Curriculum Vitae
BIOGRAPHY
Dr Jaime Jacqueline Jayapalan is a Senior Lecturer in the Department of Molecular Medicine at the Faculty of Medicine, Universiti Malaya (UM). She has extensive professional experience in academia and research, including visiting scholar positions in Sri Lanka and India.
Dr Jayapalan's academic journey began with a bachelor’s degree in biomedical science from the School of Health Sciences at Universiti Sains Malaysia, where she graduated with First Class honours in 2005. She then pursued a master’s degree in medical sciences from the Faculty of Medicine at UM (2009). Subsequently, she obtained a PhD in Biochemistry/ Proteomics (2015) and recently, a Master of Business Administration degree in Human Resource Management from the same institution (2021).
In addition to her academic pursuits, Dr Jayapalan has been actively involved in securing research grants and has successfully obtained funding from various sources. These grants have provided essential financial support for her research endeavours and have facilitated the advancement of scientific knowledge in her field. Notably, she received funding from the Ministry of Higher Education, Malaysia, for projects such as the identification of prostate cancer biomarkers, the exploration of predictors for early detection of cardiovascular changes in high-adiposity female adults, and the investigation of biochemical, metabolic, and proteomics changes in different phenotypes of pancreatic ductal adenocarcinoma. She has also been awarded scholar grants by the Asian Universities Alliance for her outstanding research contributions. With over 725 citations and an H-index of 16 according to Google Scholar, Dr. Jayapalan has made a significant impact on her field.
Dr Jayapalan's dedication to research, combined with her impressive academic credentials, publication record, and extensive funding success, establishes her as a prominent and respected figure in the field of molecular medicine. Her expertise and contributions have greatly advanced the understanding of cancer biomarkers and hold significant potential for improving diagnostic methods and treatment strategies in the future.
AREAS OF EXPERTISE
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PROTEOMIC TECHNOLOGIES: GEL BASED AND NON-GEL BASED PROTEOMICS, PROTEIN AND GLYCOPROTEIN EXPRESSION PROFILING, PROTEIN PURIFICATION.
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PROTEOMICS, GLYCOPROTEOMICS, URINOMICS: CANCER & DISEASE BIOMARKERS
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MASS SPECTROMETRY - MALDI TOF/TOF (PROTEIN IDENTIFICATION)
ACADEMIC QUALIFICATION
- MBA (Hons), (Business Administration)Universiti Malaya (UM)
- Ph.D, (Medicine)Universiti Malaya (UM)
- MMedSc (UM)(2009), (Medical Science)Universiti Malaya (UM)
- BHSc(Hons)(Biomedicine)(USM)(2005), (Science)Universiti Sains Malaysia (USM)
- Dip. Medical Laboratory Techhnology(USM)(2002), (Teknologi Makmal Perubatan)Universiti Sains Malaysia (USM)
ADMINISTRATIVE DUTIES
- Task Force Leader01 Jan 2023 - 31 Dec 2024 (Faculty)
- Committee Members01 Jan 2022 - 31 Dec 2023 (Faculty)
- Task Force Leader01 Apr 2022 - 31 Dec 2023 (Department)
- Task Force Leader04 Dec 2023 - 04 Dec 2023 (Faculty)
- Task Force Leader04 Sep 2023 - 10 Nov 2023 (University Malaya)
- Task Force Leader28 Oct 2022 - 27 Oct 2023 (Department)
- Coordinator18 Oct 2022 - 17 Oct 2023 (Department)
- Task Force Member09 Oct 2023 - 12 Oct 2023 (Department)
- AUDITOR BAGI EKSESAIS AUDIT KENDIRI FAKULTI PERUBATAN BIL. 1/202303 Jul 2023 - 15 Sep 2023 (Department of Molecular Medicine, Faculty of Medicine)
- Task Force Leader27 Jun 2023 - 27 Jun 2023 (University Malaya)
- Task Force Leader13 Jun 2023 - 13 Jun 2023 (Faculty)
- Task Force Leader08 Apr 2023 - 08 Apr 2023 (University Malaya)
- Task Force Leader27 Mar 2023 - 27 Mar 2023 (Faculty)
- Task Force Member09 Feb 2023 - 09 Feb 2023 (University Malaya)
- Task Force Member07 Feb 2023 - 07 Feb 2023 (University Malaya)
- Approved Signatory MS ISO/IEC 17025:201701 Jan 2020 - 31 Dec 2022 (National)
- Committee Members24 Feb 2022 - 31 Dec 2022 (Department)
- Ahli Tetap Seminar Proposal Defence01 Jan 2020 - 31 Dec 2022 (Faculty)
- Ahli Jawatankuasa Sewa Peralatan22 Jul 2020 - 22 Jul 2022 (Department of Molecular Medicine, Faculty of Medicine)
- Committee Members01 Jul 2021 - 30 May 2022 (Department of Molecular Medicine, Faculty of Medicine)
- Committee Member Research Communication Unit01 Apr 2020 - 31 Dec 2021 (Faculty)
- Ahli Jawatankuasa Spesifikasi perolehan perkhidmatan pembelian bawah RM50K24 Sep 2021 - 24 Oct 2021 (Department of Molecular Medicine, Faculty of Medicine)
- Assistant Deputy Quality Manager01 Jul 2019 - 30 Jun 2021 (Department of Molecular Medicine, Faculty of Medicine)
- AJK Research & International Collaboration22 Apr 2019 - 21 Apr 2021 (Department of Molecular Medicine, Faculty of Medicine)
- Invigilator Professional Examination 2019/2020, Faculty of Dentistry, UM, July 2020.06 Aug 2020 - 06 Aug 2020 (Faculty)
- Pemeriksa Dalam Peperiksaan Profesional Ijazah Sarjana Muda Pembedahan Pergigian 2019/202006 Mar 2020 - 05 Aug 2020 (Faculty)
- Assistant Coordinator for Faculty Elective Course01 Jul 2019 - 30 Jun 2020 (Department of Molecular Medicine, Faculty of Medicine)
- Working committee for Journal of Research Management and Governance01 Nov 2017 - 31 Oct 2019 (University Malaya)
- Panel Penilai Seminar Proposal Defence - MMedSc31 Jul 2019 - 31 Jul 2019 (Department of Molecular Medicine, Faculty of Medicine)
- Chairperson, Specification & Technical Evaluation and Evaluation of Quotation for Procurement for UMCIC, UM.28 Dec 2018 - 28 Jan 2019 (University Malaya)
- Technical Manager/Resource Person: Accreditation ISO/IEC MS17025:200501 Jan 2016 - 31 Dec 2018 (University Malaya)
- Jawatankuasa induk audit makmal fakulti perubatan28 Oct 2018 - 02 Nov 2018 (Faculty)
- Ahli jawatankuasa penilaian sebutharga06 Aug 2018 - 29 Aug 2018 (Dean Office, Faculty of Medicine)
- Pegawai Rekod Pusat24 Nov 2016 - 31 Dec 2017 (Dean Office, Faculty of Medicine)
- Rapporteur15 Aug 2016 - 07 Oct 2016 (University Malaya)
- Technical Manager/Resource Person: Accreditation ISO/IEC MS17025:200507 Apr 2014 - 31 Dec 2015 (University Malaya)
- Auditor: Audit Dalaman Kualiti ISO/IEC 1702501 Dec 2015 - 16 Dec 2015 (University Malaya)
- Facilitator: CRL Open Day 201505 Oct 2015 - 05 Oct 2015 (University Malaya)
- Auditor: Audit Dalaman Kualiti ISO/IEC 1702529 Jun 2015 - 08 Jul 2015 (University Malaya)
- Organising Committee Member: Biotech Open Day 201313 Nov 2013 - 13 Nov 2013 (University Malaya)
- Organising Committee Member: Proteomics Symposium 201323 Jan 2013 - 23 Jan 2013 (University Malaya)
- Organising Committee Member: UMCPR Research Day cum Proteomics Workshop21 Jun 2012 - 21 Jun 2012 (University Malaya)
- Auditor: Audit Ruang Makmal28 Nov 2011 - 01 Dec 2011 (University Malaya)
MEMBERSHIPS
- PULSE@UM MAGAZINE, EDITORIAL BOARD2023 to 2024 (University)
- MALAYSIAN PROTEOMICS SOCIETY, TREASURER2022 to 2024 (National)
- LIFETIME MEMBERSHIP - MALAYSIAN PROTEOMICS SOCIETY, MEMBERSince 2022 (National)
- LIFE MEMBER - MALAYSIAN SOCIETY FOR BIOCHEMISTRY & MOLECULAR BIOLOGY (MSBMB), MEMBERSince 2022 (National)
- ORGANIZATION FOR WOMEN IN SCIENCE FOR THE DEVELOPING WORLD (OWSD), MEMBERSince 2021 (International)
- LIFETIME MEMBER, MEMBERSince 2003 (International)
- SCIEX INNOVATION ADVISORY BOARD, ADVISORY BOARD2021 to 2021 (International)
- MALAYSIAN AGRICULTURAL PROTEOMICS SOCIETY , MEMBER2019 to 2021 (National)
- MALAYSIAN SOCIETY FOR BIOCHEMISTRY & MOLECULAR BIOLOGY, MEMBER2016 to 2021 (National)
- SM JOURNAL OF BIOINFORMATICS AND PROTEOMICS, EDITORIAL BOARD MEMBER2016 to 2017 (International)
- OPEN JOURNAL OF PROTEOMICS, EDITORIAL BOARD MEMBER2016 to 2017 (International)
AWARD AND STEWARDSHIP
- 2022 ACS PUBLICATIONS PEER REVIEWER CERTIFICATE OF RECOGNITION & APPRECIATIONACS Publications, 2023 (International)
- AUA Scholars AwardTsinghua University, Beijing, China, 2022 (International)
- EXCELLENCE SERVICE AWARDUniversity of Malaya, 2022 (University)
- Reviewer Certificate of Appreciation: Cancer Medicine year 2020WILEY, 2021 (International)
- Panel of Jury - 3 Minute Thesis (3MT) Research Methodology CourseFoM, UM, 2020 (Ptj/ Faculty)
- Excellent PBL Facilitation for Block Haematology, University of Malaya Medical Programme, Stage 2, Session 2020/ 2021MERDU, FoM,UM, 2020 (Ptj/ Faculty)
- Excellent PBL Facilitation, Block Cardiovascular Sciences, University of Malaya Medical Programme, Stage 1, Session 2019/2020MERDU, FoM,UM, 2020 (Ptj/ Faculty)
