
Curriculum Vitae
PROF. DR. LIM SHEN-YANG
Professor
- Department of Medicine
Faculty of Medicine - +603-79492350
- limshenyang@um.edu.my
I am a Consultant Neurologist and Professor at the University of Malaya, Kuala Lumpur, where I run a very busy government clinic and private practice seeing many patients (around 70+ every week) with Parkinson’s disease (PD) and other Movement Disorders. I earned my medical and research doctorate degrees from the University of Melbourne and was admitted to Fellowship of the Royal Australasian College of Physicians after completing advanced training in adult Internal Medicine and Neurology in Melbourne. I trained in Parkinson’s & Movement Disorders at world-renowned centres in Melbourne and Toronto. I have published widely in the field of Movement Disorders (Parkinson's as well as a variety of rarer movement disorders), with >100 peer-reviewed journal papers and book chapters, including first-author publications in Lancet Neurology, Archives of Neurology/JAMA Neurology, Movement Disorders, etc. and co-authorship in journals such as Nature Genetics, Annals of Neurology and Brain (>4,000 citations, h-index 29). I am on several journal Editorial Boards and Associate Editor for Science Advances and Neurology Asia.
I am the Chair-Elect (previously Honorary Secretary, and Education Committee Chair) of the MDS Asian-Oceanian section of the International Parkinson & Movement Disorder Society (MDS), and serve on several MDS Committees/Task Forces (for Evidence-Based Medicine; Palliative Care; Movement Disorders in Asia; PD Diagnostic Criteria; etc.). I am a Working Group Co-Lead within the Global Parkinson's Genetics Program (GP2). I am a holder (and reviewer) of grants for PD-related funding organisations such as the Michael J. Fox Foundation (MJFF).
With a strong commitment to teaching/training, I have organized numerous teaching courses on Parkinson’s & Movement Disorders, and delivered and/or participated in >200 international-level lectures and expert panels (in the United States, Canada, United Kingdom, Germany, France, Australia, Japan, Singapore, China, India, South Korea, Hong Kong, Taiwan, Thailand, Indonesia, Philippines, Sri Lanka, Brunei, Myanmar, United Arab Emirates, Kyrgyzstan, Mongolia, etc.). These have often been under the auspices of the MDS, as MDS Visiting Professor, MDS Ambassador, or MDS Virtual Professor. I have given numerous Plenary Lectures, including at MDS Congresses (Toronto 2011, Dublin 2012, Nice 2019, Philadelphia (Virtual) 2020) and at the World Parkinson's Congress (Kyoto 2019). I am Medical Advisor to the Malaysian Parkinson’s Disease Association, and a founding member (and current Chair) of the Malaysian Movement Disorder Council. I was part of the 4-strong team representing Malaysia that beat 13 other national teams to win the Tournament of the Minds at the 19th World Congress of Neurology in 2009. I was elected as a Fellow of the Malaysian Academy of Sciences in 2017. In recognition of my leadership in the Movement Disorders field, I was invited to be an Expert Panelist/Consultant to the World Health Organization (WHO) in 2020 (ongoing) to address global policy, implementation and research related to PD.
My main research interests are in the following areas: (i) PD (particularly genetics; evidence-based medicine/clinical trials; non-motor features including gastrointestinal aspects; comorbidities; patient-centred care; and rating scales); (ii) Parkinson-plus syndromes; and (iii) Miscellaneous/"orphan" movement disorders.
(Qualification),(Field),(Institution),(Year)
- M.D. (Doctor of Medicine, by research thesis), NEUROLOGY(Movement disorders, including Parkinson disease), UNIVERSITY OF MELBOURNE, AUSTRALIA
- Fellowship (Parkinson Disease & Movement Disorders), NEUROLOGY(Parkinson Disease & Movement Disoders), TORONTO UNIVERSITY, CANADA
- Fellowship (Parkinson Disease & Movement Disorders), NEUROLOGY(Parkinson disease & Movement Disorders), UNIVERSITY OF MELBOURNE, AUSTRALIA
- FRACP (Fellowship of the Royal Australasian College of Physicians), ADULT MEDICINE DIVISION(Internal Medicine and Neurology), ROYAL AUSTRALIASIAN COLLEGE OF PHYSICIANS
- MB,BS (Bachelor of Medicine & Bachelor of Surgery), LAIN-LAIN(BACHELOR OF MADECINE AND BACHELOR OF SURGERY), UNIVERSITY OF MELBOURNE, AUSTRALIA
(Area)
(Title of publication in APA style)
- Tan AH, Chong CW, Lim SY, Yap IKS, The CSJ, Loke MF, Song SL, Tan JY, Ang BH, Tan YQ, Kho MT, Bowman J, Mahadeva S, Yong HS, Lang AE. Gut microbial ecosystem in Parkinson s disease: New clinico-biological insights from multi-omics. Annals of Neurology. 2021; 89:546-559. (Impact factor 9.0 in 2019). (WoS)
