Curriculum Vitae

DR. LIM JASMINE

Senior Lecturer
  • Department of Surgery
    Faculty of Medicine

AREAS OF EXPERTISE

ACADEMIC QUALIFICATION

  • PhD(Oxford University) (2011), (Clinical Laboraty Sciences)
    Oxford University, Oxford, Uk
  • BBMedSc(HONS)(UPM)(2006), (Biomedical Science)
    Universiti Putra Malaysia (UPM)

ADMINISTRATIVE DUTIES

  • Lab Manager
    01 Apr 2020 - 31 Mar 2021 (Faculty)
  • Coordinator
    07 Apr 2016 - 31 Mar 2018 (Faculty)

AWARD AND STEWARDSHIP

  • Leaders in Innovation Fellowships
    The Royal Academy of Engineering, 2020 (International)
  • First Place in The Royal Academy of Engineering's Leaders in Innovation Fellowships Final Pitch Session 2019/20
    The Royal Academy of Engineering, 2020 (International)
  • First Place in 3-minute Oral Presentation
    The 17th Urological Association of Asia Congress, 2019 (International)
  • GLOBAL INNOVATION THROUGH SCIENCE AND TECHNOLOGY TECH-I COMPETITION FINAL TOP 6 (IDEA CATEGORY)
    AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, 2019 (International)
  • Asian Universities Alliance (AUA) Scholars Award
    Asian Universities Alliance, 2018 (International)
  • Best Oral Presentation Award
    25th Malaysian Urological Conference, 2016 (International)
  • CERTIFICATE OF EXCELLENT SERVICE
    University of Malaya, 2015 (University)
  • Japan-Asia Youth Exchange Program in Science
    Japan Science and Technology Agency, 2015 (International)
  • Most number of participants in a 'cancer survivor' relay run campaign
    The Malaysia Book of Records, 2015 (National)
  • Best Oral Presentation Award
    23rd Malaysian Urological Conference Committee, 2014 (International)
  • NIHES/ESP Fellowship 2014
    NIHES?Erasmus Summer Program Organisation, Netherland Institute for Health Sciences, 2014 (International)
  • Sanofi-Aventis Prostate Cancer Research Award
    22nd Malaysian Urological Conference, 2013 (International)
  • Sanofi-Aventis Prostate Research Award
    21st Malaysian-Scottish Urological Conference Committee, 2012 (International)