- 2019 Innovation Advisory BoardSCIEX, 2020 (International)
- Excellent PBL Facilitation for Block 9 Urology, University of Malaya Medical Programme, Stage 2, Session 2019/ 2020MERDU, FoM, 2020 (Ptj/ Faculty)
- Outstanding Women in Health & Medical SciencesVenus International Foundation, 2020 (International)
- Excellent PBL Facilitation for Block Haematology Session 2019/2020Merdu, FoM, 2019 (Ptj/ Faculty)
- Best Poster Award - 27th FAOBMB & 44th MSBMB ConferenceFAOBMB & MSBMB , 2019 (International)
- Appreciation for Reviewer for Electrophoresis by ElectrophoresisWiley - Electrophoresis, 2019 (International)
- Malaysia Agricultural Proteomics Society (MAPS) Travel Award 2019Malaysia Agricultral Proteomics Society (MAPS) , 2019 (National)
- SCIEX Innovation Advisory Board Team 2018SCIEX, 2019 (International)
- 3rd position quiz winner, Big Data, Bioinformatics & Proteomics WorkshopIITB, Mumbai 2019, 2019 (International)
- AUA Scholar AwardAsean Universities Alliances , 2018 (International)
- SCIEX Innovation Advisory Board TeamSciex, 2017 (International)
- ANUGERAH CEMERLANG UNIVERSITY MALAYA 2017 EXCELLENT MANAGEMENT & PROFESSIONAL STAFFUNIVERSITI MALAYA, 2017 (University)
- Sustainability Lens: Photo CompetitionSustainability Science Research Cluster, University of Malaya, 2016 (University)
- Anugerah Khas Perkhidmatan CemerlangUniversity of Malaya, 2014 (University)
- Recipient of Conference Sponsorship - 14th Congress of the ASEAN Federation of Endocrine SocietiesGlaxoSmithKline Pharmaceutical Sdn. Bhd., 2007 (Private)
- Bronze medal- Research, Invention & Innovation Exposition, UMUniversity of Malaya, 2007 (University)
- Recipient of 'Skim Pasca Siswazah' ScholarshipUM, 2006 (University)
- Book Prize - BHSc (Hons)University of Science Malaysia, 2005 (University)
- Gold Medal - DipMLTUniversity Science Malaysia, 2002 (University)
PUBLICATIONS
Article in Journal
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Krishnan, Illayaraja; Chan, Alvin Man Lung; Law, Jia Xian; Ng, Min Hwei; Jayapalan, Jaime Jacqueline; Lokanathan, Yogeswaran (2024). Proteomic Analysis of Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles: A Systematic Review, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 25(10). doi:10.3390/ijms25105340
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Vellan, Christina Jane; Islam, Tania; De Silva, Sumadee; Taib, Nur Aishah Mohd; Prasanna, Galhena; Jayapalan, Jaime Jacqueline (2024). Exploring novel protein-based biomarkers for advancing breast cancer diagnosis: A review, CLINICAL BIOCHEMISTRY. 129. doi:10.1016/j.clinbiochem.2024.110776
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Pantong, Wanita; Pederick, Jordan L.; Maenpuen, Somchart; Tinikul, Ruchanok; Jayapalan, Jaime J.; Jovcevski, Blagojce; Wegener, Kate L.; Bruning, John B.; Salaemae, Wanisa (2023). Biochemical and structural characterization of meningococcal methylenetetrahydrofolate reductase, PROTEIN SCIENCE. 32(6). doi:10.1002/pro.4654
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Wong, Kar-Cheng; Jayapalan, Jaime J.; Subramanian, Perumal; Ismail, Mohd Nazri; Abdul-Rahman, Puteri S. (2023). Label-free quantitative mass spectrometry analysis of the circadian proteome of Drosophila melanogaster lethal giant larvae mutants reveals potential therapeutic effects of melatonin, ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY. . doi:10.1002/arch.22008
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Vellan, Christina Jane; Jayapalan, Jaime Jacqueline; Yoong, Boon-Koon; Abdul-Aziz, Azlina; Mat-Junit, Sarni; Subramanian, Perumal (2022). Application of Proteomics in Pancreatic Ductal Adenocarcinoma Biomarker Investigations: A Review, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 23(4). doi:10.3390/ijms23042093
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Subramanian, P., Jayapalan, J. J., & Abdul-Rahman, P. S. (2021). Cancer Proteomics: New Horizons and Insights into Therapeutic Applica-tions. Current Proteomics, 18(3), 266-278. doi: 10.2174/1570164617666200814153949
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Subramanian, P; Jayapalan, JJ; Abdul-Rahman, PS (2021). Inevitable interlinks between biological clock and metabolism in mammals, BIOLOGICAL RHYTHM RESEARCH. . doi:10.1080/09291016.2021.1928386
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Teh, A. L. D., Jayapalan, J. J., Loke, M. F., Kadir, A., & Subrayan, V. (2021). Identification of potential serum metabolic biomarkers for patient with keratoconus using untargeted metabolomics approach. Experimental Eye Research, 211, 10. doi: 10.1016/j.exer.2021.108734
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Wong, K. C., Sankaran, S., Jayapalan, J. J., Subramanian, P., & Abdul-Rahman, P. S. (2021). Melatonin improves cognitive behavior, oxidative stress, and metabolism in tumor-prone lethal giant larvae mutant of Drosophila melanogaster. Archives of Insect Biochemistry and Physiology, 107(1), 20. doi: 10.1002/arch.21785
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Adenan, D. M., Jaafar, Z., Jayapalan, J. J., & Aziz, A. A. (2020). Plasma antioxidants and oxidative stress status in obese women: correlation with cardiopulmonary response. PeerJ, 8, 22. doi: 10.7717/peerj.9230
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Adenan, DM; Jaafar, Z; Jayapalan, JJ; Aziz, AA (2020). Plasma antioxidants and oxidative stress status in obese women: correlation with cardiopulmonary response, PEERJ. 8. doi:10.7717/peerj.9230
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Jayapalan, J. J., Subramanian, P., Kani, A., Hiji, J., Najjar, S. G., Abdul-Rahman, P. S., & Hashim, O. H. (2020). Hesperidin modulates the rhythmic proteomic profiling inDrosophila melanogasterunder oxidative stress. Archives of Insect Biochemistry and Physiology, 105(3), 37. doi: 10.1002/arch.21738
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Nasir, N. M., Hiji, J., Jayapalan, J. J., Hashim, O. H. (2020). Potential use of human hair shaft keratin peptide signatures to distinguish gender and ethnicity. PeerJ, 8, 15. doi: 10.7717/peerj.8248
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Nasir, NM; Hiji, J; Jayapalan, JJ; Hashim, OH (2020). Potential use of human hair shaft keratin peptide signatures to distinguish gender and ethnicity, PEERJ. 8. doi:10.7717/peerj.8248
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Abdullah, M. I., Junit, S. M., Ng, K. L., Jayapalan, J. J., Karikalan, B., Hashim, O. H. (2019). Papillary Thyroid Cancer: Genetic Alterations and Molecular Biomarker Investigations. International Journal of Medical Sciences, 16(3), 450-460. doi:10.7150/ijms.29935
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Abdullah, Mardiaty Iryani; Junit, Sarni Mat; Ng, Khoon Leong; Jayapalan, Jaime Jacqueline; Karikalan, Barani; Hashim, Onn Haji (2019). Papillary Thyroid Cancer: Genetic Alterations and Molecular Biomarker Investigations, INTERNATIONAL JOURNAL OF MEDICAL SCIENCES. 16(3), 450-460. doi:10.7150/ijms.29935
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Anada, Raj Poovindran; Wong, Kum Thong; Jayapalan, Jaime Jacqueline; Hashim, Onn Haji; Ganesan, Dharmendra (2018). Panel of serum protein biomarkers to grade the severity of traumatic brain injury, ELECTROPHORESIS. 39(18), 2308-2315. doi:10.1002/elps.201700407
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Arumugam, M; Jayapalan, JJ; Abdul-Rahman, PS; Hashim, OH; Subramanian, P (2018). Effect of hesperidin on the temporal regulation of redox homeostasis in clock mutant (Cry(b)) of Drosophila melanogaster, BIOLOGICAL RHYTHM RESEARCH. 49(1), 93-102. doi:10.1080/09291016.2017.1333567
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Jayapalan, Jaime Jacqueline; Lee, Cheng-Siang; Lee, Ching Chin; Ng, Khoon Leong; Junit, Sarni Mat; Hashim, Onn Haji (2018). iTRAQ analysis of urinary proteins: Potential use of gelsolin and osteopontin to distinguish benign thyroid goiter from papillary thyroid carcinoma, CLINICAL BIOCHEMISTRY. 53, 127-131. doi:10.1016/j.clinbiochem.2018.01.008
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Lim, C. Y., Junit, S. M., Aziz, A. A., Jayapalan, J. J., Hashim, O. H. (2018). The hypolipidemic effects of Tamarindus indica fruit pulp extract in normal and diet-induced hypercholesterolemic hamsters are associated with altered levels of serum proteins. Electrophoresis, 39(23), 2965-2973. doi:10.1002/elps.201800258
