PERSONAL DETAIL


DR. JOHARI BIN MOHD ALI

Department of Molecular Medicine
Faculty of Medicine
 
  79675741
  79674957
  johari@um.edu.my
 Department of Molecular Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, W.Persekutuan Kuala Lumpur, Malaysia
 
ResearcherID Link
  http://www.researcherid.com/rid/B-5259-2010

ACADEMIC QUALIFICATION
(Qualification), (Institution).



PROFESSIONAL
(Organisation), (Role), (Year), (Level).


  • Malaysian Endocrine and Metabolic Society, Member, 2011 to 2014, (National)

ADMINISTRATIVE DUTIES
(Role), (Level), (Start date),(End Date).


  • Academic Advisor Stage 1 UMMP (Session 2017/2018), Faculty, 07/09/2017 to 01/06/2018
  • Comittee Member For Team Based Learning (TBL), UMMP Stage 1, Session 2017-2018, Faculty, 18/05/2017 to 14/06/2017
  • AHLI JAWATANKUASA IJAZAH TINGGI JABATAN, Faculty, 13/02/2017 to 17/12/2018
  • Academic Advisor for Phase I MBBS Students Session 2010/11(Group 18), University Malaya, 01/07/2010 to 30/06/2011

AREAS OF EXPERTISE
(Area).


  • Natural Product Drug Discovery
  • Molecular Analysis of Endocrine Disorders


RECENT SELECTED PUBLICATIONS
(Publication).


Article in Academic Journals

2018
  • Mohammad Faujul Kabir, Johari Mohd Ali*, Onn Haji Hashim. Microarray gene expression profiling in colorectal (HCT116) and hepatocellular (HepG2) carcinoma cell lines treated with Melicope ptelefolia leaf extract reveals transcriptome profiles exhibiting anticancer activity. PeerJ. (Accepted 20.6.18) (ISI-Indexed)

2017
  • Mohamad Zakkirun Abdullah, Johari Mohd Ali*, Mitra Abolmaesoomi, Puteri Shafinaz Abdul-Rahman & Onn Haji Hashim. Anti-proliferative, in vitro antioxidant and cellular antioxidant activities of the leaf extracts from Polygonum minus Huds: effects of solvent polarity..International Journal of Food Properties, 20: 846-862, DOI: 10.1080/10942912.2017.1315591 (ISI-Indexed)
  • Mohammad Faujul Kabir, Johari Mohd Ali* et al. Melicope ptelefolia leaf extracts exhibit antioxidant activity and exert anti-proliferative effect with apoptosis induction on four different cancer cell lines. BMC Complementary Alternative Medicine (Tier-1; ISSN 1472-6882; Accepted 26 April 2017) (ISI-Indexed)

2016
  • Fazliny Abd Rahman, Johari Mohd Ali, Mariam Abdullah, Noor Hayaty Abu Kasim, Sabri Musa. Aspirin enhances osteogenic potential of periodontal ligament stem cells (PDLSCs) and modulates the expression profile of growth factor-associated genes in PDLSCs. Journal of Periodontology (ISSN:0022-3492, PubMed 26846966) (ISI-Indexed)

2014
  • Johari Mohd Ali, Muhammad Yazid Jalaluddin, Fatimah Harun. Late onset X-linked adrenal hypoplasia congenita with hypogonadotropic hypgonadism due to a novel 4-bp deletion in exon 2 of NR0B1. Journal of Pediatric Endocrinology and Metabolism (ISSN 0334-018X). 10.1515/jpem-2014-0161 (ISI-Indexed)

2013
  • Suhaimi Hussain, Johari Mohd Ali, Muhammad Yazid Jalaludin, Fatimah Harun. Permanent Neonatal Diabetes due to a Novel Insulin Signal Peptide Mutation. Pediatric Diabetes. DOI: 10.1111/pedi.12011 (ISI-Indexed)
  • Hussain, S., Ali, J. M., Jalaludin, M. Y., Harun, F. 2013. Permanent neonatal diabetes due to a novel insulin signal peptide mutation Pediatric Diabetes. (Tier 2, Impact Factor = 2.077) (ISI-Indexed)

