Curriculum Vitae

PROF. DR. CHUNG LIP YONG

Honorary Professor
  • Dean Office
    Faculty of Pharmacy
  • +603-79674971

AREAS OF EXPERTISE


  • MEDICINAL CHEMISTRY
    Medicinal and biomolecular chemistry, CNS active compounds, GPCR modulation, Enzyme inhibition, Targeted drug delivery, Photosensitisers

ACADEMIC QUALIFICATION


  • PhD(1990) (UK), (Lain-Lain)
    University of Wales, Cardiff, UK
  • MSc(1987) (UK), (Science)
    University of Wales, Institute of Sci. & Technical
  • BPHARM(1984) (UK), (Farmasi)
    Bath University, Bath, UK

MEMBERSHIPS


  • UCSI, MSC IN PHARMACEUTICAL CHEMISTRY: BOARD OF STUDIES, BOARD MEMBER
    2018 to 2018 (University)

AWARD AND STEWARDSHIP


  • Top 2% Scientists in the World. Subject field: Medicinal and Biomolecular Chemistry
    Source: Loannidis JPA, Boyack KW, Baas J. (2020). Updated science wide author databases of standardized citation indicators. Plos Biol. 18: e3000918., 2020 (International)
  • 24th Biological Sciences Graduate Congress (Congress), Kuala Lumpur. (Awarded the 1st Runner up for Oral; Applied Science & Biotechnology; Kwa Yee Chu)
    24th Biological Sciences Graduate Congress (Congress), 2019 (National)
  • 1st Malaysian Association for Cancer Research (MACR) Scientific Conference, MAHSA University, Selangor, Malaysia. 3rd-4th December 2019. Best Poster Award (2nd Prize) (Yee Chu Kwa)
    1st Malaysian Association for Cancer Research (MACR) Scientific Conference, 2019 (National)
  • 4th International Pharmaceutical Research Conference "Challenging the Inquisitive Minds: Frontier of the Future". Kuala Lumpur, 25-26 August 2018. - 1st Runner Up (Poster Presentation) (Theebaa A/P Anasamy)
    4th International Pharmaceutical Research Conference, 2018 (National)
  • TienTe Lee Biomedical Foundation - YSPSAH Excellent Scientific Paper Award 2018 (Cheah Hoay Yan)
    TienTe Lee Biomedical Foundation, Taiwan, 2018 (International)
  • Eric Saw Wen Shang. Completion of AKEPT Young Scholars Programme 2016/2017
    Higher Education Leadership Academy (AKEPT), Ministry of Higher Education, 2017 (National)
  • Poster Prize Winner (W S Saw). Size Dependent Cellular Internalization of Confeito-like Gold Nanoparticles in MDA-MB-231 Breast Cancer Cells. W.S. Saw, M. Ujihara, T. Imae, L.V. Kiew, L.Y. Chung. CRS-CooRE-Net Industry-Academia Networking Day (Seminar). Controlled Release Society (CRS), Biopolis, Singapore. 23 June 2017.
    CRS-CooRE-Net Industry-Academia Networking Day (Seminar), Controlled Release Society (CRS), Singapore, 2017 (International)
  • Best Poster Award (P Sahoo). Development and optimization of pH responsive carboxymethylated iota-carrageenan/chitosan nanoparticles for oral insulin delivery. Pratyusa Sahoo, Kok Hoong Leong, Shaik Nyamathulla, Yoshinori Onuki, Kozo Takayama, Lip Yong Chung. The Malaysia Local Chapter of The Controlled Release Society Inc. (MyCRS): Academia Networking Day. 8 August 2017.
    The Malaysia Local Chapter of The Controlled Release Society Inc. (MyCRS): Academia Networking Day, 2017 (National)
  • TienTe Lee Biomedical Foundation - Excellent Scientific Paper Award 2015 (Kue Chin Siang)
    TienTe Lee Biomedical Foundation, Taiwan, 2016 (International)
  • CERTIFICATE OF EXCELLENT SERVICE
    University of Malaya, 2015 (University)
  • KHIDMAT SETIA 20 AWARD
    , 2015
  • EXCELLENCE SERVICE AWARD
    University of Malaya, 2014 (University)
  • CERTIFICATE OF EXCELLENT SERVICE
    University of Malaya, 2012 (University)
  • EXCELLENCE SERVICE AWARD
    University of Malaya, 2011 (University)
  • CERTIFICATE OF EXCELLENT SERVICE
    University of Malaya, 2009 (University)
  • EXCELLENCE SERVICE AWARD
    University of Malaya, 2007 (University)
  • Gold Medal. Mohamed I Noordin, Chung LY. "Thermostable Suppository Bases from Palm Kernel Oil", IENA 2007, Nurnberg, Germany, 3-11-2007.
    IENA 2007, Nurnberg, Germany, 2007 (International)
  • Gold Medal. Mohamed I Noordin, Chung LY, Daniel Chung WS. "Robust Semi-solid Pharmaceutical Bases from Local Palm Oil Resources", IENA 2007, Nurnberg, Germany, 3-11-2007.
    IENA 2007, Nurnberg, Germany, 2007 (International)
  • CERTIFICATE OF EXCELLENT SERVICE
    University of Malaya, 2006 (University)
  • Gold medal. Mohamed I Noordin, Chung LY, Multipurpose thermostable pharmaceutical, phytoceutical and cosmaceutical excipients from local palm oil resources , The Seoul International Invention Fair 2006, Seoul, Korea, 7-11 December 2006
    The Seoul International Invention Fair 2006, Seoul, Korea, 2006 (International)
  • Product innovation (Medicine) - Gold medal. Noordin MI, Chung LY, Multipurpose thermostable pharmaceutical, phytoceutical and cosmaceutical excipients from local palm oil resources , Malaysia Technology Expo 2006 (MTE 2006). PWTC, Kuala Lumpur. 23-25 February 2006.
    Ministry of Science, Technology and Innovation, Malaysia, 2006 (National)
  • First prize Best poster: Pharmaceutical Technology Kiew LV, Chung LY, Khalifah Sidik, Improved antitumour efficiency of gemcitabine via polymeric conjugation
    MPS Pharmacy Scientific Conference 2006, Kuala Lumpur, Malaysia, 2006 (National)
  • First prize - Best poster: Pharmacology (MW Lo) MW Lo, LY Chung, MR Rais, "Development of a 96-well microplate 5-hydroxytryptamine2 competitive receptor binding assay
    MPS Pharmacy Scientific Conference 2005, Kuala Lumpur, Malaysia, 2005 (National)
  • Product innovation - Bronze medal. Noordin MI, Chung LY, Thermostable suppository bases , Malaysia Technology EXPO 2004. PWTC, Kuala Lumpur
    Ministry of Science, Technology and Innovation, Malaysia, 2004 (National)
  • First prize - Best poster (WK Soo). WK Soo, LY Chung, MR Mustafa, "Optimization of Lipoxygenase Inhibitory Assay for High Throughput Screening
    Seminar on Aromatic & Medicinal Plants 2004. Trend and Future Perspectives, Kuala Lumpur, Malaysia, 2004 (National)
  • Bronze - Oral presentation (KF Yap) KF Yap, LY Chung, MR Mustafa, "Development of Muscarinic Receptor Binding Assay
    4th National Science Fellowship Seminar, Pulau Pinang, Malaysia, 2004 (National)
  • EXCELLENCE SERVICE AWARD
    University of Malaya, 2003 (University)
  • First prize - Oral presentation (PY Chung) PY Chung, LY Chung, YF Ngeow, SH Goh, "Antimicrobial Activities of Some Malaysian Plant Species
    The First Joint Congress of the College of Pathology and Malaysian Institute of Laboratory Sciences, Kuala Lumpur, Malaysia, 2003 (National)

