Curriculum Vitae

ASSOCIATE PROF. DR. CHANG LI YEN

Associate Professor
  • Department of Medical Microbiology
    Faculty of Medicine
  • changliyen
  • +603-79675761

AREAS OF EXPERTISE

  • BIORISK MANAGEMENT
    Teaching, research and administration of laboratory biosafety and biosecurity
  • VACCINES
    Development of candidate vaccines
  • EPIDEMIOLOGY
    Epidemiology and mechanism of transmission of emerging and re-emerging infectious diseases
  • VIROLOGY
    Viral pathogenesis and characterization of host cellular responses during virus infection

ACADEMIC QUALIFICATION

  • PHD, (2007) (UM), (Molecular Virology)
    Universiti Malaya (UM)
  • MSc(2002) (UPM), (Biologi Molekul)
    Universiti Putra Malaysia (UPM)
  • BSc(1998) (UPM), (Biotechnology)
    Universiti Putra Malaysia (UPM)

ADMINISTRATIVE DUTIES

  • Head of Department
    09 Jan 2024 - present (Department of Medical Microbiology, Faculty of Medicine)
  • Course Coordinator
    01 Jan 2022 - 31 Dec 2024 (Department)
  • Coordinator
    19 Jan 2022 - 18 Jan 2024 (Department)
  • Committee Members
    05 Oct 2022 - 31 Dec 2023 (National)
  • Coordinator
    27 Jan 2023 - 30 Sep 2023 (Department of Biomedical Science, Faculty of Medicine)
  • Chairperson, Faculty of Medicine Institutional Animal Care and Use Committee
    07 Jul 2020 - 31 Dec 2022 (University Malaya)
  • Committee Members
    01 Jun 2019 - 31 Dec 2022 (University Malaya)
  • Member of Institutional Biosafety and Biosecurity Committee
    08 May 2019 - 07 May 2021 (University Malaya)
  • Ahli J/K Pengubalan Peraturan Kenajikan Haiwan (Penyelidikan, Ujian dan Pengajaran) di bawah Akta Kebajikan Haiwan 2015
    09 Jan 2019 - 31 Dec 2020 (National)
  • Coordinator - Kursus Elektif Luar Fakulti, GIM2003, Pengenalan Kepada Penyakit Berjangkit
    02 Jan 2019 - 19 Dec 2020 (University Malaya)
  • Coordinator - Koordinat r Penyelidikan, Jabatan Mikrobiologi Perubatan, Fakulti Perubatan
    20 Dec 2018 - 19 Dec 2020 (Department of Medical Microbiology, Faculty of Medicine)
  • Resource person - KOBSA-C3BIRD Online Training (Biosafety)
    28 Oct 2020 - 09 Dec 2020 (Dean Office, Faculty of Medicine)
  • Ahli J/K Ijazah Tinggi (JKIT)
    28 Nov 2018 - 27 Nov 2020 (Department of Medical Microbiology, Faculty of Medicine)
  • Chairperson, Faculty of Medicine Institutional Animal Care and Use Committee
    04 Jul 2018 - 03 Jul 2020 (University Malaya)
  • University of Malaya Laboratory Safety Guidelines Writing Team
    11 Aug 2019 - 31 Mar 2020 (University Malaya)
  • Member of Faculty of Medicine, Institutional Animal Care and Use Committee
    01 Jun 2017 - 31 May 2019 (Dean Office, Faculty of Medicine)
  • Assistant Chairperson, Faculty of Medicine Institutional Animal Care and Use Committee
    01 May 2017 - 30 Apr 2019 (University Malaya)
  • Member of Institutional Biosafety and Biosecurity Committee
    01 Apr 2017 - 31 Mar 2019 (University Malaya)
  • Panel Penilai Geran Penyelidikan Perubatan Dato' Dr Mahmood Merican 2018
    20 Sep 2018 - 19 Oct 2018 (Dean Office, Faculty of Medicine)
  • Member of J/K Penilai Geran PPP
    01 Oct 2015 - 30 Sep 2018 (Dean Office, Faculty of Medicine)
  • Panel Penilai Skim FRGS 2018 Peringkat IPPP
    25 May 2018 - 25 Jun 2018 (University Malaya)
  • Deputy Director
    01 Jan 2016 - 01 Mar 2017 (Tropical Infectious Diseases Research & Education Centre (TIDREC), Deputy Vice-Chancellor (Research and Innovation))
  • Member of Faculty of Medicine, Institutional Animal Care and Use Committee
    01 Jun 2015 - 31 May 2017 (Dean Office, Faculty of Medicine)
  • Member of Institutional Biosafety and Biosecurity Committee
    01 Mar 2014 - 31 Mar 2017 (University Malaya)
  • Biosafety Facilitator
    01 Jan 2010 - 31 Dec 2016 (Department of Medical Microbiology, Faculty of Medicine)
  • Course coordinator for programme MFEB 2404, Bachelor of Biomedical Science
    22 Jan 2016 - 31 Dec 2016 (Department of Medical Microbiology, Faculty of Medicine)
  • Member of the Advanced Imaging Unit Management Committee
    01 Dec 2013 - 30 Nov 2016 (Dean Office, Faculty of Medicine)
  • Technical Manager for TIDREC Surveillance Laboratory
    23 Sep 2014 - 22 Sep 2016 (University Malaya)
  • Ahli J/K Kecil Biosafety and Biosecurity - Training Manual
    20 Aug 2015 - 19 Aug 2016 (National)
  • Acting Chairman, Faculty of Medicine Institutional Animal Care and Use Committee
    01 Jan 2016 - 31 May 2016 (Dean Office, Faculty of Medicine)
  • Advisory member for Animal Experimental Unit
    13 Feb 2012 - 12 Feb 2016 (Dean Office, Faculty of Medicine)
  • Member of Faculty of Medicine, Central Facilities Committee
    27 Jan 2014 - 26 Jan 2016 (Dean Office, Faculty of Medicine)
  • Deputy Director
    15 Apr 2014 - 31 Dec 2015 (Tropical Infectious Diseases Research & Education Centre (TIDREC), Deputy Vice-Chancellor (Research and Innovation))
  • Ahli J/K Kecil Biosafety and Biosecurity - Policy & Guidelines
    01 Apr 2014 - 31 Mar 2015 (National)
  • Course coordinator for programme MFEB 3403, Bachelor of Biomedical Science
    06 Jul 2009 - 29 Aug 2014 (Department of Medical Microbiology, Faculty of Medicine)
  • Course coordinator for programme MTEJ 1120, Bachelor of Nursing Sciences
    13 Feb 2012 - 29 Aug 2014 (Department of Medical Microbiology, Faculty of Medicine)
  • Member of Faculty of Medicine, Institutional Animal Care and Use Committee
    01 Aug 2012 - 31 Jul 2014 (Dean Office, Faculty of Medicine)
  • Department Quality Manager
    13 Jun 2012 - 01 Jul 2014 (Department of Medical Microbiology, Faculty of Medicine)
  • PBL coordinator (Medical Microbiology) for MBBS Year II
    01 Dec 2011 - 01 Jul 2014 (Department of Medical Microbiology, Faculty of Medicine)
  • Deputy Chairman of Institutional Biosafety Committee
    01 Nov 2012 - 31 Oct 2013 (University Malaya)
  • Ahli J/K Scientific Programme 8th A-PBA Biosafety Conference
    22 Apr 2013 - 25 Apr 2013 (International)
  • Member of Institutional Biosafety Committee
    01 Dec 2010 - 31 Oct 2012 (University Malaya)

MEMBERSHIPS

  • MALAYSIAN SOCIETY FOR MICROBIOLOGY, MEMBER
    Since 2012 (National)
  • MALAYSIAN BIOSAFETY AND BIOSECURITY ASSOCIATION, MEMBER
    Since 2010 (National)