2011
  • Elsa Haniffah Mejia Mohamed, Tan Kay Sin, Johari Mohd Ali, Zahurin Mohamed. 2011 . TT genotype of the methylenetetrahydrofolate reductase C677T polymorphism is an important determinant for homocysteine levels in multi ethnic Malaysian ischaemic stroke patients. Ann Acad Med Singapore. 2011 Apr; 40(4):186-191.(Tier 3; Impact Factor = 1.25) (ISI-Indexed)

2003
  • Coldren CD, Hashim P, Ali JM, Oh SK, Sinskey AJ and Rha C (2003) Gene expression changes in the human fibroblast induced by Centella asiatica triterpenoids. Planta Med. 69(8):725-32. (ISI-Indexed)

1998
  • Ali JB, Sepp T, Ward S, Green AJ and Yates JR. Mutations in the TSC1 gene account for a minority of patients with tuberous sclerosis (1998). J. Med. Genet. 35, 969-972. (ISI-Indexed)

1997
  • van Slegtenhorst M, de Hoogt R, Hermans C, Nellist M, Janssen B, Verhoef S, Lindhout D, van den Ouweland A, Halley D, Young J, Burley M, Jeremiah S, Woodward K, Nahmias J, Fox M, Ekong R, Osborne J, Wolfe J, Povey S, Snell RG, Cheadle JP, Jones AC, Tachataki M, Ravine D, Sampson JR, Reeve MP, Richardson P, Wilmer F, Munro C, Hawkins TL, Sepp T, Ali JB, Ward S, Green AJ, Yates JR, Kwiatkowska J, Henske EP, Short MP, Haines JH, Jozwiak S, Kwiatkowski DJ. Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34 (1997). Science 8;277(5327):805-8. (ISI-Indexed)
Proceeding

2016
  • Mohammad Faujul Kabir, Johari Mohd Ali, Mitra Abolmaesoomi, Onn Hashim. Evaluation of Antioxdant and Anti-proliferative activities of Clinacanthus nutans extracts. 41st ANNUAL CONFERENCE OF THE MALAYSIAN SOCIETY FOR BIOCHEMISTRY & MOLECULAR BIOLOGY. 17th - 18th August 2016, Pullman Hotel, Bangsar, Kuala Lumpur. 
  • Mitra Abolmaesoomi, Johari Mohd Ali, Onn Hashim. Antioxidant and anti-proliferative activities of the fractions of Citrus hystrix ethyl acetate extract. 41st ANNUAL CONFERENCE OF THE MALAYSIAN SOCIETY FOR BIOCHEMISTRY & MOLECULAR BIOLOGY. 17th - 18th August 2016, Pullman Hotel, Bangsar Kuala Lumpur. 
  • Noor Shafina Mohamad Nor, Johari Mohd Ali. A Malaysian family with an activating mutation (S505R) in the Thyroid-stimulating Hormone Receptor (TSHR). The 9th Biennial Scientific Meeting of the Asia Pacific Paediatric Endocrine Society (APPES). Tokyo International Forum, Tokyo, JAPAN. 17-20 November 2016. 

2015
  • Mitra Abolmaesoomi, Johari Mohd Ali. Antioxidant and anti-proliferative activities of the fractions of Piper betel ethyl acetate extract. International Conference on Antioxidants and Degenerative Diseases (ICADD2015). 3rd- 4th June 2015. Hotel Istana, Kuala Lumpur, Malaysia. (Non-ISI/Non-SCOPUS)
  • Johari Mohd Ali, Fatimah Harun, Long Kha Chin. 2015. Combined Pituitary Hormone Deficiency: Mutation analysis of PROP1 and POU1F1 in a cohort of Malaysian patients. Human Genome Meeting 2015, Kuala Lumpur Convention Center, Malaysia, pg.97-98. (Non-ISI/Non-SCOPUS)

