Curriculum Vitae

DR. MUHAMMAD FARID NAZER BIN MUHAMMAD FARUQU

Senior Lecturer
  • Department of Pharmacology
    Faculty of Medicine

AREAS OF EXPERTISE

  • NANOBIOLOGICS
    exosome / extracellular vesicle-based nanobiologics
  • THERAPEUTICS
    cancer nanomedicine

ACADEMIC QUALIFICATION

  • PHD (PHARMACEUTICAL SCIENCE), (Pharmaceutical Science)
    King's College, London
  • MSC (BIOCHEMISTRY), (Biochemistry)
    Cambridge University, United Kingdom

ADMINISTRATIVE DUTIES

  • Coordinator
    15 Oct 2021 - 30 Sep 2023 (Department)
  • 15 Oct 2021 - 30 Sep 2023 (Faculty)

MEMBERSHIPS

  • TISSUE ENGINEERING AND REGENERATIVE MEDICINE SOCIETY OF MALAYSIA (TESMA), MEMBER
    2022 to 2022 (National)
  • CONTROLLED RELEASE SOCIETY - MALAYSIA LOCAL CHAPTER, MEMBER
    2021 to 2022 (National)
  • INTERNATIONAL SOCIETY FOR EXTRACELLULAR VESICLES (ISEV), MEMBER
    2019 to 2021 (International)
  • CONTROLLED RELEASE SOCIETY (CRS), MEMBER
    2019 to 2020 (International)

AWARD AND STEWARDSHIP

  • MAKNA Cancer Research Awards
    Majlis Kanser Nasional (MAKNA), 2021 (National)

