ARTICLE IN ACADEMIC JOURNALS
| NO | DETAILS OF ARTICLE IN ACADEMIC JOURNALS |
|---|---|
| 1. |
Autophagy is deregulated in cancer-associated fibroblasts from oral cancer and is stimulated during the induction of fibroblast senescence by TGF- 1.
2021
Author(s) : Ian Charles Paterson Source :
Scientific Reports
|
| 2. |
Myofibroblast transdifferentiation is associated with changes in cellular and extracellular ves.icle miRNA abundance
2021
Source :
PLOS ONE
|
| 3. |
Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF- B activation and immune escape.
2021
Author(s) : Ian Charles Paterson, Yap Lee Fah Source :
Nature Communications
|
| 4. |
3D Clumps/Extracellular Matrix Complexes of Periodontal Ligament Stem Cells Ameliorate the Attenuating Effects of LPS on Proliferation and Osteogenic Potential.
2021
Source :
JOURNAL OF PERSONALIZED MEDICINE
|
| 5. |
P2Y purinergic receptor signaling in oral squamous cell carcinoma cell lines and its role in proliferation and cisplatin-mediated apoptosis.
2021
Author(s) : Ian Charles Paterson Source :
Sains Malaysiana
|
| 6. |
Establishing a technique for isolation and characterization of human periodontal ligament derived mesenchymal stem cells.
2021
Author(s) : Ian Charles Paterson Source :
SAUDI DENTAL JOURNAL
|
| 7. |
The development of a novel transforming growth factor- (TGF- ) inhibitor that disrupts ligand-receptor interactions.
2020
Author(s) : Ian Charles Paterson Source :
Eur J Med Chem
|
| 8. |
Development of small molecule inhibitors targeting TGF-β ligand and receptor: Structures, mechanism, preclinical studies and clinical usage.
2020
Author(s) : Ian Charles Paterson Source :
European Journal of Medicinal Chemistry
|
| 9. |
Deregulation of lysophosphatidic acid metabolism in oral cancer promotes cell migration via the up-regulation of COX-2.
2020
Author(s) : Chai Wen Lin, Ian Charles Paterson Source :
Peer J
DOI :
10.7717/peerj.10328
|
| 10. |
Profiling lysophosphatidic acid levels in plasma from head and neck cancer patients.
2020
Source :
Peer J
DOI :
10.7717/peerj.9304
|
| 11. |
Monoamine oxidase A is downregulated in EBV-associated nasopharyngeal carcinoma.
2020
Author(s) : Ian Charles Paterson Source :
Scientific Reports
|
| 12. |
Collagen induces a more proliferative, migratory and chemoresistant phenotype in head and neck cancer via DDR1.
2019
Author(s) : Ian Charles Paterson, Anand Ramanathan Source :
Cancers
|
| 13. |
Comprehensive functional profiling of long non-coding RNAs through a novel pan-cancer integration approach and modular analysis of their protein-coding gene association networks.
2019
Author(s) : Wan Zurina Binti Wan Jaafar Source :
BMC GENOMICS
|
| 14. |
Cisplatin-Resistance in Oral Squamous Cell Carcinoma: Regulation by Tumor Cell-Derived Extracellular Vesicles.
2019
Author(s) : Ian Charles Paterson Source :
Cancers
|
| 15. |
In vitro functional evaluation of isolaureline, dicentrine and glaucine enantiomers at 5-HT2 and 1 receptors.
2019
Author(s) : Ian Charles Paterson Source :
chemical biology and drug design
|
| 16. |
Synthesis and evaluation of nuciferine and roemerine enantiomers as 5-HT2 and 1 receptor antagonists.
2018
Author(s) : Ian Charles Paterson Source :
MedChemComm
|
| 17. |
Clinico-pathological features of oropharyngeal squamous cell carcinomas in Malaysia with reference to HPV infection.
2018
Author(s) : Ian Charles Paterson Source :
Infect Agent Cancer
|
| 18. |
The dynamic roles of TGF-β signalling in EBV-associated cancers.
