Curriculum Vitae

DR. CHEW KEE SEANG

Medical Lecturer
  • Department of Paediatrics
    Faculty of Medicine
  • 0379496347

AREAS OF EXPERTISE

  • CLINICAL NUTRITION
    Paediatric Nutrition
  • GASTROENTEROLOGY
    Paediatric Gastroenterology, Hepatology
  • PAEDIATRICS
    General Paediatrics, Pediatrics

ACADEMIC QUALIFICATION

  • MRCPCH, (Pediatrik)
    Royal College of Paediatrics and Child Health
  • M.PAE, (Paediatric)
    Universiti Malaya (UM)
  • MBBS, (Medicine and Surgery)
    Universiti Malaya (UM)

ADMINISTRATIVE DUTIES

  • Coordinator
    01 Jan 2021 - 31 Dec 2021 (Department of Paediatrics, Faculty of Medicine)
  • Coordinator
    01 Jan 2021 - 31 Dec 2021 (Department of Paediatrics, Faculty of Medicine)
  • Coordinator
    01 Jan 2021 - 31 Dec 2021 (Department of Paediatrics, Faculty of Medicine)
  • Quality Manager
    01 Jan 2021 - 31 Dec 2021 (Department of Paediatrics, Faculty of Medicine)
  • UMMC Clinical Quality Assurance Committee
    01 Jan 2021 - 31 Dec 2021 (Department of Paediatrics, Faculty of Medicine)

MEMBERSHIPS

  • MALAYSIAN SOCIETY OF PAEDIATRIC GASTROENTEROLOGY, HEPATOLOGY AND NUTRITION-ASSISTANT SECRETARY, ASSISTANT SECRETARY
    Since 2022 (National)
  • MALAYSIAN PAEDIATRIC ASSOCIATION - LIFE MEMBER, MEMBER
    Since 2018 (National)
  • MALAYSIAN PAEDIATRIC ASSOCIATION, MEMBER
    Since 2017 (National)
  • ACADEMY OF MEDICINE OF MALAYSIA - ORDINARY MEMBER, MEMBER
    2023 to 2023 (National)
  • ASIAN PAN-PACIFIC SOCIETY FOR PEDIATRIC GASTROENTEROLOGY HEPATOLOGY AND NUTRITION-ORDINARY MEMBER, MEMBER
    2021 to 2023 (International)
  • ASIAN PAN-PACIFIC SOCIETY FOR PEDIATRIC GASTROENTEROLOGY HEPATOLOGY AND NUTRITION-ORDINARY MEMBER, MEMBER
    2020 to 2023 (International)
  • MEMBERSHIP OF THE ROYAL COLLEGE OF PAEDIATRICS AND CHILD HEALTH (MRCPCH), MEMBER
    2019 to 2023 (International)
  • ASIAN PAN-PACIFIC SOCIETY FOR PAEDIATRIC GASTROENTEROLOGY, HEPATOLOGY AND NUTRITION, MEMBER
    2019 to 2023 (International)
  • MALAYSIA MEDICAL ASSOCIATION, MEMBER
    2018 to 2022 (National)
  • MEDICAL PROTECTION SOCIETY, MEMBER
    2017 to 2022 (International)

AWARD AND STEWARDSHIP

  • CERTIFICATE OF EXCELLENT SERVICE
    University of Malaya, 2023 (University)
  • Young Investigator Award
    WCPGHAN, 2021 (International)
  • Excellence service award
    University Malaya Medical Centre, 2020 (University)

