Curriculum Vitae

DR. TAN LI KUO

Senior Lecturer
  • Department of Biomedical Imaging
    Faculty of Medicine
  • lktan
  • 0379498008

AREAS OF EXPERTISE

  • CLINICAL ENGINEERING
  • MEDICAL PHYSICS

ACADEMIC QUALIFICATION

  • PhD, (Fizik & Kejuruteraan Bioperubatan)
    Universiti Malaya (UM)
  • MEng(Biomedical), (Kejuruteraan Bioperubatan)
    Monash University, Australia
  • BEng(Hons)(Mechatronics), (Kejuruteraan Robotik dan Kawalan)
    Monash University, Australia

ADMINISTRATIVE DUTIES

  • Head of Biomedical Engineering Unit, UMMC
    02 May 2008 - 31 Dec 2013 (University Malaya)
  • Subject Coordinator: Computing & Medical Informatics
    01 Jul 2004 - 31 Dec 2013 (Department of Biomedical Imaging, Faculty of Medicine)
  • Subject Coordinator: Biostatistics
    01 Jul 2004 - 31 Dec 2013 (Department of Biomedical Imaging, Faculty of Medicine)
  • Course Coordinator: Masters in Medical Physics
    01 Jul 2007 - 30 Jun 2010 (Department of Biomedical Imaging, Faculty of Medicine)

MEMBERSHIPS

  • NEUROLOGY ASIA JOURNAL (ISI-INDEXED), OTHERS
    Since 2004 (International)

AWARD AND STEWARDSHIP

  • EXCELLENCE SERVICE AWARD
    University of Malaya, 2009 (University)

