Curriculum Vitae
AREAS OF EXPERTISE
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NATURAL PRODUCTS CHEMISTRYnatural products, indole alkaloids, molecular docking, enzyme kinetic
ACADEMIC QUALIFICATION
- PhD, (Natural Products Chemistry)Universiti Malaya (UM)
- BSc (Chem), (Sains Kimia)Universiti Malaysia Terengganu (UMT)
ADMINISTRATIVE DUTIES
- AHLI JAWATANKUASA UNIT PENYELIDIKAN PASUM27 Jul 2023 - 08 Jun 2025 (Faculty)
- Committee Members10 Jan 2024 - 18 Jan 2024 (Department)
- Committee Members10 Jan 2024 - 18 Jan 2024 (Department)
- Ahli Jawatankuasa Tadbir Urus Permohonan Geran Penyelidikan di Peringkat Universiti Malaya 202301 Jan 2023 - 31 Dec 2023 (University Malaya)
- Coordinator12 Jul 2022 - 31 Dec 2023 (Chemistry Division, Centre for Foundation Studies in Science)
- Task Force Member06 Oct 2022 - 31 Mar 2023 (Faculty)
- Committee Members24 Nov 2022 - 12 Jan 2023 (Department)
- Committee Members01 Jan 2022 - 31 Dec 2022 (University Malaya)
- Committee Members14 Jul 2022 - 14 Sep 2022 (International)
- Committee Members01 Jul 2022 - 10 Aug 2022 (Faculty)
- Committee Members16 May 2022 - 16 Jun 2022 (Faculty)
- Committee Members13 Jun 2022 - 16 Jun 2022 (Faculty)
- Committee Members15 Aug 2021 - 26 Mar 2022 (Faculty)
- Committee Members01 Aug 2021 - 23 Jan 2022 (Faculty)
- Committee Members22 Nov 2021 - 10 Jan 2022 (Faculty)
- AJK PENILAIAN DAN PEMANTAUAN KANTIN PASUM03 Jul 2019 - 30 Jun 2021 (Director Office, Centre for Foundation Studies in Science)
- AJK PERPUSTAKAAN PASUM03 Jul 2019 - 30 Jun 2021 (Director Office, Centre for Foundation Studies in Science)
- AJK PERSIDANGAN, PENYELIDIKAN DAN PENERBITAN PASUM03 Jul 2019 - 30 Jun 2021 (Director Office, Centre for Foundation Studies in Science)
- TREASURER - 3rd INTERNATIONAL STEM SEMINAR (ISS 2021)26 Feb 2021 - 25 May 2021 (International)
- TREASURER-WEBINAR STEM PASUM10 Sep 2020 - 18 Dec 2020 (National)
- AHLI BIRO SEKRETARIAT & PENDAFTARAN DALAM MINGGU SUAI KENAL PELAJAR PASUM SESI 2020/202117 Jun 2020 - 11 Aug 2020 (Director Office, Centre for Foundation Studies in Science)
- TREASURER- JOGATHON PASUM, SESSION 2019/202029 Oct 2019 - 22 Feb 2020 (Faculty)
- Ahli Jawatankuasa Unit Pengurusan Makmal Kimia Pusat Asasi Sains Universiti Malaya29 Jan 2019 - 31 Dec 2019 (Chemistry Division, Centre for Foundation Studies in Science)
- AHLI JAWATANKUASA SIMPOSIUM SAINS DAN MATEMATIK KEBANGSAAN 201911 Feb 2019 - 31 Dec 2019 (University Malaya)
- AHLI BIRO SEKRETARIAT & PENDAFTARAN DALAM MINGGU SUAI KENAL PELAJAR PASUM SESI 2019/202029 Jun 2019 - 02 Jul 2019 (Faculty)
- KETUA BIRO PENGURUSAN DAN PENDAFTARAN BAGI MAJLIS ANUGERAH EMAS PUSAT ASASI SAINS UNIVERSITI MALAYA12 Feb 2019 - 23 Mar 2019 (Chemistry Division, Centre for Foundation Studies in Science)
- AHLI JAWATANKUASA 1ST NATIONAL SCIENCE AND MATHEMATICS SYMPOSIUM 201801 Mar 2018 - 31 Dec 2018 (Faculty)
- PENGARAH KOLOKIUM PENYELIDIKAN PASUM 2018 (KPP 2018)27 Feb 2018 - 21 Sep 2018 (Faculty)
- TIMBALAN KETUA BIRO ATURCARA & PROTOKOL DALAM MINGGU SUAI KENAL PELAJAR PASUM SESI 2018/201910 Jan 2018 - 27 Jun 2018 (Chemistry Division, Centre for Foundation Studies in Science)
- INTERNAL AUDITOR PUSAT ASASI SAINS UNIVERSITI MALAYA14 May 2018 - 18 May 2018 (Chemistry Division, Centre for Foundation Studies in Science)
- AHLI JAWATANKUASA MAJLIS PENYAMPAIAN ANUGERAH PASUM SESI 2017/201819 Dec 2017 - 07 Apr 2018 (Faculty)
- PETUGAS PAMERAN SEMPENA KARNIVAL PENDIDIKAN TINGGI NEGARA (KPTN) DI SHAH ALAM01 Apr 2018 - 01 Apr 2018 (National)
- Chairman of Technical, Transportation, Hospitality dan Food for International Malaysian-French Scientific Conference 2017 (IMFSC 2017)30 Mar 2017 - 21 Dec 2017 (International)
- SECRETARY OF INTERNATIONAL MALAYSIAN-FRENCH SCIENTIFIC CONFERENCE 2017 (IMFSC 2017)30 Mar 2017 - 21 Dec 2017 (International)
- AJK PENILAIAN SPESIFIKASI & HARGA PEROLEHAN BEKALAN ATAU PERKHIDMATAN UNTUK PERSIDANGAN ANTARABANGSA "INTERNATIONAL MALAYSIAN-FRENCH SCIENTIFIC CONFERENCE 2017" (IMFSC 2017)13 Nov 2017 - 21 Dec 2017 (Department of Chemistry, Faculty of Science)
- Social Committee12 Aug 2015 - 12 Aug 2015 (University Malaya)
- Logistic director for 9th Mathematics and Physical Sciences Graduate Congress (9th MPSGC)25 Nov 2013 - 10 Jan 2014 (Department of Chemistry, Faculty of Science)
MEMBERSHIPS
- MEMBER OF CENTRE FOR NATURAL PRODUCTS RESEARCH AND DRUG DISCOVERY (CENAR) , MEMBERSince 2021 (University)