AWARD AND STEWARDSHIP

  • Conference Award - Nipah Virus International Conference, Singapore, 2019
    Coalition for Epidemic Preparedness Innovations (CEPI), 2019 (International)
  • Travel Award - Technical Writing and Grantsmanship Program Workshop 1
    US Defense Threat Reduction Agency (DTRA) Biological Threat Reduction Program (BTRP) and Malaysian One Health University Network (MyOHUN), 2019 (National)
  • Travel award to Asia Pacific Biosafety Association 12th Biosafety Conference 2017
    United States Department of State, 2017 (International)
  • Travel award to Asia Pacific Biosafety Association 10th Biosafety Conference 2015
    United States Department of State, 2015 (International)
  • CERTIFICATE OF EXCELLENT SERVICE
    University of Malaya, 2014 (University)
  • Travel award to Asia Pacific Biosafety Association 9th Biosafety Conference 2014
    United States Department of State, 2014 (International)
  • EXCELLENCE SERVICE AWARD
    University of Malaya, 2013 (University)
  • Anugerah Perkhidmatan Cemerlang
    Universiti Malaya, 2013 (University)
  • CERTIFICATE OF EXCELLENT SERVICE
    University of Malaya, 2012 (University)
  • Travel award to attend the Biosafety and Biosecurity Training Course 2012 at Fort Collins, Colorado, U.S.
    Biosafety Engagement Program, Department of State, U.S., 2012 (International)
  • Travel award to American Society for Microbiology 112th General Meeting at San Francisco, California, U.S.
    Biosafety Engagement Program, Department of State, U.S., 2012 (International)
  • Travel award to Asia Pacific Biosafety Association 6th Biosafety Conference 2011
    National Institutes of Health, U.S., 2011 (International)
  • Travel award to attend IANIS 2010 2nd International Conference on Neuroinfection and Worldwide Impact, St Denis, Reunion Island
    Embassy of France, Malaysia, 2010 (National)
  • Travel award to Train the Trainer Course in Laboratory Biosafety Principles and Practices, Singapore Polytechnic Institute, Singapore
    Consolidated Safety Services, U.S. and U.S. National Institutes of Health, 2010 (International)
  • Travel award to attend BSL3 Science and Safety Course (40-hour biosafety training), Emory University, Atlanta, Georgia, U.S.
    Biosafety Engagement Program, Department of State, U.S., 2010 (International)
  • Member of Nipah Encephalitis Investigation Team, Universiti Malaya as joint recipient winners of the Inaugural Merdeka Award 2008 under the Health, Science and Technology Category.
    ExxonMobil, PETRONAS and Shell, 2009 (National)
  • 2nd prize winner for 2008 Merck Young Scientist Award.
    Merck Sdn Bhd, 2008 (National)
  • Research attachment to Institute of Microbiology, University of Greifswald, Germany
    National Science Fellowship, Ministry of Science, Technology and Innovation of Malaysia, 2004 (National)
  • Travel award for Pasteur-Asia Virology course 2004 in HKU-Pasteur Research Centre, Hong Kong
    Institut Pasteur Paris and HKU-Pasteur Research Centre, 2004 (International)
  • National Science Fellowship
    Ministry of Science, Technology and the Environment of Malaysia, 2001 (National)