PUBLICATIONS

Article in Journal
  1. Cheah, P. L., Krisnan, T., Wong, J. H. D., Rozalli, F. I., Fadzli, F., Rahmat, K., Shahrizaila, N., Tan, L. K., Nawawi, O., & Ramli, N. (2020). Microstructural Integrity of Peripheral Nerves in Charcot Marie Tooth Disease: An MRI Evaluation Study. Journal of Magnetic Resonance Imaging, n/a(n/a). https://doi.org/10.1002/jmri.27354
  2. Azlan, C. A., Wong, J. H. D., Tan, L. K., A.D. Huri, M. S. N., Ung, N. M., Pallath, V., Tan, C. P. L., Yeong, C. H., & Ng, K. H. (2020). Teaching and learning of postgraduate medical physics using Internet-based e-learning during the COVID-19 pandemic A case study from Malaysia. Physica Medica, 80, 10 16. https://doi.org/10.1016/j.ejmp.2020.10.002
  3. Chuah, S. H., Md Sari, N. A., Chew, B. T., Tan, L. K., Chiam, Y. K., Chan, B. T., Lim, E., Abdul Aziz, Y. F., & Liew, Y. M. (2020). Phenotyping of hypertensive heart disease and hypertrophic cardiomyopathy using personalized 3D modelling and cardiac cine MRI. Physica Medica, 78, 137 149. https://doi.org/10.1016/j.ejmp.2020.08.022
  4. Goh C-H, Tan LK, Lovell NH, Ng S-C, Tan MP, Lim E. Robust PPG Motion Artifact Detection Using a 1-D Convolution Neural Network. Comput Methods Programs Biomed. 2020;105596
  5. Norlisah Ramli , Su Sim Kuok , Li Kuo Tan , Yin Qing Tan , Lee Fan Tan , Khean Jin Goh , Khairul Azmi Abd Kadir, Pohchoo Seow, Sing Yau Goh . Effect of mindfulness meditation on brain-computer interface: fMRI perspective. Neurology Asia 2019; 24(4) : 343 353.
  6. Ramli N, Yap A, Muridan R, Seow P, Rahmat K, Fong CY, Tan LK, Ong LC. (2020). Microstructural abnormalities found in uncinate fasciculus and superior cerebellar tracts in children with global developmental delay: a feasibility study. Clinical radiology, 75(1), 77-e15.
  7. Ramli, N., Lim, C. H., Rajagopal, R., Tan, L. K., Seow, P., & Ariffin, H. (2020). Assessing changes in microstructural integrity of white matter tracts in children with leukaemia following exposure to chemotherapy. Pediatric Radiology, 1-7.
  8. Hamzah, N., Narayanan, V., Ramli, N., Mustapha, N. A., Mohammad Tahir, N.A., Tan, L. K., . . . Mazlan, M. (2019). Randomised controlled clinical trial of a structured cognitive rehabilitation in patients with attention deficit following mild traumatic brain injury: study protocol, BMJ Open, 9:e028711. doi:10.1136/bmjopen-2018-02871
  9. Ramli, N., Yap, A., Muridan, R., Seow, P., Rahmat, K., Fong, C. Y., Ong, L. C. (2019). Microstructural abnormalities found in uncinate fasciculus and superior cerebellar tracts in children with global developmental delay: A feasibility study. Clinical Radiology. https://doi.org/10.1016/j.crad.2019.09.134
  10. Tan, A. H., Ong, T. L., Ramli, N., Tan, L. K., Lim, J. L., Azhan, M. A., ... & Brashear, A. (2019). Alternating Hemiplegia of Childhood in a Person of Malay Ethnicity with Diffusion Tensor Imaging Abnormalities. Journal of Movement Disorders, 12(2), 132-134.
  11. Leong, C. O., Lim, E., Tan, L. K., Aziz, Y. F. A., Sridhar, G. S., Socrates, D., Liew, Y. M. (2019). Segmentation of left ventricle in late gadolinium enhanced MRI through 2D-4D registration for infarct localization in 3D patient-specific left ventricular model. Magnetic Resonance in Medicine, 81(2), 1385 1398. https://doi.org/10.1002/mrm.27486
  12. Li Kuo Tan, Robert A. McLaughlin, Einly Lim, Yang Faridah Abdul Aziz, and Yih Miin Liew. "Fully automated segmentation of the left ventricle in cine cardiac MRI using neural network regression." Journal of Magnetic Resonance Imaging (2018).
  13. MR NEUROGRAPHY OF MEDIAN NERVE USING DIFFUSION TENSOR IMAGING (DTI) AND ITS EFFICACY TO DIAGNOSE CARPAL TUNNEL SYNDROME IN MALAYSIAN POPULATION.. George J et al.Neurology Asia 2018; 23(1) : 17 25
  14. Tan, L. K., Liew, Y. M., Lim, E., Abdul Aziz, Y. F., Chee, K. H., & McLaughlin, R. A. (2018). Automatic localization of the left ventricular blood pool centroid in short axis cardiac cine MR images. Medical & Biological Engineering & Computing, 56(6), 1053 1062. https://doi.org/10.1007/s11517-017-1750-7
  15. Veeramuthu, V., Seow, P., Narayanan, V., Wong, J. H. D., Tan, L. K., Hernowo, A. T., & Ramli, N. (2018). Neurometabolites Alteration in the Acute Phase of Mild Traumatic Brain Injury (mTBI): An In Vivo Proton Magnetic Resonance Spectroscopy (1H-MRS) Study. Academic Radiology. doi: https://doi.org/10.1016/j.acra.2018.01.005
  16. Li Kuo Tan , Yih Miin Liew , Einly Lim , Robert A. McLaughlin. (2017) Convolutional neural network regression for short-axis left ventricle segmentation in cardiac cine MR sequences. Medical Image Analysis. 39:78-86
  17. Wong, Y. Q., Tan, L. K., Seow, P., Tan, M. P., Kadir, K. A. A., Vijayananthan, A., & Ramli, N. (2017). Microstructural integrity of white matter tracts amongst older fallers: A DTI study. PLoS one, 12(6), e0179895.
