Curriculum Vitae

DR. KAMARIAH BINTI IBRAHIM

Senior Lecturer
  • Department of Biomedical Science
    Faculty of Medicine

AREAS OF EXPERTISE


  • CANCER BIOLOGY, MOLECULAR HAEMATOLOGY, BIOINFORMATICS

ACADEMIC QUALIFICATION


  • PHD, (Molecular Medicine)
    Universiti Kebangsaan Malaysia (UKM)
  • MSC, (Medical Science)
    Universiti Malaya (UM)
  • BSC, (Biomedical Science)
    Universiti Malaya (UM)

ADMINISTRATIVE DUTIES


  • Coordinator
    03 Aug 2023 - 03 Aug 2024 (Department of Biomedical Science, Faculty of Medicine)
  • Jawatankuasa Kurikulum Jabatan Sains Bioperubatan sesi 2023/2024
    01 Aug 2023 - 01 Aug 2024 (Department)
  • Jawatankuasa Buku Panduan Ijazah Dasar Jabatan Sains Bioperubatan 2023/24
    18 Apr 2023 - 18 Apr 2024 (Department)
  • MIC2023 Blood Transfusion Technology Course Coordinator
    27 Jan 2023 - 31 Dec 2023 (Department)
  • MIC2025 Bioinformatics for Biomedical Science Course Coordinator
    27 Jan 2023 - 31 Dec 2023 (Department)
  • MIC3006 Blood Transfusion Technology Course Coordinator
    27 Jan 2023 - 31 Dec 2023 (Department)
  • Coordinator
    15 Sep 2022 - 31 Mar 2023 (Department of Biomedical Science, Faculty of Medicine)
  • Coordinator
    27 Mar 2022 - 01 Oct 2022 (Department)
  • Course Coordinator
    27 Mar 2022 - 01 Oct 2022 (Department)
  • Course Coordinator
    25 Oct 2021 - 31 Jan 2022 (Department)
  • Acting Secretary
    01 Jan 2018 - 31 Dec 2021 (Department of Biomedical Science, Faculty of Medicine)
  • Acting Secretary
    20 Feb 2019 - 30 Dec 2020 (Department of Biomedical Science, Faculty of Medicine)
  • Coordinator
    01 Oct 2019 - 01 Mar 2020 (Department of Biomedical Science, Faculty of Medicine)
  • Coordinator
    10 Sep 2019 - 30 Jan 2020 (Department of Biomedical Science, Faculty of Medicine)
  • Coordinator
    01 Feb 2019 - 30 Jun 2019 (Department of Biomedical Science, Faculty of Medicine)
  • Ad-Hoc Committee Member, Devi Nallappan, Insulin-mimic actions of myricetin derivatives from Syzygium malaccense against adiposity, hyperglyceamia and their influence on gut microbiota
    19 Jun 2019 - 19 Jun 2019 (Department of Biomedical Science, Faculty of Medicine)
  • Coordinator
    05 Feb 2018 - 14 Jun 2018 (Department of Biomedical Science, Faculty of Medicine)

MEMBERSHIPS


  • MEMBER OF MALAYSIAN SOCIETY OF NEUROSCIENCES, MEMBER
    2023 to 2023 (National)
  • JOURNAL OF HEALTH AND TRANSLATIONAL MEDICINE, EDITORIAL MEMBER
    2019 to 2020 (University)
  • AMERICAN SOCIETY FOR MOLECULAR BIOLOGY AND BIOCHEMISTRY, ACTIVE MEMBER
    2019 to 2020 (International)
  • THAI JOURNAL OF PHARMACEUTICAL SCIENCES, # TJPS-2019-0152.R1, ARTICLE REVIEWER
    2019 to 2019 (International)

