Curriculum Vitae

DR. AIN ZUBAIDAH BINTI AYOB

Senior Lecturer
  • Department of Molecular Medicine
    Faculty of Medicine
  • 03-79677875

AREAS OF EXPERTISE

  • CELL BIOLOGY
    CHEMORESISTANCE, EPITHELIAL-MESENCHYMAL TRANSITION
  • NUCLEIC ACIDS
    GENE EXPRESSION, MICROARRAY, MICRORNA

ACADEMIC QUALIFICATION

  • PhD, (Molecular Medicine)
    Universiti Malaya (UM)
  • MSC, (Applied Biopharmaceutical Biotechnology and Entrepreneurship)
    University of Nottingham
  • BSC (Hons), (Biotechnology)
    University of Nottingham

MEMBERSHIPS

  • MALAYSIAN SOCIETY FOR MOLECULAR BIOLOGY AND BIOTECHNOLOGY, MEMBER
    2023 to 2023 (National)
  • MALAYSIAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, MEMBER
    2023 to 2023 (National)

AWARD AND STEWARDSHIP

  • YSN-ASM Young Investigator Award for Best Poster
    Young Scientist Network-Academy of Science Malaysia, 2017 (National)

PUBLICATIONS

Article in Journal
  1. Ayob AZ, Ramasamy TS*. Prolonged hypoxia switched on cancer stem cell-like plasticity in HepG2 tumourspheres cultured in serum-free media. In Vitro Cell Dev Biol Anim. 2021 Oct;57(9):896-911. doi: 10.1007/s11626-021-00625-y.
  2. Ain Zubaidah Ayob & Thamil Selvee Ramasamy* (2018). Cancer stem cells as key drivers of tumour progression. Journal of Biomedical Science (2018) 25:20
  3. Ramasamy TS, Ayob AZ, Myint HHL, Thiagarajah S, Amini F(2015). Targeting Colorectal Cancer Stem Cells Using Curcumin and Curcumin Analogues: Insights into the Mechanism of the Therapeutic Efficacy. Cancer Cell International 15:96.
Article in Proceeding
  1. Ayob, A. Z., Ramasamy, T. S. Enrichment of hepatic cancer stem-like cells in different in vitro cultures systems exhibiting distinct molecular and cellular characteristics recapitulate tumour heterogeneity. MTERMS 2016. Front. Bioeng. Biotechnol. doi: 10.3389/conf.FBIOE.2016.02.00017

RESEARCH PROJECT

National
  1. 2023 - 2026, Fundamental Research Grant Scheme (FRGS)
    Elucidating The Mechanistic Roles Of Spock1, A Matricellular Proteoglycan, As A Modulator Of Epithelial-mesenchymal Transition And Cancer Stem Cells Plasticity In Hepatocellular Carcinoma Cell Lines ( Principal Investigator(PI))

PAPER PRESENTED

INVITED SPEAKER
  1. Maximising the Success of Your qPCR Experiment, MOMPES QPCR WORKSHOP, Department of Molecular Medicine (National) (27 Jul 2023 - 27 Jul 2023)
  2. Molecular and Cell Biology, 7th Opthalmology Basic Science Examination (MedEx) Preparatory Course, Departmnent of Ophthalmology, Faculty of Medicine, UM (National) (26 Apr 2023 - 28 Apr 2023)
  3. Unravelling the Molecular Regulatory Networks of Cancer Stem Cells Plasticity, Live Webinar Series: BREAKFAST@UMHEALTH , UM Health (University) (22 Feb 2023 - 22 Feb 2023)
ORAL PRESENTER
  1. Integrated microRNA and mRNA regulatory networks associated with cancer stem-like cells in hepatocellular carcinoma., 2nd PhD Research Symposium in Health Sciences and Biomedicine., Universidad Aut noma de Madrid (International) (21 May 2021 - 21 May 2021)
POSTER PRESENTER
  1. Ramasamy T.S. Integrated miRNA-mRNA analysis revealed distinct molecular signatures and regulatory networks in cancer stem-like cell models of hepatocellular carcinoma., Virtual Keystone Symposia. Cancer Stem Cells: Advances in Biology and Clinical Translation eSymposia, eSymposia Keystone (International) (19 May 2021 - 21 May 2021)
  2. Effects of hypoxia on the induction of cancer stem cells-like properties in tumourspheres derived from HepG2 cells, Tissue Engineering and Regenerative Medicine Postgraduate Symposium (TERMSYMPO) , Tissue Engineering Centre (TEC), UKM and TESMA (National) (07 Nov 2017 - 07 Nov 2017)
  3. Enrichment of hepatic cancer stem-like cells in different in vitro cultures systems exhibiting distinct molecular and cellular characteristics recapitulate tumour heterogeneity. , 6th Malaysian Tissue Engineering and Regenerative Medicine Scientific Meeting , TESMA (National) (17 Nov 2016 - 18 Nov 2016)
  4. Association of rhythmicity between circadian clock and stemness properties in hepatocellular carcinoma., Faculty of Medicine Research Day , Faculty of Medicine (University) (31 May 2016 - 31 May 2016)

ACADEMIC/PROF. SERVICES

Evaluation
  1. (2022) Biomedscience Fyp Proposal Defence - Fatin Farhanah - Investigating The Secretion of Pro- Inflmmatory Factors in Ct-26 Murine Colorectal Cancer Cell Line, University, (Internal Assessor)
  2. (2022) Biomedscience Fyp Proposal - Lim Wei Yue - Investigation of Novel Interaction Between Microrna Let-7i-5p and Hoxa9 Gene in Acute Myeloid Leukaemia Cells, University, (Internal Examiner)
  3. (2022) Masters Proposal Defense - Qistina Marsha Aziz Zainal - Circadian Rhythmicity in Milk: Elucidating Its Roles in Maintaining Oral Health in Infants, University, (Internal Examiner)
Mentoring
  1. (2024) Academic Advisor - MBBS Stage 1 & 2 Cohort 2022/2023, University, (Academic Advisor)

TEACHING

Bachelor
  1. (2022) DIA1003 - Biochemistry

SOCIAL RESPONSIBILITY ACTIVITIES

  • Panel Penemuduga Bagi Kemasukan Ke MBBS 2023/2024, (13 Jul 2021 - 15 Jul 2021), (07 Jun 2023 - 21 Jun 2023) (University)
  • Science Outreach : Lab of Wonders Workshop, (24 May 2023 - 31 May 2023) (National)