Curriculum Vitae

DR. CHAI HWA CHIA

Senior Lecturer
  • Department of Biomedical Science
    Faculty of Medicine
  • hccha18
  • 03-79677522

AREAS OF EXPERTISE

  • PARASITOLOGY
    Diagnostics of Plasmodium spp.
  • PROTEOMICS
    electrophoresis, 2D-electrophoresis, LCMS
  • MOLECULAR GENETICS
    PCR, real-time PCR
  • IMMUNOGENETICS
    Systemic lupus erythematosus

ACADEMIC QUALIFICATION

  • PhD (Medical Science) Monash University, (Medical Science)
    Monash University, (Malaysia Campus)
  • Master (Medical Science) University of Malaya, (Medical Science)
    Universiti Malaya (UM)
  • Bachelor (Biomedical Science) University of Malaya, (Biomedical Science)
    Universiti Malaya (UM)

ADMINISTRATIVE DUTIES

  • Penyelaras Penyelidikan bagi Pengumpulan Data KPI dan MYRA (Jabatan Sains Bioperubatan)
    01 Jan 2018 - 31 Dec 2020 (Department of Biomedical Science, Faculty of Medicine)
  • Jawatankuasa Peperiksaan (Jabatan Sains Bioperubatan)
    13 Dec 2018 - 31 Dec 2020 (Department of Biomedical Science, Faculty of Medicine)
  • Curriculum Review Committee (Jabatan Sains Bioperubatan)
    01 Jan 2018 - 31 Dec 2020 (Department of Biomedical Science, Faculty of Medicine)

MEMBERSHIPS

  • MALAYSIAN SOCIETY OF PARASITOLOGY & TROPICAL MEDICINE (MSPTM), MEMBER
    2023 to 2024 (National)
  • BIOMEDKL, MEMBER
    Since 2018 (National)
  • MALAYSIAN SOCIETY OF PARASITOLOGY AND TROPICAL MEDICINE (MSPTM), MEMBER
    2021 to 2022 (National)

PUBLICATIONS

Article in Journal
WoS
  1. Chai, Hwa Chia; Chua, Kek Heng (2021). The Potential Use of Volatile Biomarkers for Malaria Diagnosis, DIAGNOSTICS. 11(12). doi:10.3390/diagnostics11122244
  2. Liew, S. M., Puthucheary, S. D., Rajasekaram, G., Chai, H. C., & Chua, K. H. (2021). Proteomic profiling of clinical and environmental strains of Pseudomonas aeruginosa. Molecular Biology Reports, 48(3), 2325-2333. doi: 10.1007/s11033-021-06262-8
  3. Mahendran, R., Lim, S. K., Ong, K. C., Chua, K. H., & Chai, H. C. (2021). Natural-derived compounds and their mechanisms in potential autosomal dominant polycystic kidney disease (ADPKD) treatment. Clinical and Experimental Nephrology, 25(11), 1163-1172. doi: 10.1007/s10157-021-02111-x
  4. Chong, E. T. J., Neoh, J. W. F., Lau, T. Y., Lim, Y. A. L., Chai, H. C., Chua, K. H., & Lee, P. C. (2020). Genetic diversity of circumsporozoite protein in Plasmodium knowlesi isolates from Malaysian Borneo and Peninsular Malaysia. Malaria Journal, 19(1), 7. doi: 10.1186/s12936-020-03451-x
  5. Chua, K. H., Tan, E. W., Chai, H. C., Puthucheary, S. D., Lee, P. C., & Puah, S. M. (2020). Rapid identification of melioidosis agent by an insulated isothermal PCR on a field-deployable device. PeerJ, 8, 16. doi: 10.7717/peerj.9238
  6. Tan, T. K., Lim, Y. A. L., Chua, K. H., Chai, H. C., Low, V. L., Bathmanaban, P., . . . Panchadcharam, C. (2020). Characterization of benzimidazole resistance inHaemonchus contortus: integration of phenotypic, genotypic and proteomic approaches. Parasitology Research, 119(9), 2851-2862. doi: 10.1007/s00436-020-06790-5
  7. Goh, X. T., Chua, K. H., Vythilingam, I., Lee, P. C., Tan, T. C., Yap, N. J., . . . Lim, Y. A. L. (2019). Genetic diversity of Merozoite Surface Protein-1 gene block 2 allelic types in Plasmodium falciparum isolates from Malaysia and Thailand. Tropical Biomedicine, 36(1), 70-80.
Others
  1. Chong, E., Neoh, J., Lau, T. Y., Lim, Y. A., Chai, H. C., Chua, K. H., & Lee, P. C. (2020). Genetic diversity of circumsporozoite protein in Plasmodium knowlesi isolates from Malaysian Borneo and Peninsular Malaysia. Malaria journal, 19(1), 377.
  2. KH Chua, YY Ooh and HC Chai (2016). TNFSF4 polymorphisms are associated with systemic lupus erythematosus in the Malaysian population. International Journal of Immunogenetics 43: 303-309
  3. Kek Heng Chua, Ping Chin Lee & Hwa Chia Chai. 2016. Development of insulated isothermal PCR for rapid on- site malaria detection. Malaria Journal 15:134
  4. Kek Heng Chua, Siew Chee Lim, Ching Ching Ng, Ping Chin Lee, Yvonne Ai Lian Lim, Tze Pheng Lau, Hwa Chia Chai. Development of High Resolution Melting Analysis for the Diagnosis of Human Malaria. Scientific Reports. 2015;5:15671.
  5. Chai HC, Chua KH, Lim SK, Phipps ME. Insight into gene polymorphisms involved in toll-like receptor/interferon signalling pathways for systemic lupus erythematosus in South East Asia. J Immunol Res. 2014;2014:529167. doi:10.1155/2014/529167
  6. Lau, T.P., Roslani, A.C., Lian, L.H., Chai, H.C., Lee, P.C., Hilmi, I., Goh, K.L., Chua, K.H. (2014). Pair-wise comparison analysis of differential expression of mRNAs in early and advanced stage primary colorectal adenocarcinomas. BMJ Open, 4(8),e004930.