2018
Source :
cancers
|
| 19. |
A miRNA-145/TGF-β1 negative feedback loop regulates the cancer-associated fibroblast phenotype.
2018
Author(s) : Ian Charles Paterson Source :
Carcinogenesis
|
| 20. |
Susceptibility of Human Oral Squamous Cell Carcinoma (OSCC) H103 and H376 cell lines to Retroviral OSKM mediated reprogramming.
2017
Author(s) : Ian Charles Paterson Source :
Peer J
|
| 21. |
Distinct Biological Potential of Streptococcus gordonii and Streptococcus sanguinis Revealed by Comparative Genome Analysis.
2017
Author(s) : Ian Charles Paterson Source :
Scientific Reports
|
| 22. |
Mechanisms of sphingosine 1-phosphate receptor signalling in cancer.
2017
Author(s) : Ian Charles Paterson Source :
Cellular Signalling
|
| 23. |
Fibroblast activation and senescence in oral cancer.
2017
Author(s) : Ian Charles Paterson Source :
journal of Oral Pathology and Medicine
|
| 24. |
Synthesis and biological evaluation of indole core based derivatives with potent antibacterial activity against resistant bacterial pathogens.
2017
Author(s) : Ian Charles Paterson Source :
Journal of Antibiotics
|
| 25. |
Oncogenic S1P signalling in EBV-associated nasopharyngeal carcinoma activates AKT and promotes cell migration through S1P receptor 3.
2017
Author(s) : Ian Charles Paterson Source :
Journal of Pathology
|
| 26. |
Aberrant expression of the S1P regulating enzymes, SPHK1 and SGPL1, contributes to a migratory phenotype in OSCC mediated through S1PR2.
2016
Author(s) : Ian Charles Paterson Source :
Scientific Reports
|
| 27. |
Comparative Genome Analysis of Fusobacterium nucleatum.
2016
Author(s) : Ian Charles Paterson Source :
Genome Biology and Evolution
|
| 28. |
A new complete mitogenome of the critically endangered Chinese pangolin Manis pentadactyla.
2016
Author(s) : Ian Charles Paterson Source :
Conservation Genetics Resources
|
| 29. |
Streptobase: An oral streptococcus mitis group genomic resource and analysis platform.
2016
Author(s) : Ian Charles Paterson Source :
PLoS One
|
| 30. |
A miR-335/COX-2/PTEN axis regulates the secretory phenotype of senescent cancer-associated fibroblasts.
2016
Author(s) : Ian Charles Paterson Source :
Aging
|
| 31. |
Cell cycle arrest and apoptosis induction via modulation of mitochondrial integrity by Bcl-2 family members and caspase-dependence in Dracaena Cinnabari- treated H400 human oral squamous cell carcinoma.
2016
Author(s) : Ian Charles Paterson Source :
Biomed Research International
|
| 32. |
Pangolin genomes and the evolution of mammalian scales and immunity.
2016
Source :
Genome Research
|
| 33. |
PGD: A pangolin genome hub for the research community.
2016
Author(s) : Ian Charles Paterson Source :
Database (Oxford)
|
| 34. |
HOPX functions as a tumour suppressor in head and neck cancer.
2016
Author(s) : Ian Charles Paterson Source :
Scientific Reports
|
| 35. |
Sphingosine 1-phosphate receptor 2 (S1P2) attenuates reactive oxygen species formation and inhibits cell death: implications for otoprotective therapy.
2016
Author(s) : Ian Charles Paterson Source :
Scientific Reports
|
| 36. |
The opposing roles of NOTCH signalling in head and neck cancer.
2015
Source :
Oral Diseases
|
| 37. |
The Influence of Glycerol on the Binding of Methotrexate to Mycobacterium tuberculosis Dihydroflolate Reductase: A Molecular Modeling Study.