- BOARD MEMBER OF INTERNATIONAL FRENCH-MALAYSIAN NATURAL PRODUCTS LABORATORY (IFM NATPROLAB), MEMBERSince 2019 (International)
- GOLDEN KEY INTERNATIONAL HONOUR SOCIETY, MEMBERSince 2008 (International)
- MEMBER OF INSITITUT KIMIA MALAYSIA (IKM), MEMBER2020 to 2023 (National)
- MEMBER OF THE ROYAL SOCIETY OF CHEMISTRY, MEMBER2015 to 2023 (International)
- TREASURER OF MINGGU SUAI KENAL PELAJAR PASUM SESI 2022/2023, TREASURER2022 to 2022 (University)
- TREASURER OF PROGRAM "EDUCATIONAL RESEARCH: QUESTIONNAIRE DEVELOPMENT AND VALIDATION", TREASURER2022 to 2022 (University)
- AHLI JAWATANKUASA TADBIR URUS PERMOHONAN GERAN PENYELIDIKAN DI PERINGKAT UNIVERSITI, MEMBER2022 to 2022 (University)
- AUDITOR DALAMAN BAGI AUDIT KENDIRI PASUM (KETUA AUDITOR BAGI SKOP PENYELIDIKAN), COMMITTEE MEMBER2021 to 2022 (University)
- AHLI JAWATANKUASA PELAKSANA PASUM BUDDY GROUP, MEMBER2021 to 2022 (University)
- MEMBER OF INSITITUT KIMIA MALAYSIA (IKM) , MEMBER2020 to 2022 (National)
- MEMBER OF THE ROYAL SOCIETY OF CHEMISTRY , MEMBER2015 to 2022 (International)
- SECRETARY OF UM-WOW MINGGU SUAI KENAL PELAJAR PASUM 2021/2022, SECRETARY2021 to 2021 (University)
- TEASURER OF 3RD INTERNATIONAL STEM SEMINAR (ISS 2021), TREASURER2021 to 2021 (International)
- TREASURER OF MAJLIS ANUGERAH EMAS PASUM 2020/2021, TREASURER2021 to 2021 (University)
- VICE PRESIDENT OF INTERNAL RESEARCH WEBINAR 2021 (PASUM WEBCAST 2021), VICE PRESIDENT2021 to 2021 (University)
- AHLI JAWATANKUASA STEM PASUM 2021, COMMITTEE MEMBER2021 to 2021 (University)
- MEMBER OF INSITITUT KIMIA MALAYSIA (IKM), COMMITTEE MEMBER2020 to 2021 (National)
- ASSOCIATE MEMBER OF THE ROYAL SOCIETY OF CHEMISTRY, COMMITTEE MEMBER2015 to 2021 (International)
AWARD AND STEWARDSHIP
- Gold Medal KNOVASI 2023Universiti Kebangsaan Malaysia, 2023 (National)
- EXCELLENCE SERVICE AWARDUniversity of Malaya, 2023 (University)
- Bronze Medal-Teaching and Learning Poster Ideas (TALPI) 2021UiTM & Universitas Terbuka Indonesia, 2021 (International)
- Bronze Medal-KNOVASI 2021 (Interactive Mobile Virtual Reality Application For Chemistry Laboratory)Universiti Kebangsaan Malaysia, 2021 (National)
- Gold Medal - KNOVASI 2021 (Overcoming The Adversity: Science-Teacher-Student Partnership (STSP) For The Development Of Integrated STEM Instructional Practices)Universiti Kebangsaan Malaysia, 2021 (National)
- CERTIFICATE OF EXCELLENT SERVICEUniversity of Malaya, 2021 (University)
- BEST POSTER PRESENTER (FIRST PLACE) IN INTERNATIONAL CONFERENCE ON NATURAL SCIENCE AND HERITAGE FROM ISLAMIC PERSPECTIVE 2018 (INSPIRE 2018)USIM & UM, 2018 (International)
- Bronze Medal In Poster Exhibition (Research) In Conjunction With Minggu Terbuka Akademik APIUM (MiTA' 18)Academy of Islamic Studies, University of Malaya, 2018 (Ptj/ Faculty)
- Best Poster Award in 4th International Conference on Computation for Science and Technology (ICCST 2016)Universiti Sains Malaysia, 2016 (International)
- UM EXCELLENCE AWARDNAIB CANSELOR, 2015 (University)
- University Malaya Excellence Award 2015 (PhD Graduate 2014 - 4 years or less)University of Malaya, 2015 (University)
- Training scholarship from the French EmbassyFrench Embassy in Malaysia, 2013 (International)
- Unique Team Presentation Award (The Fourth HOPE Meeting)Japan Society for the Promotion of Science, 2012 (International)
- Best Academic Award for the Faculty Science and Technology (UMT)Universiti Malaysia Terengganu, 2010 (University)
- Best Academic Award (UMT) in hostelUniversiti Malaysia Terengganu, 2010 (University)
- Dean?s List AwardUniversiti Malaysia Terengganu, 2010 (University)
- Dean?s List AwardUniversiti Malaysia Terengganu, 2009 (University)
- Dean?s List AwardUniversiti Malaysia Terengganu, 2008 (University)
- Dean?s List AwardUniversiti Malaysia Terengganu, 2007 (University)
PUBLICATIONS
Article in Journal
WoS
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Abd Rahman, Siti Nor Aisyah; Derbre, Severine; Rahman, Syarifah Nur Syed Abdul; Yap, Lee Fah; Lim, Chi-Wah Bryan; Tan, Siow-Ping; Awang, Khalijah; Zahari, Azeana; Liew, Sook Yee; Othman, Muhamad Aqmal (2024). 13C NMR-based dereplication analysis of cytotoxic styryl lactones from Goniothalamus giganteus against OSCC, JOURNAL OF MOLECULAR STRUCTURE. 1308. doi:10.1016/j.molstruc.2024.138245
