
Curriculum Vitae
PERSONAL DETAILS
ASSOCIATE PROF. DR. CHANG LI YEN
Associate Professor
- Department of Medical Microbiology
Faculty of Medicine - +603-79675761
- changliyen@um.edu.my
ADMINISTRATIVE DUTIES
(Role),(Level),(Duration)
(Role),(Level),(Duration)
- Chairperson, Faculty of Medicine Institutional Animal Care and Use Committee, University Malaya, 04/07/2018 to 03/07/2020
- Member of Faculty of Medicine, Institutional Animal Care and Use Committee, Faculty, 01/06/2017 to 31/05/2019
- Assistant Chairperson, Faculty of Medicine Institutional Animal Care and Use Committee, University Malaya, 01/05/2017 to 30/04/2019
- Member of Institutional Biosafety and Biosecurity Committee, University Malaya, 01/04/2017 to 31/03/2019
- Deputy Director, UNIVERSITI MALAYA, 01/01/2016 to 01/03/2017
- Member of Faculty of Medicine, Institutional Animal Care and Use Committee, Faculty, 01/06/2015 to 31/05/2017
- Member of Institutional Biosafety and Biosecurity Committee, University Malaya, 01/03/2014 to 31/03/2017
- Course coordinator for programme MFEB 2404, Bachelor of Biomedical Science, Faculty, 22/01/2016 to 31/12/2016
- Acting Chairman, Faculty of Medicine Institutional Animal Care and Use Committee, Faculty, 01/01/2016 to 31/05/2016
- Ahli J/K Kecil Biosafety and Biosecurity - Training Manual, National, 20/08/2015 to 19/08/2016
- Technical Manager for TIDREC Surveillance Laboratory, University Malaya, 23/09/2014 to 22/09/2016
- Member of Faculty of Medicine, Central Facilities Committee, Faculty, 27/01/2014 to 26/01/2016
- Member of the Advanced Imaging Unit Management Committee, Faculty, 01/12/2013 to 30/11/2016
- Advisory member for Animal Experimental Unit, Faculty, 13/02/2012 to 12/02/2016
- Biosafety Facilitator, Faculty, 01/01/2010 to 31/12/2016
- Deputy Director, UNIVERSITI MALAYA, 15/04/2014 to 31/12/2015
- Ahli J/K Kecil Biosafety and Biosecurity - Policy & Guidelines, National, 01/04/2014 to 31/03/2015
- Member of Faculty of Medicine, Institutional Animal Care and Use Committee, Faculty, 01/08/2012 to 31/07/2014
- Department Quality Manager, Faculty, 13/06/2012 to 01/07/2014
- Course coordinator for programme MTEJ 1120, Bachelor of Nursing Sciences, Faculty, 13/02/2012 to 29/08/2014
- PBL coordinator (Medical Microbiology) for MBBS Year II, Faculty, 01/12/2011 to 01/07/2014
- Course coordinator for programme MFEB 3403, Bachelor of Biomedical Science, Faculty, 06/07/2009 to 29/08/2014
- Ahli J/K Scientific Programme 8th A-PBA Biosafety Conference, International, 22/04/2013 to 25/04/2013
- Deputy Chairman of Institutional Biosafety Committee, University Malaya, 01/11/2012 to 31/10/2013
- Member of Institutional Biosafety Committee, University Malaya, 01/12/2010 to 31/10/2012
ACADEMIC QUALIFICATION
(Qualification),(Field),(Institution),(Year)
(Qualification),(Field),(Institution),(Year)
- PHD, (2007) (UM), MOLECULAR VIROLOGY, UNIVERSITI MALAYA (UM)
- MSc(2002) (UPM), BIOLOGI MOLEKUL, UNIVERSITI PUTRA MALAYSIA (UPM)
- BSc(1998) (UPM), BIOTECHNOLOGY, UNIVERSITI PUTRA MALAYSIA (UPM)
SPECIALIZATION
(Area)
(Area)
Area of Expertise
TEACHING
(Course Title),(Level of Study),(Institution),(Academic Session)
(Course Title),(Level of Study),(Institution),(Academic Session)
Teaching
PUBLICATIONS
(Title of publication in APA style)
(Title of publication in APA style)
Refereed Journals
2021
- Tiong V, Loong SK, Mohamad Wali, HA, Tan KK, Jee PF, Lim FS, Khoo JJ, Wong PF, Chang LY, AbuBakar S (2021). Isolation of Streptococcus cuniculi from corneal lesion in laboratory-raised mice. Journal of Veterinary Medical Science. 83:280-284. (WoS)
2020
- Ngui, R., Hassan, N. A., Nordin, N. M. S., Mohd-Shaharuddin, N., Chang, L. Y., Teh, C. S. J., . . . Lim, Y. A. L. (2020). Copro-molecular study of Entamoeba infection among the indigenous community in Malaysia: A first report on the species-specific prevalence of Entamoeba in dogs. Acta Trop, 204, 105334. https://www.ncbi.nlm.nih.gov/pubmed/31926914. doi:10.1016/j.actatropica.2020.105334 (WoS)