2015
Author(s) : Ian Charles Paterson |
| 38. |
(6E,10E) Isopolycerasoidol and (6E,10E) Isopolycerasoidol methyl ester, prenylated benzopyran derivatives from Pseuduvaria monticola induce mitochondrial-mediated apoptosis in human breast adenocarcinoma cells.
2015
Author(s) : Ian Charles Paterson Source :
PLoS One
|
| 39. |
The antineoplastic properties of FTY720: Evidence for the repurposing of fingolimod.
2015
Author(s) : Ian Charles Paterson |
| 40. |
Down-regulation of LPA receptor 5 to aberrant LPA signalling in EBV- associated nasopharyngeal carcinoma.
2015
Author(s) : Ian Charles Paterson Source :
Journal of Pathology
|
| 41. |
Gene expression profiling reveals biological pathways responsible for phenotypic heterogeneity between UK and Sri Lankan oral squamous cell carcinomas.
2015
Author(s) : Ian Charles Paterson Source :
Oral Oncology
|
| 42. |
The identification of novel Mycobacterium tuberculosis DHFR inhibitors and the investigation of their binding preferences by using molecular modelling.
2015
Author(s) : Ian Charles Paterson Source :
Scientific Reports
|
| 43. |
Nickel(II) complex of polyhydroxybenzaldehyde N4- thiosemicarbazone exhibits anti- inflammatory activity by inhibiting NF- B transactivation.
2014
Author(s) : Ian Charles Paterson Source :
Plos One
|
| 44. |
Identification of the PcrA DNA helicase reaction pathway by applying advanced targeted molecular dynamic simulations
2014
Author(s) : Ian Charles Paterson Source :
molecular simulation
|
| 45. |
Investigating the binding preferences of small molecule inhibitors of human protein arginine methyltransferase 1 using molecular modelling.
2014
Author(s) : Ian Charles Paterson Source :
Journal of Molecular Graphics Modelling
|
| 46. |
Fusobacterium nucleatum strain W1481, a possible new subspecies isolated from a periodontal pocket.
2014
Author(s) : Ian Charles Paterson Source :
Genome Announcements
|
| 47. |
Identification of novel small molecule TGF-beta antagonists using structure-based drug design.
2013
Author(s) : Ian Charles Paterson Source :
J Comput Aided Mol Des
|
| 48. |
The study of interactions between DNA and PcrA DNA helicase by using targeted molecular dynamic simulations.
2013
Author(s) : Ian Charles Paterson |
| 49. |
Genome Sequence of Parvimonas micra Strain A293, Isolated from an Abdominal Abscess from a Patient in the United Kingdom.
2013
Author(s) : Ian Charles Paterson Source :
Genome Announcements
|
| 50. |
TGF-beta enhances invasion and metastasis in Ras-
transfected human malignant epidermal
keratinocytes
2012
Author(s) : Ian Charles Paterson Source :
International Journal of Experimental Pathology
|
| 51. |
TGF-beta1 signalling; connecting aberrant inflammation
and colorectal tumorigenesis.
2012
Author(s) : Ian Charles Paterson Source :
Current Pharmaceutical Design
|
| 52. |
Mitochondrial DNA abnormalities in head and neck
cancer are infrequent and lack prognostic utility.
2011
Author(s) : Ian Charles Paterson |
| 53. |
Lysophosphatidic acid (LPA) and calcitrol drive
human
osteoblastogenesis; requirement of albumin-bound
LPA.
2011
Author(s) : Ian Charles Paterson Source :
Prostaglandins & Other Lipid Mediators
|
| 54. |
TGF-beta inhibits metastasis in late stage human
squamous
cell carcinoma of the skin by a mechanism that
does
not involve Id1.
2010
Author(s) : Ian Charles Paterson Source :
Cancer Letters
|
| 55. |
Upregulation of Eps8 in oral squamous cell carcinoma
promotes cell migration and invasion through integrin-
dependent Rac1 activation.
2009
Author(s) : Ian Charles Paterson Source :
Oncogene
|
| 56. |
Investigating the Conformational Preferences of
Transforming Growth Factor-beta isoforms using
Targeted
Molecular Dynamics Simulations.