AWARD AND STEWARDSHIP


  • CERTIFICATE OF EXCELLENT SERVICE
    University of Malaya, 2023 (University)
  • Best Poster Award; Malaysian Symposium of Biomedical Science (MYSYMBIOS) (FYP student)
    Malaysian Biomedical Science Society, 2021 (National)
  • Best E-Poster Award, Hi-5 Retreat 2020 - V Symposium, Basic Neuroscience Council
    Malaysian Society of Neuroscience, 2020 (National)
  • Best Poster Award
    International Union for Biochemistry and Molecular Biology (IUBMB) & Malaysian Society for Biochemistry & Molecular Biology, 2019 (International)
  • 1st Prize; Young Investigator Award in Cancer; 2nd National Conference for Cancer Research in Conjunction with 6th Regional Conference on Molecular Medicine (RCMM)
    UKM, 2015 (International)
  • 3rd Prize for Three Minutes Thesis Competition, University Kebangsaan Malaysia
    UKM, 2015 (University)
  • Best Poster Presentation in Structural Biology; International Symposium & Workshop on Functional Genomics & Structural Biology
    UPM, 2014 (International)
  • 1st Prize; Young Investigator Award in Cancer; 1st National Conference for Cancer Research in Conjunction with 5th Regional Conference on Molecular Medicine (RCMM)
    UKM, 2013 (International)
  • UKM Postgraduate Mobility Travel Grant to participate and present at the Frontiers in Cancer Science Conference, Singapore
    UKM, 2012 (University)
  • Best Poster Presentation; 37th Malaysian Biochemistry and Molecular Biology Conference
    Malaysian Biochemistry and Molecular Biology Society, 2012 (National)
  • National Science Fellowship
    Ministry of Science, Technology and Innovation (MOSTI) , 2007 (Government)
  • MAKNA Cancer Research Award
    Majlis Kanser Nasional, 2006 (National)
  • Scholarship from the Malaysian Public Service Department
    Malaysian Public Service Department (JPA), 2002 (Government)