- Ngui R, Hassan NA, Chang LY, Teh CSJ, Chua KH, Kee BP, Hoe SZ, Lim YAL (2020). Toxoplasma gondii infection among selected indigenous community in Sarawak, East Malaysia. Tropical Biomedicine. 37:155-164. (WoS)
- Yong MY, Lee SC, Ngui R, Lim YAL, Phipps ME, Chang LY (2020). Seroprevalence of Nipah virus infection in Peninsular Malaysia. Journal of Infectious Diseases. 221:S370-374. (WoS)
2019
- Cheong, H. C., Yap, P. S. X., Chong, C. W., Cheok, Y. Y., Lee, C. Y. Q., Tan, G. M. Y., . . . Wong, W. F. (2019). Diversity of endocervical microbiota associated with genital Chlamydia trachomatis infection and infertility among women visiting obstetrics and gynecology clinics in Malaysia. PLoS One, 14(11), e0224658. doi:10.1371/journal.pone.0224658 (WoS)
2018
- Tiong V, Shu MH, Wong WF, AbuBakar S, Chang LY (2018). Nipah virus infection of immature dendritic cells increases its transendothelial migration across human brain microvascular endothelial cells. Frontiers in Microbiology, 9:2747. (WoS)
2017
- Tiong V, Lam CW, Phoon WH, AbuBakar S, Chang LY. (2017) Serum from Nipah virus patients recognizes recombinant viral proteins produced in Escherichia coli. Japanese Journal of Infectious Diseases, 701:26-31. (WoS)
- Tan KK, Tan YC, Chang LY, Lee KW, Nore SS, Yee WY, Hoh CC, AbuBakar S. (2017) Geographical distribution of Brucella melitensis inferred from rpoB gene variation. Journal of Infection in Developing Countries, 11:420-425. (WoS)
- Jee PF, Chen FZ, Shu MH, Wong WF, Rahim RA, AbuBakar S, Chang LY. (2017) Insertion of single-chain variable fragment (scFv) peptide linker improves surface display of influenza hemagglutinin (HA1) in non-recombinant Lactococcus lactis. Biotechnology Progress, 33:154-162. (WoS)
- Lam CW, AbuBakar S, Chang LY. (2017) Identification of Nipah virus G glycoprotein cell binding domain using phage display system. Journal of Virological Methods, 243:1-9. (WoS)
- Barathan M, Mohamed R, Vadivelu J, Chang LY, Ramachandran V, Krishnan J, Sigamani P, Saeidi A, Ravishankar Ram M, Velu V, Larsson M, Shankar EM. (2017) CD8+ T cells of chronic HCV-infected patients express multiple immune checkpoints following stimulation with HCV peptides. Cellular Immunology, 313:1-9. (WoS)
- Lim FS, Khoo JJ, Chen FZ, Bell-Sakyi L, Khor CS, Chang LY, AbuBakar S. (2017) Initiation of primary cell cultures from embryonic Haemaphysalis bispinosa ticks. Systematic and Applied Acarology, 22:323-332. (WoS)
- Khoo JJ, Lim FS, Tan KK, Chen FS, Phoon WH, Khor CS, Pike BL, Chang LY, AbuBakar S. (2017) Detection in Malaysia of a Borrelia sp From Haemaphysalis hystricis (Ixodida: Ixodidae). Journal of Medical Entomology, 54:1444-1448. (WoS)
- Jee PF, Tiong V, Shu MH, Khoo JJ, Wong WF, Rahim RA, AbuBakar S, Chang LY. (2017) Oral immunization of a non-recombinant Lactococcus lactis Surface displaying influenza hemagglutinin 1 (HA1) induces mucosal immunity in mice. PLoS One, 12:e0187718. (WoS)
2016
- Siaw XJS, Jee PF, Song, AA, Chang LY, Khatijah Y, AbuBakar S, Rahim RA. (2016) Oral vaccine of Lactococcus lactis harbouring pandemic H1N1 2009 haemagglutinin1 and nisP anchor fusion protein elevates anti-HA1 sIgA levels in mice. Biotechnology Letters, 38:793-799. (WoS)
- Barathan M, Mohamed R, Vadivelu J, Chang LY, Saeidi A, Yong YK, Tan HY, Ravishankar Ram M, Kaliappan G, Velu V, Larsson M, Shankar EM. (2016) Peripheral loss of CD8+CD161++TCRV 7 2+ mucosal-associated invariant T cells in chronic hepatitis C virus-infected patients. European Journal of Clinical Investigation, 46:170-180. (WoS)
- Tan GMY, Lim HJ, Yeow TC, Looi CY, Gupta R, Arulanandam BP, AbuBakar S, Sabet NS, Chang LY, Wong WF. (2016) Temporal proteomic profiling of Chlamydia trachomatis-infected HeLa-229 human cervical epithelial cells. Proteomics, 16:1347-1360. (WoS)
- Ong GH, Choh LC, Vellasamy KM, Mariappan V, Chang LY, Vadivelu J. (2016) Experimental phage therapy on Burkholderia pseudomallei infection. PLoS One, 11:e0158213. (WoS)
