Curriculum Vitae

DR. FRANCIS TIENG YEW FU

Senior Lecturer
  • Department of Oncology Clinical
    Faculty of Medicine
  • francistieng
  • 0379673021

AREAS OF EXPERTISE

  • SINGLE CELL GENOMES
    Life Sciences, Biological Sciences, Genes And Genomes Biology
  • CANCER CELL BIOLOGY
    Medical And Health Sciences, Health Sciences, Biomedical Sciences

ACADEMIC QUALIFICATION

  • PhD(CANCER), (CANCER)
    Universiti Kebangsaan Malaysia (ukm)
  • M.Sc(MEDICAL BIOTECHNOLOGY), (Medical Biotechnology)
    Universiti Putra Malaysia (upm)
  • B.Sc(BIOMEDICAL SCIENCES), (Biomedical Science)
    Universiti Putra Malaysia (upm)

ADMINISTRATIVE DUTIES

  • Course Director of Clinical Oncology in the National Postgraduate Medical Curriculum (NPMC) of Malaysia
    06 Mar 2025 - 05 Mar 2027 (National)
  • UM X Curie Masterclass of Cancer Molecular Biology 2025 (invited two international speakers)
    03 Jan 2025 - 14 Feb 2025 (International)
  • Committee Members
    03 Dec 2024 - 03 Dec 2024 (International)

MEMBERSHIPS

  • REVIEW EDITOR IN FRONTIERS IN IMMUNOLOGY (Q1, IF=5.7), EDITORIAL BOARD
    Since 2025 (International)
  • REVIEW EDITOR, EDITORIAL BOARD
    Since 2024 (International)
  • ASSOCIATE MEMBER OF THE MALAYSIAN ONCOLOGICAL SOCIETY (MOS), MEMBER
    2024 to 2025 (National)
  • MEMBER OF THE ASSOCIATION FOR SINGLE CELL ANALYSIS (ASCA), MEMBER
    Since 2023 (International)
  • MEMBER OF ASIA PACIFIC MICROBIOME & BIOMEDICAL RESEARCH NETWORK (MAMB), MEMBER
    Since 2022 (International)