PUBLICATIONS

Article in Journal
  1. Cheong HC, Cheok YY, Chan YT, Tang TF, Sulaiman S, Looi CY, Gupta R, Arulanandam B, Chang LY, Wong WF. Chlamydia trachomatis plasmid-encoding Pgp3 protein induces secretion of distinct inflammatory signatures from HeLa cervical epithelial cells (2023). BMC Microbiology. 23:58.
  2. Cheong HC, Sulaiman S, Looi CY, Chang LY, Wong WF. Chlamydia infection remodels host cell mitochondria to alter energy metabolism and subvert apoptosis (2023). Microorganisms. 11:1382.
  3. Phoon WH, Bell-Sakyi L, AbuBakar S, Chang LY. Experimental infection of tick cells with Nipah virus (2023). Tropical Biomedicine. 40:29-36.
  4. Hassan NA, Noor Badi FA, Mohd-Shaharuddin N, Wan Yusoff WS, Lim YAL, Chua KH, Sidi Omar SFN, Chang LY, Majid HA, Ngui R (2022). A conventional multiplex PCR for the detection of four common soil-transmitted nematodes in human feces: development and validation. Tropical Biomedicine. 39:135-143.
  5. Liew, Y. J. M., Ibrahim, P. A. S., Ong, H. M., Chong, C. N., Tan, C. T., Schee, J. P., G mez Rom n, R., Cherian, N. G., Wong, W. F., & Chang, L.-Y. (2022). The Immunobiology of Nipah Virus. Microorganisms, 10(6), 1162. https://doi.org/10.3390/microorganisms10061162
  6. Barathan M, Riazalhosseini B, Iyadorai T, Vellasamy KM, Vadivelu J, Chang LY, Zulpa AK, Shankar EM. (2021) Comparative expression of inflammatory and apoptotic biosignatures in chronic HBV patients with and without liver cirrhosis. Microbial Pathogensis, 161:105231.
  7. Tiong V, Loong SK, Mohamad Wali, HA, Tan KK, Jee PF, Lim FS, Khoo JJ, Wong PF, Chang LY, AbuBakar S (2021). Isolation of Streptococcus cuniculi from corneal lesion in laboratory-raised mice. Journal of Veterinary Medical Science. 83:280-284.
  8. Ngui R, Hassan NA, Chang LY, Teh CSJ, Chua KH, Kee BP, Hoe SZ, Lim YAL (2020). Toxoplasma gondii infection among selected indigenous community in Sarawak, East Malaysia. Tropical Biomedicine. 37:155-164.
  9. Ngui, R., Hassan, N. A., Nordin, N. M. S., Mohd-Shaharuddin, N., Chang, L. Y., Teh, C. S. J., . . . Lim, Y. A. L. (2020). Copro-molecular study of Entamoeba infection among the indigenous community in Malaysia: A first report on the species-specific prevalence of Entamoeba in dogs. Acta Trop, 204, 105334. https://www.ncbi.nlm.nih.gov/pubmed/31926914. doi:10.1016/j.actatropica.2020.105334
  10. Yong MY, Lee SC, Ngui R, Lim YA, Phipps ME, Chang LY. Seroprevalence of Nipah virus infection in Peninsular Malaysia. The Journal of Infectious Diseases 2020, 221 (Suppl 4): S370-S74.
  11. Yong MY, Lee SC, Ngui R, Lim YAL, Phipps ME, Chang LY (2020). Seroprevalence of Nipah virus infection in Peninsular Malaysia. Journal of Infectious Diseases. 221:S370-374.
  12. Cheong, H. C., Yap, P. S. X., Chong, C. W., Cheok, Y. Y., Lee, C. Y. Q., Tan, G. M. Y., . . . Wong, W. F. (2019). Diversity of endocervical microbiota associated with genital Chlamydia trachomatis infection and infertility among women visiting obstetrics and gynecology clinics in Malaysia. PLoS One, 14(11), e0224658. doi:10.1371/journal.pone.0224658
  13. Tiong V, Shu MH, Wong WF, AbuBakar S, Chang LY (2018). Nipah virus infection of immature dendritic cells increases its transendothelial migration across human brain microvascular endothelial cells. Frontiers in Microbiology, 9:2747.
  14. Barathan M, Mohamed R, Vadivelu J, Chang LY, Ramachandran V, Krishnan J, Sigamani P, Saeidi A, Ravishankar Ram M, Velu V, Larsson M, Shankar EM. (2017) CD8+ T cells of chronic HCV-infected patients express multiple immune checkpoints following stimulation with HCV peptides. Cellular Immunology, 313:1-9.
  15. Jee PF, Chen FZ, Shu MH, Wong WF, Rahim RA, AbuBakar S, Chang LY. (2017) Insertion of single-chain variable fragment (scFv) peptide linker improves surface display of influenza hemagglutinin (HA1) in non-recombinant Lactococcus lactis. Biotechnology Progress, 33:154-162.
  16. Jee PF, Tiong V, Shu MH, Khoo JJ, Wong WF, Rahim RA, AbuBakar S, Chang LY. (2017) Oral immunization of a non-recombinant Lactococcus lactis Surface displaying influenza hemagglutinin 1 (HA1) induces mucosal immunity in mice. PLoS One, 12:e0187718.
  17. Khoo JJ, Lim FS, Tan KK, Chen FS, Phoon WH, Khor CS, Pike BL, Chang LY, AbuBakar S. (2017) Detection in Malaysia of a Borrelia sp From Haemaphysalis hystricis (Ixodida: Ixodidae). Journal of Medical Entomology, 54:1444-1448.
  18. Lam CW, AbuBakar S, Chang LY. (2017) Identification of Nipah virus G glycoprotein cell binding domain using phage display system. Journal of Virological Methods, 243:1-9.
  19. Lim FS, Khoo JJ, Chen FZ, Bell-Sakyi L, Khor CS, Chang LY, AbuBakar S. (2017) Initiation of primary cell cultures from embryonic Haemaphysalis bispinosa ticks. Systematic and Applied Acarology, 22:323-332.
  20. Tan KK, Tan YC, Chang LY, Lee KW, Nore SS, Yee WY, Hoh CC, AbuBakar S. (2017) Geographical distribution of Brucella melitensis inferred from rpoB gene variation. Journal of Infection in Developing Countries, 11:420-425.
  21. Tiong V, Lam CW, Phoon WH, AbuBakar S, Chang LY. (2017) Serum from Nipah virus patients recognizes recombinant viral proteins produced in Escherichia coli. Japanese Journal of Infectious Diseases, 701:26-31.
  22. Barathan M, Mohamed R, Vadivelu J, Chang LY, Saeidi A, Yong YK, Tan HY, Ravishankar Ram M, Kaliappan G, Velu V, Larsson M, Shankar EM. (2016) Peripheral loss of CD8+CD161++TCRV 7 2+ mucosal-associated invariant T cells in chronic hepatitis C virus-infected patients. European Journal of Clinical Investigation, 46:170-180.
  23. Khoo JJ, Chen FZ, Kho KL, Ahmad Shanizza AI, Lim FS, Tan KK, Chang LY, AbuBakar S. (2016) Bacterial community in Haemaphysalis ticks of domesticated animals from the Orang Asli communities in Malaysia. Ticks and Tick-borne Diseases, 7:929-937.
  24. Khoo JJ, Khor CS, Chen FZ, Lim, FS, Phoon WH, Pike B, Chang LY, AbuBakar S. (2016) Coxiella detection in ticks from wildlife and livestock in Malaysia. Vector-Borne and Zoonotic Diseases, 16:744-751.
  25. Ong GH, Choh LC, Vellasamy KM, Mariappan V, Chang LY, Vadivelu J. (2016) Experimental phage therapy on Burkholderia pseudomallei infection. PLoS One, 11:e0158213.
  26. Siaw XJS, Jee PF, Song, AA, Chang LY, Khatijah Y, AbuBakar S, Rahim RA. (2016) Oral vaccine of Lactococcus lactis harbouring pandemic H1N1 2009 haemagglutinin1 and nisP anchor fusion protein elevates anti-HA1 sIgA levels in mice. Biotechnology Letters, 38:793-799.
  27. Tan GMY, Lim HJ, Yeow TC, Looi CY, Gupta R, Arulanandam BP, AbuBakar S, Sabet NS, Chang LY, Wong WF. (2016) Temporal proteomic profiling of Chlamydia trachomatis-infected HeLa-229 human cervical epithelial cells. Proteomics, 16:1347-1360.
  28. Hotez PJ, Bottazzi ME, Strych U, Chang LY, Lim YAL, Goodenow MM, AbuBakar S. (2015) Neglected tropical diseases among the Association of Southeast Asian Nations (ASEAN): Overview and update. PLoS Neglected Tropical Diseases, 9:e0003575.
  29. Lani R, Mohd Rahim NF, Hassan H, Chang LY, AbuBakar S, Zandi K. First report on the seroprevalence of the Crimean-Congo haemorrhagic fever virus, a tick-borne virus, in Malaysia's Orang Asli population. European Review for Medical and Pharmacological Sciences, 19:461-466.
  30. Muttiah B, Gopal K, Mohamed R, Ellegard R, Saeidi A, Vadivelu J, Ansari AW, Rothan HAm Ravishankar Ram M, Zandi K, Chang LY, Vignesh R, Che KF, Kamarulzaman A, Velu V, Larsson M, Kamarul T, Shankar EM. (2015) Chronic hepatitis C virus infection triggers spontaneous differential expression of biosignatures associated with T-cell exhaustion and apoptosis signaling in peripheral blood mononucleocytes. Apoptosis, 20:466-480.
  31. Muttiah B, Mohamed R, Vadivelu J, Chang LY, Saeidi A, Gopal K, Velu V, Larsson M, Shankar EM. (2015) Increased frequency of late- senescent T cells lacking IL-7 receptor in chronic hepatits C infection. European Journal of Clinical Investigation, 45:466-474.
  32. Tan KK, Sy AKD, Tandoc AO, Khoo JJ, Sulaiman S, Chang LY, AbuBakar S. (2015) Independent emergence of the Cosmopolitan Asian Chikungunya virus, Philippines 2012. Nature Scientific Report, 5:12279.
  33. Tan KK, Tan YC, Chang LY, Lee KW, Nore SS, Yee WY, Mat Isa NM, Jafar FL, Hoh CC, AbuBakar S. (2015) Full genome SNPs-based phylogenetic analysis revealed the origin and global spread of Brucella melitensis. BMC Genomics, 16:93.
  34. Barathan M, Mohamed R, Vadivelu J, Larsson M, Velu V, Saeidi A, Chang LY, Shankar EM. (2014) Hepatitis C virus infection contributes to impregnation of markers of immune inhibition: potential preludes underlying viral latency and persistence. BMC Infect Dis, 14 (Suppl 3) P3.
  35. Lani R, Moghaddam E, Haghani A, Chang LY, AbuBakar S, Zandi K. (2014) Tick-borne viruses: A review from the perspective of therapeutic approaches. Tick and Tick-borne Diseases, 5:457-465.
  36. Marlina S, Mohd Razi SF, Lani R, Khor CS, Mohd Rahim NF, Hassan H, Chang LY, AbuBakar S, Zandi K. (2014) Seroprevalence screening for the West Nile virus in Malaysia's Orang Asli population. Parasites & Vectors, 7:597.
  37. Wong WF, Looi CY, Kon S, Mohaved E, Funaki T, Chang LY, Satake M, Kohu K. (2014) T-cell receptor signaling induces proximal Runx1 transactivation via a calcineurin-NFAT pathway. European Journal of Immunology, 44:894-904.
  38. AbuBakar S, Teoh BT, Sam SS, Chang LY, Johari J, Hooi PS, Lakhbeer-Singh HK, Italiano CM, Omar SF, Wong KT, Ramli N, Tan CT. (2013) Outbreak of human infection with Sarcocystis nesbitti, Malaysia 2012. Emerging Infectious Diseases, 19:1989-1991.
  39. Tiong VJ, AbuBakar S, Chang LY. (2013) Permissiveness and survivability studies of Nipah virus infection of human monocytic THP-1 cells suggest a role in virus spread. Journal of Health and Translational Medicine 16:17.
  40. Abdullah S, Chang LY, Rahmat K, Goh KJ, Tan CT. (2012) Late-onset Nipah virus encephalitis 11 years after the initial outbreak: A case report. Neurology Asia 17:71-74.
  41. Othman R, Hana-Marlin M, Chang LY. (2010) Proteomics analysis of Polygonum minus leaves. Journal of Biotechnology, 150:S484.