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Chin, Ee-Zhen; Chang, Wei-Jin; Tan, Hui-Yin; Liew, Sook Yee; Lau, Yee-Ling; Ng, Yee-Ling; Nafiah, Mohd Azlan; Kurz, Thomas; Tan, Siow-Ping (2024). Synthesis and biological evaluation of hydantoin derivatives as potent antiplasmodial agents, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 103. doi:10.1016/j.bmcl.2024.129701
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Leong, Sow Tein; Liew, Sook Yee; Tiamas, Shelly Gapil; Hazni, Hazrina; Awang, Khalijah (2024). Chemical constituents from Mesua lepidota T. Anderson and their chemotaxonomic significance, BIOCHEMICAL SYSTEMATICS AND ECOLOGY. 114. doi:10.1016/j.bse.2024.104818
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Lim, Bryan Chi Wah; Tan, Siow-Ping; Keng, Xin-Yi; Ng, Win-Nie; Loh, Khye Er; Nafiah, Mohd Azlan; Liew, Sook Yee (2024). A New Compound from Tradescantia spathacea Leaves, CHEMISTRY OF NATURAL COMPOUNDS. . doi:10.1007/s10600-024-04393-5
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Osman, Norfaizah; Awang, Khalijah; Khaw, Kooi Yeong; Mak, Wen Qi; Tiamas, Shelly Gapil; Maulana, Saipul; Zubair, Muhammad Sulaiman; Pudjiastuti, Pratiwi; Hazni, Hazrina; Liew, Sook Yee; Zahari, Azeana (2024). Indole alkaloids from Ochreinauclea maingayi (Rubiaceae) as butyrylcholinesterase inhibitors and their paralysis effect in transgenic Caenorhabditis elegans, NATURAL PRODUCT RESEARCH. . doi:10.1080/14786419.2024.2394096
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Othman, Noor Aimi; Liew, Sook Yee; Khaw, Kooi Yeong; Ablat, Abdulwali; Karsani, Saiful Anuar; Leong, Kok Hoong; Blanchard, Patricia; Derbre, Severine; Awang, Khalijah (2024). Secondary metabolites from the barks of Garcinia griffithii T. Anderson (Clusiaceae) and their chemophenetic significance, BIOCHEMICAL SYSTEMATICS AND ECOLOGY. 116. doi:10.1016/j.bse.2024.104869
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Salleh, Haslinda Mohd; Ablat, Abdulwali; Chong, Soon-Lim; Hazni, Hazrina; Tohar, Norsita; Fauzi, Nurulwahidah; Wahab, Habibah A.; Othman, Muhamad Aqmal; Liew, Sook Yee; Awang, Khalijah (2024). The protective effects of Zingiber zerumbet rhizome against fevers in rats, SCIENCE OF NATURE. 111(2). doi:10.1007/s00114-024-01907-7
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Sukumaran, S. Yaallini; Herrscher, Charline; Rasol, Nurulfazlina Edayah; Othman, Muhamad Aqmal; Liew, Sook Yee; Ismail, Nor Hadiani; Seron, Karin; Litaudon, Marc; Awang, Khalijah; El Kalamouni, Chaker; Apel, Cecile; Zahari, Azeana (2024). Targeted Isolation of Antiviral Labdane Diterpenes from the Bark of Neo-uvaria foetida (Annonaceae) using LC-MS/MS-Based Molecular Networking, JOURNAL OF NATURAL PRODUCTS. . doi:10.1021/acs.jnatprod.4c00342
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Chang, Wei-Jin; Liew, Sook Yee; Tan, Siow-Ping (2023). Synthesis of N,N-diethylaminopropylurea and Monosubstituted Urea Derivatives from Primary Amines and Potassium Cyanate, LETTERS IN ORGANIC CHEMISTRY. 20(9), 877-882. doi:10.2174/1570178620666230330083659
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Cho, Kin-Hau; Tan, Siow-Ping; Tan, Hui-Yin; Liew, Sook Yee; Nafiah, Mohd Azlan (2023). Morphinan Alkaloids from the Leaves of Alphonsea cylindrica and Their Antibacterial Properties, PLANTA MEDICA. 89(01), 79-85. doi:10.1055/a-1797-0548
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Hasnan, Muhammad Hafiz Husna; Sivasothy, Yasodha; Khaw, Kooi Yeong; Nafiah, Mohd Azlan; Hazni, Hazrina; Litaudon, Marc; Ruzali, Wan Adriyani Wan; Liew, Sook Yee; Awang, Khalijah (2023). N-Methyl Costaricine and Costaricine, Two Potent Butyrylcholinesterase Inhibitors from Alseodaphne pendulifolia Gamb., INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 24(13). doi:10.3390/ijms241310699
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Leong, Sow Tein; Liew, Sook Yee; Khaw, Kooi Yeong; Hassali, Hazlina Ahmad; Richomme, Pascal; Derbre, Severine; Lee, Vannajan Sanghiran; Yahya, Ruzanna; Awang, Khalijah (2023). 13C NMR-based dereplication using MixONat software to decipher potent anti-cholinesterase compounds in Mesua lepidota bark, BIOORGANIC CHEMISTRY. 141. doi:10.1016/j.bioorg.2023.106859
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Liew, S. Y.; Sivasothy, Y.; Shaikh, N. N.; Javaid, K.; Isa, D. M.; Lee, V. S.; Choudhary, M. I.; Awang, K. (2023). Natural -glucosidase inhibitors from selected medicinal plants in Malaysia, JOURNAL OF THE NATIONAL SCIENCE FOUNDATION OF SRI LANKA. 51(2), 299-309. doi:10.4038/jnsfsr.v51i2.11177