PUBLICATIONS


Article in Journal
WoS
  1. Azizan, Suha; Cheng, Kim Jun; Mohamed, Elsa Haniffah Mejia; Ibrahim, Kamariah; Faruqu, Farid Nazer; Vellasamy, Kumutha Malar; Khong, Tak Loon; Syafruddin, Saiful Effendi; Ibrahim, Zaridatul Aini (2024). Insights into the molecular mechanisms and signalling pathways of epithelial to mesenchymal transition (EMT) in colorectal cancer: A systematic review and bioinformatic analysis of gene expression, GENE. 896. doi:10.1016/j.gene.2023.148057
  2. Ibrahim, Kamariah; Ahmad-Annuar, Azlina (2022). COVID-19 pandemic: Lessons learned for undergraduate research training, BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION. . doi:10.1002/bmb.21665
  3. Rashid, Khairunnisa Abdul; Ibrahim, Kamariah; Wong, Jeannie Hsiu Ding; Ramli, Norlisah Mohd (2022). Lipid Alterations in Glioma: A Systematic Review, METABOLITES. 12(12). doi:10.3390/metabo12121280
  4. Zaidi, Noorzaileen Eileena; Shazali, Nur Aima Hafiza; Leow, Thean-Chor; Osman, Mohd Azuraidi; Ibrahim, Kamariah; Cheng, Wan-Hee; Lai, Kok-Song; Abd Rahman, Nik Mohd Afizan Nik (2022). CD36-Fatty Acid-Mediated Metastasis via the Bidirectional Interactions of Cancer Cells and Macrophages, CELLS. 11(22). doi:10.3390/cells11223556
  5. Ibrahim, K., Murad, N. A. A., Harun, R., & Jamal, R. (2020). Knockdown of Tousled-like kinase 1 inhibits survival of glioblastoma multiforme cells. International journal of molecular medicine, 46(2), 685-699. doi: 10.3892/ijmm.2020.4619
  6. Zaidi, N. E., Shazali, N. A. H., Chor, A. L. T., Osman, M. A., Ibrahim, K., Jaoi-Edward, M., Abd Rahman, N. (2019). Time-Lapse 2D Imaging of Phagocytic Activity in M1 Macrophage-4T1 Mouse Mammary Carcinoma Cells in Co-cultures. Jove-Journal of Visualized Experiments(154), 11. doi: 10.3791/60281
ESCI
  1. Kaur, Jesminder; Salehen, Nur'ain; Norazit, Anwar; Rahman, Amirah Abdul; Murad, Nor Azian Abdul; Abd Rahman, Nik Mohd Afizan Nik; Ibrahim, Kamariah (2022). Tumor Suppressive Effects of GAS5 in Cancer Cells, NON-CODING RNA. 8(3). doi:10.3390/ncrna8030039
  2. Zaidi, Noorzaileen Eileena; Shazali, Nur Aima Hafiza; Leow, Thean Chor; Osman, Mohd Azuraidi; Ibrahim, Kamariah; Abd Rahman, Nik Mohd Afizan Nik (2022). Crosstalk between fatty acid metabolism and tumour-associated macrophages in cancer progression, BIOMEDICINE-TAIWAN. 12(4), 9-19. doi:10.37796/2211-8039.1381
Scopus
  1. Vengidasan, L., Sin, C. S., Siong, C. K., & Ibrahim, K. (2021). Expression of telomeric repeat binding factor 2 (Terf2) in childhood acute lymphoblastic leukemia. Asia-Pacific Journal of Molecular Biology and Biotechnology, 29(2), 98-106. doi: 10.35118/apjmbb.2021.029.2.10
Others
  1. Che Mat, M.F., Mohamad Hanif, E.A., Abdul Murad, N.A., Ibrahim, K., Harun, R., and Jamal, R. Silencing of ZFP36L2 increases sensitivity to temozolomide through G2/M cell cycle arrest and BAX mediated apoptosis in GBM cells. Mol Biol Rep 48, 1493 1503 (2021). https://doi.org/10.1007/s11033-021-06144-z
  2. Chin TF, Ibrahim K, Thirunavakarasu T, et al. Nonclonal Chromosomal Aberrations in Childhood Leukemia Survivors. Fetal and Pediatric Pathology. 2018 Aug;37(4):243-253. DOI: 10.1080/15513815.2018.1492054.
  3. Ibrahim K, Abdullahi A.D, Abdul Murad N.A, Harun R, and Jamal R. (2018) In silico homology modelling and identification of Tousled-like kinase 1 inhibitors for glioblastoma therapy via high throughput virtual screening protein-ligand docking. Asia-Pacific Journal of Mol. Medicine, 8(1):1
  4. Ariffin H, Azanan MS, Abd Ghafar SS, et al. Young adult survivors of childhood acute lymphoblastic leukemia show evidence of chronic inflammation and cellular aging. Cancer. 2017;123(21):4207 4214. doi:10.1002/cncr.30857
  5. Che Mat, M.F., Abdul Murad, N.A., Ibrahim, K., Mohd Mokhtar, N., Wan Ngah, W.Z., Harun, R., & Jamal, R. (2016). Silencing of PROS1 induces apoptosis and inhibits migration and invasion of glioblastoma multiforme cells. International Journal of Oncology, 49, 2359-2366. https://doi.org/10.3892/ijo.2016.3755
  6. CHOONG, S.-S., ROSMANIZAM, S., IBRAHIM, K., GAN, G.-G. and ARIFFIN, H. (2011), Development of an algorithm of satellite markers for monitoring chimerism status in post-allogeneic haematopoietic stem cell transplantation patients. International Journal of Laboratory Hematology, 33: 182 186. doi:10.1111/j.1751-553X.2010.01264.x
  7. Daud, S. S., Ibrahim, K., Choong, S. S., Vengidasan, L., Chong, L. A., & Ariffin, H. (2010). Microfluidic chip-based assay for post-hematopoietic stem cell transplantation chimerism monitoring using polymorphic tandem repeat markers. Analytical Biochemistry, 397(2), 181-185.
  8. Ariffin, H., Garcia, J. C., Daud, S. S., Ibrahim, K., Aizah, N., Ong, G. B., ... & Mohamad, Z. (2009). GATA1 mutations in patients with down syndrome and acute megakaryoblastic leukaemia do not always confer a good prognosis. Pediatric blood & cancer, 53(1), 108-111.
  9. Ariffin, H., Martel-Planche, G., Daud, S. S., Ibrahim, K., & Hainaut, P. (2008). Li Fraumeni syndrome in a Malaysian kindred. Cancer genetics and cytogenetics, 186(1), 49-53.
  10. Ibrahim, K., Daud, S. S., Seah, Y. L., Yeoh, A. E., Ariffin, H., & Malaysia-Singapore Leukemia Study Group. (2008). Rapid detection of prognostically important childhood acute lymphoblastic leukemia chimeric transcripts using multiplex SYBR green real-time reverse transcription PCR. Annals of Clinical & Laboratory Science, 38(4), 338-343.
  11. Ariffin, H., Daud, S. S., & Ibrahim, K. (2007). QUANTITATIVE EVALUATION OF CHIMERISM STATUS FOLLOWING HAEMATOPOEITIC STEM CELL TRANSPLANTATION USING A MICROCHIP ELECTROPHORESIS SYSTEM. JUMMEC: Journal of Health and Translational Medicine (Formerly known as Journal of the University of Malaya Medical Centre), 10(1), 11-16.
  12. Ariffin, H., Daud, S. S., Mohamed, Z., Ibrahim, K., Lee, T. F., & Chong, L. A. (2007). Evaluation of two short tandem repeat multiplex systems for post-haematopoietic stem cell transplantation chimerism analysis. Singapore Medical Journal, 48(4), 333.
Article in Proceeding
  1. Rizalhanafi, F. N., Ramli, N., Narayanan, V., Rashid, K., Singh, J. K., & Ibrahim, K. (2021). OTEH-5. Characterization of long-non coding RNA associated ceRNA network hub gene involved in glioblastoma multiforme lipid metabolism. Neuro-oncology Advances, 3(Suppl 2), ii11. https://doi.org/10.1093/noajnl/vdab070.044