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Lim, Chor Yin; Junit, Sarni Mat; Aziz, Azlina Abdul; Jayapalan, Jaime Jacqueline; Hashim, Onn Haji (2018). The hypolipidemic effects of Tamarindus indica fruit pulp extract in normal and diet-induced hypercholesterolemic hamsters are associated with altered levels of serum proteins, ELECTROPHORESIS. 39(23), 2965-2973. doi:10.1002/elps.201800258
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Hashim, OH; Jayapalan, JJ; Lee, CS (2017). Lectins: an effective tool for screening of potential cancer biomarkers, PEERJ. 5. doi:10.7717/peerj.3784
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Ramli, Nur Siti Fatimah; Junit, Sarni Mat; Ng, Khoon Leong; Razali, Nurhanani; Jayapalan, Jaime Jacqueline; Aziz, Azlina Abdul (2017). Analyses of antioxidant status and nucleotide alterations in genes encoding antioxidant enzymes in patients with benign and malignant thyroid disorders, PEERJ. 5. doi:10.7717/peerj.3365
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Subramanian, P; Kaliyamoorthy, K; Jayapalan, JJ; Abdul-Rahman, PS; Hashim, OH (2017). Influence of Quercetin in the Temporal Regulation of Redox Homeostasis in Drosophila melanogaster, JOURNAL OF INSECT SCIENCE. 17(2). doi:10.1093/jisesa/iex040
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Subramanian, P., Anandan, R., Jayapalan, J. J., Hashim, O. H. (2015). Hesperidin protects gentamicin-induced nephrotoxicity via Nrf2/HO-1 signaling and inhibits inflammation mediated by NF-kappa B in rats, Journal of Functional Foods. 13, 89-99
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Subramanian, P., Jayakumar, M., Singaravel, M., Kumar, D., Basu, P., Jayapalan, J. J., Hashim, O. H. (2015). Fisetin, a dietary flavonoid, attenuates hyperammonemia and improves circadian locomotor deficits, redox balance, and astrocytic markers in rats, Journal of Functional Foods. 12, 409-419
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Al-Obaidi, J. R., Mohd-Yusuf, Y., Razali, N., Jayapalan, J. J., Tey, C. C., Md-Noh, N., Junit, S. M., Othman, R. Y., Hashim, O. H. (2014). Identification of Proteins of Altered Abundance in Oil Palm Infected with Ganoderma boninense, International Journal of Molecular Sciences. 15(3), 5175-51921422-0067.
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Jessie, K., Jayapalan, J. J., Rahim, Z. H. A., Hashim, O. H. (2014). Aberrant proteins featured in the saliva of habitual betel quid chewers: An indication of early oral premalignancy?, Electrophoresis. 35(24), 3504-3511
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Subramanian, P., Jayakumar, M., Jayapalan, J. J., Hashim, O. H. (2014). Chronotherapeutic effect of fisetin on expression of urea cycle enzymes and inflammatory markers in hyperammonaemic rats, Pharmacological Reports. 66(6), 1037-1042
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Subramanian, P., Jayapalan, J. J., Hashim, O. H. (2014). Chronotherapy: a noteworthy focal point in the treatment of cancer?, Biological Rhythm Research. 45(5), 709-729
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Subramanian, P., Prasanna, V., Jayapalan, J. J., Rahman, P. S. A., Hashim, O. H. (2014). Role of Bacopa monnieri in the temporal regulation of oxidative stress in clock mutant (cry(b)) of Drosophila melanogaster, Journal of Insect Physiology. 65, 37-44
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Verma, D., Hashim, O. H., Jayapalan, J. J., Subramanian, P. (2014). Effect of melatonin on antioxidant status and circadian activity rhythm during hepatocarcinogenesis in mice, Journal of Cancer Research and Therapeutics. 10(4), 1040-1044
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Abdelwahab, S. I., Taha, M. M. E., Abdulla, M. A., Nordin, N., Hadi, A. H. A., Mohan, S., Jayapalan, J. J., Hashim, O. H. (2013). Gastroprotective mechanism of Bauhinia thonningii Schum, Journal of Ethnopharmacology. 148(1), 277-286
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Jayapalan, J. J., Ng, K. L., Shuib, A. S., Razack, A. H. A., Hashim, O. H. (2013). Urine of patients with early prostate cancer contains lower levels of light chain fragments of inter-alpha-trypsin inhibitor and saposin B but increased expression of an inter-alpha-trypsin inhibitor heavy chain 4 fragment, Electrophoresis. 34(11), 1663-1669
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Jessie, K., Jayapalan, J. J., Ong, K. C., Abdul Rahim, Z. H., Zain, R. M., Wong, K. T., Hashim, O. H. (2013). Aberrant proteins in the saliva of patients with oral squamous cell carcinoma, Electrophoresis. 34(17), 2495-2502
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Ismail F., Junit S.M., Chin L.C., Jayapalan J.J., Subrayan V. (2024). Association of ARMS2, HTRA1 and CFH genes polymorphisms in patients with age-related macular degeneration in the Malaysian population, Egyptian Journal of Medical Human Genetics. 25(1). doi:10.1186/s43042-024-00549-8
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Amulya, L. S., Subramanian, P., Jayapalan, J. J., Abdul Rahman, P. S. Effect of Indian snake (Naja naja) venom on cognition and biochemical indices in yellow mutant of Drosophila melanogaster treated with N-nitrosodiethylamine. Int J Entomol Res 2023, 8(2): 76-84.
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Amulya, L. S., Subramanian, P., Jayapalan, J. J., Abdul Rahman, P. S. Effect of Indian snake (Naja naja) venom on cognition and biochemical indices in yellow mutant of Drosophila melanogaster treated with N-nitrosodiethylamine. Int J Entomol Res 2023, 8(2): 76-84.
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Taha M. M. E., Abdelwahab S. I., Mariod A., Abdulla M. A., Nordin N., Jayapalan J. J., Hashim O. H. Stem bark methanolic extract of Bauhinia thonningii (Schum) demonstrates gastroprotective properties against in vivo ethanol-induced injury. Func Food Sci 2023, 3(4): 26-40, DOI: 10.31989/ffs.v3i4.1048.
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Subramanian, P, Jayapalan, J. J., Abdul-Rahman, P. S. Cancer proteomics: New horizons and insights into therapeutic applications. Curr Proteomics (2020) 17: 1. DOI:10.2174/1570164617666200814153949.
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Wong, K. C., Sankaran, S., Jayapalan, J. J., Subramanian, P., & Abdul-Rahman, P. S. (2021). Melatonin improves cognitive behavior, oxidative stress, and metabolism in tumor-prone lethal giant larvae mutant of Drosophila melanogaster. Archives of insect biochemistry and physiology, 107(1), e21785. https://doi.org/10.1002/arch.21785
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Adenan, D. M., Jaafar, Z., Jayapalan, J. J., Abdul Aziz, A. Plasma antioxidants and oxidative stress status in obese women: Correlation with cardiopulmonary response. PeerJ 2020 8:e9230. DOI: 10.7717/peerj.9230
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Mohamed Nasir, N., Hiji, J., Jayapalan, J. J., Hashim, O.H. (2019). Potential use of human hair shaft keratin peptide signatures to distinguish gender and ethnicity. PeerJ.
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Abdullah, M. I., Junit, S. M., Ng, K. L., Jayapalan, J. J., Karikalan, B., Hashim, O. H. Papillary thyroid cancer: Genetic alterations and molecular biomarker investigations.
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Anada R, Wong KT, Jayapalan JJ, Hashim OH, Ganesan D. Panel of serum protein biomarkers to grade the severity of traumatic brain injury. Electrophoresis. 2018. Doi: 10.1002/elps.201700407
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Arumugam, M., Jayapalan, J. J., AbdulRahman, P. S., Hashim, O. H. and Subramanian, P. (2018) Effect of hesperidin on the temporal regulation of redox homeostasis in clock mutant (Cryb) of Drosophila melanogaster. Biol Rhythm Res 49(1): 93-102.
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JJ Jayapalan, et al (2018 ) iTRAQ analysis of urinary proteins: Potential use of gelsolin and osteopontin to distinguish benign thyroid goiter from papillary thyroid carcinoma. Clinical Biochemistry, 53 (2018) 127-131
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Lim CY, Junit SM, Aziz AA, Jayapalan JJ, Hashim OH. (2018). The hypolipidemic effects of Tamarindus indica fruit pulp extract in normal and diet induced hypercholesterolemic hamsters are associated with altered levels of serum proteins. Electrophoresis, doi: 10.1002/elps.201800258.
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Hashim OH, Jayapalan JJ, Lee C. (2017) Lectins: an effective tool for screening of potential cancer biomarkers. PeerJ 5:e3784.