PUBLICATIONS

Article in Journal
WoS
  1. Choy, Seow Huey; Nyanatay, Selina Ann; Sothilingam, Selvalingam; Malek, Rohan; Sathiyananthan, J. R.; Toh, Charng Chee; Sundram, Murali; Yusoff, Noor Ashani Md; Nagappan, Poongkodi; Kamaruzaman, Shakirin; Yeoh, Wei Sien; Ong, Teng Aik; Lim, Jasmine (2022). Cardiovascular risk factors, ethnicity and infection stone are independent factors associated with reduced renal function in renal stone formers, PLOS ONE. 17(4), . doi:10.1371/journal.pone.0265510
  2. Minh-Phuong Huynh-Le; Karunamuni, Roshan; Fan, Chun Chieh; Asona, Lui; Thompson, Wesley K.; Martinez, Maria Elena; Eeles, Rosalind A.; Kote-Jarai, Zsofia; Muir, Kenneth R.; Lophatananon, Artitaya; Schleutker, Johanna; Pashayan, Nora; Batra, Jyotsna; Groenberg, Henrik; Neal, David E.; Nordestgaard, Borge G.; Tangen, Catherine M.; MacInnis, Robert J.; Wolk, Alicja; Albanes, Demetrius; Haiman, Christopher A.; Travis, Ruth C.; Blot, William J.; Stanford, Janet L.; Mucci, Lorelei A.; West, Catharine M. L.; Nielsen, Sune F.; Kibel, Adam S.; Cussenot, Olivier; Berndt, Sonja, I; Koutros, Stella; Sorensen, Karina Dalsgaard; Cybulski, Cezary; Grindedal, Eli Marie; Menegaux, Florence; Park, Jong Y.; Ingles, Sue A.; Maier, Christiane; Hamilton, Robert J.; Rosenstein, Barry S.; Lu, Yong-Jie; Watya, Stephen; Vega, Ana; Kogevinas, Manolis; Wiklund, Fredrik; Penney, Kathryn L.; Huff, Chad D.; Teixeira, Manuel R.; Multigner, Luc; Leach, Robin J.; Brenner, Hermann; John, Esther M.; Kaneva, Radka; Logothetis, Christopher J.; Neuhausen, Susan L.; De Ruyck, Kim; Ost, Piet; Razack, Azad; Newcomb, Lisa F.; Fowke, Jay H.; Gamulin, Marija; Abraham, Aswin; Claessens, Frank; Castelao, Jose Esteban; Townsend, Paul A.; Crawford, Dana C.; Petrovics, Gyorgy; van Schaik, Ron H. N.; Parent, Marie-Elise; Hu, Jennifer J.; Zheng, Wei; Mills, Ian G.; Andreassen, Ole A.; Dale, Anders M.; Seibert, Tyler M. (2022). Prostate cancer risk stratification improvement across multiple ancestries with new polygenic hazard score, PROSTATE CANCER AND PROSTATIC DISEASES. (), . doi:10.1038/s41391-022-00497-7
  3. Huynh-Le, M. P., Fan, C. C., Karunamuni, R., Thompson, W. K., Martinez, M. E., Eeles, R. A., . . . Consortium, P. (2021). Polygenic hazard score is associated with prostate cancer in multi-ethnic populations. Nature communications, 12(1), 9. doi: 10.1038/s41467-021-21287-0
  4. Karunamuni, R. A., Huynh-Le, M. P., Fan, C. C., Thompson, W., Eeles, R. A., Kote-Jarai, Z., . . . Consortium, P. (2021). Additional SNPs improve risk stratification of a polygenic hazard score for prostate cancer. Prostate Cancer and Prostatic Diseases, 24(2), 532-541. doi: 10.1038/s41391-020-00311-2
  5. Lim, J., Onozawa, M., Saad, M., Ong, T. A., Malek, R., Akaza, H., . . . Study, M. C. M. P. C. (2021). Recent trend of androgen deprivation therapy in newly diagnosed prostate cancer patients: Comparing between high- and middle-income Asian countries. Cancer Science, 112(6), 2071-2080. doi: 10.1111/cas.14889
  6. Yap, X. L., Wood, B., Ong, T. A., Lim, J., Goh, B. H., & Lee, W. L. (2021). Detection of Prostate Cancer via IR Spectroscopic Analysis of Urinary Extracellular Vesicles: A Pilot Study. Membranes, 11(8), 19. doi: 10.3390/membranes11080591
  7. Lim, J., Hinotsu, S., Onozawa, M., Malek, R., Sundram, M., Teh, G. C., . . . Akaza, H. (2020). Modified J-CAPRA scoring system in predicting treatment outcomes of metastatic prostate cancer patients undergoing androgen deprivation therapy. Cancer Medicine, 9(24), 9346-9352. doi: 10.1002/cam4.3548
Others
  1. 1.Lim J, Malek R, JR S, Toh CC, Sundram M, Woo SYY, Yusoff NAM, Teh GC, Chui BJT, Ngu IS, Thevarajah S, Koh WJ, Lee SB, Khoo SC, Teoh BW, Zainal R, Tham TM, Omar S, Nasuha NA, Akaza H, Ong TA, M- CaP Study (2021). Prostate cancer in multi- ethnic Asian men: Real- world experience in the Malaysia Prostate Cancer (M- CaP) Study. Cancer Med. 00:1 9. doi:10.1002/cam4.4319.
  2. Amat, N., Philip, E.F., Chai, C.A., Yeoh, W.S., Lim, J., Fadzli, A.N., Kuppusamy, S. & Ong, T.A. (2021). The impact of population lockdown on the referral pattern for urology in a COVID-19 designated tertiary hospital in Malaysia. Urological Science, 32(1), 23-26.
