Curriculum Vitae

DR. KONG BOON HONG

Senior Lecturer
  • Department of Molecular Medicine
    Faculty of Medicine
  • 03-79674718

AREAS OF EXPERTISE

  • TRADITIONAL MEDICINE AND NATURAL PRODUCTS
    Biopharmaceuticals and Toxicological Assessment of Medicinal Mushrooms
  • TRADITIONAL MEDICINE AND NATURAL PRODUCTS
    Bioactive Components from Medicinal Mushrooms
  • MOLECULAR MICROBIOLOGY
    Epidemiology, Mechanisms of Drug Resistance
  • BACTERIOLOGY
    Identification, Antimicrobial Resistance

ACADEMIC QUALIFICATION

  • PhD, (Molecular Medicine)
    Universiti Malaya (UM)
  • MSc, (Medical Microbiology)
    Universiti Malaya (UM)
  • BSc, (Microbiology)
    Universiti Malaya (UM)

MEMBERSHIPS

  • ORGANIZATION FOR WOMEN IN SCIENCE FOR THE DEVELOPING WORLD (OWSD), MEMBER
    Since 2019 (International)
  • MALAYSIAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY (MSBMB), MEMBER
    2023 to 2023 (National)

PUBLICATIONS

Article in Journal
WoS
  1. Ng, Min Jia; Kong, Boon Hong; Teoh, Kean Hooi; Yap, Yeannie Hui-Yeng; Ng, Szu Ting; Tan, Chon Seng; Razif, Muhammad Fazril Mohamad; Fung, Shin Yee (2023). In vivo anti-tumor activity of Lignosus rhinocerus TM02 (R) using a MCF7-xenograft NCr nude mice model, JOURNAL OF ETHNOPHARMACOLOGY. 304. doi:10.1016/j.jep.2022.115957
  2. Ng, Min Jia; Razif, Muhammad Fazril Mohamad; Kong, Boon Hong; Ng, Szu Ting; Tan, Chon Seng; Yap, Hui-Yeng Yeannie; Fung, Shin Yee (2023). The genome of Lignosus tigris: Uncovering its hidden nutraceutical potential, SOUTH AFRICAN JOURNAL OF BOTANY. 154, 108-119. doi:10.1016/j.sajb.2023.01.019
  3. Yap, Hui-Yeng Y.; Rosli, Mohammad Farhan Ariffeen; Tan, Soon-Hao; Kong, Boon-Hong; Fung, Shin-Yee (2023). The Wound Healing Potential of Lignosus rhinocerus and Other Ethno-myco Wound Healing Agents, MYCOBIOLOGY. 51(1), 1-15. doi:10.1080/12298093.2022.2164641
  4. Pang, Li-Yin; Lee, Mei-Kee; Kong, Boon Hong; Fung, Shin-Yee; Ng, Szu Ting; Tan, Chon Seng; Then, Sue-Mian; Lim, Kuan-Hon; Roberts, Richard; Ting, Kang-Nee (2022). Chinese Caterpillar Mushroom, Ophiocordyceps sinensis (Ascomycota), Cold-Water Extract Relaxes the Rat Isolated Bladder, INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS. 24(3), 1-14
  5. Yap, Hui Yeng Yeannie; Kong, Boon Hong; Yap, Chee Sum Alvin; Ong, Kien Chai; Zain, Rosnah Binti; Tan, Soon Hao; Zaini, Zuraiza Mohamad; Ng, Szu Ting; Tan, Chon Seng; Fung, Shin Yee (2022). Immunomodulatory Effect and an Intervention of TNF Signalling Leading to Apoptotic and Cell Cycle Arrest on ORL-204 Oral Cancer Cells by Tiger Milk Mushroom, Lignosus rhinocerus, FOOD TECHNOLOGY AND BIOTECHNOLOGY. 60(1), 80-88. doi:10.17113/ftb.60.01.22.7296
  6. Kong, B. H., & Fung, S. Y. (2021). Longitudinal Assessment of the Tiger Milk Medicinal Mushroom, Lignosus rhinocerus (Agaricomycetes), Sclerotium Cultivar: Uniformity of Bioactive Components. International Journal of Medicinal Mushrooms, 23(10), 61-68. doi: 10.1615/IntJMedMushrooms.2021040120