  18. Yan Ling Yong, Li Kuo Tan, Robert A. McLaughlin, Kok Han Chee, Yih Miin Liew, "Linear-regression convolutional neural network for fully automated coronary lumen segmentation in intravascular optical coherence tomography," Journal of Biomedical Optics 22(12), 126005 (2017), doi: 10.1117/1.JBO.22.12.126005.
  19. Norlisah Ramli, Azua Mohd Khairy, Pohchoo Seow, Li Kuo Tan, Jeannie Hsiu Ding Wong, Dharmendra Ganesan, Kartini Rahmat. Novel application of chemical shift gradient echo in- and opposed-phase sequences in 3 T MRI for the detection of H-MRS visible lipids and grading of glioma. Eur Radiol DOI 10.1007/s00330-015-4045-0
  20. Sidek, S., Ramli, N., Rahmat, K., Ramli, N. M., Abdulrahman, F., & Kuo, T. L. (2016). In vivo proton magnetic resonance spectroscopy (1H-MRS) evaluation of the metabolite concentration of optic radiation in primary open angle glaucoma. European Radiology, 26(12), 4404 4412. https://doi.org/10.1007/s00330-016-4279-5
  21. Veeramuthu, V., Hariri, F., Narayanan, V., Kuo, T. L., Ramli, N., & Ganesan, D. (2016). Microstructural Change and Cognitive Alteration in Maxillofacial Trauma and Mild Traumatic Brain Injury: A Diffusion Tensor Imaging Study. Journal of Oral and Maxillofacial Surgery.
  22. Veeramuthu, V., Narayanan, V., Kuo, T. L., Delano-Wood, L., Chinna, K., Bondi, M. W., ... & Ramli, N. (2015). Diffusion tensor imaging parameters in mild traumatic brain injury and its correlation with early neuropsychological impairment: a longitudinal study. Journal of neurotrauma, 32(19), 1497-1509.
  23. Yih Miin Liew, Robert A. McLaughlin, Bee Ting Chan, Yang Faridah Abdul Aziz, Kok Han Chee, Ngie Min Ung, Li Kuo Tan, Khin Wee Lai, Siew-Cheok Ng, Einly Lim. Motion corrected LV quantification based on 3D modelling for improved functional assessment in cardiac MRI. 2015. Phys. Med. Biol. 60:2715-33.
  24. S. Sidek, N. Ramli, K. Rahmat, N.M. Ramli, F. Abdulrahman, L.K. Tan. Glaucoma severity affects diffusion tensor imaging (DTI) parameters of the optic nerve and optic radiation. European Journal of Radiology, Volume 83, Issue 8, August 2014, Pages 1437-1441
  25. Nair SR, Tan LK, Mohd Ramli N, Lim SY, Rahmat K, Mohd Nor H. A decision tree for differentiating multiple system atrophy from Parkinson's disease using 3-T MR imaging. European Radiology 2013;23(6):1459-1466. (IF 4.34 in 2013).
  26. Suppiah S, Rahmat K, , Mohd-Shah MN, Ahmad A, Aziz YFA , Vijayananthan A, Tan LK , Wui AL, Yip CH. Improved diagnostic accuracy in differentiating malignant and benign lesions using single-voxel proton MR spectroscopy of the breast at 3T MRI. Clin Radiol 2013 :68 ( 9) e502 e510
  27. KB Loh, Ramli N, LK Tan, M Roziah, Rahmat K, Ariffin H. Quantification of diffusion tensor imaging in normal white matter maturation of early childhood using an automated processing pipeline. EUROPEAN RADIOLOGY Volume: 22 Issue: 7 Pages: 1413-1426 Mar 22.[Epub print ] (IF 4.34 Q1)
  28. Yik Hoay Mah, Basri Johan Jeet Abdullah, Kwan Hoong Ng, Li Kuo Tan & Jeannie Hsiu Ding Wong. 2010. Temporal Registration of Radiofrequency Information and CT Images for Radiofrequency Ablation Procedure. Journal of Mechanics in Medicine and Biology. DOI: 10.1142/S0219519410003642
  29. Kadri NA, Tan LK, Ng KH. Riding on the crest of electronic publishing wave. Biomed Imaging Interv J 2009; 5(1):e1
  30. Tan, C. T., & Tan, L. K. (2007). Free on-line journals - Is this the solution for developing countries? EPILEPSIA, 48(7), 14.
  31. LK Tan. Image file formats. 2006 Biomedical Imaging and Intervention Journal. 2(1):e6
  32. Tan LK, Wong JHD, Ng KH.2006. A Low-Cost, High-Quality Method for Remote Recording of Presentations.American J Roentgenology 186(3):898-901.
Other Publications
  1. N Ramli, YQ Wong, A Vijayanathan, LK Tan, MP Tan. Assessment of white matter lesions and WM tracts integrity in older falls using advanced MRI techniques. NEURORADIOLOGY (2015) 57 (SUPPL 1): S153 - Extended Abstract
  2. N. Ramli , A. K., PC Seow , LK Tan , JHD Wong , D Ganesan. Chemical Shift Gradient Echo In- and Opposed-Phase Sequences in 3 T MRI for the Detection of H-MRS Visible Lipids and Grading of Gliomas. NEURORADIOLOGY (2015) 57 (SUPPL 1): S119 - Extended Abstract
  3. N. Ramli , M. C. L., V. Veeramuthu , L.K. Tan , V. Narayanan , K. Azmi. A Longitudinal Study of Diffusion Tensor Imaging in Mild Traumatic Brain Injury: Complicated Versus Non-Complicated. NEURORADIOLOGY (2015) 57 (SUPPL 1): S153 - Extended Abstract
  4. Veeramuthu, V, Tan, L.K, Narayanan, V, Waran, V, Ramli, N, Ganesan, D. Diffused tensor imaging metrics in acute mild traumatic brain injury and its correlation with early neuropsychological impairment. Conference: 32nd Annual National Neurotrauma Symposium Location: San Francisco, CA Date: JUN 29-JUL 02, 2014 JOURNAL OF NEUROTRAUMA Volume: 31 Issue: 12 Pages: A33-A33 Meeting Abstract: A2-25 - Extended Abstract