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Liew, Sook Yee; Mak, Wen Qi; Thew, Hin Yee; Khaw, Kooi Yeong; Hazni, Hazrina; Litaudon, Marc; Awang, Khalijah (2023). Neuroprotective Activities of New Monoterpenoid Indole Alkaloid from Nauclea officinalis, PROCESSES. 11(3). doi:10.3390/pr11030646
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Tan, Siow-Ping; Keng, Xin-Yi; Lim, Bryan Chi-Wah; Liew, Sook Yee; Nafiah, Mohd Azlan (2023). Isolation of Natural Steroids from Corn Silk Using Recycling Preparative HPLC: A Natural Products Discovery Assignment for the Undergraduate Chemistry Student, JOURNAL OF CHEMICAL EDUCATION. 100(10), 3825-3831. doi:10.1021/acs.jchemed.2c01187
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Min, Shereen Lai Shi; Liew, Sook Yee; Chear, Nelson Jeng Yeou; Goh, Bey Hing; Tan, Wen-Nee; Khaw, Kooi Yeong (2022). Plant Terpenoids as the Promising Source of Cholinesterase Inhibitors for Anti-AD Therapy, BIOLOGY-BASEL. 11(2). doi:10.3390/biology11020307
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Othman, Noor Aimi; Liew, Sook Yee; Blanchard, Patricia; Derbre, Severina; Chong, Soon-Lim; Ali, Abdul Manaf; Awang, Khalijah (2022). (+)-Neocadambine A and (-)-Nauclederine Isolated from the Bark of Neolamarckia cadamba (Rubiaceae) as Natural Advanced Glycation End Products (AGEs) Inhibitors, SAINS MALAYSIANA. 51(6), 1725-1732. doi:10.17576/jsm-2022-5106-10
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Qureshi, A. K., Liew, S. Y., Othman, N. A., & Awang, K. (2021). Phytochemical constituents from Neolamarckia cadamba (Roxb.) Bosser. Biochemical Systematics and Ecology, 96, 5. doi: 10.1016/j.bse.2021.104257
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Sivasothy, Y., Liew, S. Y., Othman, M. A., Wahab, S. M. A., Hariono, M., Nawi, M. S. M., . . . Awang, K. (2021). Natural DENV-2 NS2B/NS3 protease inhibitors from Myristica cinnamomea King. Tropical Biomedicine, 38(2), 79-84. doi: 10.47665/tb.38.2.044
Scopus
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Hematpoor A., Liew S.Y., Omar H., Shilpi J.A., Zahari A., Syamsir D.R., Salleh H.M., Tohar N., Kim R.P.T., Qureshi A.K., Nasrullah A.A., Chan G., Tiong S.H., Hamdi O.A.A., Othman M.R., Leong S.T., Awang K., Mawi M., Asib N. (2022). Toxicity of Malaysian Medicinal Plant Extracts against Sitophilus oryzae and Rhyzopertha dominica, Pertanika Journal of Tropical Agricultural Science. 45(4), 1137-1160. doi:10.47836/pjtas.45.4.17
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Chin, E. Z., Tan, S. P., Liew, S. Y., & Kurz, T. (2021). Synthesis and characterization of amino acid-derived hydantoins. Malaysian Journal of Chemistry, 23(2), 19-25.
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Kim, R. P. T., Khan, M. N., Liew, S. Y., & Awang, K. (2021). Kinetic and mechanistic studies of acidic hydrolysis of goniothalamin. Asian Journal of Chemistry, 33(5), 1176-1182. doi: 10.14233/ajchem.2021.23158
Others
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Kim, R.P.T., Liew, S.Y., Awang, K. (2020). Phytochemical constituents from the stem barks of Goniothalamus tapis Miq. Biochemical Systematics and Ecology, 93, 104185.
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Lam, M.C., Tee, H.K., Muhammad Nizam, S.S., Che Hashim, N., Suwadi, N.A., Tan, S.Y., Abd Majid, N.A., Arshad, H., Liew, S.Y. (2020). Interactive Augmented Reality with Natural Action for Chemistry Experiment Learning. TEM Journal, 9(1), 351-360.
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Liew, S.Y., Sivasothy, Y., Shaikh, N.N., Mohd Isa, D., Lee, V.S., Choudhary, M.I., Awang, K. (2020). -Glucuronidase inhibitors from Malaysian plants. Journal of Molecular Structure, 128743.
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Nur Affira Mohd Noor, Mohd Azlan Nafiah, Syed Ahmad Tajudin Tuan Johari, Muhammad Hafiz Husna Hasnan, Siow-Ping Tan, Sook Yee Liew, Unang Supratman. (2019). Anticancer Effect of Hypophyllanthin, Niranthin and Lintetralin From Phyllanthus amarus on HeLa Cells And NIH/3T3 Cells. International Journal of Recent Technology and Engineering (IJRTE), 8(2S7), 106-110.
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Salleh, H.M, Chong, S.-L., Othman, R., Hazni, H., Ahmad, K., Mohd Yusof, M.Y.Z., Wahab, H.A., Liew, S.Y. and Awang, K. (2019). Dengue protease inhibition activity of selected Malaysian medicinal herbs. Tropical Biomedicine, 36(2), 357-366.
