Curriculum Vitae

DR. HASSAN ALMOUSTAFA

Lecturer
  • Department of Pharmacology
    Faculty of Medicine
  • hasan85
  • 01123182891

BIOGRAPHY

Dr. Hassan Almoustafa is currently working as a Lecturer at Department of Pharmacology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia. Before joining UM faculty of Medicine as a PhD student he practiced Community Pharmacy in Syria while obtaining a masters degree in biomedical engineering from the University of Aleppo. He obtained his PhD from Faculty of Medicine, University of Malaya in 2021 where he had his Post Doctoral Research Fellowship. His area of expertise is drug delivery and his research interests are Nanomedicine in cancer treatment particulary polymeric nanoparticle formulations and the industrial scale up of Nanotechnology based medications.

ACADEMIC QUALIFICATION

  • PhD, (Philosophy)
    Universiti Malaya
  • M.BE, (Kejuruteraan Bioperubatan)
    University of Aleppo
  • B.Pharm, (PHARMACEUTICAL CHEMISTRY)
    University of Aleppo

ADMINISTRATIVE DUTIES

  • Coordinator
    01 Nov 2024 - 31 Oct 2026 (Department of Pharmacology, Faculty of Medicine)
  • Course Coordinator
    09 Oct 2023 - 08 Oct 2025 (University Malaya)

MEMBERSHIPS

  • ??? MEMBERSHIP TYPE: ANNUAL ??? MEMBERSHIP NUMBER: MYSEV-AN-00016/24 ??? EXPIRY DATE: 31ST DECEMBER 2025, MEMBER
    2024 to 2025 (National)
  • CORE MEMBER OF THE UNIVERSITI MALAYA RESEARCH CENTRE FOR BIOPHARMACEUTICALS AND ADVANCED THERAPEUTICS (UBAT), MEMBER
    2024 to 2025 (University)

AWARD AND STEWARDSHIP

  • Postdoctoral Research Fellowship
    2022, Universiti Malaya,  (University)
  • Malaysian International Scholarship (Mis)
    2014, Ministry of Education Malaysia,  (National)

