ismanizan; Kugan, Hazel Marie; Cheng, Acga (2020). Pulse Crop Genetics for a Sustainable Future: Where We Are Now and Where We Should Be Heading, FRONTIERS IN PLANT SCIENCE. 11. doi:10.3389/fpls.2020.00531
  23. Ikram, Nur Kusaira Khairul; Kashkooli, Arman Beyraghdar; Peramuna, Anantha; van der Krol, Alexander R.; Bouwmeester, Harro; Simonsen, Henrik Toft (2019). Insights into Heterologous Biosynthesis of Arteannuin B and Artemisinin in Physcomitrella patens, MOLECULES. 24(21). doi:10.3390/molecules24213822
  24. Ikram, Nur K. B. K.; Simonsen, Henrik T. (2017). A Review of Biotechnological Artemisinin Production in Plants, FRONTIERS IN PLANT SCIENCE. 8. doi:10.3389/fpls.2017.01966
  25. Ikram, Nur Kusaira Binti Khairul; Kashkooli, Arman Beyraghdar; Peramuna, Anantha Vithakshana; van der Krol, Alexander R.; Bouwmeester, Harro; Simonsen, Henrik Toft (2017). Stable Production of the Antimalarial Drug Artemisinin in the Moss Physcomitrella patens, FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY. 5. doi:10.3389/fbioe.2017.00047
Scopus
  1. Muchtaridi M., Prasetiawati R., Alawiah S.A., Salsabila S., Fakih T.M., Nuwarda R.F., Ikram N.K.K. (2025). Revitalizing Recovery: Unveiling the Potential of Apigenin and Related Flavonoids in Long COVID-19 Therapy Through Molecular Dynamics Simulation, Applied Sciences (Switzerland). 15(3). doi:10.3390/app15031493
  2. Musfiroh I., Maritha V., Harlina P.W., Muchtaridi M., Bakar N.K.A., Rohman A., Dachriyanus D., Ikram N.K.K., Windarsih A. (2025). Chemometrics applications in omics studies (Metabolomics, Lipidomics, and Proteomics) for halal authentication in food and pharmaceutical products, Applied Food Research. 5(1). doi:10.1016/j.afres.2025.100770
  3. Prasetiawati R., Febrianti E.N., Hamdani S., Ikram N.K.K., Fakih T.M., Novitasari D., Muchtaridi M. (2025). Alpha-mangostin from Garcinia mangostana L.: A potential Nrf2 inhibitor for long COVID-19 explored through molecular dynamics, Journal of Pharmacy and Pharmacognosy Research. 13(2), 381-392. doi:10.56499/jppres24.2066_13.2.381
  4. Salsabila S., Khairinisa M.A., Wathoni N., Sufiawati I., Mohd Fuad W.E., Khairul Ikram N.K., Muchtaridi M. (2025). In vivo toxicity of chitosan-based nanoparticles: a systematic review, Artificial Cells, Nanomedicine and Biotechnology. 53(1), 1-15. doi:10.1080/21691401.2025.2462328
  5. Aborziza M., Amalia R., Zuhrotun A., Ikram N.K.K., Novitasari D., Muchtaridi M. (2024). Coffee Bean and Its Chemical Constituent Caffeine and Chlorogenic Acid as Promising Chemoprevention Agents: Updated Biological Studies against Cancer Cells, Molecules. 29(14). doi:10.3390/molecules29143302
  6. Arifian H., Maharani R., Megantara S., Ikram N.K.K., Muchtaridi M. (2024). Glycine-Conjugated -Mangostins as Potential Estrogen Receptor Alpha (ER ) Antagonists through Pharmacophore Modeling, Docking Analysis, and Molecular Dynamics Simulations, Applied Sciences (Switzerland). 14(13). doi:10.3390/app14135549
  7. Wahyuni D.K., Indriati D.T., Ilham M., Murtadlo A.A.A., Purnobasuki H., Junairiah, Purnama P.R., Ikram N.K.K., Samian M.Z., Subramaniam S. (2024). Morpho-anatomical characterization and DNA barcoding of Artemesia vulgaris L., Brazilian Journal of Biology. 84. doi:10.1590/1519-6984.278393
  8. Zakariya A.M., Saiman M.Z., Simonsen H.T., Ikram N.K.K. (2024). Current state, strategies, and perspectives in enhancing artemisinin production, Phytochemistry Reviews. . doi:10.1007/s11101-023-09897-6
  9. Lestari D., Sari R.P., Musfiroh I., Megantara S., Praceka M.S., Ikram N.K.K., Muchtaridi (2023). INTERACTIONS OF XANTHONE COMPOUNDS FROM THE MANGOSTEEN (GARCINIA MANGOSTANA L) PERICARPS AGAINST INOS, COX-1, AND COX-2 ENZYME RECEPTORS AS ANTI-INFLAMMATORY, International Journal of Applied Pharmaceutics. 15(1), 186-194. doi:10.22159/ijap.2023v15i1.45861
  10. Muchtaridi, Darmawan M., Elizabeth M., Nurzanah D., Margaretha P., Elaine A.A., Neli, Puspitadewi N., Setyawati L.U., Ikram N.K.K. (2023). INTERACTIONS OF ORTHOSIPHON STAMINEUS COMPOUNDS AGAINST COX-2 AS AN ANTIINFLAMMATORY USING IN SILICO METHODS AND TOXICITY PREDICTION, International Journal of Applied Pharmaceutics. 15(6), 288-296. doi:10.22159/ijap.2023v15i6.48663