2009
Author(s) : Ian Charles Paterson Source :
Journal of Chemical Theory and Computation
|
| 57. |
Expression of Ki-67 and p53 in cutaneous free flaps
used to reconstruct soft tissue defects following
resection of oral squamous cell carcinoma.
2007
Author(s) : Ian Charles Paterson Source :
Oral Oncology
|
| 58. |
Spindle assembly checkpoint and centrosome
abnormalities in oral cancer.
2007
Author(s) : Ian Charles Paterson Source :
Cancer Letters
|
| 59. |
Cell death induced by N-(4-hydroxyphenyl)retinamide in
human epidermal keratinocytes is modulated by TGF-beta
and diminishes during the progression of squamous cell
carcinoma.
2006
Author(s) : Ian Charles Paterson Source :
INTERNATIONAL JOURNAL OF CANCER
|
| 60. |
Dysregulated TGF-beta1-induced Smad signalling
occurs as a result of defects in multiple
components of the TGF-beta signalling pathway in
human head and neck carcinoma cell lines.
2006
Author(s) : Ian Charles Paterson Source :
International Journal of Oncology
|
| 61. |
Over-expression of TGF-beta1 in Smad4-deficient
human malignant oral carcinoma cells causes
tumour regression in vivo by mechanisms that
sensitize cells to apoptosis.
2005
Author(s) : Ian Charles Paterson Source :
Journal of Pathology
|
| 62. |
Induction of an epithelial to mesenchymal
transition in human immortal and malignant
keratinocytes by TGF-beta1 involves MAPK, Smad
and AP-1 signalling pathways.
2005
Author(s) : Ian Charles Paterson Source :
Journal of Cellular Biochemistry
|
| 63. |
TGF-beta signal transduction in oro-facial health
and non-malignant disease (part 1).
2004
Author(s) : Ian Charles Paterson Source :
Critical Reviews in Oral Biology
|
| 64. |
Metastatic dissemination of human malignant oral
keratinocyte cell lines following orthotopic
transplantation reflects response to TGF-beta1.
2004
Author(s) : Ian Charles Paterson |
| 65. |
DLC1 is unlikely to be a primary target for deletions
on chromosome 8p22 in head and neck squamous cell
carcinoma.
2004
Author(s) : Ian Charles Paterson Source :
Genes, chromosomes and cancer
|
| 66. |
The role of TGF-beta in epithelial malignancy and
relevance to the pathogenesis of oral cancer
(part 2).
2004
Author(s) : Ian Charles Paterson Source :
Critical Reviews in Oral Biology and Medicine
|
| 67. |
Attenuated type II TGF-beta receptor signalling
in human malignant oral keratinocytes induces a
less differentiated and more aggressive phenotype
that is
associated with metastatic dissemination.
2004
Author(s) : Ian Charles Paterson Source :
INTERNATIONAL JOURNAL OF CANCER
|
| 68. |
Functional significance of MMP-2 and MMP-9 expression
by human malignant oral keratinocyte cell lines.
2003
Author(s) : Ian Charles Paterson |
| 69. |
The presence of multiple regions of homozygous
deletion at the CSMD1 locus in oral squamous cell
carcinoma question the role of CSMD1 in head and neck
carcinogenesis.
2003
Author(s) : Ian Charles Paterson |
| 70. |
TGF-beta1 acts as a tumor suppressor of human
malignant keratinocytes independently of Smad 4
expression and
ligand-induced G1 arrest.
2002
Author(s) : Ian Charles Paterson Source :
Oncogene
|
| 71. |
A review of inherited cancer syndromes and their
relevance to oral squamous cell carcinoma.
2001
Author(s) : Ian Charles Paterson Source :
Oral Oncology
|
| 72. |
Decreased expression of TGF-beta cell surface
receptors during progression of human oral
squamous cell carcinoma.