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Nur Siti Fatimah Ramli, Sarni Mat Junit, Ng Khoon Leong, Nurhanani Razali, Jaime Jacqueline Jayapalan and Azlina Abdul Aziz. (2016). Analyses of antioxidant status and nucleotide alterations in genes encoding antioxidant enzymes in patients with benign and malignant thyroid disorders. PeerJ (Accepted).
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Subramanian, P. , Kaliyamoorthy, K., Jayapalan, J. J. Abdul-Rahman, P. S., Hashim, O. H. (2017). Influence of quercetin in the temporal regulation of redox homeostasis in Drosophila melanogaster. J Insect Sci 17(2): 1 11.
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Subramanian P, Jayapalan JJ, Abdul-Rahman PS, Arumugam M, Hashim OH (2016) Temporal regulation of proteome profile in the fruit fly, Drosophila melanogaster. PeerJ, 4, e2080.
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Perumal Subramanian, Ramaswamy Anandan, Jaime Jacqueline Jayapalan, Onn Haji Hashim, Hesperidin protects gentamicin-induced nephrotoxicity via Nrf2/HO-1 signaling and inhibits inflammation mediated by NF- B in rats, Journal of Functional Foods, Volume 13, March 2015, Pages 89-99, ISSN 1756-4646, http://dx.doi.org/10.1016/j.jff.2014.12.035.
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Subramanian, P., Jayakumar, M., Singaravel, M., Kumar, D., Basu, P., Jayapalan, J. J., Hashim, O. H. (2015) Fisetin, a dietary flavonoid, attenuates hyperammonemia and improves circadian locomotor deficits, redox balance, and astrocytic markers in rats. J. Func. Foods 12: 405-419.
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Al-Obaidi, J. R., Mohd-Yusuf, Y., Razali, N., Jayapalan, J. J., Tey, C. C., Md-Noh, N., Mat Junit, S., Othman, R. Y., Hashim, O. H., (2014). Identification of proteins of altered abundance in oil palm infected with Ganoderma boninense. Int J Mol Sci, 15(3): 5175 5192.
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Subramanian, P., Jayakumar, M., Jayapalan, J. J. & Hashim, O. H. (2014). Chronotherapeutic effect of fisetin on expression of urea cycle enzymes and inflammatory markers in hyperammonaemic rats. Pharmacological Reports, 66(6), 1037-1042.
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Subramanian, P., Prasanna, V., Jayapalan, J.J. and Abdul- Rahman, P.S., Hashim, O.H., (2014) Role of Bacopa monnieri in the temporal regulation of oxidative stress in clock mutant (cryb) of Drosophila melanogaster. Journal of Insect Physiology, 65, 37-44.
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Verma, D., Hashim, O., Jayapalan, J. J., Subramanian, P., Effect of melatonin on antioxidant status and circadianactivity rhythm during hepatocarcinogenesis in mice. J Cancer Res Ther 2014, 10(4): 1040-1044.
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Abdelwahab, S.I., Taha, M. M. E, Abdulla, M. A., Nordin, N., Hadi, A. H. A., Mohan, S., Jayapalan, J. J. and Hashim, O. H. (2013) Gastroprotective mechanism of Bauhinia thonningii Schum. Journal of Ethnopharmacology, 148, 277-286.
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Jayapalan, J.J., Ng, K. L., Shuib, A. S., Razack, A. H., Hashim, O. H., (2013) Urine of patients with early prostate cancer contains lower levels of light chain fragments of inter-alpha-trypsin inhibitor and saposin B but increased expression of an inter-alpha-trypsin inhibitor heavy chain 4 fragment. Electrophoresis 2013, 34 (11),
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Jessie, K., Jayapalan, J. J., Ong, K. C., Abdul Rahim, Z. H., Zain, R. M., Wong, K. T., Hashim, O. H., Aberrant proteins in the saliva of patients with oral squamous cell carcinoma. Electrophoresis 2013, 34 (17), 2495-502.
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Mohamed, E., Jayapalan, J.J., Abdul-Rahman, P., Omar, S., Hashim, O., Enhanced expression of a 35kDa fragment of inter-alpha-trypsin inhibitor H4 in sera of healthy pregnant women and patients with hydatidiform mole. Biomarker Research 2013, 1 (1), 19.
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Jayapalan, J.J., Ng, K. L., Razack, A. H., Hashim, O. H., (2012) Identification of potential complementary serum biomarkers to differentiate prostate cancer from benign prostatic hyperplasia using gel- and lectin-based proteomics analyses. Electrophoresis 2012, 33 (12), 1855-62.
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Jayapalan, J. J., Muniandy, S., Chan, S. P., (2010) Angiotensin converting enzyme insertion/deletion gene polymorphism: An observational study among diabetic hypertensive subjects in Malaysia. Trop J Pharm Res 2010, 9 (5), 431- 439.
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Jayapalan, J. J., Muniandy, S., Chan, S. P., Null association between ACE gene I/D polymorphism and diabetic nephropathy among multiethnic Malaysian subjects. Indian J Hum Genet 2010, 16 (2), 78-86.
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Seriramalu, R., Pang, W. W., Jayapalan, J. J., Mohamed, E., Abdul-Rahman, P. S., Bustam, A. Z., Khoo, A. S., Hashim, O. H., (2010) Application of champedak mannose-binding lectin in the glycoproteomic profiling of serum samples unmasks reduced expression of alpha-2 macroglobulin and complement factor B in patients with nasopharyngeal carcinoma. Electrophoresis 2010, 31 (14), 2388-95.
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Jayapalan, J. J., Muniandy, S., Chan, S. P., Angiotensin- 1 converting enzyme I/D gene polymorphism: scenario in Malaysia. SE Asian J Trop Med 2008, 39 (5), 917-21.
Article in Proceeding
- Subramanian, P., Jayapalan J. J., & Abdul Rahman, P. S. (2023, January 7 - 9). Oxidative stress and circadian regulation of proteome profile in Drosophila melanogaster: Protective influences of hesperidin. Proceedings of the International Conference on Molecular Medicine and Therapeutics (pp.22). Department of Biochemistry & Biotechnology, Annamalai University, India.
- Jayapalan, J. J., Hiji, J., Tan, A. H. (2021, 1- 3 June). Comparative proteomics profiling of serum of women with BIRADS scores of 1 to 5 using gel-based approaches. Proceedings of the 4th International Conference on Molecular Biology and Biotechnology 2021 (ICMBB2021), Virtual Conference. AsPac J. Mol. Biol. Biotechnol. 2021, Vol. 29 (2) Suppl:118.
- Ng, J. B., Jayapalan, J. J., Ong, K. C., Rozaida Poh, Y. Y. (2021, 1- 3 June). Differential lipocalin-1 levels in keratoconus in a Malaysian cohort. Proceedings of the 4th International Conference on Molecular Biology and Biotechnology 2021 (ICMBB2021), Virtual Conference. AsPac J. Mol. Biol. Biotechnol. 2021, Vol. 29 (2) Suppl:80.
- Wong, K.C., Jayapalan, J. J., Subramanian, P., Abdul-Rahman, P. S. (2021, 1-3 June) Proteomic analysis reveals protective role of melatonin in tumour-prone Drosophila melanogaster lethal giant larvae mutants. Proceedings of the 4th International Conference on Molecular Biology and Biotechnology 2021 (ICMBB2021), Virtual Conference. AsPac J. Mol. Biol. Biotechnol. 2021, Vol. 29 (2) Suppl:67.
- Jayapalan, J. J., Mokhtar, M. F., Hiji, J., Aziz, A. A., Junit, S. M., Zaini, A. A., Jalaludin, M. Y., Hashim, O. H. Identification of potential urine biomarkers for children with precocious puberty using gel-based proteomic approach. Malay J Biochem Mol Biol 2018.
- Jayapalan, J. J., Serum and urine inter-alpha-trypsin inhibitor peptides: A potential biomarker for differentiating cancer from benign prostate. Malay J Biochem Mol Biol 2017, In press.
- Jayapalan JJ, Hashim OH, Subramanian P. (2016) Temporal regulation of protein expression in drosophila melanogaster. Malay J Biochem Mol Biol 19 (3):42.
- Jayapalan JJ, Ng KL, Razack AHA, Hashim OH. Potential use of reciprocal levels of serum and urinary peptides for discriminating prostate cancer from benign prostatic hyperplasia. J Proteomics Bioinform 2016, 9:11 (Suppl).
- The use of urinary inter-alpha trypsin inhibitor peptides as biomarkers to discriminate benign prostatic hyperplasia from prostate cancer, 2nd International Caparica Conference on Urinomics and Translational Nephrology, 28 Sep 2015 to 30 Sep 2015, (International)
- Jayapalan JJ, Ng KL, Razack AHA, Hashim OH. Serum and urinary inter-alpha trypsin inhibitor peptides as biomarkers for prostate cancer. International Journal of Molecular Medicine. 2014;34:S36-S36.
- Jayapalan, J. J., Abdul Rahman, P. S., Ng, K. L., Razack, A. H., Hashim, O. H., Lectin-based glycoproteomic profiling of serum samples from patients with prostate cancer. 31st Congress of the Society Internationale d'Urologie, Berlin, Germany, 16th - 20th Oct 2011. Proceedings published in Urology, 2011; Vol 78 (Supplement 3A).
