Curriculum Vitae

DR. LOH JIAN SHENG

Pharmacy Lecturer
  • Department of Pharmaceutical Life Sciences
    Faculty of Pharmacy
  • jsloh

BIOGRAPHY

Dr. Loh Jian Sheng is a registered pharmacist and Pharmacy Lecturer in the Department of Pharmaceutical Life Sciences, Faculty of Pharmacy. He obtained his PhD in Pharmaceutical Sciences from Monash University Malaysia, where his doctoral research integrated systems biology-guided target discovery, in vitro validation of microglial autophagy and neuroinflammatory responses, and in vivo pharmacokinetic and brain distribution assessment of intranasally administered zerumbone-loaded PEGylated liposomes for nose-to-brain delivery. Building on this foundation, his current and emerging research applies systems biology and experimental validation to identify disease-relevant targets and mechanisms, with growing interest in gut-derived metabolites and cross-organ communication. His scholarly work includes 11 Web of Science-indexed publications, including four first-author papers, one of which was published in Signal Transduction and Targeted Therapy and was designated a Web of Science Hot Paper. He also serves as an ad hoc reviewer for international journals such as Journal of Advanced Research, Industrial Crops and Products, Scientific Reports, and Journal of Cellular Biochemistry. 

ACADEMIC QUALIFICATION

  • IJAZAH DOKTORET/IJAZAH DOKTOR FALSAFAH (PHARMACEUTICAL SCIENCES), (Science Pharmacy)
    Monash University, (malaysia Campus)

PUBLICATIONS

Article in Journal
  1. Al-Ani, S. A., Lee, Q. Y., Maheswaran, D., Sin, Y. M., Loh, J. S., Foo, J. B., Hamzah, S., Ng, J. F., Tan, L. K. S. (2025). Potential of exosomes as multifunctional nanocarriers for targeted drug delivery. Molecular Biotechnology, 67(9), 3391–3414.
  2. Loh, J. S., Low, C. Y., Low, W. P., Ng, Y. L., Mak, W. Q., Tan, L. K. S., Chan, H. H., Ong, Y. S., Cheah, S. K. A., Albert, E. L., How, C. W. (2025). Traversing the valley of death for nanotechnology-based natural products: Strategies and insights from pharmaceutical stakeholders. Drug Delivery and Translational Research, 15(11), 4126–4140.
  3. Ng, C. X., Lee, S. Y., Yap, X. Y., Wong, Y. H., Loh, J. S., Ang, K. P., Lee, W. H., Xu, W., Yong, P. V. C., & Lee, S. H. (2025). Epigenetic reprogramming as the nexus of cancer stemness and therapy resistance: Implications for biomarker discovery. Discover Oncology, 16, 2220.
  4. Loh, J.S., Mak, W.Q., Tan, L.K.S., Ng, C.X., Chan, H.H., Yeow, S.H., Foo, J.B., Ong, Y.S., How, C.W., Khaw, K.Y. (2024). Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases, Signal Transduction and Targeted Therapy. 9, 37.
  5. Loh, J. S., Abdul Rahim, N., Tor, Y. S., Foo, J. B. (2022). Simultaneous proteasome and autophagy inhibition synergistically enhances cytotoxicity of doxorubicin in breast cancer cells. Cell Biochemistry and Function, 40(4), 403–416.
  6. Loh, J. S., Tan, L. K. S., Lee, W. L., Ming, L. C., How, C. W., Foo, J. B., Kifli, N., Goh, B. H., Ong, Y. S. (2021). Do Lipid-based Nanoparticles Hold Promise for Advancing the Clinical Translation of Anticancer Alkaloids? Cancers, 13(21), 5346.

RESEARCH INTEREST

  • Systems Biology-Guided Target Discovery (Systems biology, Network pharmacology, Bioinformatics)
  • Microbiota-Gut-Brain Axis in Neurodegenerative Diseases (Gut-brain axis, Neurodegenerative diseases)
  • Gut-Derived Metabolites & Cross-Organ Communication (Metabolites, Interorgan communication)
  • Microglial Autophagy & Neuroinflammation (Microglia, Autophagy, Neuroinflammation)

RESEARCH PROJECT

Private
  1. 2024 - 2024, 2024 High Impact Research Support Fund (HIRSF)
    Integrating Network Pharmacology with Module Analysis to Investigate the Neuroprotective Mechanisms of Zerumbone in Neurodegenerative Diseases ( Co-Researcher)

ACADEMIC/ PROF. SERVICES

Evaluation
  1. (2026) Reviewer for Scientific Reports, International, (Reviewer)
  2. (2025) Reviewer for Journal of Advanced Research, International, (Reviewer)
  3. (2025) Reviewer for Industrial Crops and Products, International, (Reviewer)
  4. (2025) Reviewer for Industrial Crops and Products, International, (Reviewer)
  5. (2025) Reviewer for Industrial Crops and Products, International, (Reviewer)
  6. (2025) Reviewer for Journal of Advanced Research, International, (Reviewer)
  7. (2025) Reviewer for Scientific Reports, International, (Reviewer)
  8. (2024) Reviewer for Scientific Reports, International, (Reviewer)
  9. (2024) Reviewer for Scientific Reports, International, (Reviewer)
  10. (2024) Reviewer for Scientific Reports, International, (Reviewer)