Curriculum Vitae

DR. HASSAN ALMOUSTAFA

Lecturer
  • Department of Pharmacology
    Faculty of Medicine

BIOGRAPHY

Dr. Hassan Almoustafa is currently working as a Lecturer at Department of Pharmacology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia. Before joining UM faculty of Medicine as a PhD student he practiced Community Pharmacy in Syria while obtaining a masters degree in biomedical engineering from the University of Aleppo. He obtained his PhD from Faculty of Medicine, University of Malaya in 2021 then he had 1 year as Post Doctoral Research Fellowship. His area of expertise is drug delivery and his research interests are Nanomedicine in cancer treatment particulary polymeric nanoparticle formulations and the industrial scale up of Nanotechnology based medications.

AREAS OF EXPERTISE

  • THERAPEUTICS
    Cancer, Chemotherapy
  • PHARMACEUTICAL TECHNOLOGY
    Cancer Nanomedicine, Polymeric nanoparticles, Nanoprecipitation, Industrial scale up

ACADEMIC QUALIFICATION

  • PhD, (Philosophy)
    Universiti Malaya
  • M.BE, (Kejuruteraan Bioperubatan)
    University of Aleppo
  • B.Pharm, (Pharmaceutical Chemistry)
    University of Aleppo

AWARD AND STEWARDSHIP

  • Postdoctoral Research Fellowship
    Universiti Malaya, 2022 (University)
  • Malaysian International Scholarship (MIS)
    Ministry of Education Malaysia, 2014 (National)

PUBLICATIONS

Article in Journal
WoS
  1. Almoustafa, Hassan A.; Alshawsh, Mohammed Abdullah; Al-Suede, Fouad Saleih R.; Alshehade, Salah Abdulrazak; Majid, Amin Malik Shah Abdul; Chik, Zamri (2023). The Chemotherapeutic Efficacy of Hyaluronic Acid Coated Polymeric Nanoparticles against Breast Cancer Metastasis in Female NCr-Nu/Nu Nude Mice, POLYMERS. 15(2). doi:10.3390/polym15020284
  2. Alshehade, Salah Abdalrazak; Al Zarzour, Raghdaa Hamdan; Mathai, Michael; Giribabu, Nelli; Seyedan, Atefehalsadat; Kaur, Gurjeet; Al-Suede, Fouad Saleih Resq; Majid, Amin Malik Shah Abdul; Murugaiyah, Vikneswaran; Almoustafa, Hassan; Alshawsh, Mohammed Abdullah (2023). Orthosiphon aristatus (Blume) Miq Alleviates Non-Alcoholic Fatty Liver Disease via Antioxidant Activities in C57BL/6 Obese Mice and Palmitic-Oleic Acid-Induced Steatosis in HepG2 Cells, PHARMACEUTICALS. 16(1). doi:10.3390/ph16010109
  3. Alshehade, Salah; Alshawsh, Mohammed Abdullah; Murugaiyah, Vikneswaran; Asif, Muhammad; Alshehade, Omayma; Almoustafa, Hassan; Al Zarzour, Raghdaa Hamdan (2022). The role of protein kinases as key drivers of metabolic dysfunction-associated fatty liver disease progression: New insights and future directions, LIFE SCIENCES. 305. doi:10.1016/j.lfs.2022.120732
  4. Almoustafa, H. A., Alshawsh, M. A., & Chik, Z. (2021). Targeted polymeric nanoparticle for anthracycline delivery in hypoxia-induced drug resistance in metastatic breast cancer cells. Anti-Cancer Drugs, 32(7), 745-754. doi: 10.1097/cad.0000000000001065
  5. Almoustafa, Hassan A.; Alshawsh, Mohammed A.; Chik, Zamri (2017). Technical aspects of preparing PEG-PLGA nanoparticles as carrier for chemotherapeutic agents by nanoprecipitation method, INTERNATIONAL JOURNAL OF PHARMACEUTICS. 533(1), 275-284. doi:10.1016/j.ijpharm.2017.09.054
Scopus
  1. Azad A.K., Lai J., Sulaiman W.M.A.W., Almoustafa H., Alshehade S.A., Kumarasamy V., Subramaniyan V. (2024). The Fabrication of Polymer-Based Curcumin-Loaded Formulation as a Drug Delivery System: An Updated Review from 2017 to the Present, Pharmaceutics. 16(2). doi:10.3390/pharmaceutics16020160
  2. Almoustafa H.A., Alshawsh M.A., Al-Suede F.S.R., Alshehade S.A., Abdul Majid A.M.S., Chik Z. (2023). The Chemotherapeutic Efficacy of Hyaluronic Acid Coated Polymeric Nanoparticles against Breast Cancer Metastasis in Female NCr-Nu/Nu Nude Mice, Polymers. 15(2). doi:10.3390/polym15020284
  3. Alshehade S.A., Al Zarzour R.H., Mathai M., Giribabu N., Seyedan A., Kaur G., Al-Suede F.S.R., Majid A.M.S.A., Murugaiyah V., Almoustafa H., Alshawsh M.A. (2023). Orthosiphon aristatus (Blume) Miq Alleviates Non-Alcoholic Fatty Liver Disease via Antioxidant Activities in C57BL/6 Obese Mice and Palmitic Oleic Acid-Induced Steatosis in HepG2 Cells, Pharmaceuticals. 16(1). doi:10.3390/ph16010109
  4. Alshehade S., Alshawsh M.A., Murugaiyah V., Asif M., Alshehade O., Almoustafa H., Al Zarzour R.H. (2022). The role of protein kinases as key drivers of metabolic dysfunction-associated fatty liver disease progression: New insights and future directions, Life Sciences. 305. doi:10.1016/j.lfs.2022.120732
  5. Almoustafa H.A., Alshawsh M.A., Chik Z. (2017). Technical aspects of preparing PEG-PLGA nanoparticles as carrier for chemotherapeutic agents by nanoprecipitation method, International Journal of Pharmaceutics. 533(1), 275-284. doi:10.1016/j.ijpharm.2017.09.054
Article in Proceeding
  1. Chik, Z., Alshawsh, M. A. M., & Almoustafa, H. (2018). Preparation of Targeted PEG-PLGA Nanoparticles for the Treatment of Cancer Metastasis. In Proceedings for Annual Meeting of The Japanese Pharmacological Society WCP2018 (The 18th World Congress of Basic and Clinical Pharmacology) (pp. PO4-6). Japanese Pharmacological Society.