RESEARCH PROJECT

National
  1. 2013 - 2015, Geran Penyelidikan Universiti Malaya (UMRG)
    WHITE MATTER MATURATION IN CHILDREN WITH DEVELOPMENTAL DELAY USING DIFFUSION TENSOR IMAGING ( Consultant)
  2. 2011 - 2014, NONE
    Alexithymia in conversion disorder ( Consultant)
  3. 2011 - 2013, High Impact Research (HIR)
    Evaluation of Chemical Shift Echo squence in 3T MRI in detection of H-MRS visible lipids in Intracranial tumour ( Consultant)
  4. 2005 - 2006, PERSONAL
    Low-Cost, High Quality, Remote Recording of Presentations ( PROJECT LEADER)
  5. 2005, PERSONAL
    Mammogram Feature Classification ( Principal Investigator(PI))
  6. 2004 - 2005, Short Term Research Fund (Vote F)(PJP)
    CR and DR Image Quality Evaluation ( Co-Researcher)
  7. 2004 - 2005, Short Term Research Fund (Vote F)(PJP)
    Mammogram Tumour Mass Characterisation ( Co-Researcher)
International
  1. 2006, EXTERNAL
    WHO EMF Education Portal ( Principal Investigator(PI))
  2. 2006 - 2006, World Health Organization
    Web-Based Educational Portal on EMF for Children ( Consultant)
  3. 2004 - 2005, UNSURE
    IAEA Gafchromic Study ( Principal Investigator(PI))

PAPER PRESENTED

INVITED SPEAKER
  1. Radiomics: Walkthrough of a Sample Workflow, 18th Asia-Oceania Congress of Medical Physics (AOCMP) and 16th South-East Asia Congress of Medical Physics (SEACOMP), International Organization for Medical Physics, Asia-Oceania Federation of Organizations for Medical Physics, South-East Asian Federation of Organizations for Medical Physics, ASEAN College of Medical Physics, Malaysian Institute of Physics (International) (11 Nov 2018 - 14 Nov 2018)
POSTER PRESENTER
  1. Implementation of a pipeline for seamless analysis of DTI data, College of Radiology Annual Scientific Meeting 2011, College of Radiology, Malaysia (National) (08 Apr 2011 - 10 Apr 2011)
PRESENTER
  1. Implementing routine dose surveys for computed tomography (CT) systems via DICOM metadata, 13th Asia-Oceania Congress of Medical Physics & 11th South-East Asian Congress of Medical Physics, Asia-Oceania Federation of Medical Physics & South-East Asian Federation of Medical Physics (International) (12 Dec 2013 - 14 Dec 2013)

