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CURRICULUM VITAE

DR. FRANCIS TIENG YEW FU
DR. FRANCIS TIENG YEW FU
Senior Lecturer
Department Clinical Oncology
Faculty of Medicine

AREAS OF EXPERTISE


  • SINGLE CELL GENOMES
    Life Sciences, Biological Sciences, Genes And Genomes Biology
  • CANCER CELL BIOLOGY
    Medical And Health Sciences, Health Sciences, Biomedical Sciences

ACADEMIC QUALIFICATION


  • PhD(CANCER), (CANCER)
    Universiti Kebangsaan Malaysia (UKM)
  • M.Sc(MEDICAL BIOTECHNOLOGY), (Medical Biotechnology)
    Universiti Putra Malaysia (UPM)
  • B.Sc(BIOMEDICAL SCIENCES), (Biomedical Science)
    Universiti Putra Malaysia (UPM)

ADMINISTRATIVE DUTIES


  • Task Force Member
    01 Jan 2026 - 01 Mar 2028 (Department)
  • Task Force Member
    08 Jan 2026 - 08 Jan 2028 (National)
  • Course Director of Clinical Oncology in the National Postgraduate Medical Curriculum (NPMC) of Malaysia
    06 Mar 2025 - 05 Mar 2027 (National)
  • Task Force Member
    12 Jan 2025 - 16 Apr 2026 (Department)
  • UM X Curie Masterclass of Cancer Molecular Biology 2025 (invited two international speakers)
    03 Jan 2025 - 14 Feb 2025 (International)
  • Committee Members
    03 Dec 2024 - 03 Dec 2024 (International)

MEMBERSHIPS


  • REVIEW EDITOR IN FRONTIERS IN IMMUNOLOGY (Q1, IF=5.7), EDITORIAL BOARD
    Since 2025 (International)
  • REVIEW EDITOR, EDITORIAL BOARD
    Since 2024 (International)
  • MEMBER OF THE ASSOCIATION FOR SINGLE CELL ANALYSIS (ASCA), MEMBER
    Since 2023 (International)
  • MEMBER OF ASIA PACIFIC MICROBIOME & BIOMEDICAL RESEARCH NETWORK (MAMB), MEMBER
    Since 2022 (International)
  • ASSOCIATE MEMBER OF THE MALAYSIAN ONCOLOGICAL SOCIETY (MOS), MEMBER
    2024 to 2025 (National)