PUBLICATIONS

Article in Journal
WoS
  1. Khan, Azalea A.; Man, Francis; Faruqu, Farid N.; Kim, Jana; Al-Salemee, Fahad; Carrascal-Minino, Amaia; Volpe, Alessia; Liam-Or, Revadee; Simpson, Paul; Fruhwirth, Gilbert O.; Al-Jamal, Khuloud T.; de Rosales, Rafael T. M. (2022). PET Imaging of Small Extracellular Vesicles via [Zr-89]Zr(oxinate)(4) Direct Radiolabeling, BIOCONJUGATE CHEMISTRY. 33(3), 473-485. doi:10.1021/acs.bioconjchem.1c00597
  2. Beishenaliev, A., Faruqu, F. N., Leo, B. F., Lit, L. C., Loke, Y. L., Chang, C. C., . . . Kiew, L. V. (2021). Facile synthesis of biocompatible sub-5 nm alginate-stabilised gold nanoparticles with sonosensitising properties. Colloids and Surfaces a-Physicochemical and Engineering Aspects, 627, 10. doi: 10.1016/j.colsurfa.2021.127141
  3. Faruqu, Farid N.; Liam-Or, Revadee; Zhou, Shuai; Nip, Rebecca; Al-Jamal, Khuloud T. (2021). Defined serum-free three-dimensional culture of umbilical cord-derived mesenchymal stem cells yields exosomes that promote fibroblast proliferation and migration in vitro, FASEB JOURNAL. 35(1), . doi:10.1096/fj.202001768RR
  4. Giram, Prabhanjan S.; Wang, Julie Tzu-Wen; Walters, Adam A.; Rade, Priyanka P.; Akhtar, Muhammad; Han, Shunping; Faruqu, Farid N.; Abdel-Bar, Hend M.; Garnaik, Baijayantimala; Al-Jamal, Khuloud T. (2021). Green synthesis of methoxy-poly(ethylene glycol)-block-poly(l-lactide-co-glycolide) copolymer using zinc proline as a biocompatible initiator for irinotecan delivery to colon cancer in vivo, BIOMATERIALS SCIENCE. 9(3), 795-806. doi:10.1039/d0bm01421d
  5. Lazaro-Ibanez, Elisa; Faruqu, Farid N.; Saleh, Amer F.; Silva, Andreia M.; Wang, Julie Tzu-Wen; Rak, Janusz; Al-Jamal, Khuloud T.; Dekker, Niek (2021). Selection of Fluorescent, Bioluminescent, and Radioactive Tracers to Accurately Reflect Extracellular Vesicle Biodistribution in Vivo, ACS NANO. 15(2), 3212-3227. doi:10.1021/acsnano.0c09873
  6. Xu, Lizhou; Faruqu, Farid N.; Lim, Yau M.; Lim, Kee Y.; Liam-Or, Revadee; Walters, Adam A.; Lavender, Paul; Fear, David; Wells, Claire M.; Wang, Julie Tzu-Wen; Al-Jamal, Khuloud T. (2021). Exosome-mediated RNAi of PAK4 prolongs survival of pancreatic cancer mouse model after loco-regional treatment, BIOMATERIALS. 264(), . doi:10.1016/j.biomaterials.2020.120369
  7. Managuli, Renuka S.; Wang, Julie Tzu-Wen; Faruqu, Farid Muhammad; Pandey, Abhjieet; Jain, Sanyog; Al-Jamal, Khuloud T.; Mutalik, Srinivas (2020). Surface engineered nanoliposomal platform for selective lymphatic uptake of asenapine maleate: In vitro and in vivo studies, MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS. 109(), . doi:10.1016/j.msec.2019.110620
  8. Taylor, Peter J.; Hagen, Jana; Faruqu, Farid N.; Al-Jamal, Khuloud T.; Quigley, Bonnie; Beeby, Morgan; Selkirk, Murray E.; Sarkies, Peter (2020). Trichinella spiralis secretes abundant unencapsulated small RNAs with potential effects on host gene expression, INTERNATIONAL JOURNAL FOR PARASITOLOGY. 50(9), 697-705. doi:10.1016/j.ijpara.2020.05.008
  9. Tung, Sim Lai; Fanelli, Giorgia; Matthews, Robert Ian; Bazoer, Jordan; Letizia, Marilena; Vizcay-Barrena, Gema; Faruqu, Farid N.; Philippeos, Christina; Hannen, Rosalind; Al-Jamal, Khuloud T.; Lombardi, Giovanna; Smyth, Lesley Ann (2020). Regulatory T Cell Extracellular Vesicles Modify T-Effector Cell Cytokine Production and Protect Against Human Skin Allograft Damage, FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 8(), . doi:10.3389/fcell.2020.00317
  10. Xu, Lizhou; Faruqu, Farid N.; Liam-or, Revadee; Abu Abed, Omar; Li, Danyang; Venner, Kerrie; Errington, Rachel J.; Summers, Huw; Wang, Julie Tzu-Wen; Al-Jamal, Khuloud T. (2020). Design of experiment (DoE)-driven in vitro and in vivo uptake studies of exosomes for pancreatic cancer delivery enabled by copper-free click chemistry-based labelling, JOURNAL OF EXTRACELLULAR VESICLES. 9(1), . doi:10.1080/20013078.2020.1779458
  11. Faruqu, Farid N.; Wang, Julie Tzu-Wen; Xu, Lizhou; McNickle, Luke; Chong, Eden Ming-Yiu; Walters, Adam; Gurney, Mark; Clayton, Aled; Smyth, Lesley A.; Hider, Robert; Sosabowski, Jane; Al-Jamal, Khuloud T. (2019). Membrane Radiolabelling of Exosomes for Comparative Biodistribution Analysis in Immunocompetent and Immunodeficient Mice - A Novel and Universal Approach, THERANOSTICS. 9(6), 1666-1682. doi:10.7150/thno.27891
  12. Managuli, Renuka S.; Wang, Julie T.; Faruqu, Farid N.; Kushwah, Varun; Rauti, Sushil Y.; Shreya, Ajjappla B.; Al-Jamal, Khuloud T.; Jain, Sanyog; Mutalik, Srinivas (2019). Asenapine maleate-loaded nanostructured lipid carriers: optimization and in vitro, ex vivo and in vivo evaluations, NANOMEDICINE. 14(7), 889-910. doi:10.2217/nnm-2018-0289
  13. Sunoqrot, Suhair; Al-Debsi, Tahany; Al-Shalabi, Eveen; Ibrahim, Lina Hasan; Faruqu, Farid Nazer; Walters, Adam; Palgrave, Robert; Al-Jamal, Khuloud T. (2019). Bioinspired Polymerization of Quercetin to Produce a Curcumin-Loaded Nanomedicine with Potent Cytotoxicity and Cancer-Targeting Potential in Vivo, ACS BIOMATERIALS SCIENCE & ENGINEERING. 5(11), 6036-6045. doi:10.1021/acsbiomaterials.9b01240
  14. Faruqu, Farid N.; Xu, Lizhou; Al-Jamal, Khuloud T. (2018). Preparation of Exosomes for siRNA Delivery to Cancer Cells, JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. (142), . doi:10.3791/58814
  15. Suffian, Izzat F. M.; Wang, Julie T. -W.; Faruqu, Farid N.; Benitez, Julio; Nishimura, Yuya; Ogino, Chiaki; Kondo, Akihiko; Al-Jamal, Khuloud T. (2018). Engineering Human Epidermal Growth Receptor 2-Targeting Hepatitis B Virus Core Nanoparticles for siRNA Delivery in Vitro and in Vivo, ACS APPLIED NANO MATERIALS. 1(7), 3269-3282. doi:10.1021/acsanm.8b00480
ESCI
  1. Faruqu, Farid N.; Zhou, Shuai; Sami, Noor; Gheidari, Fatemeh; Lu, Han; Al-Jamal, Khuloud T. (2020). Three-dimensional culture of dental pulp pluripotent-like stem cells (DPPSCs) enhances Nanog expression and provides a serum-free condition for exosome isolation, FASEB BIOADVANCES. 2(7), 419-433. doi:10.1096/fba.2020-00025