- Tan AH, Lim SY, Chong KK, Azhan A Manap MA, Hor JW, Lim JL, Low SC, Chong CW, Mahadeva S, Lang AE. Probiotics for constipation in Parkinson s disease: A randomized placebo-controlled study. Neurology. 2021;96:e772-e782 (Impact factor 8.8 in 2019). (WoS)
- Tan AH, Hor JW, Chong CW, Lim SY. Probiotics for Parkinson s disease: Current evidence and future directions. (Invited article). Journal of Gastroenterology & Hepatology Open. 2021; 5(4):414-419. (SCOPUS)
- Lim SY, Ahmad-Annuar A, Lohmann K, Tan AH, Tay YW, Lim JL, Lim KB, Lit LC, Bauer P, Rolfs A, Klein C. Clinical phenotype of Parkinson's disease with a homozygous PRKN p.Cys441Arg mutation. Neurology Asia. In press. (WoS)
- Lim SY, Jasti DB, Tan AH. Improvement of "Bouncy Gait" in Lance-Adams Syndrome with Perampanel. Cureus. 2020 Jan 25;12(1):e6773. doi: 10.7759/cureus.6773. (WoS)
- Choo XY, Lim SY, Chinna K, Tan YJ, Yong VW, Lim JL, Lau KF, Chung JY, Em JM, Tan HT, Lim JH, Tan SB, Tan CT, Tan AH. Understanding patients' and caregivers perspectives and educational needs in Parkinson s disease: A multi-ethnic Asian study. Neurol Sci. Apr 20. doi: 10.1007/s10072-020-04396-4. [Epub ahead of print] (Impact factor 2.5 in 2018). (WoS)
- Bhidayasiri R, Panyakaew P, Trenkwalder C, Jeon B, Hattori N, Jagota P, Wu YR, Moro E, Lim SY, Shang H, Rosales R, Lee JY, Thit WM, Tan EK, Lim TT, Tran NT, Binh NT, Phoumindr A, Boonmongkol T, Phokaewvarangkul O, Thongchuam Y, Vorachit S, Plengsri R, Chokpatcharavate M, Fernandez HH. Delivering patient-centered care in Parkinson's disease: Challenges and consensus from an international panel. Parkinsonism Relat Disord. 2020 Feb 27;72:82-87. doi: 10.1016/j.parkreldis.2020.02.013. [Epub ahead of print]. (Impact factor 4.36 in 2020). (WoS)
- Tan AH, Lim SY, Mahadeva S, Loke MF, Tan JY, Ang BH, Chin KP, Mohammad Adnan AF, Ong SMC, Ibrahim AI, Zulkifli N, Lee JK, Lim WT, Teo YT, Kok YL, Ng TY, Tan AGS, Zulkifle IM, Ng CK, Ee SS, Arafin S, Mohamad Shukori K, Vadivelu JS, Marras C, Fox SH, Lang AE. Helicobacter pylori eradication in Parkinson's disease: a randomized placebo-controlled trial. Movement Disorders. 2020;35(12):2250-2260. (Impact factor 8.3 in 2020). (WoS)
- Mohd Fauzi NA, Abdullah S, Tan AH, Mohd Ramli N, Tan CY, Lim SY. Relapsing encephalopathy with dancing eyes and jerky limbs. Parkinsonism & Related Disorders. 2020;75:110-113. (ISI-Cited; Impact factor 4.7 in 2019). (WoS)
- Chan CHS, Albanese A, Chaudhuri KR, Opal P, Wu YC, Jeon BS, Truong D, Poewe W, Tan L, Pal P, Colosimo C, Lim SY, Jinnah H, Cardoso F. Neurological research & training after the easing of lockdown in countries impacted by COVID-19. Journal of Neurological Sciences. 2020;418:117105. (Impact factor 3.1 in 2019). (WoS)
- Tan EK, Albanese A, Chaudhuri K, Lim SY, Oey NE, Shan Chan CH, Wu YC, Jeon B, Truong D, Poewe W, Pal PK, Tan L, Opal P, Colosimo C, Jinnah HA, Cardoso F. Adapting to post-COVID19 research in Parkinson's disease: Lessons from a multinational experience. Parkinsonism Relat Disord. 2020 Oct 7:S1353-8020(20)30780-X. doi: 10.1016/j.parkreldis.2020.10.009. Online ahead of print. (Impact factor 3.9 in 2020). (WoS)
- Tan AH, Lohmann K, Tay YW, Lim JL, Ahmad-Annuar A, Ramli N, Chin YT, Mawardi AS, Azmi K, Abdul Aziz Z, Datuk Puvanarajah S, Bauer P, Klein C, Rolfs A, Lim SY. PINK1 p.Leu347Pro mutations in Malays: Prevalence and Illustrative Cases. Parkinsonism & Related Disorders. 2020;79:34-39. (Impact factor 4.35 in 2020). (WoS)
- Lim SY, Lim JL, Ahmad-Annuar A, Lohmann K, Tan AH, Lim KB, Tay YW, Shing YL, Muthusamy KA, Bauer P, Rolfs A, Klein C. Clinical phenotype of LRRK2 R1441C in two Chinese sisters. Neurodegenerative Diseases. 2020 Jun 24:1-7. doi: 10.1159/000508131. (Impact factor 2.8 in 2019). (WoS)
- Lim SY, Ahmad-Annuar A, Lohmann K, Tan AH, Lim JL, Tay YW, Ramli N, Teh PC, Tan CT, Goh KJ, Viswanathan S, Kuppusamy R, Bauer P, Rolfs A, Klein C. Parkinson's disease with homozygous PINK1 p.Leu489Pro mutations in two Indian sisters. Neurology Asia. In press. (WoS)
- Foo JN, Chew EGY, Chung SJ, Annuar AA, Lim JL, Tan AH, Lim SY, Khor CC, Liu J, Tan EK. Identification of Risk Loci for Parkinson Disease in Asians and Comparison of Risk Between Asians and Europeans: A Genome-Wide Association Study. JAMA Neurology 2020;77(6):746-754. (Impact factor 12.3 in 2018). (WoS)
- Lim SY, Ishiura H, Ramli N, Shibata S, Almansour MA, Tan AH, Houlden H, Lang AE, Tsuji S. Adult-onset neuronal intranuclear inclusion disease mimicking Fragile X-associated tremor-ataxia syndrome in ethnic Chinese patients. Parkinsonism Relat Disord. 2020;74:25-27. (Impact factor 4.35 in 2020). (WoS)
