DR. AIN ZUBAIDAH BINTI AYOB

Senior Lecturer

AREAS OF EXPERTISE

PhD, (Molecular Medicine)
Universiti Malaya (UM)
MSC, (APPLIED BIOPHARMACEUTICAL BIOTECHNOLOGY AND ENTREPRENEURSHIP)
University of Nottingham
BSC (Hons), (Biotechnology)
University of Nottingham

MALAYSIAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, MEMBER
2024 to 2024 (National)
MALAYSIAN SOCIETY FOR MOLECULAR BIOLOGY AND BIOTECHNOLOGY (MSMBB), MEMBER
2024 to present (National)
MALAYSIAN SOCIETY FOR MOLECULAR BIOLOGY AND BIOTECHNOLOGY, MEMBER
2023 to 2023 (National)
MALAYSIAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, MEMBER
2023 to 2023 (National)

YSN-ASM Young Investigator Award for Best Poster
Young Scientist Network-Academy of Science Malaysia, 2017 (National)

Ayob AZ, Ramasamy TS*. Prolonged hypoxia switched on cancer stem cell-like plasticity in HepG2 tumourspheres cultured in serum-free media. In Vitro Cell Dev Biol Anim. 2021 Oct;57(9):896-911. doi: 10.1007/s11626-021-00625-y.
Ain Zubaidah Ayob & Thamil Selvee Ramasamy* (2018). Cancer stem cells as key drivers of tumour progression. Journal of Biomedical Science (2018) 25:20
Ramasamy TS, Ayob AZ, Myint HHL, Thiagarajah S, Amini F(2015). Targeting Colorectal Cancer Stem Cells Using Curcumin and Curcumin Analogues: Insights into the Mechanism of the Therapeutic Efficacy. Cancer Cell International 15:96.

Ayob, A. Z., Ramasamy, T. S. Enrichment of hepatic cancer stem-like cells in different in vitro cultures systems exhibiting distinct molecular and cellular characteristics recapitulate tumour heterogeneity. MTERMS 2016. Front. Bioeng. Biotechnol. doi: 10.3389/conf.FBIOE.2016.02.00017

2023 - 2026, Fundamental Research Grant Scheme (FRGS)
Elucidating The Mechanistic Roles Of Spock1, A Matricellular Proteoglycan, As A Modulator Of Epithelial-mesenchymal Transition And Cancer Stem Cells Plasticity In Hepatocellular Carcinoma Cell Lines ( Principal Investigator(PI))

Maximising the Success of Your qPCR Experiment, MOMPES QPCR WORKSHOP, Department of Molecular Medicine (National) (27 Jul 2023 - 27 Jul 2023)
Molecular and Cell Biology, 7th Opthalmology Basic Science Examination (MedEx) Preparatory Course, Departmnent of Ophthalmology, Faculty of Medicine, UM (National) (26 Apr 2023 - 28 Apr 2023)
Unravelling the Molecular Regulatory Networks of Cancer Stem Cells Plasticity, Live Webinar Series: BREAKFAST@UMHEALTH , UM Health (University) (22 Feb 2023 - 22 Feb 2023)

Integrated microRNA and mRNA regulatory networks associated with cancer stem-like cells in hepatocellular carcinoma., 2nd PhD Research Symposium in Health Sciences and Biomedicine., Universidad Aut noma de Madrid (International) (21 May 2021 - 21 May 2021)

Ramasamy T.S. Integrated miRNA-mRNA analysis revealed distinct molecular signatures and regulatory networks in cancer stem-like cell models of hepatocellular carcinoma., Virtual Keystone Symposia. Cancer Stem Cells: Advances in Biology and Clinical Translation eSymposia, eSymposia Keystone (International) (19 May 2021 - 21 May 2021)
Effects of hypoxia on the induction of cancer stem cells-like properties in tumourspheres derived from HepG2 cells, Tissue Engineering and Regenerative Medicine Postgraduate Symposium (TERMSYMPO) , Tissue Engineering Centre (TEC), UKM and TESMA (National) (07 Nov 2017 - 07 Nov 2017)
Enrichment of hepatic cancer stem-like cells in different in vitro cultures systems exhibiting distinct molecular and cellular characteristics recapitulate tumour heterogeneity. , 6th Malaysian Tissue Engineering and Regenerative Medicine Scientific Meeting , TESMA (National) (17 Nov 2016 - 18 Nov 2016)
Association of rhythmicity between circadian clock and stemness properties in hepatocellular carcinoma., Faculty of Medicine Research Day , Faculty of Medicine (University) (31 May 2016 - 31 May 2016)

(2022) Biomedscience Fyp Proposal Defence - Fatin Farhanah - Investigating The Secretion of Pro- Inflmmatory Factors in Ct-26 Murine Colorectal Cancer Cell Line, University, (Internal Assessor)
(2022) Biomedscience Fyp Proposal - Lim Wei Yue - Investigation of Novel Interaction Between Microrna Let-7i-5p and Hoxa9 Gene in Acute Myeloid Leukaemia Cells, University, (Internal Examiner)
(2022) Masters Proposal Defense - Qistina Marsha Aziz Zainal - Circadian Rhythmicity in Milk: Elucidating Its Roles in Maintaining Oral Health in Infants, University, (Internal Examiner)

(2024) Academic Advisor - MBBS Stage 1 & 2 Cohort 2022/2023, University, (Academic Advisor)

(2024) INVESTIGATION OF THE ROLES OF SPOCK1 IN THE INTERPLAY BETWEEN EPITHELIAL-MESENCHYMAL TRANSITION AND CANCER STEM CELL PLASTICITY IN HEPATOCELLULAR CARCINOMA CELL LINES, RACHEL HOE HUEY XUAN

(2024) MIC4001-Enhancing Sensitivity of Food Screening Device for Foodborne Pathogen Detection
(2023) MIC4001 BiomedSci - A Study to Characterise Sorafenib Resistance in 2D and 3D cultures of HepG2 cells

Panel Penemuduga Bagi Kemasukan Ke MBBS 2023/2024, (13 Jul 2021 - 15 Jul 2021), (07 Jun 2023 - 21 Jun 2023) (University)
Science Outreach : Lab of Wonders Workshop, (24 May 2023 - 31 May 2023) (National)