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Syazreen N. Sulaiman, Maywan Hariono, Haslinda Mohd Salleh, Soon-Lim Chong, Sook Yee Liew, Azeana Zahari, Habibah A. Wahab, Severine Derbr , and Khalijah Awang. (2019). Chemical Constituents From Endiandra kingiana (Lauraceae) as Potential Inhibitors for Dengue Type 2 NS2B/NS3 Serine Protease and its Molecular Docking. Natural Product Communications, 14(9),1934578X19861014.
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Hematpoor A, Paydar M, Liew SY, Sivasothy Y, Mohebali N, Looi CY, Wong WF, Azirun MS, Awang K. (2018). Phenylpropanoids isolated from Piper sarmentosum Roxb. induce apoptosis in breast cancer cells through reactive oxygen species and mitochondrial-dependent pathways. Chemico-Biological Interactions, 279, 210-218.
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Sulaiman, S.N., Zahari, A., Liew, S.Y., Litaudon, M., Issam, A.M., Wahab, H.A., Awang, K. (2018). Pahangine A and B, two new oxetane containing neolignans from the barks of Beilschmiedia glabra Kosterm (Lauraceae). Phytochemistry Letters, 25, 22-26.
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Hematpoor, A., Liew, S.Y., Azirun, M.S., Awang, K. (2017). Insecticidal activity and the mechanism of action of three phenylpropanoids isolated from the roots of Piper sarmentosum Roxb. Scientific Reports, 7, 12576.
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Wan Othman, W. N. N.,Sivasothy, Y., Liew, S. Y., Mohamad, J., Nafiah, M. A., Ahmad, K., Litaudon, M., Awang, K. 2017. Alkaloids from Cryptocarya densiflora Blume (Lauraceae) and their cholinesterase inhibitory activity. Phytochemistry Letters 21(2017):230-236.
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Hematpoor,A., Liew,S.Y., Chong,W.L., Sofian Azirun,M., Lee,V.S., Awang,K. 2016. Inhibition and larvicidal activity of phenylpropanoids from Piper sarmentosum on acetylcholinesterase against mosquito vectors and their binding mode of interaction. Plos One. 11(5): e0155265.
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Nor Hayati Abdullah, Noel F. Thomas, Yasodha Sivasothy, Vannajan Sanghiran Lee, Sook Yee Liew, Ibrahim Ali Noorbatcha, Khalijah Awang. Hyaluronidase inhibitory activity of pentacylic triterpenoids from Prismatomeris tetrandra (Roxb.) K. Schum: Isolation, synthesis and QSAR study. International Journal of Molecular Sciences. 2016, 17 (2), 143.
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Siti Mariam Abdul Wahab, Yasodha Sivasothy, Liew Sook Yee, Marc Litaudon, Jamaludin bin Mohamad, Khalijah Awang. 2016. Natural Cholinesterase Inhibitors from Myristica cinnamomea King. Bioorganic & Medicinal Chemistry Letters 26(15):3785-3792.
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Wan Nurul Nazneem Wan Othman, Sook Yee Liew, Kooi Yeong Khaw, Vikneswaran Murugaiyah, Marc Litaudon, Khalijah Awang. 2016. Cholinesterase inhibitory activity of isoquinoline alkaloids from three Cryptocarya species (Lauraceae). Bioorganic & Medicinal Chemistry. 24(18):4464-4469
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Liew, S.Y., Khaw, K.Y., Murugaiyah, V., Looi,C.Y., Wong,Y.L., Mustafa, M.R., Litaudon, M. & Awang, K. 2015. Natural indole butyrylcholinesterase inhibitors from Nauclea officinalis. Phytomedicine 22(1): 45-48.
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Liew, S.Y., Looi,C.Y., Paydar, M., Cheah, F.K., Leong, K.H., Wong,Y.L., Mustafa, M.R., Litaudon, M. & Awang, K. 2014. Subditine, a New Monoterpenoid Indole Alkaloid from Bark of Nauclea subdita (Korth.) Steud. Induces Apoptosis in Human Prostate Cancer Cells. PLoS ONE 9(2): e87286.
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Sook Yee Liew, Mat Ropi Mukhtar, A. Hamid A. Hadi, Khalijah Awang, Mohd Rais Mustafa, Kazumasa Zaima, Hiroshi Morita and Marc Litaudon, Naucline, a New Indole Alkaloid from the Bark of Nauclea officinalis, Molecules 2012, 17, 4028-4036
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Liew, S. Y., Mukhtar, M. R., Awang, K., Mustafa, M. R. & Ng, S.W. 2011. 1-(1-Hydroxyethyl)-7,8-dihydroindolo[2,3-a]pyridine[3,4-g]quinolizin-5(13H)one(angustoline) monohydrate from Nauclea subdita (Rubiaceae). Acta Crystallographica Section E: Structure Reports Online 67(7):o1727-o1728
Books
- Sonsudin, F., Sulaiman, M., Jaafar, M.H., Salleh, F.M., Omar, H., Shahabudin, N., Liew, S.Y., Mohd Rodzi, N., Azzahari, A.D., et al. (2020). Chemistry Course Laboratory Manual Semester 2, 2020/2021
- Saat, R.M., & Fadzil, H. M. (Eds.). (2019). Detection of alkaloid compounds in plant: Student s module. Kuala Lumpur, Malaysia: Faculty of Education, University of Malaya.
- Saat, R.M., & Fadzil, H. M. (Eds.). (2019). Detection of alkaloid compounds in plant: Teacher s module. Kuala Lumpur, Malaysia: Faculty of Education, University of Malaya.