RESEARCH PROJECT


National
  1. 2019 - 2023, Fundamental Research Grant Scheme (FRGS)
    Investigation On The Functional Role Of Growth Arrest Specific 5 (gas5) Long Non-coding Rna In Glioblastoma Cells ( Principal Investigator(PI))
  2. 2021 - 2022, RU Geran
    Metabolism Reprogramming And Novel Translational Application Of Drug-Resistant Pancreatic Cancer: Potential Therapeutic Targets And Preclinical Studies ( Principal Investigator(PI))
  3. 2018 - 2020, Bantuan Kecil Penyelidikan (BKP)
    Integrative lncRNA-miRNA-mRNA regulatory network analysis in human thymic epithelial tumors ( Principal Investigator(PI))
  4. 2019 - 2022, Fundamental Research Grant Scheme (FRGS)
    Elucidation of long non-coding RNA ZFAS1 roles in modulating PTEN mutant and PTEN wild type glioblastoma multiforme cancer cell death ( Consultant)

PAPER PRESENTED


CONFERENCE
  1. MRI lipid signatures and SREBPs gene expression profiling for characterization of glioma: A preliminary study, ESNR 2020 Annual Meeting, European Society for Neuroradioloy (International) (05 Oct 2020 - 09 Oct 2020)
INVITED SPEAKER
  1. Understanding the Cancer Lipidomics (Invited Speaker), UKM Medical Molecular Biology Institute Research Update Series, No. 28/2019, UKM Medical Molecular Biology Institute  (University) (22 Nov 2019 - 22 Nov 2019)
  2. I've got my degree, where is my next stop?, TCL Career Talk, Translational Core Laboratory, Faculty of Medicine, University of Malaya (University) (27 Apr 2018 - 27 Apr 2018)
EVENT ORGANISER
  1. Research Forum Bridging Translational Cancer Research , Bridging Translational Cancer Research Forum in conjunction with the World Cancer Day, UM Cancer Research Institute, Committee Member, (University) (University) (03 Mar 2020 - 03 Mar 2020)
ORAL PRESENTER
  1. Covid19 Pandemic: Lesson learned for undergraduate research trainings, Teaching with big data (Conference), American Society for Biochemistry and Molecular Biology (International) (21 Jun 2021 - 25 Jun 2021)
POSTER PRESENTER
  1. IDENTIFICATION OF NON-CODING RNA INVOLVED IN GLIOBLASTOMA TUMOUR IMMUNE ESCAPE MECHANISM, 30th Annual Scientific Meeting, Malaysia Society of Neurosciences 2022, Malaysian Society of Neurosciences  (National) (01 Oct 2022 - 03 Oct 2022)
  2. Investigating GTF21-Related Network And Pathways In Human Thymic Epithelial Tumors, Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB) Congress 2021, Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB), New Zealand and Australia & IUBMB (International) (22 Nov 2021 - 25 Nov 2021)
  3. Characterization of long-non coding RNA associated ceRNA network hub gene involved in glioblastoma multiforme lipid metabolism, Society for Neuro-Oncology s Basic and Translational Omics of Brain Tumors and Their Microenvironment Conference, Society for Neuro-Oncology (International) (15 Jul 2021 - 16 Jul 2021)
  4. Identification of the Competing Endogenous RNA (CERNA) Network in Human Thymic Epithelial Tumors, 1st Malaysian Association for Cancer Research (MACR) Scientific Conference , Malaysian Association for Cancer Research (National) (03 Dec 2019 - 04 Dec 2019)
PRESENTER
  1. Identification of the Key Long Non-coding RNA in Glioma Lipid Metabolism, Basic Neuroscience Council (BNC) Hi-5 Retreat 2020: V-Symposium, to be held from 1st to 4th Dec, 2020., Persatuan Neurosains Malaysia (National) (01 Dec 2020 - 04 Dec 2020)
  2. Tousled-like kinase 1 knockdowninhibits glioblastoma cells invasion and migration via integrin mediated cell adhesion pathway, Stem Cell and Cancer Symposium 218, Kuala Lumpur, Faculty of Medicine, UM (International) (17 Oct 2018 - 18 Oct 2018)