2001
Author(s) : Ian Charles Paterson |
| 73. |
Expression of a recombinant extracellular domain
of the type-II TGF-beta receptor; utilisation in
a modified ELISA to screen TGF- agonists and
antagonists.
2001
Author(s) : Ian Charles Paterson Source :
Analytical Biochemistry
|
| 74. |
Overexpression of JunB in undifferentiated malignant
rat oral keratinocytes enhances the malignant
phenotype in vitro without altering cellular
differentiation.
2001
Author(s) : Ian Charles Paterson Source :
INTERNATIONAL JOURNAL OF CANCER
|
| 75. |
Endogenous TGF-beta1 inhibits the growth and
metastatic dissemination of rat oral carcinoma cell
lines but enhances local bone resorption.
2000
Author(s) : Ian Charles Paterson |
| 76. |
DNA studies underestimate the major role of CDKN2A
inactivation in oral and oro-pharyngeal squamous cell
carcinomas.
1999
Author(s) : Ian Charles Paterson |
| 77. |
Loss of differentiation of 4NQO-induced malignant oral
rat keratinocytes correlates with metastatic
dissemination and is associated with a reduced
cellular response to TGF-beta1 and an altered receptor
profile.
1999
Author(s) : Ian Charles Paterson |
| 78. |
FGF receptor expression reflects cellular
differentiation in human oral squamous carcinoma cell
lines.
1998
Author(s) : Ian Charles Paterson Source :
Carcinogenesis
|
| 79. |
Early genetic and functional events in the
pathogenesis of oral cancer.
1997
Author(s) : Ian Charles Paterson Source :
Radiation Oncology Investigations
|
| 80. |
of autocrine TGF-beta1 suppresses the growth of
spindle epithelial cells in vitro and in vivo in the
rat 4NQO model of oral carcinogenesis.
1997
Author(s) : Ian Charles Paterson Source :
INTERNATIONAL JOURNAL OF CANCER
|
| 81. |
p53 expression in odontogenic keratocyst epithelium.
1996
Author(s) : Ian Charles Paterson |
| 82. |
Dysregulation of autocrine TGF-beta isoform production
and ligand responses in human tumour-derived and Ha-
ras-transfected keratinocytes and fibroblasts.
1996
Author(s) : Ian Charles Paterson |
| 83. |
Molecular changes in oral cancer may reflect ethnic
origin and aetiology.
1996
Author(s) : Ian Charles Paterson Source :
Oral Oncology
|
| 84. |
TGF-beta isoforms fail to modulate inositol phosphates
and cAMP in normal and tumour-derived human oral
keratinocytes.
1996
Author(s) : Ian Charles Paterson Source :
Biochimica et Biophysica Acta
|
| 85. |
Cloning and sequence-analysis of an intron-containing
domain from a peptide synthetase encoding of the
entomopathogenic fungus Metarhizium anisopliae.
1996
Author(s) : Ian Charles Paterson Source :
Gene
|
| 86. |
Effects of transforming growth factor beta-1 on growth
regulatory genes in tumour-derived human oral
keratinocytes.
1995
Author(s) : Ian Charles Paterson Source :
Brisitsh Journal of Cancer
|
| 87. |
Presence of human papillomavirus sequences in tumour-
derived human oral keratinocytes which express mutant
p53.
1995
Author(s) : Ian Charles Paterson Source :
Oral Oncology
|
| 88. |
Cuticle degrading proteases from insect moulting fluid
and culture filtrates of entomopathogenic fungi.
1995
Author(s) : Ian Charles Paterson Source :
Comparative Biochemistry and Physiology
|
| 89. |
Cloning and characterisation of a gene encoding a
cuticle-degrading protease from the insect pathogenic
fungus Metarhizium anisopliae.
1995
Author(s) : Ian Charles Paterson Source :
Gene
|
| 90. |
Specific induction of a cuticle-degrading protease of
the insect pathogenic fungus Metarhizium anisopliae.