- Khoo JJ, Chen FZ, Kho KL, Ahmad Shanizza AI, Lim FS, Tan KK, Chang LY, AbuBakar S. (2016) Bacterial community in Haemaphysalis ticks of domesticated animals from the Orang Asli communities in Malaysia. Ticks and Tick-borne Diseases, 7:929-937. (WoS)
- Khoo JJ, Khor CS, Chen FZ, Lim, FS, Phoon WH, Pike B, Chang LY, AbuBakar S. (2016) Coxiella detection in ticks from wildlife and livestock in Malaysia. Vector-Borne and Zoonotic Diseases, 16:744-751. (WoS)
2015
- Lani R, Mohd Rahim NF, Hassan H, Chang LY, AbuBakar S, Zandi K. First report on the seroprevalence of the Crimean-Congo haemorrhagic fever virus, a tick-borne virus, in Malaysia's Orang Asli population. European Review for Medical and Pharmacological Sciences, 19:461-466. (WoS)
- Muttiah B, Gopal K, Mohamed R, Ellegard R, Saeidi A, Vadivelu J, Ansari AW, Rothan HAm Ravishankar Ram M, Zandi K, Chang LY, Vignesh R, Che KF, Kamarulzaman A, Velu V, Larsson M, Kamarul T, Shankar EM. (2015) Chronic hepatitis C virus infection triggers spontaneous differential expression of biosignatures associated with T-cell exhaustion and apoptosis signaling in peripheral blood mononucleocytes. Apoptosis, 20:466-480. (WoS)
- Muttiah B, Mohamed R, Vadivelu J, Chang LY, Saeidi A, Gopal K, Velu V, Larsson M, Shankar EM. (2015) Increased frequency of late- senescent T cells lacking IL-7 receptor in chronic hepatits C infection. European Journal of Clinical Investigation, 45:466-474. (WoS)
- Tan KK, Tan YC, Chang LY, Lee KW, Nore SS, Yee WY, Mat Isa NM, Jafar FL, Hoh CC, AbuBakar S. (2015) Full genome SNPs-based phylogenetic analysis revealed the origin and global spread of Brucella melitensis. BMC Genomics, 16:93. (WoS)
- Hotez PJ, Bottazzi ME, Strych U, Chang LY, Lim YAL, Goodenow MM, AbuBakar S. (2015) Neglected tropical diseases among the Association of Southeast Asian Nations (ASEAN): Overview and update. PLoS Neglected Tropical Diseases, 9:e0003575. (WoS)
- Tan KK, Sy AKD, Tandoc AO, Khoo JJ, Sulaiman S, Chang LY, AbuBakar S. (2015) Independent emergence of the Cosmopolitan Asian Chikungunya virus, Philippines 2012. Nature Scientific Report, 5:12279. (WoS)
2014
- Barathan M, Mohamed R, Vadivelu J, Larsson M, Velu V, Saeidi A, Chang LY, Shankar EM. (2014) Hepatitis C virus infection contributes to impregnation of markers of immune inhibition: potential preludes underlying viral latency and persistence. BMC Infect Dis, 14 (Suppl 3) P3. (WoS)
- Wong WF, Looi CY, Kon S, Mohaved E, Funaki T, Chang LY, Satake M, Kohu K. (2014) T-cell receptor signaling induces proximal Runx1 transactivation via a calcineurin-NFAT pathway. European Journal of Immunology, 44:894-904. (WoS)
- Lani R, Moghaddam E, Haghani A, Chang LY, AbuBakar S, Zandi K. (2014) Tick-borne viruses: A review from the perspective of therapeutic approaches. Tick and Tick-borne Diseases, 5:457-465. (WoS)
- Marlina S, Mohd Razi SF, Lani R, Khor CS, Mohd Rahim NF, Hassan H, Chang LY, AbuBakar S, Zandi K. (2014) Seroprevalence screening for the West Nile virus in Malaysia's Orang Asli population. Parasites & Vectors, 7:597. (WoS)
2013
- AbuBakar S, Teoh BT, Sam SS, Chang LY, Johari J, Hooi PS, Lakhbeer-Singh HK, Italiano CM, Omar SF, Wong KT, Ramli N, Tan CT. (2013) Outbreak of human infection with Sarcocystis nesbitti, Malaysia 2012. Emerging Infectious Diseases, 19:1989-1991. (WoS)
- Tiong VJ, AbuBakar S, Chang LY. (2013) Permissiveness and survivability studies of Nipah virus infection of human monocytic THP-1 cells suggest a role in virus spread. Journal of Health and Translational Medicine 16:17. (SCOPUS)
2012
- Abdullah S, Chang LY, Rahmat K, Goh KJ, Tan CT. (2012) Late-onset Nipah virus encephalitis 11 years after the initial outbreak: A case report. Neurology Asia 17:71-74. (WoS)
2010
- Sohayati AR, Sharifah SH, Olivial KJ, Maizan M, Chang LY, Latiffah H, Arshad SS, Sharina M, Syamsiah AK, Zaini CM, Epstein JH, Field HE, Daszak P, HERG. (2010) Genetic characterization of Nipah virus isolated from naturally infected Pteropus vampyrus in Malaysia. Emerging Infectious Diseases 16:1990- 1993. (WoS)