RESEARCH PROJECT
National
- 2022 - 2025, Fundamental Research Grant Scheme (FRGS)Mass Spectrometric and Immunohistochemical Profiling of Stage-Specific N- And O-Glycans for The Identification of Prostate Cancer Biomarker ( Co-Researcher)
- 2020 - 2024, Fundamental Research Grant Scheme (FRGS)Elucidating The Predictors For Early Detection Of Subclinical Cardiovascular Changes In Female Adults With High Adiposity ( Co-Researcher)
- 2019 - 2023, Fundamental Research Grant Scheme (FRGS)Investigation On The Role Of Oxidative Imbalance And Molecular Alterations In The Transformation Of Benign To Malignant Thyroid Tumours ( Co-Researcher)
- 2019 - 2023, Fundamental Research Grant Scheme (FRGS)A Comprehensive Investigation Of The Rhythmic Biochemical, Metabolic And Proteomics Changes In Different Phenotypes Of Pancreatic Ductal Adenocarcinoma ( Principal Investigator(PI))
- 2019 - 2022, Fundamental Research Grant Scheme (FRGS)Evaluation Of Circadian Timekeeping, And Protective Effects Of Melatonin On 24-hour Proteome Profile And Core Clock Genes In Tumor-induced Drosophila Melanogaster ( Co-Researcher)
- 2019 - 2022, RU Geran - Fakulti ProgramA Targeted Proteomics Mrm-ms Study On Potential Prostate Cancer Biomarkers In Human Serum And Urine Development Of Elisa For An Improved Method Of Diagnosis ( Principal Investigator(PI))
- 2017 - 2021, Fundamental Research Grant Scheme (FRGS)Study Of Tear Proteomic Patterns In Keratoconus In The Malaysian Population ( Co-Researcher)
- 2017 - 2019, UM Grant - Frontier Research GrantProfiling Of Human Hair Shaft Glycoproteins Using Lectin-based Proetomics For Improved Identity Discrimintion ( Principal Investigator(PI))
- 2017 - 2019, Research Officer Grant Scheme (ROGS)Development Of Tests To Distinguish Benign Prostatic Hyperplasia From Prostate Cancer ( Principal Investigator(PI))
- 2013 - 2016, Geran Penyelidikan Universiti Malaya (UMRG Programme) - HTM (Wellness)Functional Proteomic Analysis Of Circadian Clock Gene Products In Drosophila And Mammalian Systems ( Co-Researcher)
- 2017 - 2021, Fundamental Research Grant Scheme (FRGS)Tear proteomics and pathophysiology of keratoconus ( Consultant)
- 2010 - 2013, Geran Penyelidikan Universiti Malaya (UMRG)APPLICATION OF LECTIN IN THE STUDY OF PROSTATE CANCER ( Principal Investigator(PI))
- 2006 - 2008, Postgraduate Research Grant(PPP)PPP Grant: Angiotensin-I converting enzyme (ACE) gene polymorphism among Malaysian population and their relationship to diabetic nephropathy. ( Principal Investigator(PI))
International
- 2021 - 2023, International FundingLectin & Biomarker For Diseases ( Principal Investigator(PI))
- 2023 - 2023, International FundingCharacterisation Of Quorum Sensing Inhibitor-producing Bacteria From Marine Samples To Control Escherichia Coli ( Principal Investigator(PI))
- 2018 - 2019, International FundingAcademic Visit To Iitb ( Principal Investigator(PI))
PAPER PRESENTED
INVITED SEMINAR
- Proteomics & MS: Basic Concept & Application, Research Seminar Series: Protein Profiling, Department of Molecular Medicine & Department of Pharmacology, Faculty of Medicine, University of Malaya (University) (12 Nov 2018 - 12 Nov 2018)
INVITED SPEAKER
- Mass spectrometery and Proteomics, Pre-conference Seminar Series at 33rd Malaysian Society of Pharmacology and Physiology (MSPP) Scientific Meeting 2019, MSPP 2019 (University) (12 Jul 2019 - 12 Jul 2019)
- Identification of potential serum and urine biomarkers for patients with prostate cancer using lectin-based proteomic analyses., Collaborative Research Visit Seminar, Department of Biochemistry and Biotechnology, Faculty of Science, Annamalai University (International) (02 Mar 2015 - 02 Mar 2015)
- Proteomics Facility, Biotech Open Day 2013, Medical Biotechnology Laboratory, Faculty of Medicine, University of Malaya (University) (13 Nov 2013 - 13 Nov 2013)
- Our Facilities & Services, UMCPR Research Day Cum Proteomics Workshop, UMCPR (University) (21 Jun 2012 - 21 Jun 2012)
- Prostate cancer proteomics, Malaysian Urology Research Seminar, Malaysian Urological Association (National) (23 Feb 2011 - 23 Feb 2011)
ORAL PRESENTER
- SERUM AND URINE INTER-ALPHA-TRYPSIN INHIBITOR PEPTIDES: A POTENTIAL BIOMARKER FOR DIFFERENTIATING CANCER FROM BENIGN PROSTATE, International Meeting & 42nd Annual Conference of the Malaysian Society for Biochemistry & Molecular Biology in conjunction with the 3rd Joint International Symposium of Animal Cell Technology, Malaysian Society for Biochemistry & Molecular Biology (International) (16 Aug 2017 - 17 Aug 2017)
- Potential use of reciprocal levels of serum and urinary peptides for discriminating prostate cancer from benign prostatic hyperplasia., 7th International Conference on Proteomics & Bioinformatics, Conference Series LLC (International) (24 Oct 2016 - 26 Oct 2016)
- Proteomics Analysis of Sera and Urine from Patients with Prostate Cancer, Proteomics Symposium 2013, UMCPR (University) (23 Jan 2013 - 23 Jan 2013)
- Prostate cancer & Proteomics, Prostate & Ketamine Research Seminar 2012, Department of Surgery, Faculty of Medicine, UM (Others) (13 Feb 2012 - 13 Feb 2012)
POSTER PRESENTER
- In Vivo BIOCHEMICAL ANALYSIS OF ANTIOXIDANT AND ANTI-DIABETIC PROPERTIES OF Tamarindus Indica SEED EXTRACT, 47th Annual Conference of The Malaysian Society for Biochemistry and Molecular Biology (IM-MSBMB47), Malaysian Society for Biochemistry & Molecular Biology (MSBMB) (International) (23 Aug 2023 - 24 Aug 2023)
- Proteomic Analysis Reveals Protective Role of Melatonin in Tumour-Prone Drosophila melanogaster lethal giant larvae Mutants, 4th International Conference on Molecular Biology and Biotechnology 2021, Malaysian Society of Molecular Biology and Biotechnology (MSMBB) (International) (01 Jun 2021 - 03 Jun 2021)
- Comparative proteomics profiling of serum of women with BIRADS scores of 1 to 5 using gel-based approaches., 4th International Conference on Molecular Biology and Biotechnology 2021, Malaysian Society of Molecular Biology and Biotechnology (MSMBB) (International) (01 Jun 2021 - 03 Jun 2021)
- Differential Lipocalin-1 Levels in Keratoconus in a Malaysian Cohort, 4th International Conference on Molecular Biology and Biotechnology 2021 (ICMBB2021), Malaysian Society of Molecular Biology and Biotechnology (MSMBB) (International) (01 Jun 2021 - 03 Jun 2021)
- IDENTIFICATION OF POTENTIAL HUMAN HAIR SHAFT PEPTIDE BIOMARKERS FOR DISTINGUISHING GENDER AND ETHNICITY , 24th Biological Sciences Graduate Congress, BSGC Committee (National) (19 Dec 2019 - 20 Dec 2019)
- CAN KERATIN SIGNATURES OF THE HUMAN HAIR SHAFT BE POTENTIALLY USED TO DISTINGUISH GENDER AND ETHNICITY?, 27th FAOBMB Conference & 44th Annual Conference of the MSBMB, FAOBMBKL2019 (International) (19 Aug 2019 - 22 Aug 2019)
- Hesperidin modulates the circadian proteomic profiling in Drosophila melanogaster under oxidative stress., National Conference on Drug Discovery & Translational Medicine, Department of Biochemistry & Biotechnology, Annamalai University (International) (14 Mar 2019 - 16 Mar 2019)
- TEMPORAL REGULATION OF PROTEIN EXPRESSION IN DROSOPHILA MELANOGASTER, 41st Annual Conference of the Malaysian Society for Biochemistry and Molecular Biology, Malaysian Society for Biochemistry and Molecular Biology (International) (17 Aug 2016 - 18 Aug 2016)
- University of Malaya Center for Proteomics Research (UMCPR), UM RESEARCH CARNIVAL 2015, Frontier Science Research Cluster (University) (07 Oct 2015 - 08 Oct 2015)
- Lectin-based Proteomics, UM Researchers Conference 2012, IPPP, UM (University) (23 Apr 2012 - 24 Apr 2012)
- Lectin-based glycoproteomic profiling of serum samples from patients with prostate cancer., 31st Congress of the Societe Internationale d'Urologie (SIU), 31st Congress of the Societe Internationale d'Urologie (SIU) (International) (16 Oct 2011 - 20 Oct 2011)
- Lectin-based glycoproteomic profiling of serum samples from patients with prostate cancer., 19th Malaysian Urological Conference, Malaysian Urological Association (National) (26 Nov 2010 - 28 Nov 2010)
OTHERS
- To develop strategic plans for Research Communication Unit, Research Away Day 2020, Deputy Dean (Research) Office (University) (19 Dec 2020 - 19 Dec 2020)
- The use of urinary inter-alpha trypsin inhibitor peptides as biomarkers to discriminate benign prostatic hyperplasia from prostate cancer., 2nd International Caparica Conference on Urine Omics & 2nd International Caparica Conference In Translational Nephrology, ProteoMass Scientific Society BIOSCOPE Research Team Caparica Cientifica (International) (28 Sep 2015 - 30 Sep 2015)
- UM Researchers' Conference 2013, UM Researchers' Conference 2013, IPPP, UM (University) (19 Nov 2013 - 20 Nov 2013)