  7. Kong, B. H., Yap, C. S. A., Razif, M. F. M., Ng, S. T., Tan, C. S., & Fung, S. Y. (2021). Antioxidant and Cytotoxic Effects and Identification of Ophiocordyceps sinensis Bioactive Proteins Using Shotgun Proteomic Analysis. Food Technology and Biotechnology, 59(2), 201-208. doi: 10.17113/ftb.59.02.21.7151
  8. Kong, B. H., Teoh, K. H., Tan, N. H., Tan, C. S., Ng, S. T., & Fung, S. Y. (2020). Proteins from Lignosus tigris with selective apoptotic cytotoxicity towards MCF7 cell line and suppresses MCF7-xenograft tumor growth. PeerJ, 8, 21. doi: 10.7717/peerj.9650
  9. Cheong, P. C. H., Yong, Y. S., Fatima, A., Ng, S. T., Tan, C. S., Kong, B. H., . . . Fung, S. Y. (2019). Cloning, overexpression, purification, and modeling of a lectin (Rhinocelectin) with antiproliferative activity from Tiger Milk Mushroom, Lignosus rhinocerus. Iubmb Life, 71(10), 1579-1594. doi:10.1002/iub.2101
  10. Fung, Shin Yee; Tan, Nget Hong; Kong, Boon Hong; Lee, Sook Shien; Tan, Yee Shin; Sabaratnam, Vikineswary (2017). Acute Toxicity Study and the In Vitro Cytotoxicity of a Black Lingzhi Medicinal Mushroom, Amauroderma rugosum (Agaricomycetes), from Malaysia, INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS. 19(12), 1093-1099. doi:10.1615/IntJMedMushrooms.2017024550
  11. Yap, Hui-Yeng Yeannie; Muria-Gonzalez, Mariano Jordi; Kong, Boon-Hong; Stubbs, Keith A.; Tan, Chon-Seng; Ng, Szu-Ting; Tan, Nget-Hong; Solomon, Peter S.; Fung, Shin-Yee; Chooi, Yit-Heng (2017). Heterologous expression of cytotoxic sesquiterpenoids from the medicinal mushroom Lignosus rhinocerotis in yeast, MICROBIAL CELL FACTORIES. 16. doi:10.1186/s12934-017-0713-x
  12. Kong, Boon-Hong; Tan, Nget-Hong; Fung, Shin-Yee; Pailoor, Jayalakshmi (2016). Sub-Acute Toxicity Study of Tiger Milk Mushroom Lignosus tigris Chon S. Tan Cultivar E Sclerotium in Sprague Dawley Rats, FRONTIERS IN PHARMACOLOGY. 7. doi:10.3389/fphar.2016.00246
  13. Kong, Boon-Hong; Tan, Nget-Hong; Fung, Shin-Yee; Pailoor, Jayalakshmi; Tan, Chon-Seng; Ng, Szu-Ting (2016). Nutritional composition, antioxidant properties, and toxicology evaluation of the sclerotium of Tiger Milk Mushroom Lignosus tigris cultivar E, NUTRITION RESEARCH. 36(2), 174-183. doi:10.1016/j.nutres.2015.10.004
  14. Chai, Lay Ching; Kong, Boon Hong; Elemfareji, Omar Ismail; Thong, Kwai Lin (2012). Variable Carbon Catabolism among Salmonella enterica Serovar Typhi Isolates, PLOS ONE. 7(5). doi:10.1371/journal.pone.0036201
  15. Ho, Wing Sze; Balan, Ganeswrie; Puthucheary, Savithiri; Kong, Boon Hong; Lim, King Ting; Tan, Lai Kuan; Koh, Xiu Pei; Yeo, Chew Chieng; Thong, Kwai Lin (2012). Prevalence and Characterization of Multidrug-Resistant and Extended-Spectrum Beta-Lactamase-Producing Escherichia coli from Pediatric Wards of a Malaysian Hospital, MICROBIAL DRUG RESISTANCE. 18(4), 408-416. doi:10.1089/mdr.2011.0222