- Tay YW, Lim JL, Tan AH, Ahmad-Annuar A, Lim SY. Rare homozygous exon 8 and 9 PRKN deletion in Malay familial early-onset Parkinson s disease. Annals of the Academy of Medicine Singapore. (Impact factor 0.9 in 2020). In press. (WoS)
- Lim SY, Lim KB, Hor JW, Tan AH. Brief clinical rating scales should not be overlooked. Movement Disorders. 2020;35(10):1884-1885. (Impact factor 8.22 in 2020). (WoS)
- Yong VW, Tan YJ, Ng YD, Choo XY, Sugumaran K, Chinna K, Md Shah MN, Raja Aman RRA, Moy FM, Mohd Ramli N, Grossmann M, Lim SY, Tan AH. Progressive and accelerated weight and body fat loss in Parkinson's disease: a three-year prospective longitudinal study. Parkinsonism & Related Disorders. 2020;77:28-35. (Impact factor 4.4 in 2020). (WoS)
- Tan YJ, Lim SY, Yong VW, Choo XY, Ng YD, Sugumaran K, Md Shah MN, Raja Aman RRA, Paramasivam SS, Mohd Ramli N, Grossmann M, Tan AH. Osteoporosis in Parkinson's disease: relevance of distal radius dual-energy x-ray absorptiometry (DXA) and sarcopenia. Journal of Clinical Densitometry. 2020 Jul 30:S1094-6950(20)30110-4. (Impact factor 2.3 in 2020). (WoS)
- Fong SL, Tan AH, Lau KF, Ramli N, Lim SY. Hyperglycemia-associated hemichorea-hemiballismus with predominant ipsilateral putaminal abnormality on neuroimaging. Journal of Movement Disorders. 2019;12(3):187-189. (ISI-cited) (WoS)
- Gopalai AA, Lim JL, Li HH, Zhao Y, Lim TT, Eow GB, Puvanarajah S, Viswanathan S, Norlinah MI, Abdul Aziz Z, Lim SK, Tan CT, Tan AH, Lim SY, Tan EK, Ahmad Annuar A. LRRK2 N551K and R1398H variants are protective in Malays and Chinese in Malaysia: A case-control association study for Parkinson's disease. Molecular Genetics & Genomic Medicine. 2019;7(11):e604. (Impact factor 2.45 in 2019). (WoS)
- Seppi K, Chaudhuri KR, Coelho M, et al. Update on treatments for the non-motor symptoms of Parkinson s disease: an evidence-based medicine review. Movement Disorders 2019;34(2):180-198. (Impact factor 8.32 in 2018). (WoS)
- Chew EGY, Liany H, Tan LCS, Au WL, Prakash KM, Ahmad Annuar A, Chan AYY, Lim SY, Mok V, Chung SJ, Song K, Liu J, Foo JN, Tan EK. Evaluation of novel Parkinson s disease candidate genes in the Chinese population. Neurobiology of Aging. 2019;74:235.e1-235.e4. (Impact factor 4.45 in 2018) (WoS)
- Lubomski M, Tan AH, Lim SY, Holmes AJ, Davis RL, Sue CM. Parkinson s disease and the gastrointestinal microbiome. Journal of Neurology 2019. E-pub ahead of print: https://doi.org/10.1007/s00415-019-09320-1. (Impact factor 3.78 in 2017). (WoS)
- Chelban V, ... Houlden H, ... SYNaPS Study Group. PDXK mutations cause polyneuropathy responsive to pyridoxal 5'-phosphate supplementation. Annals of Neurology 2019;86(2):225-240 (Impact factor in 10.2 in 2017). (WoS)
- Evans AH, Okai D, Weintraub D, Lim SY, O Sullivan S, Voon V, Krack P, Sampaio C, Post B, Leentjens A, Martinez-Martin P, Stebbins GT, Goetz CG, Schrag A, Members of the IPMDS Rating Scales Review Committee. Scales to assess impulsive and compulsive behaviors in Parkinson s disease: critique and recommendations. Movement Disorders. 2019;34(6):791-798.(Impact factor 8.32 in 2018). (WoS)
- Tan AH, Ong TL, Ramli N, Tan LK, Lim JL, Azhan MA, Ahmad-Annuar A, Ibrahim KA, Abdul-Aziz Z, Ozelius LJ, Brashear A, Lim SY. Alternating hemiplegia of childhood in a person of Malay ethnicity with diffusion tensor imaging abnormalities. Journal of Movement Disorders. 2019;12(2):132-134. (WoS)
- Ishiura H, Shibata S, Yoshimura J, Suzuki Y, Qu W, Doi K, Almansour MA, Kikuchi J, Taira M, Mitsui J, Takahashi Y, Ichikawa Y, Mano T, Iwata A, Harigaya Y, Matsukawa MK, Matsukawa T, Tanaka M, Shirota Y, Ohtomo R, Kowa H, Date H, Mitsue A, Hatsuta H, Morimoto S, Murayama S, Shiio Y, Saito Y, Mitsutake A, Kawai M, Sasaki T, Sugiyama Y, Hamada M, Ohtomo G, Terao Y, Nakazato Y, Takeda A, Sakiyama Y, Umeda-Kameyama Y, Shinmi J, Ogata K, Kohno Y, Lim SY, Tan AH, Shimizu J, Goto J, Nishino I, Toda T, Morishita S, Tsuji S. Noncoding CGG repeat expansions in neuronal intranuclear inclusion disease, oculopharyngodistal myopathy and an overlapping disease. Nature Genetics. 2019;51(8):1222-1232 (Impact factor 27.1 in 2017). (WoS)
- Lim SY, Tan AH, Annuar AA, Klein C, Tan LCS, Rosales R, Bhidayasiri R, Wu YR, Shang HF, Evans AH, Pal PK, Hattori N, Tan CT, Jeon B, Tan EK, Lang AE. Parkinson's disease in the Western Pacific Region. Lancet Neurology. 2019;18(9):865-879. (Impact factor 27.1 in 2019 - the #1-ranked journal in clinical neurology). (WoS)
- Vollstedt EJ, Kasten M, Klein C; MJFF Global Genetic Parkinson's Disease Study Group. Using global team science to identify genetic Parkinson's disease worldwide. Annals of Neurology. 2019;86(2):153-157. (Impact factor 10.2 in 2017) (WoS)
