Curriculum Vitae

DR. HAZWANI MAT SAAD

Senior Lecturer
  • Office of The Executive Director
    Centre for Foundation Studies in Science
  • hazwanimatsaad
  • 0379675916

AREAS OF EXPERTISE

  • CELL CULTURE-BASED DRUG TESTING
  • COSMECEUTICAL
    Skin-lightening; Natural products

ACADEMIC QUALIFICATION

  • PhD(Bio), (Biologi / Biokimia / Mikrobiologi / Kimia Organik)
    Universiti Malaya (UM)
  • M.Sc.Bio, (Sains Biologi & Kimia)
    Universiti Malaya (UM)
  • Ba.Sc, (Biochemistry)
    Universiti Malaya (UM)

MEMBERSHIPS

  • MALAYSIAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, MEMBER
    2023 to 2024 (National)

PUBLICATIONS

Article in Journal
WoS
  1. Pungut, Nur Amira Solehah; Tan, Chun Hoe; Saad, Hazwani Mat; Sim, Kae Shin; Tiong, Sheena Yin Xin; Ang, Chee Wei; Gan, Chun Hau; Kong, Kien Voon; Tan, Kong Wai (2023). A new cinnamaldehyde-rhodamine based dual chemosensor for Cu2+and Fe3+and its applicability in live cell imaging, JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY. 438. doi:10.1016/j.jphotochem.2023.114540
  2. Saad, Hazwani Mat; Tan, Chun Hoe; Manickam, Sugumaran; Lim, Siew Huah; Sim, Kae Shin (2023). Artocarpus heterophyllus Lam. Stem Bark Inhibits Melanogenesis through Regulation of ROS, cAMP, and MAPK Pathways, SAINS MALAYSIANA. 52(2), 441-465. doi:10.17576/jsm-2023-5202-10
  3. Chan, Wei Chuen; Saad, Hazwani Mat; Sim, Kae Shin; Lee, Vannajan Sanghiran; Tan, Kong Wai (2022). A rapid turn-on dual functional rhodamine B probe for aluminum (III) and copper (II) that can be utilised as a molecular logic gate and in water analysis, JOURNAL OF MOLECULAR STRUCTURE. 1254. doi:10.1016/j.molstruc.2022.132337
  4. Chan, W. C., Saad, H. M., Sim, K. S., Lee, V. S., Ang, C. W., Yeong, K. Y., & Tan, K. W. (2021). A rhodamine based chemosensor for solvent dependent chromogenic sensing of cobalt (II) and copper (II) ions with good selectivity and sensitivity: Synthesis, filter paper test strip, DFT calculations and cytotoxicity. Spectrochimica Acta Part a-Molecular and Biomolecular Spectroscopy, 262, 14. doi: 10.1016/j.saa.2021.120099
  5. Cheah, P. W., Heng, M. P., Saad, H. M., Sim, K. S., & Tan, K. W. (2021). Specific detection of Cu2+ by a pH-independent colorimetric rhodamine based chemosensor. Optical Materials, 114, 8. doi: 10.1016/j.optmat.2021.110990
  6. Pungut, N. A. S., Heng, M. P., Saad, H. M., Sim, K. S., Lee, V. S., & Tan, K. W. (2021). From one to three, modifications of sensing behavior with solvent system: DFT calculations and real-life application in detection of multianalytes (Cu2+, Ni2+ and Co2+) based on a colorimetric Schiff base probe. Journal of Molecular Structure, 1238, 9. doi: 10.1016/j.molstruc.2021.130453
  7. Pungut, N. A. S., Saad, H. M., Sim, K. S., & Tan, K. W. (2021). A turn on fluorescent sensor for detecting Al3+ and colorimetric detection for Cu2+: Synthesis, cytotoxicity and on-site assay kit. Journal of Photochemistry and Photobiology a-Chemistry, 414, 9. doi: 10.1016/j.jphotochem.2021.113290
  8. Saad, H. M., Rahman, S., Navanesan, S., Tan, C. H., Manickam, S., Abd Malek, S. N., & Sim, K. S. (2021). Evaluation of antioxidant activity and phytochemical composition of Baeckea frutescens and Leptospermum javanicum essential oils. South African Journal of Botany, 141, 474-479. doi: 10.1016/j.sajb.2021.06.005
  9. Saad, H. M., Tan, C. H., Lim, S. H., Manickam, S., & Sim, K. S. (2021). Evaluation of anti-melanogenesis and free radical scavenging activities of five Artocarpus species for cosmeceutical applications. Industrial Crops and Products, 161, 10. doi: 10.1016/j.indcrop.2020.113184
  10. Heng, Mok Piew; Tan, Chun Hoe; Saad, Hazwani Mat; Sim, Kae Shin; Tan, Kong Wai (2020). Mitochondria -dependent apoptosis inducer: Testosterone-N-4- ethylthiosemicarbazonate and its metal complexes with selective cytotoxicity towards human colorectal carcinoma cell line (HCT 116), INORGANICA CHIMICA ACTA. 507. doi:10.1016/j.ica.2020.119581
  11. Yeap, Joanne Soon-Yee; Saad, Hazwani Mat; Tan, Chun-Hoe; Sim, Kae-Shin; Lim, Siew-Huah; Low, Yun-Yee; Kam, Toh-Seok (2019). Macroline-Sarpagine Bisindole Alkaloids with Antiproliferative Activity from Alstonia penangiana, JOURNAL OF NATURAL PRODUCTS. 82(11), 3121-3132. doi:10.1021/acs.jnatprod.9b00712
  12. Saad, Hazwani Mat; Sim, Kae Shin; Tan, Yee Shin (2018). Antimelanogenesis and Anti-Inflammatory Activity of Selected Culinary-Medicinal Mushrooms, INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS. 20(2), 141-153. doi:10.1615/IntJMedMushrooms.2018025463
Others
  1. Almayahi, B. A., Sani, S. F. A., Tajuddin, H. A., Saad, H. M., Alhasan, A., & Sim, K. S. (2025). Structural and Functional Characterization of Gamma-Irradiation-Enhanced Nanocomposites for Colorectal Cancer Therapy. Journal of Molecular Structure, 1321, 139859.
  2. Marlina A, Misran M, Ndruru STCL, Mat Saad H, Sim KS. 2024. Development and Characterization of Tannic Acid-Modified PVA-ÎșCarrageenan Gel for Sustained Release of Lidocaine. ChemistrySelect, 9, e202400387.

RESEARCH PROJECT

National
  1. 2023 - 2025, Bantuan Khas Penyelidikan (BKP Special)
    Revealing The Selected Indigenous Tropical Fruit Trees for Potential Skin-lightening Cosmeceutical Application ( Principal Investigator(PI))