2014
  • Permanent Neonatal Diabetes (PNDM) Due To Heterozygous INS mutation. Asia Pacific Paediatric Endocrine Society (APPES) & Australasian Paediatric Endocrine Group (APEG) Joint Meeting (2014). (SCOPUS-Indexed)
  • Antioxidant and anticancer activities of Pandanus amarylliofolius, Piper betel, Citrus hystrix and Ficus deltoidea. The 39th Conference of the Malaysian Society for Biochemistry and Molecular Biology (Non-ISI/Non-SCOPUS)

2013
  • Song Hai Lim, Johari Mohd Ali, Loo Ling Wu. Familial non-autoimmune hyperthyroidism:activating mutation of thyrotropin receptor gene discovered after three generations of a family. 9th Joint Meeting of Pediatric Endocrinology, Milan, Italy (2013). (ISI-Indexed)
  • Antioxidant and Anticancer Activities of Polygonum minus, Alpinia galanga and Etlingera elatior. INTERNATIONAL CONFERENCE OF NATURAL PRODUCTS 2013. DOI: 10.2174/2210289201304010202. (Non-ISI/Non-SCOPUS)

2012
  • Permanent Neonatal Diabetes due to a novel insulin signal peptide mutation. 51st Annual Meeting European Society of Pediatric Endocrinology 2012 (ESPE 2012). Hormone Research In Pediatrics. Vol. 78, Suppl. 1, 2012. (ISI-Indexed)

2011
  • ANTIOXIDANT AND ANTICANCER ACTIVITIES OF PITHECELLOBIUM JIRINGA. Maysam Hafezparast mavaddat, Johari bin Mohd Ali and Azlina Abdul Aziz. 36 Annual Conference of the Malaysian Society of Biochemistry & Molecular Biology. 27-28 July 2011. (Non-ISI/Non-SCOPUS)

2010
  • Hooi Leng Ooi, Loo Ling Wu, Johari Mohd Ali, Ali Saber Hossein Abadi. 2010. Report of a rare case of Vitamin D - Dependent Rickets Type II Asia Pacific Paediatric Endocrinology Society (APPES) 6th. Biennial Scientific Meeting. November 17-20, 2010, Xian, China. (Non-ISI/Non-SCOPUS)
  • Johari Mohd Ali, Zahidah Ismail, Fatimah Harun. A novel 13-bp deletion (p.Pro19fsX3) in exon 1 of CYP27B1 in a patient with Vitamin D Dependent Rickets Type 1 (VDDR1) (Abstract). ESPE2010, Prague, Czech Republic. Hormone Research (2010). (ISI-Indexed)

2009
  • Mohd Ali J, Chin LK, Harun F. Laron syndrome due to a novel missense mutation p.W68L in the growth hormone receptor (2009). ESPE2009, New York, USA. Horm Res 72 (S3):199 (ISI-Indexed)

2007
  • Johari Mohd Ali, Long Kha Chin, Fatimah Harun CYP27B1 gene mutations in two rickets patients with 1a- hydroxylase deficiency. ESPE 2007, Helsinki, Finland. Horm Res 2007; 68 (S1):71. (ISI-Indexed)

2006
  • Johari Bin Mohd Ali, Long Kha Chin, Fatimah Harun. A silent polymorphism GGC>GGT(GLY241) in the Growth Hormone Receptor is a putative splice donor site. ESPE 2006, Rotterdam, The Netherlands. Hormone Res 2006; 65 (S4):163 (ISI-Indexed)
  • Elsa Haniffah Mejia Mohammed, Tan KS, Mohammed Z, Johari Mohd Ali, Tan CT. Angiotensin Converting Enzyme Deletion (ACE D) polymorphism and Ischaemic Stroke in Multi-Ethnic Malaysian Population. 15th IUPHAR World Congress of Pharmacology, Beijing, China. Acta Pharmacologica Sinica 2006; 27(S1):232. (ISI-Indexed)

2005
  • Long Kha Chin, Johari Bin Mohd Ali, Fatimah Harun. Molecular Screening of Frequent CYP21 Mutations by Allele Specific PCR in Patients With Congenital Adrenal Hyperplasia (CAH). ESPE 2005, Lyon, France. Hormone Res 2005; 64(S1):330 (ISI-Indexed)

AREAS OF RESEARCH
(Project title), (Role), (From)-(Until), (Level), (Source).