- Efthymiou S, ... SYNAPS Study Group, ... Houlden H. Biallelic mutations in neurofascin cause neurodevelopmental impairment and peripheral demyelination. Brain. 2019;142(10):2948-2964. (Impact factor 11.8 in 2018). (WoS)
- B Xiao, X Deng, EYL Ng, JC Allen Jr, SY Lim, A Ahmad-Annuar, EK Tan. LRRK2 haplotype lowers age at onset in Parkinson s disease. JAMA Neurology. 2018;75(1):127-128. (Impact factor 10.0 in 2017). (WoS)
- AH Tan, TH Toh, SC Low, SL Fong, KK Chong, KW Lee, KJ Goh, SY Lim. Chorea in Sporadic Creutzfeldt-Jakob disease. Journal of Movement Disorders. 2018;11(3):149-151. (WoS)
- Tan AH, Hew YC, Lim SY, Ramli NM, Kamaruzzaman SB, Tan MP, Grossmann M, Ang BH, Tan JY, Manap MAA, Tay TK, Tan SL, New RP, Fadzli F, Yee EJ, Moy FM, Mahadeva S, Lang AE. Altered body composition, sarcopenia, frailty, and their clinico-biological correlates, in Parkinson s disease. Parkinsonism & Related Disorders. 2018;56:58-64. (Impact factor 4.5 in 2017). (WoS)
- SY Lim, AH Tan, A Ahmad-Annuar, SA Schneider, PC Bee, JL Lim, N Ramli, MI Idris. A Patient with Beta-Propeller Protein-Associated Neurodegeneration (BPAN): Treatment with Iron Chelation Therapy. Journal of Movement Disorders. 2018;11(2):89-92. (WoS)
- SY Lim, AH Tan, JL Lim, A Ahmad-Annuar. Purposeless Groaning in Parkinson's Disease. Journal of Movement Disorders. 2018;11(2):87-88. (WoS)
- AH Tan, Chong CW, Song SL, The SCJ, Yap IKS, Loke MF, Tan YQ, Yong HS, Mahadeva S, Lang AE, Lim SY. Altered gut microbiome and metabolome in patients with multiple system atrophy. Movement Disorders. 2018;33(1):174-176. (Impact factor 8.32 in 2018). (WoS)
- Fox SH, Katzenschlager R, Lim SY, Barton B, de Bie RMA, Seppi K, Coelho M, Sampaio C, MDS EBM Committee. International Parkinson and Movement Disorder Society Evidence-Based Medicine Review: Update on Treatments for the Motor Symptoms of Parkinson s Disease. Movement Disorders 2018;33(8):1248-1266. (Impact factor 8.32 in 2018). (WoS)
- Tan AH, Lim SY, Ng RX. Osmotic demyelination syndrome with evolving movement disorders. JAMA Neurology 2018;75(7):888-889. (Impact factor 10.0 in 2017). (WoS)
- Lim SY, Tan AH. Historical Perspective: The Pros and Cons of Conventional Outcome Measures in Parkinson's Disease. Parkinsonism & Related Disorders 2017;46:S47-S52. (Impact factor 4.48 in 2017). (WoS)
- Foo JN, Tan LC, Irwan ID, Au WL, Low HQ, Prakash KM, Ahmad-Annuar A, Bei J, Chan AYY, Chen CM, Chen YC, Chung SJ, Deng H, Lim SY, Mok V, Pang H, Pei Z, Peng R, Shang HF, Song K, Tan AH, Wu YR, Aung T, Cheng CY, Chew FT, Chew SH, Chong SA, Ebstein RP, Lee J, Saw SM, Seow A, Subramaniam M, Tai ES, Vithana EN, Wong TY, Heng KK, Meah WY, Khor CC, Liu H, Zhang F, Liu J, Tan EK. Genome-wide association study of Parkinson disease in East Asians. Human Molecular Genetics. 2017;26(1):226-232 (Impact factor 5.98 in 2016). (WoS)
- Lim SY, Poewe W, Tan AH. Levodopa and Parkinson's Disease - Myths Revisited. JAMA Neurology. 2017;74(10):1270. (Impact factor 10.0 in 2017). (WoS)
- Sauerbier A, Jitkritsadakul O, Titova N, Klingelhoefer L, Tsuboi Y, Carr H, Kumar H, Banerjee R, Erro R, Bhidayasiri R, Schrag A, Zis P, Lim SY, Al-Hashel JY, Kamel WA, Martinez-Martin P, Chaudhuri KR. Non-motor symptoms assessed by Non-Motor Symptoms Questionnaire and Non-Motor Symptoms Scale in Parkinson s disease in selected Asian populations. Neuroepidemiology 2017;49:1 17. (Impact factor 2.56 in 2017). (WoS)
- Lim SY, Tan AH, Fox SH, Evans AH, Low SC. Integrating Patient Concerns into Parkinson's Disease Management. Current Neurology & Neuroscience Reports. 2016;17(1):3. (Impact Factor 3.1 in 2014) (WoS)
- Tan AH, Low SC, Tan CY, Lim KS, Tan CT, Lim SY. "Ictal Catatonia": Rare but not to be missed! Parkinsonism & Related Disorders. 2016;32:137-139. (ISI-Cited; Impact factor 4.13 in 2014) (WoS)
- Low SC, Tan AH, Lim SY. Purposeless Groaning in Progressive Supranuclear Palsy. Neurology. 2017;88(1):e9. (Impact factor 8.3 in 2014). (WoS)
- Liong CC, Kartini R, Mah JSY, Lim SY, Tan AH. Non-alcoholic Wernicke encephalopathy: an entity not to be missed! Canadian Journal of Neurological Sciences. 2016;43(5):719-720. (ISI-cited; Impact factor 1.53 in 2016). (WoS)
- Lim SY, Wadia PM, Armstrong MJ, Schenck CH, Lang AE. Augmented restless legs syndrome with marked hyperkinesias and impulsive-compulsive behaviors. Movement Disorders Clinical Practice (Official journal of the International Parkinson's & Movement Disorder Society). 2016;3(4)412-414. (WoS)
- Suwarnalata G, Tan AH, Isa H, Gudimella R, Anwar A, Loke MF, Mahadeva S, Lim SY, Vadivelu J. Augmentation of Autoantibodies by Helicobacter pylori in Parkinson's Disease Patients May Be Linked to Greater Severity. PLoS One 2016;11(4):e0153725. (ISI-Cited; Impact factor 3.2 in 2014) (WoS)