PUBLICATIONS

Article in Journal
WoS
  1. Ranai, Norashikin Mohd; Chew, Kee Seang; Lim, Wei Kang; Fong, Choong Yi; Li, Limin; Ng, Ruey Terng; Lee, Way Seah (2023). Cerebral venous sinus thrombosis in young children with inflammatory bowel disease: A report of two cases, NEUROLOGY ASIA. 28(3), 781-783. doi:10.54029/2023nnk
  2. Simovic, Isidora; Hilmi, Ida; Ng, Ruey Terng; Chew, Kee Seang; Wong, Shin Yee; Lee, Way Seah; Riordan, Stephen; Castano-Rodriguez, Natalia (2023). ATG16L1 rs2241880/T300A increases susceptibility to perianal Crohn's disease: An updated meta-analysis on inflammatory bowel disease risk and clinical outcomes, UNITED EUROPEAN GASTROENTEROLOGY JOURNAL. . doi:10.1002/ueg2.12477
  3. Huang, James Guoxian; Wong, Yoko Kin Yoke; Chew, Kee Seang; Tanpowpong, Pornthep; Calixto Mercado, Karen Sophia; Reodica, Almida; Rajindrajith, Shaman; Chang, Kai-Chi; Ni, Yen-Hsuan; Treepongkaruna, Suporn; Lee, Way-Seah; Aw, Marion Margaret (2022). Epidemiological characteristics of Asian children with inflammatory bowel disease at diagnosis: Insights from an Asian-Pacific multi-centre registry network, WORLD JOURNAL OF GASTROENTEROLOGY. 28(17), 1830-1844. doi:10.3748/wjg.v28.i17.1830
  4. Khoo, Xin-Hui; Wong, Shin Yee; Ibrahim, Nik Razima Wan; Ng, Ruey Terng; Chew, Kee Seang; Lee, Way Seah; Wong, Zhi Qin; Raja Ali, Raja Affend; Shahrani, Shahreedhan; Leow, Alex Hwong-Ruey; Hilmi, Ida Normiha (2022). Nudix Hydroxylase 15 Mutations Strongly Predict Thiopurine-Induced Leukopenia Across Different Asian Ethnicities: Implications for Screening in a Diverse Population, FRONTIERS IN MEDICINE. 9. doi:10.3389/fmed.2022.880937
  5. Lee, Gin W.; Chew, Kee S.; Wong, Sean Y.; Chong, Sze Y.; Ong, Sik Y.; Lee, Way S. (2022). Quality of life in Malaysian children with inflammatory bowel disease: An understudied population, JOURNAL OF PAEDIATRICS AND CHILD HEALTH. . doi:10.1111/jpc.16130
  6. Lee, Way S.; Song, Zhi L.; Wong, Sean Y.; Gan, Chai W.; Koay, Zhong L.; Em, Jun M.; Chong, Sze Y.; Lim, Chooi B.; Wong, Shin Y.; Chew, Kee S.; Kam, Choy C. (2022). Environmental risk factors for inflammatory bowel disease: A case control study in Southeast Asian children, JOURNAL OF PAEDIATRICS AND CHILD HEALTH. . doi:10.1111/jpc.15830
  7. Lee, Way Seah; Chew, Kee Seang (2022). Gastroesophageal reflux disease in Asian infants: Similar condition, different perceptions, ANNALS ACADEMY OF MEDICINE SINGAPORE. 51(5), 259-260. doi:10.47102/annals-acadmedsg.2022128
  8. Luu, Laurence Don Wai; Popple, Georgia; Tsang, Samuel Pok Wei; Vinasco, Karla; Hilmi, Ida; Ng, Ruey Terng; Chew, Kee Seang; Wong, Shin Yee; Riordan, Stephen; Lee, Way Seah; Mitchell, Hazel M.; Kaakoush, Nadeem O.; Castano-Rodriguez, Natalia (2022). Genetic variants involved in innate immunity modulate the risk of inflammatory bowel diseases in an understudied Malaysian population, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. . doi:10.1111/jgh.15752
  9. Ng, Ruey Terng; Chew, Kee Seang; Choong, Chee Liang; Song, Zhi Liang; Teh, Jane Kimm Lii; Koay, Zhong Ling; Wong, Shin Yee; Kam, Choy Chen; Ranai, Norashikin Binti Mohd; Lee, Way Seah (2022). Etiology, outcome and prognostic indicators of acute liver failure in Asian children, HEPATOLOGY INTERNATIONAL. 16(6), 1390-1397. doi:10.1007/s12072-022-10417-5