PATENT/IPR

  • A TARGETED CHEMOTHERAPEUTIC DRUG DELIVERY SYSTEM AND METHOD FOR PRODUCING THEREOF
    PATENT

COURSE ATTENDED

External Course
INTERNATIONAL
  1. Understanding Cancer Metastasis, Coursera (01 Apr 2021 - 13 Apr 2021)
  2. Introduction to Breast Cancer, Coursera (10 Apr 2021 - 23 Apr 2021)
  3. Basics of Extracellular Vesicles, Coursera (23 Dec 2021 - 09 Jan 2022)
  4. Precision Medicine, Coursera (11 May 2021 - 17 May 2021)
  5. Nanotechnology: A Maker s Course, Online (01 Jan 2022 - 12 Nov 2022)
Internal / External Course
INTERNAL COURSE- ORGANIZED BY PTJ
  1. A PRIMER FOR WORKPLACE-BASED ASSESSMENTS(NOV2022), Microsoft Teams(Fully Online) (29 Nov 2022 - 29 Nov 2022)
  2. PROBLEM BASED LEARNING(NOV 2022), Cube, Aras 4, Fakulti Perubatan, UM (23 Nov 2022 - 24 Nov 2022)
  3. ESSENTIAL OF TEACHING & LEARNING FOR HEALTH PROFESSIONALS(FEBRUARY 2023), Microsoft Teams Online (22 Feb 2023 - 23 Feb 2023)
  4. MOHRE FACULTY RETREAT 2023, Aloft Kuala Lumpur (21 Sep 2023 - 21 Sep 2023)
  5. MOHRE FACULTY DEVELOPMENT WORKSHOP 2024, Aloft, Kl Sentral (08 Jan 2024 - 09 Jan 2024)
  6. FOUNDATIONS OF ASSESSMENT FOR HEALTH PROFESSIONALS WORKSHOP ON THE 17TH JANUARY 2024, Bilik Fakulti, Aras 5, Fakulti Perubatan, Universiti Malaya. (17 Jan 2024 - 17 Jan 2024)
  7. EMERALD REASEARCH AND SUPERVISION 1/2024, Bangunan Hir, UM (27 Feb 2024 - 29 Feb 2024)