- Gopalai AA, Ahmad-Annuar A, Li HH, Zhao Y, Lim SY, Tan AH, Lim TT, Eow GB, Santhi P, Shanthi V, Norlinah MI, Aziz ZA, Lim SK, Tan CT, Tan EK. PARK16 is associated with PD in the Malaysian population. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 2016;171(6):839 847. (ISI-cited; Impact factor 3.42 in 2016). (WoS)
- Tan AH, Mahadeva S, Marras C, Thalha AM, Kiew CK, Yeat CM, Ng SW, Ang SP, Chow SK, Loke MF, Vadivelu JS, Ibrahim N, Yong HS, Tan CT, Fox SH, Lang AE, Lim SY. Helicobacter pylori infection is associated with worse severity of Parkinson disease. Parkinsonism & Related Disorders 2015;21:221-225. (Impact factor 4.13 in 2014). (WoS)
- Tan AH, Mah JSY, Thong MK, Lim SY. Methylmalonic Aciduria: A Treatable Disorder of Which Adult Neurologists Need to Be Aware. Movement Disorders Clinical Practice (Official journal of the International Parkinson's & Movement Disorder Society) 2015;3(1):104-105. (WoS)
- Ramli N, Nair SR, Ramli NM, Lim SY. Differentiating multiple-system atrophy from Parkinson disease. Clinical Radiology 2015;70(5):555-564. (Impact factor 1.66 in 2015). (WoS)
- Tan AH, Tan CT, Marras C, Loh KW, Ho NWW, Lim QH, Tan PW, Lim CC, Cheong YW, Kong ST, Schee JP, Tan KH, Soo SK, Vanderschaaf C, Lew SLH, Mahamad UA, Goh KJ, Yong HS, Lim SY. Knowledge of Parkinson's disease in a multiethnic urban Asian setting. Journal of Parkinson's disease 2015;5:865-879. (Impact factor 1.91 in 2014). (WoS)
- Tan AH, Linn K, Sam I-C, Tan CT, Lim SY. Opsoclonus-myoclonus-ataxia syndrome associated with Dengue Virus infection (Letter in Reply). Parkinsonism & Related Disorders 2015;21:160-161. (Impact factor 4.13 in 2014) (WoS)
- Zainal Abidin S, Tan EL, Chan SC, Jaafar A, Lee AX, Abd Hamid MH, Abdul Murad NA, Pakarul Razy NF, Azmin S, Ahmad Annuar A, Lim SY, Cheah PS, Ling KH, Mohamed Ibrahim N. DRD and GRIN2B polymorphisms and their association with the development of impulse control behaviour among Malaysian Parkinson's disease patients. BMC Neurology 2015;15:59. (Impact factor 2.04 in 2015). (WoS)
- Yap AC, Mahamad UA, Lim SY, Kim HJ, Choo YM. Coumarin-based Fluorescent Sensor for Central Nervous System Disease Biomarker. Sensors 2014;14(11):21140-50. (Impact factor 2.05 in 2013). (WoS)
- Tan AH, Ozelius LJ, Brashear A, Lang AE, Ahmad-Annuar A, Tan CT, Lim SY. Rapid-Onset Dystonia-Parkinsonism in a Chinese Girl with a De Novo ATP1A3 c.2267G>A (p.R756H) Genetic Mutation. Movement Disorders Clinical Practice 2014. doi:10.1002/mdc3.12122
- Tan AH, Linn K, Mohd. Ramli N, Hlaing CS, AMM, Sam I-C, Ng CG, Goh KJ, Tan CT, Lim SY. Opsoclonus-myoclonus-ataxia syndrome associated with Dengue Virus infection. Parkinsonism & Related Disorders 2014;20:1309-1310. (Impact factor 4.13 in 2014). (WoS)
- Foo JN, Tan LC, Liany H, Koh TH, Irwan ID, Ng YY, Ahmad-Annuar A, Au WL, Aung T, Chan AY, Chong SA, Chung SJ, Jung Y, Khor CC, Kim J, Lee J, Lim SY, Mok V, Prakash KM, Song K, Tai ES, Vithana EN, Wong TY, Tan EK, Liu J. Analysis of nonsynonymous coding variants of Parkinson disease-related pathogenic and susceptibility genes in East Asian populations. Human Molecular Genetics. 2014;23(14):3891-7. (Impact factor 7.69 in 2014). (WoS)
- Tan AH, Mahadeva S, Thalha AM, Gibson PR, Kiew CK, Yeat CM, Ng SW, Ang SP, Chow SK, Tan CT, Yong HS, Marras C, Fox SH, Lim SY. Small intestinal bacterial overgrowth in Parkinson disease. Parkinsonism & Related Disorders 2014;20:535-540. (Impact factor 4.13 in 2014). (WoS)
- Gopalai AA, Lim SY, Chua JY, Tey S, Lim TT, Ibrahim NM, Tan AH, Eow GB, Aziz ZA, Puvanarajah S, Viswanathan S, Looi I, Lim SK, Tan LP, Chong YB, Tan CT, Zhao Y, Tan EK, Ahmad-Annuar A. LRRK2 G2385R and R1628P mutations are associated with an increased risk of Parkinson disease in the Malaysian population. BioMed Research International 2014, Article ID 867321. (Impact factor 2.88 in 2013). (WoS)
- Chan HF, Kukkle PL, Merello M, Lim SY, Poon YY, Moro E. Amantadine improves gait in PD patients with STN stimulation. Parkinsonism & Related Disorders 2013;19(3):316-319. (Impact factor 3.79 in 2012). (WoS)
- Shahrizaila N, Mahamad UA, Yap AC, Choo YM, Marras C, Lim SY. Is chronic levodopa therapy associated with distal symmetric polyneuropathy in Parkinson disease? Parkinsonism & Related Disorders 2013;19:391-393. (Impact factor 3.79 in 2012). (WoS)
- Nair SR, Tan LK, Mohd Ramli N, Lim SY, Rahmat K, Mohd Nor H. A decision tree for differentiating multiple system atrophy from Parkinson's disease using 3-T MR imaging. European Radiology 2013;23(6):1459-1466. (IF 4.34 in 2013). (WoS)