  42. Sohayati AR, Sharifah SH, Olivial KJ, Maizan M, Chang LY, Latiffah H, Arshad SS, Sharina M, Syamsiah AK, Zaini CM, Epstein JH, Field HE, Daszak P, HERG. (2010) Genetic characterization of Nipah virus isolated from naturally infected Pteropus vampyrus in Malaysia. Emerging Infectious Diseases 16:1990- 1993.
  43. Chang LY, AbuBakar S. (2009) Nipah virus: Phylogeny and replication. Neurology Asia 14:63-66.
  44. Sharifah SH, Sohayati AR, Maizan M, Chang LY, Sharina M, Syamsiah AK, Latiffah K, Arshad SS, Zaini CM, Humes F, Daszak P, Epstein J. (2009) Genetic characterization of a Nipah virus isolated from a Pteropus vampyrus in Malaysia. Neurology Asia 14:67-69.
  45. Chang LY, MohdAli AR, Sharifah SH, AbuBakar S. (2007) Human neuronal cell protein responses to Nipah virus infection. Virology Journal 4:54.
  46. AR Raha, Chang LY, Sipat A, Yusoff K, Haryanti T. (2006) Expression of a thermostable xylanase gene from Bacillus coagulans ST-6 in Lactococcus lactis. Letters in Applied Microbiology 42:210-214.
  47. Chang LY, MohdAli AR, Sharifah SH, AbuBakar S. (2006) Nipah virus RNA synthesis in cultured pig and human cells. Journal of Medical Virology 78:1105-1112.
  48. Chang LY, MohdAli AR, Sharifah SH, AbuBakar S. (2006) Quantitative estimation of Nipah virus replication kinetics in vitro. Virology Journal 3:47.
  49. AbuBakar S, Chang LY, MohdAli AR, Sharifah SH, Yusoff K, Zamrod Z. (2004) Isolation and molecular identification of Nipah virus strains from pigs. Emerging Infectious Disease 10:2228-2230.
  50. AbuBakar S, Azmi A, Misbah S, Chang LY. (2002) Antigenic cell associated Dengue 2 virus proteins detected in vitro using dengue fever patients sera. Malaysian Journal of Pathology 24(1):29-36.
Chapter in Books
  1. Chang LY, Tan CT. Nipah virus infection in Viral Infections of the Human Nervous System edited by Alan C Jackson.
Article in Proceeding
  1. Tiong VJ, Shu MH, Abd Rahman H, Wong WF, AbuBakar S, Chang LY. Role of immature dendritic cells in the dissemination of Nipah virus. Abstract submitted to 10th Leiden International Medical Students Conference, Leiden, Netherlands, 2017, p. 208
  2. Jee PF, Chen FS, Shu MH, Tiong V, Khoo JJ, Wong WF, Raha AR, AbuBakar S, Chang LY. Surface display of the HA1 on Lactococcus lactis: A potential candidate vaccine against influenza. Abstract submitted for 5th Asian Federation of Societies for Lactic Acid Bacteria International Symposium, Taipei, Taiwan, 2016, p. 36
  3. Pike BL, Chang LY, Jefree Johari MI, Khor CS, Garica-Rivera JA, AbuBakar S. A cohort study to estimate the risk MERS-CoV poses to travelers and from the Middle East. Abstract submitted for American Society for Tropical Medicine and Hygiene 65th Annual Meeting, Georgia, USA, 2016
  4. Abd-Jamil J, Ngui R, Nellis S, Mohd Zan HA, Fauzi R, Chang LY, Lim YAL, AbuBakar S. Seroprevalence of dengue amongst inhabitants of the semi-forested and forest fringe areas of peninsular Malaysia. Abstract submitted for 16th International Congress on Infectious Diseases, Cape Town, South Africa, 2014, 43.012
  5. Jee PF, AbuBakar S, Wong WF, Raha AR, Chang LY. Development of an influenza candidate vaccine using Lactococcus lactis. Abstract submitted for 16th International Congress on Infectious Diseases, Cape Town, South Africa, 2014, 63.013
  6. Lam CW, AbuBakar S, Abd-Jamil J, Chang LY. Investigation of potential binding sites on Nipah virus glycoprotein. Abstract submitted for 16th International Congress on Infectious Diseases, Cape Town, South Africa, 2014, 51.023
  7. Jee PF, AbuBakar S, Raha AR, Chang LY. Construction of a non-recombinant Lactococcus lactis surface displaying influenza hemagglutinin. Proceedings of the 4th Chula International Workshop on Protein Expression and Purification Strategies, Chulalongkorn University, Bangkok, Thailand 2013, p. 41
  8. Jee PF, AbuBakar S, Raha AR, Chang LY. Immunogenic characterization of influenza A (H1N1) hemagglutinin (HA1) fusion protein expressed in Escherichia coli. Proceedings of the International Congress of the Malaysian Society for Microbiology, Langkawi, Malaysia, 2013, p. 568-569
  9. Lam CW, AbuBakar S, Abd-Jamil J, Chang LY. Investigation of phage-displayed truncated Nipah virus attachment glycoprotein interaction with cells Proceedings of the International Congress of the Malaysian Society for Microbiology, Langkawi, Malaysia, 2013, p. 503-504
  10. V Tiong, S AbuBakar, LY Chang. Escherichia coli- expressed recombinant Nipah virus attachment protein maintains its immunogenicity. Proceedings of the International Congress of the Malaysian Society for Microbiology, Langkawi, Malaysia, 2013, p. 605-606
  11. Jee PF, AbuBakar S, Raha AR, Chang LY. Refolded fusion protein consisting of the N-acetylmuramidase (AcmA) anchor region and influenza hemagglutinin (HA1) retains its binding activity. Proceedings for 31st Symposium of the Malaysian Society for Microbiology, Sabah, Malaysia 2012, p. 46
  12. Lam CW, AbuBakar S, Chang LY. Use of a single phagemid vector to produce both phage displayed and soluble form of truncated Nipah virus fusion glycoprotein. Proceedings for 31st Symposium of the Malaysian Society for Microbiology, Sabah, Malaysia 2012, p. 173
  13. Phoon WH, AbuBakar S, Chang LY. Construction and expression of Nipah virus nucleocapsid gene in Escherichia coli. Proceedings for 31st Symposium of the Malaysian Society for Microbiology, Sabah, Malaysia 2012, p. 194
  14. Siaw XJS, Chang LY, Yusoff K, AbuBakar S, Raha AR. Expression of recombinant Lactococcus lactis harbouring pandemic H1N1 2009 harmagglutinin (HA1) viral epitope. Proceedings for 31st Symposium of the Malaysian Society for Microbiology, Sabah, Malaysia 2012, p. 201
  15. Tiong V, AbuBakar S, Chang LY. Permissiveness and survivability studies of Nipah virus infection of human monocytic THP-1 cells suggest a role in virus spread. Proceedings for 31st Symposium of the Malaysian Society for Microbiology, Sabah, Malaysia 2012, p. 204
  16. Jee PF, AbuBakar S, Raha AR, Chang LY. Surface display of influenza virus A antigenic protein, HA1 on Lactococcus lactis MG1363. Proceedings of the International Congress of the Malaysian Society for Microbiology, p. 398
  17. Lam CW, AbuBakar S, Chang LY. Phage display of truncated Nipah virus attachment glycoprotein. Proceedings of the International Congress of the Malaysian Society for Microbiology, p. 188
  18. Ong GH, Chang LY, Vadivelu J. Isolation and characterization of environmental Burkholderia pseudomallei bacteriophage. Proceedings of the International Congress of the Malaysian Society for Microbiology, p. 395
  19. Ooi HW, AbuBakar S, Chang LY. Molecular cloning and transfection studies of Nipah virus V gene. Proceedings of the International Congress of the Malaysian Society for Microbiology, p. 254
  20. Siaw XJS, Chang LY, Mariana NS, Yusoff K, AbuBakar S, Raha AR. Construction of Lactococcus lactis vector harbouring pandemic H1N1 2009 haemagglutinin viral epitope. Proceedings of the International Congress of the Malaysian Society for Microbiology, p. 396
  21. Tiong V, Lam CW, Ooi HW, Phoon WH, Lew MH, AbuBakar S, Chang LY. Production of recombinant Nipah virus proteins and its application in diagnosis of a relapse case of Nipah virus infection. Proceedings of the International Congress of the Malaysian Society for Microbiology, Penang, Malaysia 2011, p. 331
  22. Sharida S, Kerk SK, Zulqarnain M, Chang LY. Kinetics of protein expression patterns in kesum leaves of Polygonum minus. Abstract submitted for 18th Scientific Meeting of Malaysian Society for Molecular Biology and Biotechnology, Kuala Lumpur, Malaysia 2009, p. 45.
  23. Chang LY, Sharifah SH, AbuBakar S. Kinetics of Nipah virus RNA synthesis. Proceedings of the 30th Symposium of Malaysian Society for Microbiology, Kuantan, Malaysia 2008, p. 30.
  24. Chang LY, Sharifah SH, AbuBakar S. Molecular and genetic characterization of Nipah virus. Abstract submitted for the Nipah Virus Colloquium 2008, Kuala Lumpur, Malaysia 2008.
  25. Hana Marlin M, Chang LY, Othman R. Protein profiling of Polygonum minus leaves. Proceedings of the 5th Malaysian International Conference on Essential Oils, Fragrance and Flavour Materials, Kuala Lumpur, Malaysia 2008, p. 42.
  26. Sharifah SH, Sohayati AR, Maizan M, Chang LY, Sharina M, Syamsiah AK, Latiffah K, Arshad SS, Hughes T, Daszak P, Epstein J, Aziz AJ. Molecular characterization of a recrudesced Nipah virus isolated from Pteropus vampyrus. Abstract submitted for the Nipah Virus Colloquium 2008, Kuala Lumpur, Malaysia 2008.
  27. AbuBakar S, Chang LY, Sharifah SH. Pathogenesis of Nipah virus infection. Proceedings of the 2nd Regional Conference on Molecular Medicine, Kuala Lumpur, Malaysia 2007, p. 17.
  28. Chang LY, Sharifah SH, AbuBakar S. Host cellular responses in Nipah virus infection. Proceedings of the 2nd Regional Conference on Molecular Medicine, Kuala Lumpur, Malaysia 2007, p. 59.
  29. Chang LY, MohdAli AR, Hassan SS and AbuBakar S. Identification of human neuronal cell protein responses to Nipah virus infection. Proceedings of the Joint 3rd AOHUPO and 4th Structural Biology and Functional Genomics Conference, National University of Singapore, Singapore 2006
Other Publications
  1. Hassall, M., Bentley, E.M., Cherry, C., Bernasconi, V., Atkinson, E., Rigsby, P., Page, M., Chang, L.Y., Ong, H.M., Satter, S.M., Rahman, M.Z., Killip, M., Jackson, D., Roman, R.G., Zala, V., Avumegah, M.S., Mattiuzzo., G., and the collaborative study participants. (2023). Establishment of the First WHO International Standard for anti-Nipah virus antibody. (WHO/BS/2023.2458). World Health Organization. - Technical Report
  2. Chang LY. Defense against coronaviruses. Mass media in Star NIE. 22 July 2020. P. 15 - Mass Media(Newspaper,Radio,Tv,Popular Magazine)
  3. Chang LY. Penyelidikan menghalang wabak virus Nipah. Mass media in MEGA Utusan Malaysia, 15 October 2009, p. 2-3. - Mass Media(Newspaper,Radio,Tv,Popular Magazine)