- Jaafar, M.H., Ithnin, R., Sonsudin, F., Sulaiman, M., Omar, H., Salleh, F.M., Shahabudin, N., Liew, S.Y., Rahman, A.A., et. al. Chemistry Course Laboratory Manual Semester 2 Session 2017/2018
Article in Proceeding
- Tan, S.Y., Leow, C.F., Lam, M.C., Liew, S.Y., Koh, A.J.H. (2021). Interactive Mobile Virtual Reality Application for Chemistry Laboratory, Conference Proceeding: ASNet Virtual Conference on Education, Social Sciences and Technology 2021 (AVEST2021) (pp.47-59). Asian Scholars Network.
RESEARCH PROJECT
National
- 2024 - 2027, UNIVERSITI MALAYA RESEARCH EXCELLENCE GRANT (UMREG)Curcuminoids from Curcuma Zedoaria Roscoe and Curcuma Xanthorrhiza Roxb., and Their Anti-pigmentation Nanoemulsion Formulation ( Co-Researcher)
- 2024 - 2026, UM International Collaboration GrantChemical Profiling And Identification Of Cytotoxic Compounds From Goniothalamus Tapis With The Aid Of Lcms/ms Based Molecular Networking ( Principal Investigator(PI))
- 2021 - 2025, Fundamental Research Grant Scheme (FRGS)Isolation Of Covid-19 Antiviral Agents From Neo-uvaria Foetida And Miliusa Longipes Using Fast Lcms/ms Based Molecular Networking ( Co-Researcher)
- 2024 - 2024, Partnership Grant13C NMR-based Dereplication Analysis of Natural Compounds from Malaysian Plants ( Principal Investigator(PI))
- 2020 - 2023, RU Geran - Fakulti ProgramPhytochemical Studies Of Alseodaphne Pendulifolia And Alseodaphne Peduncularis ( Principal Investigator(PI))
- 2020 - 2023, Partnership GrantEnhancing the Value of Malaysian Plant Biodiversity ( Co-Researcher)
- 2021 - 2023, RU GeranInterdisciplinary And Target-based Development Of Nutraceuticals And Drugs For Prevention And Treatments Of Diseases ( Co-Researcher)
- 2021 - 2023, RU GeranNatural Hiv And Hepatitis C Inhibitors From Malaysian Flora ( Co-Researcher)
- 2023 - 2023, Partnership GrantPreserving Malaysian Annonaceae: A Search for SARS-CoV-2 and Dengue Antiviral Solutions ( Co-Researcher)
- 2019 - 2022, Others MOHE - Top 100 (IIRG)-FNWChemical Profiling Of Brucea Javanica `green? Formulation ( Co-Researcher)
- 2020 - 2022, International FundingMypair Hibiscus : Fast Dereplication Of Malaysian Herbal Extracts Using 13c Nmr (projet Demain) ( Co-Researcher)
- 2019 - 2021, Fundamental Research Grant Scheme (FRGS)Potential Natural Advanced Glycation End Products (ages) Inhibitors From The Bark Of Garcinia Griffithii And Neolamarckia Cadamba ( Principal Investigator(PI))
- 2018 - 2020, Bantuan Kecil Penyelidikan (BKP)Phytochemical and antidiabetic studies of Neolamarckia cadamba and Nauclea subdita ( Principal Investigator(PI))
- 2023 - 2025, Fundamental Research Grant Scheme (FRGS)Bioactivity-based Molecular Networking-guided identification of pancreatic lipase inhibitors from Tradescantia spathacea as anti-obesity candidates, Tunku Abdul Rahman University of Management and Technology (TAR UMT) ( Co-Researcher)
- 2022 - 2024, GERAN PEMBUDAYAAN PENYELIDIKAN UiTM CAWANGAN SELANGOR (DUCS-P) 2022Synthesis Of Macarubiginosin C And Its Derivatives As Potential Anti-alzheimer Agent, Universiti Teknologi Mara (UITM) ( Co-Researcher)
- 2019 - 2021, Fundamental Research Grant Scheme (FRGS)Potential Natural Advanced Glycation End Products (ages) Inhibitors From The Bark Of Garcinia Griffithii And Neolamarckia Cadamba ( Principal Investigator(PI))
- 2016 - 2020, GERAN PENYELIDIKAN KOMPETITIF (USIM-C)In-Depth Analysis Studies Of Zingiber Zerumbet According To Al-Quran, Ahadith And Old Malay Manuscript Into Scientific Research Towards Dengue Protease ( Consultant)
- 2018 - 2020, Bantuan Kecil Penyelidikan (BKP)Phytochemical And Antidiabetic Studies Of Neolamarckia Cadamba And Nauclea Subdita ( Principal Investigator(PI))
- 2012 - 2014, Postgraduate Research Grant(PPP)Chemical Constituents Of Two Species Of Rubiaceae (nauclea Officinalis And Nauclea Subdita) And Their Biological Activity (antiplasmodial,antioxidant And Neuroproctive) ( Consultant)
Private
- 2022 - 2023, EARLY CAREER RESEARCHER (ECR) GRANT SCHEME 2022Unravelling the potential of Murraya koneigii phytochemicals for the management of Alzheimer s disease, Monash University Malaysia campus ( Co-Researcher)
International
- 2024 - 2025, International FundingRapid Identification Of Natural Compounds From Malaysian Plants Using 13c Nmr-based Dereplication Technique With Mixonat Software ( Principal Investigator(PI))
- 2023 - 2024, International FundingAnti Neuroinflammatory Potential Of Alseodaphne Pendulifolia ( Principal Investigator(PI))
- 2022 - 2023, International FundingA Conservation Effort On Malaysian Annonaceae Plants And Its Identification On Novel Sarscov-2 And Dengue Antiviral Agents ( Co-Researcher)