  3. Conti DV, Darst DF, Moss LC, Saunders EJ, Sheng X, Chou A, Schumacher FR, Olama AAA, Benlloch S, Dadaev T, ......, Razack A, Lim J, Teo SH, et al (2021) Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. Nat Genet. 53(1):65-75. doi: 10.1038/s41588-020-00748-0
  4. Dasgupta R, Ong TA, Lim J, Rajandram R, Gao X, Hakim L, Mburugu P, Ajmera R, Yuruk E, Pu Y-S, Geavlete P, Azhar RA, Mutambirwa S, Baard J (2021). A Global Perspective of Stenting after Ureteroscopy: an Observational Multicenter Cohort Study. Soci t Internationale d'Urologie Journal 2 (2), 96 105
  5. Dee EC, Paguio JA, Yao JS, Lim J, Lasco G (2021). Correspondence on Asian minorities in Asian countries: intersecting disparities affecting minoritised groups. Lancet Oncol. e381. doi: 10.1016/S1470-2045(21)00350-8
  6. Brand o, A.; Paulo, P.; Maia, S.; Pinheiro, M.; Peixoto, A.; Cardoso, M.; Silva, M.P.; Santos, C.; Eeles, R.A.; Kote-Jarai, Z.; Muir, K.; UKGPCS Collaborators; Schleutker, J.; Wang, Y.; Pashayan, N.; Batra, J.; APCB BioResource; Gr nberg, H.; Neal, D.E.; Nordestgaard, B.G.; Tangen, C.M.; Southey, M.C.; Wolk, A.; Albanes, D.; Haiman, C.A.; Travis, R.C.; Stanford, J.L.; Mucci, L.A.; West, C.M.L.; Nielsen, S.F.; Kibel, A.S.; Cussenot, O.; Berndt, S.I.; Koutros, S.; S rensen, K.D.; Cybulski, C.; Grindedal, E.M.; Park, J.Y.; Ingles, S.A.; Maier, C.; Hamilton, R.J.; Rosenstein, B.S.; Vega, A.; The IMPACT Study Steering Committee and Collaborators; Kogevinas, M.; Wiklund, F.; Penney, K.L.; Brenner, H.; John, E.M.; Kaneva, R.; Logothetis, C.J.; Neuhausen, S.L.; Ruyck, K.D.; Razack, A.; Newcomb, L.F.; Canary PASS Investigators; Lessel, D.; Usmani, N.; Claessens, F.; Gago-Dominguez, M.; Townsend, P.A.; Roobol, M.J.; The Profile Study Steering Committee; The PRACTICAL Consortium; Teixeira, M.R. (2020) The CHEK2 Variant C.349A>G Is Associated with Prostate Cancer Risk and Carriers Share a Common Ancestor. Cancers. 12(11): 3254.
  7. Lim, J., Amantakul, A., Shariff, N., Lojanapiwat, B., Alip, A., Ong, T. A., Thevarajah, S., Ahmayuddin, F., Mathew, A., Sriplakich, S., Vuthiwong, J., Chong, F., & Saad, M. (2020). Clinical outcomes of abiraterone acetate and predictors of its treatment duration in metastatic castration-resistant prostate cancer: Real-world experience in the Southeast Asian cohort. Cancer medicine, 9(13), 4613 4621. https://doi.org/10.1002/cam4.3101
  8. Yii, R., Lim, J., Sothilingam, S., Yeoh, W. S., Fadzli, A. N., Ong, T. A., Kuppusamy, S., & Abdul Razack, A. H. (2020). Predictive factors of prostate cancer diagnosis with PSA 4.0-10.0 ng/ml in a multi-ethnic Asian population, Malaysia. Asian journal of surgery, 43(1), 87 94. https://doi.org/10.1016/j.asjsur.2019.02.014
  9. Anbarasen L, Lim J, Rajandram R, Mun KS, Sia SF (2019) Expression of osteopontin, matrix metalloproteinase-2 and -9 proteins in vascular instability in brain arteriovenous malformation. PeerJ 7:e7058 doi: 10.7717/peerj.7058
  10. Lojanapiwat B, Lee JY, Gang Z, Kim CS, Fai NC, Hakim L, Umbas R, Ong TA, Lim J, Letran JL, Chiong E, Lee SH, T rkeri L, Murphy DG, Moretti K, Cooperberg M, Carlie R, Hinotsu S, Hirao Y, Kitamura T, Horie S, Onozawa M, Kitagawa Y, Namiki M, Fukagai T, Miyazaki J, Akaza H. (2019) Report of the third Asian Prostate Cancer (A-CaP) Study Meeting. Prostate Int. 7(2): 60-67 doi: 10.1016/j.prnil.2018.06.001
  11. Mat, S., Razack, A.H., Lim, J., Khong, S.Y., Kamaruzzaman, S.B., Chin, A.V., Abbas, A.A., Hairi, N.N., Othman, S., Tan, M.P. (2019) Factors determining the increased risk of falls in individuals with knee pain in the Malaysian Elders Longitudinal Research (MELoR) Study. Frontiers in Medicine (Lausanne), 6, 277. doi: 10.3389/fmed.2019.00277
  12. Saad, M., Alip, A., Lim, J., Abdullah, M. M., Chong, F., Chua, C. B., Ismail, F., Khong, R. K., Lim, C. S., Loh, C. S., Malek, R., Mohd Ghani, K. A., Md Noor, I., Md Yusoff, N. A., Nasuha, N. A., Razack, A., Soo Hoo, H. F., Sundram, M., Tan, H. M., Thiagarajan, M., The, G. C., Voon, P. J., & Ong, T. A. (2019). Management of advanced prostate cancer in a middle-income country: real-world consideration of the Advanced Prostate Cancer Consensus Conference 2017. BJU international, 124(3), 373 382. https://doi.org/10.1111/bju.14807