ACADEMIC/PROF. SERVICES


Evaluation
  1. (2023) Muhammad Alif Naim Bin Md Khir (S2178172/1) Calon Ijazah Doktor Falsafah, Institut Pengajian Termaju, UM, University, (Internal Examiner)
  2. (2023) Thanusha M Ganesan, Phd Candidature Defense, Jabatan Farmakologi, Fom, UM, University, (Internal Examiner)
  3. (2023) Evaluation of Mr Jaiyogesh Patel Phd Proposal Defense, Jabatan Pediatrik, UM, University, (Internal Examiner)
  4. (2021) Ahli Panel Penilai Bagi Kertas Cadangan Di Bawah Fundamental Research Grant Scheme (Frgs) 1/2021 Peringkat Fakulti Farmasi, Universiti Malaya, University, (Reviewer)
  5. (2020) Journal of Health and Translational Medicine, #191062, 2019 , (Reviewer)
  6. (2020) Modulating effects of IL-4, IL-10 and IL-13 on the course of malaria infection (2020) , (Reviewer)
  7. (2020) DysregulatedMicro RNA Expression in R-CHOP Resistance/Early Relapse of Diffuse LargeB-Cell Lymphoma (Ting Choo Yuen, MHA150041) , (External Examiner)
  8. (2020) "Computational Prediction of MiR130a Target Genes in Cancer" , (Reviewer)
  9. (2018) The role of miR-548m in epithelial-mesenchymal transition in breast cancer cell lines (Master student candidature defence) , (Internal Examiner)
  10. (2018) DNA Chimerism Monitoring using INDEL in Haematopoietic Stem Cell Transplantation (University of Malaya - University College of London) June-Sept 2018 , (Course)
  11. (2018) Reviewer for Master project proposal - Molecular characterisation of biofilm formation in clinical-related Methicillin- Resistant and Methicillin-Sensitive Staphylococcus aureus (Sherry Anak Usun Jones) , (Internal Examiner)
  12. (2018) Reviewer for Master project proposal - Effects of Quinazoline Derivatives on Non Small Lung Cancer Xenografted in Zebrafish Embryos (Rose Amalina Ruslan), (Internal Examiner)
  13. (2018) Reviewer for a manuscript in the Journal of Asia Pacific Journal of Molecular Biology and Biotechnology (APJMBB) , (Reviewer)
  14. (2018) Abstract reviewer for the category Cancer for the 9th Malaysian Symposium of Biomedical Science 2018 , (Scientific Committee)
  15. Malaysian Journal of Medicine & Health Sciences, 2019 , (Reviewer)
  16. Examiner Proposal Defense (Master), Chin Tong Foh, MGN15005, Jabatan Pediatrik, (Internal Examiner)
  17. Asia Pacific Journal of Molecular Biology and Biotechnology, 2020 , (Reviewer)
  18. The TNF- , IGF-1, IL-6, and IL-10 Levels in Patients with Asthmatic Bronchitis of Duhok Population in Iraq, JUMMEC,(2020) , (Editor)
  19. Tan Pak Kheong, Chemical modification of selected peptide drugs for enhanced therapy of type II diabetes mellitus (Phd Confirmation), (Internal Examiner)
  20. Understanding The Cancer Lipidomics, Nov 2019, (Invited Speaker)
  21. Thai Journal of Pharmaceutical Sciences, 2019 , (Reviewer)
  22. Immunotherapy for cancer prevention and treatment, Gan Chai Pei (Sept 2019), Phd Proposal Defense , (External Examiner)
Contribution to external organisation
  1. (2020) Research Forum Bridging Translational Cancer Research", UM Cancer Research Institute, Committee Member, (University), University
  2. (2020) Bridging Translational Cancer Research Forum in conjunction with the World Cancer Day, UM Cancer Research Institute
  3. (2020) Faculty of Medicine, Central Research Laboratories Restructuring Workshop Panel Member, Faculty of Medicine
  4. (2020) Lipidomic Study of Brain Cancer Cells: An In-vivo Study Towards Understanding the Underlying Lipogenesis and Lipid Metabolism Regulation Gliomas Growth, Glioma Research Group UM