1994
Author(s) : Ian Charles Paterson Source :
Microbiology
|
| 91. |
Paterson IC, Charnley AK, Cooper RM, Clarkson JM.
Partial characterisation of specific inducers of a
cuticle-degrading protease from the entomopathogenic
fungus Metarhizium anisopliae.
1994
Author(s) : Ian Charles Paterson Source :
Microbiology
|
| 92. |
TGF-beta receptor regulation mediates the response to
exogenous ligand but is independent of the degree of
cellular differentiation in human oral keratinocytes.
1994
Author(s) : Ian Charles Paterson Source :
INTERNATIONAL JOURNAL OF CANCER
|
| 93. |
Molecular events including p53 and k-ras alterations
in the in vitro progression of a human colorectal
adenoma cell line to an adenocarcinoma.
1993
Author(s) : Ian Charles Paterson Source :
Oncogene
|
| 94. |
The regulation of production of a fungal trypsin by
Metarhizium anisopliae.
1993
Author(s) : Ian Charles Paterson Source :
FEMS Microbiol Lett
|
PROCEEDING
| NO | DETAILS OF PROCEEDING |
|---|
RESEARCH PROJECT
| GRANT | PROGRESS | STATUS |
|---|---|---|
|
Senescence and Autophagy in Cancer-associated Fibroblasts (CAFs) of Oral Squamous Cell Carcinoma (OSCC)
Researcher(s) : - |
|
end |
|
Targeting Sphingosine Kinases: A Novel Therapy For Oral Cancer
Researcher(s) : Prof. Dr. Yap Lee Fah |
|
end |
|
Programme Title: Oncogenesis Of Head And Neck Cancer: Initiation, Progression And Heterogeneity.Project Title: Mechanisms Of Oral Carcinogenesis: From Homeostasis To Drug Discovery.
|
|
end |
|
Stromal Fibroblasts As Mediators Of Chemoresistance In Oral Carcinoma Cells
Researcher(s) : Prof. Dr. Ivy Chung, Prof. Dr. Yap Lee Fah |
|
end |
RESEARCH COLLABORATOR
| GRANT | PROGRESS | STATUS |
|---|---|---|
|
Investigating Anti-tumor T Cell Responses In Nasopharyngeal Carcinoma To Refine Vaccine-based
Researcher(s) : Prof. Dr. Ian Charles Paterson |
|
end |
|
Anti-proliferative Activity And Mechanism Of Apoptosis Induction Of Ficus Deltoidea On Oral Cancer Cells In Vitro And In Vivo
Researcher(s) : Prof. Dr. Ian Charles Paterson, Aied Mohammed Hamood Saeed |
|
end |
|
Contribution Of Epstein-barr Virus (ebv) To The Gene Expression Programme Of Nasopharyngeal Carcinoma
Researcher(s) : Prof. Dr. Ian Charles Paterson, Prof. Dr. Saiful Anuar Bin Karsani |
|
end |
|
Establishment Of Malaysian Oral Cancer Cell Lines And Apoptosis Induction Of Oral Cancer Cells Response To Damnacanthal And Nordamnacanthal Extract
|
|
end |
|
Comparative Analysis Of Oral Pathogens: Streptococcus Gordonii And Streptococcus Sanguinis
Researcher(s) : Prof. Dr. Ian Charles Paterson, Prof. Dr. Fathilah Binti Abdul Razak, Prof. Dr. Marina Binti Mohd Bakri, Dr. Nicholas Jakubovics |
|
end |
|
Cell Signaling Molecules As Potential Biomakers And Therapeutic Targets For Oscc
|
|
end |
|
The Notch Signalling Pathway And Treatment Resistance In Head And Neck Cancer
Researcher(s) : Prof. Dr. Ian Charles Paterson, Prof. Dr. Rosnah Binti Mohd Zain, Christopher Dawson |
|
end |
|
Antitumor Effect And Apoptosis Induction Of Phyllanthus Amarus And Dracaena Cinnabari On Oral Cancer Cell Lines In Vitro And In Vivo
|
|
end |