  13. Tan JSJ, Ong KC, Ong DBL, Wu YS, Razack A, Kuppusamy S, Lim J, Rhodes A (2019) Polymorphisms in the androgen receptor CAG repeat sequence are related to tumour stage but not to ERG or androgen receptor expression in Malaysian men with prostate cancer. Malaysian J Pathol. 41 (3): 243 - 251
  14. Youl Lee, J., Taniguchi, T., Zhang, K., Ng, C. F., Hakim, L., Umbas, R., Kim, C. S., Chung, B. H., Kim, W. J., Aik Ong, T., Lim, J., & Akaza, H. (2019). Report of the forth Asian Prostate Cancer (A-CaP) study meeting. Japanese journal of clinical oncology, 49(6), 581 586. https://doi.org/10.1093/jjco/hyz053
  15. Dadaev, T., Saunders, E. J., Newcombe, P. J., Anokian, E., Leongamornlert, D. A., Brook, M. N., Cieza-Borrella, C., Mijuskovic, M., Wakerell, S., Olama, A., Schumacher, F. R., Berndt, S. I., Benlloch, S., Ahmed, M., Goh, C., Sheng, X., Zhang, Z., Muir, K., Govindasami, K., Lophatananon, A., Kote-Jarai, Z. (2018). Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants. Nature communications, 9(1), 2256. https://doi.org/10.1038/s41467-018-04109-8
  16. Lim, J., Rampal, S., Razack, A., Malek, R., Sundram, M., Nasuha, N. A., Ooi, C. C., Ong, T. A., & Sothilingam, S. (2018). A Novel Calculator for Estimating Prostate Volume in Daily Urology Services. Urology, 118, 145 151. https://doi.org/10.1016/j.urology.2018.02.055
  17. Schumacher, F. R., Al Olama, A. A., Berndt, S. I., Benlloch, S., Ahmed, M., Saunders, E. J., Dadaev, T., Leongamornlert, D., Anokian, E., Cieza-Borrella, C., Goh, C., Brook, M. N., Sheng, X., Fachal, L., Dennis, J., Tyrer, J., Muir, K., Lophatananon, A., Stevens, V. L., Gapstur, S. M., Genetic Associations and Mechanisms in Oncology (GAME-ON)/Elucidating Loci Involved in Prostate Cancer Susceptibility (ELLIPSE) Consortium (2018). Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. Nature genetics, 50(7), 928 936. https://doi.org/10.1038/s41588-018-0142-8
  18. Tan JSJ, Ong KC, Ong DBL, Razack A, Lim J, Yunus R, Sundram M, Rhodes A.(2018). Heterogenous expression of ERG oncoprotein in Malaysian men with adenocarcinoma of the prostate. Malays J Pathol. 40(2): 103-110.
  19. Kim, C. S., Lee, J. Y., Chung, B. H., Kim, W. J., Fai, N. C., Hakim, L., Umbas, R., Ong, T. A., Lim, J., Letran, J. L., Chiong, E., Wu, T. L., Lojanapiwat, B., T rkeri, L., Murphy, D. G., Gardiner, R. A., Moretti, K., Cooperberg, M., Carroll, P., Mun, S. K., Hinotsu, S., Hirao, Y., Ozono, S., Horie, S., Onozawa, M., Kitagawa, Y., Kitamura, T., Namiki, M., & Akaza, H. (2017). Report of the Second Asian Prostate Cancer (A-CaP) Study Meeting. Prostate international, 5(3), 95 103. https://doi.org/10.1016/j.prnil.2017.03.006
  20. Foong SF, Abdullah M, Lim J, Cheong SK, Seow HF. (2016) Subtractive Hybridization Identifies Stem Cell-Associated Genes in an Acute Myeloid Leukemia with Poor Prognosis. Malaysian Journal of Medicine and Health Sciences. 12(1): 19-31
  21. Lim, J., Bhoo-Pathy, N., Sothilingam, S., Malek, R., Sundram, M., Tan, G. H., Bahadzor, B., Ong, T. A., Ng, K. L., & Abdul Razack, A. H. (2015). Cardiovascular Risk Factors and Ethnicity Are Independent Factors Associated with Lower Urinary Tract Symptoms. PloS one, 10(6), e0130820. https://doi.org/10.1371/journal.pone.0130820
  22. Lim J, Bhoo-Pathy N, Sothilingam S, Malek R, Sundram M, Bahadzor BH, Ong TA, Ng KL, Sivalingam S, Abdul Razack AH (2014). Ethnicity is an independent determinant of age-specific PSA level: findings from a multiethnic Asian setting. PLoS ONE 9(8): e104917. doi:10.1371/journal.pone.0104917
  23. Lim J, Maher GJ, Turner GDH, Dudka-Ruszkowska W, Taylor S, Rajpert-De Meyts E, Goriely A, Wilkie AOM (2012). Selfish spermatogonial selection: evidence from an immunohistochemical screen in testes of elderly men. PLoS ONE 7(8): e42382. doi:10.1371/journal.pone.0042382
  24. Lim J, Goriely A, Turner GD, Ewen KA, Jacobsen GK, Graem N, Wilkie AO, Rajpert-De Meyts E. (2011). OCT2, SSX and SAGE1 reveal the phenotypic heterogeneity of spermatocytic seminoma reflecting distinct subpopulations of spermatogonia. J Pathol 224: 473-83.
  25. Goriely A, Lord H, Lim J, Johnson D, Lester T, Firth HV, Wilkie AO. (2010). Germline and somatic mosaicism for FGFR2 mutation in the mother of a child with Crouzon syndrome: Implications for genetic testing in "paternal age-effect" syndromes. Am J Med Genet A. 152A(8): 2067-73.