- Zhao Y, Gopalai A, Ahmad-Annuar A, Teng E, Prakash K, Tan L, Au WL, Li HH, Lim SY, Lim S, Chong Y, Tan L, Ibrahim N, Tan EK. Association of HLA locus variant in Parkinson disease. Clinical Genetics 2013;84(5):501-504. (Impact factor 3.1 in 2012). (WoS)
- Loh HC, Tang PY, Tee SF, Chow TJ, Choong CY, Lim SY, Yong HS. Neuregulin-1 (NRG-1) and its susceptibility to schizophrenia: A case-control study and meta-analysis. Psychiatry Research 2013;208(2):186-188. (Impact factor 2.52 in 2013). (WoS)
- Gopalai AA, Lim SY, Aziz ZA, Lim SK, Tan LP, Chong YB, Tan CT, Puvanarajah S, Viswanathan S, Kuppusamy R, Tan AH, Lim TT, Eow GB, Ibrahim NM, Li HH, Zhao Y, Ahmad-Annuar A. Lack of association between the LRRK2 A419V variant and Asian Parkinson disease. Annals Academy of Medicine Singapore 2013;42(5):237-240. (Impact factor 1.2 in 2011). (WoS)
- Tsang E, Hamani C, Moro E, Mazzella F, Saha U, Lozano AM, Hodaie M, Chuang R, Steeves TDL, Lim SY, Neagu B, Chen R. Subthalamic deep brain stimulation at individualized frequencies for Parkinson s disease. Neurology 2012;78:1930-1938. (Impact factor 8.17 in 2010). (WoS)
- Evans AH, Farrell MJ, Gibson SJ, Helme RD, Lim SY. Dyskinetic patients show rebound worsening of affect after an acute L-dopa challenge. Parkinsonism & Related Disorders 2012;18(5):514-519. (Impact factor 3.79 in 2012). (WoS)
- Lim SY, Ramli N, Tai SML, Nair SR. Involuntary movements in a recently-diagnosed elderly diabetic woman. Journal of Clinical Neuroscience 2011;18:539,590. (Impact factor 1.2 in 2009). (WoS)
- Tai SML, Tan CT, Ramli N, Begum RJ, Lim SY. Movement disorder in a patient with stroke. Journal of Clinical Neuroscience 2011;18:263,305. (Impact factor 1.2 in 2009). (WoS)
- Lim SY, Ismail I, Tai SML, Abdul Kadir KA, Tan LP. Chong YB, Shahrizaila N. Diffusion-weighted magnetic resonance imaging in a case of osmotic demyelination syndrome with fatal outcome. Neurology Asia 2011;16(1):89-92. (WoS)
- Loh KB, Rahmat K, Lim SY, Abdul Kadir KA, Ramli N. How I do it: Hot cross bun sign from diffusion tensor imaging and tractography perspective. Neurology India 2011;59(2):266-269. (Impact factor 1.09 in 2008). (WoS)
- Lim SY, Farrell MJ, Evans AH. Parkinson's disease and pain: Non-dopaminergic mechanisms are likely to be important too. Movement Disorders 2011;26(7):1353-1354. (Impact factor 4.0 in 2009). (WoS)
- Marras C, Schuele B, Munhoz RP, Rogaeva EA, Langston JW, Kasten M, Meaney C, Klein C, Wadia PM, Lim SY, Chuang RSI, Zadikoff C, Steeves T, Prakash KM, de Bie RMA, Adeli G, Thomsen T, Johansen KK, Teive H, Asante A, Reginold W, Lang AE. LRRK2-associated Parkinson s disease: Phenotype in parkinsonian and non-parkinsonian G2019S mutation carriers. Neurology 2011;77(4)325-333. (Impact factor 8.17 in 2010). (WoS)
- Chai CH, Lim SY, Abdul Kadir KA, Goh KJ, Tan CT. Karaoke, power failure and carbon monoxide poisoning. Neurology Asia 2011;16(3):255-257. (WoS)
- Abdullah S, Lim SY, Goh KJ, Lum LCS, Tan CT. Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis: A series of ten cases from a university hospital in Malaysia. Neurology Asia 2011;16(3):241-246. (ISI-cited). (WoS)
- Fox SH, Katzenschlager R, Lim SY, Ravina B, Seppi K, Coelho M, Poewe W, Rascol O, Goetz CG, Sampaio C. Movement Disorder Society evidence-based medicine review update: Treatments for the motor symptoms of Parkinson disease. Movement Disorders 2011;26(Suppl.3):S2-S41. (Impact factor 4.0 in 2009). (WoS)
- Lim SY, Tan ZK, Ngam PI, Lor TL, Mohamed H, Schee JP, Tan AK, Goh JY, Ooi E, Soh PCH. Impulsive-Compulsive Disorders are common in Asian Parkinson's disease patients: Assessment using the QUIP. Parkinsonism & Related Disorders 2011;17:761-764. (Impact factor 3.25 in 2011). (WoS)
- Lim SY, Zurowski M, Moro E. Impulsive-compulsive behaviours and subthalamic nucleus deep brain stimulation in Parkinson s disease. European Neurological Journal 2010;2(2). (New journal). (Non-WoS/Non-SCOPUS)
- Tai SML, Lim SY, Tan CT. Idiopathic paroxysmal kinesigenic dyskinesia in Malaysia, a multi-racial Southeast Asian country. Journal of Clinical Neuroscience 2010;17:1089-1090. (Impact factor 1.2 in 2009). (WoS)
- Lim SY, Lang AE. The nonmotor symptoms of Parkinson's disease: An overview. Movement Disorders 2010;25(Suppl. 1):S123-130. (Impact factor 4.0 in 2009). (WoS)
- Lim SY, Poon YY, Chen R, Mikulis D, Lozano AM, Moro E. Marked reduction of tremor in essential tremor after putaminal infarct. Journal of Neurology, Neurosurgery and Psychiatry 2010;81(10):1172-1173. (Impact factor 4.9 in 2009). (WoS)
- Lim SY, Hodaie M, Fallis M, Poon YY, Mazzella F, Moro E. Gamma knife thalamotomy for disabling tremor: A blinded evaluation. Archives of Neurology 2010;67 (5):584-588. (Impact factor 6.3 in 2009). (WoS)