RESEARCH PROJECT

National
  1. 2022 - 2025, MOSTI-Funding
    Ashield: A Portable Viral Aerosol Filtration System For Clinical Applications (cv1121q1080) ( Co-Researcher)
  2. 2020 - 2023, RU Geran - Fakulti Program
    Investigating Emerging Zoonotic Pathogens In Animals And The Environment Within Orang Asli Communities ( Principal Investigator(PI))
  3. 2020 - 2022, Geran Penyelidikan Fakulti
    Investigating emerging zoonotic pathogens in animals and the environment within Orang Asli communities ( Principal Investigator(PI))
  4. 2020 - 2022, Fundamental Research Grant Scheme (FRGS)
    Insights into the cross-reactivity of 2019 novel human coronavirus and its seroprevalence in Malaysia ( Consultant)
  5. 2018 - 2021, Geran Penyelidikan Fakulti
    Nipah Serosurveillance in Swine using an In-House ELISA based on Recombinant Nipah Virus Antigens ( Principal Investigator(PI))
  6. 2019 - 2021, Fundamental Research Grant Scheme (FRGS)
    Elucidation of the Role of Nipah Virus V Protein as an Immune Antagonist ( Principal Investigator(PI))
  7. 2020 - 2021, Universiti Malaya COVID-19 Related Special Research Grant
    Case Study for Covid-19 Screening in hospitals: Investigation on the transmission of SARS-CoV-2 via aerosol PM2.5 In Indoor Environment ( Consultant)
  8. 2020 - 2021, Universiti Malaya COVID-19 Related Special Research Grant
    Inactivate SARS-CoV2 in dental aerosol generating procedures and coating surfaces ( Consultant)
  9. 2017 - 2020, Geran Penyelidikan Universiti Malaya (UMRG)
    Prevalence of Sexually Transmitted & Rodent-Borne Diseases among Orang Ulu in Sarawak ( Principal Investigator(PI))
  10. 2017 - 2019, Frontier Research Grant
    Inhibitory Receptors Pathway Blockade as a Potential Cancer Therapy ( Consultant)
  11. 2016 - 2017, ScienceFund
    Development of Diagnostic Tools and Therapeutics for Nipah Virus Emergency Management ( Principal Investigator(PI))
  12. 2015 - 2017, Postgraduate Research Grant(PPP)
    Association Between Toll-Like Receptors (tlr) Expression and Human Hepatitis C Virus Persistence ( Principal Investigator(PI))
  13. 2015 - 2016, Postgraduate Research Grant(PPP)
    Construction Of A Non-recombinant Lactococcus Lactis Surface Displaying Influenza Hemagglutinin ( Principal Investigator(PI))
  14. 2015 - 2016, Postgraduate Research Grant(PPP)
    Molecular Characterization Of Nipah Virus Replication In Tick Cells ( Principal Investigator(PI))
  15. 2011 - 2015, UM-MOHE HIR
    Molecular Characterization of the Pathoimmunology of Nipah Virus Infection (Genomics and Molecular Characterization of Tropical Infectious Disease Agents) ( Principal Investigator(PI))
  16. 2011 - 2015, UM-MOHE HIR
    Host Immune Response against Candidate InfluenzaVirus Vaccine (Genomics and MolecularCharacterization of Tropical Infectious DiseaseAgents) ( Principal Investigator(PI))
  17. 2012 - 2015, Geran Penyelidikan Universiti Malaya (UMRG)
    Tick-Borne Emerging Infectious Diseases ResearchProgramme ( Principal Investigator(PI))
  18. 2013 - 2014, Geran Penyelidikan Universiti Malaya (UMRG) - Flagship
    Emergence of Zoonotic Infectious Diseases: Diagnostic, Vaccine Development and Safe Science Research Program ( Consultant)
  19. 2011 - 2013, Fundamental Research Grant Scheme (FRGS)
    A Study to Understand the Dynamic Interactions ofNipah Virus Glycoproteins during Virus Entry ( Principal Investigator(PI))
  20. 2011 - 2013, Postgraduate Research Grant(PPP)
    Phage Display of Truncated Nipah Virus MembraneGlycoproteins for the Investigation of FunctionalInteraction Domains ( Principal Investigator(PI))
  21. 2011 - 2013, Exploratory Research Grant Scheme (ERGS)
    Ticks as an Alternative Vector of Transmission ofNipah Virus ( Principal Investigator(PI))
  22. 2009 - 2012, MOSTI IPHARM R&D Initiatives
    Mapping the Dymanics of Genetic Variations ofMalaysian Inluenza Viruses Towards the Developmentof New Diagnostic and Therapeutic Strategies ( Consultant)
  23. 2009 - 2011, UM (Research University)
    Elucidation of the Molecular Evolutionary Dynamics of Nipah Virus ( Principal Investigator(PI))
  24. 2010 - 2011, Fundamental Research Grant Scheme (FRGS)
    Establishment of Recombinant Phages DisplayingTruncated Nipah Virus Glycoproteins for theInvestigation of Functional Interaction Domains ( Principal Investigator(PI))
  25. 2007 - 2009, MOSTI MGI Initiatives
    Novel Systems Biology Approach Towards Elucidation of Biosynthetic Networks of Secondary Metabolites ( Principal Investigator(PI))
International
  1. 2022 - 2025, International Funding
    Characterizing The Epidemiological Diversity Of Nipah Strains ( Principal Investigator(PI))
  2. 2021 - 2024, International Funding
    Characterization Of Niv-specific Immune Responses In Nipah Survivors And Development Of An Antibody Standard From Nipah Convalescent Sera ( Principal Investigator(PI))
  3. 2017 - 2020, Innovate UK Grant
    A Nipah Vaccine to Eliminate Porcine Reservoirs and Safeguard Human Health ( Consultant)
  4. 2015 - 2016, United States Naval Medical Research Center - Asia
    MERS-CoV Site Evaluation and Cohort Study Preparation in Malaysia ( Consultant)
  5. 2012 - 2015, United States Naval Medical Research Center - Asia
    Epidemiological Research in Malaysia ( Consultant)