ACADEMIC/PROF. SERVICES
Evaluation
- (2023) Phd Thesis_17004604, University, (Internal Examiner)
- (2023) Panel Penemuduga Bagi Kemasukan Ke Program Pengajian Peringkat Ijazah Sarjana Muda Ambilan Sesi Akademik 2023/2024, University, (Internal Evaluator)
- (2023) Manuscript # Tcrt-22-1472.R1, International, (Reviewer)
- (2023) Phd Cd: Comparative Toxicity, Neutralization and Proteomics of Venoms from Selected Medically Important Trimeresurus Pit Viper Species in Asia, University, (Internal Examiner)
- (2023) Pemeriksa Luar Bagi Pemeriksaan Tesis Kursus Tfm511-Projek Penyelidkan (Project Research) Untuk Program Sarjana Perubatan Molekul (Mod Campuran), National, (External Examiner)
- (2022) Reviewer - Manuscript Id Tcrt-22-1472 for Technology in Cancer Research & Treatment, International, (Reviewer)
- (2022) 3 Minute Thesis (3mt) Bagi Kursus Metodologi Penyelidikan, Fakulti Perubatan, University, (Internal Evaluator)
- (2022) Confirmation Seminar for a Fast Track Phd Candidate_ Dept of Surgery, University, (Internal Evaluator)
- (2022) Frontiers in Veterinary Science_1016312, International, (Reviewer)
- (2022) Panel Reviewer for Umsc Ca.R.E Fund (Research Grant) Cycle 1/2022, University, (Reviewer)
- (2022) Reviewer for Article in Jpr, International, (Reviewer)
- (2022) Phd Candidate_(17007142/2), University, (Internal Examiner)
- (2022) Evaluator_chairperson - Mmedsc Candidate (17219578), University, (Internal Evaluator)
- (2022) Reviewer for Article in Journal - Manuscript Id 822310, International, (Reviewer)
- (2021) Panel Penemuduga Kemasukkan Program Pengajian Peringkat Ijazah Sarjana Muda Ambilan Sesi 2021/2022, University, (Internal Assessor)
- (2021) Panel Reviewer for The Fundamental Research Grant Scheme (Frgs) 2021 Application, University, (Reviewer)
- (2021) An Investigation Into The Effects of Clinical Hif Prolyl-Hydroxylase Inhibitors On Human Lung Cancer Progression, University, (Internal Assessor)
- (2021) Galectin-3 Participates in Epithelial-Mesenchymal Transition in Thyroid Papillary Carcinoma, International, (Reviewer)
- (2021) Evaluator For PhD Proposal Defense - Jan 2021, (Evaluator For PhD Candidature Defense - Jan 2021)
- (2021) Panel penilai tetap: Evaluator for MMedSc proposal defense - Jan 2021 (n=2), (Evaluator for MMedSc proposal defense - Jan 2021)
- (2020) Research project TFM515 - Informm, USM , (External Examiner)
- (2020) Assessor for PhD proposal defense_Chee Cheok Wui , (Examiner)
- (2020) Evaluator for MMedSc project proposal defence - Aug & Sep 2020 (n=3) , (Examiner)
- (2020) Interviewer: Bachelor of Medicine and Bachelor of Surgery Admission Interview May 2020, (Interviewer)
- (2020) PhD Proposal defence seminar - July & Sep 2020 (n=2) , (Examiner)
- (2020) Evaluator for MMedSc project application (JKITJ) - June Xin , (Examiner)
- (2020) Examiner for Final Year Project: MIC160033, (Examiner)
- (2020) Examiner for Final Year Project: MIC160036, (Examiner)
- (2020) Advisor for MOE Fundamental Research Grant Scheme 2020/cycle 1 , (Advisor)
- (2020) Professional Examination 3.2, MBBS Session 2018/2020, Mar 2020, (Invigilator )
- (2019) Evaluator for Candidature Defence Seminar MMedSc Degree: Hair Protein Proteomics, (Evaluator)
- (2019) MMedSc Thesis: Examination of Circulating Proteins in Plasma of HIV- Infected Patients with Chronic Kidney Disease , (Internal Examiner)
- (2019) Evaluator for Candidature Defence Seminar MMedSc Degree: Obesity & Redox status, (Evaluator)
- (2019) Interviewer: Bachelor of Medicine and Bachelor of Surgery Admission Interview (Multiple Mini Interview) , (Interviewer)
- (2019) Pengawas peperiksaan kursus universiti (TITAS) sem II sesi 2018/2019 , (Invigilator)
- (2019) Examiner for Candidature Defence Seminar MMedSc Degree: Chronic kidney disease & proteomics , (Examiner)
- (2019) Final Year Project Examiner: Experimental study of plasmodium knowlesi normocyte binding protein XA region II for erythrocyte binding: molecular cloning, protein expression and binding assay , (Final year project examiner)
- (2019) Final Year Project Examiner: Profiling of unknown novel proteins in Tropidolaemus wagleri venow , (Final year project examiner)
- (2019) Peperiksaan professional ijazah sarjana muda pembedahan pergigian sesi 2018/2019, (Internal Examiner)
- (2019) Doctoral (PhD) Thesis: PROTEOMICS AND TOXINOLOGICAL STUDY OF THE VENOMS FROM AFRO-ASIAN COBRAS (NAJA SPP) , (Internal Examiner)
- (2019) Examiner: Proposal Defence Seminar for MMedSc Degree : Zika Virus , (Examiner Panel & HOD Rep)
- (2018) Reviewing for Electrophoresis , (Reviewer)
- (2018) Panel of examiner for Proposal Defence Seminar - MMedSc Degree (supervisor) , (Examiner for Proposal Defence Seminar)
- (2018) ELECTROPHORESIS , (Reviewer)
- (2017) Cancer Studies: Rivera Publications, (Reviewer)
- (2017) Journal of Proteome Research - ACS Publications, (Reviewer)
- (2017) Applied Biochemistry and Biotechnology - Springer, (Reviewer)
- (2016) Open Journal of Proteomics - Peertechz, (Reviewer)
- (2016) SM Journal of Bioinformatics and Proteomics (SMJBP). , (Reviewer)
- (2016) Future Science OA - Future Science Group , (Reviewer)
- (2016) COMPETENCY ASSESSMENT PROGRAMME FOR STAFF FOR ACCREDITATION OF MS ISO/IEC 17025:2005, (Reviewer)
- (2016) Work Instruction for SAMPLE RECEIVING FOR MALDI ToF/ToF ANALYSIS (MBL/WI/015), (Reviewer)
- (2015) COMPETENCY ASSESSMENT PROGRAMME FOR STAFF FOR ACCREDITATION OF MS ISO/IEC 17025:2005, (Reviewer)
- (2014) Work Instruction for MICROCENTRIFUGE(MBL/WI/002), (Reviewer)
- (2014) Work Instruction for FREEZER -20 C (MBL/WI/001), (Reviewer)
- (2014) Work Instruction for SPEED VACUUM CONCENTRATOR II (SAVANT)(MBL/WI/007), (Reviewer)
- (2014) Work Instruction for MINI SHAKER (MBL/WI/004), (Reviewer)
- (2014) Work Instruction for MALDI ToF/ToF 5800 (MBL/WI/0017), (Reviewer)
- (2014) Work Instruction for CHILLER (MBL/WI/0012), (Reviewer)
- (2014) Work Instruction for THERMOMIXER (MBL/WI/011), (Reviewer)
- (2014) Work Instruction for WEIGHING SCALE (MBL/WI/0010), (Reviewer)
- (2014) Work Instruction for WATER BATH (MBL/WI/009), (Reviewer)
- (2014) Work Instruction for SPEED VACUUM CONCENTRATOR I (SCANVAC)(MBL/WI/006), (Reviewer)
- (2014) TEST METHOD FOR PROTEIN IDENTIFICATION IN BIOLOGICAL SAMPLES (UM/MBL/TM-1 - Revision 3), (Reviewer)
- (2014) Work Instruction for PROTEIN PILOT SOFTWARE (MBL/WI/0018), (Reviewer)
- (2014) Work Instruction for OPTI-TOF 384 WELL MALDI PLATE INSERT WASH (MBL/WI/0016), (Reviewer)
- (2014) Work Instruction for IMAGE SCANNER (MBL/WI/0014), (Reviewer)
- (2014) Work Instruction for VORTEX MIXER (MBL/WI/008), (Reviewer)
- (2014) COMPETENCY ASSESSMENT PROGRAMME FOR STAFF FOR ACCREDITATION OF MS ISO/IEC 17025:2005, (Reviewer)
- (2014) Work Instruction for PIPETTE (MBL/WI/005), (Reviewer)
- (2014) Work Instruction for RESULTS SAVING (MBL/WI/0019), (Reviewer)
- (2014) Work Instruction for FREEZER -80 C (MBL/WI/0013), (Reviewer)
- (2014) Work Instruction for MILLIPORE MILLI Q ACAEMIC WATER PURIFICATION SYSTEM (MBL/WI/003), (Reviewer)
Contribution to external organisation
- (2024) International Collaboration, International, (Resource Person)
- (2023) Technical Manager & Approved Signatory: Ms Iso/Iec 17025:2005, University, (Resource Person)
- (2022) Judge and Advisor in The Solve for Tomorrow Competition by Samsung, National, (Resource Person)
- (2021) Reviewer - original research article for Technology in Cancer Research & Treatment, Technology in Cancer Research & Treatment, International
- (2021) Tips For Effective Course Design & Delivery Seminar, Department of Molecular Medicine, FoM, UM
- (2020) MoU, Annamalai University , International
- (2020) Industrial Training , Universiti Sains Malaysia, National
- (2020) Reviewer - original research article for Lipid in Health & Disease, Lipid in health & disese, International
- (2020) Reviewer - original research article for Technology in Cancer Research & Treatment, Technology in Cancer Research & Treatment, International
- (2020) Reviewer - original research article for Cancer Medicine, Wiley , International
- (2020) Reviewer for Journal of Functional Foods, Elsevier, International
- (2020) Reviewer - original research article for Cancer Medicine, WIley, International
- (2020) Committee Member, Evaluation of Quotation, MBL, FoM, UM, Sept 2020. , MBL, FoM, UM
- (2020) Multiplex Immunoassay and Multiplex Gene Expression seminar, Department of Molecular Medicine, FoM, UM with iDNA
- (2020) Jawatankuasa Penilaian Spesifikasi & Teknikal_Mircoplate Reader, Department of Molecular Medicine
- (2020) Competency Assessment for continuing accreditation of MS ISO/IEC 17025:2005 at MBL, FoM, MBL, FoM, UM
- (2020) Bridging Translational Cancer Research Forum, UMCRi, FoM, Mar 2020., UMCRi, UMMC