- 2022 - 2023, International FundingThe Development Of A New Plant Sample Repository At Universiti Malaya ( Co-Researcher)
- 2020 - 2022, International FundingPotentials Of Drug And Phytopharmaceutical Candidates Of Malaysian Plant As A Cure And Health Supplements For The Treatment Of Covid-19 Infections ( Co-Researcher)
- 2020 - 2022, International FundingMyPAIR PHC-Hibiscus : Fast Dereplication Of Malaysian Herbal Extracts Using 13C NMR ( Consultant)
CONSULTANCY PROJECT
- Isolation and Characterization of 50-70 Natural Compounds from Malaysian Plants, National Institutes of Biotechnology, Institut Farmaseutikal dan Nutraseutikal Malaysia (IPharm)01 Dec 2017 - 01 Dec 2018 (National)
- Antioxidant Test: Dpph, Evaluation of Activity On 5-6 Different Concentrations in Triplicates, Determination of Ic50 and Final Report On 20 Food Samples, Sime Darby Technology Centre Sdn. Bhd.01 Dec 2017 - 01 Dec 2017 (National)
PAPER PRESENTED
INVITED SPEAKER
- A Success Story: The International French Malaysian Natural Products Laboratory (IFM NATPRDOLAB), Malaysia-France Convention on Higher Education, Research and Innovation 2023, Embassy of France in Kuala Lumpur (International) (18 Oct 2023 - 20 Oct 2023)
ORAL PRESENTER
- Studies On Chemical Constituents and Biological Activities of Rubiaceae Plants, Kolokium Penyelidikan Pusat Asasi Sains Universiti Malaya (PASUM) 2018 (KPP 2018), Jawatankuasa Penyelidikan PASUM dan Pusat Asasi Sains Universiti Malaya (PASUM) (University) (27 Feb 2018 - 27 Feb 2018)
- Chemical Constituents from Nauclea officinalis (Rubiaceae), 7th Mathematics and Physical Sciences Graduate Congress (7th MPSGC), National University of Singapore (International) (12 Dec 2011 - 14 Dec 2011)
POSTER PRESENTER
- INDOLE ALKALOIDS FROM NAUCLEA SPECIES , International Conference On Natural Science and Heritage from Islamic Perspective 2018 (INSPIRE 2018), USIM & UM (International) (06 Aug 2018 - 08 Aug 2018)
- CHOLINESTERASE INHIBITORY ACTIVITY OF ISOQUINOLINE ALKALOIDS FROM CRYPTOCARYA SPECIES (LAURACEAE), INTERNATIONAL MALAYSIAN-FRENCH SCIENTIFIC CONFERENCE 2017, IFM-NATPROLAB (PHYTOLAB), DEPARTMENT OF CHEMISTRY, FACULTY OF SCIENCE, UNIVERSITY OF MALAYA (International) (18 Dec 2017 - 19 Dec 2017)
- Enzyme Kinetic and Molecular Docking Studies of Natural Cholinesterase Inhibitors from Nauclea officinalis, 4th International Conference on Computation for Science and Technology (ICCST-2016), Universiti Sains Malaysia (International) (03 Nov 2016 - 04 Nov 2016)
- Natural Indole Cholinesterase Inhibitors from Nauclea officinalis, Annual Colloquium on Drug Development from Natural Products, Centre of Natural Products and Drug Discovery (CENAR) (National) (12 Aug 2015 - 12 Aug 2015)
- Cytotoxic Indole Alkaloids from Nauclea subdita (Rubiaceae), 9th Mathematics and Physical Sciences Graduate Congress (9th MPSGC) (International) (08 Jan 2014 - 10 Jan 2014)
- Alkaloids from The Bark and Leaves of Nauclea officinalis (Rubiaceae), 8th Mathematics and Physical Sciences Graduate Congress (8th MPSGC), Chulalongkorn University (International) (08 Dec 2012 - 10 Dec 2012)
- Alkaloids from The Bark and Leaves of Nauclea Officinalis (Rubiaceae), 4th HOPE Meetings (International) (07 Mar 2012 - 11 Mar 2012)
ACADEMIC/PROF. SERVICES
Evaluation
- (2024) The France-Malaysia Collaboration Programme for Joint Research 2024 (Mytiger 2024) Grant Application, International, (Reviewer)
- (2023) Penilai Dalaman Frgs 2024, University, (Reviewer)
- (2023) Geran Penyelidikan Negeri Selangor (Gpns) 2023 Application, National, (Reviewer)
- (2023) Examiner for Candidature Defence of Master Degree (Syaallini Sukumaran), University, (Internal Examiner)
- (2022) Reviewing Journal Article (Life-Mdpi), International, (Reviewer)
- (2022) Internal Panel/Reviewer of Frgs Grant 2022, University, (Reviewer)
- (2022) Auditor Dalaman Bagi Audit Kendiri Pasum (Ketua Auditor Bagi Skop Penyelidikan), University, (Internal Evaluator)
- (2021) Examiner for Proposal Defense of Doctor of Philosophy (Institut Pengajian Termaju), University, (External Examiner)
- (2021) Internal Evaluator for Frgs Proposal, University, (Internal Evaluator)
- (2020) Semakan soalan kaji selidik (Tajuk kajian: 'Green Practices and Corporate Sustainability Performance in Malaysia Chemical Manufacturing Organizations: The Moderating Role of Islamic Work Ethics, Organization Size and Organization Age'.), (Reviewer)
- (2020) Reviewer for manuscript: Pertanika Journal of Science and Technology (Special Issue_ Symposium of Applied Engineering and Sciences 2019) , (Reviewer)
- (2019) Examiner for PhD Candidature Defence (Phytochemical Studies and evaluation of their electrochemical and biological activities on Alseodaphne pendulifolia and Alseodaphne peduncularis (Lauraceae)) , (Internal Examiner)