  10. Chan, K. J., Song, Z. L., Chew, K. S., Ng, R. T., Taib, S. H. M., & Lee, W. S. (2021). Exclusive enteral nutrition is effective and feasible as primary induction and re-induction therapy in Asian children with Crohn's disease. Journal of Paediatrics and Child Health, 57(2), 239-245. doi: 10.1111/jpc.15184
  11. Chew, K. S., Em, J. M., Koay, Z. L., Jalaludin, M. Y., Ng, R. T., Lum, L. C. S., & Lee, W. S. (2021). Low prevalence of infantile functional gastrointestinal disorders (FGIDs) in a multi-ethnic Asian population. Pediatrics and Neonatology, 62(1), 49-54. doi: 10.1016/j.pedneo.2020.08.009
  12. Lee, W. S., Song, Z. L., Em, J. M., Chew, K. S., & Ng, R. T. (2021). Role of primary prophylaxis in preventing variceal bleeding in children with gastroesophageal varices. Pediatrics and Neonatology, 62(3), 249-257. doi: 10.1016/j.pedneo.2021.01.002
  13. Nandakumal, G., Ismail, F., Mohamad, N. F., Lott, P. W., Chew, K. S., Ab Rahman, S., & Singh, S. (2021). A Rare Case of von Willebrand Disease Presenting as Hemolacria and Literature Review. Journal of Pediatric Hematology Oncology, 43(3), 101-103. doi: 10.1097/mph.0000000000002077
  14. Ooi, C. J.; Nathan, A. M.; Eg, K. P.; Chew, K. S.; Ng, R. T.; Lee, W. S.; Boey, C.; de Bruyne, J. A. (2021). Cost Analysis of Children with Cystic Fibrosis versus Inflammatory Bowel Disease in a Developing Country, PEDIATRIC PULMONOLOGY. 56, S121-S122
  15. Ariffin, Hany; Chew, Kee Seang; Jawin, Vida; Thavagnanam, Surendran (2020). T-cell-replete haploidentical bone marrow transplantation for X-linked severe combined immunodeficiency, SINGAPORE MEDICAL JOURNAL. 61(5), 285-286. doi:10.11622/smedj.2018101
  16. Lee, W. S., Chew, K. S., Ng, R. T., Kasmi, K. E., Sokol, R. J. (2020). Intestinal failure-associated liver disease (IFALD): insights into pathogenesis and advances in management. Hepatology International, 14(3), 305-316. doi: 10.1007/s12072-020-10048-8
  17. Lee, Way S.; Chew, Kee S.; Ng, Ruey T.; Kasmi, Karim El; Sokol, Ronald J. (2020). Intestinal failure-associated liver disease (IFALD): insights into pathogenesis and advances in management, HEPATOLOGY INTERNATIONAL. 14(3), 305-316. doi:10.1007/s12072-020-10048-8
  18. Lee, W. S., Tee, C. W., Tan, A. G. S., Wong, S. Y., Chew, K. S., Cheang, H. K., . . . Aw, M. M. (2019). Parental concern of feeding difficulty predicts poor growth status in their child. Pediatrics and Neonatology, 60(6), 676-683. doi:10.1016/j.pedneo.2019.04.004
  19. Cheang, H. K., Wong, H. T., Ho, S. C., Chew, K. S., Lee, W. S. (2013). Immune response in infants after universal hepatitis B vaccination: a community-based study in Malaysia, Singapore Medical Journal. 54(4), 224-226
  20. Chew, K. S., Oon, L. K., Lee, R. A., Lim, K. S., Tan, C. T. (2010). Withdrawal response in healthy adults, Neurology Asia. 15(2), 159-165
Chapter in Books
  1. 3.Chew KS. Nutritional Assessment. (2021). In: Lee WS, Chong SY, Ong SY. Gastroenterology, Hepatology And nutrition in children: A survival guide. UMPress. 1st Ed. 2021.
  2. Chew KS. Feeding difficulty. (2021). In: Lee WS, Chong SY, Ong SY. Gastroenterology, Hepatology And nutrition in children: A survival guide. UMPress. 1st Ed. 2021.
  3. Lee WS. (2021). Cow's milk protein allergy. In: Lee WS, Ong SY, Chong SY (Eds), Paediatric Gastroenterology, Hepatology and Nutrition: A Survival Guide. Kuala Lumpur; University Malaya Press
  4. Chew KS. Fluids, Electrolytes and Acid base balance. (2019) In: Lee WS, Tay CG, Lum SH. Textbook of Paediatrics and Child Health. UMPress. 1st Ed. 2019