PUBLICATIONS


Article in Journal
WoS
  1. Fong, Stephanie Sally; Foo, Yiing Yee; Saw, Wen Shang; Leo, Bey Fen; Teo, Yin Yin; Chung, Ivy; Goh, Boon Tong; Misran, Misni; Imae, Toyoko; Chang, Chia-Ching; Chung, Lip Yong; Kiew, Lik Voon (2022). p Chitosan-Coated-PLGA Nanoparticles Enhance the Antitumor and Antimigration Activity of Stattic - A STAT3 Dimerization Blocker, INTERNATIONAL JOURNAL OF NANOMEDICINE. 17, 137-150. doi:10.2147/IJN.S337093
  2. Geo, Hui Nee; Murugan, Dharmani Devi; Chik, Zamri; Norazit, Anwar; Foo, Yiing Yee; Leo, Bey Fen; Teo, Yin Yin; Kadir, Sharifah Zamiah Syed Binti Syed Abdul; Chan, Yinghan; Chai, Hann Juang; Medel, Maria; Abdullah, Nor Azizan; Johns, Edward J.; Vicent, Maria J.; Chung, Lip Yong; Kiew, Lik Voon (2022). Renal Nano-drug delivery for acute kidney Injury: Current status and future perspectives, JOURNAL OF CONTROLLED RELEASE. 343, 237-254. doi:10.1016/j.jconrel.2022.01.033
  3. Lai, Phei San; Usama, Syed Muhammad; Kiew, Lik-Voon; Lee, Hong Boon; Chung, Lip Yong; Burgess, Kevin; Kue, Chin Siang (2022). Antibody-dependent cellular phagocytosis of tropomyosin receptor kinase C (TrkC) expressing cancer cells for targeted immunotherapy, CANCER IMMUNOLOGY IMMUNOTHERAPY. . doi:10.1007/s00262-022-03147-y
  4. Ng, Yin Zhuang; Tan, Kong Wai; Chung, Lip Yong; Salim, Fatimah; Low, May Lee; Ooi, Ing Hong; Yip, Foo Win; Ng, Chew Hee (2022). Zinc(II)-Schiff base complex functionalized on gold nanospheres: synthesis, characterization, anticancer study and interaction with proteins, JOURNAL OF COORDINATION CHEMISTRY. 75(9-10), 1303-1324. doi:10.1080/00958972.2022.2097869
  5. Saw, Wen Shang; Anasamy, Theebaa; Thu Thi Anh Do; Lee, Hong Boon; Chee, Chin Fei; Isci, Umit; Misran, Misni; Dumoulin, Fabienne; Chong, Wu Yi; Kiew, Lik Voon; Imae, Toyoko; Chung, Lip Yong (2022). Nanoscaled PAMAM Dendrimer Spacer Improved the Photothermal-Photodynamic Treatment Efficiency of Photosensitizer-Decorated Confeito-Like Gold Nanoparticles for Cancer Therapy, MACROMOLECULAR BIOSCIENCE. . doi:10.1002/mabi.202200130
  6. Anasamy, T., Chee, C. F., Wong, Y. E. F., Heh, C. H., Kiew, L. V., Lee, H. B., & Chung, L. Y. (2021). Triorganotin complexes in cancer chemotherapy: Mechanistic insights and future perspectives. Applied Organometallic Chemistry, 35(2), 33. doi: 10.1002/aoc.6089
  7. Beishenaliev, A., Faruqu, F. N., Leo, B. F., Lit, L. C., Loke, Y. L., Chang, C. C., . . . Kiew, L. V. (2021). Facile synthesis of biocompatible sub-5 nm alginate-stabilised gold nanoparticles with sonosensitising properties. Colloids and Surfaces a-Physicochemical and Engineering Aspects, 627, 10. doi: 10.1016/j.colsurfa.2021.127141
  8. Kiew, L. V., Chang, C. Y., Huang, S. Y., Wang, P. W., Heh, C. H., Liu, C. T., . . . Chang, C. C. (2021). Development of flexible electrochemical impedance spectroscopy-based biosensing platform for rapid screening of SARS-CoV-2 inhibitors. Biosensors & Bioelectronics, 183, 10. doi: 10.1016/j.bios.2021.113213
  9. Anasamy, T., Chee, C. F., Kiew, L. V., Chung, L. Y. (2020). In vivo antitumour properties of tribenzyltin carboxylates in a 4T1 murine metastatic mammary tumour model: Enhanced efficacy by PLGA nanoparticles. European Journal of Pharmaceutical Sciences, 142, 9. doi: 10.1016/j.ejps.2019.105140
  10. Ng, S. Y., Kamkaew, A., Fu, N. Y., Kue, C. S., Chung, L. Y., Kiew, L. V., . . . Lee, H. B. (2020). Active targeted ligand-aza-BODIPY conjugate for near-infrared photodynamic therapy in melanoma. International Journal of Pharmaceutics, 579, 14. doi: 10.1016/j.ijpharm.2020.119189
Others
  1. Fong, S.S., Foo, Y.Y., Saw, W.S., Leo, B.F., Teo, Y.Y., Chung, I., Goh, B.T., Misran, M., Imae, T., Chang, C-C., Chung, L.Y., Kiew, L.V. (2022). Chitosan-coated-PLGA nanoparticles enhance the antitumor and antimigration activity of Stattic - A STAT3 dimerization blocker, International Journal of Nanomedicine. 17, 137-150.
  2. Saw, W. S., Anasamy, T., Foo, Y. Y., Kwa, Y. C., Kue, C. S., Yeong, C. H., Kiew, L. V., Lee, H. B., Chung, L. Y. (2021). Delivery of nanoconstructs in cancer therapy: Challenges and therapeutic opportunities. Advanced Therapeutics. 4(3): 2000206. DOI: 10.1002/adtp.202000206.
  3. Viswanathan, G., Chung, L. Y., Srinivas, U. (2021). Heterogeneous differentiation of highly proliferative embryonal carcinoma PCC4 cells induced by curcumin: An in vitro study. Nutrition and Cancer, 73(9), 1780-1791. Accepted (13 Aug 2020), Published online (2 Sept 2020). DOI: 10.1080/01635581.2020.1811883
  4. Anasamy, T., Chee, C.F., Kiew, L.V., Chung, L.Y. (2020). In vivo antitumour properties of tribenzyltin carboxylates in a 4T1 murine metastatic mammary tumour model: Enhanced efficacy by PLGA nanoparticles. European Journal of Pharmaceutical Sciences. 142, 105140. DOI: 10.1016/j.ejps.2019.105140 (IF: 3.53, Q1)
  5. Kwa, Y.C., Tan, Y.F., Foo, Y.Y., Leo. B.F., Chung, I., Kiew, L.V., Imae. T., Yusa, S., Chung, L.Y. (2020) Improved delivery and antimetastatic effects of Stattic by self-assembled amphiphilic pendant-dendron copolymer micelles in breast cancer cell lines. Journal of Drug Delivery Science and Technology, 59, 101905. DOI: 10.1016/j.jddst.2020.101905
  6. N.A.A. Hashikin, B.J.J. Abdullah, C.H. Yeong, K.H. Ng, L.Y. Chung. (2020). Production of 153Sm-labelled microparticles and dosimetric studies for potential application in liver radioembolization. Medical Physics International Journal. 8(2), 99-100.
  7. Shie Yin Ng, Anyanee Kamkaew, Nanyan Fu, Chin Siang Kue, Lip Yong Chung, Lik Voon Kiew, Jatuporn Wittayakun, Kevin Burgess, Hong Boon Lee. (2020). Active targeted ligand-aza-bodipy conjugate for near-infrared photodynamic therapy in melanoma. International Journal of Pharmaceutics. 579, 119189. Doi: 10.1016/j.ijpharm.2020.119189
  8. Hui Li Heng, Chin Fei Chee, Chun Keng Thy, Jia Ti Tee, Sek Peng Chin, Deron R. Herr, Michael J. C. Buckle, Ian C. Paterson, Stephen W. Doughty, Noorsaadah Abd. Rahman, Lip Yong Chung. (2018). In vitro functional evaluation of isolaureline, dicentrine and glaucine enantiomers at 5-HT2 and alpha-1 receptors. Chemical Biology & Drug Design. 93(2), 132-138. Doi.org/10.1111/cbdd.13390
  9. Rusdi, N. Afina, Kue, C. S., Yu, K.-X., Lau, B. F., Chung, L. Y., & Kiew, L. V. (2019). Assessment of Potential Anticancer Activity of Brown Seaweed Compounds Using Zebrafish Phenotypic Assay. Natural Product Communications. https://doi.org/10.1177/1934578X19857909
  10. Sahoo, P., Leong, K. H., Nyamathulla, S., Onuki, Y., Takayama, K., Chung, L. Y. (2019). Chitosan complexed carboxymethylated iota-carrageenan oral insulin particles: Stability, permeability and in vivo evaluation. Materials Today Communications. 20, 100557. Doi: 10.1016/j.mtcomm.2019.100557
  11. Chambre, L., Saw, W.S., Ekineker, G., Kiew, L.V., Chong, W.Y., Lee, H.B., Chung, L.Y., Bretonni re, Y., Dumoulin, F., Sanyal, A. (2018) A Surfactant-Free Direct Access to Porphyrin-Crosslinked Nanogels for Photodynamic and Photothermal Therapy. Bioconjugate Chemistry. 29 (12): 4149 4159. DOI: 10.1021/acs.bioconjchem.8b00787 (IF: 4.49, Tier 1)
  12. Cheah, H.Y., Gallon, E., Dumoulin, F., Hoe, S.Z., Japund i - igon, N., Glumac, S., Lee, H.B., Anand, P., Chung, L.Y., Vicent, M.J., Kiew, L.V. (2018) Near-infrared activatable phthalocyanine-poly-L-glutamic acid conjugate: enhanced in vivo safety and antitumor efficacy towards an effective photodynamic cancer therapy. Molecular Pharmaceutics, 15(7), 2594 2605. DOI: 10.1021/acs.molpharmaceut.8b00132 (IF: 4.44, Tier 1)
  13. Hui Li Heng, Chin Fei Chee, Sek Peng Chin, Yifan Ouyang, Hao Wang, Michael J. C. Buckle, Deron R. Herr, Ian C. Paterson, Stephen W. Doughty, Noorsaadah Abd. Rahman, Lip Yong Chung. (2018). Synthesis and evaluation of nuciferine and roemerine enantiomers as 5-HT2 and 1 receptor antagonists. MedChemComm. 9: 576-582. (MD-RES-12-2017-000629. Accepted (31 January 2018))
  14. Kue, C.S., Ng, S.Y, Voon, S.H., Kamkaew, A., Chung, L.Y., Kiew, L.V., Lee, H.B. (2018) Recent strategies to improve boron dipyrromethene (BODIPY) for photodynamic cancer therapy: An updated review. Photochemical & Photobiological Sciences. 17, 1691-1708. DOI: 10.1039/C8PP00113H (IF: 2.34)
  15. Saw, W. S., Ujihara, M., Chong, W. Y., Voon, S. H., Imae, T., Kiew, L. V., Lee, H. B., Sim, K S., Chung, L. Y. (2018). Size-dependent effect of cystine/citric acid-capped confeito-like gold nanoparticles on cellular uptake and photothermal cancer therapy. Colloids and Surfaces B: Biointerfaces, 161, 365-374. DOI: 10.1016/j.colsurfb.2017.10.064. (IF 3.89, Tier 1)