CONSULTANCY PROJECT

  • Universiti Malaya Laboratory Safety Training Module, Universiti Malaya
    01 Dec 2019 - 01 Dec 2020 (National)
  • Developing Regulations for Animal Welfare Act and Revision of Animal Welfare Code of Practice, Department of Veterinary Services
    01 Dec 2019 - 01 Dec 2019 (National)
  • International Consultation On Research to Combat Nipah Virus Disease, World Health Organization - South-East Asia
    01 Nov 2018 - 01 Nov 2019 (International)
  • Task Force for Nipah Vaccine Development, Coalition for Epidemic Preparedness Innovations (CEPI)
    01 Nov 2018 - 01 Nov 2019 (International)
  • Malaysian Code of Practice for The Care and Use of Animals for Scientific Purposes, Department of Veterinary Services
    01 Nov 2018 - 01 Nov 2018 (National)
  • Institutionalizing Biosecurity Concepts in Malaysian Universities, Malaysian Biosafety and Biosecurity Association
    01 Nov 2018 - 01 Nov 2018 (National)
  • Development of Training Materials and Tools for Strengthening Biosafety and Biosecurity Competency in South East Asia, Malaysian Biosafety and Biosecurity Association
    01 Dec 2017 - 01 Dec 2017 (National)
  • Strengthening Biosafety and Biosecurity Competency in South East Asia Program - Malaysia, Malaysian Biosafety and Biosecurity Association
    01 Dec 2017 - 01 Dec 2017 (National)
  • Strengthening Biosafety and Biosecurity Competency in South East Asia Program - Malaysia, Malaysian Biosafety and Biosecurity Association
    01 Dec 2016 - 01 Dec 2016 (National)
  • Biosafety and Biosecurity Manual & Code of Conduct Document Development, Institut Biologi Sistem
    01 Nov 2016 - 01 Nov 2016 (National)
  • Pra-Bengkel dan Bengkel Penghasilan Manual Latihan Makmal Biosafety Level 2 Peringkat Kebangsaan, National Public Health Laboratory, Ministry of Health
    01 Dec 2015 - 01 Dec 2015 (National)
  • Perbincangan Ulasan Umum "Malaysia Laboratory Biosafety and Biosecurity Policy and Guideline", National Public Health Laboratory, Ministry of Health
    01 Jan 2014 - 01 Jan 2014 (National)
  • Pra-Bengkel Penghasilan Polisi, Garispanduan dan Senarai Semak Biosafety & Biosecurity Perkhidmatan Makmal Kesihatan Peringkat Kebangsaan, National Public Health Laboratory, Ministry of Health
    01 Dec 2013 - 01 Dec 2013 (National)
  • Sharing Experience Between Eu and Sea Countries On The Reinforcement of Legislations and Regulations in The Field of Biosafety and Biosecurity, as Well as Relevant Laboratories Management Systems Through Regional Centre of Excellence, European Union
    01 Apr 2010 - 01 Apr 2012 (International)
  • Bengkel Penyediaan Mysed (2012-2015) Workplan, Ministry of Health Malaysia
    01 Jan 2012 - 01 Jan 2012 (National)
  • Bengkel Percambahan Fikiran Penyediaan dan Penetapan Biological Weapons (Bw) Selected Agents List Rang Undang-Undang Konvensyen Senjata Biologi (Ru Ksb), Science and Technology Research Institute for Defence
    01 Apr 2011 - 01 Apr 2011 (National)
  • Mosti Ipharm Project Monitoring Team for Technofund Project - Proof of Principle Study: Rapid Detection of Dengue Virus (Single Serotype) by a Laboratory Based Surface Acoustic Wave Biosensor, MOSTI IPharm
    01 Apr 2011 - 01 Apr 2011 (National)

PAPER PRESENTED

INVITED SPEAKER
  1. Combating and Preparing for Tropical Infectious Diseases in Malaysia, CBRNe Summit Asia, Intelligence-Sec Limited (International) (02 Dec 2015 - 04 Dec 2015)
  2. Research on Tropical Infectious Diseases at the Tropical Infectious Diseases Research and Education Centre (TIDREC), University of Malaya, 4th ASIAHORCs Joint Symposium on Biomedical Research, Chungnam National University, Korea (International) (11 Nov 2012 - 14 Nov 2012)
  3. Development of a Food-Grade Influenza Virus Vaccine using Lactococcus lactis, 7th National Infectious Diseases Seminar and Workshop 2012, Universiti Putra Malaysia (National) (05 Nov 2012 - 06 Nov 2012)
ORAL PRESENTER
  1. Construction of a non-recombinant Lactococcus lactis surface displaying influenza hemagglutinin, 4th Chula International Workshop on Protein Expression and Purification Strategies, Chulalongkorn University, Bangkok, Thailand (International) (28 Oct 2013 - 01 Nov 2013)
  2. Refolded fusion protein consisting of the N- acetylmuramidase (AcmA) anchor region and influenza hemagglutinin (HA1) retains its binding activity., 31st Symposium of the Malaysian Society for Microbiology, Malaysian Society for Microbiology (National) (13 Dec 2012 - 15 Dec 2012)
  3. Molecular and genetic characterization of Nipah virus, Nipah Virus Colloquium 2008 (International) (20 Oct 2008 - 21 Oct 2008)
  4. Kinetics of Nipah virus RNA synthesis, 30th Symposium of Malaysian Society for Microbiology (National) (16 Aug 2008 - 19 Aug 2008)
POSTER PRESENTER
  1. Host cellular responses in Nipah virus infection, 2nd Regional Conference on Molecular Medicine (International) (26 Oct 2007 - 28 Oct 2007)
  2. Identification of human neuronal cell protein responses to Nipah virus infection, Joint 3rd AOHUPO and 4th Structural Biology and Functional Genomics Conference (International) (04 Dec 2006 - 07 Dec 2006)
PRESENTER
  1. Molecular characterization of a recrudesced Nipah virus isolated from Pteropus vampyrus, Nipah Virus Colloquium 2008 (International) (20 Oct 2008 - 21 Oct 2008)
  2. Pathogenesis of Nipah virus infection, 2nd Regional Conference on Molecular Medicine (International) (26 Oct 2007 - 28 Aug 2007)