- (2019) Reviewer, Journal Technology in Cancer Research & Treatment (TCRT)., International
- (2019) Reviewer , Pharmacognosy Magazine, Medknow Publications , International
- (2019) Reviewer, Journal Electrophoresis, International
- (2019) The drosophila: A versatile model for biomedical research Workshop, Central Research Laboratories & University of Malaya Centre for Proteomics Research
- (2019) Seminar: Chromosal instability in gastric cancer, Department of Molecular Medicine/FoM with Eramus International Credit Mobility Programme
- (2019) Evaluation of Quotation - Preventive Maintenance MALDI, CRL, FoM UM
- (2019) Competency Assessment for continuing accreditation of MS ISO/IEC 17025:2005 at MBL, FoM, MBL, FoM
- (2019) Facilitator for Medical History Taking, Merdu FoM
- (2019) Seminar: The beauty of molecules, Department of Molecular Medicine
- (2018) Journal Article Writing Workshop: Preparation for Publication, JMRG & IPPP
- (2016) AJK Penilaian Sebutharga - 1 unit of Electronic digital pipette accuracy measuring tester , FOM Calibration Laboratory, Faculty of Medicine, University of Malaya
- (2016) Organise & Supervise - COMPETENCY ASSESSMENT PROGRAMME FOR STAFF FOR ACCREDITATION OF MS ISO/IEC 17025:2005, Medical Biotechnology Laboratory & UMCPR, Faculty of Medicine, UM
- (2016) AJK Penilaian Sebutharga - Analytical Balance (3 unit), Makmal Bioteknologi Perubatan, Fakulti Perubatan, Universiti Malaya
- (2016) AJK Penilaian Sebutharga: Preventive maintenance and repairing of gilson 215 liquid handler system., Makmal Bioteknologi Perubatan, Fakulti Perubatan, Universiti Malaya
- (2015) AJK Penilaian Harga 'Non comprehensive service contract for BDFACSCanto II', Medical Biotechnology Laboratory, Faculty of Medicine, UM
- (2015) AJK Penilaian Harga '-80oC Freeze'., Medical Biotechnology Laboratory, Faculty of Medicine, UM
- (2015) Organise & Supervise - COMPETENCY ASSESSMENT PROGRAMME FOR STAFF FOR ACCREDITATION OF MS ISO/IEC 17025:2005, Medical Biotechnology Laboratory & UMCPR, Faculty of Medicine, UM
- (2014) AJK Penilaian Harga ' Electric Cell Substrate Impedance Sensing System', Makmal Bioteknologi Perubatan, Fakulti Perubatan, Universiti Malaya
- (2014) Organise & Supervise - COMPETENCY ASSESSMENT PROGRAMME FOR STAFF FOR ACCREDITATION OF MS ISO/IEC 17025:2005, Medical Biotechnology Laboratory & UMCPR, Faculty of Medicine, UM
- (2013) AJK Penilaian Sebutharga 'Repairing of Biacore 3000 System', Makmal Bioteknologi Perubatan, Fakulti Perubatan, Universiti Malaya
- (2013) AJK rundingan harga penggantian laser baru bagi peralatan 'SELDI ToF' , Makmal Bioteknologi Perubatan, Fakulti Perubatan, Universiti Malaya
- (2013) AJK penilaian spesifikasi & teknikal'LC-MS/MS', Makmal Bioteknologi Perubatan, Fakulti Perubatan, Universiti Malaya
- (2013) AJK rundingan harga 'Field Emission Scanning Electron Microscope', Makmal Bioteknologi Perubatan, Fakulti Perubatan, Universiti Malaya
- (2013) AJK rundingan harga 'repairing of Biacore', Makmal Bioteknologi Perubatan, Fakulti Perubatan, Universiti Malaya
- (2013) AJK rundingan harga untuk 'cryostat', Makmal Bioteknologi Perubatan, Fakulti Perubatan, Universiti Malaya
- (2013) AJK rundingan harga 'monochrome microplate reader', Makmal Bioteknologi Perubatan, Fakulti Perubatan, Universiti Malaya
- (2013) AJK penilaian Sebutharga 'Consumables', Jabatan Perubatan Molekul, Fakulti Perubatan, Universiti Malaya
- (2013) AJK Penilaian Sebutharga 'Non Comprehensive Service Contract for BD FACSCanto II', Makmal Bioteknologi Perubatan, Fakulti Perubatan, Universiti Malaya
- (2012) AJK Penilaian Spesifikasi dan Teknikal 'Protein Array', Jabatan Perubatan Molekul, Fakulti Perubatan, Universiti Malaya
- (2012) AJK Penilaian Rundingan Harga 'Protein Array', Jabatan Perubatan Molekul, Fakulti Perubatan, Universiti Malaya
- (2012) AJK Penilaian Spesifikasi dan Teknikal 'Tissue Imaging Software', Makmal Bioteknologi Perubatan, Fakulti Perubatan, Universiti Malaya
- (2012) AJK Penilaian Harga 'Monochrome Microplate Reader', Makmal Bioteknologi Perubatan, Fakulti Perubatan, Universiti Malaya
- (2011) AJK Penilaian Harga 'RT-PCR', Medical Biotechnology Laboratory, Faculty of Medicine, University of Malaya
- (2011) AJK Penilaian Harga 'Cell Sorter', Medical Biotechnology Laboratory, Faculty of Medicine, University of Malaya
- (2011) AJK Penilaian Harga '2D Electrophoresis System & Image Analysis Software', Medical Biotechnology Laboratory, Faculty of Medicine, University of Malaya
Contribution to event
- (2023) Participant: International Cancer Proteogenomics Symposium 2023 Tokyo, International, (Participant)
- (2022) AJK - Research Carnival Fom, University, (Event Organiser)
- (2022) Participant - Foundations of Assessment for Health Professionals Workshop, University, (Participant)
- (2022) Participant_webinar_advancing Your Life Science Research Applications With Ella and Luminex Immunoassay, University, (Participant)
- (2022) Protein & Glycan Sample Preparation for Mass Spectrometry, National, (Participant)
- (2022) Science Communication Series III: How to Engage and Boost Participation Among Your Audience?, University, (Event Coordinator)
- (2022) Participant - Science Communication Series III Webinar: How to Engage and Boost Participation Among Your Audience?, University, (Participant)
- (2022) Participant_aua Scholars International Roundtable 2022, International, (Participant)
- (2021) Guest Speaker, University, (Panelist/Moderator)
- (2021) Organising Chairperson: Tips for Effective Course Design & Delivery Workshop, University, (Event Organiser)
Mentoring
- (2023) Lead Mentor - Apru Sdg Education for Global Citizenship Program 2022-2023 Themed, Shaping The Future of Health and Wellbeing, International, (Mentor)
- (2023) Penasihat Akademik Pelajar MBBS Tahap 1, University, (Mentor)
SUPERVISION
Postgraduate Student
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(2024) ELUCIDATING THE PREDICTORS FOR EARLY DETECTION OF DIASTOLIC DYSFUNCTION IN WOMEN WITH OBESITY, DYG MASTURA BINTI ADENAN
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(2024) MASS SPECTROMETRIC AND IMMUNOHISTOCHEMISTRY PROFILING OF STAGE-SPECIFIC N- AND O- GLYCANS FOR IDENTIFICATION OF A POTENTIAL PROSTATE CANCER BIOMARKER, IVY CHEW YEE YEN
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(2024) Biochemical and Molecular Analysis of Antioxidant and Anti-diabetic Effects of Tamarindus indica Seed Extract in a Diabetic Rat Model, INTAN NURASHIKIN BINTI MOHD ADNAN
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(2024) Study of Tear Proteome and Cellular Pathophysiology of Keratoconus, NG JUN BIN
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(2023) Proteomics profiling of Escherichia coli treated with pyridoxine and cell-free supernatant extracts of Staphylococcus warneri, a quorum sensing inhibitor-producing bacterium, Nattarika Chaichana (University is Prince of Songkla University (Psu))
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(2020) Study of Tear Proteome and Cellular Pathophysiology of Keratoconus, NG JUN BIN
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(2019) Study of Tear Proteome and Cellular Pathophysiology of Keratoconus, NG JUN BIN
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(2024) Development of Quantitative Multiplexed MRM-MS Method for Prostate Cancer Urinary Protein Biomarkers Detection, DIVYA DHARSHINI
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(2024) Investigation of Rhythmic Changes in the Redox Homeostasis and Proteome of Different Subtypes of Pancreatic Ductal Adenocarcinoma, CHRISTINA JANE A/P VELLAN
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(2022) The Effects of Melatonin on the Regulation of Redox Homeostasis and Circadian Proteome Profiles in Tumour-Induced Drosophila Melanogaster Model, WONG KAR CHENG
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(2021) CORRELATION OF REDOX STATUS WITH CARDIOPULMONARY RESPONSE IN OBESE WOMEN AND IDENTIFICATION OF POTENTIAL BIOMARKERS FOR EARLY DETECTION OF OXIDATIVE STRESS., DYG MASTURA BINTI ADENAN
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(2020) EVALUATION OF CIRCADIAN TIMEKEEPING AND PROTECTIVE EFFECTS OF MELATONIN ON PROTEOME PROFILE IN TUMOUR-INDUCED DROSOPHILA MELANOGASTER
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(2020) Correlation between antioxidant activities and biomarkers of oxidative stress with cardiopulmonary responses in female adults with varying body mass index., DYG MASTURA BINTI ADENAN
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(2020) A TARGETED MRM-MS, LECTIN- AND ANTIBODY-BASED PROTEOMICS STUDY ON POTENTIAL PROSTATE CANCER BIOMARKERS IN HUMAN SERUM AND URINE.