  16. Siriviriyanun, A., Tsai, Y.J., Voon, S.H., Kiew, S.F., Imae, T., Kiew, L.V., Looi, C.Y., Wong, W.F., Lee, H.B., Chung. L.Y. (2018). Cyclodextrin- and dendrimer-conjugated graphene oxide as a nanocarrier for the delivery of selected chemotherapeutic and photosensitizing agents. Materials Science & Engineering C, 89, 307-315. DOI: https://doi.org/10.1016/j.msec.2018.04.020 (IF 4.164, Tier 2)
  17. Anasamy, T., Thy, C. K., Lo, K. M., Chee, C. F., Yeap, S. K., Kamalidehghan, B., Chung, L. Y. (2017). Tribenzyltin carboxylates as anticancer drug candidates: Effect on the cytotoxicity, motility and invasiveness of breast cancer cell lines. European Journal of Medicinal Chemistry. 125, 770-783. Doi:10.1016/j.ejmech.2016.09.061
  18. Chai, H.J., Kiew, L.V., Chin, Y., Norazit, A., Mohd, Noor. S., Lo, Y.L., Looi, C.Y., Lau, Y.S., Lim, T.M., Wong, W.F., Abdullah, N.A., Abdul Sattar, M.Z., Johns, E.J., Chik, Z., Chung, L.Y. (2017) Renal Targeting Potential of a Polymeric Drug Carrier Poly-L-Glutamic Acid (PG) in Normal and Diabetic Rats. International Journal of Nanomedicine, 2017(12): 577-591, DOI: 10.2147/IJN.S111284 (IF: 4.38, Tier 1)
  19. Cheah, H.Y., Kiew, L.V., Lee, H.B., Japundzic-Zigon, N., Vicent, M.J., Hoe, S.Z., Chung, L.Y. (2017). Preclinical Safety Assessments of Nano-sized-constructs on Cardiovascular System Toxicity: A Case for Telemetry. Journal of Applied Toxicology, 37(11), 1268-1285. DOI: 10.1002/jat.3437 (IF:3.16, Tier 2)
  20. Cheah, H.Y., Sarenac, O., Arroyo, J.J. Vasic, M., Lozic, M., Glumac, S., Hoe, See.Z., Hindmarch, C., Murphy, D., Kiew, L.V., Lee, H.B., Vicent, M.J., Chung, L.Y., Japundzic-Zigon, N. (2017) Hemodynamic effects of HPMA copolymer based doxorubicin conjugate: a randomized controlled and comparative spectral study in conscious rats. Nanotoxicology. 11(2), 210-222. DOI: http://dx.doi.org/10.1080/17435390.2017.1285071 (IF: 7.91, Tier 1)
  21. Hsu, Y.H., Hsieh, H.L., Viswanathan, G., Voon, S.H., Kue, C.S., Saw, W.S., Yeong, C.H., Che Ahmad, A., Imae, T., Kiew, L.V. Lee, H.B., Chung. L.Y. (2017). Multifunctional carbon-coated magnetic sensing graphene oxide-cyclodextrin nanohybrid for potential cancer theranosis. Journal of Nanoparticle Research. 19: 359. doi: 10.1007/s11051-017-4054-9 (IF:2.02, Tier 2).
  22. Kiew, LV., Cheah, HY., Voon, SH., Gallon, E., Movellan, J., Ng, KH., Alpugan, S., Lee, HB., Dumoulin, F., Vicent, MJ., Chung, LY. (2017). Near-Infrared Activatable Phthalocyanine-Poly-L-Glutamic Acid Conjugate: Increased Cellular Uptake and Light Dark Toxicity Ratio Towards An Effective Photodynamic Cancer Therapy. Nanomedicine: Nanotechnology, Biology, and Medicine, 13(4),1447-1458. Doi: 10.1016/j.nano.2017.02.002
  23. Kiew, S. F., Ho, Y. T., Kiew, L. V., Kah, J. C. Y., Lee, H. B., Imae, T., Chung, L. Y. (2017). Preparation and characterization of an amylase-triggered dextrin-linked graphene oxide anticancer drug nanocarrier and its vascular permeability. International Journal of Pharmaceutics, 534(1-2), 297-307, doi: 10.1016/j.ijpharm.2017.10.045 (IF: 3.65, Tier 1)
  24. Mahboubeh Razavi, Hamed Karimian, Chai Hong Yeong, Mehran Fadaeinasab, Si Lay Khaing, Lip Yong Chung, Didi Erwandi B Mohamad Haron, Mohamed Ibrahim Noordin. (2017). Gastroretentive behavior of orally administered radiolabeled tamarind seed formulations in rabbits validated by gamma scintigraphy. Drug Design, Development and Therapy, 10, 1-15. Doi: 10.2147/DDDT.S115466.
  25. Pratyusa Sahoo, Kok Hoong Leong, Shaik Nyamathulla, Yoshinori Onuki, Kozo Takayama, Lip Yong Chung. (2017). Optimization of pH-responsive carboxymethylated iota-carrageenan/chitosan nanoparticles for oral insulin delivery using response surface methodology. Reactive and Functional Polymers, 119, 145-155. Doi: 10.1016/j.reactfunctpolym.2017.08.014
  26. Voon, S.H., Kue, C.S., Imae, T. Saw, W.S., Lee, H.B., Kiew, L.V., Chung, L.Y., Yusa, S. (2017). Doxorubicin-loaded micelles of amphiphilic diblock copolymer with pendant dendron improve antitumor efficacy: In vitro and in vivo studies. International Journal of Pharmaceutics. 534, 136-143, doi: 10.1016/j.ijpharm.2017.10.023 (IF: 3.65, Tier 1)
  27. Chin Siang KUE, Anyanee KAMKAEW, Kevin BURGESS, Lik Voon KIEW, Lip Yong CHUNG, Hong Boon LEE. 2016. "Small Molecules for Active Targeting in Cancer". Medicinal Research Reviews. 36(3): 494-575. DOI: 10.1002/med.21387.
  28. Chin Siang Kue, Anyanee Kamkaew, Siew Hui Voon, Lik Voon Kiew, Lip Yong Chung, Kevin Burgess & Hong Boon Lee. (2016). Tropomyosin Receptor Kinase C Targeted Delivery of a Peptidomimetic Ligand-Photosensitizer Conjugate Induces Antitumor Immune Responses Following Photodynamic Therapy. Scientific Reports. 6: 37209 (DOI: 10.1038/srep37209).
  29. Geetha Viswanathan, Yu-Hsuan Hsu, Siew Hui Voon, Toyoko Imae, Ampornphan Siriviriyanun, Hong Boon Lee, Lik Voon Kiew, Lip Yong Chung, Shin-ichi Yusa. 2016. "A Comparative Study of Cellular Uptake and Subcellular Localization of Doxorubicin Loaded in Self-Assemblies of Amphiphilic Copolymers with Pendant Dendron by MDA-MB-231 Human Breast Cancer Cells." Macromolecular Bioscience. 16(6): 882-895. DOI: 10.1002/mabi.201500435.
  30. Siaw Fui Kiew, Lik Voon Kiew, Hong Boon Lee, Toyoko Imae, and Lip Yong Chung, "Assessing Biocompatibility of Graphene Oxide-Based Nanocarriers: A Review", Journal of Controlled Release. 2016, 226, 217-228.
  31. Sukumaran, S.D., Chee, C.F., Viswanathan, G., Buckle, M.J.C., Othman, R., Abd. Rahman, N. & Chung, L.Y. 2016. Synthesis, biological evaluation and molecular modelling of 2'-hydroxychalcones as acetylcholinesterase inhibitors. Molecules, 21, 955.
  32. Sumaira Naeem, LV Kiew, LY Chung, Muhammad Aqeel Ashraf, Misni Bin Misran, "Liposomes as amphiphilic carriers: encapsulation and stability aspects". Sains Malaysiana. 2016, 45(1), 71-77.
  33. Sumaira Naeem, LV Kiew, LY Chung, YY Teo, Misni Misran. 2016. Optimization of Parameters for Phospholipid Nanoparticle Formulations using Response Surface Methodology. Journal of Surfactant and Detergents. 19(1): 67-74. DOI: 10.1007/s11743-015-1757-8.
  34. SumairaNaeem, Lik Voon Kiew, Lip Yong Chung, Geetha Viswanathan and Misni Bin Misran. (2016). Novel amphiphilic carriers: One step further in cancer management. Journal of Pharmacology & Clinical Research, 1(3), 555561. DOI: 10.19080/JPCR.2016.01.555561.
  35. Topkaya, D., NG, S.Y., Lafont, B.D., Chung, L.Y., Lee, H.B., Dumoulin, F. (2016). Iodination improves the phototoxicity of an amphiphilic porphyrin. Photodiagnosis and Photodynamic Therapy. 16: 12-14. Doi: 10.1016/j.pdpdt.2016.07.008.
  36. Voon SH, Tiew SX, Kue CS, Lee HB, Kiew LK, Misni Misran, Kamkaew A, Burgess K, Chung LY. "Chitosan- coated poly(lactic-co-glycolic acid)-diiodinated boron-dipyrromethene nanoparticles improve tumor selectivity and stealth properties in photodynamic cancer therapy". Journal of Biomedical Nanotechnology. 2016 (Accepted 10 Jan 2016; Manuscript No. 15-1235-R)
  37. Ali Kadivar, Behnam Kamalidehghan, Hamid Akbari Javar, Ehsan Taghizadeh Davoudi, Nurul Dhania Zaharuddin, Bahareh Sabeti, Lip Yong Chung, Mohamed Ibrahim Noordin, Formulation, in vitro evaluation and in vivo gastroretentive study of effervescent floating sustained-release Imatinib mesylate tablet . PlosOne, 2015, 10(6), e0126874 (23 pages) (doi: 10.1371/journal.pone.0126874) (EMID: f5414e708168fa79).
  38. Ampornphan Siriviriyanun, Marina Popova, Toyoko Imae, Lik Voon Kiew, Chung Yeng Looi, Won Fen Wong, Hong Boon Lee, Lip Yong Chung. "Preparation of graphene oxide/dendrimer hybrid carriers for delivery of doxorubicin". Chemical Engineering Journal. 2015, 281, 771-781. (doi: 10.1016/j.cej.2015.07.024)
  39. Chin Siang Kue, Anyanee Kamkaew, Hong Boon Lee, Lip Yong Chung, Lik Voon Kiew, Kevin Burgess, Targeted PDT agent eradicates TrkC expressing tumors via photodynamic therapy (PDT) , Molecular Pharmaceutics. 2015, 12, 212-222 (doi: 10.1021/mp5005564).
  40. Fatemeh Ahmadipour, Mohamed Ibrahim Noordin, Syam Mohan, Aditya Arya, Mohammadjavad Paydar, Chung Yeng Looi, Yeap Swee Keong, Ebrahimi Nigjeh Siyamak, Somayeh Fani, Maryam Firoozi, Lip Yong Chung, Mohamed Aspollah Sukari, Behnam Kamalidehghan, Koenimbin, a natural dietary compound of Murraya koenigii (L) Spreng: inhibition of MCF7 breast cancer cells and targeting of derived MCF7 breast cancer stem cells (CD44+/CD24- /low): an in vitro study . Drug Design, Development and Therapy, 2015, 9, 1193-1208.
  41. M Razavi, H Karimian, CH Yeong, A Ahmad Sarji, LY Chung, S Nyamathulla, M I Noordin, Gamma scintigraphic study of the hydrodynamically balanced matrix tablets of Metformin HCl in rabbits . Drug Design, Development and Therapy, 2015, 9, 3125-3139.
  42. Mahboubeh Razavi, Hamed Karimian, Chai Hong Yeong, Lip Yong Chung, Shaik Nyamathulla, Mohamed Ibrahim Noordin, "Gamma scintigraphic evaluation of floating gastroretentive tablets of metformin HCl using a combination of three natural polymers in rabbit." Drug Design, Development and Therapy. 2015, 9, 4373-4386.