  16. Kong, B. H.; Hanifah, Y. A.; Yusof, M. Y.; Thong, K. L. (2011). Application of amplified ribosomal DNA restriction analysis in identification of Acinetobacter baumannii from a Tertiary Teaching Hospital, Malaysia, TROPICAL BIOMEDICINE. 28(3), 563-568
  17. Kong, Boon Hong; Abu Hanifah, Yasmin; Yusof, Mohd Yasim Mohd; Thong, Kwai Lin (2011). Antimicrobial Susceptibility Profiling and Genomic Diversity of Multidrug-Resistant Acinetobacter baumannii Isolates from a Teaching Hospital in Malaysia, JAPANESE JOURNAL OF INFECTIOUS DISEASES. 64(4), 337-340
Scopus
  1. Goh N.-Y., Yap Y.H.-Y., Ng C.L., Kong B.-H., Ng S.-T., Tan C.-S., Mohamad Razif M.F., Fung S.-Y. (2024). Water-soluble compounds from Lignosus rhinocerus TM02 (xLr ) modulate ACE2 activity and inhibit its interaction with SARS-CoV-2 spike-protein, Food Bioscience. 59. doi:10.1016/j.fbio.2024.104232
  2. Ng M.J., Mohamad Razif M.F., Kong B.H., Yap H.-Y.Y., Ng S.T., Tan C.S., Fung S.-Y. (2024). RNA-seq transcriptome and pathway analysis of the medicinal mushroom Lignosus tigris (Polyporaceae) offer insights into its bioactive compounds with anticancer and antioxidant potential, Journal of Ethnopharmacology. 328. doi:10.1016/j.jep.2024.118073
  3. Kong B.H., Rumiyati R., Razif M.F.M., Fung S.Y. (2022). EVALUATION OF CHEMICAL COMPOUNDS FOUND IN Volvariella volvacea FROM RURAL SEDAYU, YOGYAKARTA, INDONESIA, Malaysian Journal of Biochemistry and Molecular Biology. 25(2), 37-42
  4. Razif M.F.M., Kong B.-H., Yee Y.-K., Zulkapli N., Nik Ampuan N.N.A., Fung S.-Y. (2022). FERMENTED Morinda citrifolia LINN JUICE HAS REDUCED ANTIOXIDANT CAPACITY AND DEMONSTRATES CYTOTOXICITY TOWARDS HUMAN BREAST CANCER CELLS, Malaysian Journal of Biochemistry and Molecular Biology. 25(1), 51-57
Chapter in Books
  1. Hui-Yeng Yeannie Yap, Boon Hong Kong and Shin Yee Fung (2022). Bioactive Properties of Malaysian Medicinal Mushrooms Lignosus spp. In: Fungal Biotechnology: Prospects and Avenues. (Eds: Kandikere R. Sridhar, Sunil K. Deshmukh) In Press

RESEARCH PROJECT

National
  1. 2022 - 2025, Fundamental Research Grant Scheme (FRGS)
    Isolation, Characterization And 3d Structure Studies Of A Novel Antineoplastic Deoxyribonuclease-like Protein From The Medicinal Fungi, Lignosus Tigris ( Co-Researcher)
  2. 2023 - 2025, Bantuan Khas Penyelidikan (BKP Special)
    Malaysia?s Functional Superfood, the Tiger Milk Mushroom TM02? as an Adjunct for the Maintenance of Optimal Health ( Co-Researcher)

SUPERVISION

Under Graduate Students
  1. (2023) Stage 3.1 Research Elective Posting
  2. (2023) Immunity following SARS CoV-2 boosters in individuals with hematological cancers