- (2019) Examiner for PhD Candidature Defence (Phytochemical Studies Of Mesua Lepidota And Garcinia griffithii ) , (Internal Examiner)
- (2019) Examination for dissertation - MASTER OF MEDICAL SCIENCE (RESEARCH MODE) -Screening and Investigation of Apoptosis of Substituents Bearing A (3,4,5-Trimethoxybenzyloxy) Phenyl Moiety on Selected Colorectal Cancer Cell Lines , (Internal Examiner)
- (2019) Reviewer for Journal - BMC Complementary and Alternative Medicine: "Superoxide-producing lipoprotein fraction from Stevia leaves: definition of specific activity" , (Reviewer)
- (2019) INTERNAL PANEL FOR FRGS GRANT APPLICATION 2019 (PASUM) , (INTERNAL PANEL)
- (2018) Panel Semakan Dan Penilaian Dalam Bengkel Penyediaan Laporan Akhir TRGS , (Reviewer)
- (2017) PANEL SEMAKAN DAN PENILAIAN DALAM BENGKEL SEMAKAN BUKU "MAKANAN DAN MINUMAN DALAM PERSPEKTIF ILMU WAHYU DAN SAINS" , (Reviewer)
Contribution to external organisation
- (2024) Collaborative Research Agreement (Moa) With UiTM, National, (Resource Person)
- (2024) Collaborative Research Agreement (Moa) With Ird, International, (Resource Person)
- (2023) Ahli Panel Penilai Kertas Cadangan Mrun Research Officer Grant Scheme (Mrogs), National, (Resource Person)
- (2023) Research Agreement (Moa) With Icsn/Cnrs, International, (Resource Person)
- (2022) Collaborative Research Agreement (Moa) With Hokkaido University, International, (Resource Person)
Contribution to event
- (2021) Secretary of UM-Wow Minggu Suai Kenal Pelajar Pasum 2021/2022, University, (Event Coordinator)
- (2021) Teasurer of 3rd International Stem Seminar (Iss 2021), International, (Event Coordinator)
- (2021) Treasurer of Majlis Anugerah Emas Pasum 2020/2021, University, (Event Coordinator)
- (2021) Vice President of Internal Research Webinar 2021 (Pasum Webcast 2021), University, (Event Coordinator)
Mentoring
- (2022) Mentor of Pasum Students, University, (Mentor)
SUPERVISION
Postgraduate Student
PhD/ Doctoral
-
(2023) Secondary Metabolites of Neolamarckia cadamba and Garcinia griffithii with Their Advanced Glycation End Products and Alpha-Glucosidase Inhibitory Activities, NOOR AIMI BINTI OTHMAN @ GHAZALI
-
(2023) Bioassay-Guided Phytochemistry of Zingiber zerumbet (L.) Smith Rhizome Extract Against Dengue Virus Serotype-2 NS2B/NS3 Protease and its Anti-Pyretic Activities, HASLINDA BINTI MOHD SALLEH
-
(2022) Unravelling the potential of Murraya koneigii phytochemicals for the management of Alzheimer's disease, AI SZE WEE (Monash University Malaysia Campus)
-
(2015) PHYTOCHEMICAL STUDIES OF CURCUMA XANTHORRHIZA AND ZINGIBER ZERUMBET WITH THEIR BIOLOGICAL ACTIVITIES, HASLINDA BINTI MOHD SALLEH
-
(2014) CHEMICAL CONSTITUENT STUDIES OF NEOLAMARCKIA CADAMBA (ROXB) BOSSER AND THEIR BIOLOGICAL ACTIVITY, NOOR AIMI BINTI OTHMAN @ GHAZALI
Master
-
(2024) Phytochemical Study and Pancreatic Lipase Inhibitory Effects of Murraya Koenigii Roots by Molecular Networking Approach, CHONG WAI TING (Tunku Abdul Rahman University of Management and Technology (Tar UMT))
-
(2023) Bioactivity-Based Molecular Networking-guided Isolation and Identification of Pancreatic Lipase Inhibitors from Tradescantia spathacea, NG WIN NIE (Tunku Abdul Rahman University of Management and Technology (Tar UMT))
-
(2023) Secondary Metabolites from the Bark of Goniothalamus Giganteus and their Cytotoxic Activities, SITI NOR AISYAH BINTI ABD RAHMAN
Under Graduate Students
- (2023) CHEMICAL CONSTITUENTS FROM MYRISTICA CINNAMOMEA
- (2023) Chemical Constituents from Goniothalamus tapis (Annonaceae)
TEACHING
Others
- (2023) FAD1016 - Basic Chemistry 1
- (2023) FAD1018 - Basic Chemistry 2
- (2023) FAD1007 - Chemistry 3
- (2023) FAD1017 - Practical Chemistry 1
- (2023) FAD1019 - Practical Chemistry 2
- (2022) FAD1016 - Basic Chemistry 1
- (2022) FAD1005 - Chemistry 1
- (2022) FAD1006 - Chemistry 2
- (2022) FAD1007 - Chemistry 3
- (2022) FAD1008 - Chemistry 4
- (2022) FAD1017 - Practical Chemistry 1
- (2021) FAD1005 - Chemistry 1
- (2021) FAD1006 - Chemistry 2
- (2021) FAD1007 - Chemistry 3
- (2021) FAD1008 - Chemistry 4
- (2020) FAD1007 - Chemistry 3
- (2020) FAD1008 - Chemistry 4
- (2020) FAE1007 - Chemistry 1
- (2019) FAD1005 - Chemistry 1
- (2018) FAD1006 - Chemistry 2
- (2018) FAD1007 - Chemistry 3
- (2018) FAD1008 - Chemistry 4
- (2018) FAE1007 - Chemistry 1
SOCIAL RESPONSIBILITY ACTIVITIES
- Petugas Pameran Sempena Karnival Pendidikan Tinggi Negara (Kptn) 2018 Di Shah Alam, (31 Mar 2018 - 01 Apr 2018)
- Project With Secondary School Teachers and Students: Development of Scientist-Teacher-Student Partnership (Stsp) Model to Enchance Secondary Science Learning, (01 Feb 2016 - 30 Nov 2017)