  43. NAA Hashikin, CH Yeong, BJJ Abdullah, KH Ng, LY Chung, R Dahalan, Alan C Perkins. Neutron Activated Samarium-153 Microparticles for Transarterial Radioembolization of Liver Tumour with Post-Procedure Imaging Capabilities. PloS one 10 (9), e0138106
  44. Nurul Ab Aziz Hashikin, Chai Hong Yeong, Basri Johan Jeet Abdullah, Kwan Hoong Ng, Lip Yong Chung, Rehir Dahalan, Alan C. Perkins, Neutron activated Samarium-153 microparticles for transarterial radioembolizqation of liver tumpour with post- procedure imaging capabilities . Plos One, 2015, 10(9), e0138106.
  45. Seetha Ramasamy, Sek Peng Chin, Sri Devi Sukumaran, Michael James Christopher Buckle, Lik Voon Kiew, Lip Yong Chung, In Silico and In Vitro Analysis of Bacoside A Aglycones and its Derivatives as the Constituents Responsible for the Cognitive Effects of Bacopa monnieri , PlosOne. 2015, 10(5), e0126565 [EMID:9e28f83d3b3263a9].
  46. Sumaira Naeem, LV Kiew, LY Chung, YY Teo, Misni Bin Misran, Drug delivery and innovative pharmaceutical development in mimicking red blood cell membrane . Journal of Surfactant and Detergents, 2015, 31(5), 491-508.
  47. Sumaira Naeem, Misni Bin Misran, LV Kiew, LY Chung, SF Kiew, A comparative approach for preparation and physicochemical characterization of lecithin liposomes using chloroform and non-halogenated solvents . Journal of Surfactant and Detergents, 2015, Doi: 10.1007/s11743-015-1689-3
  48. Chai-Hong Yeong, Kwan-Hoong Ng, Basri Johan Jeet Abdullah, Lip-Yong Chung, Khean-Lee Goh, Alan Christopher Perkins. Internal radiation dosimetry of orally administered radiotracers for the assessment of gastrointestinal motility. Applied Radiation and Isotopes. 2014, 94, 216-220 (doi:10.1016/j.apradiso.2014.08.009).
  49. Lim, Siang Hui; Yam, Mun Li; Lam, May Lynn; Kamarulzaman, Fadzly; Samat, Norazwana; Kiew, Lik Voon; Chung, Lip Yong; Lee, Hong Boon, "Photodynamic characterisation of amino acids conjugated 151- hydroxypurpurin-7-lactone for cancer treatment", Molecular Pharmaceutics, 2014, 11: 3164-3173 [doi: 10.1021/mp500351s].
  50. Meyyammai Swaminathan, Chin Fei Chee, Sek Peng Chin, Michael J. C. Buckle, Noorsaadah Abd. Rahman, Stephen W. Doughty, Lip Yong Chung, Flavonoids with M1 muscarinic acetylcholine receptor binding activity , Molecules, 2014, 19, 8933-8948.
  51. Mohamed Ibrahim Noordin, Chung Lip Yong, Mofat,I, Zainuddin,Z, Aditya Arya, Shaik Nyamathulla, Evaluation of palm oil-based paracetamol suppositories by differential scanning calorimetry ,Tropical Journal of Pharmaceutical Research,Vol. 13, 2014, pg. 23-29.
  52. PY Chung, LY Chung, P Navaratnam. Potential targets by pentacyclic triterpenoids from Callicarpa farinosa against methicillin-resistant and sensitive Staphylococcus aureus , Fitoterapia, Vol. 94, 2014, pg. 48-54.
  53. S Ramasamy, LV Kiew, LY Chung. Inhibition of human cytochrome P450 enzymes by Bacopa monnieri standardized extract and constituents , Molecules, Vol. 19, 2014, pg. 2588-2601.
  54. SH Goh, LY Chung, Diabesity: Focus on insulin regulation rather than dietary fats , Malaysian Oil Science and Technology, 2014, 23(2), 103-113
  55. Siang Hui Lim, Hong Boon Lee, Lik Voon Kiew, Lip Yong Chung, Kevin Burgess, Rosamines Targeting the Cancer Oxidative Phosphorylation Pathway , PlosOne, 2013, Vol. 9, e82934.
  56. Siew Hui Voon, Lik Voon Kiew, Hong Boon Lee, Sing Hui Lim, Mohamd Ibrahim Noordin, Anyanee Kamkaew, Kevin Burgess, Lip Yong Chung, In vivo studies of nanostructure-based photosensitizers for photodynamic cancer therapy, Small, 2014, 10(24), 4993-5013. [EMID:dfb1bee3c36b455b] [doi: 10.1002/smll.201401416] .
  57. Vadieh Ghodsinejad Kalahroudi, Behnam Kamalidehghan, Ahoura Arasteh Kani, Omid Aryani, Mahdi Tondar, Fatemeh Ahmadipour, Lip Yong Chung, Massoud Houshmand, Two novel tyrosinase (TYR) gene mutations with pathogenic impact on oculocutaneous albinism type 1 (OCA1) , PlosOne, 2014, 9: e106656. (doi: 10.1371/journal.pone.0106656) (EMID: a268809809d3aba8).
  58. Y Chin, SH Lim, Y Zorlu, V Ahsen, LV Kiew, LY Chung, F Dumoulin, HB Lee. Improved photodynamic efficacy of Zn (II) phthalocyanines via glycerol substitution , PlosOne, 2014, 9(5), e97894. (doi: 10./1371/journal.pone.0097894)
  59. Chai-Hong Yeong, Basri J.J Abdullah, Kwan-Hoong Ng, Lip-Yong Chung, Khean-Lee Goh, Alan C. Perkins. 2013. Fusion of gamma scintigraphic and magnetic resonance images improves the anatomical delineation of radiotracer for the assessment of gastrointestinal transit. Nuclear Medicine Communications Vol 34 No 7.
  60. Chung PY, Chung LY, Navaratnam P. 2013. Identification, by gene expression profiling analysis, of gene targets in Staphylococcus aureus treated with betulinaldehyde. Research in Microbiology. 164: 319-326.
  61. Chung PY, Chung LY, Navaratnam P. 2013. Transcriptional profiles of the response of methicillin-resistant Staphylococcus aureus to pentacyclic triterpenoids. PLos ONE. 8(2): e56687 (doi:10.1371/journal.pone.0056687)
  62. Kamkaew, A., Lim, S.H., Lee, H.B., Kiew, L.V., Chung, L.Y., Burgess, K. (2013) BODIPY Dyes in Photodynamic Therapy. Chemical Society Reviews, 2013, 42:77-88. DOI: 10.1039/c2cs35216h (IF: 40.44, Tier 1)
  63. Vani Munusamy, Beow Keat Yap, Michael J. C. Buckle, Stephen W. Doughty, Lip Yong Chung. 2013. Structure- based identification of aporphines with selective 5- HT2A receptor binding activity. Chemical Biology & Drug Design. 81: 250-256. (DOI: 10.1111/cbdd.12069)
  64. A Kamkaew, SH Lim, HB Lee, LV Kiew, LY Chung, K Burgess, BODIPY dyes in photodynamic therapy , Chemical Society Reviews, In press (available online), DOI:10.1039/C2CS35216H
  65. CH Yeong, BJJ Abdullah, KH Ng, LY Chung, KL Goh, SA Sarji, AC Perkins, Production and first use of 153Sm Cl3-ion exchange resin capsule formulation for assessing for assessing gastrointestinal motility , Applied Radiation and Isotopes. Vol. 70, 2012, pg. 450-455.
  66. Chai-Hong Yeong, Basri Johan Jeet Abdullah, Kwan-Hoong Ng, Lip-Yong Chung, Khean-Lee Goh, Sazilah Ahmad Sarji, Alan Christopher Perkins. 2012. Production and first use of 153SmCl3-ion exchange resin capsule formulation for assessing gastrointestinal motility. Applied Radaiation and Isotopes 70(3) 450-455
  67. KY Chan, K Mohamad, AJA Ooi, Z Imiyabir, LY Chung, Bioactivity-guided fractionation of the lipoxygenase and cyclooxygenase inhibiting constituents from Chisocheton polyandrous Merr. , Fitoterapia. Vol. 83, 2012, pg. 961- 967. (doi: 10.1016/j.fitote.2012.04.018).
  68. LV Kiew, SK Cheong, E Ramli, K Sidik, TM Lim, LY Chung, Efficacy of a poly-L-glutamic acid-gemcitabine conjugate in tumor-bearing mice, Drug Development Research. Vol. 73, 2012, pg. 120-129. (doi: 10.1002/ddr.21012).
  69. Nura Suleiman Gwaram, Hapipah Mohd Ali, Mahmood Ameen Abdulla, Michael J. C. Buckle, Sri Devi Sukumaran, Lip Yong Chung, Rozana Othman, Abeer A. Alhadi, Wageeh A. Yehye, A. Hamid A. Hadi, Pouya Hassandarvish, Hamid Khaledi, Siddig Ibrahim Abdelwahab, Synthesis, characterization, x-ray crystallography, acetylcholinesterase inhibition and antioxidant activities of some novel ketone derivatives of gallic hydrazide derived Schiff bases , Molecules. . Vol. 17, 2012, pg. 2408-2427.
  70. Yeong, C.H., Abdullah, B.J., Ng, K.H., Chung, L.Y., Goh, K.L., Sarji, S.A., Perkins, A.C (2012). Production and first use of 153SmCl3-ion-exchange resin capsule formulation for assessing gastrointestinal motility. Appl Radiat Isot, 70, 450 - 455.
  71. CH Yeong, BJJ Abdullah, KH Ng, LY Chung, KL Goh, SA Sarji, AC Perkins, Neutron activated 153Sm-ion- exchange resin as a tracer for gastrointestinal scintigraphy, Nucl Med Commun. 2011 Dec;32(12):1256- 1260.
  72. Chung Pooi Yin, Parasakthi Navaratnam, Chung Lip Yong. 2011. Synergistic Antimicrobial Activity between Pentacyclic Triterpenoids and Antibiotics against Staphylococcus aureus Strains. Annals of Clinical Microbiology and Antimicrobials. 10: 25 (6 pages).
  73. K H Leong, L Y Chung, M I Noordin, Y Onuki, M Morishita, K Takayama. 2011. Lectin-functionalized carboxymethylated kappa-carrageenan microparticles for oral insulin delivery. Carbohydrate Polymers. 86: 555- 565.
  74. Leong KH, Chung LY, Noordin MI, Mohamad K, Nishikawa M, Onuki Y, Morishita M, Takayama K. 2011. Carboxymethylation of kappa-carrageenan for intestinal- targeted delivery of bioactive macromolecules. Carbohydrate Polymers. 83: 1507-1515.
  75. Kiew, L.V., Cheong, S.K., Sidik. K., Chung, L.Y. (2010). Improved plasma stability and sustained release profile of gemcitabine via polypeptide conjugation, International Journal of Pharmaceutics. 391: 212-220. DOI: 10.1016/j.ijpharm.2010.03.010 (IF: 4.21, Tier 1)