ACADEMIC/PROF. SERVICES

Evaluation
  1. (2022) Review for Manuscript 2086300, International, (Reviewer)
  2. (2022) Reviewer for Manuscript D-22-00253, International, (Reviewer)
  3. (2022) Panel Reviewer for Umsc Ca.R.E Fund (Research Grant) Cycle 1/2022, University, (Internal Evaluator)
  4. (2022) Evaluation Panel Member for Wellcome Trust Grant Funding Application 2022, University, (Internal Evaluator)
  5. (2022) Member of Niaid Resource-Related Projects (R24) Application Review, International, (External Evaluator)
  6. (2021) Panel Penilai Mtsf Peringkat UM, University, (Internal Evaluator)
  7. (2021) Panel Penilai Frgs Fasa 1/2021 Peringkat UM, University, (Internal Evaluator)
  8. (2019) Evaluation Panel for FRGS Phase 1/2019 for Faculty of Medicine, Universiti Malaya , (Reviewer)
  9. (2019) Evaluation Panel for GPF and UMSC CARE Fund 2019, Faculty of Medicine, Universiti Malaya, (Reviewer)
  10. (2019) IPT FRGS Evaluation Panel for NIBM, Ministry of Science, Technology and Innovation, Malaysia , (Reviewer)
  11. (2015) Evaluation of Geran Peruntukan Penyelidikan Pascaijazah (PPP) Fakulti Perubatan , (Evaluator)
  12. (2012) Evaluation of Geran Peruntukan Penyedlikan Pascaijazah (PPP) Fakulti Perubatan , (Evaluator)
  13. (2012) 3rd Malaysian Symposium on Biomedical Sciences 2012 , (Poster Judge)
  14. (2012) 31st Malaysian Society for Microbiology Symposium, (Poster Judge)
  15. (2011) Project Monitoring Team for TechnoFund Project - Proof of Principle Study: Rapid Detection of Dengue Virus (Single Serotype) By A Laboratory Based Surface Acoustic Wave Biosensor , (Panel Member)
  16. (2011) Judge for Poster Presentations at the International Congress of the Malaysian Society for Microbiology, Penang, Malaysia , (Poster Judge)
Contribution to external organisation
  1. (2022) Komen Untuk Draf Peraturan Kebajikan Haiwan (Penggunaan Haiwan Dalam Penyelidikan, Ujian dan Pengajaran), National, (Expert Advisor)
  2. (2019) Invitation to participate at Biological Standards and Assays in Oslo, Norway, Coalition for Epidemic Preparedness Innovations (CEPI), International
  3. (2018) Institutionalizing Biosecurity Concepts in Malaysian Universities, Sandia National Laboratories, National
  4. (2018) Faculty of Medicine - Institutional Animal Care and Use Committee, Universiti Malaya
  5. (2017) IFBA Biorisk Management Certiciation - Phase 3, Malaysian Biosafety and Biosecurity Association, International
  6. (2017) Strengthening Biosafety and Biosecurity Competency in South East Asia Program - Malaysia, Malaysian Biosafety and Bioescurity Association, National
  7. (2017) IFBA Biorisk Management Certiciation - Phase 1, Malaysian Biosafety and Biosecurity Association, International
  8. (2017) Biorisk Management Course, Jabatan Kimia Malaysia, National
  9. (2017) IFBA Biorisk Management Certiciation - Phase 2, Malaysian Biosafety and Biosecurity Association, International
  10. (2017) Development of Training Materials and Tools for Strengthening Biosafety and Biosecurity Competency in South East Asia Program, Malaysian Biosafety and Biosecurity Association, International
  11. (2017) Faculty of Medicine - Institutional Animal Care and Use Committee, Universiti Malaya
  12. (2017) Internal Audit MS ISO 15189, Department of Medical Microbiology, University of Malaya Medical Center
  13. (2017) Strengthening Biosafety and Biosecurity Competency in South East Asia Program - Malaysia, Malaysian Biosafety and Biosecurity Association
  14. (2017) IFBA Biorisk Management Certification Workshop - Phase 2, Malaysian Biosafety and Biosecurity Association
  15. (2017) Universiti Malaya Institutional Biosafety and Biosecurity Committee, Universiti Malaya
  16. (2017) IFBA Biorisk Management Certification Workshop - Phase 1, Malaysian Biosafety and Biosecurity Association
  17. (2017) IFBA Biorisk Management Certification Workshop - Phase 3, Malaysian Biosafety and Biosecuirty Association
  18. (2017) Biorisk Management Course, Jabatan Kimia Malaysia
  19. (2016) Strengthening Biosafety and Biosecurity Competency in South East Asia Program - Malaysia, Malaysian Biosafety and Biosecurity Association, National
  20. (2016) Biosafety and Biosecurity Training, TIDREC Universiti Malaya
  21. (2016) AAALAC International recertification site visit - Animal Experimental Unit and Satellite Facilities, Faculty of Medicine, University Malaya
  22. (2016) Biosafety and Biosecurity Manual & Code of Conduct Document Development, Universiti Kebangsaan Malaysia
  23. (2015) National Laboratory Biosafety & Biosecurity Training Manual, National Public Health Laboratory, Ministry of Health, National
  24. (2015) Faculty of Medicine - Institutional Animal Care and Use Committee, Universiti Malaya
  25. (2015) Institutional Biosafety and Biosecurity Committee, Universiti Malaya
  26. (2015) Pra-Bengkel dan Bengkel Penghasilan Manual Latihan Makmal Biosafety Level 2 Peringkat Kebangsaan, National Public Health Laboratory, Ministry of Health
  27. (2014) Malaysia Laboratory Biosafety and Biosecurity Policy and Guidelines, National Public Health Laboratory, Ministry of Health, National
  28. (2014) Universiti Malaya Policies and Procedures on Biosafety and Biosecurity, Universiti Malaya
  29. (2014) Perbincangan ulasan umum draf "Malaysia Laboratory Biosafety and Biosecurity Policy and Guidelines", National Public Health Laboratory, Ministry of Health
  30. (2014) Institutional Biosafety and Biosecurity Committee, Universiti Malaya
  31. (2013) Knowledge development and transfer of best practice on biosafety/biosecurity/biorisk management, European Union Chemical, Biological, Radiological and Nuclear Centers of Excellence Initiative, International
  32. (2013) National Laboratory Biosafety & Biosecurity Policy and Guidelines, National Public Health Laboratory, Ministry of Health, National
  33. (2013) Bengkel Penghasilan Polisi, Garispanduan dan Senarai Semak Biosafety & Biosecurity Perkhidmatan Makmal Kesihatan Peringkat Kebangsaan, National Public Health Laboratory, Ministry of Health
  34. (2012) EU-ASEAN cooperation on Chemical, Biological, Radiological and Nuclear Centres of Excellence (CBRN CoE), Ministry of Foreign Affairs Malaysia, National
  35. (2012) National Strategic Plan for Emerging Diseases, Ministry of Health Malaysia
  36. (2012) Insitutional Animal Care and Use Committee, Universiti Malaya
  37. (2012) Institutional Biosafety Committee, Universiti Malaya
  38. (2012) Bengkel Kesedaran Rang Undang-Undang Konvensyen Senjata Biology dan Toksin (RUU KSBT) Siri II 2012, Science and Technology Research Institute for Defence, Ministry of Defence Malaysia
  39. (2012) AAALAC accreditation of Animal Experimental Unit and Satellite Facilities, Faculty of Medicine, Universiti Malaya
  40. (2011) EU-ASEAN cooperation on field of Biosafety and Biosecurity through Regional Centre of Excellence, European Commission, International
  41. (2011) UM-Emory Biorisk Management Training, Tropical Infectious Diseases Research and Education Centre (TIDREC), Universiti Malaya and Biosecurity Engagement Program (BEP), U.S. Department of State
  42. (2011) Bengkel Percambahan Fikiran Penyediaan dan Penetapan Biological Weapons (BW) Selected Agents List Rang Undang-Undang Konvensyen Senjata Biologi (RU KSB), Science and Technology Research Institute for Defence, Ministry of Defence Malaysia
  43. (2011) MMB Laboratory Biosafety - Principles and Practices, Tropical Infectious Diseases Research and Education Centre(TIDREC), Universiti Malaya
  44. (2011) Institutional Biosafety Committee, Universiti Malaya
  45. (2010) Institutional Biosafety Committee, Universiti Malaya
  46. (2010) EU-ASEAN CBRN Regional Centre of Excellence, Ministry of Foreign Affairs Malaysia
  47. (2009) EU-ASEAN cooperation on Chemical, Biological, Radiological and Nuclear (CBRN) centres of excellence and assistance in the field of biosafety/biosecurity, European Commission, International
  48. (2009) Biosafety Training, TIDREC, Universiti Malaya
  49. (2009) Management of Containment Facilities Workshop, Universiti Malaya and Ministry of Natural Resources and Environment Malaysia
Contribution to event
  1. (2022) Guest Panelist, International, (Panelist/Moderator)
  2. (2022) Speaker, University, (Panelist/Moderator)