  11. Musfiroh I., Kartasasmita R.E., Ibrahim S., Muchtaridi M., Hidayat S., Ikram N.K.K. (2023). Stability Analysis of the Asiatic Acid-COX-2 Complex Using 100 ns Molecular Dynamic Simulations and Its Selectivity against COX-2 as a Potential Anti-Inflammatory Candidate, Molecules. 28(9). doi:10.3390/molecules28093762
  12. Musfiroh I., Sigalingging O.S., Suhandi C., Ikram N.K.K., Megantara S., Muchtaridi M. (2023). IN SILICO STUDY OF SOME FLAVONOID COMPOUNDS AGAINST ACE-2 RECEPTORS AS ANTI-COVID-19, International Journal of Applied Pharmaceutics. 15(4), 225-230. doi:10.22159/ijap.2023v15i4.48109
  13. Junaidin J., Lestari D., Kurniawan M.F., Khairul Ikram N.K. (2022). Ligand-based pharmacophore modeling, molecular docking, and molecular dynamic studies of HMG-CoA reductase inhibitors, Informatics in Medicine Unlocked. 32. doi:10.1016/j.imu.2022.101063
  14. Khairul Ikram E.H., Wan Mohd Nasir W.D.N., Khairul Ikram N.K. (2022). Antioxidant Activity and Total Phenolics Content of Brazilian Spinach(Alternantherasissoo)and Spinach Cultivarin Malaysia, Malaysian Journal of Medicine and Health Sciences. 18(8), 221-229. doi:10.47836/mjmhs18.8.29
  15. Khutami C., Sumiwi S.A., Khairul Ikram N.K., Muchtaridi M. (2022). The Effects of Antioxidants from Natural Products on Obesity, Dyslipidemia, Diabetes and Their Molecular Signaling Mechanism, International Journal of Molecular Sciences. 23(4). doi:10.3390/ijms23042056
  16. Balamurugan, J. P., Supramani, S., Ahmad Usuldin, S. R., Ilham, Z., Klaus, A., Khairul Ikram, N. K., . . . Wan-Mohtar, W. A. A. Q. I. (2021). Efficient biomass-endopolysaccharide production from an identified wild-Serbian Ganoderma applanatum strain BGS6Ap mycelium in a controlled submerged fermentation. Biocatalysis and Agricultural Biotechnology, 37. doi: 10.1016/j.bcab.2021.102166
  17. Ahmad Usuldin S.R., Mahmud N., Ilham Z., Khairul Ikram N.K., Ahmad R., Wan-Mohtar W.A.A.Q.I. (2020). In-depth spectral characterization of antioxidative (1,3)- -D-glucan from the mycelium of an identified tiger milk mushroom Lignosus rhinocerus strain ABI in a stirred-tank bioreactor, Biocatalysis and Agricultural Biotechnology. 23. doi:10.1016/j.bcab.2019.101455
Others
  1. Shahril Efzueni Rozali, Mahanom Jalil, Nur Kusaira Khairul Ikram, Jamilah Syafawati Yaacob, Lim Yen-Theng, Sakthivel Balakrisnan. In Vitro Germination, Callus Induction and Shoot Multiplication of Important Medicinal Plant, Christia Vespertilionis (L.F.) Bakh.F. TEST Engineering and Management. 2020, 83, 6673-6678.
  2. Usuldin, S. R. A., Mahmud, N., Ilham, Z., Ikram, N. K. K., Ahmad, R., & *Wan-Mohtar, W. A. A. Q. I. (2020). In-depth spectral characterization of antioxidative (1, 3)- -D-glucan from the mycelium of an identified tiger milk mushroom Lignosus rhinocerus strain ABI in a stirred-tank bioreactor. Biocatalysis and Agricultural Biotechnology, 23, 101455., doi: https://doi.org/10.1016/j.bcab.2019.101455
  3. King, B. C., Vavitsas, K., Ikram, N. K. B. K., Schr der, J., Scharff, L. B., Bassard, J.- ., . . . Simonsen, H. T. (2016). In vivo assembly of DNA-fragments in the moss, Physcomitrella patens. Scientific reports
  4. Sabovljevi , M. S., Sabovljevi , A. D., Ikram, N. K. K., Peramuna, A., Bae, H., & Simonsen, H. T. (2016). Bryophytes an emerging source for herbal remedies and chemical production. Plant Genetic Resources, 14(4), 314-327.
  5. Yaeghoobi, M., Frimayanti, N., Chee, C. F., Ikram, K. K., Najjar, B. O., Zain, S. M., . . . Rahman, N. A. (2016). QSAR, in silico docking and in vitro evaluation of chalcone derivatives as potential inhibitors for H1N1 virus neuraminidase. Medicinal Chemistry Research, 25(10), 2133-2142.
  6. Ikram, N. K. K., Durrant, J. D., Muchtaridi, M., Zalaludin, A. S., Purwitasari, N., Mohamed, N., . . . Rahman, N. A. (2015). A virtual screening approach for identifying plants with anti H5N1 neuraminidase activity. Journal of chemical information and modeling, 55(2), 308-316.
  7. Ikram, N., Zhan, X., Pan, X.-W., King, B. C., & Simonsen, H. T. (2015). Stable heterologous expression of biologically active terpenoids in green plant cells. Frontiers in plant science, 6, 129.