PUBLICATIONS

Article in Journal
  1. Tieng, F.Y.F., Lee, LH. & Ab Mutalib, NS. Single-cell RNA-sequencing of circulating tumour cells: A practical guide to workflow and translational applications. Cancer Metastasis Rev 44, 75 (2025). https://doi.org/10.1007/s10555-025-10293-z
  2. Norhisan, N. N., Baharudin, R., Bakarurraini, N. Q. R., Shahri, N. A. A. M., Tieng, F. Y. F., Ismail, I., Abdullah-Zawawi, M.-R., Lee, L.-H., & Mutalib, N. S. A. (2024). Decoding the Methylation Patterns of ABC Transporters in Colorectal Cancer. Progress In Microbes & Molecular Biology, 7(1), Article 1. https://doi.org/10.36877/pmmb.a0000450
  3. Mohd Yunos, R. I., Ab Mutalib, N.-S., Khoo, J., Saidin, S., Ishak, M., Syafruddin, S. E., Tieng, F. Y. F., Md Yusof, N. F., Abd Razak, M. R., Mahamad Nadzir, N., Abu, N., Rose, I. M., Sagap, I., Mazlan, L., & Jamal, R. (2023). Whole genome sequencing of Malaysian colorectal cancer patients reveals specific druggable somatic mutations. Frontiers in Molecular Biosciences, 9. https://www.frontiersin.org/articles/10.3389/fmolb.2022.997747
  4. Tieng, F., Abdullah-Zawawi, M.-R., Shahri, N., Mohamed-Hussein, Z.-A., Lee, L.-H., & Ab Mutalib, N.-S. (2023). A Hitchhiker’s guide to RNA-RNA structure and interaction prediction tools. Briefings in Bioinformatics, 25. https://doi.org/10.1093/bib/bbad421
  5. Zabidi, N. A. N., Baharudin, R., Bakarurraini, N. Q. R., Shahri, N. A. A. M., Fu, F. T. Y., Ismail, I., Zawawi, M. R. A., Law, J. W.-F., Lee, L.-H., & Ab Mutalib, N.-S. (2023). Investigating DNA Methylation of Solute Carrier Genes in Colorectal Cancer: A Comprehensive Analysis Using Microarray and Bioinformatics Tools. Progress In Microbes & Molecular Biology, 6(1). https://doi.org/10.36877/pmmb.a0000393
  6. Nazarie, W. F. W. M., Yusof, A. M., Tieng, F. Y. F., Pakarulrazy, N. F. M., Muhammad, R., Suhaimi, S. N. A., Latar, N. H. M., Saidin, S., Rose, I. M., Lee, L.-H., & Mutalib, N.-S. A. (2022). Differential gene expression analysis of papillary thyroid carcinoma reveals important genes for lymph node metastasis. Progress In Microbes & Molecular Biology, 5(1), Article 1. https://doi.org/10.36877/pmmb.a0000269
  7. Tieng, F. Y. F., Lee, L.-H., & Ab Mutalib, N.-S. (2022). Deciphering Colorectal Cancer Immune Microenvironment Transcriptional Landscape on Single Cell Resolution – a Role for Immunotherapy. Frontiers in Immunology, 13. https://www.frontiersin.org/articles/10.3389/fimmu.2022.959705
  8. Tieng, F. Y. F., Abu, N., Lee, L.-H., & Ab Mutalib, N.-S. (2021). Microsatellite Instability in Colorectal Cancer Liquid Biopsy—Current Updates on Its Potential in Non-Invasive Detection, Prognosis and as a Predictive Marker. Diagnostics, 11(3), Article 3. https://doi.org/10.3390/diagnostics11030544
  9. Tieng, F. Y. F., Abu, N., Nasir, S. N., Lee, L.-H., & Ab Mutalib, N.-S. (2021). Liquid Biopsy-Based Colorectal Cancer Screening via Surface Markers of Circulating Tumor Cells. Diagnostics (Basel, Switzerland), 11(11), 2136. https://doi.org/10.3390/diagnostics11112136
  10. Baharudin, R., Tieng, F. Y. F., Lee, L.-H., & Ab Mutalib, N. S. (2020). Epigenetics of SFRP1: The Dual Roles in Human Cancers. Cancers, 12(2), 445. https://doi.org/10.3390/cancers12020445
  11. Mohamad Yusof, A., Tieng, F. Y. F., Muhammad, R., Abdullah Suhaimi, S. N., Mohamed Rose, I., Saidin, S., Jamal, R., Ismail, I., & Ab Mutalib, N.-S. (2020). In-depth characterization of miRNome in papillary thyroid cancer with BRAF V600E mutation. Progress In Microbes & Molecular Biology, 3(1). https://doi.org/10.36877/pmmb.a0000043
  12. Mohd Yunos, R. I., Ab Mutalib, N. S., Tieng, F. Y. F., Abu, N., & Jamal, R. (2020). Actionable Potentials of Less Frequently Mutated Genes in Colorectal Cancer and Their Roles in Precision Medicine. Biomolecules, 10(3), 476. https://doi.org/10.3390/biom10030476
  13. Tieng, F. Y. F., Abu, N., Sukor, S., Mohd Azman, Z. A., Mahamad Nadzir, N., Lee, L.-H., & Ab Mutalib, N. S. (2020). L1CAM, CA9, KLK6, HPN, and ALDH1A1 as Potential Serum Markers in Primary and Metastatic Colorectal Cancer Screening. Diagnostics, 10(7), Article 7. https://doi.org/10.3390/diagnostics10070444
  14. Tieng, F. Y. F., Baharudin, R., Abu, N., Mohd Yunos, R.-I., Lee, L.-H., & Ab Mutalib, N.-S. (2020). Single Cell Transcriptome in Colorectal Cancer—Current Updates on Its Application in Metastasis, Chemoresistance and the Roles of Circulating Tumor Cells. Frontiers in Pharmacology, 11, 135. https://doi.org/10.3389/fphar.2020.00135
  15. Tieng, F. Y. F., Latifah, S. Y., Md Hashim, N. F., Khaza’ai, H., Ahmat, N., Gopalsamy, B., & Wibowo, A. (2019). Ampelopsin e reduces the invasiveness of the triple negative breast cancer cell line, mda-mb-231. Molecules, 24(14), 2619. https://doi.org/10.3390/molecules24142619
  16. Yusof, A. M., Jamal, R., Saidin, S., Muhammad, R., Suhaimi, S. N. A., Rose, I. M., Nazarie, W. F. W., Fu, F. T. Y., & Mutalib, N.-S. A. (2019). Deep Small RNA Sequencing of BRAF V600E Mutated Papillary Thyroid Carcinoma With Lymph Node Metastasis. Frontiers in Genetics, 10, 941. https://doi.org/10.3389/fgene.2019.00941
Chapter in Books
  1. Abdullah-Zawawi, M.-R., Chan, S. N., Tieng, F. Y. F., Mohamed-Hussein, Z.-A., & Ab Mutalib, N.-S. (2024). Drug Repositioning Using Single-Cell RNA Sequencing in Cancer Research (pp. 1–32). Springer International Publishing. https://doi.org/10.1007/16833_2024_441
  2. Tieng, F. Y. F., Osman, M. S., Abdullah-Zawawi, M.-R., Mohamed-Hussein, Z.-A., Amin, M. C. I. B. M., & Mutalib, N.-S. A. (2024). Molecular Markers in Circulating Tumour Cells: Advancing Clinical Precision (pp. 1–28). Springer International Publishing. https://doi.org/10.1007/16833_2024_414