SUPERVISION

Postgraduate Student
Master
  1. (2013) (draft) Registration of radiotherapy QA film to TPS report, Janatul Madinah Wahabi
  2. (2012) Development and implementation of an automatic counting system for CR-39 solid state nuclear track detectors, Moayyad AlSabbagh
  3. (2009) Comparison of angular dependence of the luminance and contrast in medical and consumer LCD, Lim Sze Yuan (University of Malaya (UM))
  4. (2008) A Comparison Of Protocols For Diagnostic Radiology Dosimetry In Mammography, General Radiography And Dentral Radiography: Iaea Technical Report Series No. 457, Aapm Report No. 31, Ipem Report No. 91, Acr And Eu Protocol, Marianie binti Musarudin
  5. (2007) Skin and eye dose measurement for head and neck radiotherapy using Gafchromic EBT film, Lim Hao Seng (University of Malaya (UM))
  6. (2007) Ex-vivo study of radiofrequency ablation system at the University of Malaya Medical Centre, Loh Li Miin (University of Malaya (UM))
  7. (2007) Detection and measurement of colonic polyps by multidetector computed tomography colonoscopy - a phantom study, Noorazrul Azmie bin Yahya (University of Malaya (UM))
  8. (2007) Comparison of dose and image quality between flat panel detector and image intensifier and digital radiography system, Wan Hazlinda binti Ismail
  9. (2007) Automated electrophysiological quantification of hemifacial spasm, Wong Yun Chun (University of Malaya (UM))
  10. (2004) Evaluation of Imaging Quality of a Computed Radiography Unit, Hiew Ching Ching (University of Malaya (UM))

TEACHING

Master
  1. (2012) Radiology Physics
  2. (2012) MQGQ6102 - Biostatistics
  3. (2012) MQGQ6103 - Computing and Medical Informatics
  4. (2010) Radiology Physics
  5. (2010) MQGQ6107 - Medical Imaging
  6. (2010) MQGQ6109 - Nuclear Medicine
  7. (2010) MQGQ6189 - Dissertation
  8. (2009) Radiology Physics
  9. (2009) MQGQ6102 - Biostatistics
  10. (2009) MQGQ6103 - Computing and Medical Informatics
  11. (2009) MQGQ6107 - Medical Imaging
  12. (2009) MQGQ6109 - Nuclear Medicine
  13. (2009) MQGQ6189 - Dissertation
Bachelor
  1. (2012) MPEP1123 - Applied Physics
  2. (2012) MPEP4121 - Medical Informatics
  3. (2011) KUEU4135 - Management and Clinical Engineering
  4. (2010) KUEU4135 - Management and Clinical Engineering
  5. (2010) MVEB2401 - Nuclear Med Tech: Intermediate Course (B)
  6. (2009) KUEU3150 - Biomedical Engineering Practices
  7. (2009) KUEU4135 - Management and Clinical Engineering
  8. (2009) MVEB2101 - Nuclear Medicine Technology : Basic Course
  9. (2009) MVEB2401 - Nuclear Med Tech: Intermediate Course (B)
  10. (2008) MVEB2101 - Nuclear Medicine Technology : Basic Course

SOCIAL RESPONSIBILITY ACTIVITIES

  • Deacon, Translator, Sunday School Teacher, Worship Leader, and Musician At Jalan 3 Gospel Hall Church., (01 Jan 2005 - 31 Dec 2018)
  • Webmaster of Neurology Asia Journal, (01 Jan 2004 - 31 Dec 2018)