RESEARCH INTEREST

  • Plant metabolic engineering for the production of valuable metabolites (genetic engineering, metabolic engineering, Genetic modification, Synthetic biology, Metabolite production, Bioactive compounds, Metabolic pathways, Plant synthetic biology, Phytochemicals, Biopharmaceuticals)
  • Plant pathway elucidation (Biosynthetic pathways, Metabolic pathways, biopharmaceutical)
  • Plant natural Products, computational biochemistry (Molecular docking, virtual screening)

RESEARCH PROJECT

National
  1. 2020 - 2023, Fundamental Research Grant Scheme (FRGS)
    Bioactive Compounds Recovery and Growth Performance of Castanea sativa Mill. in different environment ( Consultant)
  2. 2020 - 2023, FRGS
    Bioactive Compounds Recovery and Growth Performance of Castanea sativa Mill. in different environment, Universiti Malaysia Sarawak (UNIMAS) ( Co-Researcher)
International
  1. 2024 - 2026, Riset Mandatory 2 Tahun 2024
    Metabolomic and transcriptomic analysis of Indonesian Sonchus arvensis L. during developmental period: Leading to scale up to metabolite production through biological engineering, Universitas Airlangga ( Co-Researcher)
  2. 2023 - 2024, SATU JOINT RESEARCH SCHEME
    Glutamine and Methyl Jasmonate for enhancing the metabolite production of Sonchus arvensis L. culture under LED treatment, Universitas Airlangga ( Co-Researcher)
  3. 2023 - 2024, KOMPETENSI DOSEN UNPAD (RKDU)
    SENYAWA AKTIF ANTIDIABETES EKSTRAK DAUN PACAR KUKU (Lawsonia inermis L.) DAN UJI MEKANISME MOLEKULERNYA, Universitas Padjadjaran ( Co-Researcher)