PUBLICATIONS

Article in Journal
WoS
  1. Alshehade, Salah Abdalrazak; Almoustafa, Hassan A.; Alshawsh, Mohammed Abdullah; Chik, Zamri (2024). Flow cytometry-based quantitative analysis of cellular protein expression in apoptosis subpopulations: A protocol, HELIYON. 10(13). doi:10.1016/j.heliyon.2024.e33665
  2. Azad, Abul Kalam; Lai, Joanne; Sulaiman, Wan Mohd Azizi Wan; Almoustafa, Hassan; Alshehade, Salah Abdalrazak; Kumarasamy, Vinoth; Subramaniyan, Vetriselvan (2024). The Fabrication of Polymer-Based Curcumin-Loaded Formulation as a Drug Delivery System: An Updated Review from 2017 to the Present, PHARMACEUTICS. 16(2). doi:10.3390/pharmaceutics16020160
  3. Almoustafa, Hassan A.; Alshawsh, Mohammed Abdullah; Al-Suede, Fouad Saleih R.; Alshehade, Salah Abdulrazak; Majid, Amin Malik Shah Abdul; Chik, Zamri (2023). The Chemotherapeutic Efficacy of Hyaluronic Acid Coated Polymeric Nanoparticles against Breast Cancer Metastasis in Female NCr-Nu/Nu Nude Mice, POLYMERS. 15(2). doi:10.3390/polym15020284
  4. Alshehade, Salah Abdalrazak; Al Zarzour, Raghdaa Hamdan; Mathai, Michael; Giribabu, Nelli; Seyedan, Atefehalsadat; Kaur, Gurjeet; Al-Suede, Fouad Saleih Resq; Majid, Amin Malik Shah Abdul; Murugaiyah, Vikneswaran; Almoustafa, Hassan; Alshawsh, Mohammed Abdullah (2023). Orthosiphon aristatus (Blume) Miq Alleviates Non-Alcoholic Fatty Liver Disease via Antioxidant Activities in C57BL/6 Obese Mice and Palmitic-Oleic Acid-Induced Steatosis in HepG2 Cells, PHARMACEUTICALS. 16(1). doi:10.3390/ph16010109
  5. Alshehade, Salah; Alshawsh, Mohammed Abdullah; Murugaiyah, Vikneswaran; Asif, Muhammad; Alshehade, Omayma; Almoustafa, Hassan; Al Zarzour, Raghdaa Hamdan (2022). The role of protein kinases as key drivers of metabolic dysfunction-associated fatty liver disease progression: New insights and future directions, LIFE SCIENCES. 305. doi:10.1016/j.lfs.2022.120732
  6. Almoustafa, H. A., Alshawsh, M. A., & Chik, Z. (2021). Targeted polymeric nanoparticle for anthracycline delivery in hypoxia-induced drug resistance in metastatic breast cancer cells. Anti-Cancer Drugs, 32(7), 745-754. doi: 10.1097/cad.0000000000001065
  7. Almoustafa, Hassan A.; Alshawsh, Mohammed A.; Chik, Zamri (2017). Technical aspects of preparing PEG-PLGA nanoparticles as carrier for chemotherapeutic agents by nanoprecipitation method, INTERNATIONAL JOURNAL OF PHARMACEUTICS. 533(1), 275-284. doi:10.1016/j.ijpharm.2017.09.054
ESCI
  1. Azad, Abul Kalam; Sulaiman, Wan Mohd Azizi Wan; Almoustafa, Hassan; Dayoob, Mohamad; Kumarasamy, Vinoth; Subramaniyan, Vetriselvan; Alshehri, Jamilah M.; Khan, Azmat Ali (2024). A dataset of microstructure features of electro-hydrodynamic assisted 5-fluorouracil-grafted alginate microbeads and physicochemical properties for effective colon targeted carriers drug delivery, DATA IN BRIEF. 53. doi:10.1016/j.dib.2024.110202
Scopus
  1. Alshehade S.A., Almoustafa H.A., Alshawsh M.A., Chik Z. (2024). Flow cytometry-based quantitative analysis of cellular protein expression in apoptosis subpopulations: A protocol, Heliyon. 10(13). doi:10.1016/j.heliyon.2024.e33665
  2. Azad A.K., Lai J., Sulaiman W.M.A.W., Almoustafa H., Alshehade S.A., Kumarasamy V., Subramaniyan V. (2024). The Fabrication of Polymer-Based Curcumin-Loaded Formulation as a Drug Delivery System: An Updated Review from 2017 to the Present, Pharmaceutics. 16(2). doi:10.3390/pharmaceutics16020160
  3. Almoustafa H.A., Alshawsh M.A., Al-Suede F.S.R., Alshehade S.A., Abdul Majid A.M.S., Chik Z. (2023). The Chemotherapeutic Efficacy of Hyaluronic Acid Coated Polymeric Nanoparticles against Breast Cancer Metastasis in Female NCr-Nu/Nu Nude Mice, Polymers. 15(2). doi:10.3390/polym15020284
  4. Alshehade S.A., Al Zarzour R.H., Mathai M., Giribabu N., Seyedan A., Kaur G., Al-Suede F.S.R., Majid A.M.S.A., Murugaiyah V., Almoustafa H., Alshawsh M.A. (2023). Orthosiphon aristatus (Blume) Miq Alleviates Non-Alcoholic Fatty Liver Disease via Antioxidant Activities in C57BL/6 Obese Mice and Palmitic Oleic Acid-Induced Steatosis in HepG2 Cells, Pharmaceuticals. 16(1). doi:10.3390/ph16010109
  5. Alshehade S., Alshawsh M.A., Murugaiyah V., Asif M., Alshehade O., Almoustafa H., Al Zarzour R.H. (2022). The role of protein kinases as key drivers of metabolic dysfunction-associated fatty liver disease progression: New insights and future directions, Life Sciences. 305. doi:10.1016/j.lfs.2022.120732
  6. Almoustafa H.A., Alshawsh M.A., Chik Z. (2017). Technical aspects of preparing PEG-PLGA nanoparticles as carrier for chemotherapeutic agents by nanoprecipitation method, International Journal of Pharmaceutics. 533(1), 275-284. doi:10.1016/j.ijpharm.2017.09.054
Article in Proceeding
  1. Chik, Z., Alshawsh, M. A. M., & Almoustafa, H. (2018). Preparation of Targeted PEG-PLGA Nanoparticles for the Treatment of Cancer Metastasis. In Proceedings for Annual Meeting of The Japanese Pharmacological Society WCP2018 (The 18th World Congress of Basic and Clinical Pharmacology) (pp. PO4-6). Japanese Pharmacological Society.

RESEARCH PROJECT

National
  1. 2024 - 2025, Partnership Grant
    Modelling and Investigating Effect of Therapeutic-Induced Senescence As Mechanism Of Cancer Stem Cell Plasticity In Cancer ( Co-Researcher)
University
  1. 2024 - 2026, Bantuan Khas Penyelidikan (BKP Special)
    Physicochemical Characteristics, In Silico Behaviour and In Vitro Evaluation of a Paclitaxel Lipid-Polymer Hybrid Nanoparticles for Enhanced Breast Cancer Treatment ( Principal Investigator(PI))
  2. 2024 - 2026, Bantuan Khas Penyelidikan (BKP Special)
    Enhancing Diabetes Literacy Materials: A Critical Multimodal Analysis Of Diabetes-related Educational And Promotional Discourse In Malaysia ( Co-Researcher)
  3. 2023 - 2025, University Grant
    A Novel Paclitaxel PEG-PHA Nanoparticle Formulation for the Treatment of Breast Cancer: Preparation, Physicochemical Characterization, and InVitro Efficacy studies ( Co-Researcher)

ACADEMIC/ PROF. SERVICES

Evaluation
  1. (2024) Phd Candidature Defense for The Student Lim Xin Yun (17092744/2), University, (Internal Examiner)
  2. (2024) Effect of Pegylation Method On The Critical Quality Attributes of Nano-Graphene Oxide as a Carrier for Doxorubicin: a Comparative in Vitro Study Pharmaceutical Development and Technology, International, (Reviewer)
  3. (2024) Phd's Candidature Defence - Puvanan Karunanithi 17043480/2) Was Held On Fri Aug 30, 2024 11am, University, (Internal Examiner)