- Wadia PM, Lim SY, Lozano AM, Adams JR, Poon YY, Diaz CT, Moro E. Bilateral pallidal stimulation for X-linked dystonia parkinsonism. Archives of Neurology 2010;67(8):1012-1015. (Impact factor 6.3 in 2009). (WoS)
- Lim SY,Goh KJ,Zain AA, Ramli N, Choo YM, Tan GH. Development of marked striatal hand with antiparkinsonian medication withdrawal during traditional (Ayurvedic) medicine treatment for Parkinson s disease. Neurology Asia 2010;15(3):275- 277 (WoS)
- Lim SY, O Sullivan SS, Kotschet K, Gallagher DA, Lacey C, Lawrence AD, Lees AJ, O Sullivan DJ, Peppard RF, Rodrigues JP, Schrag A, Silberstein P, Tisch S, Evans AH. DDS, ICDs and punding after DBS surgery for Parkinson's disease. Journal of Clinical Neuroscience 2009;16(9):1148-1152. (Impact factor 1.2 in 2009). (WoS)
- Lim SY, Wadia P, Wenning GK, Lang AE. Clinically- probable MSA associated with myotonic dystrophy type 2. Movement Disorders 2009;24(9):1407-1409. (Impact factor 4.0 in 2009). (WoS)
- Lim SY, Fox SH, Lang AE. Overview of the extra-nigral aspects of Parkinson disease. Archives of Neurology 2009;66(2):167-172. (Impact factor 6.3 in 2009). (WoS)
- Lim SY, Mason WP, Young NP, Chen R, Bower JH, McKeon A, Pittock SJ, Lang AE. Polymyoclonus, laryngospasm, and cerebellar ataxia associated with adenocarcinoma and multiple neural cation channel autoantibodies. Archives of Neurology 2009;66(10):1285-1287. (Impact factor 6.3 in 2009). (WoS)
- Lim SY, Fox SH, Lang AE. Parkinson Disease: Extranigral, Multisystem, and Alpha-Synuclein "Plus" - Reply. Archives of Neurology 2009;66(7):915-916. (Impact factor 6.3 in 2009). (WoS)
- Lim SY, Thevathasan W, Gonzales M, Mitchell PJ, Evans AH. Vasogenic oedema with no mass lesion. Journal of Clinical Neuroscience 2008;15(9):1048,1075-1076. (Impact factor 1.2 in 2009). (WoS)
- Lim SY, Fox SH. An update on the management of Parkinson's disease. Geriatrics and Aging 2008;11 (4):215-222. (SCOPUS)
- Lim SY, Evans AH, Miyasaki JM. Impulse control and related disorders in Parkinson's disease: Review. Annals of the New York Academy of Sciences (The Year in Neurology 2008) 2008;1142:85-107. (Impact factor 2.67 in 2009). (WoS)
- Lim SY, Evans AH. A young woman with slowly- progressive generalized dystonia. Journal of Clinical Neuroscience 2008;15(1):66,94. (Impact factor 1.2 in 2009). (WoS)
- Lim SY, Farrell MJ, Gibson SJ, Helme RD, Lang AE, Evans AH. Do dyskinesia and pain share common pathophysiological mechanisms in Parkinson disease? Movement Disorders 2008;23(12):1689-1695. (Impact factor 4.0 in 2009). (WoS)
- Lim SY. Flaccid quadriplegia. Journal of Clinical Neuroscience 2006;13(4):466,507. (Impact factor 1.2 in 2009). (WoS)
- Lim SY. Oro-facial dyskinesias and obsessive compulsive disorder. Journal of Clinical Neuroscience 2006;13(10):1018,1070. (Impact factor 1.2 in 2009). (WoS)
- Lim SY, Tan AH. Management of autonomic dysfunction in Parkinson s disease. In: Galvez-Jimenez N, Fernandez H, Espay A, Fox SH. Parkinson Disease: Current & Future Therapeutics & Clinical Trials. Cambridge: Cambridge University Press, 2016, pp. 93-110.
- Lim SY, Moro E, Tan AH, Lang AE. Non-motor symptoms of Parkinson's disease and the effects of deep brain stimulation. In: Chaudhuri KR, Tolosa E, Schapira A, Poewe W, editors. Non-Motor Symptoms of Parkinson's Disease (2nd ed). Oxford: Oxford University Press 2014, pp. 394-419.
- Lim SY, Evans AH. Chapter 29: Pain and paresthesia in Parkinson s disease. In: Olanow CW, Stocchi F, Lang AE, editors. Parkinson s disease: Non-motor and non-dopaminergic features. Oxford: Blackwell Publishing, 2011, pp. 317-334.
- Lim SY, Moro E, Lang AE. Chapter 27: Non-motor symptoms of Parkinson's disease and the effects of deep brain stimulation. In: Chaudhuri KR, Tolosa E, Schapira A, Poewe W, editors. Non-Motor Symptoms of Parkinson's Disease. Oxford: Oxford University Press, 2009, pp. 339-352.
- Lim Shen-Yang (Lead Author), Norlinah Mohd. Ibrahim, Santhi Datuk Puvanarajah, Lee Moon Keen, Chee Kok Yoon, Shanti Viswanathan, Tan Ai Huey, Chris Chong Kang Tird, Kamal Azrin Bin Abdullah @ Kalai Arasu A/L Muthusamy. 2012 Consensus Guidelines for the Treatment of Parkinson's Disease. (A treatment guidelines booklet, distributed for free to doctors, under the auspices of the Malaysian Movement Disorders Council).
- Lim Shen-Yang, Santhi Datuk Puvanarajah, Norlinah Mohd. Ibrahim. Parkinson's Disease: Information for People Living with Parkinson's. (An information booklet distributed for free, under the auspices of the Malaysian Parkinson's Disease Association and also available to download from the MPDA website).