PAPER PRESENTED

CONFERENCE
  1. Enhancement of Saponins Production from Adventitious Roots Culture of Talinum fruticosum (L.) Juss., 12th AFOB Regional Symposium (ARS) 2020, Asian Federation of Biotechnology (AFOB) (International) (09 Feb 2020 - 11 Feb 2020)
INVITED SPEAKER
  1. INNOVATIVE PLATFORM FOR THE BIOSYNTHESIS OF PLANT-BASED NATURAL DRUG COMPOUNDS, Professional Sharing, Muhammadiyah University of Bandung (International) (05 Feb 2025 - 05 Feb 2025)
  2. Innovative Platform for the Biosynthesis f Plant-Based Natural Drug Compounds, Kuliah Pakar, Universitas Bakti Tunas Husada, Tasikmalaya Indonesia (International) (02 Feb 2025 - 02 Feb 2025)
  3. GREEN PRODUCTION OF PHARMACEUTICALS: THE CASE OF ARTEMISININ, USD Pharmacy International Webinar Series (UPIWeS) 2021, Faculty of Pharmacy, Sanata Dharma University, Yogyakarta , Indonesia (International) (18 Sep 2021 - 19 Sep 2021)
  4. A New Plant-Based Drug Production Platform, 3rd International Seminar on Pharmaceutical Science And Technology, Universitas Padjadjaran (International) (23 Oct 2018 - 24 Oct 2018)
ORAL PRESENTER
  1. In vitro germination, callus induction and shoot multiplication of important medicinal plant, Christia vespertilionis (l.f) Bakh.f., International Conference on Applied Science, Engineering, Technology and Management (ICASETEM-2019), Institute of Engineering Research and Publication (IFERP) (International) (16 Oct 2019 - 17 Oct 2019)
  2. Combining Natural Product and Information Technology to Spearhead Research in Drug Discovery., Bali International Seminar in Science and Technology , Bali, Indonesia (International) (22 Jul 2011 - 23 Jul 2011)
  3. Docking Validation Of Neuraminidase Inhibitors From Plant Natural Product. , The International Seminar and Expo on Jamu 2010 Herbal Medicine: Indigenous, Molecular Aspects and Clinical Application , Universitas Padjadjaran, Bandung Indonesia.  (International) (05 Nov 2010 - 06 Nov 2010)
  4. Structure Based Drug Design for Swine Flu Chemotherapeutics: New Neuraminidase Inhibitors from Plants Natural Compounds. , 14th International Annual Symposium on Computational Science and Engineering, Mah Fah Luang University, Chiang Rai Thailand.  (International) (23 Mar 2010 - 26 Mar 2010)
POSTER PRESENTER
  1. ArteMoss: A novel plant-based malarial drug production system , Asian Federation of Biotechnology- Malaysia Chapter International Symposium 2019, AFOB (International) (21 Oct 2019 - 23 Oct 2019)
  2. Spontaneous production of Arteannuin B in the moss Physcomitrella patens. , Plant Genomic Congress Asia, Global Engage (International) (04 Apr 2016 - 13 Apr 2016)
  3. Metabolite Engineering of The Moss Physcomitrella patens for the production of sesquiterpenoids., TERPNET Meeting 2015, University of British Columbia, Vancouver, Canada.  (International) (01 Jun 2015 - 05 Jun 2015)
  4. Virtual Screening Of Malaysian Plants For H1N1/H5N1 Neuraminidase Inhibition., Eight European Workshop in Drug Design, , Universit degli studi di Siena (International) (22 May 2011 - 28 May 2011)
OTHERS
  1. Dipping sauce from underutilized Carica papaya Linn. pulp and peel, The 3rd Project of Innovation Competition (EPIC), Universiti Teknologi Mara Terengganu (National) (22 Sep 2018 - 22 Sep 2018)