- Othman R, Hana-Marlin M, Chang LY. (2010) Proteomics analysis of Polygonum minus leaves. Journal of Biotechnology, 150:S484. (WoS)
2009
- Chang LY, AbuBakar S. (2009) Nipah virus: Phylogeny and replication. Neurology Asia 14:63-66. (WoS)
- Sharifah SH, Sohayati AR, Maizan M, Chang LY, Sharina M, Syamsiah AK, Latiffah K, Arshad SS, Zaini CM, Humes F, Daszak P, Epstein J. (2009) Genetic characterization of a Nipah virus isolated from a Pteropus vampyrus in Malaysia. Neurology Asia 14:67-69. (WoS)
2007
- Chang LY, MohdAli AR, Sharifah SH, AbuBakar S. (2007) Human neuronal cell protein responses to Nipah virus infection. Virology Journal 4:54. (WoS)
2006
- Chang LY, MohdAli AR, Sharifah SH, AbuBakar S. (2006) Nipah virus RNA synthesis in cultured pig and human cells. Journal of Medical Virology 78:1105-1112. (WoS)
- Chang LY, MohdAli AR, Sharifah SH, AbuBakar S. (2006) Quantitative estimation of Nipah virus replication kinetics in vitro. Virology Journal 3:47. (WoS)
- AR Raha, Chang LY, Sipat A, Yusoff K, Haryanti T. (2006) Expression of a thermostable xylanase gene from Bacillus coagulans ST-6 in Lactococcus lactis. Letters in Applied Microbiology 42:210-214. (WoS)
2004
- AbuBakar S, Chang LY, MohdAli AR, Sharifah SH, Yusoff K, Zamrod Z. (2004) Isolation and molecular identification of Nipah virus strains from pigs. Emerging Infectious Disease 10:2228-2230. (WoS)
2002
- AbuBakar S, Azmi A, Misbah S, Chang LY. (2002) Antigenic cell associated Dengue 2 virus proteins detected in vitro using dengue fever patients sera. Malaysian Journal of Pathology 24(1):29-36. (SCOPUS)
Book Chapter
2013
- Chang LY, Tan CT. Nipah virus infection in Viral Infections of the Human Nervous System edited by Alan C Jackson.
Article in Proceedings
2017
- Tiong VJ, Shu MH, Abd Rahman H, Wong WF, AbuBakar S, Chang LY. Role of immature dendritic cells in the dissemination of Nipah virus. Abstract submitted to 10th Leiden International Medical Students Conference, Leiden, Netherlands, 2017, p. 208 (Non-WoS/Non-SCOPUS)
2016
- Pike BL, Chang LY, Jefree Johari MI, Khor CS, Garica-Rivera JA, AbuBakar S. A cohort study to estimate the risk MERS-CoV poses to travelers and from the Middle East. Abstract submitted for American Society for Tropical Medicine and Hygiene 65th Annual Meeting, Georgia, USA, 2016 (Non-WoS/Non-SCOPUS)
- Jee PF, Chen FS, Shu MH, Tiong V, Khoo JJ, Wong WF, Raha AR, AbuBakar S, Chang LY. Surface display of the HA1 on Lactococcus lactis: A potential candidate vaccine against influenza. Abstract submitted for 5th Asian Federation of Societies for Lactic Acid Bacteria International Symposium, Taipei, Taiwan, 2016, p. 36 (Non-WoS/Non-SCOPUS)
2014
- Abd-Jamil J, Ngui R, Nellis S, Mohd Zan HA, Fauzi R, Chang LY, Lim YAL, AbuBakar S. Seroprevalence of dengue amongst inhabitants of the semi-forested and forest fringe areas of peninsular Malaysia. Abstract submitted for 16th International Congress on Infectious Diseases, Cape Town, South Africa, 2014, 43.012 (Non-WoS/Non-SCOPUS)
- Lam CW, AbuBakar S, Abd-Jamil J, Chang LY. Investigation of potential binding sites on Nipah virus glycoprotein. Abstract submitted for 16th International Congress on Infectious Diseases, Cape Town, South Africa, 2014, 51.023 (Non-WoS/Non-SCOPUS)
- Jee PF, AbuBakar S, Wong WF, Raha AR, Chang LY. Development of an influenza candidate vaccine using Lactococcus lactis. Abstract submitted for 16th International Congress on Infectious Diseases, Cape Town, South Africa, 2014, 63.013 (Non-WoS/Non-SCOPUS)
2013
- Jee PF, AbuBakar S, Raha AR, Chang LY. Construction of a non-recombinant Lactococcus lactis surface displaying influenza hemagglutinin. Proceedings of the 4th Chula International Workshop on Protein Expression and Purification Strategies, Chulalongkorn University, Bangkok, Thailand 2013, p. 41 (Non-WoS/Non-SCOPUS)
