CURRICULUM VITAE

PhD, (Molecular Medicine)
Universiti Malaya (um)
MSC, (APPLIED BIOPHARMACEUTICAL BIOTECHNOLOGY AND ENTREPRENEURSHIP)
University of Nottingham
BSC (Hons), (Biotechnology)
University of Nottingham

PENYELARAS JAWATANKUASA TASK-FORCE UNTUK MEMBANGUNKAN KURSUS MICRO CREDENTIAL DI JABATAN PERUBATAN MOLEKUL, FAKULTI PERUBATAN
30 Jul 2025 - 30 Jul 2026 (Department)

Best Overall Oral Presentation
2024, 14TH MALAYSIA SYMPOSIUM OF BIOMEDICAL SCIENCE 2024, (National)
2023 Iq Consortium/aaalac International Global 3rs Award - Pacific Rim Recipient
2023, IQ Consortium/AAALAC International , (International)
YSN-ASM Young Investigator Award for Best Poster
2017, Young Scientist Network-Academy of Science Malaysia, National

Ayob AZ, Ramasamy TS*. Prolonged hypoxia switched on cancer stem cell-like plasticity in HepG2 tumourspheres cultured in serum-free media. In Vitro Cell Dev Biol Anim. 2021 Oct;57(9):896-911. doi: 10.1007/s11626-021-00625-y.
Ain Zubaidah Ayob & Thamil Selvee Ramasamy* (2018). Cancer stem cells as key drivers of tumour progression. Journal of Biomedical Science (2018) 25:20
Ramasamy TS, Ayob AZ, Myint HHL, Thiagarajah S, Amini F(2015). Targeting Colorectal Cancer Stem Cells Using Curcumin and Curcumin Analogues: Insights into the Mechanism of the Therapeutic Efficacy. Cancer Cell International 15:96.

Ayob, A. Z., Ramasamy, T. S. Enrichment of hepatic cancer stem-like cells in different in vitro cultures systems exhibiting distinct molecular and cellular characteristics recapitulate tumour heterogeneity. MTERMS 2016. Front. Bioeng. Biotechnol. doi: 10.3389/conf.FBIOE.2016.02.00017

Cancer Biology (Cancer stem cells, Epithelial-mesenchymal Transition (EMT), Chemoresistance, Cancer plasticity, 3D models)
Gene expression (MicroRNA, Transcriptomics, Integrative Omics)

2024 - 2027, Fundamental Research Grant Scheme (FRGS)
Identifying Hfpef (heart Failure With Preserved Ejection Fraction): The Role Of Molecular And Biochemical Signatures Of Ferroptosis ( Co-Researcher)
2024 - 2027, UNIVERSITI MALAYA RESEARCH EXCELLENCE GRANT (UMREG)
Elucidating The Neuroinflammation Modulatory Effects Of Rhizome Extracts From Three Zingiber Species In An Alzheimer?s Disease Cell Model ( Co-Researcher)
2023 - 2026, Fundamental Research Grant Scheme (FRGS)
Elucidating The Mechanistic Roles Of Spock1, A Matricellular Proteoglycan, As A Modulator Of Epithelial-mesenchymal Transition And Cancer Stem Cells Plasticity In Hepatocellular Carcinoma Cell Lines ( Principal Investigator(PI))

2023 - 2025, International Funding
Decoding The Mechanisms Of Cancer Stem Cell Plasticity For Therapeutic Development ( Co-Researcher)

MOLECULAR AND CELL BIOLOGY, 9th Ophthalmology Basic Science Examination (MedEx) Preparatory Course, Department of Ophtalmology, Faculty of Medicine, Universiti Malaya (National) (03 Sep 2024 - 06 Sep 2024)
Maximising the Success of Your qPCR Experiment, MOMPES QPCR WORKSHOP, Department of Molecular Medicine (National) (27 Jul 2023 - 27 Jul 2023)
Molecular and Cell Biology, 7th Opthalmology Basic Science Examination (MedEx) Preparatory Course, Departmnent of Ophthalmology, Faculty of Medicine, UM (National) (26 Apr 2023 - 28 Apr 2023)
Unravelling the Molecular Regulatory Networks of Cancer Stem Cells Plasticity, Live Webinar Series: BREAKFAST@UMHEALTH , UM Health (University) (22 Feb 2023 - 22 Feb 2023)

Development of HepG2-derived Spheroid Model for Studying Drug Response in Hepatocellular Carcinoma - Presented by Choe Wee Ling, 14TH MALAYSIAN SYMPOSIUM OF BIOMEDICAL SCIENCE 2024, UNIVERSITY PUTRA MALAYSIA (National) (01 Jun 2024 - 02 Jun 2024)
Integrated microRNA and mRNA regulatory networks associated with cancer stem-like cells in hepatocellular carcinoma., 2nd PhD Research Symposium in Health Sciences and Biomedicine., Universidad Aut noma de Madrid (International) (21 May 2021 - 21 May 2021)

Enhanced SPOCK1 Expression is Associated with Cancer Stem Cell Plasticity in TGF- 1-Induced Partial EMT in HepG2 Cells (Rachel Hoe Huey Xuan), 18th Annual Meeting of the Korean Society of Medical Oncology & 2025 International Conference (KSMO 2025), Korean Society of Medical Oncology (International) (03 Sep 2025 - 05 Sep 2025)
Ramasamy T.S. Integrated miRNA-mRNA analysis revealed distinct molecular signatures and regulatory networks in cancer stem-like cell models of hepatocellular carcinoma., Virtual Keystone Symposia. Cancer Stem Cells: Advances in Biology and Clinical Translation eSymposia, eSymposia Keystone (International) (19 May 2021 - 21 May 2021)
Effects of hypoxia on the induction of cancer stem cells-like properties in tumourspheres derived from HepG2 cells, Tissue Engineering and Regenerative Medicine Postgraduate Symposium (TERMSYMPO) , Tissue Engineering Centre (TEC), UKM and TESMA (National) (07 Nov 2017 - 07 Nov 2017)
Enrichment of hepatic cancer stem-like cells in different in vitro cultures systems exhibiting distinct molecular and cellular characteristics recapitulate tumour heterogeneity. , 6th Malaysian Tissue Engineering and Regenerative Medicine Scientific Meeting , TESMA (National) (17 Nov 2016 - 18 Nov 2016)
Association of rhythmicity between circadian clock and stemness properties in hepatocellular carcinoma., Faculty of Medicine Research Day , Faculty of Medicine (University) (31 May 2016 - 31 May 2016)

(2025) THE ROLE OF MOLECULAR AND BIOCHEMICAL SIGNATURES OF FERROPTOSIS IN RELATION TO HFPEF (HEART FAILURE WITH PRESERVED EJECTION FRACTION), TEO MING LE
(2025) INVESTIGATION OF THE POTENTIAL OF LUTEOLIN IN MITIGATING SORAFENIB RESISTANCE IN HEPATOCELLULAR CARCINOMA, XIE KANGZHEN
(2025) INVESTIGATION OF THE ROLES OF SPOCK1 IN THE INTERPLAY BETWEEN EPITHELIAL-MESENCHYMAL TRANSITION AND CANCER STEM CELL PLASTICITY IN HEPATOCELLULAR CARCINOMA CELL LINES, RACHEL HOE HUEY XUAN

(2024) MIC4001-Enhancing Sensitivity of Food Screening Device for Foodborne Pathogen Detection
(2023) MIC4001 BiomedSci - A Study to Characterise Sorafenib Resistance in 2D and 3D cultures of HepG2 cells

DR. AIN ZUBAIDAH BINTI AYOB