SUPERVISION


Postgraduate Student
PhD/ Doctoral
  1. (2020) Investigating the Molecular Mechanisms of Growth Arrest 5 Long Non-Coding RNA in Human Glioblastoma Cells, Jesminder Kaur a/p Jaswant Singh
  2. (2020) Elucidation of Long Non-coding ZFAS1, Mechanism in Modulating Glioblastoma Multiforme cancer cells death, Muhammad Farid bin Dzulkifle
Master
  1. (2022) ELUCIDATION OF LONG NONCODING RNA, ZFAS1 ROLES IN MODULATING PTEN MUTANT AND PTEN WILD-TYPE GLIOBLASTOMA MULTIFORME (GBM) CANCER CELL DEATH, ENGKU MARYAM AFIFAH BINTI ENGKU OMAR AMIRUDDI (Universiti Teknologi Mara (Uitm))
  2. (2017) Synergistic Induction of Palmitic and Oleic Acids to Enhance M1 Macrophage Tumoricidal Activity against CT26 and 4T1 cells, Noorzaileen Eileena binti Zaidi (M0100103)
Under Graduate Students
  1. (2022) Identification of non-coding RNA involved in metabolic reprogramming of pancreatic cancer.
  2. (2021) In Vivo Validation of Key Genes Implicated In Rotenone Neurotoxicity Identified From Computational Analysis

TEACHING


Bachelor
  1. (2020) MIC2006 - Bio-Risk Management for Biomedical Science
  2. (2020) MIC3002 - Fundamental Haematology
  3. (2020) MIC3006 - Blood Transfusion Technology
  4. (2020) MIC3007 - Cancer Biology
  5. (2019) MIC2010 - Immunology for Biomedical Science
  6. (2019) MIC3006 - Blood Transfusion Technology
  7. (2019) MIC3007 - Cancer Biology
  8. (2018) MIC2010 - Immunology for Biomedical Science
  9. (2018) MIC3006 - Blood Transfusion Technology
  10. (2017) MIC2006 - Bio-Risk Management for Biomedical Science
  11. (2017) MIC3002 - Fundamental Haematology
  12. (2017) MIC3007 - Cancer Biology

SOCIAL RESPONSIBILITY ACTIVITIES


  • Malaysian Brain Bee Challenge 2019, (15 Jan 2020 - 18 Mar 2020)
  • Bridging Translational Cancer Research Forum in Conjunction With The World Cancer Day, (03 Jan 2020 - 03 Mar 2020)
  • Mpkk Kg Sg Mahang (Biro Pendidikan), Nilai, Negeri Sembilan, (01 Jan 2019 - 01 Jan 2020)
  • Judge for Young Investigator Award / Oral Presentation At The Asean Regional Conference On Systems Biology, 20-22 November 2017, (20 Nov 2017 - 22 Nov 2017)