- Jee PF, AbuBakar S, Raha AR, Chang LY. Immunogenic characterization of influenza A (H1N1) hemagglutinin (HA1) fusion protein expressed in Escherichia coli. Proceedings of the International Congress of the Malaysian Society for Microbiology, Langkawi, Malaysia, 2013, p. 568-569 (Non-WoS/Non-SCOPUS)
- Lam CW, AbuBakar S, Abd-Jamil J, Chang LY. Investigation of phage-displayed truncated Nipah virus attachment glycoprotein interaction with cells Proceedings of the International Congress of the Malaysian Society for Microbiology, Langkawi, Malaysia, 2013, p. 503-504 (Non-WoS/Non-SCOPUS)
- V Tiong, S AbuBakar, LY Chang. Escherichia coli- expressed recombinant Nipah virus attachment protein maintains its immunogenicity. Proceedings of the International Congress of the Malaysian Society for Microbiology, Langkawi, Malaysia, 2013, p. 605-606 (Non-WoS/Non-SCOPUS)
2012
- Jee PF, AbuBakar S, Raha AR, Chang LY. Refolded fusion protein consisting of the N-acetylmuramidase (AcmA) anchor region and influenza hemagglutinin (HA1) retains its binding activity. Proceedings for 31st Symposium of the Malaysian Society for Microbiology, Sabah, Malaysia 2012, p. 46 (Non-WoS/Non-SCOPUS)
- Lam CW, AbuBakar S, Chang LY. Use of a single phagemid vector to produce both phage displayed and soluble form of truncated Nipah virus fusion glycoprotein. Proceedings for 31st Symposium of the Malaysian Society for Microbiology, Sabah, Malaysia 2012, p. 173 (Non-WoS/Non-SCOPUS)
- Phoon WH, AbuBakar S, Chang LY. Construction and expression of Nipah virus nucleocapsid gene in Escherichia coli. Proceedings for 31st Symposium of the Malaysian Society for Microbiology, Sabah, Malaysia 2012, p. 194 (Non-WoS/Non-SCOPUS)
- Siaw XJS, Chang LY, Yusoff K, AbuBakar S, Raha AR. Expression of recombinant Lactococcus lactis harbouring pandemic H1N1 2009 harmagglutinin (HA1) viral epitope. Proceedings for 31st Symposium of the Malaysian Society for Microbiology, Sabah, Malaysia 2012, p. 201 (Non-WoS/Non-SCOPUS)
- Tiong V, AbuBakar S, Chang LY. Permissiveness and survivability studies of Nipah virus infection of human monocytic THP-1 cells suggest a role in virus spread. Proceedings for 31st Symposium of the Malaysian Society for Microbiology, Sabah, Malaysia 2012, p. 204 (Non-WoS/Non-SCOPUS)
2011
- Jee PF, AbuBakar S, Raha AR, Chang LY. Surface display of influenza virus A antigenic protein, HA1 on Lactococcus lactis MG1363. Proceedings of the International Congress of the Malaysian Society for Microbiology, p. 398 (Non-WoS/Non-SCOPUS)
- Lam CW, AbuBakar S, Chang LY. Phage display of truncated Nipah virus attachment glycoprotein. Proceedings of the International Congress of the Malaysian Society for Microbiology, p. 188 (Non-WoS/Non-SCOPUS)
- Ong GH, Chang LY, Vadivelu J. Isolation and characterization of environmental Burkholderia pseudomallei bacteriophage. Proceedings of the International Congress of the Malaysian Society for Microbiology, p. 395 (Non-WoS/Non-SCOPUS)
- Ooi HW, AbuBakar S, Chang LY. Molecular cloning and transfection studies of Nipah virus V gene. Proceedings of the International Congress of the Malaysian Society for Microbiology, p. 254 (Non-WoS/Non-SCOPUS)
- Siaw XJS, Chang LY, Mariana NS, Yusoff K, AbuBakar S, Raha AR. Construction of Lactococcus lactis vector harbouring pandemic H1N1 2009 haemagglutinin viral epitope. Proceedings of the International Congress of the Malaysian Society for Microbiology, p. 396 (Non-WoS/Non-SCOPUS)
- Tiong V, Lam CW, Ooi HW, Phoon WH, Lew MH, AbuBakar S, Chang LY. Production of recombinant Nipah virus proteins and its application in diagnosis of a relapse case of Nipah virus infection. Proceedings of the International Congress of the Malaysian Society for Microbiology, Penang, Malaysia 2011, p. 331 (Non-WoS/Non-SCOPUS)
2009
- Sharida S, Kerk SK, Zulqarnain M, Chang LY. Kinetics of protein expression patterns in kesum leaves of Polygonum minus. Abstract submitted for 18th Scientific Meeting of Malaysian Society for Molecular Biology and Biotechnology, Kuala Lumpur, Malaysia 2009, p. 45.