RESEARCH INTEREST

  • Molecular Diagnosis of Malaria
  • Proteomic and immunogenetic analysis of systemic lupus erythematosus

RESEARCH PROJECT

National
  1. 2018 - 2018, Fundamental Research Grant Scheme (FRGS)
    Establishing 3D human skin equivalent for investigating pathogenesis of vitiligo (External Grant Application) ( Principal Investigator(PI))
  2. 2017 - 2018, UM Prototype grant
    BP Detect ( Consultant)
International
  1. 2018 - 2018, 350 Research Grants (Merck)
    Morphological and protein changes in melanocytes and keratinocytes in the progression to vitiligo (External Grant Application) ( Principal Investigator(PI))

PAPER PRESENTED

INVITED SPEAKER
  1. Molecular Techniques, Genetic studies short workshop: Myanmar-UM, Department of Biomedical Science (International) (17 Apr 2018 - 18 Apr 2018)
POSTER PRESENTER
  1. Human Plasmodium falciparum Detection: Anywhere, Anytime, 54th Annual Scientific Conference of the Malaysian Society of Parasitology and Tropical Medicine (MSPTM) , Malaysian Society of Parasitology and Tropical Medicine (MSPTM) (International) (14 Mar 2018 - 15 Mar 2018)
  2. Development of on-site diagnostic tool of human Plasmodium species, 3rd Pan-Asian Biomedical Science Conference, ASIA-International Biomedical Science Consortium (Others) (07 Dec 2016 - 08 Nov 2016)
  3. Development of on-site diagnostic tool of human Plasmodium species, XIX International Congress for Tropical Medicine and Malaria 2016, Australian Society for Parasitology (International) (18 Sep 2016 - 22 Sep 2016)

ACADEMIC/PROF. SERVICES

Evaluation
  1. (2018) Evaluation of two immunoassays as compared to Microscopic Agglutination Test (MAT) for early diagnosis of Leptospira sp. , (Reviewer)
  2. (2018) Chemical Modification of Selected Peptide Drugs for Enhanced Therapy of Type II Diabetes Mellitus , (Internal Examiner)
  3. (2018) New high-resolution melting analysis for the detection and identification of Plasmodium in human and Anopheles vectors of malaria , (Reviewer)
  4. (2018) Effects of Quinazoline Derivatives on Non Small Lung Cancer Xenografted in Zebrafish Embryos , (Internal Examiner)
  5. (2018) Study of Tear Proteome and Corneal Co-Cultures in Keratoconus , (Internal Examiner)
  6. (2016) Estimating the Origin and Transmission of Recently Emerged HIV-1 Recombinants in Malaysia and Singapore (Master thesis), (Internal Examiner)
  7. (2016) Molecular Epidemiology of Human Parainfluenza Viruses Associated with Acute Respiratory Illnesses in Kuala Lumpur, Malaysia (Master project abstract), (Reviewer)
  8. (2016) Rapid and high throughput molecular identification of diverse mosquito species by high resolution melting analysis (in F1000Research), (Reviewer)
  9. (2016) Genetic Researches Among Malaysian Famiial Hypercholesterolemic Population, (Reviewer)

SUPERVISION

Postgraduate Student
PhD/ Doctoral
  1. (2017) Characterization and Virulence Study of Pseudomonas Aeruginosa Isolated from Clinical and Enviromental Specimens., LIEW SIEW MUN

TEACHING

Bachelor
  1. (2020) MIC2011 - Molecular Techniques
  2. (2019) MIC2008 - Pathophysiology I