RESEARCH PROJECT

National
  1. 2017 - 2020, Malaysian National Insitute of Health (NIH) Grant
    Asia Study Group of Prostate Cancer Malaysian Cohort (M-CaP Study) ( Consultant)
  2. 2017 - 2017, Faculty of Medicine
    The 2nd ASEAN Student Project - A pilot study of exercise intervention in overweight and obese children ( Principal Investigator(PI))
  3. 2013 - 2016, High Impact Research (HIR)
    Pharmocogenomics of prostate cancer ( Consultant)
  4. 2012 - 2014, High Impact Research (HIR)
    Large-scale profiling of cancer/testis antigens (CTA) and the delineation of MiRNA-mediated reversal of CTA-associated aberrant demethylation in urothelial cell carcinoma ( Consultant)
  5. 2011 - 2013, Geran Penyelidikan Universiti Malaya (UMRG)
    Determining the prevalence of BPH and prostate cancer within community - a cross sectional study in Klang valley ( Consultant)
International
  1. 2016 - 2026, International Funding
    The Asian Prostate Cancer (A-CaP) Study ( Consultant)
  2. 2017 - 2022, International Funding
    A multi-national cohort study on the impact of intra-tumoural genomic heterogeneity and the immune micro-environment on the clinical trajectory of resected hepatocellular carcinoma. ( Consultant)

CONSULTANCY PROJECT

  • Endothelial Cells in Brain Arteriovenous Malformation (Avm), Australian School of Advanced Medicine, Macquarie University, Sydney
    01 Feb 2013 - 01 Feb 2016 (International)

TEACHING

Others
  1. (2014) DMLT1721 - Basic Histological Tecniques
  2. (2014) DMLT2723 - Histopathology 1
  3. (2014) DMLT3724 - Histopathology 2
  4. (2014) DMLT3725 - Cytology