2008
- Hana Marlin M, Chang LY, Othman R. Protein profiling of Polygonum minus leaves. Proceedings of the 5th Malaysian International Conference on Essential Oils, Fragrance and Flavour Materials, Kuala Lumpur, Malaysia 2008, p. 42.
- Chang LY, Sharifah SH, AbuBakar S. Molecular and genetic characterization of Nipah virus. Abstract submitted for the Nipah Virus Colloquium 2008, Kuala Lumpur, Malaysia 2008.
- Sharifah SH, Sohayati AR, Maizan M, Chang LY, Sharina M, Syamsiah AK, Latiffah K, Arshad SS, Hughes T, Daszak P, Epstein J, Aziz AJ. Molecular characterization of a recrudesced Nipah virus isolated from Pteropus vampyrus. Abstract submitted for the Nipah Virus Colloquium 2008, Kuala Lumpur, Malaysia 2008.
- Chang LY, Sharifah SH, AbuBakar S. Kinetics of Nipah virus RNA synthesis. Proceedings of the 30th Symposium of Malaysian Society for Microbiology, Kuantan, Malaysia 2008, p. 30.
2007
- Chang LY, Sharifah SH, AbuBakar S. Host cellular responses in Nipah virus infection. Proceedings of the 2nd Regional Conference on Molecular Medicine, Kuala Lumpur, Malaysia 2007, p. 59.
- AbuBakar S, Chang LY, Sharifah SH. Pathogenesis of Nipah virus infection. Proceedings of the 2nd Regional Conference on Molecular Medicine, Kuala Lumpur, Malaysia 2007, p. 17.
2006
- Chang LY, MohdAli AR, Hassan SS and AbuBakar S. Identification of human neuronal cell protein responses to Nipah virus infection. Proceedings of the Joint 3rd AOHUPO and 4th Structural Biology and Functional Genomics Conference, National University of Singapore, Singapore 2006
Mass Media(Newspaper,Radio,TV,Popular Magazine)
2020
- Chang LY. Defense against coronaviruses. Mass media in Star NIE. 22 July 2020. P. 15
2009
- Chang LY. Penyelidikan menghalang wabak virus Nipah. Mass media in MEGA Utusan Malaysia, 15 October 2009, p. 2-3.
RESEARCH PROJECT
(Project title),(Role),(Duration),(Level)
(Project title),(Role),(Duration),(Level)
Universiti Malaya COVID-19 Related Special Research Grant
Geran Penyelidikan Fakulti
Fundamental Research Grant Scheme (FRGS)
Innovate UK Grant
Frontier Research Grant
Geran Penyelidikan Universiti Malaya (UMRG)
ScienceFund
Postgraduate Research Grant(PPP)
United States Naval Medical Research Center - Asia
Geran Penyelidikan Universiti Malaya (UMRG) - Flagship
UM-MOHE HIR
Exploratory Research Grant Scheme (ERGS)
UM (Research University)
MOSTI IPHARM R&D Initiatives
MOSTI MGI Initiatives
SUPERVISION
External Supervision
(Title of Thesis),(Name of Candidates),(Institution),(Academic Level)
(Title of Thesis),(Name of Candidates),(Institution),(Academic Level)
Ongoing
- Protein Profiling of Polygonum minus Leaves, Hana Marlin Mahfodz, M0100101 (Post Graduate Student)
Completed
- NisP as a Potential Surface Anchor for Pandemic H1N1 2009 Haemagglutini (HA1) Viral Epitope in Lactococcus lactis, Stella Siaw Xiu Joan, M0100103 (Post Graduate Student)
Postgraduate Student
(Title of Thesis),(Name of Candidates),(Institution),(Academic Level)
(Title of Thesis),(Name of Candidates),(Institution),(Academic Level)
Completed
- Investigating the Potentials of Phage Therapy for Burkholderia pseudomallei Infections, Ong Guang Han, University of Malaya (UM) (Post Graduate Student)
- Epidemiologic and Molecular Characteristics of Rotavirus and Norovirus in University Malaya Medical Centre, Malaysia, Lu Kwang Shan, University of Malaya (UM) (Post Graduate Student)
- Genome-Wide Investigation of Helicobacter Pylori in RAW 264.7 Cells, Grace Tan Min Yi, University of Malaya (UM) (Post Graduate Student)
- Studies on Immune Impairment in Chronic Hepatitis C Virus Infection, Barathan Muttiah, University of Malaya (UM) (Post Graduate Student)
- Identification of Potential Cell Binding Sites on the Nipah Virus Attachment Glycoprotein using Phage Display System, Lam Chui Wan, University of Malaya (UM) (Post Graduate Student)
- Phylodynamics of Dengue Virus Type 1 in Recurring Dengue Outbreaks in Malaysia, Teoh Boon Teong, University of Malaya (UM) (Post Graduate Student)