SUPERVISION

Postgraduate Student
  1. (2024) NANOMEDICINE IN CANCER THERAPY, ALHASAN ALI JABBAR
  2. (2024) UNLOCKING THE POTENTIAL OF PHA FROM PSEUDOMONAS PUTIDA: COMPOSITION OPTIMIZATION, PHYSICOCHEMICAL CHARACTERIZATION, AND TOXICITY EVALUATION FOR BREAST CANCER, NEGAR AHMADI
  3. (2024) PHARMACOKINETICS AND BIODISTRIBUTION STUDIES OF A NOVEL DOXORUBICIN AND PACLITAXEL POLYMERIC NANOPARTICLE FORMULATIONS IN SPRAGUE DAWLEY (SD) RATS, DANUSHA MICHELLE
Under Graduate Students
  1. (2024) Assessment of Bacterial Growth Levels on 3D Printed Prosthetic Limb Surface After Chemical Coating (Universiti Kuala Lumpur)
  2. (2024) In-Vitro Cytotoxicity of CD44 Targeted Nanoparticles Against Hepatocellular Carcinoma (Universiti Kuala Lumpur)
  3. (2024) Assessment of Bacterial Growth Levels on 3D Printed Prosthetic Limb Surface After Chemical Postprocessing. (Universiti Kuala Lumpur)
  4. (2024) Investigating the Effects of Radiation in Promoting Cancer Stemness in Hepatocellular Carcinoma Cell Line
  5. (2024) Development of Radiation-Induced Resistant Hepatocellular Carcinoma Cell Line

TEACHING

Master
  1. (2024) MQF7003 - Foundations of Research Ethics
  2. (2024) MQF7005 - Responsible Conduct of Research
Bachelor
  1. (2024) MIC3019 - Applied Pharmacology and Therapeutics
  2. (2024) MIX3003 - Drugs: from Target to Market
  3. (2024) MIC2013 - Laboratory Animal Science
  4. (2024) MID1009 - Pharmacology in Nursing
  5. (2024) PBL - Prblem Based Learning
  6. (2024) MIA 2001 - Universiti Malaya Medical Programme (Ummp)

PATENT/ IPR

  • A TARGETED CHEMOTHERAPEUTIC DRUG DELIVERY SYSTEM AND METHOD FOR PRODUCING THEREOF
    PATENT

COURSE ATTENDED

Internal/ External Course
INTERNAL COURSE- ORGANIZED BY PTJ
  1. A PRIMER FOR WORKPLACE-BASED ASSESSMENTS(NOV2022), Microsoft Teams(Fully Online) (29 Nov 2022 - 29 Nov 2022)
  2. PROBLEM BASED LEARNING(NOV 2022), Cube, Aras 4, Fakulti Perubatan, UM (23 Nov 2022 - 24 Nov 2022)
  3. MOHRE FACULTY RETREAT 2023, Aloft Kuala Lumpur (21 Sep 2023 - 21 Sep 2023)
  4. ESSENTIAL OF TEACHING & LEARNING FOR HEALTH PROFESSIONALS(FEBRUARY 2023), Microsoft Teams Online (22 Feb 2023 - 23 Feb 2023)
  5. MOHRE FACULTY DEVELOPMENT WORKSHOP 2024, Aloft, Kl Sentral (08 Jan 2024 - 09 Jan 2024)
  6. FOUNDATIONS OF ASSESSMENT FOR HEALTH PROFESSIONALS WORKSHOP ON THE 17TH JANUARY 2024, Bilik Fakulti, Aras 5, Fakulti Perubatan, Universiti Malaya. (17 Jan 2024 - 17 Jan 2024)
  7. EMERALD REASEARCH AND SUPERVISION 1/2024, Bangunan Hir, UM (27 Feb 2024 - 29 Feb 2024)
  8. RESEARCH INDUCTION WORKSHOP FOR EARLY CAREER RESEARCHERS (ECR), FACULTY OF MEDICINE, UM 2024, Cube, Aras 4, Fakulti Perubatan (24 Apr 2024 - 24 Apr 2024)
  9. MOHRE FACULTY DEVELOPMENT WORKSHOP (FDW) CURRICULUM REVIEW AND EVALUATION WORKSHOP , Le Meridien, Kuala Lumpur (10 Sep 2024 - 10 Sep 2024)
External Course
INTERNATIONAL
  1. Understanding Cancer Metastasis, Coursera (01 Apr 2021 - 13 Apr 2021)
  2. Introduction to Breast Cancer, Coursera (10 Apr 2021 - 23 Apr 2021)
  3. Basics of Extracellular Vesicles, Coursera (23 Dec 2021 - 09 Jan 2022)
  4. Precision Medicine, Coursera (11 May 2021 - 17 May 2021)
  5. Nanotechnology: A Maker s Course, Online (01 Jan 2022 - 12 Nov 2022)