RESEARCH INTEREST

  • Functional gastrointestinal disorder in children (FGID, children)
  • Liver Transplant in children (Liver transplant)

RESEARCH PROJECT

National
  1. 2023 - 2026, Fundamental Research Grant Scheme (FRGS)
    Identification Of Risk Factors And The Development Of A Novel Exposome Risk Score For Inflammatory Bowel Disease In Malaysia ( Co-Researcher)
  2. 2023 - 2025, University Grant
    Developing an Evidence-Based, Malaysian Food-Based Dietary Guide for the Treatment of Inflammatory Bowel Disease in Children and Adolescents ( Co-Inventor)
  3. 2020 - 2024, Albireo AB
    A Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Odevixibat (A4250) in Children with Biliary Atresia Who Have Undergone a Kasai Hepatoportoenterostomy (Biliary Atresia Odevixibat Liver Disease [BOLD]) ( Co-Researcher)
  4. 2022 - 2024, Albireo AB
    An Open Label Study to Evaluate the Long-term Safety and Efficacy of Odevixibat (A4250) in Patients with Alagille Syndrome (ASSERT-EXT) ( Co-Researcher)
  5. 2020 - 2024, ALBIREO AB
    A Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Odevixibat (A4250) in Children with Biliary Atresia Who Have Undergone a Kasai Hepatoportoenterostomy (BOLD) ( Co-Researcher)
  6. 2021 - 2022, ALBERIO PHARMA INC
    A Phase 3 Double-blind, Randomized, Placebo-controlled Study of the Safety and Efficacy of Odevixibat (A4250) in Patients with Alagille Syndrome (ASSERT) ( Co-Researcher)
Private
  1. 2022 - 2023, Universiti Tunku Abdul Rahman Research Fund
    Gut microbiota and Inflammatory Bowel Disease in Asian children, Universiti Tunku Abdul Rahman (UTAR) ( Co-Researcher)
International
  1. 2018 - 2030
    Asian Pediatrics Inflammatory Bowel Disease Research Network, National University of Singapore ( Co-Researcher)
  2. 2022 - 2025, Albireo AB
    An Open-label Extension Study to Evaluate Long-term Efficacy and Safety of Odevixibat (A4250) in Children with Biliary Atresia (BOLD-EXT) ( Co-Researcher)
  3. 2020 - 2024, Albireo
    A Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Odevixibat (A4250) in Children with Biliary Atresia Who Have Undergone the Kasai Hepatoportoenterostomy (BOLD), Pittsburgh University, Pittsburgh ( Co-Researcher)

PAPER PRESENTED

PLENARY SPEAKER
  1. Pediatric IBD: Approach to a case of early onset IBD, AIG IBD Summit, AIG (International) (07 Apr 2023 - 09 Apr 2023)
ORAL PRESENTER
  1. Resources and Management Practice of Pediatric IBD in Asia Pacific Region: a web-based survey, The 16th Asian Pan-Pacific Congress for PGHAN, APPSPGHAN (International) (05 Oct 2023 - 08 Oct 2023)

ACADEMIC/PROF. SERVICES

Evaluation
  1. (2022) Assessor: Development of Whole Gastrointestinal Transit Scintigraphy Imaging Protocol in Paediatric Patients Using Sm-153-Radiolabelled, University, (Internal Examiner)
Media appearance
  1. (2023) 8tv Living Delights Show Appearance: What to Do During Accidental Ingestion of Small Objects?, National, (Interview)

SUPERVISION

Postgraduate Student
Master
  1. (2022) Effect of Enteral Nutrition on Gut Microbiome in Malaysian Children with Crohn's Disease, Linah Wetthasinghe (Universiti Tunku Abdul Rahman (Utar))
  2. (2020) -, MUHAMMAD SYAZWAN MOHD NOR
  3. (2019) -, MUKMIN BIN MOHD KHAIRI
  4. (2018) Epidemiology and Factors Affecting Outcomes in Paediatric Inflammatory Bowel Disease in Malaysia, NORUL HUDA BINTI NAZIR
  5. (2017) Paediatric Liver Transplant ? Outcome and Complication, SHARIFAH FAIRUS BINTI BOHARI
Under Graduate Students
  1. (2023) MRCPCH training supervisor