- Interleukin-10, Interleukin-12 and Tumor Necrosis Factor-Alpha Gene Polymorphisms in Manifestations of Severe Dengue, Sam Sing Sin, University of Malaya (UM) (Post Graduate Student)
- Construction Of An Infectious Clone Of Japanese Encephalitis Virus Using Modified Pcr-Based Assembly Technique, Mohd Jefree Iskandar Johari, University of Malaya (UM) (Post Graduate Student)
- Kinetics of Protein Expression Patterns in Kesum Leaves (Persicaria minus), Sharida Shoib, University of Malaya (UM) (Post Graduate Student)
Ongoing
- Dengue Virus Type 3 in Malaysia: Diversity, Origin, and Spread, Tan Kim Kee, University of Malaya (UM) (Post Graduate Student)
- Influenza Hemagglutinin 1 (HA1) Surface-Displayed on Lactococcus Lactis in the Induction of Protective Mucosal Immunity against Influenza Virus, Jee Pui Fong, University of Malaya (UM) (Post Graduate Student)
- Decrypting the Intricate Interplay between Chlamydia trachomatis and Host Cell Mitochondria, Cheong Heng Choon, University of Malaya (UM) (Post Graduate Student)
- The Role of Leukocytes in the Dissemination of Nipah Virus, Tiong Vunjia, University of Malaya (UM) (Post Graduate Student)
- Molecular Characterization of Nipah Virus Replication in Tick Cells, Phoon Wai Hong, University of Malaya (UM) (Post Graduate Student)
- ELISA-Based Assay using Recombinant Nipah Virus Antigens for Nipah Surveillance among Indigenous Populations in Peninsular Malaysia, Yong Ming Yen, University of Malaya (UM) (Post Graduate Student)
- Modulation of Host Immune Responses by Chlamydial Plasmid Encoded Pgp3 Protein in Patients with Genital Chlamydia Trachomatis Infections, Cheong Heng Choon, University of Malaya (UM) (Post Graduate Student)
- Evaluation Of Amino Acid Changes In Nipah Virus V Protein In Its Function As An Immune Antagonist, Oon Syiak Syin, University of Malaya (UM) (Post Graduate Student)
PATENT/IPR
(Product Name),(Type),(Level)
(Product Name),(Type),(Level)
- A fusion protein and a method for producing thereof, Patent (National)
- A fusion fragment encoding an influenza A virus hemagglutinin and a method for preparing the same, Patent (National)
- Detection and quantitation method for Nipah and Hendra viruses, Patent (National)
ACADEMIC/PROFESSIONAL SERVICES
Evaluation Activity
(Activity),(Duration),(Category)
(Activity),(Duration),(Category)
Expert Linkages
(Linkages Description),(Organisation),(Duration of Involvement),(Level)
(Linkages Description),(Organisation),(Duration of Involvement),(Level)
Academic/Technical Contribution
(Activity),(Organisation),(Duration),(Role)
(Activity),(Organisation),(Duration),(Role)
AWARD AND STEWARDSHIP
(Name of Award/Stewardship),(Awarding Institution),(Year Awarded),(Type of Award)
(Name of Award/Stewardship),(Awarding Institution),(Year Awarded),(Type of Award)
- Travel award to Asia Pacific Biosafety Association 12th Biosafety Conference 2017, United States Department of State, 2017 (OTHERS)
- Travel award to Asia Pacific Biosafety Association 10th Biosafety Conference 2015, United States Department of State, 2015 (OTHERS)
- CERTIFICATE OF EXCELLENT SERVICE, University of Malaya, 2014 (CERTIFICATE)
- Travel award to Asia Pacific Biosafety Association 9th Biosafety Conference 2014, United States Department of State, 2014 (OTHERS)
- EXCELLENCE SERVICE AWARD, University of Malaya, 2013 (CERTIFICATE)
- Anugerah Perkhidmatan Cemerlang, Universiti Malaya, 2013 (SPECIAL)
- CERTIFICATE OF EXCELLENT SERVICE, University of Malaya, 2012 (CERTIFICATE)
- Travel award to attend the Biosafety and Biosecurity Training Course 2012 at Fort Collins, Colorado, U.S., Biosafety Engagement Program, Department of State, U.S., 2012 (SPECIAL)
- Travel award to American Society for Microbiology 112th General Meeting at San Francisco, California, U.S., Biosafety Engagement Program, Department of State, U.S., 2012 (SPECIAL)
- Travel award to Asia Pacific Biosafety Association 6th Biosafety Conference 2011, National Institutes of Health, U.S., 2011 (SPECIAL)
- Travel award to attend IANIS 2010 2nd International Conference on Neuroinfection and Worldwide Impact, St Denis, Reunion Island, Embassy of France, Malaysia, 2010 (RESEARCH)