  76. LY Chung, MW Lo, MR Mustafa, SH Goh, Z Imiyabir, "5-Hydroxytryptamine2A receptor binding activity of compounds from Litsea sessilis", 2009, Phytother Res, 23: 330-334.
  77. LY Chung, WK Soo, KY Chan, MR Mustafa, SH Goh, Z Imiyabir "Lipoxygenase inhibiting activity of some Malaysian plants", 2009, Pharm Biol, 47, 1142-1148.
  78. LY Chung, WK Soo, MR Mustafa, SH Goh, Z Imiyabir, "5-Hydroxytryptamine1A receptor binding activity of bisbenzyltetrahydroisoquinoline alkaloids from Popowia odoardi", 2009, Pharm Biol, 47, 1130-1136.
  79. MI Noordin, LY Chung, "Thermostability and polymorphism of theobroma oil and palm kernel oil as suppository bases", 2009, J Therm Anal Calorim, 95 (3): 891-894.
  80. TZB Sheikh, CL Yong (LY Chung), MS Lian, In vitro antioxidant activity of the hexane and methanolic extract of Sargassum baccularia and Cladophora patentiramea , Journal of Applied Sciences. Vol. 9, 2009, pg. 2490-2493
  81. TZB Sheikh, CL Yong (LY Chung), MS Lian, In vitro antioxidant activity of the hexane and methanolic extract of Sargassum baccularia and Cladophora patentiramea , Journal of Applied Sciences. Vol. 9, 2009, pg. 2490-2493
  82. LY Chung, "Antioxidant profiles of a prepared extract of Chinese herbs for the treatment of atopic eczema", 2008, Phytother Res, 22, 493-499
  83. LY Chung, KF Yap, SH Goh, MR Mustafa, Z Imiyabir, "Muscarinic receptor binding activity of polyoxygenated flavones from Melicope subunifoliolata", 2008, Phytochemistry, 69, 1548-1554
  84. Mohamed Ibrahim Noordin, LY Chung, "Robustness of palm kernel oil blend in suppository preparation using acetaminophen as a model drug", 2007, J Pharm Technol, Vol. 23, pg. 339-343.
  85. Noordin MI, LY Chung, "Palm kernel oil blends as suppository bases in the delivery of aspirin", 2007, JUMMEC, 10, 43-50
  86. LY Chung, "The antioxidant properties of garlic compounds: allyl cysteine, alliin, allicin and allyl disulfide", Journal of Medicinal Food, Vol. 9, no. 2, 2006, pg. 205-213.
  87. LY Chung, "Oxidative stress in mouse skin following application of contact allergenic 5-chloro-2-methyl-4-isothiazolin-3-one and oxazolone", Contact Dermatitis, Vol. 52, no. 3, 2005, pg. 170-171.
  88. LY Chung, KF Yap, MR Mustafa, SH Goh, Z Imiyabir, "Muscarinic receptor activity of some Malaysian plant species", Pharmaceutical Biology, Vol. 43, no. 8, 2005, pg. 672-682.
  89. LY Chung, SH Goh, Z Imiyabir, "Central nervous system receptor activities of some Malaysian plant species", Pharmaceutical Biology, Vol. 43, no. 3, 2005, pg. 280- 288.
  90. MI Noordin, LY Chung, "A rapid micro quantification method for paracetamol in suppositories by differential scanning calorimetry", Drug Development and Industrial Pharmacy, Vol. 30, no. 9, 2004, pg. 925-930.
  91. PY Chung, LY Chung, YF Ngeow, SH Goh, Z Imiyabir, "Antimicrobial activities of Malaysian plant species", Pharmaceutical Biology, Vol. 42, no. 4-5, 2004, pg. 292-300.
  92. LY Chung "Editorial. Pharmacy scientific conference 2001", Malaysian Journal of Pharmacy, Vol. 1, no. 2, 2002, pg. 38.
  93. LY Chung, RJ Schmidt, PF Hamlyn, BF Sagar, AM Andrews, TD Turner, "Biocompatibility of potential wound management products: Hydrogen peroxide generation by fungal chitin/chitosans and their effect on the proliferation of murine L929 fibroblasts in culture", Journal of Biomedical Materials Research, Vol. 39, 1998, pg. 300-307.
  94. LY Chung, RJ Schmidt, PF Hamlyn, BF Sagar, AM Andrews, TD Turner, "Biocompatibility of potential wound management products. Fungal mycelia as a source of chitin/chitosan and their effect on the proliferation of human F1000 fibroblasts in culture", Journal of Biomedical Materials Research, Vol. 28, 1994, pg. 463-469.
  95. LY Chung, RJ Schmidt, AM Andrews, TD Turner, "A study of hydrogen peroxide generation by and antioxidant activity of Granuflex (DuoDERM) Hydrocolloid Granules and some other hydrogel / hydrocolloid wound management materials", British Journal of Dermatology, Vol. 129, 1993, pg. 145-153.
  96. RJ Schmidt, LY Chung, "Mild heat shock therapy of contact allergic reactions", Contact Dermatitis, Vol. 28, 1993, pg. 51-53.
  97. RJ Schmidt, LY Chung, "Perturbation of glutathione status and generation of oxidative stress in mouse skin following application of contact allergenic sesquiterpene lactones and isothiocyanates", Xenobiotica, Vol. 23, 1993, pg. 889-897.
  98. RJ Schmidt, LY Chung, AM Andrews, O Spyratou, TD Turner, "Biocompatibility of wound management products: a study of the effects of various polysaccharides on murine L929 fibroblast proliferation and macrophage respiratory burst", Journal of Pharmacy and Pharmacology, Vol. 45, 1993, pg. 508-513.
  99. RJ Schmidt, LY Chung, AM Andrews, TD Turner, "Toxicity of L-ascorbic acid to L929 fibroblast cultures - relevance to biocompatibility testing of materials for use in wound management", Journal of Biomedical Materials Research, Vol. 27, 1993, pg. 521-530.
  100. RJ Schmidt, LY Chung, TD Turner, "Quantification of hydrogen peroxide generation by Granuflex (DuoDERM) Hydrocolloid Granules and its constituents (gelatin, sodium carboxymethylcellulose, and pectin)", British Journal of Dermatology, Vol. 129, 1993, pg. 154-157.
  101. RJ Schmidt, LY Chung, "Biochemical responses of skin to allergenic and non-allergenic nitrohalobenzenes. Evidence that an NADPH-dependent reductase in skin may act as a prohapten activating enzyme", Archives of Dermatological Research, Vol. 284, 1992, pg. 400-408.
  102. Schmidt, R.J., Chung, L.Y. 1990. Oxidative stress occurs in skin in the pre-immunologic phase of the cell-mediated immune response to allergenic 2,4- dinitrohalobenzenes. Free Radical in Biology & Medicine 9(Suppl. 1): 147.
  103. Schmidt, R.J., Khan, L., Chung, L.Y. 1990. Are free radicals and not quinones the haptenic species derived from urushiols and other contact allergenic mono- and dihydric alkylbenzenes? The significance of NADH, glutathione, and redox cycling in the skin. Archives of Dermatological Research 282: 56-64
Chapter in Books
  1. LY Chung, SH Goh, N Majalap "Activity profiles of Malaysian plant species on some G-protein coupled receptors", 2006, Vol. 15, V.K. Singh, J. N. Govil, Khalil Ahmad, Rajeev Kr. Sharma, eds, Recent Progress in Medicinal Plants, Houston, Studium Press LLC, pg. 291-308.
Article in Proceeding
  1. NAA Hashikin, CH Yeong, BJJ Abdullah, KH Ng, LY Chung, R Dahalan, Alan C Perkins. Samarium-153 Labelled Microparticles For Targeted Radionuclide Therapy Of Liver Tumor. World Congress on Medical Physics and Biomedical Engineering, June 7-12 2015, Toronto, Canada.
  2. Tan Kien Sin, Leong Kok Hoong, Chung Lip Yong, Mohamed Ibrahim Noordin "Optimization Of A Sustained Release And Gastroretentive Formulation For Furosemide Using Mathematical Modeling Method (OTech2)", 2007, pg. 64, Commonwealth Pharmaceutical Association-Malaysian Pharmaceutical Society (CPA-MPS) Scientific Conference 2007, Kuala Lumpur, 1-5 August 2007.
  3. Kiew LV, Chung LY, Khalifah Sidik. Improved antitumour efficiency of gemcitabine via polymeric conjugation (Awarded the First Prize for Poster Section - Pharmaceutical Technology) , 6th MPS Pharmacy Scientific Conference, Kuala Lumpur, Malaysia, 8 - 10 September 2006, pp. 67.
  4. Leong KH, Chung LY, Buckle MJC. Optimizing excipient mixtures by mathematical modelling in formulating a sustained-release theophylline tablet , 6th MPS Pharmacy Scientific Conference, Kuala Lumpur, Malaysia, 8 - 10 September 2006. pp. 39.
  5. MW Lo, LY Chung, MR Rais "Development of a 96-well microplate 5-hydroxytryptamine2 competitive receptor binding assay (First Prize, Poster Section - Pharmacology)", MPS Pharmacy Scientific Conference 2005. Responding to new roles & challenges, Petaling Jaya, Malaysia, 13 October 2005, pg. 52.
  6. PY Chung, LY Chung, YF Ngeow, SH Goh, "Antimicrobial Activities of Some Malaysian Plant Species (Awarded the Best Oral Presentation)", The First Joint Congress of the College of Pathology and Malaysian Institute of Laboratory Sciences, Kuala Lumpur, Malaysia, 11 December 2003.
  7. AK Davey, LY Chung, PJ Nicholls "The response of alveolar macrophages to endotoxin in vitro. (Full paper)", PJ Wakelyn, RR Jacobs, RR Rylander, Proceedings of the Nineteenth Cotton and other Organic Dusts Conference, San Antonio, National Cotton Council, Memphis, 1995, pg. 286-293.
Other Publications
  1. LY Chung, "Feasibilty study of the extraction of carrageenan from Eucheuma cottonii. Tacara Sdn Bhd., Malaysia. (Confidential industrial report)", 1996, pg. 1-26. - Technical Report