RESEARCH PROJECT

National
  1. 2022 - 2024, Others MOHE - Top 100 (IIRG)-FNW
    Elucidation of Surface Proteins from Plasma-derived Exosomes as Novel Candidate Biomarkers for Lung Cancer Early Detection ( Co-Researcher)
Private
  1. 2022 - 2023, Private Funding
    Exosome-mediated Delivery Of Endogenously Loaded Crispr/ Cas9 Ribonucleoprotein (rnp) Complex Targeting Cd73 For Triple Negative Breast Cancer (tnbc) Immunotheraphy ( Principal Investigator(PI))
  2. 2022 - 2022, Private Funding
    Exosome-mediated Delivery Of Endogenously Loaded Crispr/cas9 Ribonucleoprotein (rnp) Complex For Lung Cancer Immunotherapy ( Principal Investigator(PI))

PAPER PRESENTED

INVITED SPEAKER
  1. MTSF Science & Technology Grant Sharing session, MTSF Science & Technology Grant Sharing session, PPGP, UM (University) (18 Feb 2022 - 18 Feb 2022)
  2. Exosomes: Emerging "Star" in Nanomedicine, Breakfast@UMHealth , UMHealth (University) (22 Sep 2021 - 22 Sep 2021)
  3. Exosomes: Nanomedicine's new "influencer", MyCRS Virtual Seminar Series 3/21 & AGM , Controlled Release Society - Malaysia Chapter (MyCRS) (National) (17 Aug 2021 - 17 Aug 2021)
  4. Membrane radiolabelling of exosomes for comparative biodistribution analysis in immunocompetent and immunodeficient mice, EV Imaging Workshop , International Society for Extracellular Vesicles (ISEV)  (International) (19 Mar 2020 - 19 Mar 2020)
ORAL PRESENTER
  1. Three-dimensional culture of dental pulp pluripotent-like stem cells (DPPSC) enhances Nanog expression and provides a serum-free condition for exosome isolation, Controlled Release Society (CRS) Annual Meeting & Exposition, Controlled Release Society (International) (21 Jul 2019 - 21 Jul 2019)
  2. Membrane radiolabelling of exosomes for comparative biodistribution analysis in immunocompetent and immunodeficient mice, UK Extracellular Vesicles (UKEV) Forum, International Society for Extracellular Vesicles (ISEV) (National) (12 Dec 2017 - 12 Dec 2017)
POSTER PRESENTER
  1. In vivo tracking of extracellular vesicles: comparison across nuclear, optical and luminescence approaches, 12th European and Global Clinical Nanomedicine (CLINAM) Summit, European Foundation for Clinical Nanomedicine (International) (02 May 2020 - 04 May 2020)
  2. Three-dimensional culture of dental pulp pluripotent-like stem cells (DPPSC) enhances Nanog expression and provides a serum-free condition for exosome isolation, International Society for Extracellular Vesicles (ISEV) Annual Meeting , International Society for Extracellular Vesicles (ISEV) (International) (24 Apr 2019 - 28 Apr 2019)

ACADEMIC/PROFESSIONAL SERVICES

Evaluation
  1. (2022) Phd Confirmation Defence (Departmental), University, (Internal Assessor)
  2. (2022) Frgs2022 Internal Reviewer (Faculty Level), University, (Reviewer)

SUPERVISION

Postgraduate Student
Master
  1. (2022) EXOSOME-MEDIATED DELIVERY OF ENDOGENOUSLY LOADED CRISPR/CAS9 RIBONUCLEOPROTEIN (RNP) COMPLEX TARGETING CD73 FOR LUNG CANCER IMMUNOTHERAPY, Zher Pin Goh

TEACHING

Bachelor/First Degree
  1. (2021) DIA2006 - Pharmacology
  2. (2021) UMMP - Ummp Stage 1,2 and 3.3
  3. (2020) UMMP - Ummp Stage 1,2 and 3.3

SOCIAL RESPONSIBILITY ACTIVITIES

  • Invited Speaker for Quranic Moments Series by Harmoni Um, (31 Dec 2021 - 31 Dec 2021) (University)