ACADEMIC/ PROF. SERVICES

Evaluation
  1. (2025) Viva Voice Calon Phd Jasdeep Kaur, University, (Internal Examiner)
  2. (2024) Penilai Proposal Defence Calon Msc: Aishah Amira Binti Hassan Scott Odierno (22060769/1 ), University, (Reviewer)
  3. (2024) Review Article in Journal, International, (Reviewer)
Contribution to external organisation
  1. (2025) Editor Member of Indonesian Journal of Pharmaceutical Science and Technology, International, (Expert Advisor)
  2. (2024) Adjunct Professor- Contribution in Research, International, (Adjunct/Visiting Professors)
Media appearance
  1. (2025) AJK Karnival Saintis Komuniti, Tanjung Karang- Pempamer/penyelaras Program Bioteknologi, National, (Host)

SUPERVISION

Postgraduate Student
PhD/ Doctoral
  1. (2025) Enhancement of flavonoid production by overexpressing and silencing MYB transcription factors in Boesenbergia rotunda, IMENE TATAR
  2. (2025) PHYTOCHEMICAL, ANTIOXIDANT, ANTIDIABETIC, AND METABOLOMIC STUDIES OF Artemisia vulgaris L., ZAKARIYA ALI MUHAMMAD
  3. (2023) ENHANCEMENT OF BIOACTIVE COMPOUNDS PRODUCTION IN THE in vitro MICROPROPAGATION AND FIELD GROWN CULTIVATION OF UNDERUTILIZED CROPS, Talinum triangulare FOR MEDICINAL PURPOSES, SHAHRIL EFZUENI BIN ROZALI
  4. (2021) FUNCTIONAL CHARACTERISATION OF MYB TRANSCRIPTION FACTOR FROM BOESENBERGIA ROTUNDA TO REGULATE THE FLAVONOID BIOSYNTHETIC PATHWAY, WILLIAM CHUNG WEI LAM
  5. (2018) ENHANCEMENT OF BIOACTIVE COMPOUNDS PRODUCTION IN THE in vitro MICROPROPAGATION AND FIELD GROWN CULTIVATION OF UNDERUTILIZED CROPS, Talinum triangulare FOR MEDICINAL PURPOSES, SHAHRIL EFZUENI BIN ROZALI
  6. (2016) Functional characterisation of MYB transcription factor from Boesenbergia rotunda to regulate the flavanoid biosynthetic pathway, William Chung Wei Lam
Master
  1. (2025) EXPRESSION AND CHARACTERIZATION OF Boesenbergia rotunda FLAVANONE 3-HYDROXYLASE (F3H) FOR OPTIMIZING FLAVONOID PRODUCTION, ALICIA NG JIA HUEY
  2. (2021) EXOPOLYSACCHARIDES PRODUCTION FROM WILD SERBIAN Ganoderma applanatum STRAIN (BGS6Ap) MYCELIUM IN A BATCH FERMENTATION, JOSHINI PILLAI A/P BALAMURUGAN
  3. (2019) ISOLATION AND IDENTIFICATION OF MALAYSIAN TIGER MILK MUSHROOM AND CHARACTERIZATION OF ITS MYCELIAL (1,3)-B-D-GLUCAN, SITI ROKHIYAH BINTI AHMAD USULDIN
  4. (2018) PRODUCTION AND BIOACTIVITY OF LIGNOSUS RHINOCERUS EXOPOLYSACCHARIDE USING SUBMERGED LIQUID FERMENTATION, SITI ROKHIYAH AHMAD USULDIN

TEACHING

Full-Time Equivalent (FTE)
  1. (2025) SIO1002 - Fundamental Techniques in Biological Sciences
  2. (2026) SIO1002 - Fundamental Techniques in Biological Sciences
  3. (2025) SIO2007 - Molecular Biology and Genetic Engineering
  4. (2025) SIO2015 - Plant Biotechnology
  5. (2025) SIO2017 - Scientific Writing
  6. (2025) SIO3026 - Sustainable Food Systems

PATENT/ IPR

  • DiPPs
    Copyright (National)