RESEARCH INTEREST


  • Screening and design of bioactive molecules of pharmacological interest based on CNS related G- protein coupled receptor interaction and enzyme inhibition from synthetic and natural sources (Alzheimer, flavonoid, aporphine)
  • Natural biopolymers as drug delivery systems (carrageenan, insulin)
  • Skin biochemistry and toxicology, and wound healing cascades (Contact irritant, contact allergen, biopolymer)
  • Targeted and EPR-based delivery of anticancer compounds and photosensitizers (drug delivery, targeted delivery, EPR)

RESEARCH PROJECT


National
  1. 2019 - 2023, Fundamental Research Grant Scheme (FRGS)
    Stimuli Responsive Double-stealth?pre-targeting Strategy To Improve Targeted Anticancer Nano-drug Delivery To Deep Tumour Tissues: Mechanism And Pharmacology ( Co-Researcher)
  2. 2019 - 2023, Fundamental Research Grant Scheme (FRGS)
    Mechanistic Study On The Role Of Hypoxia-inducible Factor Prolyl-hydroxylases In Breast Cancer Tumourigenesis Using Selective Small Molecule Chemical Probes ( Co-Researcher)
  3. 2019 - 2022, Fundamental Research Grant Scheme (FRGS)
    A Mechanistic Study To Identify The Upstream Therapeutic Target Of Tribenzyltin Carboxylates For Improving Cancer Chemotherapy ( Principal Investigator(PI))
  4. 2019 - 2022, Others MOHE - Top 100 (IIRG)-FNW
    Development Of Polyelectrolyte-surface-coated-gold-nanoparticles Against Staphylococcus Aureus Biofilm-associated Infections ( Co-Researcher)
  5. 2020 - 2022, RU Geran
    Point-of Care Rapid Hand Foot and Mouth Disease Detection Device ( Co-Researcher)
  6. 2018 - 2021, RU Geran - Fakulti Program
    Nano-drug-carrier Assisted Targeted Drug Delivery For The Prevention And Attenuation Of Acute Kidney Injury: A Mechanistic Proof-of-concept In Vivo Study ( Co-Researcher)
  7. 2018 - 2021, RU Geran - Fakulti Program
    Single Near Infrared Laser Activatable Photosensitizer-dendrimer-decorated Confeito-like Gold Nanoparticles For Synergistic Photodynamic-photothermal Cancer Theraphy: A Mechanistic Study ( Principal Investigator(PI))
  8. 2019 - 2021, RU Geran
    Development Of Ultrasound-responsive-biostealth-nano-pouch For Effective Delivery And Controlled-release Of Tumour Penetrating Metallic Nanoparticles ( Co-Researcher)
  9. 2019 - 2021, RU Geran
    Formulation And Physico-chemical Studies Of Chemically Modified Arabic Gum Microgel For Drug Delivery ( Co-Researcher)
  10. 2017 - 2020, Fundamental Research Grant Scheme (FRGS)
    Nano-stealthing The Stat3-blocker For Improved Anti-metastatic Activity: Mechanistic And Pharmacological Studies ( Co-Researcher)
  11. 2017 - 2020, Geran Penyelidikan Universiti Malaya (UMRG Programme) - AET (Innovative Technology (ITRC))
    In Vitro And In Vivo Tests On Graphene Oxide- Porous Superparamagnetic Nanoparticles As Contrast Agents In Magnetic Resonance Imaging Under Hyperthermia Conditions ( Co-Researcher)
  12. 2016 - 2019, Postgraduate Research Grant (PPP) - Research
    Evaluation of confeito-like gold nanoparticles conjugated with folate and photosensitizer for cancer treatment (photothermal and photodynamic cancer therapy) ( Principal Investigator(PI))
  13. 2016 - 2019, Postgraduate Research Grant (PPP) - Research
    Evaluation Of Halogenated Tetra(hydroxyphenyl)porphyrins And Trkc Ligand-conjugated Bodipy Photosensitizers For Photodynamic Therapy ( Principal Investigator(PI))
  14. 2017 - 2018, Government Agency
    Reviewing The Current Status Of Drug Discovery And Development In Malaysia ( Co-Researcher)
  15. 2014 - 2017, MOSTI-Science Fund
    Radioembolization Samarium Therapy (rest) For Liver Tumour ( Co-Researcher)
  16. 2014 - 2017, Postgraduate Research Grant (PPP) - Research
    Evaluation Of In Vitro And In Vivo Anticancer Effect Of Compounds Gelsemine And Isomitraphylline On Human Breast Cancer Cell Line, Mcf-7And Mcf-7 Stem/progenitor Cells ( Principal Investigator(PI))
  17. 2012 - 2014, Geran Penyelidikan Universiti Malaya (UMRG) - HTM (Wellness)
    Development of MRI based Quantitative Lung Shunting for Treatment Planning in Y-90 Microsphere Therapy ( Co-Researcher)
  18. 2010 - 2011, Geran Penyelidikan Universiti Malaya (UMRG)
    A STUDY ON THE MECHANISMS OF ACTION FOR THE NOOTROPIC EFFECTS OF THE CONSTITUENTS AND HEPATIC METABOLITES OF BACOPA MONNIERI ( Principal Investigator(PI))
  19. 2009 - 2010, Postgraduate Research Grant (PPP) - Research
    VIRTUAL SCREENING AND BIOLOGICAL ASSAY OF COMPOUND LIBRARIES FOR ANTICHOLINESTERASE ACTIVITY ( Main Supervisor)
  20. 2009 - 2010, Postgraduate Research Grant (PPP) - Research
    CHARACTERIZATION OF DOPAMINE AND SEROTONIN RECEPTOR BINDING ACTIVITY OF APORPHINES ( Main Supervisor)
  21. 2008 - 2009, RU Geran
    OPTIMIZATION AND CHARACTERIZATION OF INSULIN ENCAPSULATION BY A NEW POLYMER, CARBOXYMETHYLATED KAPPA-CARRAGEENAN ( Principal Investigator(PI))
  22. 2006 - 2008, 2
    SELF TARGETTING NOVEL POLYMERIC DRUG DELIVERY SYSTEM FOR CANCER TREATMENT ( Principal Investigator(PI))
  23. 2007 - 2008, 7
    ISOLATION AND IDENTIFICATION LIPOXGENASE ACTIVE COMPOUNDS FROM SELECTED PLANT SPIECES USING HIGH THROUGHPUT BIONOLECULAR SCREENING TECHNIQUES ( Principal Investigator(PI))
  24. 2007 - 2008, Postgraduate Research Grant (PPP) - Research
    MODIFIEDPH-SENSITIVE KAPPACARRAGEENAN IN ORAL DRUG DELIVERY OF PEPTIDE-BASED DRUGS ( Main Supervisor)
  25. 2011 - 2016, High Impact Research (HIR)
    Targeted delivery of anti-neoplastic photoactive compounds and peptides ( Principal Investigator(PI))
  26. 2013 - 2016, High Impact Research (HIR)
    Targeted delivery of cancer chemotherapy pro-drugs. ( Principal Investigator(PI))
  27. 2011 - 2013, Fundamental Research Grant Scheme (FRGS)
    INVESTIGATION OF SM-153 AS A NEW RADIOPHARMACEUTICAL FOR GASTROINTESTINAL TRANSIT STUDY ( Consultant)
  28. 2011 - 2013, Geran Penyelidikan Universiti Malaya (UMRG)
    A study on the mechanisms of action for the nootropic effects of the constituents and hepatic metabolites of Bacopa monnieri. Chung Lip Yong, Kiew Lik Voon, Khalit Mohamad. UMRG RG032/10BIO. 2011 (RM 78,000); 2012 (RM 60,000) ( Principal Investigator(PI))
  29. 2006 - 2009, Fundamental Vot
    Synthesis and investigation of the structure- activity relationships of some muscarinic receptor active flavonoid compounds. Michael Buckle, Chung Lip Yong, Noorsaadah Abd. Rahman ( Consultant)
  30. 2007 - 2009, MOSTI (IRPA)
    Structure-based design and synthesis of muscarinic receptor active compounds as potential therapeutic drugs. Michael Buckle, Chung Lip Yong, Noorsaadah Abd. Rahman ( Consultant)
  31. 2007 - 2009, MOSTI (IRPA)
    Self targetting novel polymeric drug delivery system for cancer treatment ( Principal Investigator(PI))
  32. 2008 - 2009, Postgraduate Research Grant(PPP)
    Oral Drug Delivery in Gastrointestinal System Using Biomedical Imaging ( Co-Researcher)
  33. 2008 - 2009, Short Term Research Fund (Vote F)(PJP)
    DESIGN AND DEVELOPMENT OF GASTROINTESTINAL PHANTOM FOR SCINTIGRAPHIC IMAGING ( Consultant)
  34. 2006 - 2008, Industry
    Novel carrageenan-based biopolymer systems for drug delivery ( Principal Investigator(PI))
  35. 2005 - 2007, Fundamental Vote
    Isolation and identification of 5-hydroxy-tryptamine (5HT) receptor agonist(s) and/or antagonist(s) from Litsea sessilis (Lauraceae) using biomolecular screening techniques ( Principal Investigator(PI))
  36. 2003 - 2005, MOSTI (IRPA)
    Novel Polymeric Drug Delivery for Anticancer Drugs ( Consultant)
  37. 2003 - 2004, Short Term Research Fund (Vote F)(PJP)
    Screening of Malaysian Plants for Antimicrobial Activity and Isolation and Identification of Antimicrobial Compounds from Callicarpa farinosa ( Principal Investigator(PI))
  38. 2000 - 2004, MOSTI (NBD)
    Development and Enhancement of Cloned Receptor-based and Enzyme-based Assays to Screen for Potential Biopharmaceuticals ( Principal Investigator(PI))

PAPER PRESENTED


PLENARY SPEAKER
  1. Tribenzyltin carboxylates as anticancer agents: From molecules to animal models, International Research Conference on Pharmaceutical and Allied Health Sciences (IRCPAS 2020), UCSI University, Kuala Lumpur (International) (07 Mar 2020 - 08 Mar 2020)
INVITED SPEAKER
  1. DRUG DISCOVERY, DEVELOPMENT & DELIVERY, Bridging Translational Cancer Research Forum in conjunction with The World Cancer Day, University of Malaya Cancer Research Institute (UMCRi) (University) (03 Mar 2020 - 03 Mar 2020)
  2. Passive and active targeting, and immunomodulation in photodynamic cancer therapy, UCSI University Public Seminar, Faculty of Pharmacy, UCSI University (University) (21 Oct 2019 - 21 Oct 2019)
  3. Oral insulin delivery system based on chitosan complexed carboxymethylated iota-carrageenan nanoparticles , 2019 International Research Collaboration Discussion Forum / Symposium - National Chiao Tung University, Taiwan, National Chiao Tung University, Taiwan (International) (05 Jun 2019 - 08 Jun 2019)
  4. Active and passive targeting and immunostimulation in photodynamic cancer therapy. L Y Chung, The First Materials Research Society of Thailand International Conference (MRS-THAILAND 2017), Materials Research Society of Thailand (International) (31 Oct 2017 - 03 Nov 2017)
ORAL PRESENTER
  1. Improving the Delivery of Antimetastatic Compound Stattic by Self-Assembled Amphiphilic Pendant-Dendron Copolymers in Breast Cancer Cell Lines. Yee Chu Kwa, Yuen Fen Tan, Bey Fen Leo, Ivy Chung, Lik Voon Kiew, Toyoko Imae, Shin-ichi Yusa, Lip Yong Chung. (Awarded the 1st Runner up for Oral; Applied Science & Biotechnology; Kwa Yee Chu), 24th Biological Sciences Graduate Congress, University of Malaya, National University of Singapore and Chulalangkorn University (National) (19 Dec 2019 - 21 Dec 2019)
  2. Tribenzyltin Carboxylates as Anticancer Agents: Evidence from Inhibition of Cancer Cells Viability, Motility and Invasion In Vitro to Tumour Growth In Vivo. Anasamy T, Chee CF, Chung LY., ASEAN Emerging Researchers Conference 2019, ASEAN Young Scientists Network (International) (09 Dec 2019 - 10 Dec 2019)
  3. L Y Chung, C S Kue, K Anyanee, L V Kiew, H B Lee, K Burgess. Peptidomimetic TrkC ligand as a targeting molecule to improve the efficacy of boron dipyrromethene (BODIPY)to eradicate TrkC expressing tumor in photodynamic therapy. 10th International Symposium on Polymer Therpeutics: From Laboratory to Clinical Practice. Centro de Investigacion Principe Felipe, Valencia, Spain. 19-21 May 2014., 10th International Symposium on Polymer Therpeutics: From Laboratory to Clinical Practice. Centro de Investigacion Principe Felipe, Valencia, Spain. 19-21 May 2014., Centro de Investigacion Principe Felipe, Valencia, Spain. (International) (19 May 2014 - 21 May 2014)
POSTER PRESENTER
  1. Improving the Delivery of Antimetastatic Compound Stattic by Self- Assembled Amphiphilic Pendant-Dendron Copolymers in Breast Cancer Cell Lines. Yee Chu Kwa, Yuen Fen Tan, Bey Fen Leo, Ivy Chung, Lik Voon Kiew, Toyoko Imae, Shin-ichi Yusa, Lip Yong Chung. (Best Poster Award; 2nd Prize; Yee Chu Kwa), 1st Malaysian Association For Cancer Research (MACR) Scientific Conference, Malaysian Association For Cancer Research (MACR) and MAHSA University (National) (03 Dec 2019 - 04 Dec 2019)
  2. The application of multifunctional carbon-coated magnetic sensing graphene oxide-cyclodextrin nanohybrid in cancer theranosis. Saw WS, Hsu Y-H, Hsieh H-L, Yeong CH, Imae T, Kiew LV, Chung LY., International Conference of Layers, Films and Membranes for Green, Environmental and Biomedical Sciences. Taiwan Tech., Taipei, Taiwan 14-16 May 2018., National Taiwan University of Science and Technology (NTUST, Taiwan Tec), Taipei, Taiwan (International) (14 May 2018 - 16 May 2018)
  3. Development and optimization of pH responsive carboxymethylated iota-carrageenan/chitosan nanoparticles for oral insulin delivery. P Sahoo, K H Leong, S Nyamathulla, Y Onuki, K Takayama, L Y Chung, Malaysia Controlled Released Society (MyCRS) Academia Networking Day. A Pre-conference event in conjunction with the 7th Asian Conference on Colloid & Interface Science (ACCIS) 2017, Malaysia Controlled Released Society (MyCRS) (National) (08 Nov 2017 - 08 Nov 2017)
  4. Evaluation of Tri-iodinated Porphyrin for Photodynamic Cancer Therapy. S.Y. Ng, D. Topkaya, Y. Bretonni re, D. Lafont, L.Y. Chung, H.B. Lee & F. Dumoulin, Malaysia Controlled Released Society (MyCRS) Academia Networking Day. A Pre-conference event in conjunction with the 7th Asian Conference on Colloid & Interface Science (ACCIS) 2017, Malaysia Controlled Released Society (MyCRS) (National) (08 Aug 2017 - 08 Aug 2017)
  5. Self-Assemblies of Amphiphilic Diblock Copolymers with Pendant Dendron for Anti-Cancer Drug Delivery. W.S. Saw, S.H. Voon, T. Imae, S-I Yusa, H.B. Lee, L.V. Kiew, L.Y. Chung, Malaysia Controlled Released Society (MyCRS) Academia Networking Day. A Pre-conference event in conjunction with the 7th Asian Conference on Colloid & Interface Science (ACCIS) 2017 (Seminar), Malaysia Controlled Released Society (MyCRS) (National) (08 Aug 2017 - 08 Aug 2017)
  6. POLY-L-GLUTAMIC ACID NANOCARRIER FOR ENHANCED ANTICANCER ACTIVITY OF PHOTODYNAMIC THERAPY IN MURINE BREAST CANCER MODEL. Hoay Yan Cheah, Elena Gallon, Lik Voon Kiew, See Ziau Hoe, Fabienne Dumoulin, Maria J. Vicent, Lip Yong Chung, Malaysia Controlled Released Society (MyCRS) Academia Networking Day. A Pre-conference event in conjunction with the 7th Asian Conference on Colloid & Interface Science (ACCIS) 2017, Malaysia Controlled Released Society (MyCRS) (National) (08 Aug 2017 - 08 Aug 2017)
  7. Size Dependent Cellular Internalization of Confeito-like Gold Nanoparticles in MDA-MB-231 Breast Cancer Cells. W.S. Saw, M. Ujihara, T. Imae, L.V. Kiew, L.Y. Chung, CRS-CooRE-Net Industry-Academia Networking Day, Controlled Release Society (CRS), Singapore (International) (23 Jun 2017 - 23 Jun 2017)
OTHERS
  1. Group discussion on Industrial Pharmacy. The objectives are 1. To identify topics needed for current and future practices, 2. To identify skills (cognitive, psychomotor, affective) required for each of the topic, and 3. To discuss assessment methods for the suggested topics., Pharmacy Education Symposium 2017, Department of Pharmacy, University of Malaya (Deans' Council, Faculties/Schools/Departments of Pharmacy of Malaysia) (National) (21 Aug 2017 - 22 Aug 2017)