SUPERVISION

Postgraduate Student
PhD/ Doctoral
  1. (2019) Decrypting the Intricate Interplay between Chlamydia trachomatis and Host Cell Mitochondria, Cheong Heng Choon
  2. (2012) The Role of Leukocytes in the Dissemination of Nipah Virus, Tiong Vunjia
  3. (2011) Influenza Hemagglutinin 1 (HA1) Surface-Displayed on Lactococcus Lactis in the Induction of Protective Mucosal Immunity against Influenza Virus, Jee Pui Fong
  4. (2008) Phylodynamics of Dengue Virus Type 1 in Recurring Dengue Outbreaks in Malaysia, Teoh Boon Teong
  5. (2008) Interleukin-10, Interleukin-12 and Tumor Necrosis Factor-Alpha Gene Polymorphisms in Manifestations of Severe Dengue, Sam Sing Sin
  6. (2008) Dengue Virus Type 3 in Malaysia: Diversity, Origin, and Spread, Tan Kim Kee
Master
  1. (2019) Evaluation Of Amino Acid Changes In Nipah Virus V Protein In Its Function As An Immune Antagonist, Oon Syiak Syin
  2. (2018) ELISA-Based Assay using Recombinant Nipah Virus Antigens for Nipah Surveillance among Indigenous Populations in Peninsular Malaysia, Yong Ming Yen
  3. (2016) Modulation of Host Immune Responses by Chlamydial Plasmid Encoded Pgp3 Protein in Patients with Genital Chlamydia Trachomatis Infections, Cheong Heng Choon
  4. (2013) Studies on Immune Impairment in Chronic Hepatitis C Virus Infection, Barathan Muttiah
  5. (2013) Molecular Characterization of Nipah Virus Replication in Tick Cells, Phoon Wai Hong
  6. (2013) Genome-Wide Investigation of Helicobacter Pylori in RAW 264.7 Cells, Grace Tan Min Yi
  7. (2010) NisP as a Potential Surface Anchor for Pandemic H1N1 2009 Haemagglutini (HA1) Viral Epitope in Lactococcus lactis, Stella Siaw Xiu Joan (M0100103)
  8. (2010) Investigating the Potentials of Phage Therapy for Burkholderia pseudomallei Infections, Ong Guang Han
  9. (2010) Identification of Potential Cell Binding Sites on the Nipah Virus Attachment Glycoprotein using Phage Display System, Lam Chui Wan
  10. (2009) Epidemiologic and Molecular Characteristics of Rotavirus and Norovirus in University Malaya Medical Centre, Malaysia, Lu Kwang Shan
  11. (2008) Construction Of An Infectious Clone Of Japanese Encephalitis Virus Using Modified Pcr-Based Assembly Technique, Mohd Jefree Iskandar Johari
  12. (2007) Protein Profiling of Polygonum minus Leaves, Hana Marlin Mahfodz (M0100101)
  13. (2006) Kinetics of Protein Expression Patterns in Kesum Leaves (Persicaria minus), Sharida Shoib

TEACHING

Doctor Of Philosophy
  1. (2023) MVX8001 - Research Methodology
Master
  1. (2023) MQF7010 - Ethics in Animal Research
  2. (2023) MMX7001 - Research Methodology
  3. (2022) MVX8001 - Research Methodology
  4. (2020) MMX7001 - Research Methodology
  5. (2020) MMX7001 - Research Methodology
  6. (2020) MVX8001 - Research Methodology
  7. (2019) MXGZ6101 - Research Methodology for Research Mode Programmes
  8. (2018) MXGZ6101 - Research Methodology for Research Mode Programmes
  9. (2017) MXGZ6101 - Research Methodology for Research Mode Programmes
  10. (2016) MXGZ6101 - Research Methodology for Research Mode Programmes
  11. (2014) Masters in Pathology
  12. (2014) MXGZ6101 - Research Methodology for Research Mode Programmes
  13. (2013) Masters in Pathology
Bachelor
  1. (2023) MIC3014 - Advanced Medical Microbiology
  2. (2023) MIC3011 - Advances in Medical Virology
  3. (2023) MIC1011 - Biosafety and Biosecurity
  4. (2023) GQM0062 - Human and Microbes - The Global Challenge
  5. (2023) GIM2003 - Introduction to Infectious Diseases
  6. (2023) DIA2005 - Medical Microbiology
  7. (2023) MIC2007 - Microbial Infections
  8. (2022) MIC3011 - Advances in Medical Virology
  9. (2022) MIC1011 - Biosafety and Biosecurity
  10. (2022) DIA2005 - Medical Microbiology
  11. (2020) MIC2006 - Bio-Risk Management for Biomedical Science
  12. (2020) MIC3011 - Advances in Medical Virology
  13. (2020) MIC4010 - Diagnostic Virology
  14. (2020) UMMP - Ummp Block 2 (Foundation)
  15. (2020) UMMP - Ummp Block 2 (Foundation)
  16. (2019) MIC3011 - Advances in Medical Virology
  17. (2019) UMMP - Ummp Block 2 (Foundation)
  18. (2018) DIA2005 - Medical Microbiology
  19. (2018) MBEB4103 - Current Topics in Biomedical Science
  20. (2018) MIC2007 - Microbial Infections
  21. (2018) UMMP - Ummp Block 2 (Foundation)
  22. (2017) DIA2005 - Medical Microbiology
  23. (2017) MBEB3106 - Ethics in Biomedicine
  24. (2017) MBEB4103 - Current Topics in Biomedical Science
  25. (2017) MFEB2404 - Intorductory Diagnostic Virology
  26. (2017) MIC2006 - Bio-Risk Management for Biomedical Science
  27. (2016) DIA2005 - Medical Microbiology
  28. (2016) MBEB3106 - Ethics in Biomedicine
  29. (2016) MFEB3401 - Advanced Medical Virology
  30. (2016) MFEB3403 - Advanced Diagnostic Virology
  31. (2016) MIC2007 - Microbial Infections
  32. (2016) UMMP - Ummp Block 2 (Foundation)
  33. (2015) MFEB3401 - Advanced Medical Virology
  34. (2015) UMMP - Ummp Block 2 (Foundation)
  35. (2014) Medical Microbiology MBBS Paraclinical Core
  36. (2014) DJED2101 - Mikrobiologi Perubatan
  37. (2014) MBEB3106 - Ethics in Biomedicine
  38. (2013) Medical Microbiology MBBS Paraclinical Core
  39. (2013) DJED2101 - Mikrobiologi Perubatan
  40. (2013) MFEB2401 - Microbial Infection (B)
  41. (2013) MFEB2404 - Intorductory Diagnostic Virology
  42. (2013) MFEB3401 - Advanced Medical Virology
  43. (2013) MFEB3403 - Advanced Diagnostic Virology
  44. (2013) UMMP - Ummp Block 2 (Foundation)
  45. (2012) DJED2101 - Mikrobiologi Perubatan
  46. (2012) MFEB2404 - Intorductory Diagnostic Virology
  47. (2012) MFEB3401 - Advanced Medical Virology
  48. (2012) MFEB3403 - Advanced Diagnostic Virology
  49. (2012) MFEB3404 - Advanced Diagnostic Microbiology
  50. (2012) MTEJ1120 - Parasitology and Microbiology
  51. (2011) Medical Microbiology MBBS Paraclinical Core
  52. (2011) DJED2101 - Mikrobiologi Perubatan
  53. (2011) MFEB2404 - Intorductory Diagnostic Virology
  54. (2011) MFEB3402 - Advanced Medical Microbiology
  55. (2011) MFEB3403 - Advanced Diagnostic Virology
  56. (2011) MWEF2111 - Pharmaceutical Microbiology
  57. (2010) Medical Microbiology MBBS Paraclinical Core
  58. (2010) DJED2101 - Mikrobiologi Perubatan
  59. (2010) MFEB3401 - Advanced Medical Virology
  60. (2010) MFEB3402 - Advanced Medical Microbiology (Bacteriology)
  61. (2010) MTEJ2102 - Clinical Sciences
  62. (2009) MFEB3401 - Advanced Medical Virology
Others
  1. (2013) Diploma in Medical Lab Technology

PATENT/IPR

  • A fusion protein and a method for producing thereof
    Patent (National)
  • A fusion fragment encoding an influenza A virus hemagglutinin and a method for preparing the same
    Patent (National)
  • Detection and quantitation method for Nipah and Hendra viruses
    Patent (National)