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(2020) USE OF HUMAN HAIR SHAFT KERATIN FOR THE IDENTIFICATION OF GENDER AND ETHNICITY, NURDIENA BINTI MOHAMED NASIR
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(2019) POTENTIAL USE OF HUMAN HAIR SHAFT PROTEINS FOR IDENTIFICATION OF GENDER, AGE AND ETHNICITY, NURDIENA BINTI MOHAMED NASIR
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(2019) Correlation between antioxidant activities and biomarkers of oxidative stress with cardiopulmonary responses in female adults with varying body mass index., DYG MASTURA BINTI ADENAN
Under Graduate Students
- (2022) Validation of differently expressed glycosylated proteoglycan 4 in the serum of patients with breast cancer stage 0 -2
- (2022) Comparative Profiling of Serum Glycoproteome of Women With Breast Imaging Reporting and Data System Scores of 1 To 5 using Lectin and Mass Spectrometric Analysis
- (2021) Validation of differently expressed glycosylated proteoglycan 4 in the serum of patients with breast cancer stage 0 -2
- (2021) Comparative Profiling of Serum Glycoproteome of Women With Breast Imaging Reporting and Data System Scores of 1 To 5 using Lectin and Mass Spectrometric Analysis
- (2019) Internship - NurShazleen Rohaizad (M0100104)
- (2019) Differential Proteomics Profiling of Serum of Women with Breast Imaging-Reporting and Data System (BI-RADS) Scores 1-5 - FYP
- (2017) Identification of potential urine biomarkers for patients with precocious puberty using proteomic analyses. (Elective Host)
TEACHING
Bachelor
- (2023) NA - Dia Sem I 2023_2024
- (2023) NA - Dia Sem I & Ii 2022_2023
- (2023) NA - Gdm0006 Sem Ii 2022/2023
- (2023) NA - Gim 2001 Sem Ii 2022/2023
- (2023) NA - Mix 3001 Sem Ii 2022/2023
- (2023) NA - Ummp Stage 1 & 2 2022 2023
- (2023) NA - Ummp Stage 1 & 2 2023 2024
- (2022) NA - Dia 1003 Sem I 2022/2023
- (2022) NA - Dia 1003 Sem I & Sem Ii - 2021/2022
- (2022) NA - Gdm 0006 - Sem Ii 2021/2022
- (2022) NA - Gim 2001 - Sem Ii 2021/2022
- (2022) NA - Mix 3001 - Sem Ii 2021/2022
- (2022) NA - Ummp Stage 1 & 2 2022/2023
- (2022) NA - Ummp - Stage 1 & Stage 2 2021/2022 - Sem I & Ii
- (2019) DIA1003 - Biochemistry
- (2019) MIX3001 - Techniques in Molecular Medicine
- (2019) MIX3001 - Techniques in Molecular Medicine
PATENT/IPR
- Method of Diagnosis and/or Discrimination of Prostate CancerPatent (International)
- Use of indices relating to levels of serum and urinary fragment peptides of inter-alpha trypsin inhibitor light and heavy chain h4 for diagnosis and/ or discrimination of prostate cancer, 2014Patent (National)
SOCIAL RESPONSIBILITY ACTIVITIES
- Judge for The 1st Phase of Samsung Solve for Tomorrow (Ssft) 2023 Competition I Have Volunteered for Serving as a Judge in The Ssft Competition Under The Sub-Theme, &Quot;Health and Well Being&Quot;. I Am Required to Evaluate a Total of 2 Abstracts That Have Been Submitted for This Competition. The Competition is About How Schoolgoers Utilise Stem to Solve a Problem Faced by The Community., (22 Sep 2023 - 02 Oct 2023) (National)
- Served as An Advisor for The Program Bengkel Pemantapan Staf 2023, Jabatan Perubatan Molekul, Fakulti Perubatan. The Program Was Intended for All Staff At The Department of Molecular Medicine, UM. The Program Was Aimed to Enhance Teamwork, Foster Excellence, and Support Holistic Growth for Both Individuals and The Department., (13 Feb 2023 - 06 Jul 2023) (University)
- Lead Mentor I Have Volunteered and Henceforth, Been Appointed as a Lead Mentor for The Apru Sdg Education for Global Citizenship Themed, “Shaping The Future of Health & Wellbeing” by Chulalongkorn University, Thailand. The Apru Sdg4gc is An Intercultural, Transdisciplinary, and Interactive Program That Fosters Global Citizenship Among Students from 60 Universities in 19 Economies Across The Pacific Rim. Co-Designed by Six Core-Partner Universities in Collaboration With The United Nations (Un), The Program Builds Knowledge of Global Issues and Global Literacy Among Students. as a Lead Mentor of This Program, I Am Required to 1.1. to Propose a Contributing Sub-Theme to The Mentorship Program Under “Health and Wellbeing” 1.2. to Facilitate Students’ Teamwork in Developing Social Innovation Prototype 1.3. to Provide Academic Guidance Related to The Program Theme 1.4. to Provide Insights and Experiences and Guide Students On The Co-Creation of Knowledge With Practitioners and Other Stakeholders of Society 1.5. to Participate in The Two (2) Train-The-Trainer Sessions to Be Conducted by Social Innovation Program Designers 1.6. to Assess The Mentees’ Performance Based On Which The Program Steering Committee Will Issue a Certificate of Program Completion to The Students, (01 Nov 2022 - 01 Jun 2023) (International)
- Judge for 1st Phase of Samsung Solve for Tomorrow 2022 Competition I Have Volunteered for Serving as a Judge in The Solve for Tomorrow Competition Under The Sub-Theme, "Health and Well Being". I Am Required to Evaluate a Total of 3 Abstracts That Have Been Submitted for This Competition. The Competition is About How Schoolgoers Utilize Stem Thinking to Impact Their Community., (30 Sep 2022 - 03 Oct 2022) (National)
- Makna Volunteer, (08 Aug 2016 - 31 Dec 2018)
COURSE ATTENDED
Internal / External Course
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SHORT TERM ACADEMIC VISIT TO IBMBB UNIVERSITY OF COLOMBO, (17 Jan 2022 - 28 Jan 2022)
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KURSUS PENGENDALIAN BAHAN KIMIA DAN PENGURUSAN RISIKO BAGI STAF MAKMAL AKREDITASI ISO 17025 UNIVERSI, Pullman Bangsar, Kuala Lumpur (13 Dec 2022 - 13 Dec 2022)
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CREATING RUBRICS: THE HOW AND WHY?, Universiti Malaya (04 Oct 2022 - 04 Oct 2022)
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HOW TO CRAFT A GREAT CURRICULUM VITAE (CV)?, ?Microsoft Teams (Jabatan Perubatan Molekul | Department of Molecular Medicine Fakulti Perubatan | Faculty of Medicine) (08 Apr 2023 - 08 Apr 2023)
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SUPERCHARGE YOUR CLASS WITH CHATGPT, Dalam Talian (19 May 2023 - 19 May 2023)
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BENGKEL PEMANTAPAN STAF JABATAN PERUBATAN MOLEKUL, Tadom Hill Resort, Banting, Selangor (06 Jul 2023 - 06 Jul 2023)
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EMERALD RESEARCH AND SUPERVISION 2023, Universiti Malaya (15 Aug 2023 - 17 Aug 2023)
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EFFECTIVE COACHING, COUNSELLING AND MENTORING TO DEVELOP OTHERS, Aras 4 Bilik Senat Bangunan Canseleri (31 May 2023 - 31 May 2023)