AWARD AND STEWARDSHIP


  • Certificate of Excellent Service
    2026, Universiti Malaya

PUBLICATIONS


Article in Journal
WoS
  1. Tieng, Francis Yew Fu; Lee, Learn-Han; Ab Mutalib, Nurul-Syakima (2025). Single-cell RNA-sequencing of circulating tumour cells: A practical guide to workflow and translational applications, CANCER AND METASTASIS REVIEWS. 44(4). doi:10.1007/s10555-025-10293-z
Scopus
  1. Ting U.H., Abidin M.Z.B., Tieng F.Y.F., Abdullah M.S.B., Omoregie A.I., Ab Razak A.F.B., Salleh M.H.B., Mohamad Basri S.N.B. (2025). Postharvest quality of guava with a novel gum Arabic-beeswax-coconut oil coating under ambient and chilling storage, Journal of the Saudi Society of Agricultural Sciences. 24(3). doi:10.1007/s44447-025-00009-8
Others
  1. Norhisan, N. N., Baharudin, R., Bakarurraini, N. Q. R., Shahri, N. A. A. M., Tieng, F. Y. F., Ismail, I., Abdullah-Zawawi, M.-R., Lee, L.-H., & Mutalib, N. S. A. (2024). Decoding the Methylation Patterns of ABC Transporters in Colorectal Cancer. Progress In Microbes & Molecular Biology, 7(1), Article 1. https://doi.org/10.36877/pmmb.a0000450
  2. Mohd Yunos, R. I., Ab Mutalib, N.-S., Khoo, J., Saidin, S., Ishak, M., Syafruddin, S. E., Tieng, F. Y. F., Md Yusof, N. F., Abd Razak, M. R., Mahamad Nadzir, N., Abu, N., Rose, I. M., Sagap, I., Mazlan, L., & Jamal, R. (2023). Whole genome sequencing of Malaysian colorectal cancer patients reveals specific druggable somatic mutations. Frontiers in Molecular Biosciences, 9. https://www.frontiersin.org/articles/10.3389/fmolb.2022.997747
  3. Tieng, F., Abdullah-Zawawi, M.-R., Shahri, N., Mohamed-Hussein, Z.-A., Lee, L.-H., & Ab Mutalib, N.-S. (2023). A Hitchhiker’s guide to RNA-RNA structure and interaction prediction tools. Briefings in Bioinformatics, 25. https://doi.org/10.1093/bib/bbad421
  4. Zabidi, N. A. N., Baharudin, R., Bakarurraini, N. Q. R., Shahri, N. A. A. M., Fu, F. T. Y., Ismail, I., Zawawi, M. R. A., Law, J. W.-F., Lee, L.-H., & Ab Mutalib, N.-S. (2023). Investigating DNA Methylation of Solute Carrier Genes in Colorectal Cancer: A Comprehensive Analysis Using Microarray and Bioinformatics Tools. Progress In Microbes & Molecular Biology, 6(1). https://doi.org/10.36877/pmmb.a0000393
  5. Nazarie, W. F. W. M., Yusof, A. M., Tieng, F. Y. F., Pakarulrazy, N. F. M., Muhammad, R., Suhaimi, S. N. A., Latar, N. H. M., Saidin, S., Rose, I. M., Lee, L.-H., & Mutalib, N.-S. A. (2022). Differential gene expression analysis of papillary thyroid carcinoma reveals important genes for lymph node metastasis. Progress In Microbes & Molecular Biology, 5(1), Article 1. https://doi.org/10.36877/pmmb.a0000269
  6. Tieng, F. Y. F., Lee, L.-H., & Ab Mutalib, N.-S. (2022). Deciphering Colorectal Cancer Immune Microenvironment Transcriptional Landscape on Single Cell Resolution – a Role for Immunotherapy. Frontiers in Immunology, 13. https://www.frontiersin.org/articles/10.3389/fimmu.2022.959705
  7. Tieng, F. Y. F., Abu, N., Lee, L.-H., & Ab Mutalib, N.-S. (2021). Microsatellite Instability in Colorectal Cancer Liquid Biopsy—Current Updates on Its Potential in Non-Invasive Detection, Prognosis and as a Predictive Marker. Diagnostics, 11(3), Article 3. https://doi.org/10.3390/diagnostics11030544
  8. Tieng, F. Y. F., Abu, N., Nasir, S. N., Lee, L.-H., & Ab Mutalib, N.-S. (2021). Liquid Biopsy-Based Colorectal Cancer Screening via Surface Markers of Circulating Tumor Cells. Diagnostics (Basel, Switzerland), 11(11), 2136. https://doi.org/10.3390/diagnostics11112136
  9. Baharudin, R., Tieng, F. Y. F., Lee, L.-H., & Ab Mutalib, N. S. (2020). Epigenetics of SFRP1: The Dual Roles in Human Cancers. Cancers, 12(2), 445. https://doi.org/10.3390/cancers12020445
  10. Mohamad Yusof, A., Tieng, F. Y. F., Muhammad, R., Abdullah Suhaimi, S. N., Mohamed Rose, I., Saidin, S., Jamal, R., Ismail, I., & Ab Mutalib, N.-S. (2020). In-depth characterization of miRNome in papillary thyroid cancer with BRAF V600E mutation. Progress In Microbes & Molecular Biology, 3(1). https://doi.org/10.36877/pmmb.a0000043
  11. Mohd Yunos, R. I., Ab Mutalib, N. S., Tieng, F. Y. F., Abu, N., & Jamal, R. (2020). Actionable Potentials of Less Frequently Mutated Genes in Colorectal Cancer and Their Roles in Precision Medicine. Biomolecules, 10(3), 476. https://doi.org/10.3390/biom10030476
  12. Tieng, F. Y. F., Abu, N., Sukor, S., Mohd Azman, Z. A., Mahamad Nadzir, N., Lee, L.-H., & Ab Mutalib, N. S. (2020). L1CAM, CA9, KLK6, HPN, and ALDH1A1 as Potential Serum Markers in Primary and Metastatic Colorectal Cancer Screening. Diagnostics, 10(7), Article 7. https://doi.org/10.3390/diagnostics10070444
  13. Tieng, F. Y. F., Baharudin, R., Abu, N., Mohd Yunos, R.-I., Lee, L.-H., & Ab Mutalib, N.-S. (2020). Single Cell Transcriptome in Colorectal Cancer—Current Updates on Its Application in Metastasis, Chemoresistance and the Roles of Circulating Tumor Cells. Frontiers in Pharmacology, 11, 135. https://doi.org/10.3389/fphar.2020.00135
  14. Tieng, F. Y. F., Latifah, S. Y., Md Hashim, N. F., Khaza’ai, H., Ahmat, N., Gopalsamy, B., & Wibowo, A. (2019). Ampelopsin e reduces the invasiveness of the triple negative breast cancer cell line, mda-mb-231. Molecules, 24(14), 2619. https://doi.org/10.3390/molecules24142619
  15. Yusof, A. M., Jamal, R., Saidin, S., Muhammad, R., Suhaimi, S. N. A., Rose, I. M., Nazarie, W. F. W., Fu, F. T. Y., & Mutalib, N.-S. A. (2019). Deep Small RNA Sequencing of BRAF V600E Mutated Papillary Thyroid Carcinoma With Lymph Node Metastasis. Frontiers in Genetics, 10, 941. https://doi.org/10.3389/fgene.2019.00941
Chapter in Books
  1. Abdullah-Zawawi, M.-R., Chan, S. N., Tieng, F. Y. F., Mohamed-Hussein, Z.-A., & Ab Mutalib, N.-S. (2024). Drug Repositioning Using Single-Cell RNA Sequencing in Cancer Research (pp. 1–32). Springer International Publishing. https://doi.org/10.1007/16833_2024_441
  2. Tieng, F. Y. F., Osman, M. S., Abdullah-Zawawi, M.-R., Mohamed-Hussein, Z.-A., Amin, M. C. I. B. M., & Mutalib, N.-S. A. (2024). Molecular Markers in Circulating Tumour Cells: Advancing Clinical Precision (pp. 1–28). Springer International Publishing. https://doi.org/10.1007/16833_2024_414