- Travel award to Train the Trainer Course in Laboratory Biosafety Principles and Practices, Singapore Polytechnic Institute, Singapore, Consolidated Safety Services, U.S. and U.S. National Institutes of Health, 2010 (SPECIAL)
- Travel award to attend BSL3 Science and Safety Course (40-hour biosafety training), Emory University, Atlanta, Georgia, U.S., Biosafety Engagement Program, Department of State, U.S., 2010 (SPECIAL)
- Member of Nipah Encephalitis Investigation Team, Universiti Malaya as joint recipient winners of the Inaugural Merdeka Award 2008 under the Health, Science and Technology Category., ExxonMobil, PETRONAS and Shell, 2009 (RESEARCH)
- 2nd prize winner for 2008 Merck Young Scientist Award., Merck Sdn Bhd, 2008 (RESEARCH)
- Research attachment to Institute of Microbiology, University of Greifswald, Germany, National Science Fellowship, Ministry of Science, Technology and Innovation of Malaysia, 2004 (RESEARCH)
- Travel award for Pasteur-Asia Virology course 2004 in HKU-Pasteur Research Centre, Hong Kong, Institut Pasteur Paris and HKU-Pasteur Research Centre, 2004 (RESEARCH)
- National Science Fellowship, Ministry of Science, Technology and the Environment of Malaysia, 2001 (SPECIAL)
CONSULTANCY PROJECT
(Project title),(Organisation),(Duration),(Role),(Level)
(Project title),(Organisation),(Duration),(Role),(Level)
- International Consultation on Research to Combat Nipah Virus Disease, World Health Organization - South-East Asia, 01/11/2018 to 01/11/2019 (International)
- Malaysian Code of Practice for the Care and Use of Animals for Scientific Purposes, Department of Veterinary Services, 01/11/2018 to 01/11/2018 (National)
- Strengthening Biosafety and Biosecurity Competency in South East Asia Program - Malaysia, Malaysian Biosafety and Biosecurity Association, 01/12/2017 to 01/12/2017 (National)
- Development of Training Materials and Tools for Strengthening Biosafety and Biosecurity Competency in South East Asia, Malaysian Biosafety and Biosecurity Association, 01/12/2017 to 01/12/2017 (National)
- Strengthening Biosafety and Biosecurity Competency in South East Asia Program - Malaysia, Malaysian Biosafety and Biosecurity Association, 01/12/2016 to 01/12/2016 (National)
- Biosafety and Biosecurity Manual & Code of Conduct Document Development, Institut Biologi Sistem, 01/11/2016 to 01/11/2016 (National)
- Pra-Bengkel dan Bengkel Penghasilan Manual Latihan Makmal Biosafety Level 2 Peringkat Kebangsaan, National Public Health Laboratory, Ministry of Health, 01/12/2015 to 01/12/2015 (National)
- Perbincangan ulasan umum "Malaysia Laboratory Biosafety and Biosecurity Policy and Guideline", National Public Health Laboratory, Ministry of Health, 01/01/2014 to 01/01/2014 (National)
- Pra-Bengkel Penghasilan Polisi, Garispanduan dan Senarai Semak Biosafety & Biosecurity Perkhidmatan Makmal kesihatan Peringkat Kebangsaan, National Public Health Laboratory, Ministry of Health, 01/12/2013 to 01/12/2013 (National)
- Bengkel Penyediaan MySED (2012-2015) Workplan, Ministry of Health Malaysia, 01/01/2012 to 01/01/2012 (National)
- MOSTI IPharm Project Monitoring Team for TechnoFund Project - Proof of Principle Study: Rapid Detection of Dengue Virus (Single Serotype) By A Laboratory Based Surface Acoustic Wave Biosensor, MOSTI IPharm, 01/04/2011 to 01/04/2011 (National)
- Bengkel Percambahan Fikiran Penyediaan dan Penetapan Biological Weapons (BW) Selected Agents List Rang Undang-Undang Konvensyen Senjata Biologi (RU KSB), Science and Technology Research Institute for Defence, 01/04/2011 to 01/04/2011 (National)
- Sharing experience between EU and SEA countries on the reinforcement of legislations and regulations in the field of biosafety and biosecurity, as well as relevant laboratories management systems through Regional Centre of Excellence, European Union, 01/04/2010 to 01/04/2012 (International)
PAPER PRESENTED
(Title),(Event),(Date Presented),(Organiser),(Level)
(Title),(Event),(Date Presented),(Organiser),(Level)
INVITED SPEAKER
ORAL PRESENTER
POSTER PRESENTER
PRESENTER