ACADEMIC/PROF. SERVICES


Evaluation
  1. (2008) External examiner for MSc thesis, Universiti Putra Malaysia. 2008 , (External Examiner)
  2. (2007) External examiner for MSc thesis, Universiti Kebangsaan Malaysia. 2007 , (External Examiner)

SUPERVISION


Postgraduate Student
PhD/ Doctoral
  1. (2023) ULTRASMALL GOLD NANOPARTICLES WITH DEEP TUMOUR PENETRATION AND SONOSENSITISING PROPERTIES TO IMPROVE SONODYNAMIC THERAPY AGAINST BREAST CANCER, ADILET BEISHENALIEV
  2. (2021) Evaluation of Confeito-like Gold Nanoparticles Loaded with Photosensitiser for Improved Photothermal - Photodynamic Cancer Therapy., SAW WEN SHANG
  3. (2020) Evaluation of Iodinated And Glycosylated Porphyrins, And Ligand-Conjugated Aza-Boron Difluoride Dipyrromethane (Aza-Bodipy) Photosensitizers For Improved Photodynamic Cancer Therapy, NG SHIE YIN
  4. (2019) Novel "Terminal-Targeting" based Nono drug Delivery System to Improve Photodynamic Theraphy against Breast Cancer, ADILET BEISHENALIEV
  5. (2018) TRIBENZYLTIN CARBOXYLATES AS ANTITUMOUR DRUG CANDIDATES: IN VITRO AND IN VIVO STUDIES, THEEBAA ANASAMY
  6. (2018) EVALUATION OF IN VITRO AND IN VIVO ANTICANCER EFFECT OF A NATURAL/SYNTHETIC COMPOUND, THEEBAA ANASAMY
  7. (2018) ORAL INSULIN DELIVERY SYSTEM BASED ON CHITOSAN-COMPLEXED CARBOXYMETHYLATED IOTA-CARRAGEENAN NANOPARTICLES, PRATYUSA SAHOO
  8. (2018) TRIBENZYLTIN CARBOXYLATES AS ANTITUMOUR DRUG CANDIDATES: IN VITRO AND IN VIVO STUDIES, THEEBAA ANASAMY
  9. (2017) Evaluation of a near-infrared light absorbing poly-L-glutamic acid-phthalocyanine conjugate in photodynamic anticancer therapy., Cheah Hoay Yan
  10. (2017) EVALUATION OF A NEAR-INFRARED LIGHT ABSORBING POLY-L-GLUTAMIC ACID-PHTHALOCYANINE CONJUGATE IN PHOTODYNAMIC ANTICANCER THERAPY, CHEAH HOAY YAN
  11. (2017) Characterisation of The Serotonin 5-HT2 and a1 Adrenergic Receptor Activities of Selected Aporphines, HENG HUI LI
  12. (2016) STIMULATION OF HAIR GROWTH USING CONDITIONED MEDIA DERIVED FROM DENTAL PULP STEM CELLS EXPANDED IN SERUM FREE MEDIA, THARINI NAWAMALIE ABEYSINGHE GUNAWARDENA
  13. (2016) Study of Amylase-Triggered Dextrin Linked Graphene Oxide As An Anticancer Drug Nanocarrier., KIEW SIAW FUI
  14. (2015) Evaluation of Halogenated Tetra (Hydroxyphenyl) Porphyrins and TrKC Ligand-Conjugated BOPIDY Photosensitizers for Photodynamic Therapy, Ng Shie Yin
  15. (2015) Evaluation of Confeito-like Gold Nanoparticles Conjugated with Folate and Photosensitizer for Cancer Treatment (Photothermal and Photodynamic Cancer Therapy)., Saw Wen Shang
  16. (2015) PRODUCTION OF 153SM-LABELLED MICROPARTICLES AND DOSIMETRIC STUDIES FOR POTENTIAL APPLICATION IN LIVER RADIOEMBOLIZATION, NURUL HASHIKIN BINTI AB. AZIZ
  17. (2015) Evaluations on Efficacy and Immuno-Stimulatory Properties of Tropomyosin Receptor Kinase C Targeted Peptidomimetic Ligand-Diiodo-Boron Dipyrromethene Hybrids in Photodynamic Anticancer Therapy, KUE CHIN SIANG
  18. (2015) Stealth poly(lactic-co-glycolic acid)-diiodinated boron dipyrromethene nanoparticles for improved anticancer photodynamic therapy, VOON SIEW HUI
  19. (2013) Study of amylase-triggered dextrin linked graphene oxide as an anticancer drug nanocarrier., Kiew Siaw Fui
  20. (2013) Stimulation of hair growth using conditioned media derived from dental pulp stem cells expanded in serum free media., Tharini Nawamalie Abeysinghe Gunawardena
  21. (2013) Production and dosimetric studies of 153Sm-microparticles for radioembolization of liver tumours, Nurul Hashikin Bt Ab. Aziz
  22. (2013) ORAL INSULIN DELIVERY SYSTEM BASED ON CHITOSAN MODIFIED CARBOXYMETHYLATED IOTA-CARRAGEENAN NANOPARTICLES, Pratyusa Sahoo
  23. (2013) Evaluations on efficacy and immuno-stimulatory properties of tropomyosin receptor kinase C targeted peptidomimetic ligand-diiodo-boron dipyrromethene hybrids in photodynamic anticancer therapy., Kue Chin Siang
  24. (2013) Characterisation of the serotonin 5-HT2A receptor and alpha-1 adrenergic receptor activities of selected aporphines., Heng Hui Li
  25. (2011) Stealth poly(lactic-co-glycolic acid)-diiodinated boron dipyrromethene nanoparticles to improve tumour selectivity in photodynamic cancer therapy., Voon Siew Hui
  26. (2010) In silico and in vitro studies of pharmacodynamics, pharmacokinetics and herb-drug interactions of Bacopa monnieri derived bacoside A and its derivatives., Seetha A/P Ramasamy
  27. (2010) Imaging neutron activated Sm-153 oral dose forms in the gastrointestinal tract, Yeong Chai Hong
  28. (2010) Evaluation of boron dipyrromethene (BODIPY)-based photodynamic therapy for cancer treatment and drug delivery, Lim Siang Hui
  29. (2009) Elucidation of the mechanism of antimicrobial activity of pentacyclic triterpenoids on Staphylococcus aureus., Chung Pooi Yin (A0800108)
  30. (2007) Development of a novel polymeric gemcitabine derivative for breast cancer treatment, Kiew Lek Voon
  31. (2007) Carboxymethylated kappa-carrageenan for intestinal-targeted delivery of oral insulin, Leong Kok Hoong
  32. (2004) "DEVELOPMENT OF PALM KERNEL OIL BASED RECTAL DRUG DELIVERY SYSTEMS", MOHAMED IBRAHIM BIN NOORDIN
  33. (2004) "DEVELOPMENT OF PALM KERNEL OIL BASED RECTAL DRUG DELIVERY SYSTEMS", MOHAMED IBRAHIM BIN NOORDIN
  34. (2002) Development of palm kernel oil based rectal drug delivery systems, Mohamed Ibrahim Noordin
Master
  1. (2021) Improving the anti-metastatic efficacies of the STAT3 dimerization blocker Stattic against mammary cancer via chitosan-poly (lactic-co-glycolic acid) nanocarrier-based drug delivery, STEPHANIE SALLY FONG
  2. (2020) IMPROVED ANTI-METASTATIC EFFICACY OF STATTIC THROUGH POLYMERIC MICELLAR AND ALBUMIN-BASED NANO-DELIVERY SYSTEMS: IN VITRO STUDIES, KWA YEE CHU
  3. (2018) Improving the anti-metastatic cancer efficacy of the STAT3 protein dimerisation blockers through the use of micellar nano drug-carriers, Kwa Yee Chu
  4. (2018) EFFECTS OF STAT3 PROTEIN DIMERIZATION BLOCKER, STATTIC LOADED IN STEALTH CHITOSAN-COATED-POLY (LACTO-CO-GLYCOLIC ACID) NANOCARRIER TOWARDS IN VITRO CYTOTOXICITY AND MIGRATION ACTIVITIES 2019/2020(1), STEPHANIE SALLY FONG
  5. (2013) Improved physicochemical properties and photodynamic efficacy of Zn(II) phthalocyanines via glycerol substitution, CHIN YUNNI
  6. (2011) Improved physicochemical properties and photodynamic efficacy of Zn(II) phthalocyanines via glycerol substitution., Chin Yunni
  7. (2010) Virtual screening and biological assay of compound libraries for anticholinesterase activity, Sri Devi Sukumaran
  8. (2010) Molecular modelling and evaluation of the serotonin and dopamine receptor binding activity of aporphines, Vani A/P Munusamy
  9. (2010) Isolation and characterisation of lipoxygenase inhibitory compounds from Chisocheton polyandrus Merr., Chan Kit Yee
  10. (2009) Characterisation of anti-inflammatory profiles of synthesized flavonoids and their precursors, Audrey Ooi Joo Ann
  11. (2008) A study of the anti-inflammatory activities of Callicarpa farinosa Roxb. and its major constituent betulinic acid, Tee Chit Thong
  12. (2007) Isolation and characterisation of 5-hydroxy-tryptamine2A receptor active compound from Litsea sessilis (Lauraceae), Lo Mee Wah
  13. (2007) Evaluation of the M1 muscarinic receptor binding activity of flavonoid compounds, Meyyammai Swaminathan
  14. (2007) Biodistribution of poly-L-glutamic acid-(5-3H)-2'-deoxycytidine in mice bearing mammary tumour, Ernidila Ramli
  15. (2006) ISOLATION AND CHARACTERISATION OF 5-HYDROXYTRPTAMINE2A RECEPTOR ACTIVE COMPOUND FROM LITSEA SESSILIS (LAURACEAE), LO MEE WAH
  16. (2006) Development and application of 96-well micrplate based G-protein coupled receptor binding assays for the screening of local plants for potential cardiovascular activities, Venothini Retnam