RESEARCH PROJECT


National
  1. 2025 - 2028, Fundamental Research Grant Scheme (FRGS)
    Nanomaterial-based Aptasensor For Fundamental Insights Into Circulating Tumour Cell Detection And Cancer Stem Cell Biology ( Principal Investigator(PI))
  2. 2025 - 2026, Government Agency
    Biosensor Tanpa Wayar Dipacu Pembelajaran Mesin Untuk Pengesahan Biopetanda Protein Dalam Diagnosis Kanser Paru-paru ( Co-Researcher)
Private
  1. 2023 - 2026, Private Funding
    Oral Health Status, Betel Quid Chewing Habits, Food Insecurity And Their Associated Factors Among The Indigenous In Rompin, Pahang ( Co-Researcher)
International
  1. 2025 - 2027, International Funding
    Simplifying Single-cell Rna-sequencing Analysis In Circulating Tumour Cell Research: Development Of A User-friendly Web Platform For Non-computational Researchers ( Principal Investigator(PI))
University
  1. 2025 - 2027, Bantuan Khas Penyelidikan (BKP Special)
    Mapping and Rebuilding Colorectal Cancer Tumour Environments to Improve Treatment Response ( Principal Investigator(PI))
  2. 2025 - 2027, Bantuan Khas Penyelidikan (BKP Special)
    Voice2heart: Voice cloning based beat-to-beat assessment with deep ensemble model for early diagnosis of cardiac malfunctions ( Co-Researcher)
  3. 2025 - 2027, Bantuan Khas Penyelidikan (BKP Special)
    Combining cfDNA Fragmentomics and Methylation Signatures for Non-Invasive Detection of Head and Neck Cancer ( Co-Researcher)