(Contribution to Society),(Duration),(Level)
- Invited Expert on national radio ("Health & Living" on Business FM with Meera Sivasothy and Dr. George Lee; Topic: Parkinson's disease, exercise and dancing), 4.15 pm (Kuala Lumpur), 2022
- Training of the first Parkinson Disease nurse specialist in Malaysia (Puan Yuslina binti Yusoff), 2022
- Talk to / discussion with patients with Parkinson Disease and caregivers. Malaysian Parkinson Disease Association meeting (Ipoh), 2022
- Invited speaker on national radio (The Bigger Picture on Business FM with Meera Sivasothy; Topic: Parkinson disease with an emphasis on non-motor symptoms), 4.00-4.40 pm (Kuala Lumpur), 2022
- Talk to / discussion with patients with Parkinson Disease and caregivers (Update on Parkinson Disease). Terengganu Parkinson Disease Association meeting (Kuala Terengganu), 2022
- Talk to / discussion with patients with Parkinson Disease and caregivers (Update on Parkinson Disease). Public Forum organised by the Malaysian Parkinson s Disease Association & Jeffrey Cheah School of Medicine and Health Sciences, Monash University (Bandar Sunway), 2022
- Featured in the Star Newspaper ("About Parkinson's: Here are 10 important facts you need to know about Parkinson's disease"), page T13, 2022
- Featured in the Star Newspaper ("Attention to detail: How to get the most out of your visit to the doctor's"), page T13, 2022
- Featured in the Sin Chew Daily Newspaper (Metro Edition) ("Parkinson Disease"), page 24, 2022
- Featured in the Star Newspaper ("Health Concerns"), page T15, 2022
- Featured in the Star Newspaper ("Common ills: Most people still do not know what neurologists do"), page T14, 2022
- Quoted in the Star Newspaper ("A Brighter Future"), page T15, 2022
- Talk to / discussion with patients with Parkinson Disease and caregivers (Neuropsychiatric Aspects of Parkinson Disease). Malaysian Parkinson Disease Association (MPDA) & Petaling Jaya City Council Public forum on Parkinson Disease (Petaling Jaya), 2022
- Invited speaker on national television (The Breakfast Show on ntv7; Topic: Parkinson disease (Kuala Lumpur), 2022
- Invited speaker on national radio (The Lite Breakfast on LiteFM with Zak and Sara; Topic: Parkinson disease), 7-9 am (Kuala Lumpur), 2022
- Talk to / discussion with patients with Parkinson Disease and caregivers (Current Treatment Approaches in Parkinson Disease). Malaysian Parkinson Disease Association meeting (Kuala Lumpur), 2022
- Medical Advisor, Malaysian Parkinson Disease Association, 31/07/2009 to 31/12/2021
- Medical Advisor to the Malaysian Parkinson Disease Association, 31/07/2009 to 31/12/2014
(Activity),(Duration),(Category)
(Name of Award/Stewardship),(Awarding Institution),(Year Awarded),(Type of Award)
- Travel Grant (to my junior colleague Dr. Tan Ai Huey), Montreal, Canada. (Poster was also selected for presentation), 3rd World Parkinson Congress, 2013 (RESEARCH)
- Junior Investigator Travel Awards (to my junior colleagues, Dr. Tan Ai Huey and Ms. Aroma Agape), 17th International Congress of Parkinson's Disease and Movement Disorders, Sydney, Australia, 2013 (RESEARCH)
- Elected Co-Chair, International Movement Disorder Society (Asian & Oceanian Section) Education Committee, 2013 (RESEARCH)
- Travel Bursary (to my junior colleague Dr. Tan Ai Huey), Vienna, Austria, 21st World Congress of Neurology, 2013 (RESEARCH)
- Vocational Award for "Exemplary service & dedication in the field of Parkinson's & Movement Disorders", Rotary Club, Metro KL, 2012 (OTHERS)
- High-Impact Research (HIR) Grant, University of Malaya / Ministry of Higher Education, 2012 (RESEARCH)
- Invitation to deliver a Plenary Lecture, 16th International Congress of Parkinson's Disease and Movement Disorders, Dublin, Ireland, 2012 (RESEARCH)
- High-Impact Research (HIR) Grant, University of Malaya / Ministry of Higher Education, 2011 (RESEARCH)
- Visiting Professorship, Movement Disorder Society, 2011 (RESEARCH)
- Young Investigator Award for Best Publication, Malaysian Society of Neurosciences, 2011 (RESEARCH)
- Selected to represent Malaysia / Academy of Science at the Program for Young Physician Leaders, World Health Summit, Berlin, 2011 (RESEARCH)
- Invitation to deliver a Plenary Lecture, 15th International Congress of Parkinson's Disease and Movement Disorders, Toronto, Canada, 2011 (RESEARCH)
- Junior Investigator Travel Award (to my student, Ms. Tan Zi Kheng), 15th International Congress of Parkinson's Disease and Movement Disorders, Toronto, Canada, 2011 (RESEARCH)
- Elected Member of the Executive Committee, International Movement Disorder Society (Asian & Oceanian Section), 2011 (RESEARCH)
- CERTIFICATE OF EXCELLENT SERVICE, University of Malaya, 2011 (CERTIFICATE)
- Poster awarded 2nd prize, Malaysian Society of Neurosciences 21st Annual Scientific Meeting, 2010 (RESEARCH)
- Merit in Service Certificate (Sijil Perkhidmatan Cemerlang), University of Malaya, 2010 (RESEARCH)
- Poster selected for oral presentation, American Academy of Neurology 61st Annual Meeting, 2009 (RESEARCH)
- Member of the 4-strong team representing Malaysia that beat 13 other national teams to win the Tournament of the Minds, 19th World Congress of Neurology, 2009 (RESEARCH)
- Partial Fellowship, 18th annual Aspen course on Movement Disorders (awarded by Prof. Stanley Fahn), 2008 (RESEARCH)
- Edmond J. Safra Fellowship in Neurodegenerative Diseases and Doris Edwards Fellowship, Toronto Western Hospital / University of Toronto, 2008 (RESEARCH)
- Junior Investigator Travel Award, Movement Disorder Society, 2007 (RESEARCH)
- The Victor Hurley Medical Research Fund Grant-in-Aid, Royal Melbourne Hospital, 2006 (RESEARCH)
- Special Postgraduate Studentship, University of Melbourne (Centre for Neuroscience), 2006 (RESEARCH)
(Project title),(Organisation),(Duration),(Role),(Level)
- CHDI Foundation, the largest funder of Huntington disease research worldwide, (Princeton, USA), 01/05/2012 to 01/05/2013 (International)
(Title),(Event),(Date Presented),(Organiser),(Level)