  17. (2006) Development and application of 96-well microplate lipoxygenase and 5-HT1A receptor screening assays for bioactive extracts and compounds from Malaysian plants, Soo Wei Kwan
  18. (2003) Isolation and characterisation of compounds with muscarinic receptor activity from Melicope subunifoliolata and Ficus septica, Yap Kim Fah
  19. (2002) Screening of Malaysian plants for antimicrobial activity and isolation and identification of antimicrobial compounds of Callicarpa farinosa, Chung Pooi Yin
Under Graduate Students
  1. (2020) Biodegradable PLGA-based Nanoparticles for the Delivery of Chlorin e6. Lee Mun Yik
  2. (2017) SURFACE CHEMISTRY EFFECT OF GOLD NANOPARTICLES ON CELLULAR UPTAKE BY BREAST CANCER CELLS. WEE YING NI
  3. (2017) SIZE DEPENDENT-EFFECT OF CYSTEINE-CAPPED SPHERE LIKE GOLD NANOPARTICLES ON PHOTOTHERMAL ANTICANCER TREATMENT EFFICACY. LEE SOCK YIN
  4. (2017) SIZE DEPENDENT EFFECT OF CYSTEINE-CAPPED SPHERE LIKE GOLD NANOPARTICLES ON CELLULAR UPTAKE BY BREAST CANCER CELL. CHONG CHIN MAN
  5. (2016) Preparation and characterisation of N,N-diisopropylcarbamothioylsulfanyl acetate ligand-based tribenzyltin derivative poly(lactic-co-glycolic acid) (PLGA) nanoparticles
  6. (2016) Cytotoxicity of tribenzyltin derivatives containing isonicotinate ligand on MDA-MB-231 breast ancer cell line. Lee Ling Wei
  7. (2014) Stability studies on oral insulin nanoparticle complexation between chitosan and carrageenan. Foong Sook Yeng
  8. (2013) Preparation and characterisation of verteporfin loaded polylactic-co-glycolic acid nanoparticles for photodynamic therapy. Kueh Siew Min
  9. (2013) Dendrimer-coated graphene oxide as potential drug carriers. Soong Yit Loo
  10. (2013) A study of the ratio of amino-beta-cyclodextrin to graphene oxide in the preparation of cyclodextrin-graphene oxide hybrid for drug delivery. Jennifer Lee Wei Ting
  11. (2012) Preparation and characterization of zinc phthalocyanine-loaded poly(lactic-co-glycolic acid) nanoparticles for photodynamic therapy. Lee Wan Nee
  12. (2012) Preparation and characterization of boron dipyromethene loaded poly-lactic-co-glycolic acid nanoparticles for photodynamic therapy. Choong Zu Tang
  13. (2012) Effect of Bacopa monniera L. on cholinesterase activity. Ong Wei Yan
  14. (2012) Antioxidant profile of Bacopa monnieri L. Mery Hu Wei Ying
  15. (2012) Antioxidant profile of Bacopa monnieri L. Lim Siow Hoong
  16. (2011) Effect of heterocyclic chalcones on beta-amyloid fibril formation. Lu Man Fai
  17. (2011) Antioxidant profile of Gingko biloba preparations as complementary medicines for Alzheimer's disease. Lin Hui Li
  18. (2011) Antioxidant profile of complementary medicines for Alzheimer's disease. Lau Chin Hwee
  19. (2011) Anticholinesterase activity of some heterocyclic chalcones. Tai Chu Hong
  20. (2010) The effect of Bacopa monniera L. on cholinesterase activity. Khairul Iz'aan Bin Hasnan
  21. (2010) Effect of Bacopa monniera L. on beta-amyloid formation. Thoh Xin Mei
  22. (2010) Antioxidant profiles of Bacopa monniera L. Chua Yi Siang and Nur Nadia Akmal Bt. Abdul Wahid Akmal
  23. (2010) Antioxidant activity of Bacopa monniera L. in biological systems. Tan Chui Theng
  24. (2009) Inhibition activity of flavonoids on phospholipase A2. Yew Shi Fen
  25. (2009) Inhibition activity of flavonoids on lipoxygenase. Wan Nor Azira Bt Wan Abdullah
  26. (2009) Implication of oxidative stress on depression. Chang Chee Tao
  27. (2009) Implication of oxidative stress on anxiety. Teo Liu Chiew
  28. (2009) Implication of oxidative stress in cognition (Alzheimer's disease). Lau Siew Yan
  29. (2007) The use of mathematical modelling to optimise sustained release tablet formulation for ibuprofen. Lee Hui Sim
  30. (2007) The use of mathematical modelling to optimise sustained release tablet formulation for furosemide. Woo Chee Yen
  31. (2007) Inhibition activity of triterpenoids on phospholipase A2. Ketty Ahsoh
  32. (2007) Antioxidant profiles of some Malaysian plants species. Nur Azidah Abdul Aziz & Ker Chin Keong
  33. (2006) Optimization of a sustained release formulation for ibuprofen using mathematical modelling. Yeap Li Ling
  34. (2006) Inhibition activity of betulinic acid and its related compounds on phospholipase A2. Liang Chee Kiong
  35. (2006) Apoptotic activity of betulinic acid and its related compounds. Halimatun Saedah Binti Zulkifli
  36. (2005) Isolation of potential lipoxygenase inhibitors from Malaysian plant species: Garcinia sp. or Gomphia sp. Liyana Roslan
  37. (2005) Isolation of potential cytotoxic compounds from Malaysian plant species: Dendrocnide sp. Yew Koon Wei
  38. (2005) Isolation of potential cytotoxic compounds from Malaysian plant species: Borneodendron sp. Suliyana Bt Yaakob
  39. (2004) Screening of Malaysian plants for alpha adrenergic receptor activities. Nor Aina Kamarudin & Izrul Azwa Mohd Latiff
  40. (2004) Screening for potential lipoxygenase inhibitors from some Malaysian plants. Tan Jye Yee
  41. (2004) Screening for potential lipoxygenase inhibitors from some Malaysian plants. Kong Su Shan
  42. (2004) In vitro biocompatibility studies on peptide polymers as potential chemotherapeutic drug carrier. Tiong Lee Len
  43. (2004) Cytotoxicity screening on some Malaysian Plants. Mok Poi Wan
  44. (2002) Management of hypokalaemia in paediatrics in University Malaya Medical Centre (UMMC). Yip Wai Ling
  45. (2002) Cytotoxicity profiling of some natural products. Lee Li Fung
  46. (2002) Comparative evaluation of simvastatin in the University of Malaya Medical Centre (UMMC). Siti Hajar Bt Hakim
  47. (2002) A review of hormone replacement therapy in postmenopausal women. Phang Kai Ming
  48. (2002) An audit of the therapeutic drug monitoring service for amikacin in UMMC. Tan Bee San
  49. (2000) Physicochemical characteristics of Ginkgo biloba products. Lee Ming Woan
  50. (2000) Isolation and structural elucidation of alkaloids from Actinodaphne montana Gamb. Azliah Sakiman
  51. (1999) Pharmacognostic studies of Centella asiatica. Noor Umaiyah Bt Hassan
  52. (1999) Evaluation of Gingko biloba products in Malaysia market. Nazlina Bt Ahmad
  53. (1999) Antioxidant and pro-oxidant profiles of Morinda citrifolia. Lew Hon Kean
  54. (1998) A study on the antioxidant / pro-oxidant profiles of Hibiscus sabdariffa Linn. Lee Ming Chong
  55. (1998) A study on the antioxidant profiles of tocoperols extract from palm oil. Lau Yee Chiew

TEACHING


Bachelor
  1. (2020) OIA2002 - Pharmaceutical Analysis
  2. (2020) OIA3021 - Pharmaceutical Biotechnology
  3. (2020) OIA4006 - Research Methodology
  4. (2019) MWEF3108 - Pharmaceutical Biotechnology

PATENT/IPR


  • Mohamed Ibrahim Noordin, LY Chung. Thermostable suppository bases, 2005, (06-02-03-0727).
    Patent (National)
  • M Fowler, TR Burrow, TD Turner, RJ Schmidt, LY Chung. Wundverbnde, 2000.
    Patent (International)
  • M Fowler, TR Burrow, TD Turner, RJ Schmidt, LY Chung. Wound dressing, 1997.
    Patent (International)
  • RJ Schmidt, LY Chung. Treatment of allergic contact dermatitis, 1996.
    Patent (International)
  • M Fowler, TR Burrow, TD Turner, RJ Schmidt, LY Chung. Pansements Pour Les Plaies.(Vol. 134, No. 40)
    Patent (International)
  • POLY-L-GLUTAMIC ACID DRUG CARRIER FOR TARGETING AND TREATING KIDNEY DISEASES.
    Patent (National)
  • CYCLODEXTRIN-CONJUGATED GRAPHENE OXIDE AS DRUG NANOCARRIER FOR HIGHLY EFFICIENT LOADING AND DELIVERY OF DOXORUBICIN
    Patent (National)
  • Basri Johan Jeet Abdullah, CH Yeong, LY Chung, KH Ng, Neutron activated 153Sm labelled microspheres, 2012, MyIPO PI 2012 700480.
    Patent
  • LY Chung, LV Kiew, Khalifah Sidik, SK Cheong. Novel polymeric gemcitabine derivative for cancer treatment. (06-02-02-0015-PR 0002/07-05). MY-157802A.
    Patent (National)
  • LY Chung, SF Ngeow, PY Chung. Bioactive fraction from Callicarpa farinosa, 2005.
    Patent (National)