  • Thyroid Disorders In Malaysia - A Nationwide Multicentre Study, Co-Investigator, 2014 - 2016, Malaysian Endocrine & Metabolic Society, (National)
  • Evaluation Of Antioxidant Property And Antiproliferative Activity Of Kantan (etlingera Elatior), Pokok Kesum (polygonum Minus) And Lengkuas (alpinia Galangal) Towards Breast And Colon Cancer Cell Lines, Principal Investigator(PI), 2012 - 2015, Geran Penyelidikan Universiti Malaya (UMRG) - HTM (Wellness), (University)
  • The effect of extracts from Pithecellobium Jiringa, Barringtonia Racemosa, Muraya Koenigi and Boraga Officinalis on the expression and proteomic profiles of normal and breast cancer cell lines, Principal Investigator(PI), 2010 - 2011, Geran Penyelidikan Universiti Malaya (UMRG), (National)
  • Mutation analysis of genes invovled in growth disorders, Principal Investigator(PI), 2008 - 2009, Short Term Research Fund (Vote F)(PJP), (National)

AWARDS AND RECOGNITIONS
(Name of Award), (Awarding Institution), (Year Awarded), (Level).


  • Khidmat Setia 20 Award, 2014
  • Certificate of Excellent Service, University Malaya, 2012, (University)

PRESENTATIONS
(Title), (Event), (Date Presented), (Organiser), (Level).


POSTER
  • A novel 13-bp deletion (p.Pro19fsX3) in exon 1 of CYP27B1 in a patient with Vitamin D Dependent Rickets Type 1 (VDDR1) , 49th Annual Meeting of the European Society of Pediatric Endocrinology (ESPE), 2010-09-22 to 2010-09-25, European Society for Pediatric Endocrinology, (International)

EVALUATION ACTIVITIES
(Description), (Evaluation Activity),(Year).


  • PhD Thesis Examiner - "Association of Genetic Polymorphisms of Dipeptidyl Peptidase-4 with Type 2 Diabetes Mellitus in Malaysian Subjects" by RADWAN HAMOUD ALI AHMED (MHA130027), Thesis ,  (2017 - 2017)

SUPERVISION


POST GRADUATE STUDENT
(Name of Degree), (Name of Candidates), (Title of Thesis), (Academic Session)

Completed
  • Doctoral Degree (phd), Fazliny Abd Rahman, EFFECT OF ASPIRIN ON OSTEOGENIC DIFFERENTIATION AND GENE EXPRESSION PROFILES IN PERIODONTAL LIGAMENT STEM CELLS, 2013/2014
  • Master Degree, Mohd Zakkirun Abdullah, ANTIOXIDANT AND ANTIPROLIFERATIVE ACTIVITIES OF POLYGONUM MINUS, ALPINA GALANGAL AND ETLINGERA ELATIOR, 2011/2012
  • Master Degree, Dr. Rashidah Yasin, The Prevalence of Maturity Onset Diabetes of the Young 3 (MODY3) Mutation in Patients with Early Oset Type 2 Diabetes Mellitus, 2009/2010
  • Master Degree, Dr Elsa Haniffah Mejia Mohamed, Methylenetetraydrofolate reductase (MTHFR) C677T polymorphism and fasting hyperhomocysteinaemia are risk factors for ischaemic stroke: a tri-ethnic case-control study in Malaysian patients, 2008/2009
  • Master Degree, Long Kha Chin, DNA Mutation Analysis of Endocrine Disorders: Congenital Adrenal Hyperplasia (CAH), Combined Pituitary Hormone Deficiency (CPHD) & Vitamin D-Dependent Rickets Type I (VDDR1), 2006/2007